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NFSVLPPEINSLRIFAGTGSGPMLAAAAAWDGLADELSTAAAAFSSVTSGLTGGSWQGPAAAAMAAAAAP YAGWLGLAAARAGDVSAQAKVVAAAFEAVRAATVHPMLVAANRAQLVSLVRSNLLGLNAPAIATTEAEYE AMWAADVAAMVGYHGGASAAAAQLAPWQQWLQSLPGLPGQLAGSATAAAAANGWPNLGIGNTDSNVGSGD VGTQNLGSGNTGNTNLGSGNTGNGNLGSGNRGDSNVGSGNLGNSNWGSGNTGNYNQGSGNHGDNNVGFGN AGLGGTAGNDNFGNGNLGSGNTGSGNIGNQNQGWGNQGDNNVGLANRGSDNMGFGNTGNNNVGFGNTGSG NIGIGLTGNNQMGFGGLNSGSGNLGFGNSGTGNVGFFNSGVGNWGIGNSGAIDTGFGNSGFIDTGIGNSG ALNTGIGNSGLNAGSGFNVGFGNSGINNFGVGNSGSFNAGSFNSSTSNLGSFNSGNFVLGGFNVGSFNSG AHNTGAFNAGGYNTGFWNAGDINTGMWNSGDLNTGLGSAITQTVANSGFFNAGSTSSGLFNVGSGGHNSG FVNVGSGGYNSGFFNLGAGGSNAGFFNSGAGGGNTGLLNLGNGGNNTGFFNVGNGGYNTGFVNAGSDGSN AGFFTLGGYNSGVLNIGSLNSGVLNSGTANSGVPLILLLSLLSFVPLL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1550 | - | - | 100% (679) | PPE family protein |
| M. marinum M | MMAR_4320 | - | 0.0 | 58.04% (684) | PPE family protein |
| M. marinum M | MMAR_0926 | - | 0.0 | 52.53% (750) | PPE family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3184c | PPE70 | 0.0 | 57.50% (680) | PPE family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-33 | 26.64% (642) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv3159c | PPE53 | 0.0 | 57.92% (644) | PPE family protein |
| M. leprae Br4923 | MLBr_01182 | - | 2e-29 | 43.75% (160) | PPE-family protein |
| M. abscessus ATCC 19977 | MAB_4284c | - | 5e-29 | 28.95% (487) | hypothetical protein MAB_4284c |
| M. avium 104 | MAV_4704 | - | 2e-53 | 59.20% (174) | PPE family protein |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 4e-29 | 30.22% (556) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3569 | - | 1e-24 | 34.02% (194) | PUTATIVE PPE protein |
| M. ulcerans Agy99 | MUL_0964 | - | 0.0 | 54.68% (684) | PPE family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 3e-35 | 27.82% (683) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3184c|M.bovis_AF2122/97 --------------------------------------------------
Rv3159c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0964|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1550|M.marinum_M --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------------MMFLAPPG
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3569|M.thermoresistible__bu --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 --------------------------------------------------
Rv3159c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0964|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1550|M.marinum_M --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ---------------------------------------MVTFGGGATPT
Mvan_1264|M.vanbaalenii_PYR-1 GPGPISAAIQLTSTGSEATEP----------------WYVVSFGGSGAPT
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3569|M.thermoresistible__bu --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 --------------------------------------------------
Rv3159c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0964|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1550|M.marinum_M --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK PTSLGAA-------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 PNNLAAS-------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3569|M.thermoresistible__bu --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 --------------------------------------------------
Rv3159c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0964|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1550|M.marinum_M --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3569|M.thermoresistible__bu --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 ----------------------------------------MN---YSVLP
Rv3159c|M.tuberculosis_H37Rv ----------------------------------------MN---YSVLP
MUL_0964|M.ulcerans_Agy99 ----------------------------------------MN---FMMLP
MMAR_1550|M.marinum_M ----------------------------------------MN---FSVLP
MAV_4704|M.avium_104 ----------------------------------------MTNPHFAWLP
Mflv_5091|M.gilvum_PYR-GCK --------------------AVDLSGTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 --------------------LVDLSGTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
MLBr_01182|M.leprae_Br4923 ------------------------------------------MFDFAALS
MAB_4284c|M.abscessus_ATCC_199 --------------------------MSIIDFILNLFRDPVEAASYVADP
TH_3569|M.thermoresistible__bu ---------------------------------------MMTAPIWMALP
Mb3184c|M.bovis_AF2122/97 PEIN---SLRMFTGAGSAPMLAASVAWDGLAAELAVAASSFGSVTSGLAG
Rv3159c|M.tuberculosis_H37Rv PEIN---SLRMFTGAGSAPMLAASVAWDRLAAELAVAASSFGSVTSGLAG
MUL_0964|M.ulcerans_Agy99 PEVN---SALMFTGAGSAPTLAAATAWDGLVAELGEAAEAFSSVTSGLAS
MMAR_1550|M.marinum_M PEIN---SLRIFAGTGSGPMLAAAAAWDGLADELSTAAAAFSSVTSGLTG
MAV_4704|M.avium_104 PEVN---SALIYSGPGPGPLLAAAAAWDGLAEELASSAQSFSSVTSDLAS
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
MLBr_01182|M.leprae_Br4923 PETN---STRMYLGPGSSPILTAAAAWVVLAKELTAAAQGLQSAVEALLT
MAB_4284c|M.abscessus_ATCC_199 EAALANAGLSAVSAAQVGAVMPVVAESVASNYGYQSQWVNTGNPIHDLSG
TH_3569|M.thermoresistible__bu PEVH---SALLSSGPGPGSLLAAASAWHALSAEYASAAAELSSVLANVQA
. . .
Mb3184c|M.bovis_AF2122/97 QSWQG-AAAAMAAAAAPYAGWLAAAAARAAGASAQAKAVASAFEAARAAT
Rv3159c|M.tuberculosis_H37Rv QSWQGAAAAAMAAAAAPYAGWLAAAAARAAGASAQAKAVASAFEAARAAT
MUL_0964|M.ulcerans_Agy99 GSWQGPAAAAMAAAAAPYAGWLSAAATRALGAATQAKAAAAVFESAQAAT
MMAR_1550|M.marinum_M GSWQGPAAAAMAAAAAPYAGWLGLAAARAGDVSAQAKVVAAAFEAVRAAT
MAV_4704|M.avium_104 GSWQGASSAAMMTVANQYVSWLSAAAAQAEEVSHQASAIATAFEVALAAT
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
MLBr_01182|M.leprae_Br4923 -TFEGESAAALAERVTPYEKWLTQNAASAELTATQLTVAANAYETAFTMT
MAB_4284c|M.abscessus_ATCC_199 NLQNYYAAQPDGPSILSPSLLSPRDNDFLSHNDTDFASHNPIASGNQVMS
TH_3569|M.thermoresistible__bu GSWEGPSAERYVAAHAPYLAWLTQQSANSAATAGRHETAAAAYSTALATM
.
Mb3184c|M.bovis_AF2122/97 VHPMLVAANRNAFVQLVLSNLFGQNAPAIAAAEAMY------------EQ
Rv3159c|M.tuberculosis_H37Rv VHPMLVAANRNAFVQLVLSNLFGQNAPAIAAAEAMY------------EQ
MUL_0964|M.ulcerans_Agy99 VHPELVLANRNQLVSLVLSNLFGQNAPAIAATESTY------------EE
MMAR_1550|M.marinum_M VHPMLVAANRAQLVSLVRSNLLGLNAPAIATTEAEY------------EA
MAV_4704|M.avium_104 VQPAVVAANRALVQALAATNWLGQNTPAIADIEAAY------------EQ
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
MLBr_01182|M.leprae_Br4923 VPPLMVFVNRAQACLLIMSNIFGQNSTAIAEKEAEY------------TE
MAB_4284c|M.abscessus_ATCC_199 PSGNVDSFNRGPLLDLSFGDLQFGNRDTTAIGDGAV-------------A
TH_3569|M.thermoresistible__bu PTMAELTLNKTTHAVLVATNFLGINTIPIALNEADY------------VR
. . . .
Mb3184c|M.bovis_AF2122/97 MWAADVAAMVGYHGGASAAAAALPSWQQALRGLPGLGQVASAIS------
Rv3159c|M.tuberculosis_H37Rv MWAADVAAMVGYHGGASAAAAQLSSWSIGLQ-------------------
MUL_0964|M.ulcerans_Agy99 LWAQDVAATVGYHGGASAVAAQLAPWQQAIQALPGRVAAMATTG------
MMAR_1550|M.marinum_M MWAADVAAMVGYHGGASAAAAQLAPWQQWLQSLPGLPGQLAG--------
MAV_4704|M.avium_104 MWASDVAAMFGYHADASAAVAKLPPWNEVLQ-------------------
Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----AVGAAG------
Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----AIGTAG------
MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH
MLBr_01182|M.leprae_Br4923 MWIQDAAAMTSYQASVLEAVGATKAFTAPPLGVN----------------
MAB_4284c|M.abscessus_ATCC_199 VGGSNSGPIASGQGSTAVNGDVRDSNIINADHGSNVGVDQSQTR------
TH_3569|M.thermoresistible__bu MWIQAATSMSTYQAVAGTAVMSAPASSPAPLLLAP---------------
: .
Mb3184c|M.bovis_AF2122/97 --GGAASMFAAPAAATAAVTPPALNTG-----LGNIGSWNLGGGNVGLLN
Rv3159c|M.tuberculosis_H37Rv -----QALPAAPSALAAAIG------------LGNIGVGNLGGGNTGDYN
MUL_0964|M.ulcerans_Agy99 --PAASAAAALASGPAAALDIGNNGSGNFLS-IGNIGNNNLGSGNTGSAN
MMAR_1550|M.marinum_M ---SATAAAAANGWPNLGIGNTDSNVG-----SGDVGTQNLGSGNTGNTN
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -AAGTVGTAGATGGTGTGANGGAGGVG-----GVGGTGAAGAAGGAGGLG
Mvan_1264|M.vanbaalenii_PYR-1 -VAGAAGTAGATGGTGVGGNGGAGQAG-----GIGGTGAAGAAGQAGTAG
MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS
MLBr_01182|M.leprae_Br4923 ----------------------------------EVGLAQEVVEEVVEEV
MAB_4284c|M.abscessus_ATCC_199 -VGGDYTNVSGHGSADIDKSVTVVDDHS----QRNTTNINDSFNTDRSTN
TH_3569|M.thermoresistible__bu ----------------------------------------------GVSE
Mb3184c|M.bovis_AF2122/97 LGSGNFGSLNLG--------------------------------------
Rv3159c|M.tuberculosis_H37Rv LGSGNSGNANVG--------------------------------------
MUL_0964|M.ulcerans_Agy99 LGGGNIGNGNLG--------------------------------------
MMAR_1550|M.marinum_M LGSGNTGNGNLG--------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ETGTTGGAGGVG--------------------GQGTAGGTGGVGGIGGAG
Mvan_1264|M.vanbaalenii_PYR-1 ETGVTGGVGGIG--------------------GQGTEGGTGGVGGVGGVG
MSMEG_0868|M.smegmatis_MC2_155 TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIY
MLBr_01182|M.leprae_Br4923 VEEVVEAEQAIS--------------------------------------
MAB_4284c|M.abscessus_ATCC_199 IGSGNTTNTEIG--------------------------------------
TH_3569|M.thermoresistible__bu AADAMATTQQIG--------------------------------------
Mb3184c|M.bovis_AF2122/97 --------------------------------------------------
Rv3159c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0964|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1550|M.marinum_M --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------STGAVGG-------VGGKG----IQGGQG-----------
Mvan_1264|M.vanbaalenii_PYR-1 ----------ATGGAGG-------VGGKG----IQGGQG-----------
MSMEG_0868|M.smegmatis_MC2_155 SGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTA
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3569|M.thermoresistible__bu --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 ----GGNTGNANLGGGNWGFANLGSGN----------------IGNTNFG
Rv3159c|M.tuberculosis_H37Rv ----SGNSGNANVGSGNDGATNLGSGN----------------IGNTNLG
MUL_0964|M.ulcerans_Agy99 ----SGNTGNVNLGNGNNGFFNFGNGN----------------LGDTNFG
MMAR_1550|M.marinum_M ----SGNRGDSNVGSGNLGNSNWGSGN----------------TGNYNQG
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --LQGGKGGDGGAGGKGGDADSMGS------------------AGATGGK
Mvan_1264|M.vanbaalenii_PYR-1 --LQGGQGGDGGTGGTGGDATSMGE------------------AGATGGK
MSMEG_0868|M.smegmatis_MC2_155 KAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAV
MLBr_01182|M.leprae_Br4923 ---QAALDQAVNEGMEATVVPQVD--------------------------
MAB_4284c|M.abscessus_ATCC_199 ----SHNQANIGTSTSAGGSAAVGGNAG---------------LAGNAGL
TH_3569|M.thermoresistible__bu --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 NGNQGNLNFGSGNLL-----------------------------------
Rv3159c|M.tuberculosis_H37Rv SGNVGNVNLGSGNR------------------------------------
MUL_0964|M.ulcerans_Agy99 SGNSGNLNLGSGNRF-----------------------------------
MMAR_1550|M.marinum_M SGNHGDNNVGFGNAG-----------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GGNGGNGGRGGLFG---------------KGGNAGNGAD-----------
Mvan_1264|M.vanbaalenii_PYR-1 GGNGGNGGRGSLFG---------------RGGNAGNGGN-----------
MSMEG_0868|M.smegmatis_MC2_155 GGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGP
MLBr_01182|M.leprae_Br4923 --QQVNVDVATPQT------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AGNAGLAGNAGLAGN-----------------------------------
TH_3569|M.thermoresistible__bu --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 ----------GNGNFGFGNAFGDGNLGSGNVGSTNLGS------------
Rv3159c|M.tuberculosis_H37Rv ----------GFGNLGNGN-FGSGNLGSGNTGSTNFGG------------
MUL_0964|M.ulcerans_Agy99 ----------GSGNIGFGNRFGDGNFGSGNAGSYNFGT------------
MMAR_1550|M.marinum_M ----------LGGTAGNDN-FGNGNLGSGNTGSGNIGNQ-----------
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -----------GGTGGAGGAGGTGG-TGGAGGTGG---------------
Mvan_1264|M.vanbaalenii_PYR-1 -----------GGTGGNGGNGGTGG-TGGNGGTGG---------------
MSMEG_0868|M.smegmatis_MC2_155 AGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQ
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------AGLAGNAGLAGNAGLAGNAGLAGN---------------
TH_3569|M.thermoresistible__bu --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 -------GNFGSFNVGSGNMGMSNIGFGNLGNNNLGFGNNGNNNIGFGLT
Rv3159c|M.tuberculosis_H37Rv -------GNLGSFNLGSGNIGSSNIGFGNNGDNNLGLGNNGNNNIGFGLT
MUL_0964|M.ulcerans_Agy99 -------GNNGSFNIGSGNNGDSNIGFGNLGTNNLGFGNNGSNNIGFGLS
MMAR_1550|M.marinum_M ---NQGWGNQGDNNVGLANRGSDNMGFGNTGNNNVGFGNTGSGNIGIGLT
MAV_4704|M.avium_104 ---------------------------------NLGFSNAST-------A
Mflv_5091|M.gilvum_PYR-GCK --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKG
Mvan_1264|M.vanbaalenii_PYR-1 --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKG
MSMEG_0868|M.smegmatis_MC2_155 TDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGRG
MLBr_01182|M.leprae_Br4923 -------AVPDSSSAAAPQLWGGFAQHLSPINDTLSMINNHAGMANAGLS
MAB_4284c|M.abscessus_ATCC_199 ------AGLAGNAGLAGNAGLAGNAGLAG----NAGLAGNAGLAGNAGLA
TH_3569|M.thermoresistible__bu -------------SQATAADSGTALNLSDLIANLLQYYQDYLDQLFGPIV
Mb3184c|M.bovis_AF2122/97 GDNLVGIGALNSGIGNMGFGNSGNNNIGFFN--------------SGNGN
Rv3159c|M.tuberculosis_H37Rv GDNLVGIGALNSGIGNLGFGNSGNNNIGFFN--------------SGNNN
MUL_0964|M.ulcerans_Agy99 GSNQIGIGGLNAGIGNMGFGNAGDNNVGFFN--------------SGSNN
MMAR_1550|M.marinum_M GNNQMGFGGLNSGSGNLGFGNSGTGNVGFFN--------------SGVGN
MAV_4704|M.avium_104 VTRPAGSGAVARG--------YTSRIAGFLA--------------PRAPQ
Mflv_5091|M.gilvum_PYR-GCK GTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGGTGGTGG
MSMEG_0868|M.smegmatis_MC2_155 GDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNGG
MLBr_01182|M.leprae_Br4923 LVNGMGSAMKSLAPTTTKAAESAFKAMGSAVQS------------TGRGL
MAB_4284c|M.abscessus_ATCC_199 GNAGLAGNAGLAGNAGLAGNAGLAGNAGLAG---------------NAGL
TH_3569|M.thermoresistible__bu DFLRDPIGNLFQLIDDFLTNPAGALVTWWPL-------------------
Mb3184c|M.bovis_AF2122/97 VG------------------------------------------------
Rv3159c|M.tuberculosis_H37Rv VG------------------------------------------------
MUL_0964|M.ulcerans_Agy99 IG------------------------------------------------
MMAR_1550|M.marinum_M WG------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK AG-----------DGTGGTGGTGG----TGGQGGQGGQGG----------
Mvan_1264|M.vanbaalenii_PYR-1 AG-----------DGLGGTGGTGG----TGGFGGQGGQGG----------
MSMEG_0868|M.smegmatis_MC2_155 AGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVIG
MLBr_01182|M.leprae_Br4923 LG------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AG------------------------------------------------
TH_3569|M.thermoresistible__bu --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 -------FFNSGDGNTGFGNAGDVN-------------------------
Rv3159c|M.tuberculosis_H37Rv -------FFNSGNNNFGFGNAGDIN-------------------------
MUL_0964|M.ulcerans_Agy99 -------FFNSGDGNFGFAHAGSTN-------------------------
MMAR_1550|M.marinum_M -------IGNSGAIDTGFGNSGFID-------------------------
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -------TGGTGGQGG-LGGGGGTG-----------------------GQ
Mvan_1264|M.vanbaalenii_PYR-1 -------TGGTGGQGG-LGGVGGTG-----------------------GT
MSMEG_0868|M.smegmatis_MC2_155 SNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATDGH
MLBr_01182|M.leprae_Br4923 -------SSSGGHVTAQLGRAASIG-------------------------
MAB_4284c|M.abscessus_ATCC_199 -------NAAVAGNAAVAGNAAVAG-------------------------
TH_3569|M.thermoresistible__bu --------------LFAVAYQVFTN-------------------------
Mb3184c|M.bovis_AF2122/97 ------TGFWNGGPFN----------------TGFGNGGN-----TNFGF
Rv3159c|M.tuberculosis_H37Rv ------TGFGNAGDTN----------------TGFGNAGF-----FNMGI
MUL_0964|M.ulcerans_Agy99 ------TGFWNSGGTN----------------TGFGNGGS-----LNFGF
MMAR_1550|M.marinum_M ------TGIGNSGALN----------------TGIGNSGLNAGSGFNVGF
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGS
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGV
MSMEG_0868|M.smegmatis_MC2_155 GGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGGD
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----NAAVGGVLNTG---------------VSGAIGGSSHVGGAINESL
TH_3569|M.thermoresistible__bu --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 GNAGFQNMGHGNAGGVNVGSGNAGLANTGDFNSG---------GVVSGIG
Rv3159c|M.tuberculosis_H37Rv GNAGNEDMGVGNGGSFNVGVGNAGNQSVG-FGNA---------GTLN---
MUL_0964|M.ulcerans_Agy99 GNGGVENMGHGNAGSFNMGFGNGGGGNTG-FYNS---------GTYN---
MMAR_1550|M.marinum_M GNSGINNFGVGNSGSFNAGSFNSSTSNLGSFNSGNFVLGGFNVGSFNSGA
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGSAGKA
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGSAGTA
MSMEG_0868|M.smegmatis_MC2_155 GVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGSTL
MLBr_01182|M.leprae_Br4923 -SLRVPQTWTTASQPVTAATRALSPARVAVATES----------------
MAB_4284c|M.abscessus_ATCC_199 GGSGSVGGSTAVGGGAHTGVGGGVSTGVGVGSHVG--------GGISESL
TH_3569|M.thermoresistible__bu -LVGWPTWAMILASPVLIPLAITLG-------------------------
Mb3184c|M.bovis_AF2122/97 GNTGSFNSGNLNTGFGNAGDLNTGL-------FNSGDVNTGIGSTVDQPG
Rv3159c|M.tuberculosis_H37Rv --VGFANAGSINTGFANSGSINTGG-------FDSGDRNTGFGSSVDQSV
MUL_0964|M.ulcerans_Agy99 --TGFSNAAETNTGWENSGNVNTGG-------YNSGGLNTGIGSPDTQAG
MMAR_1550|M.marinum_M HNTGAFNAGGYNTGFWNAGDINTGM-------WNSGDLNTGLGSAITQTV
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAGKAGATG
Mvan_1264|M.vanbaalenii_PYR-1 GVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGASGAQGSAG
MSMEG_0868|M.smegmatis_MC2_155 GGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGDGG
MLBr_01182|M.leprae_Br4923 -----ESAPLLGGGLPMAPMVPGGG-------SGTGGVNTALRLQPRAFV
MAB_4284c|M.abscessus_ATCC_199 GGSGSVGGSTAVGGGAHTGVGGGVS----------TGVGVGSHVGGGISE
TH_3569|M.thermoresistible__bu -----VAGLVMIADQAQPPAEEAAP---------EEDVAAPVRAEPQNPL
Mb3184c|M.bovis_AF2122/97 SVSGFGNTGTSV----------------SGFNNSGNL--TSGFGNMNSNV
Rv3159c|M.tuberculosis_H37Rv SSSGFGNTGMNS----------------SGFFNTGNV--SAGYGNNG---
MUL_0964|M.ulcerans_Agy99 PNSGFGHSGSGN----------------SGFFNSGDG--NSGFENSNTCV
MMAR_1550|M.marinum_M ANSGFFNAGSTS----------------SGLFNVGSGGHNSGFVNVGSG-
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK AAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKA
Mvan_1264|M.vanbaalenii_PYR-1 SAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKA
MSMEG_0868|M.smegmatis_MC2_155 AATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADGWV
MLBr_01182|M.leprae_Br4923 MPRNPAAG------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 SLGGSGSVGGST--------------AVGGGAHTGVGGGVNTGVGVGSHV
TH_3569|M.thermoresistible__bu PLTXXX--------------------------------------------
Mb3184c|M.bovis_AF2122/97 -FDSTSGFQNIGDANVGFFNSGNSNEGFFNTGM-----------------
Rv3159c|M.tuberculosis_H37Rv --DVQSGINNT--------NSGGFNVGFYNSGA-----------------
MUL_0964|M.ulcerans_Agy99 SANGHSGVRNS---------GDATNVGFSNSGS-----------------
MMAR_1550|M.marinum_M --GYNSGFFNLG--------AGGSNAGFFNSGAGGGNTGLLNLGN-----
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG-------
Mvan_1264|M.vanbaalenii_PYR-1 GATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG-------
MSMEG_0868|M.smegmatis_MC2_155 QAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWKS
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GGGISESLGGSGSVGGSTAVGGGAHTSAINDALGGSGS------------
TH_3569|M.thermoresistible__bu --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 ---FNNGIYNSG--VASTGIANSGNA------------SSGVAN-SGDNS
Rv3159c|M.tuberculosis_H37Rv ---GTVGIANSG--LQTTGIANSGTL------------NTGVAN-TGDHS
MUL_0964|M.ulcerans_Agy99 ---NNTGIFNTG--TFNTGIANSGSD------------SSGLLI-SGTNS
MMAR_1550|M.marinum_M -GGNNTGFFNVGNGGYNTGFVNAGSDGSNAGFFTLGGYNSGVLN-IGSLN
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGGSG-AGGAG
Mvan_1264|M.vanbaalenii_PYR-1 ----AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGGSG-TGGAG
MSMEG_0868|M.smegmatis_MC2_155 GGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTT-AGGSG
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----VGGSTAVGGGAHTSAINESMNSSINASHSSSMNESFGSSMGSHGAA
TH_3569|M.thermoresistible__bu --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 SGAFNQGDNQAGFFGQP-----------
Rv3159c|M.tuberculosis_H37Rv SGGFNQGSDQSGFFGQP-----------
MUL_0964|M.ulcerans_Agy99 SGALNSGDDQSGFNN-------------
MMAR_1550|M.marinum_M SGVLNSGTANSGVPLILLLSLLSFVPLL
MAV_4704|M.avium_104 ----------------------------
Mflv_5091|M.gilvum_PYR-GCK --GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 --GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 NGGNGGNGGNGGADGTPGTAGTTGANNP
MLBr_01182|M.leprae_Br4923 ----------------------------
MAB_4284c|M.abscessus_ATCC_199 GTGFEAQGHAQGHASETAHTTLPGAEHH
TH_3569|M.thermoresistible__bu ----------------------------