For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MKLSNPLRHPFFVPRVEKPRAEGRFYLPDGRRLGFAEFGDPAGAVVLWFHGTPGARRQFPLLGRRAAEEF GLRVVVVERPGSGLSDCHAYTAMADWATDMTAVANALGAERLAVVGLSGGGPYALACGAVAPLASRVATV AVLGGIVPSVGPDATADAVTDLARRFTPILSELRRPLAALAAGLLPLVPVSHYLYRAYASITPEGDQQVF ADPELEAVFLDDIVLVVKSRCQAMIDDLRLFGRDWGFRLPDVTVPVRWWHGDADPLVPLAAARAAIARLP NAELIARPGESHLGGFAAADEVLQFVRSSL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3390 | - | - | 100% (310) | hydrolase |
| M. marinum M | MMAR_4245 | - | 3e-72 | 45.33% (289) | hypothetical protein MMAR_4245 |
| M. marinum M | MMAR_1214 | - | 7e-25 | 31.73% (271) | hypothetical protein MMAR_1214 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1223 | - | 2e-67 | 43.60% (289) | hypothetical protein Mb1223 |
| M. gilvum PYR-GCK | Mflv_0111 | - | 1e-114 | 63.11% (309) | alpha/beta hydrolase fold |
| M. tuberculosis H37Rv | Rv1191 | - | 2e-67 | 43.60% (289) | hypothetical protein Rv1191 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0349c | - | 2e-09 | 26.97% (241) | putative hydrolase, alpha/beta fold |
| M. avium 104 | MAV_1342 | - | 1e-68 | 42.91% (289) | hydrolase, alpha/beta hydrolase fold family protein |
| M. smegmatis MC2 155 | MSMEG_3508 | - | 7e-76 | 46.37% (289) | hydrolase, alpha/beta hydrolase fold family protein |
| M. thermoresistible (build 8) | TH_2940 | - | 1e-118 | 67.56% (299) | PUTATIVE alpha/beta hydrolase fold |
| M. ulcerans Agy99 | MUL_2678 | - | 1e-22 | 30.74% (270) | hypothetical protein MUL_2678 |
| M. vanbaalenii PYR-1 | Mvan_0797 | - | 1e-115 | 63.11% (309) | alpha/beta hydrolase fold |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1223|M.bovis_AF2122/97 -----------MAVAIARPKLEGNIAVGEDRRIGFAEFGAPQGRAVFWLH
Rv1191|M.tuberculosis_H37Rv -----------MAVAIARPKLEGNIAVGEDRRIGFAEFGAPQGRAVFWLH
MAV_1342|M.avium_104 -----------MAIEIARPKLEGNVAVGEDRQIGFAEFGDPQGRAMFWLH
MSMEG_3508|M.smegmatis_MC2_155 ---------MAMVIPIDRPKLEGNVAVGDDRRLGFAEFGDPQGRAIFWLH
MMAR_3390|M.marinum_M MKLSNPLRHPFFVPRVEKPRAEGRFYLPDGRRLGFAEFGDPAGAVVLWFH
TH_2940|M.thermoresistible__bu ------------VPPTEKPRAEGRVHLPTGRRLGFAEFGDPAGVPVVWLH
Mflv_0111|M.gilvum_PYR-GCK -MISNPWRHPPGVPRCEAPRAEGTFFLPDGRRLGYAEFGDPTGDVVLWFH
Mvan_0797|M.vanbaalenii_PYR-1 -MLSNPWRHPPGVPRCEPPRAEGAFFLPDGRRIGYAEYGDPSGPVVLWFH
MUL_2678|M.ulcerans_Agy99 ---------MQTLPEDIRADEANVVTLPDGRELACLEWGDPTGYPTFYFH
MAB_0349c|M.abscessus_ATCC_199 ---------------MGSAALQDRYLQSCLGGLHVRIGGE--GPVILFWP
. . : * * .:
Mb1223|M.bovis_AF2122/97 GTPGARRQIPTEARVYAEHHNIRLIGVDRPGIGAS-TPHQYETILAFADD
Rv1191|M.tuberculosis_H37Rv GTPGARRQIPTEARVYAEHHNIRLIGVDRPGIGAS-TPHQYETILAFADD
MAV_1342|M.avium_104 GTPGARRQIPVEARLYAENHKIRLIGLDRPGIGSS-TPHRYQNIRAFGED
MSMEG_3508|M.smegmatis_MC2_155 GTPGARRQIPTEARAYAEQNGVRLIGVDRPGIGSS-TPHQYECVLDFASD
MMAR_3390|M.marinum_M GTPGARRQFPLLGRRAAEEFGLRVVVVERPGSGLS-DCHAYTAMADWATD
TH_2940|M.thermoresistible__bu GTPGGRRQFPLTGRRAAEQLGLRVVLLERPGAGLS-DPYRYRSVADWVTD
Mflv_0111|M.gilvum_PYR-GCK GTPGGRRQLPIVGRRAAERLGLRVVLVERAGAGLS-SAHRYDRIGDWADD
Mvan_0797|M.vanbaalenii_PYR-1 GTPGGRRQLPIVGRRAAEKLGLRVVLVERAGSGLS-HRHCYDRVGDWATD
MUL_2678|M.ulcerans_Agy99 GTLSSRLEG-AFADGAARRARFRLIAVDRPGYGRS-TFQEGRTLRDWPAD
MAB_0349c|M.abscessus_ATCC_199 SLLMTGSMWAAQAEYFADR--YTVILVDPPGHGDSQSLTRMFRFEDCAHA
. . * . :: :: .* * * .
Mb1223|M.bovis_AF2122/97 LRTIADTLGIDKMAVVGLSGGGPYTLACAAG--LPDRVVAAGVLGGVAPT
Rv1191|M.tuberculosis_H37Rv LRTIADTLGIDKMAVVGLSGGGPYTLACAAG--LPDRVVAAGVLGGVAPT
MAV_1342|M.avium_104 LRTIADTLGIDKMAVIGLSGGGPYALASAAV--LPDRVVAAGILGGVAPF
MSMEG_3508|M.smegmatis_MC2_155 LRTIADTLGIDKLAVIGLSGGGPYTLACAAA--MPDRVVAAGVLGGVAPM
MMAR_3390|M.marinum_M MTAVANALGAERLAVVGLSGGGPYALACGAVAPLASRVATVAVLGGIVPS
TH_2940|M.thermoresistible__bu VTYVADAIGAERLAVVGLSGGGPYALACGAVAPLAERVRSIAVLGGVTPS
Mflv_0111|M.gilvum_PYR-GCK MAHVADALGADKLGVAGLSGGGPYALACAGMPALRDRVAAVAVLGGVTPS
Mvan_0797|M.vanbaalenii_PYR-1 MAHVADLLGAEKLGVVGLSGGGPFALACAGMPALADRVVAVAVLGGVTPS
MUL_2678|M.ulcerans_Agy99 VCALADALGLDKFGVVGHSGAGTHLFACGAR-IALSRLAFIGALGPWGPL
MAB_0349c|M.abscessus_ATCC_199 ITQILDSLGIERAHVVGNSWGG----------------MIGGTFTAMYPH
: : : :* :: * * * .* . : *
Mb1223|M.bovis_AF2122/97 RGPDAISGGLMRLGSAVAPLLQVGGTPLRLGASLLIRAARPVASPALDLY
Rv1191|M.tuberculosis_H37Rv RGPDAISGGLMRLGSAVAPLLQVGGTPLRLGASLLIRAARPVASPALDLY
MAV_1342|M.avium_104 LGDEGITSGLMNLGKRVAPLLKLGGDPLRIGASLVVRAIRPVANPALYLY
MSMEG_3508|M.smegmatis_MC2_155 VGPDAISSPLMQLGAVVAPVLQVAGGPIRLVASGMIRLIRPVASPALEIY
MMAR_3390|M.marinum_M VGPDATADAVTDLARRFTPILSELRRPLAALAAGLL-PLVPVSHYLYRAY
TH_2940|M.thermoresistible__bu VGPDASATGAIELARRFTSLLGTLRGPLATTLAGLVTPVLPFAHFACQAY
Mflv_0111|M.gilvum_PYR-GCK VGPDATASGAITLARQLSAVTSALRRPFAAVTAGLLTPVIPLAHLAYSGL
Mvan_0797|M.vanbaalenii_PYR-1 VGPDAACSGAITLSRKFAPVTSAMRRPFAAVTAGLLTPVIPLAHLAYRGL
MUL_2678|M.ulcerans_Agy99 ATPEIMGS-LNLADRSYARLAQHGPRLFHALFAPLGWCAKYAPGLFTKLI
MAB_0349c|M.abscessus_ATCC_199 RAG--ASVLMNATASRASMRQRVEFRLLTEIVRILGRFREPLTTRAVKAF
: : : .
Mb1223|M.bovis_AF2122/97 GLLSPRADRHLLARPEFKAMFLDDLLNGSRKQLAAPFADVIAFARDWGFR
Rv1191|M.tuberculosis_H37Rv GLLSPRADRHLLARPEFKAMFLDDLLNGSRKQLAAPFADVIAFARDWGFR
MAV_1342|M.avium_104 AAISPEGDRRLLTRPEFGAMFLDDLLNGSRKQLAAPFNDIILFTQDWGFR
MSMEG_3508|M.smegmatis_MC2_155 ARLSPEGDRRMLGRPEFKAMFLDDLLNGSRKQLAAPFYDIVVFERDWGFR
MMAR_3390|M.marinum_M ASITPEGDQQVFADPELEAVFLDDIVLVVKSRCQAMIDDLRLFGRDWGFR
TH_2940|M.thermoresistible__bu ASISPESDRRVLHDPEMEAMFIDDLVLAARGGLRAIVDDARLFGRDWGFR
Mflv_0111|M.gilvum_PYR-GCK AAVMPDGDKRVFANPEIEAMFIDDIVQVANGRFQALLDDARLFGVDWGFR
Mvan_0797|M.vanbaalenii_PYR-1 SAAMPEGDKRVFANPEIEAMFIDDIVHAANGGFQALLDDARLFGRDWGFR
MUL_2678|M.ulcerans_Agy99 TASVPAVDKHRMRDKRFVQHFQAVQLEAFRQGSRGAAYEAFLEYRPWEFD
MAB_0349c|M.abscessus_ATCC_199 VGPTIMRER-----PHVEQSIRAELRDLRVDSVYWAVNSVVPARPDQREL
:: .. : .
Mb1223|M.bovis_AF2122/97 LDEVKVPVRWWHGDHDHIVPFSHGEHVVSRLPDAKLLHLPGESHLAGLGR
Rv1191|M.tuberculosis_H37Rv LDEVKVPVRWWHGDHDHIVPFSHGEHVVSRLPDAKLLHLPGESHLAGLGR
MAV_1342|M.avium_104 LDQVKVPVRWWHGDSDHIVPFAHGQHVVSLLPDAELFVLPGESHLGGLGR
MSMEG_3508|M.smegmatis_MC2_155 LDEVTVPVRWWHGDHDHIVPFAHGQHVVSRLQDAKLTELPYESHLGGLGC
MMAR_3390|M.marinum_M LPDVTVPVRWWHGDADPLVPLAAARAAIARLPNAELIARPGESHLGGFAA
TH_2940|M.thermoresistible__bu LADVRAPVRWWHGDSDHIVTLTDAQKAVERLPDAELVLRLEESHLGGFAA
Mflv_0111|M.gilvum_PYR-GCK LADVAVPVRWWHGDADSIISLADAQAAAEHLPDVDLLLMPDESHLGGFAK
Mvan_0797|M.vanbaalenii_PYR-1 LADVKVPVRWWHGDADSIISLADAQAATEHLPDVELLLMPDESHLGGFAK
MUL_2678|M.ulcerans_Agy99 PSEVDVPTHIWLGTHDSFVPREMGEYLERVIPNVELHWAAGKGHFN-VED
MAB_0349c|M.abscessus_ATCC_199 LGRITTPILVIAGREDPTFPVAETELMAEAIPGAELVIMENTGHLAALER
: .* * * .. . : ...* .*: .
Mb1223|M.bovis_AF2122/97 GEEILSTLMQIWDRDLRK-----
Rv1191|M.tuberculosis_H37Rv GEEILSTLMQIWDRDLRK-----
MAV_1342|M.avium_104 GEEILSTLTKIWDEQN-------
MSMEG_3508|M.smegmatis_MC2_155 AQEIMGTMLQIWDETSALT----
MMAR_3390|M.marinum_M ADEVLQFVRSSL-----------
TH_2940|M.thermoresistible__bu ADEVLTFVRESL-----------
Mflv_0111|M.gilvum_PYR-GCK ADDVLAFLAPHLRHDDEQHRRKV
Mvan_0797|M.vanbaalenii_PYR-1 ADDVLDFLHQHLLSG---HRP--
MUL_2678|M.ulcerans_Agy99 WDAIFAACAADI-----------
MAB_0349c|M.abscessus_ATCC_199 PEEVNALIDDFLKRHPIED----
: :