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MAIEIARPKLEGNVAVGEDRQIGFAEFGDPQGRAMFWLHGTPGARRQIPVEARLYAENHKIRLIGLDRPG IGSSTPHRYQNIRAFGEDLRTIADTLGIDKMAVIGLSGGGPYALASAAVLPDRVVAAGILGGVAPFLGDE GITSGLMNLGKRVAPLLKLGGDPLRIGASLVVRAIRPVANPALYLYAAISPEGDRRLLTRPEFGAMFLDD LLNGSRKQLAAPFNDIILFTQDWGFRLDQVKVPVRWWHGDSDHIVPFAHGQHVVSLLPDAELFVLPGESH LGGLGRGEEILSTLTKIWDEQN
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1342 | - | - | 100% (302) | hydrolase, alpha/beta hydrolase fold family protein |
| M. avium 104 | MAV_4371 | - | 2e-06 | 23.02% (252) | hydrolase, alpha/beta fold family protein |
| M. avium 104 | MAV_2517 | - | 4e-06 | 28.31% (272) | 2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1223 | - | 1e-138 | 77.93% (299) | hypothetical protein Mb1223 |
| M. gilvum PYR-GCK | Mflv_3278 | - | 1e-128 | 71.67% (300) | alpha/beta hydrolase fold |
| M. tuberculosis H37Rv | Rv1191 | - | 1e-138 | 77.93% (299) | hypothetical protein Rv1191 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3810 | - | 2e-06 | 23.08% (260) | putative hydrolase, alpha/beta fold |
| M. marinum M | MMAR_4245 | - | 1e-139 | 76.08% (301) | hypothetical protein MMAR_4245 |
| M. smegmatis MC2 155 | MSMEG_3508 | - | 1e-130 | 73.33% (300) | hydrolase, alpha/beta hydrolase fold family protein |
| M. thermoresistible (build 8) | TH_2940 | - | 6e-73 | 47.57% (288) | PUTATIVE alpha/beta hydrolase fold |
| M. ulcerans Agy99 | MUL_2678 | - | 8e-22 | 29.63% (270) | hypothetical protein MUL_2678 |
| M. vanbaalenii PYR-1 | Mvan_2997 | - | 1e-127 | 70.33% (300) | alpha/beta hydrolase fold |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3278|M.gilvum_PYR-GCK --MAVEIARPKLEGNILVGTDRRLGFAEFGDP-QGRAIFWLHGT-PGARR
Mvan_2997|M.vanbaalenii_PYR-1 --MAVDIARPKLEGKVLVDTDRQLGFAEFGDP-QGRAIFWLHGT-PGARR
Mb1223|M.bovis_AF2122/97 --MAVAIARPKLEGNIAVGEDRRIGFAEFGAP-QGRAVFWLHGT-PGARR
Rv1191|M.tuberculosis_H37Rv --MAVAIARPKLEGNIAVGEDRRIGFAEFGAP-QGRAVFWLHGT-PGARR
MMAR_4245|M.marinum_M --MAVAIARPKLEGNIAVGEDRQIGFAEFGAP-QGRAVFWFHGT-PGARR
MAV_1342|M.avium_104 --MAIEIARPKLEGNVAVGEDRQIGFAEFGDP-QGRAMFWLHGT-PGARR
MSMEG_3508|M.smegmatis_MC2_155 MAMVIPIDRPKLEGNVAVGDDRRLGFAEFGDP-QGRAIFWLHGT-PGARR
TH_2940|M.thermoresistible__bu ---VPPTEKPRAEGRVHLPTGRRLGFAEFGDP-AGVPVVWLHGT-PGGRR
MUL_2678|M.ulcerans_Agy99 MQTLPEDIRADEANVVTLPDGRELACLEWGDP-TGYPTFYFHGT-LSSRL
MAB_3810|M.abscessus_ATCC_1997 ----MDVTYEGTKRELATDEG-TLRYHEAGTAGEGEPLILLHGSGPGVTG
: . : * * . * . . :**: .
Mflv_3278|M.gilvum_PYR-GCK QVPVEARIFAEKNGIRLIGVDRPGIGSSTPHEYSKVIDFADDLRTVADTL
Mvan_2997|M.vanbaalenii_PYR-1 QIPVEARVFAERNSIRLIGVDRPGIGSSTPHEYEKVIDFADDLRTVADTL
Mb1223|M.bovis_AF2122/97 QIPTEARVYAEHHNIRLIGVDRPGIGASTPHQYETILAFADDLRTIADTL
Rv1191|M.tuberculosis_H37Rv QIPTEARVYAEHHNIRLIGVDRPGIGASTPHQYETILAFADDLRTIADTL
MMAR_4245|M.marinum_M QIPTEARVYAEHHDVRLIGVDRPGIGSSTPHQYGTVSAFADDLRTIADTL
MAV_1342|M.avium_104 QIPVEARLYAENHKIRLIGLDRPGIGSSTPHRYQNIRAFGEDLRTIADTL
MSMEG_3508|M.smegmatis_MC2_155 QIPTEARAYAEQNGVRLIGVDRPGIGSSTPHQYECVLDFASDLRTIADTL
TH_2940|M.thermoresistible__bu QFPLTGRRAAEQLGLRVVLLERPGAGLSDPYRYRSVADWVTDVTYVADAI
MUL_2678|M.ulcerans_Agy99 EG-AFADGAARRARFRLIAVDRPGYGRSTFQEGRTLRDWPADVCALADAL
MAB_3810|M.abscessus_ATCC_1997 WRNYRGNLGVFAKHFHTYVLEFPGFGVSDAVPGHPVLTAGASVIRFMDGL
. . .: :: ** * * : .: . * :
Mflv_3278|M.gilvum_PYR-GCK GIHKMQVIGLSGGGPYTLGCAAAMP--DRVVSVGILGGVAPTRGADGIGG
Mvan_2997|M.vanbaalenii_PYR-1 GISKMQVIGLSGGGPYTLGAAAAMP--DRVVAVGVLGGVAPTRGSDAIGG
Mb1223|M.bovis_AF2122/97 GIDKMAVVGLSGGGPYTLACAAGLP--DRVVAAGVLGGVAPTRGPDAISG
Rv1191|M.tuberculosis_H37Rv GIDKMAVVGLSGGGPYTLACAAGLP--DRVVAAGVLGGVAPTRGPDAISG
MMAR_4245|M.marinum_M GIDKMAVVGLSGGGPYTLACAAGLP--DRVVAAGVLGGVAPTRGPDAISG
MAV_1342|M.avium_104 GIDKMAVIGLSGGGPYALASAAVLP--DRVVAAGILGGVAPFLGDEGITS
MSMEG_3508|M.smegmatis_MC2_155 GIDKLAVIGLSGGGPYTLACAAAMP--DRVVAAGVLGGVAPMVGPDAISS
TH_2940|M.thermoresistible__bu GAERLAVVGLSGGGPYALACGAVAPLAERVRSIAVLGGVTPSVGPDASAT
MUL_2678|M.ulcerans_Agy99 GLDKFGVVGHSGAGTHLFACGARIA-LSRLAFIGALGPWGPLATPEIMGS
MAB_3810|M.abscessus_ATCC_1997 GISSAAVVGNSMGGVVGINLAIKHP--DRITKLVTIGGVGPNIFSPSPSE
* *:* * .* : . . .*: :* *
Mflv_3278|M.gilvum_PYR-GCK GVMGHVGLPVAPLLEHVGTPLSFVATGLIRLIKPVAEPALYLYASISPEG
Mvan_2997|M.vanbaalenii_PYR-1 GIMGNIGLPVAPVLERVGTPLSLVATGLIRLIKPVAEPALYLYASISPEG
Mb1223|M.bovis_AF2122/97 GLMR-LGSAVAPLLQVGGTPLRLGASLLIRAARPVASPALDLYGLLSPRA
Rv1191|M.tuberculosis_H37Rv GLMR-LGSAVAPLLQVGGTPLRLGASLLIRAARPVASPALDLYGLLSPRA
MMAR_4245|M.marinum_M GLMD-LGRRVAPLLRVGGSPLRLSASVLIRMARPVASPALDVYGLMSPQA
MAV_1342|M.avium_104 GLMN-LGKRVAPLLKLGGDPLRIGASLVVRAIRPVANPALYLYAAISPEG
MSMEG_3508|M.smegmatis_MC2_155 PLMQ-LGAVVAPVLQVAGGPIRLVASGMIRLIRPVASPALEIYARLSPEG
TH_2940|M.thermoresistible__bu GAIE-LARRFTSLLGTLRGPLATTLAGLVTPVLPFAHFACQAYASISPES
MUL_2678|M.ulcerans_Agy99 --LNLADRSYARLAQHGPRLFHALFAPLGWCAKYAPGLFTKLITASVPAV
MAB_3810|M.abscessus_ATCC_1997 G--------LRLLQEFTDNPDRD------KLIRWLNSMVWDPAVVTDELI
:
Mflv_3278|M.gilvum_PYR-GCK DRRLLVRPEFKAMFLDDLLNGSRKQLAAPFADVVVFARDWGFRLDEVKVP
Mvan_2997|M.vanbaalenii_PYR-1 DRRLLVRPEFKAMFLDDLLNGSRRQLAAPFADVVVFARDWGFRLDEVKVP
Mb1223|M.bovis_AF2122/97 DRHLLARPEFKAMFLDDLLNGSRKQLAAPFADVIAFARDWGFRLDEVKVP
Rv1191|M.tuberculosis_H37Rv DRHLLARPEFKAMFLDDLLNGSRKQLAAPFADVIAFARDWGFRLDEVKVP
MMAR_4245|M.marinum_M DRHLLARPEFKAMFLDDLLNGSRKQLAAPFNDVIVFARDWGFRLEDVSVP
MAV_1342|M.avium_104 DRRLLTRPEFGAMFLDDLLNGSRKQLAAPFNDIILFTQDWGFRLDQVKVP
MSMEG_3508|M.smegmatis_MC2_155 DRRMLGRPEFKAMFLDDLLNGSRKQLAAPFYDIVVFERDWGFRLDEVTVP
TH_2940|M.thermoresistible__bu DRRVLHDPEMEAMFIDDLVLAARGGLRAIVDDARLFGRDWGFRLADVRAP
MUL_2678|M.ulcerans_Agy99 DKHRMRDKRFVQHFQAVQLEAFRQGSRGAAYEAFLEYRPWEFDPSEVDVP
MAB_3810|M.abscessus_ATCC_1997 EERWEAAINPDAHKTAQLMYGSKAFAMQQQFLANADIPPYWAMMHKIKCP
:.: . : . : : .: *
Mflv_3278|M.gilvum_PYR-GCK VRWWHGDCDHIVPFEHGKHVVALLPDAEFHPLPGESHLGGLGEAEAIMGA
Mvan_2997|M.vanbaalenii_PYR-1 VHWWHGDCDHIVPFAHGKHVAALLPDAQFYPLPGESHLGGLGEAEAIMQS
Mb1223|M.bovis_AF2122/97 VRWWHGDHDHIVPFSHGEHVVSRLPDAKLLHLPGESHLAGLGRGEEILST
Rv1191|M.tuberculosis_H37Rv VRWWHGDHDHIVPFSHGEHVVSRLPDAKLLHLPGESHLAGLGRGEEILST
MMAR_4245|M.marinum_M VRWWHGDHDHIIPFSHGEHVVSRLPNAELFHLPGESHLAGLGRGEEILAT
MAV_1342|M.avium_104 VRWWHGDSDHIVPFAHGQHVVSLLPDAELFVLPGESHLGGLGRGEEILST
MSMEG_3508|M.smegmatis_MC2_155 VRWWHGDHDHIVPFAHGQHVVSRLQDAKLTELPYESHLGGLGCAQEIMGT
TH_2940|M.thermoresistible__bu VRWWHGDSDHIVTLTDAQKAVERLPDAELVLRLEESHLGGFAAADEVLTF
MUL_2678|M.ulcerans_Agy99 THIWLGTHDSFVPREMGEYLERVIPNVELHWAAGKGHFNVEDWDAIFAAC
MAB_3810|M.abscessus_ATCC_1997 TLLTWGRDDRVSPPDMAIVPMRLIPNAELHIFPNSGHWVMIEAKQAFEQT
. * * . . . : :.:: ..* .
Mflv_3278|M.gilvum_PYR-GCK MGELWDGAGQS-
Mvan_2997|M.vanbaalenii_PYR-1 MSDLWDAFEKTR
Mb1223|M.bovis_AF2122/97 LMQIWDRDLRK-
Rv1191|M.tuberculosis_H37Rv LMQIWDRDLRK-
MMAR_4245|M.marinum_M LMKIWDEEA---
MAV_1342|M.avium_104 LTKIWDEQN---
MSMEG_3508|M.smegmatis_MC2_155 MLQIWDETSALT
TH_2940|M.thermoresistible__bu VRESL-------
MUL_2678|M.ulcerans_Agy99 AADI--------
MAB_3810|M.abscessus_ATCC_1997 VVDFLRR-----
.