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QTLPEDIRADEANVVTLPDGRELACLEWGDPTGYPTFYFHGTLSSRLEGAFADGAARRARFRLIAVDRPG YGRSTFQEGRTLRDWPADVCALADALGLDKFGVVGHSGAGTHLFACGARIALSRLAFIGALGPWGPLATP EIMGSLNLADRSYARLAQHGPRLFHALFAPLGWCAKYAPGLFTKLITASVPAVDKHRMRDKRFVQHFQAV QLEAFRQGSRGAAYEAFLEYRPWEFDPSEVDVPTHIWLGTHDSFVPREMGEYLERVIPNVELHWAAGKGH FNVEDWDAIFAACAADI*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_2678 | - | - | 100% (298) | hypothetical protein MUL_2678 |
| M. ulcerans Agy99 | MUL_2888 | ephB | 3e-05 | 33.75% (80) | epoxide hydrolase EphB |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3340c | - | 1e-138 | 77.03% (296) | hypothetical protein Mb3340c |
| M. gilvum PYR-GCK | Mflv_3278 | - | 3e-23 | 31.12% (286) | alpha/beta hydrolase fold |
| M. tuberculosis H37Rv | Rv3312c | - | 1e-138 | 77.03% (296) | hypothetical protein Rv3312c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_1214 | - | 1e-177 | 98.99% (298) | hypothetical protein MMAR_1214 |
| M. avium 104 | MAV_1342 | - | 9e-22 | 29.63% (270) | hydrolase, alpha/beta hydrolase fold family protein |
| M. smegmatis MC2 155 | MSMEG_3508 | - | 9e-25 | 30.96% (281) | hydrolase, alpha/beta hydrolase fold family protein |
| M. thermoresistible (build 8) | TH_2940 | - | 2e-23 | 31.32% (265) | PUTATIVE alpha/beta hydrolase fold |
| M. vanbaalenii PYR-1 | Mvan_0797 | - | 1e-22 | 30.22% (268) | alpha/beta hydrolase fold |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_1342|M.avium_104 ----------MAIEIARPKLEGNVAVGEDRQIGFAEFGDPQGRAMFWLHG
MSMEG_3508|M.smegmatis_MC2_155 --------MAMVIPIDRPKLEGNVAVGDDRRLGFAEFGDPQGRAIFWLHG
Mflv_3278|M.gilvum_PYR-GCK ----------MAVEIARPKLEGNILVGTDRRLGFAEFGDPQGRAIFWLHG
TH_2940|M.thermoresistible__bu -----------VPPTEKPRAEGRVHLPTGRRLGFAEFGDPAGVPVVWLHG
Mvan_0797|M.vanbaalenii_PYR-1 MLSNPWRHPPGVPRCEPPRAEGAFFLPDGRRIGYAEYGDPSGPVVLWFHG
MUL_2678|M.ulcerans_Agy99 --------MQTLPEDIRADEANVVTLPDGRELACLEWGDPTGYPTFYFHG
MMAR_1214|M.marinum_M --------MQTLPEDIRADEANVVTLPDGRELACLEWGDPTGYPTFYFHG
Mb3340c|M.bovis_AF2122/97 ----MTGPPPSLPERIRTDEADVLMLPDGRALAYLEWGDSTGYPAFYFHG
Rv3312c|M.tuberculosis_H37Rv ----MTGPPPSLPERIRTDEADVLMLPDGRALAYLEWGDSTGYPAFYFHG
. . . : .* :. *:**. * .::**
MAV_1342|M.avium_104 TPGARRQIPVEARLYAENHKIRLIGLDRPGIGSSTPHRYQNIRAFGEDLR
MSMEG_3508|M.smegmatis_MC2_155 TPGARRQIPTEARAYAEQNGVRLIGVDRPGIGSSTPHQYECVLDFASDLR
Mflv_3278|M.gilvum_PYR-GCK TPGARRQVPVEARIFAEKNGIRLIGVDRPGIGSSTPHEYSKVIDFADDLR
TH_2940|M.thermoresistible__bu TPGGRRQFPLTGRRAAEQLGLRVVLLERPGAGLSDPYRYRSVADWVTDVT
Mvan_0797|M.vanbaalenii_PYR-1 TPGGRRQLPIVGRRAAEKLGLRVVLVERAGSGLSHRHCYDRVGDWATDMA
MUL_2678|M.ulcerans_Agy99 TLSSRLEG-AFADGAARRARFRLIAVDRPGYGRSTFQEGRTLRDWPADVC
MMAR_1214|M.marinum_M TPSSRLEG-AFADGAARRARFRLIAVDRPGYGRSTFQEGRTLRDWPADVC
Mb3340c|M.bovis_AF2122/97 TPSSRLEG-AFADGAARRTGFRLIAIDRPGYGRSTFQAGRNFRDWPADVC
Rv3312c|M.tuberculosis_H37Rv TPSSRLEG-AFADGAARRTGFRLIAIDRPGYGRSTFQAGRNFRDWPADVC
* ..* : . *.. .*:: ::*.* * * . : *:
MAV_1342|M.avium_104 TIADTLGIDKMAVIGLSGGGPYALASA--AVLPDRVVAAGILGGVAPFLG
MSMEG_3508|M.smegmatis_MC2_155 TIADTLGIDKLAVIGLSGGGPYTLACA--AAMPDRVVAAGVLGGVAPMVG
Mflv_3278|M.gilvum_PYR-GCK TVADTLGIHKMQVIGLSGGGPYTLGCA--AAMPDRVVSVGILGGVAPTRG
TH_2940|M.thermoresistible__bu YVADAIGAERLAVVGLSGGGPYALACGAVAPLAERVRSIAVLGGVTPSVG
Mvan_0797|M.vanbaalenii_PYR-1 HVADLLGAEKLGVVGLSGGGPFALACAGMPALADRVVAVAVLGGVTPSVG
MUL_2678|M.ulcerans_Agy99 ALADALGLDKFGVVGHSGAGTHLFACG-ARIALSRLAFIGALGPWGPLAT
MMAR_1214|M.marinum_M ALADALGLDKFGVVGHSGAGPHLFACG-ARIAPSRLAFIGALGPWGPLAT
Mb3340c|M.bovis_AF2122/97 ALADAFELEEFGVVGHSGAGPHLFACG-AVIPRTRLAFVGALGPWGPLAT
Rv3312c|M.tuberculosis_H37Rv ALADAFELEEFGVVGHSGAGPHLFACG-AVIPRTRLAFVGALGPWGPLAT
:** : ..: *:* **.*.. :... *: . ** *
MAV_1342|M.avium_104 DEGITSGLM-NLGKRVAPLLKLGGDPLRIGASLVVRAIRPVANPALYLYA
MSMEG_3508|M.smegmatis_MC2_155 PDAISSPLM-QLGAVVAPVLQVAGGPIRLVASGMIRLIRPVASPALEIYA
Mflv_3278|M.gilvum_PYR-GCK ADGIGGGVMGHVGLPVAPLLEHVGTPLSFVATGLIRLIKPVAEPALYLYA
TH_2940|M.thermoresistible__bu PDASATGAI-ELARRFTSLLGTLRGPLATTLAGLVTPVLPFAHFACQAYA
Mvan_0797|M.vanbaalenii_PYR-1 PDAACSGAI-TLSRKFAPVTSAMRRPFAAVTAGLLTPVIPLAHLAYRGLS
MUL_2678|M.ulcerans_Agy99 PEIMG--SLNLADRSYARLAQHGPRLFHALFAPLGWCAKYAPGLFTKLIT
MMAR_1214|M.marinum_M PEIMG--SLNLADRSYARLAQHGPRLFHALFAPLGWCAKYAPGLFTKLIT
Mb3340c|M.bovis_AF2122/97 PDIMR--SLNAADRCYARLARSGPRLFGALFAPLGWCAKYTPGLFSTLLA
Rv3312c|M.tuberculosis_H37Rv PDIMR--SLNAADRCYARLARSGPRLFGALFAPLGWCAKYTPGLFSTLLA
: : : : : : : . :
MAV_1342|M.avium_104 AISPEGDRRLLTRPEFGAMFLDDLLNGSRKQLAAPFNDIILFTQDWGFRL
MSMEG_3508|M.smegmatis_MC2_155 RLSPEGDRRMLGRPEFKAMFLDDLLNGSRKQLAAPFYDIVVFERDWGFRL
Mflv_3278|M.gilvum_PYR-GCK SISPEGDRRLLVRPEFKAMFLDDLLNGSRKQLAAPFADVVVFARDWGFRL
TH_2940|M.thermoresistible__bu SISPESDRRVLHDPEMEAMFIDDLVLAARGGLRAIVDDARLFGRDWGFRL
Mvan_0797|M.vanbaalenii_PYR-1 AAMPEGDKRVFANPEIEAMFIDDIVHAANGGFQALLDDARLFGRDWGFRL
MUL_2678|M.ulcerans_Agy99 ASVPAVDKHRMRDKRFVQHFQAVQLEAFRQGSRGAAYEAFLEYRPWEFDP
MMAR_1214|M.marinum_M ASVPAVDKHRMRDKRFVQHFQAVQLEAFRQGSRGAAYEAFLEYRPWEFDP
Mb3340c|M.bovis_AF2122/97 AAVPAADKHLLSDERFGRHLRAIQLEAFRQGSRGAAYESFLQFRPWGFDL
Rv3312c|M.tuberculosis_H37Rv AAVPAADKHLLSDERFGRHLRAIQLEAFRQGSRGAAYESFLQFRPWGFDL
* *:: : .: : : . . . : : : * *
MAV_1342|M.avium_104 DQVKVPVRWWHGDSDHIVPFAHGQHVVSLLPDAELFVLPGESHLGGLGRG
MSMEG_3508|M.smegmatis_MC2_155 DEVTVPVRWWHGDHDHIVPFAHGQHVVSRLQDAKLTELPYESHLGGLGCA
Mflv_3278|M.gilvum_PYR-GCK DEVKVPVRWWHGDCDHIVPFEHGKHVVALLPDAEFHPLPGESHLGGLGEA
TH_2940|M.thermoresistible__bu ADVRAPVRWWHGDSDHIVTLTDAQKAVERLPDAELVLRLEESHLGGFAAA
Mvan_0797|M.vanbaalenii_PYR-1 ADVKVPVRWWHGDADSIISLADAQAATEHLPDVELLLMPDESHLGGFAKA
MUL_2678|M.ulcerans_Agy99 SEVDVPTHIWLGTHDSFVPREMGEYLERVIPNVELHWAAGKGHFN-VEDW
MMAR_1214|M.marinum_M SEVDVPTHIWLGTHDSFVPREMGEYLERVIPNVELHWAAGKGHFN-VEDW
Mb3340c|M.bovis_AF2122/97 AEVAVPTHIWLGDRDSFVPRAMGEYLQRAIPHVDLHWAHGKGHFN-IEDW
Rv3312c|M.tuberculosis_H37Rv AEVAVPTHIWLGDRDSFVPRAMGEYLQRAIPHVDLHWAHGKGHFN-IEDW
:* .*.: * * * ::. .: : ...: :.*:. .
MAV_1342|M.avium_104 EEILSTLTKIWDEQN---
MSMEG_3508|M.smegmatis_MC2_155 QEIMGTMLQIWDETSALT
Mflv_3278|M.gilvum_PYR-GCK EAIMGAMGELWDGAGQS-
TH_2940|M.thermoresistible__bu DEVLTFVRESL-------
Mvan_0797|M.vanbaalenii_PYR-1 DDVLDFLHQHLLSGHRP-
MUL_2678|M.ulcerans_Agy99 DAIFAACAADI-------
MMAR_1214|M.marinum_M DAIFAACAADI-------
Mb3340c|M.bovis_AF2122/97 DAILAACALDIGKRRGG-
Rv3312c|M.tuberculosis_H37Rv DAILAACALDIGKRRGG-
: ::