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MAVEIARPKLEGNILVGTDRRLGFAEFGDPQGRAIFWLHGTPGARRQVPVEARIFAEKNGIRLIGVDRPG IGSSTPHEYSKVIDFADDLRTVADTLGIHKMQVIGLSGGGPYTLGCAAAMPDRVVSVGILGGVAPTRGAD GIGGGVMGHVGLPVAPLLEHVGTPLSFVATGLIRLIKPVAEPALYLYASISPEGDRRLLVRPEFKAMFLD DLLNGSRKQLAAPFADVVVFARDWGFRLDEVKVPVRWWHGDCDHIVPFEHGKHVVALLPDAEFHPLPGES HLGGLGEAEAIMGAMGELWDGAGQS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3278 | - | - | 100% (305) | alpha/beta hydrolase fold |
| M. gilvum PYR-GCK | Mflv_0111 | - | 3e-67 | 42.51% (287) | alpha/beta hydrolase fold |
| M. gilvum PYR-GCK | Mflv_3146 | - | 7e-09 | 26.95% (256) | alpha/beta hydrolase fold |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1223 | - | 1e-130 | 73.00% (300) | hypothetical protein Mb1223 |
| M. tuberculosis H37Rv | Rv1191 | - | 1e-130 | 73.00% (300) | hypothetical protein Rv1191 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3878 | - | 1e-06 | 40.98% (61) | lipase/esterase LipG |
| M. marinum M | MMAR_4245 | - | 1e-126 | 70.67% (300) | hypothetical protein MMAR_4245 |
| M. avium 104 | MAV_1342 | - | 1e-128 | 71.67% (300) | hydrolase, alpha/beta hydrolase fold family protein |
| M. smegmatis MC2 155 | MSMEG_3508 | - | 1e-130 | 73.67% (300) | hydrolase, alpha/beta hydrolase fold family protein |
| M. thermoresistible (build 8) | TH_2940 | - | 8e-72 | 47.22% (288) | PUTATIVE alpha/beta hydrolase fold |
| M. ulcerans Agy99 | MUL_2678 | - | 2e-23 | 31.12% (286) | hypothetical protein MUL_2678 |
| M. vanbaalenii PYR-1 | Mvan_2997 | - | 1e-161 | 89.33% (300) | alpha/beta hydrolase fold |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3278|M.gilvum_PYR-GCK --MAVEIARPKLEGNILVGTDRRLGFAEFGDPQGRAIFWLHGTPGARRQV
Mvan_2997|M.vanbaalenii_PYR-1 --MAVDIARPKLEGKVLVDTDRQLGFAEFGDPQGRAIFWLHGTPGARRQI
Mb1223|M.bovis_AF2122/97 --MAVAIARPKLEGNIAVGEDRRIGFAEFGAPQGRAVFWLHGTPGARRQI
Rv1191|M.tuberculosis_H37Rv --MAVAIARPKLEGNIAVGEDRRIGFAEFGAPQGRAVFWLHGTPGARRQI
MMAR_4245|M.marinum_M --MAVAIARPKLEGNIAVGEDRQIGFAEFGAPQGRAVFWFHGTPGARRQI
MAV_1342|M.avium_104 --MAIEIARPKLEGNVAVGEDRQIGFAEFGDPQGRAMFWLHGTPGARRQI
MSMEG_3508|M.smegmatis_MC2_155 MAMVIPIDRPKLEGNVAVGDDRRLGFAEFGDPQGRAIFWLHGTPGARRQI
TH_2940|M.thermoresistible__bu ---VPPTEKPRAEGRVHLPTGRRLGFAEFGDPAGVPVVWLHGTPGGRRQF
MUL_2678|M.ulcerans_Agy99 MQTLPEDIRADEANVVTLPDGRELACLEWGDPTGYPTFYFHGTLSSRLEG
MAB_3878|M.abscessus_ATCC_1997 --MVPLSSEVPTRSGIARNGDVELFYEDLGNPGDPAVVLVMGVAAQLPMW
. . : . .: : * * . . . . *. .
Mflv_3278|M.gilvum_PYR-GCK PVEARIFAEKNGIRLIGVDRPGIGSSTPHEYS------------------
Mvan_2997|M.vanbaalenii_PYR-1 PVEARVFAERNSIRLIGVDRPGIGSSTPHEYE------------------
Mb1223|M.bovis_AF2122/97 PTEARVYAEHHNIRLIGVDRPGIGASTPHQYE------------------
Rv1191|M.tuberculosis_H37Rv PTEARVYAEHHNIRLIGVDRPGIGASTPHQYE------------------
MMAR_4245|M.marinum_M PTEARVYAEHHDVRLIGVDRPGIGSSTPHQYG------------------
MAV_1342|M.avium_104 PVEARLYAENHKIRLIGLDRPGIGSSTPHRYQ------------------
MSMEG_3508|M.smegmatis_MC2_155 PTEARAYAEQNGVRLIGVDRPGIGSSTPHQYE------------------
TH_2940|M.thermoresistible__bu PLTGRRAAEQLGLRVVLLERPGAGLSDPYRYR------------------
MUL_2678|M.ulcerans_Agy99 -AFADGAARRARFRLIAVDRPGYGRSTFQEGR------------------
MAB_3878|M.abscessus_ATCC_1997 PDGFCRQLLDQGYRVIRFDNRDCGLSTKLDGQKAPGSVQRRVVRYALGMG
*:: .:. . * *
Mflv_3278|M.gilvum_PYR-GCK -----KVIDFADDLRTVADTLGIHKMQVIGLSGGGPYTLGCAAAMP--DR
Mvan_2997|M.vanbaalenii_PYR-1 -----KVIDFADDLRTVADTLGISKMQVIGLSGGGPYTLGAAAAMP--DR
Mb1223|M.bovis_AF2122/97 -----TILAFADDLRTIADTLGIDKMAVVGLSGGGPYTLACAAGLP--DR
Rv1191|M.tuberculosis_H37Rv -----TILAFADDLRTIADTLGIDKMAVVGLSGGGPYTLACAAGLP--DR
MMAR_4245|M.marinum_M -----TVSAFADDLRTIADTLGIDKMAVVGLSGGGPYTLACAAGLP--DR
MAV_1342|M.avium_104 -----NIRAFGEDLRTIADTLGIDKMAVIGLSGGGPYALASAAVLP--DR
MSMEG_3508|M.smegmatis_MC2_155 -----CVLDFASDLRTIADTLGIDKLAVIGLSGGGPYTLACAAAMP--DR
TH_2940|M.thermoresistible__bu -----SVADWVTDVTYVADAIGAERLAVVGLSGGGPYALACGAVAPLAER
MUL_2678|M.ulcerans_Agy99 -----TLRDWPADVCALADALGLDKFGVVGHSGAGTHLFACGARIA-LSR
MAB_3878|M.abscessus_ATCC_1997 SKVPYTLIDMAEDVRSLVDHLGLEKVHIAGASMGGMIVQVFAGTYP--ER
: *: :.* :* :. : * * .* .. . .*
Mflv_3278|M.gilvum_PYR-GCK VVSVGILGGVAPTRGADGIGGGVMGHVGLPVAPLLEHVGTPLSFVATGLI
Mvan_2997|M.vanbaalenii_PYR-1 VVAVGVLGGVAPTRGSDAIGGGIMGNIGLPVAPVLERVGTPLSLVATGLI
Mb1223|M.bovis_AF2122/97 VVAAGVLGGVAPTRGPDAISGGLMR-LGSAVAPLLQVGGTPLRLGASLLI
Rv1191|M.tuberculosis_H37Rv VVAAGVLGGVAPTRGPDAISGGLMR-LGSAVAPLLQVGGTPLRLGASLLI
MMAR_4245|M.marinum_M VVAAGVLGGVAPTRGPDAISGGLMD-LGRRVAPLLRVGGSPLRLSASVLI
MAV_1342|M.avium_104 VVAAGILGGVAPFLGDEGITSGLMN-LGKRVAPLLKLGGDPLRIGASLVV
MSMEG_3508|M.smegmatis_MC2_155 VVAAGVLGGVAPMVGPDAISSPLMQ-LGAVVAPVLQVAGGPIRLVASGMI
TH_2940|M.thermoresistible__bu VRSIAVLGGVTPSVGPDASATGAIE-LARRFTSLLGTLRGPLATTLAGLV
MUL_2678|M.ulcerans_Agy99 LAFIGALGPWGPLATPEIMGS--LNLADRSYARLAQHGPRLFHALFAPLG
MAB_3878|M.abscessus_ATCC_1997 VHSVGIIYSAT----------------GRPFSRLP--SWELIKTALNAPG
: . : : : :
Mflv_3278|M.gilvum_PYR-GCK RLIKPVAEPALYLYASISPEGDRRLLVRPEFKAMFLDDLLNGSRKQLAAP
Mvan_2997|M.vanbaalenii_PYR-1 RLIKPVAEPALYLYASISPEGDRRLLVRPEFKAMFLDDLLNGSRRQLAAP
Mb1223|M.bovis_AF2122/97 RAARPVASPALDLYGLLSPRADRHLLARPEFKAMFLDDLLNGSRKQLAAP
Rv1191|M.tuberculosis_H37Rv RAARPVASPALDLYGLLSPRADRHLLARPEFKAMFLDDLLNGSRKQLAAP
MMAR_4245|M.marinum_M RMARPVASPALDVYGLMSPQADRHLLARPEFKAMFLDDLLNGSRKQLAAP
MAV_1342|M.avium_104 RAIRPVANPALYLYAAISPEGDRRLLTRPEFGAMFLDDLLNGSRKQLAAP
MSMEG_3508|M.smegmatis_MC2_155 RLIRPVASPALEIYARLSPEGDRRMLGRPEFKAMFLDDLLNGSRKQLAAP
TH_2940|M.thermoresistible__bu TPVLPFAHFACQAYASISPESDRRVLHDPEMEAMFIDDLVLAARGGLRAI
MUL_2678|M.ulcerans_Agy99 WCAKYAPGLFTKLITASVPAVDKHRMRDKRFVQHFQAVQLEAFRQGSRGA
MAB_3878|M.abscessus_ATCC_1997 KNATAEEWLEFEVNNGIVYNGPDNLPSREQLRQRILDHRARSDYKIGTVR
. .: : .
Mflv_3278|M.gilvum_PYR-GCK FADVVVFARDWGFRLDEVKVPVRWWHGDCDHIVPFEHGKHVVALLPDAEF
Mvan_2997|M.vanbaalenii_PYR-1 FADVVVFARDWGFRLDEVKVPVHWWHGDCDHIVPFAHGKHVAALLPDAQF
Mb1223|M.bovis_AF2122/97 FADVIAFARDWGFRLDEVKVPVRWWHGDHDHIVPFSHGEHVVSRLPDAKL
Rv1191|M.tuberculosis_H37Rv FADVIAFARDWGFRLDEVKVPVRWWHGDHDHIVPFSHGEHVVSRLPDAKL
MMAR_4245|M.marinum_M FNDVIVFARDWGFRLEDVSVPVRWWHGDHDHIIPFSHGEHVVSRLPNAEL
MAV_1342|M.avium_104 FNDIILFTQDWGFRLDQVKVPVRWWHGDSDHIVPFAHGQHVVSLLPDAEL
MSMEG_3508|M.smegmatis_MC2_155 FYDIVVFERDWGFRLDEVTVPVRWWHGDHDHIVPFAHGQHVVSRLQDAKL
TH_2940|M.thermoresistible__bu VDDARLFGRDWGFRLADVRAPVRWWHGDSDHIVTLTDAQKAVERLPDAEL
MUL_2678|M.ulcerans_Agy99 AYEAFLEYRPWEFDPSEVDVPTHIWLGTHDSFVPREMGEYLERVIPNVEL
MAB_3878|M.abscessus_ATCC_1997 QFDAILGTGSLLRFTRAVVAPAVVIHGRNDPLVPYQNGRVVAKNMRNARF
: * .*. * * ::. .. : :..:
Mflv_3278|M.gilvum_PYR-GCK HPLPGESHLGGLGEAEAIMGAMGELWDGAGQS-
Mvan_2997|M.vanbaalenii_PYR-1 YPLPGESHLGGLGEAEAIMQSMSDLWDAFEKTR
Mb1223|M.bovis_AF2122/97 LHLPGESHLAGLGRGEEILSTLMQIWDRDLRK-
Rv1191|M.tuberculosis_H37Rv LHLPGESHLAGLGRGEEILSTLMQIWDRDLRK-
MMAR_4245|M.marinum_M FHLPGESHLAGLGRGEEILATLMKIWDEEA---
MAV_1342|M.avium_104 FVLPGESHLGGLGRGEEILSTLTKIWDEQN---
MSMEG_3508|M.smegmatis_MC2_155 TELPYESHLGGLGCAQEIMGTMLQIWDETSALT
TH_2940|M.thermoresistible__bu VLRLEESHLGGFAAADEVLTFVRESL-------
MUL_2678|M.ulcerans_Agy99 HWAAGKGHFNVEDWDAIFAACAADI--------
MAB_3878|M.abscessus_ATCC_1997 ALIERMGHDLPEPVWKPVTSELLTTFECAVQD-
.* .