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VAMVIPIDRPKLEGNVAVGDDRRLGFAEFGDPQGRAIFWLHGTPGARRQIPTEARAYAEQNGVRLIGVDR PGIGSSTPHQYECVLDFASDLRTIADTLGIDKLAVIGLSGGGPYTLACAAAMPDRVVAAGVLGGVAPMVG PDAISSPLMQLGAVVAPVLQVAGGPIRLVASGMIRLIRPVASPALEIYARLSPEGDRRMLGRPEFKAMFL DDLLNGSRKQLAAPFYDIVVFERDWGFRLDEVTVPVRWWHGDHDHIVPFAHGQHVVSRLQDAKLTELPYE SHLGGLGCAQEIMGTMLQIWDETSALT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3508 | - | - | 100% (307) | hydrolase, alpha/beta hydrolase fold family protein |
| M. smegmatis MC2 155 | MSMEG_3289 | - | 1e-08 | 23.90% (251) | gp61 protein |
| M. smegmatis MC2 155 | MSMEG_2681 | - | 3e-08 | 24.56% (285) | proline imino-peptidase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1223 | - | 1e-138 | 77.26% (299) | hypothetical protein Mb1223 |
| M. gilvum PYR-GCK | Mflv_3278 | - | 1e-130 | 73.67% (300) | alpha/beta hydrolase fold |
| M. tuberculosis H37Rv | Rv1191 | - | 1e-138 | 77.26% (299) | hypothetical protein Rv1191 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4522c | - | 6e-07 | 25.64% (273) | epoxide hydrolase EphF |
| M. marinum M | MMAR_4245 | - | 1e-135 | 74.67% (300) | hypothetical protein MMAR_4245 |
| M. avium 104 | MAV_1342 | - | 1e-130 | 73.33% (300) | hydrolase, alpha/beta hydrolase fold family protein |
| M. thermoresistible (build 8) | TH_2940 | - | 1e-77 | 48.63% (292) | PUTATIVE alpha/beta hydrolase fold |
| M. ulcerans Agy99 | MUL_2678 | - | 6e-25 | 30.96% (281) | hypothetical protein MUL_2678 |
| M. vanbaalenii PYR-1 | Mvan_2997 | - | 1e-128 | 73.67% (300) | alpha/beta hydrolase fold |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1223|M.bovis_AF2122/97 --MAVAIARPKLEGNIAVGEDRRIGFAEFGAPQGRAVFWLHGTPGARRQI
Rv1191|M.tuberculosis_H37Rv --MAVAIARPKLEGNIAVGEDRRIGFAEFGAPQGRAVFWLHGTPGARRQI
MMAR_4245|M.marinum_M --MAVAIARPKLEGNIAVGEDRQIGFAEFGAPQGRAVFWFHGTPGARRQI
MAV_1342|M.avium_104 --MAIEIARPKLEGNVAVGEDRQIGFAEFGDPQGRAMFWLHGTPGARRQI
MSMEG_3508|M.smegmatis_MC2_155 MAMVIPIDRPKLEGNVAVGDDRRLGFAEFGDPQGRAIFWLHGTPGARRQI
Mflv_3278|M.gilvum_PYR-GCK --MAVEIARPKLEGNILVGTDRRLGFAEFGDPQGRAIFWLHGTPGARRQV
Mvan_2997|M.vanbaalenii_PYR-1 --MAVDIARPKLEGKVLVDTDRQLGFAEFGDPQGRAIFWLHGTPGARRQI
TH_2940|M.thermoresistible__bu ---VPPTEKPRAEGRVHLPTGRRLGFAEFGDPAGVPVVWLHGTPGGRRQF
MUL_2678|M.ulcerans_Agy99 MQTLPEDIRADEANVVTLPDGRELACLEWGDPTGYPTFYFHGTLSSRLEG
MAB_4522c|M.abscessus_ATCC_199 MTQRSMPVLDGVEHQYVQAGDVKIHVAVAGPQDGRAVVLLHGWPENWWMW
. .: * * . . :**
Mb1223|M.bovis_AF2122/97 PTEARVYAEH-HNIRLIGVDRPGIGASTPHQYETILAFADDLRTIADTLG
Rv1191|M.tuberculosis_H37Rv PTEARVYAEH-HNIRLIGVDRPGIGASTPHQYETILAFADDLRTIADTLG
MMAR_4245|M.marinum_M PTEARVYAEH-HDVRLIGVDRPGIGSSTPHQYGTVSAFADDLRTIADTLG
MAV_1342|M.avium_104 PVEARLYAEN-HKIRLIGLDRPGIGSSTPHRYQNIRAFGEDLRTIADTLG
MSMEG_3508|M.smegmatis_MC2_155 PTEARAYAEQ-NGVRLIGVDRPGIGSSTPHQYECVLDFASDLRTIADTLG
Mflv_3278|M.gilvum_PYR-GCK PVEARIFAEK-NGIRLIGVDRPGIGSSTPHEYSKVIDFADDLRTVADTLG
Mvan_2997|M.vanbaalenii_PYR-1 PVEARVFAER-NSIRLIGVDRPGIGSSTPHEYEKVIDFADDLRTVADTLG
TH_2940|M.thermoresistible__bu PLTGRRAAEQ-LGLRVVLLERPGAGLSDPYRYRSVADWVTDVTYVADAIG
MUL_2678|M.ulcerans_Agy99 -AFADGAARR-ARFRLIAVDRPGYGRSTFQEGRTLRDWPADVCALADALG
MAB_4522c|M.abscessus_ATCC_199 HKVIPALAAAGYRVHAMDLRGAGWSEVAPAGYE-KEQFASDVLAAADALG
* .: : : .* . : *: **::*
Mb1223|M.bovis_AF2122/97 IDKMAVVGLSGGGPYTLACAAGLP--DRVVAAGVLGGVAPTRGPDAISGG
Rv1191|M.tuberculosis_H37Rv IDKMAVVGLSGGGPYTLACAAGLP--DRVVAAGVLGGVAPTRGPDAISGG
MMAR_4245|M.marinum_M IDKMAVVGLSGGGPYTLACAAGLP--DRVVAAGVLGGVAPTRGPDAISGG
MAV_1342|M.avium_104 IDKMAVIGLSGGGPYALASAAVLP--DRVVAAGILGGVAPFLGDEGITSG
MSMEG_3508|M.smegmatis_MC2_155 IDKLAVIGLSGGGPYTLACAAAMP--DRVVAAGVLGGVAPMVGPDAISSP
Mflv_3278|M.gilvum_PYR-GCK IHKMQVIGLSGGGPYTLGCAAAMP--DRVVSVGILGGVAPTRGADGIGGG
Mvan_2997|M.vanbaalenii_PYR-1 ISKMQVIGLSGGGPYTLGAAAAMP--DRVVAVGVLGGVAPTRGSDAIGGG
TH_2940|M.thermoresistible__bu AERLAVVGLSGGGPYALACGAVAPLAERVRSIAVLGGVTPSVGPDASATG
MUL_2678|M.ulcerans_Agy99 LDKFGVVGHSGAGTHLFACGARIA-LSRLAFIGALGPWGPLATPEIMGS-
MAB_4522c|M.abscessus_ATCC_199 LESFDLVGHDWGGWTAQLVALKAQ--SRIRRLVVLN-IPPVWQQPGRVAR
: ::* . .* . .*: *. *
Mb1223|M.bovis_AF2122/97 LMR-LGSAVAPLLQVGGTPLRLGASLLIRAARP--VASPALDLYGLLSPR
Rv1191|M.tuberculosis_H37Rv LMR-LGSAVAPLLQVGGTPLRLGASLLIRAARP--VASPALDLYGLLSPR
MMAR_4245|M.marinum_M LMD-LGRRVAPLLRVGGSPLRLSASVLIRMARP--VASPALDVYGLMSPQ
MAV_1342|M.avium_104 LMN-LGKRVAPLLKLGGDPLRIGASLVVRAIRP--VANPALYLYAAISPE
MSMEG_3508|M.smegmatis_MC2_155 LMQ-LGAVVAPVLQVAGGPIRLVASGMIRLIRP--VASPALEIYARLSPE
Mflv_3278|M.gilvum_PYR-GCK VMGHVGLPVAPLLEHVGTPLSFVATGLIRLIKP--VAEPALYLYASISPE
Mvan_2997|M.vanbaalenii_PYR-1 IMGNIGLPVAPVLERVGTPLSLVATGLIRLIKP--VAEPALYLYASISPE
TH_2940|M.thermoresistible__bu AIE-LARRFTSLLGTLRGPLATTLAGLVTPVLP--FAHFACQAYASISPE
MUL_2678|M.ulcerans_Agy99 -LNLADRSYARLAQHGPRLFHALFAPLGWCAKY--APGLFTKLITASVPA
MAB_4522c|M.abscessus_ATCC_199 YAHKLAYQLVVGAPVVG-PLSHLSPTLWWFIRRSGMPKESVDFFRSCFRD
. : . : .
Mb1223|M.bovis_AF2122/97 ADRHLLARPEFKAMFLDDLLNGSRKQLAAPFADVIAFARDWGFRLDEVKV
Rv1191|M.tuberculosis_H37Rv ADRHLLARPEFKAMFLDDLLNGSRKQLAAPFADVIAFARDWGFRLDEVKV
MMAR_4245|M.marinum_M ADRHLLARPEFKAMFLDDLLNGSRKQLAAPFNDVIVFARDWGFRLEDVSV
MAV_1342|M.avium_104 GDRRLLTRPEFGAMFLDDLLNGSRKQLAAPFNDIILFTQDWGFRLDQVKV
MSMEG_3508|M.smegmatis_MC2_155 GDRRMLGRPEFKAMFLDDLLNGSRKQLAAPFYDIVVFERDWGFRLDEVTV
Mflv_3278|M.gilvum_PYR-GCK GDRRLLVRPEFKAMFLDDLLNGSRKQLAAPFADVVVFARDWGFRLDEVKV
Mvan_2997|M.vanbaalenii_PYR-1 GDRRLLVRPEFKAMFLDDLLNGSRRQLAAPFADVVVFARDWGFRLDEVKV
TH_2940|M.thermoresistible__bu SDRRVLHDPEMEAMFIDDLVLAARGGLRAIVDDARLFGRDWGFRLADVRA
MUL_2678|M.ulcerans_Agy99 VDKHRMRDKRFVQHFQAVQLEAFRQGSRGAAYEAFLEYRPWEFDPSEVDV
MAB_4522c|M.abscessus_ATCC_199 RDRRVAGSKIYRSMVGKEFANLARG----------------PYDDQKLTM
*:: . * : .:
Mb1223|M.bovis_AF2122/97 PVRWWHGDHDHIVPFSHGEHVVSRLPDAKLLHLPGESHLAGLGRGEEILS
Rv1191|M.tuberculosis_H37Rv PVRWWHGDHDHIVPFSHGEHVVSRLPDAKLLHLPGESHLAGLGRGEEILS
MMAR_4245|M.marinum_M PVRWWHGDHDHIIPFSHGEHVVSRLPNAELFHLPGESHLAGLGRGEEILA
MAV_1342|M.avium_104 PVRWWHGDSDHIVPFAHGQHVVSLLPDAELFVLPGESHLGGLGRGEEILS
MSMEG_3508|M.smegmatis_MC2_155 PVRWWHGDHDHIVPFAHGQHVVSRLQDAKLTELPYESHLGGLGCAQEIMG
Mflv_3278|M.gilvum_PYR-GCK PVRWWHGDCDHIVPFEHGKHVVALLPDAEFHPLPGESHLGGLGEAEAIMG
Mvan_2997|M.vanbaalenii_PYR-1 PVHWWHGDCDHIVPFAHGKHVAALLPDAQFYPLPGESHLGGLGEAEAIMQ
TH_2940|M.thermoresistible__bu PVRWWHGDSDHIVTLTDAQKAVERLPDAELVLRLEESHLGGFAAADEVLT
MUL_2678|M.ulcerans_Agy99 PTHIWLGTHDSFVPREMGEYLERVIPNVELHWAAGKGHFNVEDWDAIFAA
MAB_4522c|M.abscessus_ATCC_199 PVRVLFGLDDVAVHPSLLDGFKDHADDLNITEVPNCGHFIVDEQPELVVK
*.: * * : . : :: .*: .
Mb1223|M.bovis_AF2122/97 TLMQIWDRDLRK-
Rv1191|M.tuberculosis_H37Rv TLMQIWDRDLRK-
MMAR_4245|M.marinum_M TLMKIWDEEA---
MAV_1342|M.avium_104 TLTKIWDEQN---
MSMEG_3508|M.smegmatis_MC2_155 TMLQIWDETSALT
Mflv_3278|M.gilvum_PYR-GCK AMGELWDGAGQS-
Mvan_2997|M.vanbaalenii_PYR-1 SMSDLWDAFEKTR
TH_2940|M.thermoresistible__bu FVRESL-------
MUL_2678|M.ulcerans_Agy99 CAADI--------
MAB_4522c|M.abscessus_ATCC_199 WLSEVLAEPAP--
.