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VSFFVLPPEINSLRMFIGAGTAPMLEAAAAWQGLAEELSTAAQSFASVTAGLAGQAWQGSAAMAMASAAA PYAGWLAAAAAQSAGAAGNARAVASMFEAAQAATVLPTSISANRNAFVQLVMSNLFGQNAPAIAAAESIY EEMWAADVAAMSGYYSGVSAVAAQVVPWQSVLKGLPGLASGLAGGAGAGSGFAGGSGMVGGAAGSPGSQG GAGAGSDTAGANAGGDASSSVVAGGGAGGAGLVGAGGYASGGGGADSGAMGAPGGAVDGASSGVGGGGGG MAASAGAATPGMGAMAMPIAGMAAARAAMAAGGGQSGPVNAGPPVRETAPAAPEPEAAAPAPEEAEAPVP QMAVLPTADPGIAAAAAPGSKPQATRATGTTGIPASPLRSSPAGTESKRSAPTQDQQDGAEQTAAEDTVV PLRPEAVAGELRSRVQEPSGIQMRGG
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_1484 | - | - | 100% (446) | PPE family protein |
M. marinum M | MMAR_4554 | - | 3e-77 | 52.29% (306) | PPE family protein |
M. marinum M | MMAR_1469 | - | 5e-76 | 48.79% (330) | PPE family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3168c | PPE52 | 1e-120 | 58.00% (450) | PPE-family protein |
M. gilvum PYR-GCK | Mflv_0768 | - | 4e-22 | 28.39% (391) | PPE protein |
M. tuberculosis H37Rv | Rv3144c | PPE52 | 1e-119 | 57.78% (450) | PPE family protein |
M. leprae Br4923 | MLBr_01182 | - | 3e-29 | 42.95% (156) | PPE-family protein |
M. abscessus ATCC 19977 | MAB_0669 | - | 1e-21 | 33.74% (163) | PPE-family protein |
M. avium 104 | MAV_1998 | - | 2e-52 | 36.02% (422) | PPE family protein |
M. smegmatis MC2 155 | MSMEG_0064 | - | 1e-24 | 27.92% (437) | PPE family protein |
M. thermoresistible (build 8) | TH_3569 | - | 6e-22 | 32.80% (186) | PUTATIVE PPE protein |
M. ulcerans Agy99 | MUL_3169 | - | 6e-69 | 47.84% (324) | PPE family protein |
M. vanbaalenii PYR-1 | Mvan_0077 | - | 4e-22 | 28.13% (423) | PPE protein |
CLUSTAL 2.0.9 multiple sequence alignment Mb3168c|M.bovis_AF2122/97 ---------MSFVVLPPEINSLRMFIGAGTAPMLAAAAAWDGLAEELGTA Rv3144c|M.tuberculosis_H37Rv ---------MSFVVLPPEINSLRMFIGAGTAPMLAAAAAWDGLAEELGTA MMAR_1484|M.marinum_M ---------MSFFVLPPEINSLRMFIGAGTAPMLEAAAAWQGLAEELSTA MUL_3169|M.ulcerans_Agy99 ---------MNFSVLPPEINSLRLFSDAGSTSMLEAAAAWGSLADELQVA MAV_1998|M.avium_104 ---------MDFGALPPEINSGRMYSGPGPASLLAAAAGWESLAAELADG Mflv_0768|M.gilvum_PYR-GCK MANIGIPVPPSWVAFPPEINTSRLQAGAGAVPMLQAAAGWEAFAISLETQ Mvan_0077|M.vanbaalenii_PYR-1 MATIGIPIPPIWGAFPPEINTSRLQAGAGAVPMLQAAAGWEAFAISLETQ MSMEG_0064|M.smegmatis_MC2_155 ----------MWIALPPEINTARLMVGAGPAPMLQAAAGWEGLAVLLETQ MAB_0669|M.abscessus_ATCC_1997 ------MTAPIWMAEPPEVHSALLSAGPGPGAVLAAAVQWQEIGNNYANT TH_3569|M.thermoresistible__bu -----MMTAPIWMALPPEVHSALLSSGPGPGSLLAAASAWHALSAEYASA MLBr_01182|M.leprae_Br4923 --------MFDFAALSPETNSTRMYLGPGSSPILTAAAAWVVLAKELTAA : . .** :: : ..*. .:* ** * :. Mb3168c|M.bovis_AF2122/97 AQSFASVTAGLAGQAWQGPAALAMAAAAAPYAGWLTAAAAQSAGAAGQAR Rv3144c|M.tuberculosis_H37Rv AQSFASVTAGLAGQAWQGPAALAMAAAAAPYAGWLTAAAAQSAGAAGQAR MMAR_1484|M.marinum_M AQSFASVTAGLAGQAWQGSAAMAMASAAAPYAGWLAAAAAQSAGAAGNAR MUL_3169|M.ulcerans_Agy99 ASSFSSVTAGLASGAWQGPASAAMSAVAAPYASWLSAAAAQAAGTAGRAS MAV_1998|M.avium_104 AGNYQAVIAGLTNESWLGPASLSMAGAVMPYVSWLTAVAEQCGRAAAQAT Mflv_0768|M.gilvum_PYR-GCK ADELASSLASLSQ-NWQGMASERAVTAAMPMVLWLRMLSLQAHKRALQAS Mvan_0077|M.vanbaalenii_PYR-1 ADELAASLATLSQ-MWQGTASERAVMATMPMVMWLRMLSLQAQKRAAQAS MSMEG_0064|M.smegmatis_MC2_155 AAELAAALTNLTS-VWTGAASERAVAATMPMITWLQTTAAQAQKRALQAS MAB_0669|M.abscessus_ATCC_1997 AVELAQVLAGVRAGSWQGPSASEYVAAHLPYLAWLEQAAAESSVIAAQHE TH_3569|M.thermoresistible__bu AAELSSVLANVQAGSWEGPSAERYVAAHAPYLAWLTQQSANSAATAGRHE MLBr_01182|M.leprae_Br4923 AQGLQSAVEALLT-TFEGESAAALAERVTPYEKWLTQNAASAELTATQLT * : : * :: * ** : .. * . Mb3168c|M.bovis_AF2122/97 AVASIFEAAQAATVLPAAVAANRDAFVQLVMTNLFGQNAPLIAAAEGVY- Rv3144c|M.tuberculosis_H37Rv AVASIFEAAQAATVLPAAVAANRDAFVQLVMTNLFGQNAPLIAAAEGVY- MMAR_1484|M.marinum_M AVASMFEAAQAATVLPTSISANRNAFVQLVMSNLFGQNAPAIAAAESIY- MUL_3169|M.ulcerans_Agy99 AAAAVFEAAQAAIVHPAMVAANRNELVALVISNLFGQNAPAIAATEAVY- MAV_1998|M.avium_104 AAASAFEAAYAMTVPPPLIAANRARLLALVQSNIFGQNTPAIMATEAEY- Mflv_0768|M.gilvum_PYR-GCK AQASSWTVAATGTPQLPEIELNHVTNATLHATNFLGVNGIPIALNEADY- Mvan_0077|M.vanbaalenii_PYR-1 AQATAWASAATSTPQLPEIETNHITNAVLNATNFLGVNTVPIAVNEADY- MSMEG_0064|M.smegmatis_MC2_155 AQASSYSLALATTPPLPEIEQNHITHGVLEATNFLGINTVPIALNEMDYF MAB_0669|M.abscessus_ATCC_1997 TTAAAYNSALAAMPTLAELAANHITHGVLVGTNFFGINTIPIALNEADY- TH_3569|M.thermoresistible__bu TAAAAYSTALATMPTMAELTLNKTTHAVLVATNFLGINTIPIALNEADY- MLBr_01182|M.leprae_Br4923 VAANAYETAFTMTVPPLMVFVNRAQACLLIMSNIFGQNSTAIAEKEAEY- . * : * : : *: * :*::* * * * * Mb3168c|M.bovis_AF2122/97 EEMWAADVAAMSGYYSGASAIAAQVVPWASLLQR---------------- Rv3144c|M.tuberculosis_H37Rv EEMWAADVAAMSGYYSGASAIAAQVVPWASLLQR---------------- MMAR_1484|M.marinum_M EEMWAADVAAMSGYYSGVSAVAAQVVPWQSVLKG---------------- MUL_3169|M.ulcerans_Agy99 EQLWAQDVAVMAGYHAGVSAIAQQLAPWQQALALPAADADFSLSIFGLQL MAV_1998|M.avium_104 SEMWAQDATAMYG-YAANSASASALSPVPSPPQP---------------- Mflv_0768|M.gilvum_PYR-GCK IRMWNQAAAVMTAYETETVLNTTFEPVAPPKPIA---------------- Mvan_0077|M.vanbaalenii_PYR-1 IRMWNQAAAVMTGYETETILNSTFEPVAPPKPIT---------------- MSMEG_0064|M.smegmatis_MC2_155 VRMWNQAAGAMDVYHAETTVNLLFEPIMPMKPIV---------------- MAB_0669|M.abscessus_ATCC_1997 VRMWVQAAATMSAYQATTEAMTSAIPPTQQPPAI---------------- TH_3569|M.thermoresistible__bu VRMWIQAATSMSTYQAVAGTAVMSAPASSPAPLL---------------- MLBr_01182|M.leprae_Br4923 TEMWIQDAAAMTSYQASVLEAVGATKAFTAPPLG---------------- .:* . * : Mb3168c|M.bovis_AF2122/97 -----------FPGLGAG------------------ATGATGGES---VG Rv3144c|M.tuberculosis_H37Rv -----------FPGLGAG------------------ATGATGGES---VG MMAR_1484|M.marinum_M -----------LPGLASG------------------LAGGAGAGSGFAGG MUL_3169|M.ulcerans_Agy99 VKTGTANATTTFGGLAIASGANSSADAGVADIAFAFGSGSSASATGGVLN MAV_1998|M.avium_104 -----------TNPAAAG---------------HLAAAAHAAVQSGSSAH Mflv_0768|M.gilvum_PYR-GCK ------------------------------------VPPGSEAAFAGAMS Mvan_0077|M.vanbaalenii_PYR-1 ------------------------------------VFGSTQAAMATAIG MSMEG_0064|M.smegmatis_MC2_155 ------------------------------------LPGVGETTAAAALA MAB_0669|M.abscessus_ATCC_1997 ------------------------------------LSPGGEARSDQSDV TH_3569|M.thermoresistible__bu ------------------------------------LAPG---VSEAADA MLBr_01182|M.leprae_Br4923 --------------------------------------VNEVGLAQEVVE Mb3168c|M.bovis_AF2122/97 TGATGGES--VGTGGGE----SVG-------------------------- Rv3144c|M.tuberculosis_H37Rv TGATGGES--VGTGGGE----SVG-------------------------- MMAR_1484|M.marinum_M SGMVGGAAGSPGSQGGA----GAGS------------------------- MUL_3169|M.ulcerans_Agy99 IAGVGGANSSASATGGI----NIGTGALAVGDGNTVNASSIGVANIGTVA MAV_1998|M.avium_104 TTTAHWMSSVPQTLQGLSTPG----------------------------- Mflv_0768|M.gilvum_PYR-GCK GAVPGAGEAVMRN------------------------------------- Mvan_0077|M.vanbaalenii_PYR-1 SAAPGIASAAARN------------------------------------- MSMEG_0064|M.smegmatis_MC2_155 QTAPRVAEGVMRN------------------------------------- MAB_0669|M.abscessus_ATCC_1997 PGSPDQIMKMLQGFQQW--------------------------------- TH_3569|M.thermoresistible__bu MATTQQIGSQAT-------------------------------------- MLBr_01182|M.leprae_Br4923 EVVEEVVEEVVEA------------------------------------- Mb3168c|M.bovis_AF2122/97 -------------------------------------------------- Rv3144c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1484|M.marinum_M -------------------------------------------------- MUL_3169|M.ulcerans_Agy99 AAFGNNSVTAIANGVENNATVAAAFGNNNTDVSAIVNGVENTGVVSAVFG MAV_1998|M.avium_104 -------------------------------------------------- Mflv_0768|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0077|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0064|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3569|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mb3168c|M.bovis_AF2122/97 -------------------------------------------------- Rv3144c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1484|M.marinum_M -------------------------------------------------- MUL_3169|M.ulcerans_Agy99 SDNSGVSANAFGVENNAIVATAAGSGNSNVMANAGGVGANEILVAAALGN MAV_1998|M.avium_104 -------------------------------------------------- Mflv_0768|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0077|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0064|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3569|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mb3168c|M.bovis_AF2122/97 -------------------------------------------------T Rv3144c|M.tuberculosis_H37Rv -------------------------------------------------T MMAR_1484|M.marinum_M ------------------------------------------------DT MUL_3169|M.ulcerans_Agy99 NNSAIANATGVGGTLGTGAISLIGNNNTLYADATGAGHIGTVASALFGDN MAV_1998|M.avium_104 ------------------------------------------------ST Mflv_0768|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0077|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0064|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3569|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mb3168c|M.bovis_AF2122/97 GGATASG------------GGVG--------------------------- Rv3144c|M.tuberculosis_H37Rv GGATASG------------GGVG--------------------------- MMAR_1484|M.marinum_M AGANAGGDASSSVVAGGGAGGAG--------------------------- MUL_3169|M.ulcerans_Agy99 NGVKATSFGLNNIATVATAGGSGNTTVAAEASGAENVAVLATAFGNNNPT MAV_1998|M.avium_104 PGNGLSP------------TAMG--------------------------- Mflv_0768|M.gilvum_PYR-GCK -------------------------------------------------A Mvan_0077|M.vanbaalenii_PYR-1 -------------------------------------------------A MSMEG_0064|M.smegmatis_MC2_155 -------------------------------------------------A MAB_0669|M.abscessus_ATCC_1997 -----------------------------------------------FEK TH_3569|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mb3168c|M.bovis_AF2122/97 ----YVGGG-VASAGLAAGDP----------------AHGSVGQGNFGGG Rv3144c|M.tuberculosis_H37Rv ----YVGSG-VASAGLAAGDP----------------AHGSVGQGNFGGG MMAR_1484|M.marinum_M ----LVGAGGYASGGGGADSG----------------AMGAPG-GAVDGA MUL_3169|M.ulcerans_Agy99 VTANVLGAGNLATAATALGNNNTINANVVGLENIATVATAGGNDNGVGAS MAV_1998|M.avium_104 -----TGAALGSSGPFSSLSS----------------LTGASGKGATKSA Mflv_0768|M.gilvum_PYR-GCK IISKVSSTAKLDTANQIAGRA----------------EGTLRGVVDRAGS Mvan_0077|M.vanbaalenii_PYR-1 TFTKVSVVGKLDEVNQKAGHA----------------EGLLQQAADSGRS MSMEG_0064|M.smegmatis_MC2_155 VIEGVSAIATIESVGLAAGHA----------------AAQANFAEQRGQG MAB_0669|M.abscessus_ATCC_1997 MGFNPATSAVLAVIMLFLYDL----------------LWYPYYASYLLPF TH_3569|M.thermoresistible__bu ----AADSGTALNLSDLIANL----------------LQY--YQDYLDQL MLBr_01182|M.leprae_Br4923 -----EQAISQAALDQAVNEG----------------MEATVVPQVDQQV Mb3168c|M.bovis_AF2122/97 DVGAGDVVASSATS------------------------------------ Rv3144c|M.tuberculosis_H37Rv DVGAGDVVASSATS------------------------------------ MMAR_1484|M.marinum_M SSGVGGGGGGMAAS------------------------------------ MUL_3169|M.ulcerans_Agy99 GVGVGGNIGNIATAFGNSNSQVSADASGAGGNLGTVATAFGNENNVTASA MAV_1998|M.avium_104 STGAGAGLASALAAG----------------------------------- Mflv_0768|M.gilvum_PYR-GCK HAEKSQGLEQAPQ------------------------------------- Mvan_0077|M.vanbaalenii_PYR-1 QAEQGQLLQQAPQ------------------------------------- MSMEG_0064|M.smegmatis_MC2_155 AAQKGENAGQEAGR------------------------------------ MAB_0669|M.abscessus_ATCC_1997 LIPALSGLSGLAAL------------------------------------ TH_3569|M.thermoresistible__bu FGPIVDFLR----------------------------------------- MLBr_01182|M.leprae_Br4923 NVDVATPQTAVPDSS----------------------------------- Mb3168c|M.bovis_AF2122/97 -------------------------------------------------- Rv3144c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1484|M.marinum_M -------------------------------------------------- MUL_3169|M.ulcerans_Agy99 FGAGNIGNVSSALFSNNNTISASSIGVENIGTVATSIGDNNTVSATNGLG MAV_1998|M.avium_104 -------------------------------------------------- Mflv_0768|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0077|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0064|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3569|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mb3168c|M.bovis_AF2122/97 -------------------------------------------AHAGVVS Rv3144c|M.tuberculosis_H37Rv -------------------------------------------AHAGVVS MMAR_1484|M.marinum_M -------------------------------------------AGAATPG MUL_3169|M.ulcerans_Agy99 LGGNIATVATALGGQNNTVSAETGTGGANIASVSTVLFGENNTASASAVG MAV_1998|M.avium_104 -------------------------------------------PAADGAA Mflv_0768|M.gilvum_PYR-GCK ----------------------------------------------QGMQ Mvan_0077|M.vanbaalenii_PYR-1 ----------------------------------------------QGMQ MSMEG_0064|M.smegmatis_MC2_155 -------------------------------------------ESGKNMQ MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------MHLRPAA TH_3569|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------SAAAPQL Mb3168c|M.bovis_AF2122/97 PG---------------------------------------------FIG Rv3144c|M.tuberculosis_H37Rv PG---------------------------------------------FIG MMAR_1484|M.marinum_M MG---------------------------------------------AMA MUL_3169|M.ulcerans_Agy99 AGNIANVATVSFCDNNTSNASSFGVENIAAVATSYGDGNTVTATNSLGLG MAV_1998|M.avium_104 AG----------------------------------------------LA Mflv_0768|M.gilvum_PYR-GCK MG--------------------------------------------MQMA Mvan_0077|M.vanbaalenii_PYR-1 MG--------------------------------------------MQMA MSMEG_0064|M.smegmatis_MC2_155 QG--------------------------------------------MQMV MAB_0669|M.abscessus_ATCC_1997 PG--------------------------------------------PVPA TH_3569|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 WG---------------------------------------------GFA Mb3168c|M.bovis_AF2122/97 APLA--LAALG--------QMARGGT------------NSAPGTATESAR Rv3144c|M.tuberculosis_H37Rv APLA--LAALG--------QMARGGT------------NSAPGTATESAR MMAR_1484|M.marinum_M MPIAGMAAARA--------AMAAGGG------------QSGPVNAGPPVR MUL_3169|M.ulcerans_Agy99 GNIATVATALGGQDNTVSAQAGAGGANIAQVATVLFGDNNTASASGLGAG MAV_1998|M.avium_104 EEAAGYGADGAG-------LIADGGGIG-------IDLYGLDLDYQGLAL Mflv_0768|M.gilvum_PYR-GCK SQLG---STLGQ------MPQQMMQG-----------VTQPFQQLTQPLQ Mvan_0077|M.vanbaalenii_PYR-1 SQLG---STLGQ------LPQQMMQG-----------VTQPFQQLTQPLQ MSMEG_0064|M.smegmatis_MC2_155 MQMG---SQAAQ------APAQLASM-----------FQSGVQTMTQPLQ MAB_0669|M.abscessus_ATCC_1997 AALSPGDRPIRR------PTQHVEPN-----------LAALPLPTSSVVP TH_3569|M.thermoresistible__bu -------DPIGN------LFQLIDDF-----------LTN---PAGALVT MLBr_01182|M.leprae_Br4923 QHLSPINDTLSMIN----NHAGMANAG--------LSLVNGMGSAMKSLA Mb3168c|M.bovis_AF2122/97 APEPAASAP--PEAVVEVPELEVPAMGVLPT--VDPKVAAKAAP------ Rv3144c|M.tuberculosis_H37Rv APEPAASAP--PEAVVEVPELEVPAMGVLPT--VDPKVAAKAAP------ MMAR_1484|M.marinum_M ETAPAAPEPEAAAPAPEEAEAPVPQMAVLPT--ADPGIAAAAAP------ MUL_3169|M.ulcerans_Agy99 NIADVATVLFSNNNTSTASALGVENIATIVTSYGDNNNVSATAPGIG--- MAV_1998|M.avium_104 DEAGAGSILGAEAGTGIAGTAGLGSLEPPAG--LGQGASASVGQAGA--- Mflv_0768|M.gilvum_PYR-GCK QMSSLFGGM--MNGDK-GAQIGMVGATPFSNHPAIGGTGPATGSG----- Mvan_0077|M.vanbaalenii_PYR-1 QMSSLFGQMGGLGGDR-GAQIGMLGATPFSNHPAIGGSGAATGAG----- MSMEG_0064|M.smegmatis_MC2_155 QATQMVSQFASMGGSERAMQVGLMGASPFSNHPMLGGSGPSTGAG----- MAB_0669|M.abscessus_ATCC_1997 SGGSSVPVSTPTAPAHTVSSVPAPSAAISYAIPGLVPPGVSFGPKSTEKS TH_3569|M.thermoresistible__bu ----WWPLLFAVAYQVFTNLVGWPTWAMILASPVLIPLAITLG------- MLBr_01182|M.leprae_Br4923 PTTTKAAESAFKAMGSAVQSTGRGLLGSSSGGHVTAQLGRAASIG----- . Mb3168c|M.bovis_AF2122/97 --LSTTRVGQSAG-SGIPESTLRTAQG-------------QQASETSAA- Rv3144c|M.tuberculosis_H37Rv --LSTTRVGQSAG-SGIPESTLRTAQG-------------QQASETSAA- MMAR_1484|M.marinum_M --GSKPQATRATGTTGIPASPLRSSPAGTESKRSAPTQDQQDGAEQTAA- MUL_3169|M.ulcerans_Agy99 --ANIATVATALGGQGNTVSAESGGAGANIASVSTVLFGENNTASASAVG MAV_1998|M.avium_104 --LSTLSVPPSWATTVSTVTPLPSPNSGPVPG--------GWAAAPTAS- Mflv_0768|M.gilvum_PYR-GCK -------LVRAASLPGAGGSAPQTPLMSNLVGSGLQPT-SPVAVGAGAG- Mvan_0077|M.vanbaalenii_PYR-1 -------LVRAASLPGAGGTAARTPLMSNLVGSGLQPTVSAVAVGAGAG- MSMEG_0064|M.smegmatis_MC2_155 -------LVRAMSLPGAGGTAPRTPLLSNLLG----ISGEMKAAPAGAG- MAB_0669|M.abscessus_ATCC_1997 SESAVDTVAAVAAARGAVAAQARRRLRGKNKAEAGGRRHEYLEETAGMGA TH_3569|M.thermoresistible__bu -----------VAGLVMIADQAQP-------------------------- MLBr_01182|M.leprae_Br4923 ----SLRVPQTWTTASQPVTAATRALSPARVA--------VATESESAP- Mb3168c|M.bovis_AF2122/97 ----------------EETAPSLRPEAAAGQLRPR-------VRQD---- Rv3144c|M.tuberculosis_H37Rv ----------------EETAPSLRPEAAAGQLRPR-------VRKD---- MMAR_1484|M.marinum_M ----------------EDTVVPLRPEAVAGELRSR-------VQEP---- MUL_3169|M.ulcerans_Agy99 AGNIANVATVLFSDSNTSTVSSFGVENIATVATSYGDFNNVSARTPGIGG MAV_1998|M.avium_104 ---------------PGPAVSRLPLGGMVGRESEG------PVHRVG--- Mflv_0768|M.gilvum_PYR-GCK ----------------PGAGVGLAPVGTGGGMGAGG-----PMGMFG--- Mvan_0077|M.vanbaalenii_PYR-1 ----------------AGAGAGLAPVGAGSGMGGGG-----PMGMLG--- MSMEG_0064|M.smegmatis_MC2_155 ----------------SAAAGGLAPVGAGAGGGAGA-----PVAHAG--- MAB_0669|M.abscessus_ATCC_1997 TATAD-------VPAYAATGRGTGPLGFAGTAPAAA-----STHVAA--- TH_3569|M.thermoresistible__bu -----------------------------PAEEAAP-----EEDVAA--- MLBr_01182|M.leprae_Br4923 ---------------LLGGGLPMAPMVPGGGSGTGG-------------- Mb3168c|M.bovis_AF2122/97 -------------PKIQMRGG----------------------------- Rv3144c|M.tuberculosis_H37Rv -------------PKIQMRGG----------------------------- MMAR_1484|M.marinum_M -------------SGIQMRGG----------------------------- MUL_3169|M.ulcerans_Agy99 NIATFATAFGEGNTNVHAEAGPGGANIATLATVFGDGNAVSVKSIGAGNT MAV_1998|M.avium_104 -------------QRVSLIPQVIG-------------------------- Mflv_0768|M.gilvum_PYR-GCK --------------QRGKSGGNKPGLNAPAPLDHDLGEDEDEEW------ Mvan_0077|M.vanbaalenii_PYR-1 --------------QRGKSGGNKPGLNAPAPLEHDLSEDDDDDW------ MSMEG_0064|M.smegmatis_MC2_155 --------------QNSKSGGKKDGLVAPTPLTYDLSEDEDDEW------ MAB_0669|M.abscessus_ATCC_1997 --------------TVRLSSDEARQVIPMLPSTWDADGGDQN-------- TH_3569|M.thermoresistible__bu --------------PVRAEPQNP------LPLTXXX-------------- MLBr_01182|M.leprae_Br4923 -------------VNTALRLQPRAFVMPRNPAAG---------------- Mb3168c|M.bovis_AF2122/97 -------------------------------------------------- Rv3144c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1484|M.marinum_M -------------------------------------------------- MUL_3169|M.ulcerans_Agy99 ASIATMIGNNNTADINVFGLENVATVATAIGDNNGLTANAPGLGANIATV MAV_1998|M.avium_104 -------------------------------------------------- Mflv_0768|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0077|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0064|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3569|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mb3168c|M.bovis_AF2122/97 -------------------------------------------------- Rv3144c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1484|M.marinum_M -------------------------------------------------- MUL_3169|M.ulcerans_Agy99 ATAIGSGNSQVSAEAGGAGGNIATLSSVFGDNNTAVVTAFGASNVPTAAT MAV_1998|M.avium_104 -------------------------------------------------- Mflv_0768|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0077|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0064|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3569|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mb3168c|M.bovis_AF2122/97 -------------------------------------------------- Rv3144c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1484|M.marinum_M -------------------------------------------------- MUL_3169|M.ulcerans_Agy99 VFGSGNGVKVSTFGLENIATLGTVIGDNNTGVVADAGGVGGNIATLANVF MAV_1998|M.avium_104 -------------------------------------------------- Mflv_0768|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0077|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0064|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3569|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mb3168c|M.bovis_AF2122/97 -------------------------------------------------- Rv3144c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1484|M.marinum_M -------------------------------------------------- MUL_3169|M.ulcerans_Agy99 GNDNTAAEATASGVGGNIATLANVFGDGNAVKANVVGFGNVPSAATVIGS MAV_1998|M.avium_104 -------------------------------------------------- Mflv_0768|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0077|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0064|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3569|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mb3168c|M.bovis_AF2122/97 -------------------------------------------------- Rv3144c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1484|M.marinum_M -------------------------------------------------- MUL_3169|M.ulcerans_Agy99 NNTVTTDVFGVENIATLASVYGDGNSGVLAQSGGVGGNIATLATVIGSNN MAV_1998|M.avium_104 -------------------------------------------------- Mflv_0768|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0077|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0064|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3569|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mb3168c|M.bovis_AF2122/97 -------------------------------------------------- Rv3144c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1484|M.marinum_M -------------------------------------------------- MUL_3169|M.ulcerans_Agy99 TATEASAVGIGGNTATLGTALSDGNAVSATANGFGNTATVATAFIGGGNT MAV_1998|M.avium_104 -------------------------------------------------- Mflv_0768|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0077|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0064|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3569|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mb3168c|M.bovis_AF2122/97 -------------------------------------------------- Rv3144c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1484|M.marinum_M -------------------------------------------------- MUL_3169|M.ulcerans_Agy99 ATASASGVGNIASLATAVGADNAVSATASGAGGNIAIAATAIGDGNTEVT MAV_1998|M.avium_104 -------------------------------------------------- Mflv_0768|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0077|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0064|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3569|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mb3168c|M.bovis_AF2122/97 -------------------------------------------------- Rv3144c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1484|M.marinum_M -------------------------------------------------- MUL_3169|M.ulcerans_Agy99 ADAGGLGGNIGVAATAIGGGNTVAASSTGLTIGSVATAVGDGNTGIAARG MAV_1998|M.avium_104 -------------------------------------------------- Mflv_0768|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0077|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0064|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3569|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mb3168c|M.bovis_AF2122/97 -------------------------------------------------- Rv3144c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1484|M.marinum_M -------------------------------------------------- MUL_3169|M.ulcerans_Agy99 HQAGNLGIVSTAIGFGNTDVAAAGFGVANIGNVATVIGSNNQNVFAGGTG MAV_1998|M.avium_104 -------------------------------------------------- Mflv_0768|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0077|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0064|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3569|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mb3168c|M.bovis_AF2122/97 -------------------------------------------------- Rv3144c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1484|M.marinum_M -------------------------------------------------- MUL_3169|M.ulcerans_Agy99 LSNIATVGGDNNTALAGDQSGGLASVNVATVFGSGSGASAFNGFLNLAIG MAV_1998|M.avium_104 -------------------------------------------------- Mflv_0768|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0077|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0064|M.smegmatis_MC2_155 -------------------------------------------------- MAB_0669|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3569|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- Mb3168c|M.bovis_AF2122/97 ----------------------------- Rv3144c|M.tuberculosis_H37Rv ----------------------------- MMAR_1484|M.marinum_M ----------------------------- MUL_3169|M.ulcerans_Agy99 LTDGVMASAGPGNFNVSIHPFFDVQPLFG MAV_1998|M.avium_104 ----------------------------- Mflv_0768|M.gilvum_PYR-GCK ----------------------------- Mvan_0077|M.vanbaalenii_PYR-1 ----------------------------- MSMEG_0064|M.smegmatis_MC2_155 ----------------------------- MAB_0669|M.abscessus_ATCC_1997 ----------------------------- TH_3569|M.thermoresistible__bu ----------------------------- MLBr_01182|M.leprae_Br4923 -----------------------------