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MAKETESRPRKRAPRRGRADGELSRARILDAATEIAAERGYEGTSIALVSAKCGLPASSIYWHFKDKDDL IAAVIERSFGGWLTAWQIPEGQSGDETIQGAEQFVGLATQTAKALLDSPDFIRLGLMLALERRPAEPRAR TMFLEVRAQAFGQLIGNFGRFMPGLTEAQIYQLATYAMAGADGLFIAKEIDGDAVNLIEMFELHGRALYD AARRFIEDGATR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1504 | - | - | 100% (222) | transcriptional regulatory protein |
| M. marinum M | MMAR_4699 | - | 6e-08 | 27.01% (137) | transcriptional regulatory protein |
| M. marinum M | MMAR_4304 | - | 6e-08 | 44.44% (72) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0310 | - | 8e-20 | 29.21% (202) | TetR/ACRR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4599 | - | 3e-09 | 32.17% (143) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0302 | - | 5e-20 | 29.21% (202) | TetR/ACRR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00316 | - | 9e-05 | 41.38% (58) | putative TetR/AcrR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0901c | - | 1e-09 | 25.93% (216) | TetR family transcriptional regulator |
| M. avium 104 | MAV_3803 | - | 5e-10 | 40.28% (72) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_0227 | - | 2e-09 | 34.25% (73) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2719 | - | 1e-08 | 42.03% (69) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_3884 | - | 3e-08 | 26.89% (119) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_0594 | - | 7e-73 | 67.16% (204) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1504|M.marinum_M MAKETESRPRKRAPRRGRADGE---LSRARILDAATEIAAERGYEGTSIA
Mvan_0594|M.vanbaalenii_PYR-1 ----MTDQPKR---RRRRADGE---LSRRRILDAATEIAAERGYEGTSIG
Mb0310|M.bovis_AF2122/97 -----MGVPAK----KKQQQGE---RSRESILDATERLMATKGYAATSIS
Rv0302|M.tuberculosis_H37Rv -----MGVPAK----KKQQQGE---RSRESILDATERLMATKGYAATSIS
TH_2719|M.thermoresistible__bu -------MASR-----RAQISE---ESRRLLIAAATELFAEQGFRRTTFA
Mflv_4599|M.gilvum_PYR-GCK ----MNKVVVAG----RTRVGG---ERRERILASATELIAERGYHAVSMA
MSMEG_0227|M.smegmatis_MC2_155 -------MAKS------VAPRG---FARERVLEAALNLFAEHGVNGTSLQ
MAV_3803|M.avium_104 --MSAPTAAPRDRVRHPRRPADSVLVRREAILDAAWAVASAQGFDGVQMR
MAB_0901c|M.abscessus_ATCC_199 ----MTTPRTR-----PSRQVGRPGYDLDSLLAVAVSVFNQRGYDGTSME
MLBr_00316|M.leprae_Br4923 -MSVPRSGLSVQMAQPARPLRADAARNRARILGVAYEAFATEGLS-VPID
MUL_3884|M.ulcerans_Agy99 ---MEVPVVAKRAAADKRQRRERGSINPDDIISGAFELAEQVSIDNLSMP
:: : . :
MMAR_1504|M.marinum_M LVSAKCGLPASSIYWHFKDKDDLIAAVIERSFGGWLTAWQIPEGQSGDET
Mvan_0594|M.vanbaalenii_PYR-1 AVSAKCGLPASSIYWHFKDKDDLIAAVIERSFANWLTVWQLP------DD
Mb0310|M.bovis_AF2122/97 DIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFFAAIPTWDEAHGPVE
Rv0302|M.tuberculosis_H37Rv DIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFFAAIPTWDEAHGPVE
TH_2719|M.thermoresistible__bu DIAERSGISRGSIPWHFGNKDGLLRAVIEDFIAGVIELDASEQ-----TL
Mflv_4599|M.gilvum_PYR-GCK DIGVASGVVGPAIYRHFNSKSDLLAALFERVVDKLLKRATAIVEQSRDEA
MSMEG_0227|M.smegmatis_MC2_155 MIADRLGVSKAAVYYQFHSKDDIVFAVVEPIFGDMRRVLRIAEAMSSPDA
MAV_3803|M.avium_104 AVAAQAGIAASSLYRHFRSKSHLLVTVLAREFERLDTEFDCTTGELAPQA
MAB_0901c|M.abscessus_ATCC_199 HLSTRLGISKSSIYHHVSGKEELLRLAVDRALDALFAATEAPDTTTGPAI
MLBr_00316|M.leprae_Br4923 EIARRAGVGAGTVYRHFPTKEALCAAVIGDRMPHLVDDGYVLLKSAGPGE
MUL_3884|M.ulcerans_Agy99 MLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSKYVFATPYVEGSDWRET
: *: :: . *. :
MMAR_1504|M.marinum_M IQGAEQFV-----------GLATQTAKALLDSPDFIRLGLMLALERRPAE
Mvan_0594|M.vanbaalenii_PYR-1 VMARDRLM-----------EVAMGTAKAVLDSPDFLRLGLMLALERRPVE
Mb0310|M.bovis_AF2122/97 QRSERQLT-----------ELVSLQS----QHPDFLRLFYLLSMER-SQD
Rv0302|M.tuberculosis_H37Rv QRSERQLT-----------ELVSLQS----QHPDFLRLFYLLSMER-SQD
TH_2719|M.thermoresistible__bu SEGLDRIR-----------DYVRRPT---------TRLLITLVAEAVEPD
Mflv_4599|M.gilvum_PYR-GCK EALTLLVS-----------DQVALVMDQRELAMVYYREVHNLSDQHQSRL
MSMEG_0227|M.smegmatis_MC2_155 RR-EAAVS-----------GMVELAVR-----------------HRRVSA
MAV_3803|M.avium_104 RLGRLTTH-----------LHMAWQAN----------------PHLTEAM
MAB_0901c|M.abscessus_ATCC_199 DRLENLVK-----------RSIQVLVQ------ELPYVTLLLRIRGNTAA
MLBr_00316|M.leprae_Br4923 ALFTYLRS-----------LVLHWGAT--------------DRGLVDALA
MUL_3884|M.ulcerans_Agy99 LRNHARLMRKTFMSNPILCDLILIRSALSPKTARLGAQKMERAIANLVEA
MMAR_1504|M.marinum_M PRARTMFLEVRAQAFGQLIGNFGRFM-----PGLTEAQIYQLATYAMAGA
Mvan_0594|M.vanbaalenii_PYR-1 PKARAMFIQVREQAFAALATSIRDLG-----LDLSEEQVRHLSTYAIAGA
Mb0310|M.bovis_AF2122/97 PVVAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALS
Rv0302|M.tuberculosis_H37Rv PAVAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALS
TH_2719|M.thermoresistible__bu SPVHAFYAQLHDTLRKWLSDWIDDKD---IPPGVSRE---NFVTVLIGAV
Mflv_4599|M.gilvum_PYR-GCK RRKQRLYLEEWVHLVGELRPAVDEIELRAMVHGAIGAIQSILHYRGTGLA
MSMEG_0227|M.smegmatis_MC2_155 VFHGDPAIDNLVHSRKDLHEVIERLTAILLGPEPGTACRVMMSMLASGIF
MAV_3803|M.avium_104 VRAFVVADSEAAGAIEHAVAVIEDMLARALGGPTPSAHDRDVASLIADVW
MAB_0901c|M.abscessus_ATCC_199 ERRALARRREFDDIVGNLVEEACNEG------SIRAGVDPALTSRLIFGT
MLBr_00316|M.leprae_Br4923 GAGGIDILGVAPDAEDAFLTILSDLLYAAQYAGTARTDVGVREVKSILVG
MUL_3884|M.ulcerans_Agy99 GLSPEDAFDTYAAVSIHVRGSVVLHRLYEKTQSADSGPRAIEDAMNIDPL
MMAR_1504|M.marinum_M DGLFIAKEIDGDA-----------------VNLIEMFELHGRALYDAARR
Mvan_0594|M.vanbaalenii_PYR-1 DGLFIAKEIGGDT-----------------VDLMALFALHGQALYDTALR
Mb0310|M.bovis_AF2122/97 DGVYFAGHLEPDT-----------------TDVERMYRRLRQALEALIPV
Rv0302|M.tuberculosis_H37Rv DGVYFAGHLEPDT-----------------TDVERMYRRLRQALEALIPV
TH_2719|M.thermoresistible__bu IGVHQQWRVAPHH-----------------VDLDACFAALKQLASGD---
Mflv_4599|M.gilvum_PYR-GCK PEQTSALLVAMGH-----------------AVLGVPASSHQVRGVNTEPS
MSMEG_0227|M.smegmatis_MC2_155 SSAMDPELADIDD-----------------EELHRVLLDCTQRLLNAPVS
MAV_3803|M.avium_104 LANLIAVIGGRID-----------------ADLARERIDRTTRQLVHGTD
MAB_0901c|M.abscessus_ATCC_199 VNSLIEWYRPSRT-----------------LSADEVADAVATMIFDGLRT
MLBr_00316|M.leprae_Br4923 CQAMEAYNSALAE-----------------RVTDVVVDGLRAAR------
MUL_3884|M.ulcerans_Agy99 TTPLLAQVSGKGHRIATPDEANFEYGLDCILDHAGRLIDERAKAAKSAPS
MMAR_1504|M.marinum_M FIEDGATR------------
Mvan_0594|M.vanbaalenii_PYR-1 MIEENNR-------------
Mb0310|M.bovis_AF2122/97 LLEET---------------
Rv0302|M.tuberculosis_H37Rv LLEET---------------
TH_2719|M.thermoresistible__bu --------------------
Mflv_4599|M.gilvum_PYR-GCK CPRPGTPQH-----------
MSMEG_0227|M.smegmatis_MC2_155 S-------------------
MAV_3803|M.avium_104 TTT-----------------
MAB_0901c|M.abscessus_ATCC_199 RSGQH---------------
MLBr_00316|M.leprae_Br4923 --------------------
MUL_3884|M.ulcerans_Agy99 RPRKAAKPPAPRTRAKATTR