For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MNYSVLPPEINSLRMFTGAGSAPMLAASVAWDGLAAELAVAASSFGSVTSGLAGQSWQGAAAAMAAAAAP YAGWLAAAAARAAGASAQAKAVASAFEAARAATVHPMLVAANRNAFVQLVLSNLFGQNAPAIAAAEAMYE QMWAADVAAMVGYHGGASAAAAALPSWQQALRGLPGLGQVASAISGGAASMFAAPAAATAAVTPPALNTG LGNIGSWNLGGGNVGLLNLGSGNFGSLNLGGGNTGNANLGGGNWGFANLGSGNIGNTNFGNGNQGNLNFG SGNLLGNGNFGFGNAFGDGNLGSGNVGSTNLGSGNFGSFNVGSGNMGMSNIGFGNLGNNNLGFGNNGNNN IGFGLTGDNLVGIGALNSGIGNMGFGNSGNNNIGFFNSGNGNVGFFNSGDGNTGFGNAGDVNTGFWNGGP FNTGFGNGGNTNFGFGNAGFQNMGHGNAGGVNVGSGNAGLANTGDFNSGGVVSGIGGNTGSFNSGNLNTG FGNAGDLNTGLFNSGDVNTGIGSTVDQPGSVSGFGNTGTSVSGFNNSGNLTSGFGNMNSNVFDSTSGFQN IGDANVGFFNSGNSNEGFFNTGMFNNGIYNSGVASTGIANSGNASSGVANSGDNSSGAFNQGDNQAGFFG QP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3184c | PPE70 | - | 100% (632) | PPE family protein |
| M. bovis AF2122 / 97 | Mb3183c | PPE53 | 0.0 | 71.04% (632) | PPE family protein |
| M. bovis AF2122 / 97 | Mb1166c | PPE16 | 0.0 | 62.77% (642) | PPE family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5091 | - | 3e-28 | 27.72% (624) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv3159c | PPE53 | 0.0 | 70.93% (633) | PPE family protein |
| M. leprae Br4923 | MLBr_01182 | - | 6e-30 | 36.45% (214) | PPE-family protein |
| M. abscessus ATCC 19977 | MAB_4284c | - | 1e-24 | 29.68% (438) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_1402 | - | 0.0 | 68.42% (646) | PPE family protein |
| M. avium 104 | MAV_4704 | - | 1e-50 | 55.26% (190) | PPE family protein |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 5e-26 | 28.14% (533) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3113 | - | 3e-24 | 40.99% (161) | PUTATIVE PPE protein |
| M. ulcerans Agy99 | MUL_0902 | - | 0.0 | 66.36% (642) | PPE family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 4e-30 | 26.47% (665) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3184c|M.bovis_AF2122/97 --------------------------------------------------
Rv3159c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0902|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1402|M.marinum_M --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 --------------------------------------------------
Rv3159c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0902|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1402|M.marinum_M --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 --------------------------------------------------
Rv3159c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0902|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1402|M.marinum_M --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 --------------------------------------------------
Rv3159c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0902|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1402|M.marinum_M --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 ------------------------------------------MN---YSV
Rv3159c|M.tuberculosis_H37Rv ------------------------------------------MN---YSV
MUL_0902|M.ulcerans_Agy99 ------------------------------------------MN---FPM
MMAR_1402|M.marinum_M ------------------------------------------MS---FAV
MAV_4704|M.avium_104 ------------------------------------------MTNPHFAW
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
MLBr_01182|M.leprae_Br4923 --------------------------------------------MFDFAA
TH_3113|M.thermoresistible__bu ------------------------------------------------MA
MAB_4284c|M.abscessus_ATCC_199 ----------------------------------------MSIIDFILNL
Mb3184c|M.bovis_AF2122/97 LPPEINSLRMFTGAGSAPMLAASVAWDG--------LAAELAVAASSFGS
Rv3159c|M.tuberculosis_H37Rv LPPEINSLRMFTGAGSAPMLAASVAWDR--------LAAELAVAASSFGS
MUL_0902|M.ulcerans_Agy99 LPPEINSARMFAGAGSGPMLSAAMAWDG--------LAVELGSAAESFGS
MMAR_1402|M.marinum_M LPPEINSLRIFAGAGSAPMLEAAVAWDG--------LSAELGTAAESFAS
MAV_4704|M.avium_104 LPPEVNSALIYSGPGPGPLLAAAAAWDG--------LAEELASSAQSFSS
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
MLBr_01182|M.leprae_Br4923 LSPETNSTRMYLGPGSSPILTAAAAWVV--------LAKELTAAAQGLQS
TH_3113|M.thermoresistible__bu LPPEVHSTLLRTGPGPGALSAAADAWRM--------LSDEYRAAAVELAA
MAB_4284c|M.abscessus_ATCC_199 FRDPVEAASYVADPEAALANAGLSAVSAAQVGAVMPVVAESVASNYGYQS
. . . : . .
Mb3184c|M.bovis_AF2122/97 VTSG---------LAGQSWQG-AAAAMAAAAAPYAGWLAAAAARAAGASA
Rv3159c|M.tuberculosis_H37Rv VTSG---------LAGQSWQGAAAAAMAAAAAPYAGWLAAAAARAAGASA
MUL_0902|M.ulcerans_Agy99 VTSG---------LVGSSWQGAAATAMSAAAAPYVSWLNAAAVRAGEAAL
MMAR_1402|M.marinum_M VTSG---------LTGQAWQGAAAKAMAAVAAPYSSWLSAAAARAAGAAG
MAV_4704|M.avium_104 VTSD---------LASGSWQGASSAAMMTVANQYVSWLSAAAAQAEEVSH
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
MLBr_01182|M.leprae_Br4923 AVEA----------LLTTFEGESAAALAERVTPYEKWLTQNAASAELTAT
TH_3113|M.thermoresistible__bu VVSQT---------CATAWEGVGADAYAAAHGPYLFWLTDTAAAAAAAGA
MAB_4284c|M.abscessus_ATCC_199 QWVNTGN-----PIHDLSGNLQNYYAAQPDGPSILSPSLLSPRDNDFLSH
.
Mb3184c|M.bovis_AF2122/97 QAKAVASAFEAARAATVHPMLVAANRNAFVQLVLSN-------------L
Rv3159c|M.tuberculosis_H37Rv QAKAVASAFEAARAATVHPMLVAANRNAFVQLVLSN-------------L
MUL_0902|M.ulcerans_Agy99 QAKEVVSAFEAARAAMIHPLAVAANRNALVQLVLTN-------------L
MMAR_1402|M.marinum_M QAKMVASAFEAARSAMVHPLAVAANRNVFVQLVMSN-------------L
MAV_4704|M.avium_104 QASAIATAFEVALAATVQPAVVAANRALVQALAATN-------------W
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
MLBr_01182|M.leprae_Br4923 QLTVAANAYETAFTMTVPPLMVFVNRAQACLLIMSN-------------I
TH_3113|M.thermoresistible__bu QLEAAAAAHASALAAMPTMAELTANRTTHAALVATN-------------F
MAB_4284c|M.abscessus_ATCC_199 NDTDFASHNPIASGNQVMSPSGNVDSFNRGPLLDLSFG--------DLQF
.
Mb3184c|M.bovis_AF2122/97 FGQNAPAIAAAEAMYEQMWAADVAAMVGYHGGAS----------------
Rv3159c|M.tuberculosis_H37Rv FGQNAPAIAAAEAMYEQMWAADVAAMVGYHGGAS----------------
MUL_0902|M.ulcerans_Agy99 FGQNAPAIAAAEGSYEQMWAADVAAMLGYHGGAS----------------
MMAR_1402|M.marinum_M FGQNAPAIAATEGTYEEMWAADVAAMVGYHGGAS----------------
MAV_4704|M.avium_104 LGQNTPAIADIEAAYEQMWASDVAAMFGYHADAS----------------
Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----AVGAAG------
Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----AIGTAG------
MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH
MLBr_01182|M.leprae_Br4923 FGQNSTAIAEKEAEYTEMWIQDAAAMTSYQASVL----------------
TH_3113|M.thermoresistible__bu FGVNTIPIAVNEADYARMWIQAATTMATYEAVAS----------------
MAB_4284c|M.abscessus_ATCC_199 GNRDTTAIGDGAVAVGGSNSGPIASGQGSTAVNG---------------D
. . .
Mb3184c|M.bovis_AF2122/97 ----AAAAALPSWQQALRGLPGLGQVASAISGGAASMFAAPAAATAAVTP
Rv3159c|M.tuberculosis_H37Rv ----AAAAQLSSWSIGLQ----------------QALPAAPSALAAAIG-
MUL_0902|M.ulcerans_Agy99 ----AAASGLASWQQALQG---------------LAGPAASVILGLSIGN
MMAR_1402|M.marinum_M ----AAASGLPSWQQALSG--------------LPGIGQAAAAPAAALFN
MAV_4704|M.avium_104 ----AAVAKLPPWNEVLQ--------------------------------
Mflv_5091|M.gilvum_PYR-GCK -AAGTVGTAGATGGTGTGANGGAGGVG-----GVGGTGAAGAAGGAGGLG
Mvan_1264|M.vanbaalenii_PYR-1 -VAGAAGTAGATGGTGVGGNGGAGQAG-----GIGGTGAAGAAGQAGTAG
MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS
MLBr_01182|M.leprae_Br4923 ----EAVGATKAFTAPPLG-------------------------------
TH_3113|M.thermoresistible__bu ----AAVSATPRTVAPPP--------------------------------
MAB_4284c|M.abscessus_ATCC_199 VRDSNIINADHGSNVGVDQSQTRVGGDYTNVSGHGSADIDKSVTVVDDHS
Mb3184c|M.bovis_AF2122/97 PAL-NTGLGNIG--------------------------------------
Rv3159c|M.tuberculosis_H37Rv -------LGNIG--------------------------------------
MUL_0902|M.ulcerans_Agy99 TGVGNLSIGNIG--------------------------------------
MMAR_1402|M.marinum_M LPTVNTGLGNSG--------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ETGTTGGAGGVG--------------------GQGTAGGTGGVGGIGGAG
Mvan_1264|M.vanbaalenii_PYR-1 ETGVTGGVGGIG--------------------GQGTEGGTGGVGGVGGVG
MSMEG_0868|M.smegmatis_MC2_155 TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIY
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 QRNTTNINDSFN--------------------------------------
Mb3184c|M.bovis_AF2122/97 -------------------------------------------------S
Rv3159c|M.tuberculosis_H37Rv -------------------------------------------------V
MUL_0902|M.ulcerans_Agy99 -------------------------------------------------V
MMAR_1402|M.marinum_M -------------------------------------------------Q
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------STGAVGG-------VGGKG----IQGGQG-----------
Mvan_1264|M.vanbaalenii_PYR-1 ----------ATGGAGG-------VGGKG----IQGGQG-----------
MSMEG_0868|M.smegmatis_MC2_155 SGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTA
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 WNLGGGNVGLLNLGSGNFGSLNLGG-------------------------
Rv3159c|M.tuberculosis_H37Rv GNLGGGNTGDYNLGSGNSGNANVGS-------------------------
MUL_0902|M.ulcerans_Agy99 FNLGGGNAGNLNLGGGNTGNANLGS-------------------------
MMAR_1402|M.marinum_M WNLGGGNNGSFNLGSGNFGNLNLGG-------------------------
MAV_4704|M.avium_104 -----------NLGFSNASTAVTRP-------------------------
Mflv_5091|M.gilvum_PYR-GCK --LQGGKGGDGGAGGKGGDADSMGS------------------AGATGGK
Mvan_1264|M.vanbaalenii_PYR-1 --LQGGQGGDGGTGGTGGDATSMGE------------------AGATGGK
MSMEG_0868|M.smegmatis_MC2_155 KAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAV
MLBr_01182|M.leprae_Br4923 -------VNEVGLAQEVVEEVVEEV-------------------------
TH_3113|M.thermoresistible__bu ---------ILGAGTGESATAAITG-------------------------
MAB_4284c|M.abscessus_ATCC_199 ------TDRSTNIGSGNTTNTEIGSHN-----------------------
. .
Mb3184c|M.bovis_AF2122/97 --------------------------------------------------
Rv3159c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0902|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1402|M.marinum_M --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GGNGGNGGRGGLFG---------------KGGNAGNGAD-----------
Mvan_1264|M.vanbaalenii_PYR-1 GGNGGNGGRGSLFG---------------RGGNAGNGGN-----------
MSMEG_0868|M.smegmatis_MC2_155 GGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGP
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 --------------------GNTGNANLGGGNWGF---------------
Rv3159c|M.tuberculosis_H37Rv --------------------GNSGNANVGSGNDGA---------------
MUL_0902|M.ulcerans_Agy99 --------------------GNNGFFNLGSGNTGN---------------
MMAR_1402|M.marinum_M --------------------GNIGNLNLGGGNFGF---------------
MAV_4704|M.avium_104 --------------------AGSGAVARG---------------------
Mflv_5091|M.gilvum_PYR-GCK -----------GGTGGAGGAGGTGG-TGGAGGTGG---------------
Mvan_1264|M.vanbaalenii_PYR-1 -----------GGTGGNGGNGGTGG-TGGNGGTGG---------------
MSMEG_0868|M.smegmatis_MC2_155 AGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQ
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -------------------QANIGTSTSAGGSAAVG--------------
Mb3184c|M.bovis_AF2122/97 ----ANLGSGNIGNTNFGNGNQGNLNFGSGNLLGNGNFGFGNAFGDGNLG
Rv3159c|M.tuberculosis_H37Rv ----TNLGSGNIGNTNLGSGNVGNVNLGSGNR-GFGNLGNGN-FGSGNLG
MUL_0902|M.ulcerans_Agy99 ----TNFGNGNRGNLNWGSGNLGNANVGFGNFLGQGNFGFGNRVGDANLG
MMAR_1402|M.marinum_M ----ANLGNGNIGNTNFGSGNNGNLNFGGGNL-GSGNFGLGN-FGSGNFG
MAV_4704|M.avium_104 ----------------YTSRIAGFLAPRAPQ-------------------
Mflv_5091|M.gilvum_PYR-GCK --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKG
Mvan_1264|M.vanbaalenii_PYR-1 --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKG
MSMEG_0868|M.smegmatis_MC2_155 TDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGRG
MLBr_01182|M.leprae_Br4923 ----------------VEEVVEAEQAISQAALDQAVNEGMEATVVPQVDQ
TH_3113|M.thermoresistible__bu -------------AHVTAELRAAESRTLLDEINELIDRLFAPLFPPGFAD
MAB_4284c|M.abscessus_ATCC_199 ----GNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAG
.
Mb3184c|M.bovis_AF2122/97 SGN-------VGSTNLGSGNFGSFN-----------------VGSGNMGM
Rv3159c|M.tuberculosis_H37Rv SGN-------TGSTNFGGGNLGSFN-----------------LGSGNIGS
MUL_0902|M.ulcerans_Agy99 SGN-------LGNANFGNGNLGDTN-----------------LGSGNNGF
MMAR_1402|M.marinum_M NANGMDPVSFSTGNNIGDANLGAFN-----------------LGSANIGL
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGGTGGTGG
MSMEG_0868|M.smegmatis_MC2_155 GDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNGG
MLBr_01182|M.leprae_Br4923 QVN-----------------------------------------------
TH_3113|M.thermoresistible__bu ALP-----------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 LAGNAGLAGNAG--LAGNAGLAGNAGLAGN-----------AGLAGNAGL
Mb3184c|M.bovis_AF2122/97 SN--------------IGFGNLGNNNLGFGNNGNNNIGFG----------
Rv3159c|M.tuberculosis_H37Rv SN--------------IGFGNNGDNNLGLGNNGNNNIGFG----------
MUL_0902|M.ulcerans_Agy99 SN--------------VGFGNLGSNNLGFGNNGDNNIGFG----------
MMAR_1402|M.marinum_M SN--------------IGLANIGNNNFGFGNVGNNNIGFG----------
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK AG-----------DGTGGTGGTGG----TGGQGGQGGQGG----------
Mvan_1264|M.vanbaalenii_PYR-1 AG-----------DGLGGTGGTGG----TGGFGGQGGQGG----------
MSMEG_0868|M.smegmatis_MC2_155 AGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVIG
MLBr_01182|M.leprae_Br4923 ----------------VDVATPQTAVPDSSSAAAPQLWGG----------
TH_3113|M.thermoresistible__bu ----------------DGLLGTLLAPLLPGATGDGPPMAT----------
MAB_4284c|M.abscessus_ATCC_199 AG-------------NAGLAGNAGLAGNAGLAGNAGLAGN----------
Mb3184c|M.bovis_AF2122/97 ------LTGDNLVGIG--ALNSGIG---------------------NMGF
Rv3159c|M.tuberculosis_H37Rv ------LTGDNLVGIG--ALNSGIG---------------------NLGF
MUL_0902|M.ulcerans_Agy99 ------LTGNNQVGINFAGLNGGIG---------------------NIDL
MMAR_1402|M.marinum_M ------LTGDNQVGIG--SLNAGTG---------------------NFGF
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -------TGGTGGQGG-LGGGGGTG-----------------------GQ
Mvan_1264|M.vanbaalenii_PYR-1 -------TGGTGGQGG-LGGVGGTG-----------------------GT
MSMEG_0868|M.smegmatis_MC2_155 SNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATDGH
MLBr_01182|M.leprae_Br4923 -------FAQHLSPIN--------------------------------DT
TH_3113|M.thermoresistible__bu ------IMSFLLMGLS------------------------------NPAY
MAB_4284c|M.abscessus_ATCC_199 -----AGLAGNAGLAGNAGLAGNAAVAG------------------NAAV
Mb3184c|M.bovis_AF2122/97 GNSGNNNIGFFNSGNGNVGFFNSGDGNTGFGNAGDVNTGFWNGGPFNTGF
Rv3159c|M.tuberculosis_H37Rv GNSGNNNIGFFNSGNNNVGFFNSGNNNFGFGNAGDINTGFGNAGDTNTGF
MUL_0902|M.ulcerans_Agy99 GNSGDNNVGFFNSGSNNVGFFNSGDRNFGFANSGDTNTGFWNAGRVNTGF
MMAR_1402|M.marinum_M GNSGDNNIGFFNSGSGNVGVFNSGDGNTGFGNSGGVNSGFWNSGGLNTGF
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGS
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGV
MSMEG_0868|M.smegmatis_MC2_155 GGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGGD
MLBr_01182|M.leprae_Br4923 LSMINNHAGMANAGLSLVNGMGSAMKSLAPTTTKAAESAFKAMGSAVQST
TH_3113|M.thermoresistible__bu LFPVLVYLLFTGVVHTTVAVSGMLAQLVPLMPALLPVAVAALGGLAGVWA
MAB_4284c|M.abscessus_ATCC_199 AGNAAVAGNAAVGGVLNTGVSGAIGGSSHVGGAINESLGGSGSVGGSTAV
Mb3184c|M.bovis_AF2122/97 GNGGNTNFGFGNAGFQNMGHGNAGGVNVGSGNAGLANTGDFNSGGVVSGI
Rv3159c|M.tuberculosis_H37Rv GNAGFFNMGIGNAGNEDMGVGNGGSFNVGVGNAGNQSVG-FGNAGTLN--
MUL_0902|M.ulcerans_Agy99 GNGGNFNLGFGNGGAANVGVGNGGGGNLGFGNSGTENTGSFNSGGDNGRN
MMAR_1402|M.marinum_M GNAGANNLGFSNAGSSNVGDSNAGGSNMGSGNAGYSNTGFFNSGGSATFI
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGSAGKA
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGSAGTA
MSMEG_0868|M.smegmatis_MC2_155 GVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGSTL
MLBr_01182|M.leprae_Br4923 GRGLLGSSSGGHVTAQLGRAASIGSLRVPQTWTTASQPVTAATRALSPAR
TH_3113|M.thermoresistible__bu GLSGLAGLAGLTAVPAADGGASAAPVPAGGPSLPSGSSAPPAPTGSAAPT
MAB_4284c|M.abscessus_ATCC_199 GGGAHTGVGGGVSTGVGVGSHVGGGISESLGGSGSVGGSTAVGGGAHTGV
Mb3184c|M.bovis_AF2122/97 GGNTGSFNSGNLNTGFGNAGDLNTG----LFNSGDVNTGIGSTVDQP-GS
Rv3159c|M.tuberculosis_H37Rv ---VGFANAGSINTGFANSGSINTG----GFDSGDRNTGFGSSVDQS-VS
MUL_0902|M.ulcerans_Agy99 GGNTGSFNSGYVNTGFFNSGSTNTG----LFNAGSVNTGIGSPDTQP-GS
MMAR_1402|M.marinum_M GGNTGFFNSGDLNTGGGNAGSVNTG----FLNSGDFNTTVGSADTPAGAT
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAGKAGATG
Mvan_1264|M.vanbaalenii_PYR-1 GVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGASGAQGSAG
MSMEG_0868|M.smegmatis_MC2_155 GGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGDGG
MLBr_01182|M.leprae_Br4923 VAVATESESAPLLGGGLPMAPMVPGG-----GSGTGGVNTALRLQPRAFV
TH_3113|M.thermoresistible__bu TGTAPGGAGSPPPAGHSVPPAPHSAP-----PVGTSGPPYLIAAQPAPGV
MAB_4284c|M.abscessus_ATCC_199 GGGVSTGVGVGSHVGGGISESLGGSG-----SVGGSTAVGGGAHTGVGGG
Mb3184c|M.bovis_AF2122/97 VSGFGNTG-------------------TSVSGFNNS-----GNLTSGFGN
Rv3159c|M.tuberculosis_H37Rv SSGFGNTG-------------------MNSSGFFNT-----GNVSAGYGN
MUL_0902|M.ulcerans_Agy99 ISGFGNTG-------------------AGVSGFNNS-----GDATSGFMN
MMAR_1402|M.marinum_M QSGFWNTG-------------------DNVSGFNNTNDAMFGGGVSGFQN
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK AAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKA
Mvan_1264|M.vanbaalenii_PYR-1 SAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKA
MSMEG_0868|M.smegmatis_MC2_155 AATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADGWV
MLBr_01182|M.leprae_Br4923 MPRNPAAG------------------------------------------
TH_3113|M.thermoresistible__bu ARRSAGAR------------------------RAASIVEPAGSAAAAAAA
MAB_4284c|M.abscessus_ATCC_199 VNTGVGVGSHVG---------------GGISESLGGSGSVGGSTAVGGGA
Mb3184c|M.bovis_AF2122/97 MNSNVFDSTSGFQNIGDANVGFFNS-GNSNEGFFNTGMFNNGIYNS----
Rv3159c|M.tuberculosis_H37Rv NG----DVQSGINNT--------NS-GGFNVGFYNSGAGTVGIANS----
MUL_0902|M.ulcerans_Agy99 VATT-FGFASGINNV-----------GDYQVGLFNTGFGNAGIANS----
MMAR_1402|M.marinum_M MNTGFFSVGSGFGNTGEYQVGFNNAGTGFNTGVGNTGSFNTGFNVT----
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG-------
Mvan_1264|M.vanbaalenii_PYR-1 GATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG-------
MSMEG_0868|M.smegmatis_MC2_155 QAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWKS
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu RESAPIRRRRGQKDGLHGHRHEHQQPASMSAATAPSAAG-----------
MAB_4284c|M.abscessus_ATCC_199 HTSAINDALGGSGSVGGSTAVGGGAHTSAINESMNSSINASHSSSMN---
Mb3184c|M.bovis_AF2122/97 -------------------------------GVASTGIANSGNASSGVAN
Rv3159c|M.tuberculosis_H37Rv -------------------------------GLQTTGIANSGTLNTGVAN
MUL_0902|M.ulcerans_Agy99 -------------------------------GNATFGIANSGALSSGISN
MMAR_1402|M.marinum_M -------------------------------GSGSSGFGHSGDGSSGLAN
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGGSGAGGAG-
Mvan_1264|M.vanbaalenii_PYR-1 ----AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGGSGTGGAG-
MSMEG_0868|M.smegmatis_MC2_155 GGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGN
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------IRVLGGAGRISRTRGSVP
MAB_4284c|M.abscessus_ATCC_199 ---------------------------------ESFGSSMGSHGAAGTGF
Mb3184c|M.bovis_AF2122/97 SGDNSSGAFNQGDNQAGFFGQP-----
Rv3159c|M.tuberculosis_H37Rv TGDHSSGGFNQGSDQSGFFGQP-----
MUL_0902|M.ulcerans_Agy99 SGTNSSGGFNTGDDQSGFFN-------
MMAR_1402|M.marinum_M SGDSSSGAFNETDNTAGFFGQS-----
MAV_4704|M.avium_104 ---------------------------
Mflv_5091|M.gilvum_PYR-GCK -GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 -GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 GGNGGNGGNGGADGTPGTAGTTGANNP
MLBr_01182|M.leprae_Br4923 ---------------------------
TH_3113|M.thermoresistible__bu HAEITPGDPTEPSSPTDRAHRPAEPN-
MAB_4284c|M.abscessus_ATCC_199 EAQGHAQGHASETAHTTLPGAEHH---