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AVAIARPKLEGNIAVGEDRQIGFAEFGAPQGRAVFWFHGTPGARRQIPTEARVYAEHHDVRLIGVDRPGI GSSTPHQYGTVSAFADDLRTIADTLGIDKMAVVGLSGGGPYTLACAAGLPDRVVAAGVLGGVAPTRGPDA ISGGLMDLGRRVAPLLRVGGSPLRLSASVLIRMARPVASPALDVYGLMSPQADRHLLARPEFKAMFLDDL LNGSRKQLAAPFNDVIVFARDWGFRLEDVSVPVRWWHGDHDHIIPFSHGEHVVSRLPNAELFHLPGESHL AGLGRGEEILATLMKIWDEEA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4245 | - | - | 100% (302) | hypothetical protein MMAR_4245 |
| M. marinum M | MMAR_3390 | - | 2e-72 | 45.33% (289) | hydrolase |
| M. marinum M | MMAR_1214 | - | 8e-29 | 31.72% (268) | hypothetical protein MMAR_1214 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1223 | - | 1e-160 | 89.37% (301) | hypothetical protein Mb1223 |
| M. gilvum PYR-GCK | Mflv_3278 | - | 1e-126 | 70.67% (300) | alpha/beta hydrolase fold |
| M. tuberculosis H37Rv | Rv1191 | - | 1e-160 | 89.37% (301) | hypothetical protein Rv1191 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0349c | - | 2e-06 | 24.90% (245) | putative hydrolase, alpha/beta fold |
| M. avium 104 | MAV_1342 | - | 1e-139 | 76.08% (301) | hydrolase, alpha/beta hydrolase fold family protein |
| M. smegmatis MC2 155 | MSMEG_3508 | - | 1e-135 | 74.67% (300) | hydrolase, alpha/beta hydrolase fold family protein |
| M. thermoresistible (build 8) | TH_2940 | - | 5e-71 | 45.99% (287) | PUTATIVE alpha/beta hydrolase fold |
| M. ulcerans Agy99 | MUL_2678 | - | 5e-26 | 30.60% (268) | hypothetical protein MUL_2678 |
| M. vanbaalenii PYR-1 | Mvan_2997 | - | 1e-124 | 70.00% (300) | alpha/beta hydrolase fold |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3278|M.gilvum_PYR-GCK --MAVEIARPKLEGNILVGTDRRLGFAEFGDPQGRAIFWLHGTPGARRQV
Mvan_2997|M.vanbaalenii_PYR-1 --MAVDIARPKLEGKVLVDTDRQLGFAEFGDPQGRAIFWLHGTPGARRQI
Mb1223|M.bovis_AF2122/97 --MAVAIARPKLEGNIAVGEDRRIGFAEFGAPQGRAVFWLHGTPGARRQI
Rv1191|M.tuberculosis_H37Rv --MAVAIARPKLEGNIAVGEDRRIGFAEFGAPQGRAVFWLHGTPGARRQI
MMAR_4245|M.marinum_M --MAVAIARPKLEGNIAVGEDRQIGFAEFGAPQGRAVFWFHGTPGARRQI
MAV_1342|M.avium_104 --MAIEIARPKLEGNVAVGEDRQIGFAEFGDPQGRAMFWLHGTPGARRQI
MSMEG_3508|M.smegmatis_MC2_155 MAMVIPIDRPKLEGNVAVGDDRRLGFAEFGDPQGRAIFWLHGTPGARRQI
TH_2940|M.thermoresistible__bu ---VPPTEKPRAEGRVHLPTGRRLGFAEFGDPAGVPVVWLHGTPGGRRQF
MUL_2678|M.ulcerans_Agy99 MQTLPEDIRADEANVVTLPDGRELACLEWGDPTGYPTFYFHGTLSSRLEG
MAB_0349c|M.abscessus_ATCC_199 --MGSAALQDRYLQSCLGGLHVRIG------GEGPVILFWPSLLMTGSMW
: .:. * .: .
Mflv_3278|M.gilvum_PYR-GCK PVEARIFAEKNGIRLIGVDRPGIG-SSTPHEYSKVIDFADDLRTVADTLG
Mvan_2997|M.vanbaalenii_PYR-1 PVEARVFAERNSIRLIGVDRPGIG-SSTPHEYEKVIDFADDLRTVADTLG
Mb1223|M.bovis_AF2122/97 PTEARVYAEHHNIRLIGVDRPGIG-ASTPHQYETILAFADDLRTIADTLG
Rv1191|M.tuberculosis_H37Rv PTEARVYAEHHNIRLIGVDRPGIG-ASTPHQYETILAFADDLRTIADTLG
MMAR_4245|M.marinum_M PTEARVYAEHHDVRLIGVDRPGIG-SSTPHQYGTVSAFADDLRTIADTLG
MAV_1342|M.avium_104 PVEARLYAENHKIRLIGLDRPGIG-SSTPHRYQNIRAFGEDLRTIADTLG
MSMEG_3508|M.smegmatis_MC2_155 PTEARAYAEQNGVRLIGVDRPGIG-SSTPHQYECVLDFASDLRTIADTLG
TH_2940|M.thermoresistible__bu PLTGRRAAEQLGLRVVLLERPGAG-LSDPYRYRSVADWVTDVTYVADAIG
MUL_2678|M.ulcerans_Agy99 -AFADGAARRARFRLIAVDRPGYG-RSTFQEGRTLRDWPADVCALADALG
MAB_0349c|M.abscessus_ATCC_199 AAQAEYFADR--YTVILVDPPGHGDSQSLTRMFRFEDCAHAITQILDSLG
. * . :: :: ** * . . . : : *::*
Mflv_3278|M.gilvum_PYR-GCK IHKMQVIGLSGGGPYTLGCAAAMP--DRVVSVGILGGVAPTRGADGIGGG
Mvan_2997|M.vanbaalenii_PYR-1 ISKMQVIGLSGGGPYTLGAAAAMP--DRVVAVGVLGGVAPTRGSDAIGGG
Mb1223|M.bovis_AF2122/97 IDKMAVVGLSGGGPYTLACAAGLP--DRVVAAGVLGGVAPTRGPDAISGG
Rv1191|M.tuberculosis_H37Rv IDKMAVVGLSGGGPYTLACAAGLP--DRVVAAGVLGGVAPTRGPDAISGG
MMAR_4245|M.marinum_M IDKMAVVGLSGGGPYTLACAAGLP--DRVVAAGVLGGVAPTRGPDAISGG
MAV_1342|M.avium_104 IDKMAVIGLSGGGPYALASAAVLP--DRVVAAGILGGVAPFLGDEGITSG
MSMEG_3508|M.smegmatis_MC2_155 IDKLAVIGLSGGGPYTLACAAAMP--DRVVAAGVLGGVAPMVGPDAISSP
TH_2940|M.thermoresistible__bu AERLAVVGLSGGGPYALACGAVAPLAERVRSIAVLGGVTPSVGPDASATG
MUL_2678|M.ulcerans_Agy99 LDKFGVVGHSGAGTHLFACGARIA-LSRLAFIGALGPWGPLATPEIMGS-
MAB_0349c|M.abscessus_ATCC_199 IERAHVVGNSWGG----------------MIGGTFTAMYPHRAG---ASV
: *:* * .* . : *
Mflv_3278|M.gilvum_PYR-GCK VMGHVGLPVAPLLEHVGTPLSFVATGLIRLIKPVAEPALYLYASISPEGD
Mvan_2997|M.vanbaalenii_PYR-1 IMGNIGLPVAPVLERVGTPLSLVATGLIRLIKPVAEPALYLYASISPEGD
Mb1223|M.bovis_AF2122/97 LMR-LGSAVAPLLQVGGTPLRLGASLLIRAARPVASPALDLYGLLSPRAD
Rv1191|M.tuberculosis_H37Rv LMR-LGSAVAPLLQVGGTPLRLGASLLIRAARPVASPALDLYGLLSPRAD
MMAR_4245|M.marinum_M LMD-LGRRVAPLLRVGGSPLRLSASVLIRMARPVASPALDVYGLMSPQAD
MAV_1342|M.avium_104 LMN-LGKRVAPLLKLGGDPLRIGASLVVRAIRPVANPALYLYAAISPEGD
MSMEG_3508|M.smegmatis_MC2_155 LMQ-LGAVVAPVLQVAGGPIRLVASGMIRLIRPVASPALEIYARLSPEGD
TH_2940|M.thermoresistible__bu AIE-LARRFTSLLGTLRGPLATTLAGLVTPVLPFAHFACQAYASISPESD
MUL_2678|M.ulcerans_Agy99 -LNLADRSYARLAQHGPRLFHALFAPLGWCAKYAPGLFTKLITASVPAVD
MAB_0349c|M.abscessus_ATCC_199 LMNATASRASMRQRVEFRLLTEIVRILGRFREPLTTRAVKAFVGPTIMRE
: : : : . :
Mflv_3278|M.gilvum_PYR-GCK RRLLVRPEFKAMFLDDLLNGSRKQLAAPFADVVVFARDWGFRLDEVKVPV
Mvan_2997|M.vanbaalenii_PYR-1 RRLLVRPEFKAMFLDDLLNGSRRQLAAPFADVVVFARDWGFRLDEVKVPV
Mb1223|M.bovis_AF2122/97 RHLLARPEFKAMFLDDLLNGSRKQLAAPFADVIAFARDWGFRLDEVKVPV
Rv1191|M.tuberculosis_H37Rv RHLLARPEFKAMFLDDLLNGSRKQLAAPFADVIAFARDWGFRLDEVKVPV
MMAR_4245|M.marinum_M RHLLARPEFKAMFLDDLLNGSRKQLAAPFNDVIVFARDWGFRLEDVSVPV
MAV_1342|M.avium_104 RRLLTRPEFGAMFLDDLLNGSRKQLAAPFNDIILFTQDWGFRLDQVKVPV
MSMEG_3508|M.smegmatis_MC2_155 RRMLGRPEFKAMFLDDLLNGSRKQLAAPFYDIVVFERDWGFRLDEVTVPV
TH_2940|M.thermoresistible__bu RRVLHDPEMEAMFIDDLVLAARGGLRAIVDDARLFGRDWGFRLADVRAPV
MUL_2678|M.ulcerans_Agy99 KHRMRDKRFVQHFQAVQLEAFRQGSRGAAYEAFLEYRPWEFDPSEVDVPT
MAB_0349c|M.abscessus_ATCC_199 R-----PHVEQSIRAELRDLRVDSVYWAVNSVVPARPDQRELLGRITTPI
: .. : . : .*
Mflv_3278|M.gilvum_PYR-GCK RWWHGDCDHIVPFEHGKHVVALLPDAEFHPLPGESHLGGLGEAEAIMGAM
Mvan_2997|M.vanbaalenii_PYR-1 HWWHGDCDHIVPFAHGKHVAALLPDAQFYPLPGESHLGGLGEAEAIMQSM
Mb1223|M.bovis_AF2122/97 RWWHGDHDHIVPFSHGEHVVSRLPDAKLLHLPGESHLAGLGRGEEILSTL
Rv1191|M.tuberculosis_H37Rv RWWHGDHDHIVPFSHGEHVVSRLPDAKLLHLPGESHLAGLGRGEEILSTL
MMAR_4245|M.marinum_M RWWHGDHDHIIPFSHGEHVVSRLPNAELFHLPGESHLAGLGRGEEILATL
MAV_1342|M.avium_104 RWWHGDSDHIVPFAHGQHVVSLLPDAELFVLPGESHLGGLGRGEEILSTL
MSMEG_3508|M.smegmatis_MC2_155 RWWHGDHDHIVPFAHGQHVVSRLQDAKLTELPYESHLGGLGCAQEIMGTM
TH_2940|M.thermoresistible__bu RWWHGDSDHIVTLTDAQKAVERLPDAELVLRLEESHLGGFAAADEVLTFV
MUL_2678|M.ulcerans_Agy99 HIWLGTHDSFVPREMGEYLERVIPNVELHWAAGKGHFNVEDWDAIFAACA
MAB_0349c|M.abscessus_ATCC_199 LVIAGREDPTFPVAETELMAEAIPGAELVIMENTGHLAALERPEEVNALI
* * .. : : ..:: .*: .
Mflv_3278|M.gilvum_PYR-GCK GELWDGAGQS-
Mvan_2997|M.vanbaalenii_PYR-1 SDLWDAFEKTR
Mb1223|M.bovis_AF2122/97 MQIWDRDLRK-
Rv1191|M.tuberculosis_H37Rv MQIWDRDLRK-
MMAR_4245|M.marinum_M MKIWDEEA---
MAV_1342|M.avium_104 TKIWDEQN---
MSMEG_3508|M.smegmatis_MC2_155 LQIWDETSALT
TH_2940|M.thermoresistible__bu RESL-------
MUL_2678|M.ulcerans_Agy99 ADI--------
MAB_0349c|M.abscessus_ATCC_199 DDFLKRHPIED
.