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TPAHSAGRPFIARTIQKFSLPVILLWIALTVGANLLAPQLEEVAKEHSVSLSPSDAPSLIAMRRIGKDFQ QFDSDNTTMIVLESNAKLGDEAHRYYDALIAKLSQDKTNIQHIDNFWGDRLTAAGSQSVDGKAAYVQLYL TGGLGSARANDSVAAVARILDDVPPPPGIKAYLTGPGALGADQDTSGNSSLQRLTAVTIAVITIVLLIAY RSIAAVVVMLLTVGIELLAARGVIAALAANDLIGLSTFAINVLTALTIAASTDYIIFLVGRYQEARMAGQ DRELAYYTMFRGTSHVVLGSGLTVAGAMYCLSFTRLPYFQTLGSPCSIGLLAVILASLTLAPAVIALTTK FGVFEPKRATTTRRWRRIGTIVVRWPGPVLVAAALISLIGLLALPKYQTNYNERHYIPAGAPSNIGYRAS DRHFPPARMEPEVLMIEADHDLRNPTDMMLLDRIAKGVFHLPGIARVQGITRPLGSPLDHSSIPFQLNMQ NAMTIENMGYLKARVADMYTMIDELQHMIDIAARQQELTQQLNDASHDMLTHNKQMQANTDQLRDQIAEF DDLWRPIRSYFYWERHCSDIPICWSLRSLFDAIDGVDKLSEDVGTLTDDLDRIDELQPKLLALLPPMIAT MQTVKSLTQTTASTFSALITQMDDMTRNATAMGQALDASKNDDSFYLPPEAFDNPDFQRGLTLFLSPDGT AARFIITHKGDPATAEGIAHIDPILLAASEAVKGTPLAAANIYLAGTAATYKDISEGSTYDLLIAVVATL CLIFVVMLAITRSVVASAVIVGTVALSLGAAFGLSVLLWQHILHMPLHWLVLPMAVIVMLAVGSDYNLLL VARFQEEIGAGLKTGMIRAMASTGRVVTIAGLVFAFTMGSMLTSDLRVVGQVGTTIMIGLLFDTLVVRSF MMPAIAALLGRWFWWPRRVPTHAASPPAVTASPGAAATSVLA*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_1722 | mmpL1_1 | - | 100% (953) | transmembrane transport protein MmpL1_1 |
M. marinum M | MMAR_0704 | mmpL1 | 0.0 | 75.35% (929) | transmembrane transport protein MmpL1 |
M. marinum M | MMAR_0775 | - | 0.0 | 61.74% (933) | MmpL family transport protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0458c | mmpL4 | 0.0 | 60.09% (932) | transmembrane transport protein MmpL4 |
M. gilvum PYR-GCK | Mflv_4418 | - | 0.0 | 58.67% (929) | transport protein |
M. tuberculosis H37Rv | Rv0402c | mmpL1 | 0.0 | 75.35% (925) | transmembrane transport protein MmpL1 |
M. leprae Br4923 | MLBr_02378 | - | 0.0 | 57.86% (935) | hypothetical protein MLBr_02378 |
M. abscessus ATCC 19977 | MAB_3150 | - | 0.0 | 56.33% (932) | MmpL family protein |
M. avium 104 | MAV_3863 | - | 0.0 | 57.72% (946) | MmpL4 protein |
M. smegmatis MC2 155 | MSMEG_3496 | - | 0.0 | 57.52% (944) | MmpL4 protein |
M. thermoresistible (build 8) | TH_3260 | - | 0.0 | 53.81% (946) | PUTATIVE MmpL4 protein |
M. ulcerans Agy99 | MUL_3688 | mmpL4_1 | 0.0 | 57.59% (936) | transmembrane transport protein MmpL4_1 |
M. vanbaalenii PYR-1 | Mvan_1936 | - | 0.0 | 58.45% (929) | transport protein |
CLUSTAL 2.0.9 multiple sequence alignment Mb0458c|M.bovis_AF2122/97 -------MSTKFAN-----------DSNTNARPEKPFIARMIHAFAVPII MLBr_02378|M.leprae_Br4923 -------MTVKCAN-----------DLDTHTKP--PFVARMIHRFAVPII Mflv_4418|M.gilvum_PYR-GCK --------MADAG---------------------RSGIGRIIRVLAVPIV Mvan_1936|M.vanbaalenii_PYR-1 --------MADAG---------------------RSGIGRIIHLLAVPIV MSMEG_3496|M.smegmatis_MC2_155 --------MSNP----SHDAPTDAMGVSGPKHARPGGIAKWIRVLAVPII TH_3260|M.thermoresistible__bu -------MTANPGHVRTDEAPTDRLDIKVSTHG-PSFISTWIRRLSLPII MAV_3863|M.avium_104 -------MTTDQAT--------------------RSVVAQTIRRLSVPIL MAB_3150|M.abscessus_ATCC_1997 -------MRHGSGD----------------HTARPPRIARLIRTLSIPII MUL_3688|M.ulcerans_Agy99 MSESNSGASISTEDTGPIEIGAATGGAPNRERGHRPVIPHTIRILAVPII MMAR_1722|M.marinum_M -------MTPAHSA------------------GRP-FIARTIQKFSLPVI Rv0402c|M.tuberculosis_H37Rv -------MRSQRLA------------------GHLSAAARTIHALSLPII *: :::*:: Mb0458c|M.bovis_AF2122/97 LGWLAVCVVVTVFVPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKEGD MLBr_02378|M.leprae_Br4923 LVWLAIAVTVSVFIPSLEDVGQERSVSLSPKDAPSYIAMQKMGQVFNEGN Mflv_4418|M.gilvum_PYR-GCK LGWVLLTVLTNVAVPSLEKVGEEHTVGMSAGDAPSMMSMKRVGANFEEFD Mvan_1936|M.vanbaalenii_PYR-1 LGWIALTVLTNVAVPSLEKVGEEHTVGMSANDAPSMMSMERVGANFDEFD MSMEG_3496|M.smegmatis_MC2_155 LVWVAIIAVLNTVVPQLDVVGEMRSVSMSPDDAPSVIAMKRVGEVFEEFK TH_3260|M.thermoresistible__bu VGWIALIALLNITVPQLEVVGEMRAVSMSPDEAPSMVAMKRVGELFDEGS MAV_3863|M.avium_104 LVWVAVAAISNIAVPNLEDVAKAHNVSLNTPAAPSFQAMQHIGKVFHEYD MAB_3150|M.abscessus_ATCC_1997 LFWLGIAIVLNIVTPSLDEVGKAHSVSMSPKDAPSMIAMMHTGKVFGEFD MUL_3688|M.ulcerans_Agy99 LGWVLLTVLVNVVVPSLEVVSEQHSAPMTPMDAPSMKAMMRLGHNFREFD MMAR_1722|M.marinum_M LLWIALTVGANLLAPQLEEVAKEHSVSLSPSDAPSLIAMRRIGKDFQQFD Rv0402c|M.tuberculosis_H37Rv LFWVALTIVVNVVAPQLQSVARTHSVALGPHDAPSLIAMKRIGKDFQQFD : *: : . *.*: *.. : . : . *** :* : * * : . Mb0458c|M.bovis_AF2122/97 SDSFAMVIIEGNQPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDPLTA MLBr_02378|M.leprae_Br4923 SDSVIMIVLEGDKPLGDDAHRFYDGLIRKLRADK-HVQSVQDFWGDPLTA Mflv_4418|M.gilvum_PYR-GCK SDSSAMVVLEGEQPLGDAAHRYYDQLIDELEADTANVQHIADFWGDPLTA Mvan_1936|M.vanbaalenii_PYR-1 SDSSAMVVLEGEQPLGDAAHRYYDELIGKLEADTANVQHVADFWGDPLTA MSMEG_3496|M.smegmatis_MC2_155 SNSSVMIVLEGEQPLGDEAHKYYDEIVDKLEADPAHVEHVQDFWGDPLTA TH_3260|M.thermoresistible__bu SDSQVMIVLEGEEPLGADARAFYDELVKRLEADDAHVENVQDLWSDPLTA MAV_3863|M.avium_104 SDSAAMIVLEGDKPLGDDAHRFYDALVGKLEHDTKHVEHVQNFWGDPLTA MAB_3150|M.abscessus_ATCC_1997 SDSSVMIVLEGQQELADEAHRFYDEIIKKLKADPTHIQHISDYWGDPLTA MUL_3688|M.ulcerans_Agy99 SNSTVMIVLEGQHKLGDDAHQYYDSLIRQLRQDPEHIQHIQDFWGDRLTA MMAR_1722|M.marinum_M SDNTTMIVLESNAKLGDEAHRYYDALIAKLSQDKTNIQHIDNFWGDRLTA Rv0402c|M.tuberculosis_H37Rv SDTTAMVLLEGQEKLGDEAHRFYDVLVTKLSQDTTHVQHIENFWGDPLTA *:. *:::*.: *. *: :** :: .* * ::: : : *.* *** Mb0458c|M.bovis_AF2122/97 AGVQSNDGKAAYVQLSLAGNQGTPLANESVEAVRSIVESTP---APPGIK MLBr_02378|M.leprae_Br4923 PGAQSNDGKAAYVQLSLAGNQGELLAQESIDAVRKIVVQTP---APPGIT Mflv_4418|M.gilvum_PYR-GCK SGAQSTDGKAAYVQVYLQGNQGEPRANEAVAAVREIVDRTP---APPGIK Mvan_1936|M.vanbaalenii_PYR-1 SGAQSTDGKAAYVQVYLQGNQGEPRANEAVAAVREIVDQTP---APPGLK MSMEG_3496|M.smegmatis_MC2_155 SGAQSPDGLASYVQVYTRGNQGEALANESVEAVQDIVESVP---APPGVK TH_3260|M.thermoresistible__bu TGVQSPDGKSAYVQVKLAGNQGEALANESVETVREMIATVSEEMAPEGVQ MAV_3863|M.avium_104 AGSQSKDGKAAYVQVYLAGNQGDALANESVDAIRNIVEHTP---PPPGVK MAB_3150|M.abscessus_ATCC_1997 SGAQSADGKSAYVQVNLAGDQGTTLANESVDAVRKIIAETP---GPAGVQ MUL_3688|M.ulcerans_Agy99 AGAQSADGKSAYVMVNLAGNQGTTLANESVEAVRDVINRTH---EPAGVK MMAR_1722|M.marinum_M AGSQSVDGKAAYVQLYLTGGLGSARANDSVAAVARILDDVP---PPPGIK Rv0402c|M.tuberculosis_H37Rv AGSQSADGKAAYVQLNLTGDQGGSQANESVAAVQRIVDSVP---PPPGIK .* ** ** ::** : *. * *:::: :: :: . * *: Mb0458c|M.bovis_AF2122/97 AYVTGPSALAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSIITVVLLL MLBr_02378|M.leprae_Br4923 AWVTGASALIADMHHSGDKSMIRITATSVIVILVTLLLVYRSFITVILLL Mflv_4418|M.gilvum_PYR-GCK AYVTGGAPLVADQHSAGDTSVLRVTLITIGVIAVMLLIVFRSVATMVLIL Mvan_1936|M.vanbaalenii_PYR-1 AYVTGGAPLVADQHNAGDKSVFRVTLITIGVIAVMLLLVFRSVATMVLIL MSMEG_3496|M.smegmatis_MC2_155 AYVTGPAALSADQHVASDRSVRVIEALTFAVIITMLLLVYRSIVTVILTL TH_3260|M.thermoresistible__bu AFVTGGAAMSADQQEAGDSSLRVIEALTFLVITTMLLFVYRSVITVLIAL MAV_3863|M.avium_104 AYVTGAAPLVTDQFEVGSKGIFKVTVITVLVILAMLLWVYRS-VTAVFVL MAB_3150|M.abscessus_ATCC_1997 AYVTGGTAASADTGTAGNKSMQKTTLIAVGVVLLMLLLVYRSVITTIVAL MUL_3688|M.ulcerans_Agy99 AYVTGPAALSDDMHLIGNASLATITMFTLGAIAVMLLLVYRSIVTTVIQL MMAR_1722|M.marinum_M AYLTGPGALGADQDTSGNSSLQRLTAVTIAVITIVLLIAYRSIAAVVVML Rv0402c|M.tuberculosis_H37Rv AYVTGPGPLGADRVVYGDRSLHTITGISIAVIAIMLFIAYRSLSAALIML *::** . * .. .: :. .: *: .:** : :. * Mb0458c|M.bovis_AF2122/97 ITVGVELTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFIIG MLBr_02378|M.leprae_Br4923 FTVGIESAVARGVVALLGHTGLIGLSTFAVNLLTSLAIAAGTDYGIFITG Mflv_4418|M.gilvum_PYR-GCK FMVFAELGAARGIVAFLADAEIIGLSTFATSLLTLMVIAAGTDYAIFAIG Mvan_1936|M.vanbaalenii_PYR-1 FMVFAELGAARGIVAFLANAEIIGLSTFATSLLTLMVIAAGTDYAIFAIG MSMEG_3496|M.smegmatis_MC2_155 VMVVLSLSAARGMIAFLGYHEIIGLSVFATNLLTTLAIAAATDYAIFLIG TH_3260|M.thermoresistible__bu FMVLIGLLTTRGVVAFLGYHNIIGLSTFATSLLVTLAIAIAVDYAIFLIG MAV_3863|M.avium_104 VTVIVEMAAARGIVAFLGSVGLIGLSTYATNLLTLLVIAAGTDYAIFFVG MAB_3150|M.abscessus_ATCC_1997 LIVGLELMAGQGVVATLGNLNVIGLSTYAVSMVTMLGIAAGTDYVIFLLG MUL_3688|M.ulcerans_Agy99 FMTGIALASSRGVVAVLGYHNVFGLTTFAANILTMLAIAAGTDYGIFLVG MMAR_1722|M.marinum_M LTVGIELLAARGVIAALAANDLIGLSTFAINVLTALTIAASTDYIIFLVG Rv0402c|M.tuberculosis_H37Rv LTVGLELLAVRGIISTFAVNDLMGLSTFTVNVLVALTIAASTDYIIFLVG . . :*::: :. :**:.:: .::. : ** ..** ** * Mb0458c|M.bovis_AF2122/97 RYQEARQAGEDKEAAYYTMYRGTAHVILGSGLTITGATFCLSFARMPYFQ MLBr_02378|M.leprae_Br4923 RYQEARQANENKEAAFYTMYRGTFHVILGSGLTISGATFCLSFARMPYFQ Mflv_4418|M.gilvum_PYR-GCK RYQEARGAGEDRETAYYTMFRGTAHVVLGSGLTIAGAMLCLSFTRLPYFQ Mvan_1936|M.vanbaalenii_PYR-1 RYQEARGAGEDRETAYYTMFRGTAHVVLGSGLTIAGAMLCLSFTRLPYFQ MSMEG_3496|M.smegmatis_MC2_155 RYQEARSVGEDREQSYYTMFHSTAHVVLGSGMTIAGATLCLHFTRMPYFQ TH_3260|M.thermoresistible__bu RYQEARSVGADRATAYHTMFGGTAHVILASGLTIAGATFCLSFTRLPYFQ MAV_3863|M.avium_104 RYHEARHEGQDRETAYYTMYRGTTHVVLGSGLTVAGAVLCLRFTRLNYFQ MAB_3150|M.abscessus_ATCC_1997 RYHEARHRGQDREAAFYTAYSGVSHVILGSGLTIVGATLCLSLTRLPLFR MUL_3688|M.ulcerans_Agy99 RYQEARQAGEDRQDAYYTTFRGVAPVVLGSGLTIAGATYCLSFARLPWFN MMAR_1722|M.marinum_M RYQEARMAGQDRELAYYTMFRGTSHVVLGSGLTVAGAMYCLSFTRLPYFQ Rv0402c|M.tuberculosis_H37Rv RYQEARATGQNREAAYYTMFGGTAHVVLASGLTVAGAMYCLGFTRLPYFN **:*** . :: :::* : .. *:*.**:*: ** ** ::*: *. Mb0458c|M.bovis_AF2122/97 TLGIPCAVGMLVAVAVALTLGPAVLHVGSRFG-LFDPKRLLKV-RGWRRV MLBr_02378|M.leprae_Br4923 TLGVPCAVGMLIAVAVALTLGPAVLTVGSRFG-LFEPKRLIKV-RGWRRI Mflv_4418|M.gilvum_PYR-GCK TMGVPCAVGTFVAVIAALTLGPAVIVIGSRFG-LFDPKRAISS-RGWRRI Mvan_1936|M.vanbaalenii_PYR-1 TMGVPCAVGTFVAVMAALTLGPAVVAIGSRFG-LFDPKRAISS-RGWRRI MSMEG_3496|M.smegmatis_MC2_155 SLGIPLAIGMSVVVLASLTMGAAIISVASRFGKTFEPKRAMRT-RGWRKL TH_3260|M.thermoresistible__bu SLGPPLAIGMIVLIVTSLTMGPAIITVATRFG-LLEPKRAARV-RFWRKV MAV_3863|M.avium_104 SLGIPAAIGIGVALAAALSLTPAVITVGSLFG-LFDPKRQMAT-RGWRRI MAB_3150|M.abscessus_ATCC_1997 SMGVPCALVILVIVAAALTLAPAILALGSRFG-LFEPKRKYDE-GGWRRI MUL_3688|M.ulcerans_Agy99 TMGAPVAIGMLVVVLAGLTLGPAVVFVGSRFH-PFESKRAANRGRLWRRV MMAR_1722|M.marinum_M TLGSPCSIGLLAVILASLTLAPAVIALTTKFG-VFEPKRATTT-RRWRRI Rv0402c|M.tuberculosis_H37Rv TLASPCAIGLVTVMLASLTLAPAIIAVASRFG-LFDPKRATTK-RRWRRI ::. * :: : ..*:: .*:: : : * ::.** **:: Mb0458c|M.bovis_AF2122/97 GTVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPANQGYA MLBr_02378|M.leprae_Br4923 GTVVVRWPLPILITTCAIAMVGLLALPGYRTNYKDRAYLPASIPANQGFA Mflv_4418|M.gilvum_PYR-GCK GVSVVRWPGPVLAATLALALVGLVTLPGYKTNYDARDYLPEDIPANVGYA Mvan_1936|M.vanbaalenii_PYR-1 GVSVVRWPGPVLAATLALALVGLVALPGYKTNYDSRDYLPEDVPANVGYA MSMEG_3496|M.smegmatis_MC2_155 GAAVVRWPAPILVTTIALSVVGLLALPGYQTNYNDRRYLPQDLPANTGYA TH_3260|M.thermoresistible__bu GASVVRWPGPIMVTTVAVTLVGLLALPGYRTNYNDRNYLPASFPSNAGYE MAV_3863|M.avium_104 GTAIVRWPGPILVVATGVALVGLLALPGYRTNYDARPYMPASAPANTGYT MAB_3150|M.abscessus_ATCC_1997 GAAVVRWPGPILVVTCGIALVGLLTLPGYTPGYDDRQYMPDNVPSKVGYA MUL_3688|M.ulcerans_Agy99 GTAVVRWPAPILALSGAIVLVGMVALPGFKTSYNDRYYLPASAPSNLGEA MMAR_1722|M.marinum_M GTIVVRWPGPVLVAAALISLIGLLALPKYQTNYNERHYIPAGAPSNIGYR Rv0402c|M.tuberculosis_H37Rv GTVVVRWPGPVLAATLLIALIGLLALPKYQTNYNERYYIPSAAPSNIGYL *. :**** *:: : : ::*:::** : ..*. * *:* *:: * Mb0458c|M.bovis_AF2122/97 AADRHFSQARMKPEILMIESDHDMRNPADFLVLDKLAKGIFRVPGISRVQ MLBr_02378|M.leprae_Br4923 AADRHFPQARMKPEILMIESDHDMRNPADFLILDKLARGIFRVPGISRVQ Mflv_4418|M.gilvum_PYR-GCK VADQHFGSARMNPELLMVESDHDLRNPADFLVIDKIAKSVFRVPGVARVQ Mvan_1936|M.vanbaalenii_PYR-1 VADRHFGSARMNPELLMVESDHDLRNPADFLVIDKIAKAIFRVPGVARVQ MSMEG_3496|M.smegmatis_MC2_155 AADRHFSQARMNPELLMIESDHDLRNSADFLVVDRIAKRVFQVPGISRVQ TH_3260|M.thermoresistible__bu AAERHFDPARLNPELLLIESDHDLRNPADFLVIEKIAKAVFQVEGISRVQ MAV_3863|M.avium_104 AAERHFSQARLNPELLMIETDHDMRNPADMINLERVAKAIAHLPGIAQVQ MAB_3150|M.abscessus_ATCC_1997 AAERHFSPARMNPEMLMIEADHDLRDPSDMLVIDRIAKTAFHARGVGRVQ MUL_3688|M.ulcerans_Agy99 AADRHFSHARMNPDMLMVEAEHDMRNPADMLVLDKVAKNVIRTVGIAMIQ MMAR_1722|M.marinum_M ASDRHFPPARMEPEVLMIEADHDLRNPTDMMLLDRIAKGVFHLPGIARVQ Rv0402c|M.tuberculosis_H37Rv ASDRHFPQARMEPEVLMVEADHDLRNPTDMLILDRIAKTVFHTPGIARVQ .:::** **::*::*::*::**:*:.:*:: ::::*: : *:. :* Mb0458c|M.bovis_AF2122/97 AITRPEGTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQADEMATT MLBr_02378|M.leprae_Br4923 AITRPDGTAMDHTSIPFQISMQNAGQVQTMKYQKDRMNDLLRQAENMAET Mflv_4418|M.gilvum_PYR-GCK TITRPDGKPIKHTTIPFQMSMQGTTQRLNEKYLQDRMADMLVQADAMQTN Mvan_1936|M.vanbaalenii_PYR-1 TITRPDGKPIKHTTIPFQMSMRSTTSRLNEKYMQDRMADMLVQADAMQTN MSMEG_3496|M.smegmatis_MC2_155 AITRPQGTPIEHTSIPFQISMSGTTQMMNMKYMQDRMADMLVMADEMQKS TH_3260|M.thermoresistible__bu GITRPEGTPIEHSSIPFMISQQGTLQILNQQYMQDRMADMLVQADEMQLM MAV_3863|M.avium_104 SMTRPLGTPIEHTSLAFQISAGSIGSIENLQYQKERAEDLLKQADNLKDT MAB_3150|M.abscessus_ATCC_1997 AITRPLGTPIEHSSIPFQIGLQGAGQIQNMKYMKDRMADMLTMANQMGIL MUL_3688|M.ulcerans_Agy99 DITRPLGIPIQHSSIPFQNSMQSQTMMQNMAFLKERMADMTKMADEMQVL MMAR_1722|M.marinum_M GITRPLGSPLDHSSIPFQLNMQNAMTIENMGYLKARVADMYTMIDELQHM Rv0402c|M.tuberculosis_H37Rv SITRPLGAPIDHSSIPFQLGMQSTMTIENLQNLKDRVADLSTLTDQLQRM :*** * .:.*:::.* . . . : * *: : : Mb0458c|M.bovis_AF2122/97 IAVLTRMHSLMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDFWRPIR MLBr_02378|M.leprae_Br4923 IASMRRMHQLMALLTENTHHILNDTVEMQKTTSKLRDEIANFDDFWRPIR Mflv_4418|M.gilvum_PYR-GCK VDTMTRMQSLMGQMSATTHEMVLKTKKTEIDIIEVRDNLADFDDFFRPVR Mvan_1936|M.vanbaalenii_PYR-1 VDTMTKMQSLMTQMSAATHDMVTKTKKTAVDIVEVRDYLANLDDFVRPVR MSMEG_3496|M.smegmatis_MC2_155 VDTMEEMLKITREMSDTTHSMVGKMHGMVEDIKELRDHIADFDDFLRPIR TH_3260|M.thermoresistible__bu IDTMDKMIALMEEMVETTDNMVRDMDEMAAHVAEMRDSISEFDDFFRPIR MAV_3863|M.avium_104 IGILNQQYALQKQLAASTHDETQSFHDTIAIINDLRDKIANFDDFFRPVR MAB_3150|M.abscessus_ATCC_1997 IGTMERVYGMMRELTDIMHDMTGQMKEMQGKMHDMRDLMYTFDDFFRPIR MUL_3688|M.ulcerans_Agy99 IDTTERMYAVMRELDTTTTDMARVTAETSTITDELRDHLAEFDDFWRPMR MMAR_1722|M.marinum_M IDIAARQQELTQQLNDASHDMLTHNKQMQANTDQLRDQIAEFDDLWRPIR Rv0402c|M.tuberculosis_H37Rv IDITQRTQELTRQLTDATHDMNAHTRQMRDNANELRDRIADFDDFWRPLR : . : : .:** : :**: **:* Mb0458c|M.bovis_AF2122/97 SYFYWEKHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREMDRLMP MLBr_02378|M.leprae_Br4923 SYFYWERHCFNIPICWSFRSIFDALDGVDQIDERLNSIVGDIKNMDLLMP Mflv_4418|M.gilvum_PYR-GCK NYFYWEPHCYDIPVCWTMRSVFDTLDGINPLTDDISELIPDLERLDELMP Mvan_1936|M.vanbaalenii_PYR-1 NYFYWEPHCYNIPVCATMRSVFDTLDGINPLTDDIQELIPDLERLDALMP MSMEG_3496|M.smegmatis_MC2_155 NYFYWEPHCDSIPVCQSIRSIFDTLDGIDVMTDDIQRLMPDMDRLDELMP TH_3260|M.thermoresistible__bu NYFYWEPHCYNIPVCWAMRSVFDTLDGINTMTDDIQNMLPHMHRLNDLMP MAV_3863|M.avium_104 SYFYWEKHCFDIPACFAFRSVFDALDGIDELSAQFEKLTASLDKLDAGQQ MAB_3150|M.abscessus_ATCC_1997 NYFYWEKHCADIPICWASRTVFDALDGVDQITEDMDGMVVNVDKIDVLMP MUL_3688|M.ulcerans_Agy99 SYFYWEKHCFDVPICWSFRSLFDSLDGIDKLSEKFSELTEDIQRTAGLTS MMAR_1722|M.marinum_M SYFYWERHCSDIPICWSLRSLFDAIDGVDKLSEDVGTLTDDLDRIDELQP Rv0402c|M.tuberculosis_H37Rv SFTYWERHCFDIPICWSMRSLLNSMDNVDKLTEDLANLTDDTERMDTTQR .: *** ** .:* * : *::::::*.:: : . : . Mb0458c|M.bovis_AF2122/97 QMVAQIPPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMGKAFDA MLBr_02378|M.leprae_Br4923 QMLEQFPPMIESMESMRTIMLTMHSTMSGIFDQMNELSDNANTMGKAFDT Mflv_4418|M.gilvum_PYR-GCK QLIALLPSQIETMRSMQAMMLRQYQTQKGQLDQNAAMSEDADAMGEAFDD Mvan_1936|M.vanbaalenii_PYR-1 QLIALLPSQIESMRNMQSMMLTMYQSQKGLQDQMASQSEDADAMGEAFDD MSMEG_3496|M.smegmatis_MC2_155 QMLTIMPPMIESMKTMKTMMLTTQATMGGLQDQMEAAMENQTAMGQAFDA TH_3260|M.thermoresistible__bu QMLTLLPTTVATMKTMRSMLLTMQATNAGLQDQMAEMQENANAMGEAFDQ MAV_3863|M.avium_104 KLVTLLPPQIADQEKNLALTLSNYATNLGINAQTRANTDTATALGQAYDA MAB_3150|M.abscessus_ATCC_1997 RVLAEFPPMIAIMKTMHGSLLTMHSTMAGIMNQMDESTKNSTLMGKYFDE MUL_3688|M.ulcerans_Agy99 QMLTLIPPMIATMKTTKALTLTMQSTFSAMLDQMDELSNTAIVMGQSFDA MMAR_1722|M.marinum_M KLLALLPPMIATMQTVKSLTQTTASTFSALITQMDDMTRNATAMGQALDA Rv0402c|M.tuberculosis_H37Rv QLLAQLDPTIATMQTVKDLAQTLTSAFSGLVTQMEDMTRNATVMGRTFDA ::: : . : .. : . * :*. * Mb0458c|M.bovis_AF2122/97 AKNDDSFYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQSPEGI MLBr_02378|M.leprae_Br4923 AKNDDSFYLPPEVFKNTDFKRAMKSFLSSDGHAARFIILHRGDPASVAGI Mflv_4418|M.gilvum_PYR-GCK SMNDDSFYLPPEAFDNDDFKRGMENFISPDGRSVRFIISHEGDPATVEGI Mvan_1936|M.vanbaalenii_PYR-1 SMNDDSFYLPPEAFDNDDFKRGIENFISPDGKSVRFIIAHEGDPATVEGI MSMEG_3496|M.smegmatis_MC2_155 SKNDDSFYLPPETFENPDFKRGMKMFLSPDGHAVRFIISHEGDPMSPEGI TH_3260|M.thermoresistible__bu ARNDDSFYLPPEAFDNPDFQRGLEQFLSPDGHAVRFIISHQGDPMTPEGL MAV_3863|M.avium_104 AKNDDSFYLPPEAFTNPEFKRGLKLFLSPDGKAARMIISHEGDPATPEGI MAB_3150|M.abscessus_ATCC_1997 AKNDDSFYLPPEVFDNPDFKRGLKMFLSPDGKAVRMTVSHQGNPASVQGI MUL_3688|M.ulcerans_Agy99 SKNDDFFYLPPEAFDNPDFQTGLRMFLSPDGKSARFFITHQGDPMTPEGI MMAR_1722|M.marinum_M SKNDDSFYLPPEAFDNPDFQRGLTLFLSPDGTAARFIITHKGDPATAEGI Rv0402c|M.tuberculosis_H37Rv ANNDDSFYLPPEAFQNPDFQRGLKLFLSPDGTCARFVITHRGDPASAEGI : *** ******.* * :*: .: *:*.** ..*: : *.*:* : *: Mb0458c|M.bovis_AF2122/97 KSIDAIRTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAIS MLBr_02378|M.leprae_Br4923 ASINAIRTAAEEALKGTPLEDTKIYLAGTAAVFKDIDEGANWDLVIAGIS Mflv_4418|M.gilvum_PYR-GCK SEVVPIKTAAKEAIKGTPLEGSTVYLAGTAATYKDMSDGAFYDLLIAGIA Mvan_1936|M.vanbaalenii_PYR-1 SRVLPIKTAAKEAIKGTPLEGSTVYLAGTAATYKDMRDGANYDLLIAGIA MSMEG_3496|M.smegmatis_MC2_155 KHIDAIKQAAKEAIKGTPLEGSKIYLGGTAATFKDLQEGANYDLIIAGIA TH_3260|M.thermoresistible__bu AKIEPIKKAAVEAIKGTPLEGSRVYLGGTAAVFKDMSDGTKYDLIIAAIA MAV_3863|M.avium_104 SHIEPIRNAAKQAVKNTPLGDSNIYLAGTAATYKDIAEGAKYDLLIAGIA MAB_3150|M.abscessus_ATCC_1997 ETVGNIREAVADAIKGTPLENAKVYMGGTAATNRDLQEGAKYDLILAGIA MUL_3688|M.ulcerans_Agy99 SRVDAERTAAQEGLKQSSLSDAKVYLGGTAATFKDMADGEKYDLMIAVVS MMAR_1722|M.marinum_M AHIDPILLAASEAVKGTPLAAANIYLAGTAATYKDISEGSTYDLLIAVVA Rv0402c|M.tuberculosis_H37Rv SHIDPIMQAADEAVKGTPLQAASIYLAGTSSTYKDIHEGTLYDVMIAVVA : *. :.:* :.* : :*:.**::. :*: :* :*:::* :: Mb0458c|M.bovis_AF2122/97 SLCLIFIIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHILAIHLH MLBr_02378|M.leprae_Br4923 SLCLIFIIMLIITRAFVAAAVIVGTVALSLGASFGLSVLLWQHILGIELH Mflv_4418|M.gilvum_PYR-GCK AVTLIFVIMLVITRSVVAAAVIVGTVLLSLGASFGLSVLLWQHIIGLALH Mvan_1936|M.vanbaalenii_PYR-1 AVTLIFVIMLIITRSVVAAAVIVGTVLLSLGASFGLSVLLWQHIIGLALH MSMEG_3496|M.smegmatis_MC2_155 ALCLIFIIMLIITRAVVASAVIVGTVVISLGASFGLSVLIWQHIIGLELH TH_3260|M.thermoresistible__bu AVCLIFIIMLILTRAVVAAAVIVGTVTLSLAASFGVSVLIWQYIVGLEMH MAV_3863|M.avium_104 ALSLILLIMVLITRSLVAAIVIVGTVALSLGASFGLSVLVWQDILGIKLY MAB_3150|M.abscessus_ATCC_1997 SLCLIFIIMLLVTGSVVAALVIVGTVAVSLGASVGVSVLIWQDLLGMDLH MUL_3688|M.ulcerans_Agy99 ALTLIFLIMLLLTRSVVAALVIVGTAASSIAASFGLSVLIWQDLFGIKIH MMAR_1722|M.marinum_M TLCLIFVVMLAITRSVVASAVIVGTVALSLGAAFGLSVLLWQHILHMPLH Rv0402c|M.tuberculosis_H37Rv SLCLIFIIMLGITRSVVASAVIVGTVALSLGSAFGLSVLIWQHILHMPLH :: **:::*: :* :.:*: *****. *:.::.*:***:** :. : :: Mb0458c|M.bovis_AF2122/97 WLVLAMSVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVVT MLBr_02378|M.leprae_Br4923 YLVLAMSVIVLLAVGSDYNLLLVSRFKQEIQAGLKTGIIRSMGGTGKVVT Mflv_4418|M.gilvum_PYR-GCK WMVLPMAVILLLAVGSDYNLLLVSRFKEELSGGLKTGIIRAMAGTGSVVT Mvan_1936|M.vanbaalenii_PYR-1 WMVLPMAVILLLAVGSDYNLLLVSRFKEELAGGLKTGIIRSMAGTGSVVT MSMEG_3496|M.smegmatis_MC2_155 WMVLAMAVIVLLAVGADYNLLLVSRIKEEIHAGLNTGIIRSMGGTGSVVT TH_3260|M.thermoresistible__bu WMVFPMALIILLAVGADYNLLVVARLREEIPAGLNTGMIRAMGGSGSVVT MAV_3863|M.avium_104 WICLALSVIILLAVGSDYNLLLISRFREEIHAGLNTGIIRSMAGSGAVVT MAB_3150|M.abscessus_ATCC_1997 WFVVPLSVIILLAVGSDYNLLLIARFKEELHGGLKTGFIRAMGGSGKVVT MUL_3688|M.ulcerans_Agy99 WIVAALSVIILLAVGSDYNLLLVSRFREEIHAGLKTGIIRSMAGTGGVVT MMAR_1722|M.marinum_M WLVLPMAVIVMLAVGSDYNLLLVARFQEEIGAGLKTGMIRAMASTGRVVT Rv0402c|M.tuberculosis_H37Rv WLVLPMAIIVMLAVGSDYNLLLIARFQEEIGAGLKTGMIRAMAGTGRVVT :: .:::*::****:*****:::*:::*: .**:**:**:*..:* *** Mb0458c|M.bovis_AF2122/97 NAGLVFAVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAAL MLBr_02378|M.leprae_Br4923 NAGLVFAFTMASMVVSDLRVIGQVGTTIGLGLLFDTLIVRSFMMPSIAAL Mflv_4418|M.gilvum_PYR-GCK SAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVRSFMTPAVAAL Mvan_1936|M.vanbaalenii_PYR-1 SAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVRSFMTPAVAAL MSMEG_3496|M.smegmatis_MC2_155 SAGLVFAFTMMSMAVSELAVIAQVGTTIGLGLLFDTLVIRSFMTPSIAAL TH_3260|M.thermoresistible__bu AAGLVFGLTMMVMVVSDLTVMGQVGTTIGLGLLFDTFVVRSFMMPSIATL MAV_3863|M.avium_104 SAGLVFAFTMASFVSASLLVLGQIGTTIALGLLFDTLIVRSFMTPSVAAL MAB_3150|M.abscessus_ATCC_1997 NAGLVFAFTMCAMVVSDLRIVGQLGTTIGLGLLFDTLIVRSFMMPSIAAL MUL_3688|M.ulcerans_Agy99 AAGLVFAFTMASMLGSDLRVLGQFGSTVCIGLLLDTLIVRTLLMPSIATL MMAR_1722|M.marinum_M IAGLVFAFTMGSMLTSDLRVVGQVGTTIMIGLLFDTLVVRSFMMPAIAAL Rv0402c|M.tuberculosis_H37Rv IAGLVFAFTMGSMVASDLRVVGQIGTTIMIGLLFDTLVVRSYMTPALATL *****..** : :.* ::.*.*:*: :***:**:::*: : *::*:* Mb0458c|M.bovis_AF2122/97 LGRWFWWPLRVRSRPARTPTVPSETQPAGRPLAMSSDRLG---------- MLBr_02378|M.leprae_Br4923 LGRWFWWPQQGRTRPLLTVAAPVGLPPD-RSLVYSD-------------- Mflv_4418|M.gilvum_PYR-GCK LGRWFWWPQKFRSAASERRLARIGVQPATAGR------------------ Mvan_1936|M.vanbaalenii_PYR-1 LGRWFWWPQKVRSHASQRRLAALNH------------------------- MSMEG_3496|M.smegmatis_MC2_155 MGKWFWWPQRVRQRPLPAPWPQPVQRDPEDALNRV--------------- TH_3260|M.thermoresistible__bu LGRWFWWPQFVRKRPVPQPWPSVPPRGP-ATTDRVSV------------- MAV_3863|M.avium_104 LGRWFWWPQRVRPRPASTMLRPYGPRPAVRQLLLWEDGDPAVAPETPSAA MAB_3150|M.abscessus_ATCC_1997 LGRWFWWPLRVRTHGTAGV------------------------------- MUL_3688|M.ulcerans_Agy99 LGRWFWWPQVVHPRGDNARPRVAAPTH----------------------- MMAR_1722|M.marinum_M LGRWFWWPRRVPTHAASP----PAVTASPGAAATSVLA------------ Rv0402c|M.tuberculosis_H37Rv LGRWFWWPRRVDRLARQPQVLGPRRTTALSAERAALLQ------------ :*:***** Mb0458c|M.bovis_AF2122/97 ----- MLBr_02378|M.leprae_Br4923 ----- Mflv_4418|M.gilvum_PYR-GCK ----- Mvan_1936|M.vanbaalenii_PYR-1 ----- MSMEG_3496|M.smegmatis_MC2_155 ----- TH_3260|M.thermoresistible__bu ----- MAV_3863|M.avium_104 RHSRG MAB_3150|M.abscessus_ATCC_1997 ----- MUL_3688|M.ulcerans_Agy99 ----- MMAR_1722|M.marinum_M ----- Rv0402c|M.tuberculosis_H37Rv -----