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SETKARRQDRRTAVTTAAILDAAEGLFAERGFHAVTVDAIAEAAGLAVGSIYHHFKNKERLYLALVERAL SVNEQAMAVAFGQGRTPMEELRAASDAYCDFHLQNPGYFRMIALRTLDVPPGDMADEVERRIADKVEALV GDIADVLRRADAAGEVHCPDPVRVSIFLWGAWNGVLSLNLRPDRLRLEPAEMQRVLELGRDIIERGLVRT *
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0483c | - | - | 100% (211) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2290 | - | 2e-13 | 37.38% (107) | transcriptional regulator TetR |
| M. abscessus ATCC 19977 | MAB_0476c | - | 7e-12 | 34.92% (126) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2534 | - | 1e-10 | 36.55% (145) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2460 | - | 1e-11 | 50.82% (61) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv2506 | - | 1e-10 | 36.55% (145) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00717 | - | 8e-11 | 29.14% (151) | putative TetR-family transcriptional regulator |
| M. marinum M | MMAR_3853 | - | 1e-11 | 34.93% (146) | putative regulatory protein |
| M. avium 104 | MAV_5253 | - | 1e-12 | 31.53% (203) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6807 | - | 3e-11 | 50.82% (61) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2855 | - | 1e-10 | 27.78% (198) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_3785 | - | 8e-12 | 34.93% (146) | putative regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_4572 | - | 7e-11 | 27.96% (186) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2460|M.gilvum_PYR-GCK --------MVERWT-------------------RERRLEHTRSVLLDAAE
MSMEG_6807|M.smegmatis_MC2_155 --------MVERWT-------------------RERRLEHTRSLLLDAAE
Mb2534|M.bovis_AF2122/97 --------MTASAPDGRPGQPEAT-------NRRSQLKSDRRFQLLAAAE
Rv2506|M.tuberculosis_H37Rv --------MTASAPDGRPGQPEAT-------NRRSQLKSDRRFQLLAAAE
MMAR_3853|M.marinum_M --------MAASAPDEQTATP----------NRRSQQKSDRRLQLLSAAE
MUL_3785|M.ulcerans_Agy99 --------MAASAPDEQTATP----------NRRSQQKSDRRLQLLSAAE
MAB_0483c|M.abscessus_ATCC_199 --------MSETKAR-----------------RQDRRTAVTTAAILDAAE
MAV_5253|M.avium_104 --------MESKRR------------------TQEERSAATRDALIAAAR
Mvan_4572|M.vanbaalenii_PYR-1 --------MADVSAPRQRRHR-----------APRGAGEQLRAEILDAAT
MLBr_00717|M.leprae_Br4923 --------MTTARR--------------------RLSPEDRRAELLALGA
TH_2855|M.thermoresistible__bu LSQSPDNATSSSRAGSGAGSGAGSGAEPIGRDTPRRRPRIRPEEIVSAAA
:: .
Mflv_2460|M.gilvum_PYR-GCK EVFAEKG-FTPATLDDIARAAGYTKGAIYKHFDTKEELFLAVSDRYWRRY
MSMEG_6807|M.smegmatis_MC2_155 NVFSEKG-FTAATLDDIAFAAGYTKGAIYKHFATKEDLFLAVSDRYWRRY
Mb2534|M.bovis_AF2122/97 RLFAERG-FLAVRLEDIGAAAGVSGPAIYRHFPNKESLLVELLVGVSARL
Rv2506|M.tuberculosis_H37Rv RLFAERG-FLAVRLEDIGAAAGVSGPAIYRHFPNKESLLVELLVGVSARL
MMAR_3853|M.marinum_M RLFAERG-FLAVRLEDIGAAAGISGPAIYRHFPNKESLLVELLVGISSRL
MUL_3785|M.ulcerans_Agy99 RLFAERG-FLAVRLEDIGAAAGISGPAIYRHFPNKESLLVELLVGISSRL
MAB_0483c|M.abscessus_ATCC_199 GLFAERG-FHAVTVDAIAEAAGLAVGSIYHHFKNKERLYLALVERALS-V
MAV_5253|M.avium_104 KLWGLRG-YTEVGTPEIAAAAGVTRGAMYHQFADKAALFRAVVEAVEQDV
Mvan_4572|M.vanbaalenii_PYR-1 DLLLETGDEKAVSIRSVAQRVGVTPPSIYLHFVDKTALLDAVCGRYFEKL
MLBr_00717|M.leprae_Br4923 EVFGKRP-YDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVVKDEADRL
TH_2855|M.thermoresistible__bu EFFAREG-YANVGMRDVAEAVGIRGASLYHHFGSKEEILYAICLTVTKEP
. . :. .* :* * * : :
Mflv_2460|M.gilvum_PYR-GCK FDNFAEVMSSA-SRVGADELDEIAERWRQLSIDRGAEHAALGL-----EF
MSMEG_6807|M.smegmatis_MC2_155 FDNFAEVMASA-ASVGARELDEIAKRWRQLSVDRGAEQAALGL-----EF
Mb2534|M.bovis_AF2122/97 LAGARDVTTRS-ANL-AAALDGLIEFHLDFALGEADLIRIQDR-----DL
Rv2506|M.tuberculosis_H37Rv LAGARDVTTRS-ANL-AAALDGLIEFHLDFALGEADLIRIQDR-----DL
MMAR_3853|M.marinum_M LAGARQVTTNS-NDA-AAALDGLIDFHLDFALGEPDLIRIQDR-----DL
MUL_3785|M.ulcerans_Agy99 LAGARQVTTNS-NDA-AAALDGLIDFHLDFALGEPDLIRIQDR-----DL
MAB_0483c|M.abscessus_ATCC_199 NEQAMAVAFGQ-GRTPMEELRAASDAYCDFHLQNPGYFRMIALR----TL
MAV_5253|M.avium_104 MARMAVVVAESGASTPTDAIRAAVDAWLEVSADP----EVRQLI----LL
Mvan_4572|M.vanbaalenii_PYR-1 DEEMQEVAGAA--ATALDVLRAQGMAYVRFALKNPVLYRIAMMGPGSPGS
MLBr_00717|M.leprae_Br4923 YAATNIPPPAG--LTMFEEVRVGVLAYMAYHKQNPEAAWAAYVG--LGRS
TH_2855|M.thermoresistible__bu NELNLPLLDAA--GTPAERLSALIRAHLEHLIRRRVEHLVALH-----DI
:
Mflv_2460|M.gilvum_PYR-GCK TLYLLRNPEARERVEAKRAEVVDQ----------LAEFIVEGMSQLGATL
MSMEG_6807|M.smegmatis_MC2_155 TLYLKRNPEARDRVAAKRSEVVAQ----------LTAFIVASIEKLGATL
Mb2534|M.bovis_AF2122/97 AHLPAVAERQVRKAQRQYVEVWVG----------VLRELNPGLAEADARL
Rv2506|M.tuberculosis_H37Rv AHLPAVAERQVRKAQRQYVEVWVG----------VLRELNPGLAEADARL
MMAR_3853|M.marinum_M GHLPAAAERQVRKAQRQYVEIWVG----------VLRQLDPGLAEADARL
MUL_3785|M.ulcerans_Agy99 GHLPAAAERQVRKAQRQYVEIWVG----------VLRQLDPGLAEADARL
MAB_0483c|M.abscessus_ATCC_199 DVPPGDMADEVERRIADKVEALVG----------DIADVLRRADAAGEVH
MAV_5253|M.avium_104 DAPSVLGWAEFRDVAQRYSLGMTE----------QLLTEAIRAGELAEQP
Mvan_4572|M.vanbaalenii_PYR-1 DVDVALNSSAFGHLLMSVQALIAEGVYPQADPTMLALELWTAVHGIAAML
MLBr_00717|M.leprae_Br4923 DPVLLGIDDEAKNRQMEHIMSRIGDVVSVVPESKLHPDIERDLRVIVHGW
TH_2855|M.thermoresistible__bu NSLTPEHRAIIDDLRRYYQRRVRD---------VIVAGVRSGEFDVPDPK
Mflv_2460|M.gilvum_PYR-GCK LIEPS------TFARALVATSDSVVLGSQLDAVDLY--RPMVEMYVSVIK
MSMEG_6807|M.smegmatis_MC2_155 LISPE------TFAHALVATSDSVVLSSELDNVDLY--RPMVEMYASMIK
Mb2534|M.bovis_AF2122/97 MAHAV------FGLLNSTPHSMKAADSKPARTVRAR--AVLRAMTVAALS
Rv2506|M.tuberculosis_H37Rv MAHAV------FGLLNSTPHSMKAADSKPARTVRAR--AVLRAMTVAALS
MMAR_3853|M.marinum_M MAHAA------FGLLNSTPHSMKSADTKSACAPHSR--AVMRAMTVAALT
MUL_3785|M.ulcerans_Agy99 MAHAA------FGLLNSTPHSMESADTKSACAPHSR--AVMRAMTVAALT
MAB_0483c|M.abscessus_ATCC_199 CPDPVRVS---IFLWGAWNGVLSLNLRPDRLRLEPA--EMQRVLELGRDI
MAV_5253|M.avium_104 VRPLAHVL---IGALDEAAMVIATADDPDRARRETR--QVLQRLVDGMFD
Mvan_4572|M.vanbaalenii_PYR-1 ISRPYLPW---GGAEEFADRLMRAVCCGQALSVAIRPDESPREIMTWLKE
MLBr_00717|M.leprae_Br4923 LAFTFEVCRQRIMDPSTDADRLADSCAHALLDAIARVPEISKELADAMAI
TH_2855|M.thermoresistible__bu LAALL-----ILDALNGVSGWFHPDRGHSLPDVIAAYTEMIVERVLRARI
Mflv_2460|M.gilvum_PYR-GCK LPD-----
MSMEG_6807|M.smegmatis_MC2_155 LPT-----
Mb2534|M.bovis_AF2122/97 AADRCL--
Rv2506|M.tuberculosis_H37Rv AADRCL--
MMAR_3853|M.marinum_M VDVGA---
MUL_3785|M.ulcerans_Agy99 VDVGA---
MAB_0483c|M.abscessus_ATCC_199 IERGLVRT
MAV_5253|M.avium_104 AR------
Mvan_4572|M.vanbaalenii_PYR-1 VVDERQRG
MLBr_00717|M.leprae_Br4923 ARQPPQ--
TH_2855|M.thermoresistible__bu S-------