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MAVSTDRPAARESEHTGIARWIRRLAIPIILGWIALLGVLGATVPSLEEVGQMRSVSMSPDYAPSVIAMK RVGEVFEEFKSDSSAMIVLEGDEPLGDDAHIFYNDMVDRLEADTEHVEHVQDFWGDPLTEAGAQSNDGRA AYVQVFLAGNMGEALANESVQAVQELVEGLQPPPGVKVYVTGGSALANDQQISGDRSVRIIEAVTFLVII TMLLLVYRSIVTVLITLFLVVICLQSARGVVAFLGYHELIGLSTFATQLLVTLAIAASTDYAIFLIGRYQ EARTLGESKEQAYYTMFRGTAHVVLGSGMTIAGATLCLHFTRLPYFQTLGIPMAVGMTIAVVAALTLGPA VITVMTRFGKILEPKRAMRIRGWRRLGAFVVRWPGAVLMATVLLSLVGLLALPGYRTNYNDRNYLPDDLP AQEGFAAAERHFSPAKMNPELLLIETDHDIRNSADFLVIDKIAKAVFRVPGIGSVQAITRPQGEPLEFST IPAQMSMGGTLQTMNRKYMLDRADDMLLQADEMQRTIELMGRTIELMEEMAATTHSMVGKTHLMVEDVKE LRDNISNFDDFLRPLRNYLYWEPHCYDIPMCHSMRSIFDALDGMDTMTEAMEELLPDMDRLDALMPRMVA LMPPQIETMRKMRTMMLTMHQTQKGLQEQMGAMQEGQTAMGEAFNTAKNDDTFYLPPEIFNNADFKRGMD SFISPDGKAVRFIISHEGDPLTPEGIKLIDQIKLAAKEAMKNTPWEGSKIYVGGTAAAFKDMQEGNNYDL IIAGISALCLIFIIMLLITRSVVAAAVIVGTVLVSLGASFGLSILVWQHILGIDLHFMVMAMAVIVLLAV GADYNLLLVARLKEELPAGINTGIIRAMGGSGSVVTAAGLVFAFTMMSMLVSEMTVVAQVGTTIGMGLLF DTLVIRSFMTPSIAALLGRWFWWPQVVRARPARGVVARALERDKAATH
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_4383 | - | - | 100% (958) | MmpL5 protein |
M. smegmatis MC2 155 | MSMEG_0225 | - | 0.0 | 72.43% (943) | MmpL4 protein |
M. smegmatis MC2 155 | MSMEG_3496 | - | 0.0 | 72.04% (937) | MmpL4 protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0695c | mmpL5 | 0.0 | 69.57% (940) | transmembrane transport protein MmpL5 |
M. gilvum PYR-GCK | Mflv_3435 | - | 0.0 | 71.63% (934) | transport protein |
M. tuberculosis H37Rv | Rv0676c | mmpL5 | 0.0 | 69.47% (940) | transmembrane transport protein MmpL5 |
M. leprae Br4923 | MLBr_02378 | - | 0.0 | 61.08% (930) | hypothetical protein MLBr_02378 |
M. abscessus ATCC 19977 | MAB_2301 | - | 0.0 | 63.33% (938) | putative membrane protein, mmpL |
M. marinum M | MMAR_1005 | mmpL5 | 0.0 | 69.30% (935) | transmembrane transport protein, MmpL5 |
M. avium 104 | MAV_2510 | - | 0.0 | 68.63% (934) | MmpL4 protein |
M. thermoresistible (build 8) | TH_3260 | - | 0.0 | 65.92% (942) | PUTATIVE MmpL4 protein |
M. ulcerans Agy99 | MUL_0757 | mmpL5 | 0.0 | 69.09% (935) | transmembrane transport protein, MmpL5 |
M. vanbaalenii PYR-1 | Mvan_3189 | - | 0.0 | 71.84% (934) | transport protein |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_3435|M.gilvum_PYR-GCK MSAPVSDARTDEFPAAHGPHRS------FIPRMIRLFAVPIILGWIALIV Mvan_3189|M.vanbaalenii_PYR-1 MSAPVSDARTDEFPAARQPHRP------FIPRMIRLFAVPIILGWIALIV TH_3260|M.thermoresistible__bu MTANPGHVRTDEAPTDRLDIKVSTHGPSFISTWIRRLSLPIIVGWIALIA Mb0695c|M.bovis_AF2122/97 MIVQRTAAPTGSVPPDRHAARP------FIPRMIRTFAVPIILGWLVTIA Rv0676c|M.tuberculosis_H37Rv MIVQRTAAPTGSVPPDRHAARP------FIPRMIRTFAVPIILGWLVTIA MMAR_1005|M.marinum_M MTATTTDTPTDVVPPAEHPPRP------FIPRMIRTFAVPLILGWVLLIA MUL_0757|M.ulcerans_Agy99 MTATTTDTPTDVVPPAEHPPRP------FIPRMIRTFAVPLILGWVLLIA MAV_2510|M.avium_104 MSTTFDDTRTDAIPVVKEPVRE------KIPRFIRAFAVPIIIGWIALIA MSMEG_4383|M.smegmatis_MC2_155 ------MAVSTDRPAARESEHTG------IARWIRRLAIPIILGWIALLG MLBr_02378|M.leprae_Br4923 MTVKCANDLDTHTKPP------------FVARMIHRFAVPIILVWLAIAV MAB_2301|M.abscessus_ATCC_1997 MSGSHAG--RSAAEPT------------FLAKWIRRLSIPIVIGWLAIVF :. *: :::*::: *: Mflv_3435|M.gilvum_PYR-GCK VVNVTVPQLETVGEAQAVSMSPNDAPSMISMKKVGELFEEGDSDSSVMIV Mvan_3189|M.vanbaalenii_PYR-1 ILNVTVPQLEAVGEARAVSMSPNEAPSLISMKKVGELFREGDSDSSVMIV TH_3260|M.thermoresistible__bu LLNITVPQLEVVGEMRAVSMSPDEAPSMVAMKRVGELFDEGSSDSQVMIV Mb0695c|M.bovis_AF2122/97 VLNVTVPQLETVGQIQAVSMSPDAAPSMISMKHIGKVFEEGDSDSAAMIV Rv0676c|M.tuberculosis_H37Rv VLNVTVPQLETVGQIQAVSMSPDAAPSMISMKHIGKVFEEGDSDSAAMIV MMAR_1005|M.marinum_M VLNSVVPQLEVVGQMQAVSMSPDAAPSMISMKHIGKVFREGDSDSAAMIV MUL_0757|M.ulcerans_Agy99 VLNSVVPQLEVVGQMQAVSMSPDAAPSMISMKHIGKVFREGDSDSAAMIV MAV_2510|M.avium_104 VLNVVVPQLDEVGKMRSVEMTPDDAQSVVATKRMGAVFNEYKSNSSVMIV MSMEG_4383|M.smegmatis_MC2_155 VLGATVPSLEEVGQMRSVSMSPDYAPSVIAMKRVGEVFEEFKSDSSAMIV MLBr_02378|M.leprae_Br4923 TVSVFIPSLEDVGQERSVSLSPKDAPSYIAMQKMGQVFNEGNSDSVIMIV MAB_2301|M.abscessus_ATCC_1997 ALNTFVPQLEQVGKEHTVSLSPQSAPSMQAMKHMGKMFKESDSDSVVMIV :. :*.*: **: ::*.::*. * * : :::* :* * .*:* *** Mflv_3435|M.gilvum_PYR-GCK FEGDQPLGDEAHAWYDELVDRLEADTAHVQSVQDFWSDPLTASGSQSNDG Mvan_3189|M.vanbaalenii_PYR-1 FEGDQPLGDEAHAWYDELVERLRADTKHVQSVQDFWSDPLTASGSQSNDG TH_3260|M.thermoresistible__bu LEGEEPLGADARAFYDELVKRLEADDAHVENVQDLWSDPLTATGVQSPDG Mb0695c|M.bovis_AF2122/97 LEGQRPLGDAAHAFYDQMIGRLQADTTHVQSLQDFWGDPLTATGAQSSDG Rv0676c|M.tuberculosis_H37Rv LEGQRPLGDAAHAFYDQMIGRLQADTTHVQSLQDFWGDPLTATGAQSSDG MMAR_1005|M.marinum_M LEGQEPLGAAAHKFYDKMITKLRADTKHVQSVQDFWGDPLTATGAQSGDG MUL_0757|M.ulcerans_Agy99 LEGQEPLGAAAHKFYDKMITKLRADTKHVQSVQDFWGDPLTATGAQSGDG MAV_2510|M.avium_104 LEGQQPLGADAHAYYDEIVRRLNADTKHVEHVQDMWSDPLTGAGAQSNDG MSMEG_4383|M.smegmatis_MC2_155 LEGDEPLGDDAHIFYNDMVDRLEADTEHVEHVQDFWGDPLTEAGAQSNDG MLBr_02378|M.leprae_Br4923 LEGDKPLGDDAHRFYDGLIRKLRAD-KHVQSVQDFWGDPLTAPGAQSNDG MAB_2301|M.abscessus_ATCC_1997 LEGQERLGPGSHKFYDEMVARLRADTKHVQHVQDFWGDPLTEAGAQSTDG :**:. ** :: :*: :: :*.** **: :**:*.**** .* ** ** Mflv_3435|M.gilvum_PYR-GCK KAAYVQVKLSGNQGEALANESVKAVQQTVSSLE---------PPPGVRAF Mvan_3189|M.vanbaalenii_PYR-1 KAAYVQVKLAGNQGESLANESVQAAQEIVRSLE---------PPPGVRAF TH_3260|M.thermoresistible__bu KSAYVQVKLAGNQGEALANESVETVREMIATVSEE------MAPEGVQAF Mb0695c|M.bovis_AF2122/97 KAAYVQVKLAGNQGESLANESVEAVKTIVERLA---------PPPGVKVY Rv0676c|M.tuberculosis_H37Rv KAAYVQVKLAGNQGESLANESVEAVKTIVERLA---------PPPGVKVY MMAR_1005|M.marinum_M KAAYVQVKLAGNQGESLANESVEAVKTIVDSLQ---------APPGVKVY MUL_0757|M.ulcerans_Agy99 KAAYVQVKLAGNQGESLANESVEAVKTIVDSLQ---------APPGVKVY MAV_2510|M.avium_104 KASYVQVYLAGNQGEALANESVESVQNIVKSVQ---------APNGVKAY MSMEG_4383|M.smegmatis_MC2_155 RAAYVQVFLAGNMGEALANESVQAVQELVEGLQ---------PPPGVKVY MLBr_02378|M.leprae_Br4923 KAAYVQLSLAGNQGELLAQESIDAVRKIVVQTPA---------PPGITAW MAB_2301|M.abscessus_ATCC_1997 KATYVQVNLAGNMGETLSNESTEAARNIVKQLEADWTKDGNKLPDGLTVY :::***: *:** ** *::** .:.: : * *: .: Mflv_3435|M.gilvum_PYR-GCK VTGPAALAADQHIAGDRSMRLIEAATFTVIIVMLLLVYRSIVTVLITLVM Mvan_3189|M.vanbaalenii_PYR-1 VTGPAALAADQHIASDRSVRVIELVTFAVIIVMLLLVYRSIVTVLLTLVM TH_3260|M.thermoresistible__bu VTGGAAMSADQQEAGDSSLRVIEALTFLVITTMLLFVYRSVITVLIALFM Mb0695c|M.bovis_AF2122/97 VTGSAALVADQQQAGDRSLQVIEAVTFTVIIVMLLLVYRSIITSAIMLTM Rv0676c|M.tuberculosis_H37Rv VTGSAALVADQQQAGDRSLQVIEAVTFTVIIVMLLLVYRSIITSAIMLTM MMAR_1005|M.marinum_M VTGSAALVADQQLAGDRSLQLIEMVTFTVIIVMLLLVYRSIITAAIMLTM MUL_0757|M.ulcerans_Agy99 VTGSAALVADQQLAGDRSLQLIEMVTFTVIIVMLLLVYRSIITAAIMLTM MAV_2510|M.avium_104 VTGPAALSADQHTAGDRSLQLITAATFTVIIGMLLLVYRSVITVLLTLVM MSMEG_4383|M.smegmatis_MC2_155 VTGGSALANDQQISGDRSVRIIEAVTFLVIITMLLLVYRSIVTVLITLFL MLBr_02378|M.leprae_Br4923 VTGASALIADMHHSGDKSMIRITATSVIVILVTLLLVYRSFITVILLLFT MAB_2301|M.abscessus_ATCC_1997 VTGPGALQTDMNHAGDGSLQLITGLTFLVIVVMLLFFYRSIFTVIMVFML *** .*: * : :.* *: * :. ** **:.***..* : : Mflv_3435|M.gilvum_PYR-GCK VVMSLATARGVVAFLGHHEIIGLSTFATNLLVTLAIAAATDYAIFLIGRY Mvan_3189|M.vanbaalenii_PYR-1 VVLSLATARGVVAFLGWHEIIGLSLFATNLLVTLAIAAATDYAIFLIGRY TH_3260|M.thermoresistible__bu VLIGLLTTRGVVAFLGYHNIIGLSTFATSLLVTLAIAIAVDYAIFLIGRY Mb0695c|M.bovis_AF2122/97 VVLGLLATRGGVAFLGFHRIIGLSTFATNLLVVLAIAAATDYAIFLIGRY Rv0676c|M.tuberculosis_H37Rv VVLGLLATRGGVAFLGFHRIIGLSTFATNLLVVLAIAAATDYAIFLIGRY MMAR_1005|M.marinum_M VVLGLLATRGGVAFLGYHRIIGLSTFATNLLVVLAIAAATDYAIFLIGRY MUL_0757|M.ulcerans_Agy99 VVLGLLATRGGVAFLGYHRIIGLSTFATNLLVVLAIAAATDYAIFLIGRY MAV_2510|M.avium_104 VVLELSAARGMVAFLGYYKIIGLSTFATNLLVTLAIAAATDYAIFLIGRY MSMEG_4383|M.smegmatis_MC2_155 VVICLQSARGVVAFLGYHELIGLSTFATQLLVTLAIAASTDYAIFLIGRY MLBr_02378|M.leprae_Br4923 VGIESAVARGVVALLGHTGLIGLSTFAVNLLTSLAIAAGTDYGIFITGRY MAB_2301|M.abscessus_ATCC_1997 VGIQLSAARGVIAFLGNTEIIGLSTFAVNLLVMLSIAAGTDYAIFLIGRY * : :** :*:** :**** **..**. *:** ..**.**: *** Mflv_3435|M.gilvum_PYR-GCK QEARTAGEDKETAYYTMFHGTAHVVLGSGLTIAGATFCLSFTRLPYFQTM Mvan_3189|M.vanbaalenii_PYR-1 QEARTNGEDKESAYYTMFHGTAHVVLGSGLTIAGATYCLSFTRLPYFQTL TH_3260|M.thermoresistible__bu QEARSVGADRATAYHTMFGGTAHVILASGLTIAGATFCLSFTRLPYFQSL Mb0695c|M.bovis_AF2122/97 QEARGLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFTRLPYFQTL Rv0676c|M.tuberculosis_H37Rv QEARGLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFTRLPYFQTL MMAR_1005|M.marinum_M QEARGLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFTRLPYFQTL MUL_0757|M.ulcerans_Agy99 QEARGLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFTRLPYFQTL MAV_2510|M.avium_104 QEARAVGESREDAYYTMYKGTAHVVAGSGMTIAGATFCLHFTNLPYFQTL MSMEG_4383|M.smegmatis_MC2_155 QEARTLGESKEQAYYTMFRGTAHVVLGSGMTIAGATLCLHFTRLPYFQTL MLBr_02378|M.leprae_Br4923 QEARQANENKEAAFYTMYRGTFHVILGSGLTISGATFCLSFARMPYFQTL MAB_2301|M.abscessus_ATCC_1997 QEARAMGADKEAAYYEMFHGTAHVILGSGMTIAGAMYCLSFTRMPYFQTL **** . .: *:: *: ** **: .**:**:** ** *:.:****:: Mflv_3435|M.gilvum_PYR-GCK GVPLAIGMFVVVMAGVVLMVACISVATRFGKLLEPKRAMRIRGWRKIGAA Mvan_3189|M.vanbaalenii_PYR-1 GVPLAIGMFVVVMAGVILMVAMISVATRFGKLLEPKRAMRIRGWRKIGAA TH_3260|M.thermoresistible__bu GPPLAIGMIVLIVTSLTMGPAIITVATRFG-LLEPKRAARVRFWRKVGAS Mb0695c|M.bovis_AF2122/97 GVPLAIGMVIVVAAALTLGPAIIAVTSRFGKLLEPKRMARVRGWRKVGAA Rv0676c|M.tuberculosis_H37Rv GVPLAIGMVIVVAAALTLGPAIIAVTSRFGKLLEPKRMARVRGWRKVGAA MMAR_1005|M.marinum_M GVPLAIGMVIVVATALTLGPALIAVMSRFGKLLEPKRMARVRGWRKIGAA MUL_0757|M.ulcerans_Agy99 GVPLAIGMVIVVATALTLGPALIAVMSRFGKLLEPKRMARVRGWRKIGAA MAV_2510|M.avium_104 GIPLAIGMVVVVAAALTLGPAVISVASRFRQTLEPRRTQRIRGWRKVGTV MSMEG_4383|M.smegmatis_MC2_155 GIPMAVGMTIAVVAALTLGPAVITVMTRFGKILEPKRAMRIRGWRRLGAF MLBr_02378|M.leprae_Br4923 GVPCAVGMLIAVAVALTLGPAVLTVGSRFG-LFEPKRLIKVRGWRRIGTV MAB_2301|M.abscessus_ATCC_1997 GVPCSVGLLVGVLVSLTLGPALITIGSRFG-LFEPKRAMRIRSWRKIGTT * * ::*: : : ..: : * ::: :** :**:* ::* **::*: Mflv_3435|M.gilvum_PYR-GCK IVRWPGPILVATMAITLVGLLALPGYKTNYNDRDYLPADLPANQGYAVAD Mvan_3189|M.vanbaalenii_PYR-1 VVRWPGPILVATLAITLVGLLALPGYKTNYNDRTYLPADLPANEGYAVAD TH_3260|M.thermoresistible__bu VVRWPGPIMVTTVAVTLVGLLALPGYRTNYNDRNYLPASFPSNAGYEAAE Mb0695c|M.bovis_AF2122/97 IVRWPGPILVGAVALALVGLLTLPGYRTNYNDRNYLPADLPANEGYAAAE Rv0676c|M.tuberculosis_H37Rv IVRWPGPILVGAVALALVGLLTLPGYRTNYNDRNYLPADLPANEGYAAAE MMAR_1005|M.marinum_M IVRWPGPILIGAVALALVGLLTLPGYKTNYNDRNYLPADLPANEGYSAAE MUL_0757|M.ulcerans_Agy99 IVRWPGPILIGAVALALVGLLTLPGYKTNYNDRNYLPADLPANEGYSAAE MAV_2510|M.avium_104 VVRWPGPILVLTIGVALVGLLTLPGYRTNYNDRNYLPTDLPANEGYAAAD MSMEG_4383|M.smegmatis_MC2_155 VVRWPGAVLMATVLLSLVGLLALPGYRTNYNDRNYLPDDLPAQEGFAAAE MLBr_02378|M.leprae_Br4923 VVRWPLPILITTCAIAMVGLLALPGYRTNYKDRAYLPASIPANQGFAAAD MAB_2301|M.abscessus_ATCC_1997 IVRWPGPVLAAAMAIAIIGLAALPGYRTSYDDKKYIPKDIPANAGFQAAD :**** .:: : ::::** :****:*.*.*: *:* .:*:: *: .*: Mflv_3435|M.gilvum_PYR-GCK EHFDQARMNPELLMIESDHDLRNSADFLVIDKIAKALFRVEGIARVQAIT Mvan_3189|M.vanbaalenii_PYR-1 RHFDQARMNPELLMIESDHDLRNSADFLVIDKIAKAIFKVEGIARVQAIT TH_3260|M.thermoresistible__bu RHFDPARLNPELLLIESDHDLRNPADFLVIEKIAKAVFQVEGISRVQGIT Mb0695c|M.bovis_AF2122/97 RHFSQARMNPEVLMVESDHDMRNSADFLVINKIAKAIFAVEGISRVQAIT Rv0676c|M.tuberculosis_H37Rv RHFSQARMNPEVLMVESDHDMRNSADFLVINKIAKAIFAVEGISRVQAIT MMAR_1005|M.marinum_M RHFSQARMNPEVLMVESDHDMRNSSDFLVINKIAKAIFGVEGISRVQAIT MUL_0757|M.ulcerans_Agy99 RHFSQARMNPEVLMVESDHDMRNSSDFLVINKIAKAIFGVEGISRVQAIT MAV_2510|M.avium_104 RHFSQARMNPEVLMIESDHDLRNSADFLVIDKIAKTVFRVPGIGRVQAIT MSMEG_4383|M.smegmatis_MC2_155 RHFSPAKMNPELLLIETDHDIRNSADFLVIDKIAKAVFRVPGIGSVQAIT MLBr_02378|M.leprae_Br4923 RHFPQARMKPEILMIESDHDMRNPADFLILDKLARGIFRVPGISRVQAIT MAB_2301|M.abscessus_ATCC_1997 RHFSQARMNPEMLLIESDHDMRNSADFLVIDKIAKAVFRVPGIARVQAIT .** *:::**:*::*:***:**.:***:::*:*: :* * **. **.** Mflv_3435|M.gilvum_PYR-GCK RPDGKPIKHTSIPFQMSMQGTTQRLNEKYMQDRMADMLVQADEMANTIKT Mvan_3189|M.vanbaalenii_PYR-1 RPDGKPIKHTSIPFQMSMQGTTQRLNEKYMQDRMADMLVQADEMANTIAT TH_3260|M.thermoresistible__bu RPEGTPIEHSSIPFMISQQGTLQILNQQYMQDRMADMLVQADEMQLMIDT Mb0695c|M.bovis_AF2122/97 RPDGKPIEHTSIPFLISMQGTSQKLTEKYNQDLTARMLEQVNDIQSNIDQ Rv0676c|M.tuberculosis_H37Rv RPDGKPIEHTSIPFLISMQGTSQKLTEKYNQDLTARMLEQVNDIQSNIDQ MMAR_1005|M.marinum_M RPDGKPIEHTSIPFLISMQGTSQKLTEKYNQDLTTSMLQQVNDIQTNIDQ MUL_0757|M.ulcerans_Agy99 RPDGKPIEHTSIPFLISMQGTSQKLTEKYNQDLTTSMLQQVNDIQTNIDQ MAV_2510|M.avium_104 RPQGTPIEHTSIPFQISMQGVTQQMNQKYQQDQMADMLHQADMMQTTIDS MSMEG_4383|M.smegmatis_MC2_155 RPQGEPLEFSTIPAQMSMGGTLQTMNRKYMLDRADDMLLQADEMQRTIEL MLBr_02378|M.leprae_Br4923 RPDGTAMDHTSIPFQISMQNAGQVQTMKYQKDRMNDLLRQAENMAETIAS MAB_2301|M.abscessus_ATCC_1997 RPQGTPIEHSSIPFLISMQSVGQRQNMKLMKDRMADMKVQADKMGENVVI **:* .:..::** :* .. * . : * : *.: : : Mflv_3435|M.gilvum_PYR-GCK MEKMSGLTAQMADITHSMVTKMEGMVVDIEDLRDSIANFDDFFRPIRNYF Mvan_3189|M.vanbaalenii_PYR-1 MEKMSNLTAQMADITHSMVSKMENMLTDIEDLRDSIANFDDFFRPIRNYF TH_3260|M.thermoresistible__bu MDKMIALMEEMVETTDNMVRDMDEMAAHVAEMRDSISEFDDFFRPIRNYF Mb0695c|M.bovis_AF2122/97 MERMHSLTQQMADVTHEMVIQMTGMVVDVEELRNHIADFDDFFRPIRSYF Rv0676c|M.tuberculosis_H37Rv MERMHSLTQQMADVTHEMVIQMTGMVVDVEELRNHIADFDDFFRPIRSYF MMAR_1005|M.marinum_M MERMHDLTQQMADVTHQMVIQMKGMVVDVEELRNHIADFDDFFRPIRSYF MUL_0757|M.ulcerans_Agy99 MERMHDLTQQMADVTHQMVIQMKGMVVDVEELRNHIADFDDFFRPIRSYF MAV_2510|M.avium_104 MEKMQSITVQMSNDMHVMVQKMHDMTIDINDLRNKMADFEDFFRPMRSYF MSMEG_4383|M.smegmatis_MC2_155 MGRTIELMEEMAATTHSMVGKTHLMVEDVKELRDNISNFDDFLRPLRNYL MLBr_02378|M.leprae_Br4923 MRRMHQLMALLTENTHHILNDTVEMQKTTSKLRDEIANFDDFWRPIRSYF MAB_2301|M.abscessus_ATCC_1997 MKRTLANMTTMAGITHSLVGDMHTLQGTIHEMRDSISNFDDWFRPIRNYL * : : . :: . : .:*: :::*:*: **:*.*: Mflv_3435|M.gilvum_PYR-GCK YWEPHCYNIPVCWALRSVFDTLDGINIMTDDFKAIIPDMKRLDTLMPQMV Mvan_3189|M.vanbaalenii_PYR-1 YWEPHCYNIPVCWALRSVFDTLDGINVMTDDFREILPDMKRLDSLMPQMV TH_3260|M.thermoresistible__bu YWEPHCYNIPVCWAMRSVFDTLDGINTMTDDIQNMLPHMHRLNDLMPQML Mb0695c|M.bovis_AF2122/97 YWEKHCYDIPVCWSLRSVFDTLDGIDVMTEDINNLLPLMQRLDTLMPQLT Rv0676c|M.tuberculosis_H37Rv YWEKHCYDIPVCWSLRSVFDTLDGIDVMTEDINNLLPLMQRLDTLMPQLT MMAR_1005|M.marinum_M YWEKHCFDIPVCWSLRSVFDTLDGVDLMTEDINNLLPLMERLDTLMPQMT MUL_0757|M.ulcerans_Agy99 YWEKHCFDIPVCWSLRSVFDTLDGVDLMTEDINNLLPLMERLDTLMPQMT MAV_2510|M.avium_104 YWEKHCYDIPVCWSLRSVFDALDGIDTMTDDIQSLLPIMDHLDTLMPQMV MSMEG_4383|M.smegmatis_MC2_155 YWEPHCYDIPMCHSMRSIFDALDGMDTMTEAMEELLPDMDRLDALMPRMV MLBr_02378|M.leprae_Br4923 YWERHCFNIPICWSFRSIFDALDGVDQIDERLNSIVGDIKNMDLLMPQML MAB_2301|M.abscessus_ATCC_1997 YWEKHCFDIPMCWAMRSIFDTLDKIDEMTETMDGMVVNMERMDTLMPKMV *** **::**:* ::**:**:** :: : : : :: :..:: ***:: Mflv_3435|M.gilvum_PYR-GCK ALMPEMIETMKTMRTMMLTMYQSQKGQQDQMAAMSEDADAMGEAFDDSMN Mvan_3189|M.vanbaalenii_PYR-1 ALMPEMIETMKTMRTMMLTMYQSQKGQQDQMAAMSEDADAMGEAFDDSMN TH_3260|M.thermoresistible__bu TLLPTTVATMKTMRSMLLTMQATNAGLQDQMAEMQENANAMGEAFDQARN Mb0695c|M.bovis_AF2122/97 AMMPEMIQTMKSMKAQMLSMHSTQEGLQDQMAAMQEDSAAMGEAFDASRN Rv0676c|M.tuberculosis_H37Rv AMMPEMIQTMKSMKAQMLSMHSTQEGLQDQMAAMQEDSAAMGEAFDASRN MMAR_1005|M.marinum_M AMMPEMIQTMKSMKAQMLSMHSTQQGLQDQMAAMQEDSSAMGEAFDSSRN MUL_0757|M.ulcerans_Agy99 AMMPEMIQTMKSMKAQMLSMHSTQQGLQDQMAAMQEDSSAMGEAFDSSRN MAV_2510|M.avium_104 ALMPSMIENMKAMKTTMLTMYSTQKGLQDQQNEAQKNSNAMGKAFDASKN MSMEG_4383|M.smegmatis_MC2_155 ALMPPQIETMRKMRTMMLTMHQTQKGLQEQMGAMQEGQTAMGEAFNTAKN MLBr_02378|M.leprae_Br4923 EQFPPMIESMESMRTIMLTMHSTMSGIFDQMNELSDNANTMGKAFDTAKN MAB_2301|M.abscessus_ATCC_1997 SDMSAMIPIMEDMQRMMLTQHSTMSGFYNQMDEMSQNSTAMGKAFDAAKN :. : *. *: :*: : * :* ... :**:**: : * Mflv_3435|M.gilvum_PYR-GCK DDSFYLPPEIFENADFQRGLEQFLSPDGHAVRFIISHEGDPLSPEGVAKI Mvan_3189|M.vanbaalenii_PYR-1 DDSFYLPPEIFENKDFQRGLEQFLSPDGHAVRFIISHEGDPLSPEGVAKI TH_3260|M.thermoresistible__bu DDSFYLPPEAFDNPDFQRGLEQFLSPDGHAVRFIISHQGDPMTPEGLAKI Mb0695c|M.bovis_AF2122/97 DDSFYLPPEVFDNPDFQRGLEQFLSPDGHAVRFIISHEGDPMSQAGIARI Rv0676c|M.tuberculosis_H37Rv DDSFYLPPEVFDNPDFQRGLEQFLSPDGHAVRFIISHEGDPMSQAGIARI MMAR_1005|M.marinum_M DDSFYLPPEVFNNPDFKRGLEQFLSPDGHAVRFIISHEGDPMSQAGINHI MUL_0757|M.ulcerans_Agy99 DDSFYLPPEVFNNPDFKRGLEQFLSPDGHAVRFIISHEGDPMSQAGINHI MAV_2510|M.avium_104 DDSFYLPPETFNNKEFKKGMKNFISPDGHAVRFIISHDGDPMTQEGISHI MSMEG_4383|M.smegmatis_MC2_155 DDTFYLPPEIFNNADFKRGMDSFISPDGKAVRFIISHEGDPLTPEGIKLI MLBr_02378|M.leprae_Br4923 DDSFYLPPEVFKNTDFKRAMKSFLSSDGHAARFIILHRGDPASVAGIASI MAB_2301|M.abscessus_ATCC_1997 DDSFYLPPEIFDNADFKRGMKSFLSPDGKAVRMIISHRGDPATPEGLSHV **:****** *.* :*::.:..*:*.**:*.*:** * *** : *: : Mflv_3435|M.gilvum_PYR-GCK DKIKTAAKEAVKGTPLEGSKIYLGGTAAVFKDMQDGNNYDLLIAGIAALG Mvan_3189|M.vanbaalenii_PYR-1 DKIKTAAKEAIKGTPLEGSKIYLGGTAATFKDMQDGNNYDLLIAGISALG TH_3260|M.thermoresistible__bu EPIKKAAVEAIKGTPLEGSRVYLGGTAAVFKDMSDGTKYDLIIAAIAAVC Mb0695c|M.bovis_AF2122/97 AKIKTAAKEAIKGTPLEGSAIYLGGTAAMFKDLSDGNTYDLMIAGISALC Rv0676c|M.tuberculosis_H37Rv AKIKTAAKEAIKGTPLEGSAIYLGGTAAMFKDLSDGNTYDLMIAGISALC MMAR_1005|M.marinum_M DKIKTAAKEAIKGTPLEGSTIYLGGTAAMFKDLSDGNTFDLMIAGISALC MUL_0757|M.ulcerans_Agy99 DKIKTAAKEAIKGTPLEGSTIYLGGTVAMFKDLSDGNTFDLMIAGISALC MAV_2510|M.avium_104 GAIKKAAYEALKGTPLEGSKIYLAGTASIYKDLSDGNNYDLLIAGISSLC MSMEG_4383|M.smegmatis_MC2_155 DQIKLAAKEAMKNTPWEGSKIYVGGTAAAFKDMQEGNNYDLIIAGISALC MLBr_02378|M.leprae_Br4923 NAIRTAAEEALKGTPLEDTKIYLAGTAAVFKDIDEGANWDLVIAGISSLC MAB_2301|M.abscessus_ATCC_1997 EPIKQAAIEAVKGTPLEDAKIELGGTAAVFKDMSDGAKYDLMIAGISALC *: ** **:*.** *.: : :.**.: :**:.:* .:**:**.*::: Mflv_3435|M.gilvum_PYR-GCK LIFIIMLILTRAVVAAAVIVGTVVLSLAASFGLSVLFWQHILGQPLHWMV Mvan_3189|M.vanbaalenii_PYR-1 LIFIIMLILTRAIVAAAVIVGTVVLSLAASFGLSVLFWQHILGTELHWMV TH_3260|M.thermoresistible__bu LIFIIMLILTRAVVAAAVIVGTVTLSLAASFGVSVLIWQYIVGLEMHWMV Mb0695c|M.bovis_AF2122/97 LIFIIMLIITRSVVAAAVIVGTVVLSLGASFGLSVLIWQHILGIELHWLV Rv0676c|M.tuberculosis_H37Rv LIFIIMLITTRSVVAAAVIVGTVVLSLGASFGLSVLIWQHILGIELHWLV MMAR_1005|M.marinum_M LIFIIMLIITRSVVAAAVIVGTVVLSLGASFGLSVLIWQHILGIELHWLV MUL_0757|M.ulcerans_Agy99 LIFIIMLIITRSVVAAAVIVGTVVLSLGASFGLSVLIWQHVLGIELHWLV MAV_2510|M.avium_104 LIFIIMLIITRGVVASAVIVGTVLLSLGASFGLSVLIWQHLIGIELHWMV MSMEG_4383|M.smegmatis_MC2_155 LIFIIMLLITRSVVAAAVIVGTVLVSLGASFGLSILVWQHILGIDLHFMV MLBr_02378|M.leprae_Br4923 LIFIIMLIITRAFVAAAVIVGTVALSLGASFGLSVLLWQHILGIELHYLV MAB_2301|M.abscessus_ATCC_1997 LIFLIMLLITRSFVASLVIVGTVALSLGASFGLSVIIWQYILGIELHWLV ***:***: **..**: ****** :**.****:*::.**:::* :*::* Mflv_3435|M.gilvum_PYR-GCK LAMAVIILLAVGADYNLLLVSRLKEEIHAGIGTGIIRAMGGSGSVVTAAG Mvan_3189|M.vanbaalenii_PYR-1 LAMAVIVLLAVGADYNLLLVSRLKEEIHAGIGTGIIRAMGGSGSVVTAAG TH_3260|M.thermoresistible__bu FPMALIILLAVGADYNLLVVARLREEIPAGLNTGMIRAMGGSGSVVTAAG Mb0695c|M.bovis_AF2122/97 LAMAVIILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGSGSVVTAAG Rv0676c|M.tuberculosis_H37Rv LAMAVIILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGSGSVVTAAG MMAR_1005|M.marinum_M LAMAVIILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGSGSVVTAAG MUL_0757|M.ulcerans_Agy99 LAMAVIILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGSGSVVTAAG MAV_2510|M.avium_104 LAMSVIILLAVGADYNLLLVARFKEEIHAGLNTGIIRSMGGTGSVVTSAG MSMEG_4383|M.smegmatis_MC2_155 MAMAVIVLLAVGADYNLLLVARLKEELPAGINTGIIRAMGGSGSVVTAAG MLBr_02378|M.leprae_Br4923 LAMSVIVLLAVGSDYNLLLVSRFKQEIQAGLKTGIIRSMGGTGKVVTNAG MAB_2301|M.abscessus_ATCC_1997 MQMAIIVLLAVGSDYNLLLVSRLKEELHGGLKTGIIRSMGGTGSVVTSAG : *::*:*****:*****:*:*:::*: .*: **:**:***:*.*** ** Mflv_3435|M.gilvum_PYR-GCK LVFALTMMSMSVSELTVIGQVGTTIGLGLLFDTLVIRAFMTPSIAALLGP Mvan_3189|M.vanbaalenii_PYR-1 LVFALTMMSMAVSELTVIGQVGTTIGLGLLFDTLVIRAFMTPSIAALLGP TH_3260|M.thermoresistible__bu LVFGLTMMVMVVSDLTVMGQVGTTIGLGLLFDTFVVRSFMMPSIATLLGR Mb0695c|M.bovis_AF2122/97 LVFAFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTPSIAALLGK Rv0676c|M.tuberculosis_H37Rv LVFAFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTPSIAALLGK MMAR_1005|M.marinum_M LVFAFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTPSIAALLGK MUL_0757|M.ulcerans_Agy99 LVFAFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTPSIAALLGK MAV_2510|M.avium_104 LVFAFTMMTMAVSELTVIGQVGTTIGLGLLFDTLIVRSLMTPSIAALLGK MSMEG_4383|M.smegmatis_MC2_155 LVFAFTMMSMLVSEMTVVAQVGTTIGMGLLFDTLVIRSFMTPSIAALLGR MLBr_02378|M.leprae_Br4923 LVFAFTMASMVVSDLRVIGQVGTTIGLGLLFDTLIVRSFMMPSIAALLGR MAB_2301|M.abscessus_ATCC_1997 LVFAFTMAVMVVSDLRIIGQVGTTIALGLLFDTLIVRSFMTPAVATLLGR ***.:** : **:: ::.******.:******:::*::* *::*:*** Mflv_3435|M.gilvum_PYR-GCK WFWWPQRVRTRPVPAPWPRSGGLQSDPSEGVRA---------------- Mvan_3189|M.vanbaalenii_PYR-1 WFWWPQRVRTRPVPAPWPRPGGLQSDPSEGVKV---------------- TH_3260|M.thermoresistible__bu WFWWPQFVRKRPVPQPWPSVPPRGPATTDRVSV---------------- Mb0695c|M.bovis_AF2122/97 WFWWPQVVRQRPVPQPWPSPASARTFALV-------------------- Rv0676c|M.tuberculosis_H37Rv WFWWPQVVRQRPIPQPWPSPASARTFALV-------------------- MMAR_1005|M.marinum_M WFWWPQVVRQRPAPQPWPTPAPTP--ATTSV------------------ MUL_0757|M.ulcerans_Agy99 WFWWPQVVRQRPAPQPWPTPAPTPPPATTSV------------------ MAV_2510|M.avium_104 WFWWPQRVRQRPVPSPWPKPAAQEREVLADA------------------ MSMEG_4383|M.smegmatis_MC2_155 WFWWPQVVRARPARGVVARALERDKAATH-------------------- MLBr_02378|M.leprae_Br4923 WFWWPQQGRTRPLLTVAAPVGLPPDRSLVYSD----------------- MAB_2301|M.abscessus_ATCC_1997 WFWWPLNVRTRPLPPPRTTVAADPTPPPVPVGPGHGDDPITTEFPRPSV ***** * ** .