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VSTTQSVPGQTGTTAAERPFVARMIRTLAVPIILFWLAVVVLLSVFVPSLEVVGQERSVSLSPTDAPSVV ALNRIGHVFNEGETDSVAMIILEGDKPLGDDAHKFYDGLIRKLRADKKHVLSIQDFWGDPLTAAGAQSND GMAATVQVSLAGKQGELLANESVEAVRKIVDATPAPPGVKAYVTGGPAMAADLHKSGDRSMAKITLTTVA VILIMLLFVYRSPVTVFLLLVTVGLELTAARGAVALLGHSGLIGLSTFAVSLLTSLAIAAGTDYGIFIVG RYQEARQAGEDRESAFYTMYRGTAHVILGSGLTISAATFCLSFTRMPYFQTLGIPCSVGMLVALLVALTL APAVLVVGGRFGAFDPKRVLQVRGWRRVGTAIVRWPLPILAVTCAVALVGLITLPGYRPSYNDRAYLPSF IPANQGLAVADRHFSQARINPEILMIESDHDMRNPTDFLVLDKLAKGIFRVPGISRVQAITRPSGTTMDH TTIPFRLSMQNAGQVQSLHYQRARMNDLLTQADEMAKTIALTRRMYELSSQLADNTHRMVGDTIEMQQIT NELRDKLADFDDFWRPIRSYLYWEKHCYDIPNCWTFRSLFDALDGLDQIDEKLGVMVGDLENVDRLMPQM TETFPPMIESMEHIRTMMLTMHSTMSGMVDQMTELSENANAMGKAFDTAKNDDSFYLPPEVFENADFKRA MGSFLSPDGHAARFIILHRSDPASASGIASIDKIRTAAEESLKGTPLENATIYLAGVGAIFKDVSEGAKW DLLIAGIASLCLIFVIMLILTRALVAAGVIVGTVAISLGASFGLSVLLWQHIIGMPLHWLVIAMSVIVLL AVGSDYNLLLVSRFKQEIPAGINTGIIRSMGGTGKVVTNAGLVFAFTMASMVVSDVRMIGQVGTTIGLGL LFDTLVVRAFMTPAIAALLGRWFWWPLRVRSRPDRRAIQRAAQSDTEPAPVESAPATAGS
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_0255 | mmpL5_4 | - | 100% (970) | transmembrane transport protein, MmpL5_4 |
M. marinum M | MMAR_0771 | mmpL5_2 | 0.0 | 79.05% (945) | transmembrane transport protein MmpL5_2 |
M. marinum M | MMAR_4429 | - | 0.0 | 72.02% (922) | transmembrane transport protein, MmpL |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0458c | mmpL4 | 0.0 | 77.52% (943) | transmembrane transport protein MmpL4 |
M. gilvum PYR-GCK | Mflv_3435 | - | 0.0 | 61.51% (943) | transport protein |
M. tuberculosis H37Rv | Rv0450c | mmpL4 | 0.0 | 77.52% (943) | transmembrane transport protein MmpL4 |
M. leprae Br4923 | MLBr_02378 | - | 0.0 | 76.67% (930) | hypothetical protein MLBr_02378 |
M. abscessus ATCC 19977 | MAB_4116c | - | 0.0 | 63.81% (934) | putative membrane protein, MmpL |
M. avium 104 | MAV_3249 | - | 0.0 | 64.14% (912) | Mmp14A protein |
M. smegmatis MC2 155 | MSMEG_3496 | - | 0.0 | 61.76% (952) | MmpL4 protein |
M. thermoresistible (build 8) | TH_3056 | - | 0.0 | 60.73% (927) | PUTATIVE Mmp14a protein |
M. ulcerans Agy99 | MUL_0757 | mmpL5 | 0.0 | 61.62% (951) | transmembrane transport protein, MmpL5 |
M. vanbaalenii PYR-1 | Mvan_3189 | - | 0.0 | 62.68% (927) | transport protein |
CLUSTAL 2.0.9 multiple sequence alignment Mb0458c|M.bovis_AF2122/97 ------MSTKFANDSNTNARPEKPFIARMIHAFAVPIILGWLAVCVVVTV Rv0450c|M.tuberculosis_H37Rv ------MSTKFANDSNTNARPEKPFIARMIHAFAVPIILGWLAVCVVVTV MLBr_02378|M.leprae_Br4923 ------MTVKCANDLDTHTKP--PFVARMIHRFAVPIILVWLAIAVTVSV MMAR_0255|M.marinum_M -----MSTTQSVPGQTGTTAAERPFVARMIRTLAVPIILFWLAVVVLLSV MAB_4116c|M.abscessus_ATCC_199 ----------MSADDGK-VKSHRPIMATIIRRGAVFIILGWLAITVLLTV TH_3056|M.thermoresistible__bu ----------MSVLDRVGVEPRRPRVASFIRRYSVLIILGWVALTVLATV MAV_3249|M.avium_104 ----------------------------------MFIILGWVALTLLVTF Mflv_3435|M.gilvum_PYR-GCK MSAPVSDARTDEF--PAAHGPHRSFIPRMIRLFAVPIILGWIALIVVVNV Mvan_3189|M.vanbaalenii_PYR-1 MSAPVSDARTDEF--PAARQPHRPFIPRMIRLFAVPIILGWIALIVILNV MUL_0757|M.ulcerans_Agy99 MTATTTDTPTDVV--PPAEHPPRPFIPRMIRTFAVPLILGWVLLIAVLNS MSMEG_3496|M.smegmatis_MC2_155 MSNPSHDAPTDAMGVSGPKHARPGGIAKWIRVLAVPIILVWVAIIAVLNT : :** *: : . Mb0458c|M.bovis_AF2122/97 FVPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKEGDSDSFAMVIIEGN Rv0450c|M.tuberculosis_H37Rv FVPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKEGDSDSFAMVIIEGN MLBr_02378|M.leprae_Br4923 FIPSLEDVGQERSVSLSPKDAPSYIAMQKMGQVFNEGNSDSVIMIVLEGD MMAR_0255|M.marinum_M FVPSLEVVGQERSVSLSPTDAPSVVALNRIGHVFNEGETDSVAMIILEGD MAB_4116c|M.abscessus_ATCC_199 KVPPLEIVEREHSVSLSPPDAPSVKAMTQMGKVFQESNSESVAVIVLEGE TH_3056|M.thermoresistible__bu AVPPLEAVEREKSLSLIPYDAPAFAAMHRMGELFDEPDSESIAIIVLEGQ MAV_3249|M.avium_104 GVPRLEIVGQQHSVPLAPQDAPAVQAMQRMGRDFKESDSDSFAMLVLEGQ Mflv_3435|M.gilvum_PYR-GCK TVPQLETVGEAQAVSMSPNDAPSMISMKKVGELFEEGDSDSSVMIVFEGD Mvan_3189|M.vanbaalenii_PYR-1 TVPQLEAVGEARAVSMSPNEAPSLISMKKVGELFREGDSDSSVMIVFEGD MUL_0757|M.ulcerans_Agy99 VVPQLEVVGQMQAVSMSPDAAPSMISMKHIGKVFREGDSDSAAMIVLEGQ MSMEG_3496|M.smegmatis_MC2_155 VVPQLDVVGEMRSVSMSPDDAPSVIAMKRVGEVFEEFKSNSSVMIVLEGE :* *: * . :::.: * **: :: ::* * * .::* ::::**: Mb0458c|M.bovis_AF2122/97 QPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDPLTAAGVQSNDGKAAY Rv0450c|M.tuberculosis_H37Rv QPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDPLTAAGVQSNDGKAAY MLBr_02378|M.leprae_Br4923 KPLGDDAHRFYDGLIRKLRADK-HVQSVQDFWGDPLTAPGAQSNDGKAAY MMAR_0255|M.marinum_M KPLGDDAHKFYDGLIRKLRADKKHVLSIQDFWGDPLTAAGAQSNDGMAAT MAB_4116c|M.abscessus_ATCC_199 GTLGDDAHKYYDAVIRQLKDDPKHVQHVQDFWGDPLTAGAAQSADGKAAY TH_3056|M.thermoresistible__bu EPLGLEAHEYYDQLISQLREHPQYVQHIRDFWGDPLTAGAAQSDDGKAAF MAV_3249|M.avium_104 QQLGDDAHAYYDKLVRELRNDTKHVEHVQDLWGDRLTQAGAQSPDGKAVY Mflv_3435|M.gilvum_PYR-GCK QPLGDEAHAWYDELVDRLEADTAHVQSVQDFWSDPLTASGSQSNDGKAAY Mvan_3189|M.vanbaalenii_PYR-1 QPLGDEAHAWYDELVERLRADTKHVQSVQDFWSDPLTASGSQSNDGKAAY MUL_0757|M.ulcerans_Agy99 EPLGAAAHKFYDKMITKLRADTKHVQSVQDFWGDPLTATGAQSGDGKAAY MSMEG_3496|M.smegmatis_MC2_155 QPLGDEAHKYYDEIVDKLEADPAHVEHVQDFWGDPLTASGAQSPDGLASY ** ** :** :: .*. . :* ::*:*.* ** . ** ** * Mb0458c|M.bovis_AF2122/97 VQLSLAGNQGTPLANESVEAVRSIVESTP-APPGIKAYVTGPSALAADMH Rv0450c|M.tuberculosis_H37Rv VQLSLAGNQGTPLANESVEAVRSIVESTP-APPGIKAYVTGPSALAADMH MLBr_02378|M.leprae_Br4923 VQLSLAGNQGELLAQESIDAVRKIVVQTP-APPGITAWVTGASALIADMH MMAR_0255|M.marinum_M VQVSLAGKQGELLANESVEAVRKIVDATP-APPGVKAYVTGGPAMAADLH MAB_4116c|M.abscessus_ATCC_199 VQLNLTGRFGQADANESVEAVQKVVRETPGLPPGVKAYVTGPAAIVSDMA TH_3056|M.thermoresistible__bu VQVNLVGRFGQAKVNEAVRAVQEIVERTP-APEGVETFVTGPAALGADAG MAV_3249|M.avium_104 VQLNLAGNQGTTLGQESVAAVRDVIARIP-PPAGLKAYVTGPAALFSDMQ Mflv_3435|M.gilvum_PYR-GCK VQVKLSGNQGEALANESVKAVQQTVSSLE-PPPGVRAFVTGPAALAADQH Mvan_3189|M.vanbaalenii_PYR-1 VQVKLAGNQGESLANESVQAAQEIVRSLE-PPPGVRAFVTGPAALAADQH MUL_0757|M.ulcerans_Agy99 VQVKLAGNQGESLANESVEAVKTIVDSLQ-APPGVKVYVTGSAALVADQQ MSMEG_3496|M.smegmatis_MC2_155 VQVYTRGNQGEALANESVEAVQDIVESVP-APPGVKAYVTGPAALSADQH **: *. * :*:: *.: : * *: .:*** .*: :* Mb0458c|M.bovis_AF2122/97 HSGDRSMARITMVTVAVIFIMLLLVYRSIITVVLLLITVGVELTAARGVV Rv0450c|M.tuberculosis_H37Rv HSGDRSMARITMVTVAVIFIMLLLVYRSIITVVLLLITVGVELTAARGVV MLBr_02378|M.leprae_Br4923 HSGDKSMIRITATSVIVILVTLLLVYRSFITVILLLFTVGIESAVARGVV MMAR_0255|M.marinum_M KSGDRSMAKITLTTVAVILIMLLFVYRSPVTVFLLLVTVGLELTAARGAV MAB_4116c|M.abscessus_ATCC_199 ESGNRTVILITLVSVGVIFLMLLLLYRSIITVIILLFTVGIELQVARGLV TH_3056|M.thermoresistible__bu DSGTATVILITLVTVAVIFLMLLFFFRSFLTVIVLLLTVAVELQVARGLV MAV_3249|M.avium_104 LAGDRSILKMTLIGALIIFIVLLFVYRSVTTVVLLLLTVGIEVFAARGVI Mflv_3435|M.gilvum_PYR-GCK IAGDRSMRLIEAATFTVIIVMLLLVYRSIVTVLITLVMVVMSLATARGVV Mvan_3189|M.vanbaalenii_PYR-1 IASDRSVRVIELVTFAVIIVMLLLVYRSIVTVLLTLVMVVLSLATARGVV MUL_0757|M.ulcerans_Agy99 LAGDRSLQLIEMVTFTVIIVMLLLVYRSIITAAIMLTMVVLGLLATRGGV MSMEG_3496|M.smegmatis_MC2_155 VASDRSVRVIEALTFAVIITMLLLVYRSIVTVILTLVMVVLSLSAARGMI :. :: : :*: **:.:** *. : * * : .:** : Mb0458c|M.bovis_AF2122/97 AVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFIIGRYQEARQAGEDKEA Rv0450c|M.tuberculosis_H37Rv AVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFIIGRYQEARQAGEDKEA MLBr_02378|M.leprae_Br4923 ALLGHTGLIGLSTFAVNLLTSLAIAAGTDYGIFITGRYQEARQANENKEA MMAR_0255|M.marinum_M ALLGHSGLIGLSTFAVSLLTSLAIAAGTDYGIFIVGRYQEARQAGEDRES MAB_4116c|M.abscessus_ATCC_199 AFLGMHGIVGLTTFVVNLLVSVGIAAGTDYGIFFAGRYQEARQSGEDRES TH_3056|M.thermoresistible__bu AYLGLQGWVGLTTYVVNLLVSVGIAAGTDYGIFFFGRYQEAREAGEDRDS MAV_3249|M.avium_104 AFVANNNLMPLSTFAVNLLVALAMAAGTDYAIFFFGRYQEAREAGEDRAT Mflv_3435|M.gilvum_PYR-GCK AFLGHHEIIGLSTFATNLLVTLAIAAATDYAIFLIGRYQEARTAGEDKET Mvan_3189|M.vanbaalenii_PYR-1 AFLGWHEIIGLSLFATNLLVTLAIAAATDYAIFLIGRYQEARTNGEDKES MUL_0757|M.ulcerans_Agy99 AFLGYHRIIGLSTFATNLLVVLAIAAATDYAIFLIGRYQEARGLGQDRES MSMEG_3496|M.smegmatis_MC2_155 AFLGYHEIIGLSVFATNLLTTLAIAAATDYAIFLIGRYQEARSVGEDREQ * :. : *: :...**. :.:**.***.**: ******* .::: Mb0458c|M.bovis_AF2122/97 AYYTMYRGTAHVILGSGLTITGATFCLSFARMPYFQTLGIPCAVGMLVAV Rv0450c|M.tuberculosis_H37Rv AYYTMYRGTAHVILGSGLTIAGATFCLSFARMPYFQTLGIPCAVGMLVAV MLBr_02378|M.leprae_Br4923 AFYTMYRGTFHVILGSGLTISGATFCLSFARMPYFQTLGVPCAVGMLIAV MMAR_0255|M.marinum_M AFYTMYRGTAHVILGSGLTISAATFCLSFTRMPYFQTLGIPCSVGMLVAL MAB_4116c|M.abscessus_ATCC_199 AYYTAYKGVAKVVLASGLTIAGAIACLHFTRLPYFKPLGIPGAVGILVAV TH_3056|M.thermoresistible__bu AYFTTYRSVAKVVLASGLTIAGAIACLSFTRLPHFQPLGIPGAVGLLVAV MAV_3249|M.avium_104 AYFTTYRSVAPVVLGSGLTIAGAMLCLSFTRMPIFQTMGLPCSVGMLISV Mflv_3435|M.gilvum_PYR-GCK AYYTMFHGTAHVVLGSGLTIAGATFCLSFTRLPYFQTMGVPLAIGMFVVV Mvan_3189|M.vanbaalenii_PYR-1 AYYTMFHGTAHVVLGSGLTIAGATYCLSFTRLPYFQTLGVPLAIGMFVVV MUL_0757|M.ulcerans_Agy99 AYYTMFGGTAHVVLGSGLTIAGATFCLSFTRLPYFQTLGVPLAIGMVIVV MSMEG_3496|M.smegmatis_MC2_155 SYYTMFHSTAHVVLGSGMTIAGATLCLHFTRMPYFQSLGIPLAIGMSVVV :::* : .. *:*.**:**:.* ** *:*:* *:.:*:* ::*: : : Mb0458c|M.bovis_AF2122/97 AVALTLGPAVLHVGSRFG-LFDPKRLLKVRGWRRVGTVVVRWPLPVLVAT Rv0450c|M.tuberculosis_H37Rv AVALTLGPAVLHVGSRFG-LFDPKRLLKVRGWRRVGTVVVRWPLPVLVAT MLBr_02378|M.leprae_Br4923 AVALTLGPAVLTVGSRFG-LFEPKRLIKVRGWRRIGTVVVRWPLPILITT MMAR_0255|M.marinum_M LVALTLAPAVLVVGGRFG-AFDPKRVLQVRGWRRVGTAIVRWPLPILAVT MAB_4116c|M.abscessus_ATCC_199 AVALTLVPACIAAGSRFG-LFDPKRQVTTRRWRRVGTAIVRWPGPILAAT TH_3056|M.thermoresistible__bu AVALTLVPATIALGSRFG-LFEPKRRVMTHRWRRIGTAVVRWPVPILTAA MAV_3249|M.avium_104 FIALTLVPAVLTVGGGFG-LFDPKRAIGFGRWRRIGTAIVRWPAPILTAT Mflv_3435|M.gilvum_PYR-GCK MAGVVLMVACISVATRFGKLLEPKRAMRIRGWRKIGAAIVRWPGPILVAT Mvan_3189|M.vanbaalenii_PYR-1 MAGVILMVAMISVATRFGKLLEPKRAMRIRGWRKIGAAVVRWPGPILVAT MUL_0757|M.ulcerans_Agy99 ATALTLGPALIAVMSRFGKLLEPKRMARVRGWRKIGAAIVRWPGPILIGA MSMEG_3496|M.smegmatis_MC2_155 LASLTMGAAIISVASRFGKTFEPKRAMRTRGWRKLGAAVVRWPAPILVTT .: : * : ** ::*** **::*:.:**** *:* : Mb0458c|M.bovis_AF2122/97 CAIALVGLLALPGYKTSYNDRDYLPDFIPANQGYAAADRHFSQARM-KPE Rv0450c|M.tuberculosis_H37Rv CAIALVGLLALPGYKTSYNDRDYLPDFIPANQGYAAADRHFSQARM-KPE MLBr_02378|M.leprae_Br4923 CAIAMVGLLALPGYRTNYKDRAYLPASIPANQGFAAADRHFPQARM-KPE MMAR_0255|M.marinum_M CAVALVGLITLPGYRPSYNDRAYLPSFIPANQGLAVADRHFSQARI-NPE MAB_4116c|M.abscessus_ATCC_199 VAVALIGLLTLPGYNPSYTDAKFIPQDIPATQGLVAASRHFPESKMSTPD TH_3056|M.thermoresistible__bu VALSLVGLLTLPGYNPSYSDQEFIPDDIPASEGYKAAARHFPASAMSVPD MAV_3249|M.avium_104 IAVALVGLVTLPGYKTSYNNRLYMPDSVPANVGYAAADRHFTQSRM-MPE Mflv_3435|M.gilvum_PYR-GCK MAITLVGLLALPGYKTNYNDRDYLPADLPANQGYAVADEHFDQARM-NPE Mvan_3189|M.vanbaalenii_PYR-1 LAITLVGLLALPGYKTNYNDRTYLPADLPANEGYAVADRHFDQARM-NPE MUL_0757|M.ulcerans_Agy99 VALALVGLLTLPGYKTNYNDRNYLPADLPANEGYSAAERHFSQARM-NPE MSMEG_3496|M.smegmatis_MC2_155 IALSVVGLLALPGYQTNYNDRRYLPQDLPANTGYAAADRHFSQARM-NPE *::::**::****...*.: ::* :**. * .* .** : : *: Mb0458c|M.bovis_AF2122/97 ILMIESDHDMRNPADFLVLDKLAKGIFRVPGISRVQAITRPEGTTMDHTS Rv0450c|M.tuberculosis_H37Rv ILMIESDHDMRNPADFLVLDKLAKGIFRVPGISRVQAITRPEGTTMDHTS MLBr_02378|M.leprae_Br4923 ILMIESDHDMRNPADFLILDKLARGIFRVPGISRVQAITRPDGTAMDHTS MMAR_0255|M.marinum_M ILMIESDHDMRNPTDFLVLDKLAKGIFRVPGISRVQAITRPSGTTMDHTT MAB_4116c|M.abscessus_ATCC_199 ILLIEANHDMRNSADLLVLNRLAKAVFAVPGIANVQSITRPEGTQIEHSS TH_3056|M.thermoresistible__bu VVLIEADRDMRNPADLLVLNKVAKKIFEVPGVANVQSVTRPEGRQIEHTT MAV_3249|M.avium_104 LLMIESDHDMRNPADFLVLHRLAKGVFGVHGISRVQGITRPEGTPIQHTS Mflv_3435|M.gilvum_PYR-GCK LLMIESDHDLRNSADFLVIDKIAKALFRVEGIARVQAITRPDGKPIKHTS Mvan_3189|M.vanbaalenii_PYR-1 LLMIESDHDLRNSADFLVIDKIAKAIFKVEGIARVQAITRPDGKPIKHTS MUL_0757|M.ulcerans_Agy99 VLMVESDHDMRNSSDFLVINKIAKAIFGVEGISRVQAITRPDGKPIEHTS MSMEG_3496|M.smegmatis_MC2_155 LLMIESDHDLRNSADFLVVDRIAKRVFQVPGISRVQAITRPQGTPIEHTS ::::*:::*:**.:*:*::.::*: :* * *::.**.:***.* :.*:: Mb0458c|M.bovis_AF2122/97 IPFQISMQNAGQLQTIKYQRDRANDMLKQADEMATTIAVLTRMHSLMAEM Rv0450c|M.tuberculosis_H37Rv IPFQISMQNAGQLQTIKYQRDRANDMLKQADEMATTIAVLTRMHSLMAEM MLBr_02378|M.leprae_Br4923 IPFQISMQNAGQVQTMKYQKDRMNDLLRQAENMAETIASMRRMHQLMALL MMAR_0255|M.marinum_M IPFRLSMQNAGQVQSLHYQRARMNDLLTQADEMAKTIALTRRMYELSSQL MAB_4116c|M.abscessus_ATCC_199 VPFMLSMSNASQRLSLPFQRARMDDMLKQADDMSKTIALMQRMSDLMNQM TH_3056|M.thermoresistible__bu IPFMLSMSQASQRLALPFQRARMDDMLKQADELTETIALMRRMQSLMEKM MAV_3249|M.avium_104 IPFLLSMQQATMHQDIQYMKARMDDMLVQADLMRKQIEIMRHIYELQKRL Mflv_3435|M.gilvum_PYR-GCK IPFQMSMQGTTQRLNEKYMQDRMADMLVQADEMANTIKTMEKMSGLTAQM Mvan_3189|M.vanbaalenii_PYR-1 IPFQMSMQGTTQRLNEKYMQDRMADMLVQADEMANTIATMEKMSNLTAQM MUL_0757|M.ulcerans_Agy99 IPFLISMQGTSQKLTEKYNQDLTTSMLQQVNDIQTNIDQMERMHDLTQQM MSMEG_3496|M.smegmatis_MC2_155 IPFQISMSGTTQMMNMKYMQDRMADMLVMADEMQKSVDTMEEMLKITREM :** :**. : : : .:* .: : : .: : : Mb0458c|M.bovis_AF2122/97 ASTTHRMVGDTEEMKEITEELRDHVADFDDFWRPIRSYFYWEKHCYGIPI Rv0450c|M.tuberculosis_H37Rv ASTTHRMVGDTEEMKEITEELRDHVADFDDFWRPIRSYFYWEKHCYGIPI MLBr_02378|M.leprae_Br4923 TENTHHILNDTVEMQKTTSKLRDEIANFDDFWRPIRSYFYWERHCFNIPI MMAR_0255|M.marinum_M ADNTHRMVGDTIEMQQITNELRDKLADFDDFWRPIRSYLYWEKHCYDIPN MAB_4116c|M.abscessus_ATCC_199 VDTTHRMVSTTKDLQQDMRTLRDHIEDFEDFWRPIRNYFYWDKHCFDIPI TH_3056|M.thermoresistible__bu VATTHSMVGTTHELLDTTRDLRDHIADFDDFFRPIRNYFHWEPHCYNIPI MAV_3249|M.avium_104 TDITHDSIVKTKEMAAVLWELRDKMSDFEDFWRPLRSYFYWEKHCYDIPI Mflv_3435|M.gilvum_PYR-GCK ADITHSMVTKMEGMVVDIEDLRDSIANFDDFFRPIRNYFYWEPHCYNIPV Mvan_3189|M.vanbaalenii_PYR-1 ADITHSMVSKMENMLTDIEDLRDSIANFDDFFRPIRNYFYWEPHCYNIPV MUL_0757|M.ulcerans_Agy99 ADVTHQMVIQMKGMVVDVEELRNHIADFDDFFRPIRSYFYWEKHCFDIPV MSMEG_3496|M.smegmatis_MC2_155 SDTTHSMVGKMHGMVEDIKELRDHIADFDDFLRPIRNYFYWEPHCDSIPV ** : : **: : :*:** **:*.*::*: ** .** Mb0458c|M.bovis_AF2122/97 CWSFRSIFDALDGIDKLSEQIGVLLGDLREMDRLMPQMVAQIPPQIEAME Rv0450c|M.tuberculosis_H37Rv CWSFRSIFDALDGIDKLSEQIGVLLGDLREMDRLMPQMVAQIPPQIEAME MLBr_02378|M.leprae_Br4923 CWSFRSIFDALDGVDQIDERLNSIVGDIKNMDLLMPQMLEQFPPMIESME MMAR_0255|M.marinum_M CWTFRSLFDALDGLDQIDEKLGVMVGDLENVDRLMPQMTETFPPMIESME MAB_4116c|M.abscessus_ATCC_199 CWSIRSIFDALDGVDQVTDKMQTLVGDLDELDKLMPQLLEQFPIMIETMK TH_3056|M.thermoresistible__bu CWSIRSIFDALDGINEMTEKMEELVEDMDRLDALMPQMLVQFPQMIETME MAV_3249|M.avium_104 CWSLRNIFETLDGVDTLSDKMTYLLQDLDHMDRLMPQLLEQYPPMIAMSE Mflv_3435|M.gilvum_PYR-GCK CWALRSVFDTLDGINIMTDDFKAIIPDMKRLDTLMPQMVALMPEMIETMK Mvan_3189|M.vanbaalenii_PYR-1 CWALRSVFDTLDGINVMTDDFREILPDMKRLDSLMPQMVALMPEMIETMK MUL_0757|M.ulcerans_Agy99 CWSLRSVFDTLDGVDLMTEDINNLLPLMERLDTLMPQMTAMMPEMIQTMK MSMEG_3496|M.smegmatis_MC2_155 CQSIRSIFDTLDGIDVMTDDIQRLMPDMDRLDELMPQMLTIMPPMIESMK * ::*.:*::***:: : : : :: : .:* ****: * * : Mb0458c|M.bovis_AF2122/97 NMRTMILTMHSTMTGIFDQMLEMSDNATAMGKAFDAAKNDDSFYLPPEVF Rv0450c|M.tuberculosis_H37Rv NMRTMILTMHSTMTGIFDQMLEMSDNATAMGKAFDAAKNDDSFYLPPEVF MLBr_02378|M.leprae_Br4923 SMRTIMLTMHSTMSGIFDQMNELSDNANTMGKAFDTAKNDDSFYLPPEVF MMAR_0255|M.marinum_M HIRTMMLTMHSTMSGMVDQMTELSENANAMGKAFDTAKNDDSFYLPPEVF MAB_4116c|M.abscessus_ATCC_199 STRESMLTMHSTMSGIFAQMDESTENSTAMGKAFDASKNDDSFYLPPDVL TH_3056|M.thermoresistible__bu SSRTMILTMHATMSGIFDQMESSSENATAMGKAFDASHNDDSFYLPPEAL MAV_3249|M.avium_104 DMLRMMLTNHSTMSGIIGQMDSNNKDATAMGEAFDASKNDDSFYLPPDIF Mflv_3435|M.gilvum_PYR-GCK TMRTMMLTMYQSQKGQQDQMAAMSEDADAMGEAFDDSMNDDSFYLPPEIF Mvan_3189|M.vanbaalenii_PYR-1 TMRTMMLTMYQSQKGQQDQMAAMSEDADAMGEAFDDSMNDDSFYLPPEIF MUL_0757|M.ulcerans_Agy99 SMKAQMLSMHSTQQGLQDQMAAMQEDSSAMGEAFDSSRNDDSFYLPPEVF MSMEG_3496|M.smegmatis_MC2_155 TMKTMMLTTQATMGGLQDQMEAAMENQTAMGQAFDASKNDDSFYLPPETF :*: : * ** .: :**:*** : *********: : Mb0458c|M.bovis_AF2122/97 KNKDFQRAMKSFLSSDGHAARFIILHRGDPQSPEGIKSIDAIRTAAEESL Rv0450c|M.tuberculosis_H37Rv KNKDFQRAMKSFLSSDGHAARFIILHRGDPQSPEGIKSIDAIRTAAEESL MLBr_02378|M.leprae_Br4923 KNTDFKRAMKSFLSSDGHAARFIILHRGDPASVAGIASINAIRTAAEEAL MMAR_0255|M.marinum_M ENADFKRAMGSFLSPDGHAARFIILHRSDPASASGIASIDKIRTAAEESL MAB_4116c|M.abscessus_ATCC_199 KNKDFQRVMKIFMSPDGKSSRMLISQRGDPATPEGISRVEPIKTAAEEAL TH_3056|M.thermoresistible__bu ENKDFQRVMEIFLSPDGKAARMLVTQRGDPATPEGMALVEPIYIAAEEAL MAV_3249|M.avium_104 DNADFKKAMSQFLSPDGKAARFIISHRGDPATSEALNRIDKIRSAAEEAL Mflv_3435|M.gilvum_PYR-GCK ENADFQRGLEQFLSPDGHAVRFIISHEGDPLSPEGVAKIDKIKTAAKEAV Mvan_3189|M.vanbaalenii_PYR-1 ENKDFQRGLEQFLSPDGHAVRFIISHEGDPLSPEGVAKIDKIKTAAKEAI MUL_0757|M.ulcerans_Agy99 NNPDFKRGLEQFLSPDGHAVRFIISHEGDPMSQAGINHIDKIKTAAKEAI MSMEG_3496|M.smegmatis_MC2_155 ENPDFKRGMKMFLSPDGHAVRFIISHEGDPMSPEGIKHIDAIKQAAKEAI .* **:: : *:*.**:: *::: :..** : .: :: * **:*:: Mb0458c|M.bovis_AF2122/97 KGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAISSLCLIFIIMLIITR Rv0450c|M.tuberculosis_H37Rv KGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAISSLCLIFIIMLIITR MLBr_02378|M.leprae_Br4923 KGTPLEDTKIYLAGTAAVFKDIDEGANWDLVIAGISSLCLIFIIMLIITR MMAR_0255|M.marinum_M KGTPLENATIYLAGVGAIFKDVSEGAKWDLLIAGIASLCLIFVIMLILTR MAB_4116c|M.abscessus_ATCC_199 KGTPLEHAKLSLAGTAAGVSELVEGSKYDLLIAGVAALCLIFIIMLLMTR TH_3056|M.thermoresistible__bu KGTPLESSRIYLAGSAAGVKDLVEGAKYDLMIAAISAVCLIFMIMVFMTR MAV_3249|M.avium_104 KNTPLENAKIYLAGTASTFKDFRDGSTYDLFIAGVGALCLIFIIMLILTR Mflv_3435|M.gilvum_PYR-GCK KGTPLEGSKIYLGGTAAVFKDMQDGNNYDLLIAGIAALGLIFIIMLILTR Mvan_3189|M.vanbaalenii_PYR-1 KGTPLEGSKIYLGGTAATFKDMQDGNNYDLLIAGISALGLIFIIMLILTR MUL_0757|M.ulcerans_Agy99 KGTPLEGSTIYLGGTVAMFKDLSDGNTFDLMIAGISALCLIFIIMLIITR MSMEG_3496|M.smegmatis_MC2_155 KGTPLEGSKIYLGGTAATFKDLQEGANYDLIIAGIAALCLIFIIMLIITR *.**** : : *.* : . :. :* :**.**.:.:: ***:**:::** Mb0458c|M.bovis_AF2122/97 AFIAAAVIVGTVALSLGASFGLSVLLWQHILAIHLHWLVLAMSVIVLLAV Rv0450c|M.tuberculosis_H37Rv AFIAAAVIVGTVALSLGASFGLSVLLWQHILAIHLHWLVLAMSVIVLLAV MLBr_02378|M.leprae_Br4923 AFVAAAVIVGTVALSLGASFGLSVLLWQHILGIELHYLVLAMSVIVLLAV MMAR_0255|M.marinum_M ALVAAGVIVGTVAISLGASFGLSVLLWQHIIGMPLHWLVIAMSVIVLLAV MAB_4116c|M.abscessus_ATCC_199 SLVAALVIVGTVALSLGASFGLSVLVWQHICGIQINWVVLAMSVIVLLAV TH_3056|M.thermoresistible__bu SVIAALVIVGTVVLSLGASFGMSVLLWQHLLGIQLHWVVLAMSVIVLLAV MAV_3249|M.avium_104 SFIAALVIVGTVTLSLGASFGLSVLIWQYIFGIQLYWMVLPMSVIVLLAV Mflv_3435|M.gilvum_PYR-GCK AVVAAAVIVGTVVLSLAASFGLSVLFWQHILGQPLHWMVLAMAVIILLAV Mvan_3189|M.vanbaalenii_PYR-1 AIVAAAVIVGTVVLSLAASFGLSVLFWQHILGTELHWMVLAMAVIVLLAV MUL_0757|M.ulcerans_Agy99 SVVAAAVIVGTVVLSLGASFGLSVLIWQHVLGIELHWLVLAMAVIILLAV MSMEG_3496|M.smegmatis_MC2_155 AVVASAVIVGTVVISLGASFGLSVLIWQHIIGLELHWMVLAMAVIVLLAV :.:*: ******.:**.****:***.**:: . : ::*:.*:**:**** Mb0458c|M.bovis_AF2122/97 GSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVVTNAGLVFAVTMASMA Rv0450c|M.tuberculosis_H37Rv GSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVVTNAGLVFAVTMASMA MLBr_02378|M.leprae_Br4923 GSDYNLLLVSRFKQEIQAGLKTGIIRSMGGTGKVVTNAGLVFAFTMASMV MMAR_0255|M.marinum_M GSDYNLLLVSRFKQEIPAGINTGIIRSMGGTGKVVTNAGLVFAFTMASMV MAB_4116c|M.abscessus_ATCC_199 GSDYNLLLVSRMKEELGAGLKTGIIRAMGGTGKVVTAAGLVFAATMGSMI TH_3056|M.thermoresistible__bu GSDYNLMLVSRMKEEIGAGLNTGIIRAMGGTGRVVTMAGLVFAATMASMI MAV_3249|M.avium_104 GSDYNLLLVSRMKEEISAGINTGIIRAMGGTGKVVTNAGLVFAFTMASMV Mflv_3435|M.gilvum_PYR-GCK GADYNLLLVSRLKEEIHAGIGTGIIRAMGGSGSVVTAAGLVFALTMMSMS Mvan_3189|M.vanbaalenii_PYR-1 GADYNLLLVSRLKEEIHAGIGTGIIRAMGGSGSVVTAAGLVFALTMMSMA MUL_0757|M.ulcerans_Agy99 GADYNLLLVARLKEEIHAGINTGIIRAMGGSGSVVTAAGLVFAFTMMSFA MSMEG_3496|M.smegmatis_MC2_155 GADYNLLLVSRIKEEIHAGLNTGIIRSMGGTGSVVTSAGLVFAFTMMSMA *:****:**:*:*:*: **: *****:***:* *** ****** ** *: Mb0458c|M.bovis_AF2122/97 VSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAALLGRWFWWPLRVRSR Rv0450c|M.tuberculosis_H37Rv VSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAALLGRWFWWPLRVRSR MLBr_02378|M.leprae_Br4923 VSDLRVIGQVGTTIGLGLLFDTLIVRSFMMPSIAALLGRWFWWPQQGRTR MMAR_0255|M.marinum_M VSDVRMIGQVGTTIGLGLLFDTLVVRAFMTPAIAALLGRWFWWPLRVRSR MAB_4116c|M.abscessus_ATCC_199 VSDLLTIGQVGTTIGLGLLFDTLIVRAFMTPAIAALLGRWFWWPLQVSPR TH_3056|M.thermoresistible__bu VSDLLMIGQVGTTIALGLLFDTMVVRAFMTPSVAAILGRWFWWPQRVRTR MAV_3249|M.avium_104 VSDLRIIGQVGTTIGLGLMFDTLIVRSFMTPTIAALLGRWFWWPQLVRRR Mflv_3435|M.gilvum_PYR-GCK VSELTVIGQVGTTIGLGLLFDTLVIRAFMTPSIAALLGPWFWWPQRVRTR Mvan_3189|M.vanbaalenii_PYR-1 VSELTVIGQVGTTIGLGLLFDTLVIRAFMTPSIAALLGPWFWWPQRVRTR MUL_0757|M.ulcerans_Agy99 VSELTVMAQVGTTIGMGLLFDTLIVRSFMTPSIAALLGKWFWWPQVVRQR MSMEG_3496|M.smegmatis_MC2_155 VSELAVIAQVGTTIGLGLLFDTLVIRSFMTPSIAALMGKWFWWPQRVRQR **:: :.******.:**:***:::*:** *::**::* ***** * Mb0458c|M.bovis_AF2122/97 P---ARTPTVPSETQPAGRPLAMSSDRLG------------- Rv0450c|M.tuberculosis_H37Rv P---ARTPTVPSETQPAGRPLAMSSDRLG------------- MLBr_02378|M.leprae_Br4923 P---LLTVAAPVGLPPD-RSLVYSD----------------- MMAR_0255|M.marinum_M PDRRAIQRAAQSDTEPAPVESAPATAGS-------------- MAB_4116c|M.abscessus_ATCC_199 P---VGAVRGWRGPR-LVRSVLQRN----------------- TH_3056|M.thermoresistible__bu P---ASAMLRPVGPRPLVRSLLLRD----------------- MAV_3249|M.avium_104 P---ASQLLRSEGTRRSVRVLLHQNDDADADTAEIPVPRPTA Mflv_3435|M.gilvum_PYR-GCK P---VPAPWPRSGGLQSDPSEGVRA----------------- Mvan_3189|M.vanbaalenii_PYR-1 P---VPAPWPRPGGLQSDPSEGVKV----------------- MUL_0757|M.ulcerans_Agy99 P---APQPWPTPAPTPPPATTSV------------------- MSMEG_3496|M.smegmatis_MC2_155 P---LPAPWPQPVQRDPEDALNRV------------------ *