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M. thermoresistible (build 8) TH_2940 (-)

annotation: alpha/beta hydrolase fold
coordinates: 4059921 - 4060820
length: 300

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2940--100% (300)alpha/beta hydrolase fold
M. thermoresistible (build 8)TH_3363-8e-0831.51% (146) PUTATIVE alpha/beta hydrolase fold

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1223-2e-6945.49% (288) hypothetical protein Mb1223
M. gilvum PYR-GCKMflv_0111-1e-11062.21% (299) alpha/beta hydrolase fold
M. tuberculosis H37RvRv1191-2e-6945.49% (288) hypothetical protein Rv1191
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0349c-1e-0624.38% (242) putative hydrolase, alpha/beta fold
M. marinum MMMAR_3390-1e-11867.56% (299) hydrolase
M. avium 104MAV_1342-7e-7347.57% (288) hydrolase, alpha/beta hydrolase fold family protein
M. smegmatis MC2 155MSMEG_3508-2e-7748.63% (292) hydrolase, alpha/beta hydrolase fold family protein
M. ulcerans Agy99MUL_2678-2e-2331.32% (265) hypothetical protein MUL_2678
M. vanbaalenii PYR-1Mvan_0797-1e-11162.54% (299) alpha/beta hydrolase fold

CLUSTAL 2.0.9 multiple sequence alignment


Mb1223|M.bovis_AF2122/97            -----------MAVAIARPKLEGNIAVGEDRRIGFAEFGAPQGRAVFWLH
Rv1191|M.tuberculosis_H37Rv         -----------MAVAIARPKLEGNIAVGEDRRIGFAEFGAPQGRAVFWLH
MAV_1342|M.avium_104                -----------MAIEIARPKLEGNVAVGEDRQIGFAEFGDPQGRAMFWLH
MSMEG_3508|M.smegmatis_MC2_155      ---------MAMVIPIDRPKLEGNVAVGDDRRLGFAEFGDPQGRAIFWLH
TH_2940|M.thermoresistible__bu      ------------VPPTEKPRAEGRVHLPTGRRLGFAEFGDPAGVPVVWLH
MMAR_3390|M.marinum_M               MKLSNPLRHPFFVPRVEKPRAEGRFYLPDGRRLGFAEFGDPAGAVVLWFH
Mflv_0111|M.gilvum_PYR-GCK          -MISNPWRHPPGVPRCEAPRAEGTFFLPDGRRLGYAEFGDPTGDVVLWFH
Mvan_0797|M.vanbaalenii_PYR-1       -MLSNPWRHPPGVPRCEPPRAEGAFFLPDGRRIGYAEYGDPSGPVVLWFH
MUL_2678|M.ulcerans_Agy99           ---------MQTLPEDIRADEANVVTLPDGRELACLEWGDPTGYPTFYFH
MAB_0349c|M.abscessus_ATCC_199      ---------------MGSAALQDRYLQSCLGGLHVRIGGE--GPVILFWP
                                                      .   .         :     *   *   .:  

Mb1223|M.bovis_AF2122/97            GTPGARRQIPTEARVYAEHHNIRLIGVDRPGIGAS-TPHQYETILAFADD
Rv1191|M.tuberculosis_H37Rv         GTPGARRQIPTEARVYAEHHNIRLIGVDRPGIGAS-TPHQYETILAFADD
MAV_1342|M.avium_104                GTPGARRQIPVEARLYAENHKIRLIGLDRPGIGSS-TPHRYQNIRAFGED
MSMEG_3508|M.smegmatis_MC2_155      GTPGARRQIPTEARAYAEQNGVRLIGVDRPGIGSS-TPHQYECVLDFASD
TH_2940|M.thermoresistible__bu      GTPGGRRQFPLTGRRAAEQLGLRVVLLERPGAGLS-DPYRYRSVADWVTD
MMAR_3390|M.marinum_M               GTPGARRQFPLLGRRAAEEFGLRVVVVERPGSGLS-DCHAYTAMADWATD
Mflv_0111|M.gilvum_PYR-GCK          GTPGGRRQLPIVGRRAAERLGLRVVLVERAGAGLS-SAHRYDRIGDWADD
Mvan_0797|M.vanbaalenii_PYR-1       GTPGGRRQLPIVGRRAAEKLGLRVVLVERAGSGLS-HRHCYDRVGDWATD
MUL_2678|M.ulcerans_Agy99           GTLSSRLEG-AFADGAARRARFRLIAVDRPGYGRS-TFQEGRTLRDWPAD
MAB_0349c|M.abscessus_ATCC_199      SLLMTGSMWAAQAEYFADR--YTVILVDPPGHGDSQSLTRMFRFEDCAHA
                                    .           .   * .    :: :: .* * *        .      

Mb1223|M.bovis_AF2122/97            LRTIADTLGIDKMAVVGLSGGGPYTLACAAG--LPDRVVAAGVLGGVAPT
Rv1191|M.tuberculosis_H37Rv         LRTIADTLGIDKMAVVGLSGGGPYTLACAAG--LPDRVVAAGVLGGVAPT
MAV_1342|M.avium_104                LRTIADTLGIDKMAVIGLSGGGPYALASAAV--LPDRVVAAGILGGVAPF
MSMEG_3508|M.smegmatis_MC2_155      LRTIADTLGIDKLAVIGLSGGGPYTLACAAA--MPDRVVAAGVLGGVAPM
TH_2940|M.thermoresistible__bu      VTYVADAIGAERLAVVGLSGGGPYALACGAVAPLAERVRSIAVLGGVTPS
MMAR_3390|M.marinum_M               MTAVANALGAERLAVVGLSGGGPYALACGAVAPLASRVATVAVLGGIVPS
Mflv_0111|M.gilvum_PYR-GCK          MAHVADALGADKLGVAGLSGGGPYALACAGMPALRDRVAAVAVLGGVTPS
Mvan_0797|M.vanbaalenii_PYR-1       MAHVADLLGAEKLGVVGLSGGGPFALACAGMPALADRVVAVAVLGGVTPS
MUL_2678|M.ulcerans_Agy99           VCALADALGLDKFGVVGHSGAGTHLFACGAR-IALSRLAFIGALGPWGPL
MAB_0349c|M.abscessus_ATCC_199      ITQILDSLGIERAHVVGNSWGG----------------MIGGTFTAMYPH
                                    :  : : :* ::  * * * .*                   . :    * 

Mb1223|M.bovis_AF2122/97            RGPDAISGGLMRLGSAVAPLLQVGGTPLRLGASLLIRAARPVASPALDLY
Rv1191|M.tuberculosis_H37Rv         RGPDAISGGLMRLGSAVAPLLQVGGTPLRLGASLLIRAARPVASPALDLY
MAV_1342|M.avium_104                LGDEGITSGLMNLGKRVAPLLKLGGDPLRIGASLVVRAIRPVANPALYLY
MSMEG_3508|M.smegmatis_MC2_155      VGPDAISSPLMQLGAVVAPVLQVAGGPIRLVASGMIRLIRPVASPALEIY
TH_2940|M.thermoresistible__bu      VGPDASATGAIELARRFTSLLGTLRGPLATTLAGLVTPVLPFAHFACQAY
MMAR_3390|M.marinum_M               VGPDATADAVTDLARRFTPILSELRRPLAALAAGLL-PLVPVSHYLYRAY
Mflv_0111|M.gilvum_PYR-GCK          VGPDATASGAITLARQLSAVTSALRRPFAAVTAGLLTPVIPLAHLAYSGL
Mvan_0797|M.vanbaalenii_PYR-1       VGPDAACSGAITLSRKFAPVTSAMRRPFAAVTAGLLTPVIPLAHLAYRGL
MUL_2678|M.ulcerans_Agy99           ATPEIMGS-LNLADRSYARLAQHGPRLFHALFAPLGWCAKYAPGLFTKLI
MAB_0349c|M.abscessus_ATCC_199      RAG--ASVLMNATASRASMRQRVEFRLLTEIVRILGRFREPLTTRAVKAF
                                                     :         :      :       .       

Mb1223|M.bovis_AF2122/97            GLLSPRADRHLLARPEFKAMFLDDLLNGSRKQLAAPFADVIAFARDWGFR
Rv1191|M.tuberculosis_H37Rv         GLLSPRADRHLLARPEFKAMFLDDLLNGSRKQLAAPFADVIAFARDWGFR
MAV_1342|M.avium_104                AAISPEGDRRLLTRPEFGAMFLDDLLNGSRKQLAAPFNDIILFTQDWGFR
MSMEG_3508|M.smegmatis_MC2_155      ARLSPEGDRRMLGRPEFKAMFLDDLLNGSRKQLAAPFYDIVVFERDWGFR
TH_2940|M.thermoresistible__bu      ASISPESDRRVLHDPEMEAMFIDDLVLAARGGLRAIVDDARLFGRDWGFR
MMAR_3390|M.marinum_M               ASITPEGDQQVFADPELEAVFLDDIVLVVKSRCQAMIDDLRLFGRDWGFR
Mflv_0111|M.gilvum_PYR-GCK          AAVMPDGDKRVFANPEIEAMFIDDIVQVANGRFQALLDDARLFGVDWGFR
Mvan_0797|M.vanbaalenii_PYR-1       SAAMPEGDKRVFANPEIEAMFIDDIVHAANGGFQALLDDARLFGRDWGFR
MUL_2678|M.ulcerans_Agy99           TASVPAVDKHRMRDKRFVQHFQAVQLEAFRQGSRGAAYEAFLEYRPWEFD
MAB_0349c|M.abscessus_ATCC_199      VGPTIMRER-----PHVEQSIRAELRDLRVDSVYWAVNSVVPARPDQREL
                                           ::      ..   :                 .           

Mb1223|M.bovis_AF2122/97            LDEVKVPVRWWHGDHDHIVPFSHGEHVVSRLPDAKLLHLPGESHLAGLGR
Rv1191|M.tuberculosis_H37Rv         LDEVKVPVRWWHGDHDHIVPFSHGEHVVSRLPDAKLLHLPGESHLAGLGR
MAV_1342|M.avium_104                LDQVKVPVRWWHGDSDHIVPFAHGQHVVSLLPDAELFVLPGESHLGGLGR
MSMEG_3508|M.smegmatis_MC2_155      LDEVTVPVRWWHGDHDHIVPFAHGQHVVSRLQDAKLTELPYESHLGGLGC
TH_2940|M.thermoresistible__bu      LADVRAPVRWWHGDSDHIVTLTDAQKAVERLPDAELVLRLEESHLGGFAA
MMAR_3390|M.marinum_M               LPDVTVPVRWWHGDADPLVPLAAARAAIARLPNAELIARPGESHLGGFAA
Mflv_0111|M.gilvum_PYR-GCK          LADVAVPVRWWHGDADSIISLADAQAAAEHLPDVDLLLMPDESHLGGFAK
Mvan_0797|M.vanbaalenii_PYR-1       LADVKVPVRWWHGDADSIISLADAQAATEHLPDVELLLMPDESHLGGFAK
MUL_2678|M.ulcerans_Agy99           PSEVDVPTHIWLGTHDSFVPREMGEYLERVIPNVELHWAAGKGHFN-VED
MAB_0349c|M.abscessus_ATCC_199      LGRITTPILVIAGREDPTFPVAETELMAEAIPGAELVIMENTGHLAALER
                                       : .*     *  *  ..    .     : ...*      .*:  .  

Mb1223|M.bovis_AF2122/97            GEEILSTLMQIWDRDLRK-----
Rv1191|M.tuberculosis_H37Rv         GEEILSTLMQIWDRDLRK-----
MAV_1342|M.avium_104                GEEILSTLTKIWDEQN-------
MSMEG_3508|M.smegmatis_MC2_155      AQEIMGTMLQIWDETSALT----
TH_2940|M.thermoresistible__bu      ADEVLTFVRESL-----------
MMAR_3390|M.marinum_M               ADEVLQFVRSSL-----------
Mflv_0111|M.gilvum_PYR-GCK          ADDVLAFLAPHLRHDDEQHRRKV
Mvan_0797|M.vanbaalenii_PYR-1       ADDVLDFLHQHLLSG---HRP--
MUL_2678|M.ulcerans_Agy99           WDAIFAACAADI-----------
MAB_0349c|M.abscessus_ATCC_199      PEEVNALIDDFLKRHPIED----
                                     : :