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aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_3569 | - | - | 100% (343) | PPE protein |
M. thermoresistible (build 8) | TH_3113 | - | 9e-65 | 43.63% (353) | PUTATIVE PPE protein |
M. thermoresistible (build 8) | TH_4447 | - | 1e-38 | 43.69% (206) | PUTATIVE PPE protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0294 | PPE4 | 6e-95 | 55.02% (329) | PPE family protein |
M. gilvum PYR-GCK | Mflv_0325 | - | 1e-110 | 60.95% (338) | PPE protein |
M. tuberculosis H37Rv | Rv0286 | PPE4 | 6e-95 | 55.02% (329) | PPE family protein |
M. leprae Br4923 | MLBr_01991 | PPE | 4e-60 | 44.67% (300) | PPE-family protein |
M. abscessus ATCC 19977 | MAB_2230c | - | 1e-92 | 53.15% (333) | PPE family protein |
M. marinum M | MMAR_0545 | - | 1e-95 | 55.76% (330) | PPE family protein, PPE4 |
M. avium 104 | MAV_4867 | - | 8e-86 | 53.02% (315) | PPE family protein |
M. smegmatis MC2 155 | MSMEG_0619 | - | 1e-132 | 70.41% (338) | PPE family protein |
M. ulcerans Agy99 | MUL_1208 | - | 2e-95 | 55.45% (330) | PPE family protein |
M. vanbaalenii PYR-1 | Mvan_0415 | - | 1e-115 | 62.57% (342) | PPE protein |
CLUSTAL 2.0.9 multiple sequence alignment TH_3569|M.thermoresistible__bu ---------MMTAPIWMALPPEVHSALLSSGPGPGSLLAAASAWHALSAE MSMEG_0619|M.smegmatis_MC2_155 ----------MTAPIWMALPPEVHSSLLSSGPGPGSLLAAAGAWQSLSAE Mflv_0325|M.gilvum_PYR-GCK MTSPVASLAPVTSPVWMALPPEVHSTMLSSGPGPGSLLAAGVAWQSLSAE Mvan_0415|M.vanbaalenii_PYR-1 ----------MSSPVWMALPPEVHSALLSSGPGPGSMLAAAATWQSLSAE Mb0294|M.bovis_AF2122/97 ----------MAAPIWMASPPEVHSALLSNGPGPGSLVAAATAWSQLSAE Rv0286|M.tuberculosis_H37Rv ----------MAAPIWMASPPEVHSALLSNGPGPGSLVAAATAWSQLSAE MMAR_0545|M.marinum_M -------MAVAAGPIWIASPPEVHSAMLSSGPGPASLLAAAGVWSALSAE MUL_1208|M.ulcerans_Agy99 -------MAVAAGPIWIASPPEVHSAMLSSGPGPASLLAAAGVWSALSAE MAV_4867|M.avium_104 -------MTSPFGPIWMASPPEVHSALLSAGPGPGPLLAAAGAWTSLSAQ MAB_2230c|M.abscessus_ATCC_199 ----------MSAPIWMASPPEVHSALLSAGPGPGALLAAAAQWQALSVQ MLBr_01991|M.leprae_Br4923 ----------------MAIPPEVHSVLLSAGQGAESLLVAATQWQELSKQ :* ****** :** * *. .::.*. * ** : TH_3569|M.thermoresistible__bu YASAAAELSSVLANVQAGSWEGPSAERYVAAHAPYLAWLTQQSANSAATA MSMEG_0619|M.smegmatis_MC2_155 YAAAAAELTSVLSAVQAGSWEGPSSEQYVAAHAPYLQWLAQQSANSAAAA Mflv_0325|M.gilvum_PYR-GCK YASAAAELTSILAGVQSGAWEGPSSQQYVAAHTPYLAWLAQQSAVSAATA Mvan_0415|M.vanbaalenii_PYR-1 YAAAAAELSSILADVQAGAWEGPSSEQYVAAHTPYLAWLAQQSAAGAAAA Mb0294|M.bovis_AF2122/97 YASTAAELSGLLGAVPGWAWQGPSAEWYVAAHLPYVAWLTQASADAAGAA Rv0286|M.tuberculosis_H37Rv YASTAAELSGLLGAVPGWAWQGPSAEWYVAAHLPYVAWLTQASADAAGAA MMAR_0545|M.marinum_M YALTAAELSEVLAAVQAGAWQGPSGFQYVAAHLPYVAWLLQASADGAGKA MUL_1208|M.ulcerans_Agy99 YALTAAELSEVLAAVQAGAWQGPSGFQYVAAHLPYVAWLLQASADGAGKA MAV_4867|M.avium_104 YATAAAELSALLGEAQAGSWEGESAAQYAAAHLPYLAWLQQASADSAGAA MAB_2230c|M.abscessus_ATCC_199 YTTAATELTQLLAATGSGSWQGPSAAQYVASHAPYLAWLTQQSAMSATNA MLBr_01991|M.leprae_Br4923 YTYAAAELTRLLTHVQATSWRGTSATRFVAAHGAYLVWLEQTSINNAITA *: :*:**: :* . . :*.* *. :.*:* .*: ** * * * * TH_3569|M.thermoresistible__bu GRHETAAAAYSTALATMPTMAELTLNKTTHAVLVATNFLGINTIPIALNE MSMEG_0619|M.smegmatis_MC2_155 VQHETAAAAYSTALATMPTMAELALNHTMHGVLVATNFFGINTIPIALNE Mflv_0325|M.gilvum_PYR-GCK VQHDTAAAAYTTALATMPTLPELALNHTTHAVLVGTNFLGINTIPIALNE Mvan_0415|M.vanbaalenii_PYR-1 AQHEAAAAAYSTALATMPTLPELALNHTTHAVLVATNFLGINTIPIAMTE Mb0294|M.bovis_AF2122/97 AQHEAAAAAYTTALAAMPTLAELAANHVIHTVLVATNFFGINTIPITLNE Rv0286|M.tuberculosis_H37Rv AQHEAAAAAYTTALAAMPTLAELAANHVIHTVLVATNFFGINTIPITLNE MMAR_0545|M.marinum_M AEHEAAAVAYSGALAAMPTLTELGANHALHGVLVATNFFGLNAIPIALNE MUL_1208|M.ulcerans_Agy99 AEHEAAAVAYSGALAAMPTLTELGANHALHGVLVATNFFGLNAIPIALNE MAV_4867|M.avium_104 AQQEVAATAYTTALAAMPTLAELAANHTIHGVLLATNFFGINTIPIAVNE MAB_2230c|M.abscessus_ATCC_199 VLHETSAAAYTTALAAMPTLAELAANHMIHGVLLATNFFGINTIPIALNE MLBr_01991|M.leprae_Br4923 KQHEIAAIAYSSALAAMPTLAELTANRATRGFLIATNFFGINTIPIALNE :: :* **: ***:***:.** *: : .*:.***:*:*:***::.* TH_3569|M.thermoresistible__bu ADYVRMWIQAATSMSTYQAVAGTAVMSAPASSPAPLLLAPGVS-EAADAM MSMEG_0619|M.smegmatis_MC2_155 ADYVRMWIQAATTMSTYQAVSGAAVAAAPVSAPAPFLLKPGVG-EAGSAS Mflv_0325|M.gilvum_PYR-GCK ADYVRMWIQAATTMATYQSVSGAALAATPTSAPAPSVLLPGVG-EAGRAA Mvan_0415|M.vanbaalenii_PYR-1 ADYVRMWIQAATTMATYQAVSGAALAATPTATPAPFVLAPGVG-EAGRAA Mb0294|M.bovis_AF2122/97 ADYVRMWLQAAAVMGLYQAASGAALASAPRTVPAPTVMNPGGG------- Rv0286|M.tuberculosis_H37Rv ADYVRMWLQAAAVMGLYQAASGAALASAPRTVPAPTVMNPGGG------- MMAR_0545|M.marinum_M ADYVRMWVQAATTMGLYQATAGAALASAPRTGPPPKVVNPGGGQVAHLAA MUL_1208|M.ulcerans_Agy99 ADYVRMWVQAATTMGLYQATAGAALASAPRTGPPPKVVNPGGGQVAHLAA MAV_4867|M.avium_104 ADYARMWVQAATTMGTYQAVAGSALAAAPRTAPAPSIVKPGGE------- MAB_2230c|M.abscessus_ATCC_199 ADYIRMWIQAATTMGVYQGVSTAAVTSVAPTPPAPTIMAPGGE--MSRMS MLBr_01991|M.leprae_Br4923 ADYVRMWVQAADTMATYQAISEAVTATILPTQVAPPILAPGSA------- *** ***:*** *. **. : :. : : .* :: ** TH_3569|M.thermoresistible__bu ATTQQIGSQATAADSGTAL-NLSDLIANLLQYYQDYLDQLFGPIVDFLRD MSMEG_0619|M.smegmatis_MC2_155 ASVQQMSAQATAAESGSSL-DLSSIISDLLNQYLQGVPGGQ-AILDFLKD Mflv_0325|M.gilvum_PYR-GCK ADMSAFAAQPMAAQAGAAF-DVSNIIADIIRLYGEVLRFLFEPIFNFLRD Mvan_0415|M.vanbaalenii_PYR-1 ADVTAFAAQAQAAEAGSAL-DLSNIIADLIRAYGELLRFLFEPIFDFLRD Mb0294|M.bovis_AF2122/97 -------AASTVGAVNPWQ-WLLALLQQLWNAYTGFYGWMLQLIWQFLQD Rv0286|M.tuberculosis_H37Rv -------AASTVGAVNPWQ-WLLALLQQLWNAYTGFYGWMLQLIWQFLQD MMAR_0545|M.marinum_M DAAQAQSGAAAAGGSDPWQ-LLWQLLQYLWNAYTGFNTWMFDLIWEFLQD MUL_1208|M.ulcerans_Agy99 DAARAQSGAAAAGGSDPWQ-LLWQLLQYLWNAYTGFNTWMFDLIWEFLQD MAV_4867|M.avium_104 ----ANNLAANAAQNSSGD-WWQNFIQQLS---------------QFFQN MAB_2230c|M.abscessus_ATCC_199 ADMSGMAAQAQAAESGMALDDSESFFDKLMR-----------QIQEFFSD MLBr_01991|M.leprae_Br4923 --------TQNVLQS------VPDWIVQLLT-----------DILDFIAD . : : :*: : TH_3569|M.thermoresistible__bu PIGNLFQLIDDFLTNPAGALVTWWPLLFAVAYQVFTNLVGWPTWAMILAS MSMEG_0619|M.smegmatis_MC2_155 PLGNLGRLLTDFMTNPAGALATWWPFLFGVAYQVFFNLVGWPTWGMIFAS Mflv_0325|M.gilvum_PYR-GCK PIGNTFALITDFLTNPVQALITWGPFLLAVVYQAVSWVGASILYPSLFLL Mvan_0415|M.vanbaalenii_PYR-1 PLGNTIKLITDFLTNPAQALITWGPFLAAVAYQAVSWVGASILYPSLLLL Mb0294|M.bovis_AF2122/97 PIGNSIKIIIAFLTNPIQALITYGPLLFALGYQIFFNLVGWPTWGMILSS Rv0286|M.tuberculosis_H37Rv PIGNSIKIIIAFLTNPIQALITYGPLLFALGYQIFFNLVGWPTWGMILSS MMAR_0545|M.marinum_M PIGNTIKIIIAFLTNPLQAIITYGPLLFALSYQIFFNLVGWPTWALILSS MUL_1208|M.ulcerans_Agy99 PIGNTIKIIIAFLTNPLQAIITYGPLLFALSYQIFFNLVGWPTWALILSS MAV_4867|M.avium_104 ----IQKMLQDFWANLPAFLAANGPLLFFVAYQVFFNAVGWPTWGAILTA MAB_2230c|M.abscessus_ATCC_199 PLGTLQKILQDFMRNPLEALVAWGPLLFFIAYEAFFIPFGFTFWGVMLSA MLBr_01991|M.leprae_Br4923 PYKYFLRFFQRLGFRPAIAVVLA---IIALQLYDFLWYPYYASYG-MLLL :: : . : : : . : :: TH_3569|M.thermoresistible__bu PVLIPLAITLGVAGLVMIADQAQP-----PAEEAAPEEDVAAP------- MSMEG_0619|M.smegmatis_MC2_155 PFLIPALAALGITGLVLLIDHVLNNPVDVPAEDEAPQEVAAAPRTDQPLA Mflv_0325|M.gilvum_PYR-GCK PLLATTLAIVAGVGQHLLSLLNTP-PAEEAAEEPAPAQSAPSRPDQQSFP Mvan_0415|M.vanbaalenii_PYR-1 PLVATTLAIVLGVGAYLLENLPAP-AEDAPAEEPAASSPAPTRADQPSPA Mb0294|M.bovis_AF2122/97 PFLLPAGLGLGLAAIAFLPIVLAP--AVIPPASTPLAAAAVAAGSVWPAV Rv0286|M.tuberculosis_H37Rv PFLLPAGLGLGLAAIAFLPIVLAP--AVIPPASTPLAAAAVAAGSVWPAV MMAR_0545|M.marinum_M PFLLPAALGLALSAIAFTPIQIA---AEVPAAAAPLAAAAVTAKSVFPAA MUL_1208|M.ulcerans_Agy99 PFLLPAALGLALSAIAFTPIQIA---AEVPAAAAPLAAAAVTAKSVFPAA MAV_4867|M.avium_104 PFLLPLLLGIGLSSLLAAPAEIAP--VAAPAAITPVLASNKPP-TLPAAV MAB_2230c|M.abscessus_ATCC_199 PLWLPLLL-VGLAQLVNPVPVEAD----APADEPAPQQARVERSSPQQQP MLBr_01991|M.leprae_Br4923 PFFAPALSVLGTLSVLWNGQLSAG-----LPPNPAGSHPDNNAGPRIHVG *. . : . . TH_3569|M.thermoresistible__bu ------------VRAEPQNPLPLTXXX----------------------- MSMEG_0619|M.smegmatis_MC2_155 VGISPAGVPGSAATAAAPAPAPAGTTVAAPAPAAAT--FVPYAVANRDPG Mflv_0325|M.gilvum_PYR-GCK ATMSAPPPPSGAPIAANTVSAGSPPAPGAPAAAAAT--FVPYVVAGRDPY Mvan_0415|M.vanbaalenii_PYR-1 IAVSAPPPPSSAAATVGTVATGTAPAPGAPAAATAS--FVPYAVAGRDPG Mb0294|M.bovis_AF2122/97 SMAVTGAGTAGAATPAAGAAPSAGAAPAPAAPATAS--FAYAVGGSGDWG Rv0286|M.tuberculosis_H37Rv SMAVTGAGTAGAATPAAGAAPSAGAAPAPAAPATAS--FAYAVGGSGDWG MMAR_0545|M.marinum_M SLASPGTGSAGAPASGAGAGAPGSAPPGPAAPAPAS--FLYAVGGSGDWG MUL_1208|M.ulcerans_Agy99 SLASPGTGSAGAPASGAGAGAPGTAPPGPGAPAPAS--FLYAVGGSGDWG MAV_4867|M.avium_104 ALAPSVATPAGAPASTVAAGSGAAAAPGP-AAAAGN--FAYLVAFGGDPD MAB_2230c|M.abscessus_ATCC_199 FAMGGMPGGGGAPATPANAPATPANAPASPAAAAATPAYMVYAVQEDPPA MLBr_01991|M.leprae_Br4923 VAPPASATSSGNSYTSNSAPSTSASATTDNPLSSPS--IRYAIPGLSPPE . TH_3569|M.thermoresistible__bu -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 EGFTPTLGNKSQVAAPASGVPAAASGVAASLASRRKRRRKKGAQIEERGY Mflv_0325|M.gilvum_PYR-GCK EGFSPTVRDSTGAKAPAGTIPAAASGIAASAAERRKRRRRQKEEIKGRGY Mvan_0415|M.vanbaalenii_PYR-1 TGFSPTVRDSTSAKAPASGIPAAASGVAASAAERRKRRRRQKDEIAGRAY Mb0294|M.bovis_AF2122/97 PSLGPTVGGRGGIKAPAATVPAAAAAAATRGQSRARRRRRS----ELRDY Rv0286|M.tuberculosis_H37Rv PSLGPTVGGRGGIKAPAATVPAAAAAAATRGQSRARRRRRS----ELRDY MMAR_0545|M.marinum_M PSLGPTVGGRSGAKAPAATIPAAGAAAASRASARSRRRRRT----EMRDY MUL_1208|M.ulcerans_Agy99 PSLGPTVGGRSGAKAPAVTIPAAGAAAASRASARSRRRRRT----EMRDY MAV_4867|M.avium_104 TGVGPTLSGRGGAKAPAATIPAAGAAAPARAEARARRRRRA----ALHDY MAB_2230c|M.abscessus_ATCC_199 ARFGPTLNEGSGAKAPAAGISAAAAAAAS-ARSRARRKRGAR----IKDP MLBr_01991|M.leprae_Br4923 VSSGPKAGTKS-PDTATNTIGITAAARTNSPSARAHRKRGNKTRGGARGY TH_3569|M.thermoresistible__bu -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 ADAYMDYEE----PDEDPAPQPEPRVRASERGSDAMGFTGTVTRHD-VTA Mflv_0325|M.gilvum_PYR-GCK ADAYADYEEL---PDDGPPEQPAPRVTASTRGAGPMGFAGTVSRGD-EQA Mvan_0415|M.vanbaalenii_PYR-1 ADAYADYEPE---PDDEPPVRQEPRIAATERGAGPMGFAGTVSRDA-AQA Mb0294|M.bovis_AF2122/97 GDEFLDMDS----DSGFGPSTGDHGAQASERGAGTLGFAGTATKERRVRA Rv0286|M.tuberculosis_H37Rv GDEFLDMDS----DSGFGPSTGDHGAQASERGAGTLGFAGTATKERRVRA MMAR_0545|M.marinum_M GDEFLDMDA----NGVTGPAATDDAARASERGAGQFGFAGTVSTEAVLQA MUL_1208|M.ulcerans_Agy99 GDEFLDMDA----NGVTGPAATDDAARASERGAGQFGFAGTVSTEAVLQA MAV_4867|M.avium_104 SDEFLDMDSGFGVPPDYGAEEELAAAVASGQGAGTLGFAGTQQRRKAFQA MAB_2230c|M.abscessus_ATCC_199 APQFMDMNSPVDPDFSEPATRHTAGVGASGRGAGQLGFAGTLPRTTSTTS MLBr_01991|M.leprae_Br4923 RYEFVEGTATMADTVDAPDHSEPTSHTISNHSAGPIGFAGTVPTTA---- TH_3569|M.thermoresistible__bu -------------------------------------------------- MSMEG_0619|M.smegmatis_MC2_155 AG--LTTLTGDTFDDRPVTPMLPGTWDGD--ENPA------PSPDDPEGG Mflv_0325|M.gilvum_PYR-GCK GG--LTTLAGDSFGGGPREPMLPGTWDPD--ATDDRHTDGRDGHDGHDGK Mvan_0415|M.vanbaalenii_PYR-1 GG--LTTLPGDPFGGGPKAPMLPGTWDPD--TEPD------ERHNHHDGK Mb0294|M.bovis_AF2122/97 VG--LTALAGDEFGNGPRMPMVPGTWEQGSNEPEAPDGSGRGGGDGLPHD Rv0286|M.tuberculosis_H37Rv VG--LTALAGDEFGNGPRMPMVPGTWEQGSNEPEAPDGSGRGGGDGLPHD MMAR_0545|M.marinum_M AG--LTELAVDEFGNGPRMPMVPGSWDS----PQE------GREDGLQSE MUL_1208|M.ulcerans_Agy99 AG--LTELAVDEFGNGPRMPMVPGSWDS----PQE------GREDGLQSE MAV_4867|M.avium_104 AG--LTKLADDDFGGSPRMPMVPGTWEQD---TQN------GAHPTEPGK MAB_2230c|M.abscessus_ATCC_199 AAGLIEREAASEMDGTRTVPMLPTSWGTDPEPDPDRAPSVPAPDEDWPPG MLBr_01991|M.leprae_Br4923 -----STPTGMAASTSSSVPLLPTTWITG-------------TSETAVHE TH_3569|M.thermoresistible__bu ------ MSMEG_0619|M.smegmatis_MC2_155 PRR--- Mflv_0325|M.gilvum_PYR-GCK EKP--- Mvan_0415|M.vanbaalenii_PYR-1 DSQ--- Mb0294|M.bovis_AF2122/97 SK---- Rv0286|M.tuberculosis_H37Rv SK---- MMAR_0545|M.marinum_M ------ MUL_1208|M.ulcerans_Agy99 ------ MAV_4867|M.avium_104 GG---- MAB_2230c|M.abscessus_ATCC_199 ERGAST MLBr_01991|M.leprae_Br4923 ------