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MQTLPEDIRADEANVVTLPDGRELACLEWGDPTGYPTFYFHGTPSSRLEGAFADGAARRARFRLIAVDRP GYGRSTFQEGRTLRDWPADVCALADALGLDKFGVVGHSGAGPHLFACGARIAPSRLAFIGALGPWGPLAT PEIMGSLNLADRSYARLAQHGPRLFHALFAPLGWCAKYAPGLFTKLITASVPAVDKHRMRDKRFVQHFQA VQLEAFRQGSRGAAYEAFLEYRPWEFDPSEVDVPTHIWLGTHDSFVPREMGEYLERVIPNVELHWAAGKG HFNVEDWDAIFAACAADI
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1214 | - | - | 100% (298) | hypothetical protein MMAR_1214 |
| M. marinum M | MMAR_4245 | - | 7e-29 | 31.72% (268) | hypothetical protein MMAR_4245 |
| M. marinum M | MMAR_3390 | - | 6e-25 | 31.73% (271) | hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3340c | - | 1e-140 | 77.70% (296) | hypothetical protein Mb3340c |
| M. gilvum PYR-GCK | Mflv_3278 | - | 3e-26 | 32.17% (286) | alpha/beta hydrolase fold |
| M. tuberculosis H37Rv | Rv3312c | - | 1e-140 | 77.70% (296) | hypothetical protein Rv3312c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3556 | - | 2e-06 | 30.51% (118) | putative hydrolase, alpha/beta fold |
| M. avium 104 | MAV_1342 | - | 5e-25 | 30.74% (270) | hydrolase, alpha/beta hydrolase fold family protein |
| M. smegmatis MC2 155 | MSMEG_3508 | - | 8e-28 | 32.03% (281) | hydrolase, alpha/beta hydrolase fold family protein |
| M. thermoresistible (build 8) | TH_2940 | - | 1e-25 | 32.33% (266) | PUTATIVE alpha/beta hydrolase fold |
| M. ulcerans Agy99 | MUL_2678 | - | 1e-177 | 98.99% (298) | hypothetical protein MUL_2678 |
| M. vanbaalenii PYR-1 | Mvan_2997 | - | 1e-24 | 30.50% (282) | alpha/beta hydrolase fold |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1214|M.marinum_M ----MQTLPEDIRADEANVVTLPDGRELACLEWGDPTGYPTFYFHGTPSS
MUL_2678|M.ulcerans_Agy99 ----MQTLPEDIRADEANVVTLPDGRELACLEWGDPTGYPTFYFHGTLSS
Mb3340c|M.bovis_AF2122/97 MTGPPPSLPERIRTDEADVLMLPDGRALAYLEWGDSTGYPAFYFHGTPSS
Rv3312c|M.tuberculosis_H37Rv MTGPPPSLPERIRTDEADVLMLPDGRALAYLEWGDSTGYPAFYFHGTPSS
Mflv_3278|M.gilvum_PYR-GCK ------MAVEIARPKLEGNILVGTDRRLGFAEFGDPQGRAIFWLHGTPGA
Mvan_2997|M.vanbaalenii_PYR-1 ------MAVDIARPKLEGKVLVDTDRQLGFAEFGDPQGRAIFWLHGTPGA
MSMEG_3508|M.smegmatis_MC2_155 ----MAMVIPIDRPKLEGNVAVGDDRRLGFAEFGDPQGRAIFWLHGTPGA
MAV_1342|M.avium_104 ------MAIEIARPKLEGNVAVGEDRQIGFAEFGDPQGRAMFWLHGTPGA
TH_2940|M.thermoresistible__bu -------VPPTEKPRAEGRVHLPTGRRLGFAEFGDPAGVPVVWLHGTPGG
MAB_3556|M.abscessus_ATCC_1997 -----------MGNTLTVQTALLDVEVRRHGNPENTDKLPVVLLHGWPDS
: . : :. . . :** ..
MMAR_1214|M.marinum_M ----RLEG-AFADGAARRARFRLIAVDRPGYGRSTFQEGRTLRDWPADVC
MUL_2678|M.ulcerans_Agy99 ----RLEG-AFADGAARRARFRLIAVDRPGYGRSTFQEGRTLRDWPADVC
Mb3340c|M.bovis_AF2122/97 ----RLEG-AFADGAARRTGFRLIAIDRPGYGRSTFQAGRNFRDWPADVC
Rv3312c|M.tuberculosis_H37Rv ----RLEG-AFADGAARRTGFRLIAIDRPGYGRSTFQAGRNFRDWPADVC
Mflv_3278|M.gilvum_PYR-GCK ----RRQVPVEARIFAEKNGIRLIGVDRPGIGSSTPHEYSKVIDFADDLR
Mvan_2997|M.vanbaalenii_PYR-1 ----RRQIPVEARVFAERNSIRLIGVDRPGIGSSTPHEYEKVIDFADDLR
MSMEG_3508|M.smegmatis_MC2_155 ----RRQIPTEARAYAEQNGVRLIGVDRPGIGSSTPHQYECVLDFASDLR
MAV_1342|M.avium_104 ----RRQIPVEARLYAENHKIRLIGLDRPGIGSSTPHRYQNIRAFGEDLR
TH_2940|M.thermoresistible__bu ----RRQFPLTGRRAAEQLGLRVVLLERPGAGLSDPYRYRSVADWVTDVT
MAB_3556|M.abscessus_ATCC_1997 VATWTHVIPALASAGHQVYAPSVRGTGQTKFRYADTPRTGRLGDLLRDLF
. . : :. : . *:
MMAR_1214|M.marinum_M ALADALGLDKFGVVGHSGAGPHLFACGARIAP-SRLAFIGALGP-WGPLA
MUL_2678|M.ulcerans_Agy99 ALADALGLDKFGVVGHSGAGTHLFACGARIAL-SRLAFIGALGP-WGPLA
Mb3340c|M.bovis_AF2122/97 ALADAFELEEFGVVGHSGAGPHLFACGAVIPR-TRLAFVGALGP-WGPLA
Rv3312c|M.tuberculosis_H37Rv ALADAFELEEFGVVGHSGAGPHLFACGAVIPR-TRLAFVGALGP-WGPLA
Mflv_3278|M.gilvum_PYR-GCK TVADTLGIHKMQVIGLSGGGPYTLGCAAAMP--DRVVSVGILGG-VAPTR
Mvan_2997|M.vanbaalenii_PYR-1 TVADTLGISKMQVIGLSGGGPYTLGAAAAMP--DRVVAVGVLGG-VAPTR
MSMEG_3508|M.smegmatis_MC2_155 TIADTLGIDKLAVIGLSGGGPYTLACAAAMP--DRVVAAGVLGG-VAPMV
MAV_1342|M.avium_104 TIADTLGIDKMAVIGLSGGGPYALASAAVLP--DRVVAAGILGG-VAPFL
TH_2940|M.thermoresistible__bu YVADAIGAERLAVVGLSGGGPYALACGAVAPLAERVRSIAVLGG-VTPSV
MAB_3556|M.abscessus_ATCC_1997 AVCDQLKLERFHLVGHDWGARTAFACGIVAP--HRIASLSAISAGWHPAG
:.* : .: ::* . .. :... . *: . :. *
MMAR_1214|M.marinum_M TPEIMG--SLNLADRSYARLAQHGPRLFHALFAPLGWCAKYAPGLFTKLI
MUL_2678|M.ulcerans_Agy99 TPEIMG--SLNLADRSYARLAQHGPRLFHALFAPLGWCAKYAPGLFTKLI
Mb3340c|M.bovis_AF2122/97 TPDIMR--SLNAADRCYARLARSGPRLFGALFAPLGWCAKYTPGLFSTLL
Rv3312c|M.tuberculosis_H37Rv TPDIMR--SLNAADRCYARLARSGPRLFGALFAPLGWCAKYTPGLFSTLL
Mflv_3278|M.gilvum_PYR-GCK GADGIGGGVMGHVGLPVAPLLEHVGTPLSFVATGLIRLIKPVAEPALYLY
Mvan_2997|M.vanbaalenii_PYR-1 GSDAIGGGIMGNIGLPVAPVLERVGTPLSLVATGLIRLIKPVAEPALYLY
MSMEG_3508|M.smegmatis_MC2_155 GPDAISSPLM-QLGAVVAPVLQVAGGPIRLVASGMIRLIRPVASPALEIY
MAV_1342|M.avium_104 GDEGITSGLM-NLGKRVAPLLKLGGDPLRIGASLVVRAIRPVANPALYLY
TH_2940|M.thermoresistible__bu GPDASATGAI-ELARRFTSLLGTLRGPLATTLAGLVTPVLPFAHFACQAY
MAB_3556|M.abscessus_ATCC_1997 HGPALS--SLQAQRFWYQWLLNTPAG-----ADLLRRERRELVELIWRDW
: : :
MMAR_1214|M.marinum_M TASVPAVDKHRMRDKRFVQHFQAVQLEAFRQGSRGAAYEAFLEYRPWEFD
MUL_2678|M.ulcerans_Agy99 TASVPAVDKHRMRDKRFVQHFQAVQLEAFRQGSRGAAYEAFLEYRPWEFD
Mb3340c|M.bovis_AF2122/97 AAAVPAADKHLLSDERFGRHLRAIQLEAFRQGSRGAAYESFLQFRPWGFD
Rv3312c|M.tuberculosis_H37Rv AAAVPAADKHLLSDERFGRHLRAIQLEAFRQGSRGAAYESFLQFRPWGFD
Mflv_3278|M.gilvum_PYR-GCK ASISPEGDRRLLVRPEFKAMFLDDLLNGSRKQLAAPFADVVVFARDWGFR
Mvan_2997|M.vanbaalenii_PYR-1 ASISPEGDRRLLVRPEFKAMFLDDLLNGSRRQLAAPFADVVVFARDWGFR
MSMEG_3508|M.smegmatis_MC2_155 ARLSPEGDRRMLGRPEFKAMFLDDLLNGSRKQLAAPFYDIVVFERDWGFR
MAV_1342|M.avium_104 AAISPEGDRRLLTRPEFGAMFLDDLLNGSRKQLAAPFNDIILFTQDWGFR
TH_2940|M.thermoresistible__bu ASISPESDRRVLHDPEMEAMFIDDLVLAARGGLRAIVDDARLFGRDWGFR
MAB_3556|M.abscessus_ATCC_1997 SPNWKFSDQ--EFDDTFTSLQSSDWLEVTLSYYRARWGWGPVIDDPFEKQ
: *: : : . : :
MMAR_1214|M.marinum_M PSE---VDVPTHIWLGTHDSFVPREMGEYLERVIPN-VELHWAAGKGHFN
MUL_2678|M.ulcerans_Agy99 PSE---VDVPTHIWLGTHDSFVPREMGEYLERVIPN-VELHWAAGKGHFN
Mb3340c|M.bovis_AF2122/97 LAE---VAVPTHIWLGDRDSFVPRAMGEYLQRAIPH-VDLHWAHGKGHFN
Rv3312c|M.tuberculosis_H37Rv LAE---VAVPTHIWLGDRDSFVPRAMGEYLQRAIPH-VDLHWAHGKGHFN
Mflv_3278|M.gilvum_PYR-GCK LDE---VKVPVRWWHGDCDHIVPFEHGKHVVALLPD-AEFHPLPGESHLG
Mvan_2997|M.vanbaalenii_PYR-1 LDE---VKVPVHWWHGDCDHIVPFAHGKHVAALLPD-AQFYPLPGESHLG
MSMEG_3508|M.smegmatis_MC2_155 LDE---VTVPVRWWHGDHDHIVPFAHGQHVVSRLQD-AKLTELPYESHLG
MAV_1342|M.avium_104 LDQ---VKVPVRWWHGDSDHIVPFAHGQHVVSLLPD-AELFVLPGESHLG
TH_2940|M.thermoresistible__bu LAD---VRAPVRWWHGDSDHIVTLTDAQKAVERLPD-AELVLRLEESHLG
MAB_3556|M.abscessus_ATCC_1997 IAQATAISVPSLVLHGDSDNCVLPIASEGMNQHFPHGFSRLTTPGVGHFP
: : .* * * * .: : . . .*:
MMAR_1214|M.marinum_M -VEDWDAIFAACAADI-------
MUL_2678|M.ulcerans_Agy99 -VEDWDAIFAACAADI-------
Mb3340c|M.bovis_AF2122/97 -IEDWDAILAACALDIGKRRGG-
Rv3312c|M.tuberculosis_H37Rv -IEDWDAILAACALDIGKRRGG-
Mflv_3278|M.gilvum_PYR-GCK GLGEAEAIMGAMGELWDGAGQS-
Mvan_2997|M.vanbaalenii_PYR-1 GLGEAEAIMQSMSDLWDAFEKTR
MSMEG_3508|M.smegmatis_MC2_155 GLGCAQEIMGTMLQIWDETSALT
MAV_1342|M.avium_104 GLGRGEEILSTLTKIWDEQN---
TH_2940|M.thermoresistible__bu GFAAADEVLTFVRESL-------
MAB_3556|M.abscessus_ATCC_1997 QREDPLWVSGALLQWFKEWGNAR
: