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M. thermoresistible (build 8) TH_3569 (-)

annotation: PPE protein
coordinates: 2683333 - 2684361
length: 343

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3569--100% (343)PPE protein
M. thermoresistible (build 8)TH_3113-9e-6543.63% (353) PUTATIVE PPE protein
M. thermoresistible (build 8)TH_4447-1e-3843.69% (206) PUTATIVE PPE protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0294PPE46e-9555.02% (329) PPE family protein
M. gilvum PYR-GCKMflv_0325-1e-11060.95% (338) PPE protein
M. tuberculosis H37RvRv0286PPE46e-9555.02% (329) PPE family protein
M. leprae Br4923MLBr_01991PPE4e-6044.67% (300) PPE-family protein
M. abscessus ATCC 19977MAB_2230c-1e-9253.15% (333) PPE family protein
M. marinum MMMAR_0545-1e-9555.76% (330) PPE family protein, PPE4
M. avium 104MAV_4867-8e-8653.02% (315) PPE family protein
M. smegmatis MC2 155MSMEG_0619-1e-13270.41% (338) PPE family protein
M. ulcerans Agy99MUL_1208-2e-9555.45% (330) PPE family protein
M. vanbaalenii PYR-1Mvan_0415-1e-11562.57% (342) PPE protein

CLUSTAL 2.0.9 multiple sequence alignment


TH_3569|M.thermoresistible__bu      ---------MMTAPIWMALPPEVHSALLSSGPGPGSLLAAASAWHALSAE
MSMEG_0619|M.smegmatis_MC2_155      ----------MTAPIWMALPPEVHSSLLSSGPGPGSLLAAAGAWQSLSAE
Mflv_0325|M.gilvum_PYR-GCK          MTSPVASLAPVTSPVWMALPPEVHSTMLSSGPGPGSLLAAGVAWQSLSAE
Mvan_0415|M.vanbaalenii_PYR-1       ----------MSSPVWMALPPEVHSALLSSGPGPGSMLAAAATWQSLSAE
Mb0294|M.bovis_AF2122/97            ----------MAAPIWMASPPEVHSALLSNGPGPGSLVAAATAWSQLSAE
Rv0286|M.tuberculosis_H37Rv         ----------MAAPIWMASPPEVHSALLSNGPGPGSLVAAATAWSQLSAE
MMAR_0545|M.marinum_M               -------MAVAAGPIWIASPPEVHSAMLSSGPGPASLLAAAGVWSALSAE
MUL_1208|M.ulcerans_Agy99           -------MAVAAGPIWIASPPEVHSAMLSSGPGPASLLAAAGVWSALSAE
MAV_4867|M.avium_104                -------MTSPFGPIWMASPPEVHSALLSAGPGPGPLLAAAGAWTSLSAQ
MAB_2230c|M.abscessus_ATCC_199      ----------MSAPIWMASPPEVHSALLSAGPGPGALLAAAAQWQALSVQ
MLBr_01991|M.leprae_Br4923          ----------------MAIPPEVHSVLLSAGQGAESLLVAATQWQELSKQ
                                                    :* ****** :** * *. .::.*.  *  ** :

TH_3569|M.thermoresistible__bu      YASAAAELSSVLANVQAGSWEGPSAERYVAAHAPYLAWLTQQSANSAATA
MSMEG_0619|M.smegmatis_MC2_155      YAAAAAELTSVLSAVQAGSWEGPSSEQYVAAHAPYLQWLAQQSANSAAAA
Mflv_0325|M.gilvum_PYR-GCK          YASAAAELTSILAGVQSGAWEGPSSQQYVAAHTPYLAWLAQQSAVSAATA
Mvan_0415|M.vanbaalenii_PYR-1       YAAAAAELSSILADVQAGAWEGPSSEQYVAAHTPYLAWLAQQSAAGAAAA
Mb0294|M.bovis_AF2122/97            YASTAAELSGLLGAVPGWAWQGPSAEWYVAAHLPYVAWLTQASADAAGAA
Rv0286|M.tuberculosis_H37Rv         YASTAAELSGLLGAVPGWAWQGPSAEWYVAAHLPYVAWLTQASADAAGAA
MMAR_0545|M.marinum_M               YALTAAELSEVLAAVQAGAWQGPSGFQYVAAHLPYVAWLLQASADGAGKA
MUL_1208|M.ulcerans_Agy99           YALTAAELSEVLAAVQAGAWQGPSGFQYVAAHLPYVAWLLQASADGAGKA
MAV_4867|M.avium_104                YATAAAELSALLGEAQAGSWEGESAAQYAAAHLPYLAWLQQASADSAGAA
MAB_2230c|M.abscessus_ATCC_199      YTTAATELTQLLAATGSGSWQGPSAAQYVASHAPYLAWLTQQSAMSATNA
MLBr_01991|M.leprae_Br4923          YTYAAAELTRLLTHVQATSWRGTSATRFVAAHGAYLVWLEQTSINNAITA
                                    *: :*:**: :*  . . :*.* *.  :.*:* .*: ** * *   *  *

TH_3569|M.thermoresistible__bu      GRHETAAAAYSTALATMPTMAELTLNKTTHAVLVATNFLGINTIPIALNE
MSMEG_0619|M.smegmatis_MC2_155      VQHETAAAAYSTALATMPTMAELALNHTMHGVLVATNFFGINTIPIALNE
Mflv_0325|M.gilvum_PYR-GCK          VQHDTAAAAYTTALATMPTLPELALNHTTHAVLVGTNFLGINTIPIALNE
Mvan_0415|M.vanbaalenii_PYR-1       AQHEAAAAAYSTALATMPTLPELALNHTTHAVLVATNFLGINTIPIAMTE
Mb0294|M.bovis_AF2122/97            AQHEAAAAAYTTALAAMPTLAELAANHVIHTVLVATNFFGINTIPITLNE
Rv0286|M.tuberculosis_H37Rv         AQHEAAAAAYTTALAAMPTLAELAANHVIHTVLVATNFFGINTIPITLNE
MMAR_0545|M.marinum_M               AEHEAAAVAYSGALAAMPTLTELGANHALHGVLVATNFFGLNAIPIALNE
MUL_1208|M.ulcerans_Agy99           AEHEAAAVAYSGALAAMPTLTELGANHALHGVLVATNFFGLNAIPIALNE
MAV_4867|M.avium_104                AQQEVAATAYTTALAAMPTLAELAANHTIHGVLLATNFFGINTIPIAVNE
MAB_2230c|M.abscessus_ATCC_199      VLHETSAAAYTTALAAMPTLAELAANHMIHGVLLATNFFGINTIPIALNE
MLBr_01991|M.leprae_Br4923          KQHEIAAIAYSSALAAMPTLAELTANRATRGFLIATNFFGINTIPIALNE
                                      :: :* **: ***:***:.**  *:  : .*:.***:*:*:***::.*

TH_3569|M.thermoresistible__bu      ADYVRMWIQAATSMSTYQAVAGTAVMSAPASSPAPLLLAPGVS-EAADAM
MSMEG_0619|M.smegmatis_MC2_155      ADYVRMWIQAATTMSTYQAVSGAAVAAAPVSAPAPFLLKPGVG-EAGSAS
Mflv_0325|M.gilvum_PYR-GCK          ADYVRMWIQAATTMATYQSVSGAALAATPTSAPAPSVLLPGVG-EAGRAA
Mvan_0415|M.vanbaalenii_PYR-1       ADYVRMWIQAATTMATYQAVSGAALAATPTATPAPFVLAPGVG-EAGRAA
Mb0294|M.bovis_AF2122/97            ADYVRMWLQAAAVMGLYQAASGAALASAPRTVPAPTVMNPGGG-------
Rv0286|M.tuberculosis_H37Rv         ADYVRMWLQAAAVMGLYQAASGAALASAPRTVPAPTVMNPGGG-------
MMAR_0545|M.marinum_M               ADYVRMWVQAATTMGLYQATAGAALASAPRTGPPPKVVNPGGGQVAHLAA
MUL_1208|M.ulcerans_Agy99           ADYVRMWVQAATTMGLYQATAGAALASAPRTGPPPKVVNPGGGQVAHLAA
MAV_4867|M.avium_104                ADYARMWVQAATTMGTYQAVAGSALAAAPRTAPAPSIVKPGGE-------
MAB_2230c|M.abscessus_ATCC_199      ADYIRMWIQAATTMGVYQGVSTAAVTSVAPTPPAPTIMAPGGE--MSRMS
MLBr_01991|M.leprae_Br4923          ADYVRMWVQAADTMATYQAISEAVTATILPTQVAPPILAPGSA-------
                                    *** ***:***  *. **. : :.  :   :  .* :: **         

TH_3569|M.thermoresistible__bu      ATTQQIGSQATAADSGTAL-NLSDLIANLLQYYQDYLDQLFGPIVDFLRD
MSMEG_0619|M.smegmatis_MC2_155      ASVQQMSAQATAAESGSSL-DLSSIISDLLNQYLQGVPGGQ-AILDFLKD
Mflv_0325|M.gilvum_PYR-GCK          ADMSAFAAQPMAAQAGAAF-DVSNIIADIIRLYGEVLRFLFEPIFNFLRD
Mvan_0415|M.vanbaalenii_PYR-1       ADVTAFAAQAQAAEAGSAL-DLSNIIADLIRAYGELLRFLFEPIFDFLRD
Mb0294|M.bovis_AF2122/97            -------AASTVGAVNPWQ-WLLALLQQLWNAYTGFYGWMLQLIWQFLQD
Rv0286|M.tuberculosis_H37Rv         -------AASTVGAVNPWQ-WLLALLQQLWNAYTGFYGWMLQLIWQFLQD
MMAR_0545|M.marinum_M               DAAQAQSGAAAAGGSDPWQ-LLWQLLQYLWNAYTGFNTWMFDLIWEFLQD
MUL_1208|M.ulcerans_Agy99           DAARAQSGAAAAGGSDPWQ-LLWQLLQYLWNAYTGFNTWMFDLIWEFLQD
MAV_4867|M.avium_104                ----ANNLAANAAQNSSGD-WWQNFIQQLS---------------QFFQN
MAB_2230c|M.abscessus_ATCC_199      ADMSGMAAQAQAAESGMALDDSESFFDKLMR-----------QIQEFFSD
MLBr_01991|M.leprae_Br4923          --------TQNVLQS------VPDWIVQLLT-----------DILDFIAD
                                               .             :  :                :*: :

TH_3569|M.thermoresistible__bu      PIGNLFQLIDDFLTNPAGALVTWWPLLFAVAYQVFTNLVGWPTWAMILAS
MSMEG_0619|M.smegmatis_MC2_155      PLGNLGRLLTDFMTNPAGALATWWPFLFGVAYQVFFNLVGWPTWGMIFAS
Mflv_0325|M.gilvum_PYR-GCK          PIGNTFALITDFLTNPVQALITWGPFLLAVVYQAVSWVGASILYPSLFLL
Mvan_0415|M.vanbaalenii_PYR-1       PLGNTIKLITDFLTNPAQALITWGPFLAAVAYQAVSWVGASILYPSLLLL
Mb0294|M.bovis_AF2122/97            PIGNSIKIIIAFLTNPIQALITYGPLLFALGYQIFFNLVGWPTWGMILSS
Rv0286|M.tuberculosis_H37Rv         PIGNSIKIIIAFLTNPIQALITYGPLLFALGYQIFFNLVGWPTWGMILSS
MMAR_0545|M.marinum_M               PIGNTIKIIIAFLTNPLQAIITYGPLLFALSYQIFFNLVGWPTWALILSS
MUL_1208|M.ulcerans_Agy99           PIGNTIKIIIAFLTNPLQAIITYGPLLFALSYQIFFNLVGWPTWALILSS
MAV_4867|M.avium_104                ----IQKMLQDFWANLPAFLAANGPLLFFVAYQVFFNAVGWPTWGAILTA
MAB_2230c|M.abscessus_ATCC_199      PLGTLQKILQDFMRNPLEALVAWGPLLFFIAYEAFFIPFGFTFWGVMLSA
MLBr_01991|M.leprae_Br4923          PYKYFLRFFQRLGFRPAIAVVLA---IIALQLYDFLWYPYYASYG-MLLL
                                           ::  :  .    :      :  :    .        :  ::  

TH_3569|M.thermoresistible__bu      PVLIPLAITLGVAGLVMIADQAQP-----PAEEAAPEEDVAAP-------
MSMEG_0619|M.smegmatis_MC2_155      PFLIPALAALGITGLVLLIDHVLNNPVDVPAEDEAPQEVAAAPRTDQPLA
Mflv_0325|M.gilvum_PYR-GCK          PLLATTLAIVAGVGQHLLSLLNTP-PAEEAAEEPAPAQSAPSRPDQQSFP
Mvan_0415|M.vanbaalenii_PYR-1       PLVATTLAIVLGVGAYLLENLPAP-AEDAPAEEPAASSPAPTRADQPSPA
Mb0294|M.bovis_AF2122/97            PFLLPAGLGLGLAAIAFLPIVLAP--AVIPPASTPLAAAAVAAGSVWPAV
Rv0286|M.tuberculosis_H37Rv         PFLLPAGLGLGLAAIAFLPIVLAP--AVIPPASTPLAAAAVAAGSVWPAV
MMAR_0545|M.marinum_M               PFLLPAALGLALSAIAFTPIQIA---AEVPAAAAPLAAAAVTAKSVFPAA
MUL_1208|M.ulcerans_Agy99           PFLLPAALGLALSAIAFTPIQIA---AEVPAAAAPLAAAAVTAKSVFPAA
MAV_4867|M.avium_104                PFLLPLLLGIGLSSLLAAPAEIAP--VAAPAAITPVLASNKPP-TLPAAV
MAB_2230c|M.abscessus_ATCC_199      PLWLPLLL-VGLAQLVNPVPVEAD----APADEPAPQQARVERSSPQQQP
MLBr_01991|M.leprae_Br4923          PFFAPALSVLGTLSVLWNGQLSAG-----LPPNPAGSHPDNNAGPRIHVG
                                    *.  .    :                    .   .               

TH_3569|M.thermoresistible__bu      ------------VRAEPQNPLPLTXXX-----------------------
MSMEG_0619|M.smegmatis_MC2_155      VGISPAGVPGSAATAAAPAPAPAGTTVAAPAPAAAT--FVPYAVANRDPG
Mflv_0325|M.gilvum_PYR-GCK          ATMSAPPPPSGAPIAANTVSAGSPPAPGAPAAAAAT--FVPYVVAGRDPY
Mvan_0415|M.vanbaalenii_PYR-1       IAVSAPPPPSSAAATVGTVATGTAPAPGAPAAATAS--FVPYAVAGRDPG
Mb0294|M.bovis_AF2122/97            SMAVTGAGTAGAATPAAGAAPSAGAAPAPAAPATAS--FAYAVGGSGDWG
Rv0286|M.tuberculosis_H37Rv         SMAVTGAGTAGAATPAAGAAPSAGAAPAPAAPATAS--FAYAVGGSGDWG
MMAR_0545|M.marinum_M               SLASPGTGSAGAPASGAGAGAPGSAPPGPAAPAPAS--FLYAVGGSGDWG
MUL_1208|M.ulcerans_Agy99           SLASPGTGSAGAPASGAGAGAPGTAPPGPGAPAPAS--FLYAVGGSGDWG
MAV_4867|M.avium_104                ALAPSVATPAGAPASTVAAGSGAAAAPGP-AAAAGN--FAYLVAFGGDPD
MAB_2230c|M.abscessus_ATCC_199      FAMGGMPGGGGAPATPANAPATPANAPASPAAAAATPAYMVYAVQEDPPA
MLBr_01991|M.leprae_Br4923          VAPPASATSSGNSYTSNSAPSTSASATTDNPLSSPS--IRYAIPGLSPPE
                                                  .                                   

TH_3569|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0619|M.smegmatis_MC2_155      EGFTPTLGNKSQVAAPASGVPAAASGVAASLASRRKRRRKKGAQIEERGY
Mflv_0325|M.gilvum_PYR-GCK          EGFSPTVRDSTGAKAPAGTIPAAASGIAASAAERRKRRRRQKEEIKGRGY
Mvan_0415|M.vanbaalenii_PYR-1       TGFSPTVRDSTSAKAPASGIPAAASGVAASAAERRKRRRRQKDEIAGRAY
Mb0294|M.bovis_AF2122/97            PSLGPTVGGRGGIKAPAATVPAAAAAAATRGQSRARRRRRS----ELRDY
Rv0286|M.tuberculosis_H37Rv         PSLGPTVGGRGGIKAPAATVPAAAAAAATRGQSRARRRRRS----ELRDY
MMAR_0545|M.marinum_M               PSLGPTVGGRSGAKAPAATIPAAGAAAASRASARSRRRRRT----EMRDY
MUL_1208|M.ulcerans_Agy99           PSLGPTVGGRSGAKAPAVTIPAAGAAAASRASARSRRRRRT----EMRDY
MAV_4867|M.avium_104                TGVGPTLSGRGGAKAPAATIPAAGAAAPARAEARARRRRRA----ALHDY
MAB_2230c|M.abscessus_ATCC_199      ARFGPTLNEGSGAKAPAAGISAAAAAAAS-ARSRARRKRGAR----IKDP
MLBr_01991|M.leprae_Br4923          VSSGPKAGTKS-PDTATNTIGITAAARTNSPSARAHRKRGNKTRGGARGY
                                                                                      

TH_3569|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0619|M.smegmatis_MC2_155      ADAYMDYEE----PDEDPAPQPEPRVRASERGSDAMGFTGTVTRHD-VTA
Mflv_0325|M.gilvum_PYR-GCK          ADAYADYEEL---PDDGPPEQPAPRVTASTRGAGPMGFAGTVSRGD-EQA
Mvan_0415|M.vanbaalenii_PYR-1       ADAYADYEPE---PDDEPPVRQEPRIAATERGAGPMGFAGTVSRDA-AQA
Mb0294|M.bovis_AF2122/97            GDEFLDMDS----DSGFGPSTGDHGAQASERGAGTLGFAGTATKERRVRA
Rv0286|M.tuberculosis_H37Rv         GDEFLDMDS----DSGFGPSTGDHGAQASERGAGTLGFAGTATKERRVRA
MMAR_0545|M.marinum_M               GDEFLDMDA----NGVTGPAATDDAARASERGAGQFGFAGTVSTEAVLQA
MUL_1208|M.ulcerans_Agy99           GDEFLDMDA----NGVTGPAATDDAARASERGAGQFGFAGTVSTEAVLQA
MAV_4867|M.avium_104                SDEFLDMDSGFGVPPDYGAEEELAAAVASGQGAGTLGFAGTQQRRKAFQA
MAB_2230c|M.abscessus_ATCC_199      APQFMDMNSPVDPDFSEPATRHTAGVGASGRGAGQLGFAGTLPRTTSTTS
MLBr_01991|M.leprae_Br4923          RYEFVEGTATMADTVDAPDHSEPTSHTISNHSAGPIGFAGTVPTTA----
                                                                                      

TH_3569|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0619|M.smegmatis_MC2_155      AG--LTTLTGDTFDDRPVTPMLPGTWDGD--ENPA------PSPDDPEGG
Mflv_0325|M.gilvum_PYR-GCK          GG--LTTLAGDSFGGGPREPMLPGTWDPD--ATDDRHTDGRDGHDGHDGK
Mvan_0415|M.vanbaalenii_PYR-1       GG--LTTLPGDPFGGGPKAPMLPGTWDPD--TEPD------ERHNHHDGK
Mb0294|M.bovis_AF2122/97            VG--LTALAGDEFGNGPRMPMVPGTWEQGSNEPEAPDGSGRGGGDGLPHD
Rv0286|M.tuberculosis_H37Rv         VG--LTALAGDEFGNGPRMPMVPGTWEQGSNEPEAPDGSGRGGGDGLPHD
MMAR_0545|M.marinum_M               AG--LTELAVDEFGNGPRMPMVPGSWDS----PQE------GREDGLQSE
MUL_1208|M.ulcerans_Agy99           AG--LTELAVDEFGNGPRMPMVPGSWDS----PQE------GREDGLQSE
MAV_4867|M.avium_104                AG--LTKLADDDFGGSPRMPMVPGTWEQD---TQN------GAHPTEPGK
MAB_2230c|M.abscessus_ATCC_199      AAGLIEREAASEMDGTRTVPMLPTSWGTDPEPDPDRAPSVPAPDEDWPPG
MLBr_01991|M.leprae_Br4923          -----STPTGMAASTSSSVPLLPTTWITG-------------TSETAVHE
                                                                                      

TH_3569|M.thermoresistible__bu      ------
MSMEG_0619|M.smegmatis_MC2_155      PRR---
Mflv_0325|M.gilvum_PYR-GCK          EKP---
Mvan_0415|M.vanbaalenii_PYR-1       DSQ---
Mb0294|M.bovis_AF2122/97            SK----
Rv0286|M.tuberculosis_H37Rv         SK----
MMAR_0545|M.marinum_M               ------
MUL_1208|M.ulcerans_Agy99           ------
MAV_4867|M.avium_104                GG----
MAB_2230c|M.abscessus_ATCC_199      ERGAST
MLBr_01991|M.leprae_Br4923          ------