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M. marinum M MMAR_1484 (-)

annotation: PPE family protein
coordinates: 1797440 - 1798780
length: 446

VSFFVLPPEINSLRMFIGAGTAPMLEAAAAWQGLAEELSTAAQSFASVTAGLAGQAWQGSAAMAMASAAA
PYAGWLAAAAAQSAGAAGNARAVASMFEAAQAATVLPTSISANRNAFVQLVMSNLFGQNAPAIAAAESIY
EEMWAADVAAMSGYYSGVSAVAAQVVPWQSVLKGLPGLASGLAGGAGAGSGFAGGSGMVGGAAGSPGSQG
GAGAGSDTAGANAGGDASSSVVAGGGAGGAGLVGAGGYASGGGGADSGAMGAPGGAVDGASSGVGGGGGG
MAASAGAATPGMGAMAMPIAGMAAARAAMAAGGGQSGPVNAGPPVRETAPAAPEPEAAAPAPEEAEAPVP
QMAVLPTADPGIAAAAAPGSKPQATRATGTTGIPASPLRSSPAGTESKRSAPTQDQQDGAEQTAAEDTVV
PLRPEAVAGELRSRVQEPSGIQMRGG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_1484--100% (446)PPE family protein
M. marinum MMMAR_4554-3e-7752.29% (306) PPE family protein
M. marinum MMMAR_1469-5e-7648.79% (330) PPE family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3168cPPE521e-12058.00% (450) PPE-family protein
M. gilvum PYR-GCKMflv_0768-4e-2228.39% (391) PPE protein
M. tuberculosis H37RvRv3144cPPE521e-11957.78% (450) PPE family protein
M. leprae Br4923MLBr_01182-3e-2942.95% (156) PPE-family protein
M. abscessus ATCC 19977MAB_0669-1e-2133.74% (163) PPE-family protein
M. avium 104MAV_1998-2e-5236.02% (422) PPE family protein
M. smegmatis MC2 155MSMEG_0064-1e-2427.92% (437) PPE family protein
M. thermoresistible (build 8)TH_3569-6e-2232.80% (186) PUTATIVE PPE protein
M. ulcerans Agy99MUL_3169-6e-6947.84% (324) PPE family protein
M. vanbaalenii PYR-1Mvan_0077-4e-2228.13% (423) PPE protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb3168c|M.bovis_AF2122/97           ---------MSFVVLPPEINSLRMFIGAGTAPMLAAAAAWDGLAEELGTA
Rv3144c|M.tuberculosis_H37Rv        ---------MSFVVLPPEINSLRMFIGAGTAPMLAAAAAWDGLAEELGTA
MMAR_1484|M.marinum_M               ---------MSFFVLPPEINSLRMFIGAGTAPMLEAAAAWQGLAEELSTA
MUL_3169|M.ulcerans_Agy99           ---------MNFSVLPPEINSLRLFSDAGSTSMLEAAAAWGSLADELQVA
MAV_1998|M.avium_104                ---------MDFGALPPEINSGRMYSGPGPASLLAAAAGWESLAAELADG
Mflv_0768|M.gilvum_PYR-GCK          MANIGIPVPPSWVAFPPEINTSRLQAGAGAVPMLQAAAGWEAFAISLETQ
Mvan_0077|M.vanbaalenii_PYR-1       MATIGIPIPPIWGAFPPEINTSRLQAGAGAVPMLQAAAGWEAFAISLETQ
MSMEG_0064|M.smegmatis_MC2_155      ----------MWIALPPEINTARLMVGAGPAPMLQAAAGWEGLAVLLETQ
MAB_0669|M.abscessus_ATCC_1997      ------MTAPIWMAEPPEVHSALLSAGPGPGAVLAAAVQWQEIGNNYANT
TH_3569|M.thermoresistible__bu      -----MMTAPIWMALPPEVHSALLSSGPGPGSLLAAASAWHALSAEYASA
MLBr_01182|M.leprae_Br4923          --------MFDFAALSPETNSTRMYLGPGSSPILTAAAAWVVLAKELTAA
                                               : . .** ::  :  ..*. .:* **  *  :.      

Mb3168c|M.bovis_AF2122/97           AQSFASVTAGLAGQAWQGPAALAMAAAAAPYAGWLTAAAAQSAGAAGQAR
Rv3144c|M.tuberculosis_H37Rv        AQSFASVTAGLAGQAWQGPAALAMAAAAAPYAGWLTAAAAQSAGAAGQAR
MMAR_1484|M.marinum_M               AQSFASVTAGLAGQAWQGSAAMAMASAAAPYAGWLAAAAAQSAGAAGNAR
MUL_3169|M.ulcerans_Agy99           ASSFSSVTAGLASGAWQGPASAAMSAVAAPYASWLSAAAAQAAGTAGRAS
MAV_1998|M.avium_104                AGNYQAVIAGLTNESWLGPASLSMAGAVMPYVSWLTAVAEQCGRAAAQAT
Mflv_0768|M.gilvum_PYR-GCK          ADELASSLASLSQ-NWQGMASERAVTAAMPMVLWLRMLSLQAHKRALQAS
Mvan_0077|M.vanbaalenii_PYR-1       ADELAASLATLSQ-MWQGTASERAVMATMPMVMWLRMLSLQAQKRAAQAS
MSMEG_0064|M.smegmatis_MC2_155      AAELAAALTNLTS-VWTGAASERAVAATMPMITWLQTTAAQAQKRALQAS
MAB_0669|M.abscessus_ATCC_1997      AVELAQVLAGVRAGSWQGPSASEYVAAHLPYLAWLEQAAAESSVIAAQHE
TH_3569|M.thermoresistible__bu      AAELSSVLANVQAGSWEGPSAERYVAAHAPYLAWLTQQSANSAATAGRHE
MLBr_01182|M.leprae_Br4923          AQGLQSAVEALLT-TFEGESAAALAERVTPYEKWLTQNAASAELTATQLT
                                    *         :    : * ::        *   **   : ..   * .  

Mb3168c|M.bovis_AF2122/97           AVASIFEAAQAATVLPAAVAANRDAFVQLVMTNLFGQNAPLIAAAEGVY-
Rv3144c|M.tuberculosis_H37Rv        AVASIFEAAQAATVLPAAVAANRDAFVQLVMTNLFGQNAPLIAAAEGVY-
MMAR_1484|M.marinum_M               AVASMFEAAQAATVLPTSISANRNAFVQLVMSNLFGQNAPAIAAAESIY-
MUL_3169|M.ulcerans_Agy99           AAAAVFEAAQAAIVHPAMVAANRNELVALVISNLFGQNAPAIAATEAVY-
MAV_1998|M.avium_104                AAASAFEAAYAMTVPPPLIAANRARLLALVQSNIFGQNTPAIMATEAEY-
Mflv_0768|M.gilvum_PYR-GCK          AQASSWTVAATGTPQLPEIELNHVTNATLHATNFLGVNGIPIALNEADY-
Mvan_0077|M.vanbaalenii_PYR-1       AQATAWASAATSTPQLPEIETNHITNAVLNATNFLGVNTVPIAVNEADY-
MSMEG_0064|M.smegmatis_MC2_155      AQASSYSLALATTPPLPEIEQNHITHGVLEATNFLGINTVPIALNEMDYF
MAB_0669|M.abscessus_ATCC_1997      TTAAAYNSALAAMPTLAELAANHITHGVLVGTNFFGINTIPIALNEADY-
TH_3569|M.thermoresistible__bu      TAAAAYSTALATMPTMAELTLNKTTHAVLVATNFLGINTIPIALNEADY-
MLBr_01182|M.leprae_Br4923          VAANAYETAFTMTVPPLMVFVNRAQACLLIMSNIFGQNSTAIAEKEAEY-
                                    . *  :  * :       :  *:     *  :*::* *   *   *  * 

Mb3168c|M.bovis_AF2122/97           EEMWAADVAAMSGYYSGASAIAAQVVPWASLLQR----------------
Rv3144c|M.tuberculosis_H37Rv        EEMWAADVAAMSGYYSGASAIAAQVVPWASLLQR----------------
MMAR_1484|M.marinum_M               EEMWAADVAAMSGYYSGVSAVAAQVVPWQSVLKG----------------
MUL_3169|M.ulcerans_Agy99           EQLWAQDVAVMAGYHAGVSAIAQQLAPWQQALALPAADADFSLSIFGLQL
MAV_1998|M.avium_104                SEMWAQDATAMYG-YAANSASASALSPVPSPPQP----------------
Mflv_0768|M.gilvum_PYR-GCK          IRMWNQAAAVMTAYETETVLNTTFEPVAPPKPIA----------------
Mvan_0077|M.vanbaalenii_PYR-1       IRMWNQAAAVMTGYETETILNSTFEPVAPPKPIT----------------
MSMEG_0064|M.smegmatis_MC2_155      VRMWNQAAGAMDVYHAETTVNLLFEPIMPMKPIV----------------
MAB_0669|M.abscessus_ATCC_1997      VRMWVQAAATMSAYQATTEAMTSAIPPTQQPPAI----------------
TH_3569|M.thermoresistible__bu      VRMWIQAATSMSTYQAVAGTAVMSAPASSPAPLL----------------
MLBr_01182|M.leprae_Br4923          TEMWIQDAAAMTSYQASVLEAVGATKAFTAPPLG----------------
                                     .:*   .  *    :                                  

Mb3168c|M.bovis_AF2122/97           -----------FPGLGAG------------------ATGATGGES---VG
Rv3144c|M.tuberculosis_H37Rv        -----------FPGLGAG------------------ATGATGGES---VG
MMAR_1484|M.marinum_M               -----------LPGLASG------------------LAGGAGAGSGFAGG
MUL_3169|M.ulcerans_Agy99           VKTGTANATTTFGGLAIASGANSSADAGVADIAFAFGSGSSASATGGVLN
MAV_1998|M.avium_104                -----------TNPAAAG---------------HLAAAAHAAVQSGSSAH
Mflv_0768|M.gilvum_PYR-GCK          ------------------------------------VPPGSEAAFAGAMS
Mvan_0077|M.vanbaalenii_PYR-1       ------------------------------------VFGSTQAAMATAIG
MSMEG_0064|M.smegmatis_MC2_155      ------------------------------------LPGVGETTAAAALA
MAB_0669|M.abscessus_ATCC_1997      ------------------------------------LSPGGEARSDQSDV
TH_3569|M.thermoresistible__bu      ------------------------------------LAPG---VSEAADA
MLBr_01182|M.leprae_Br4923          --------------------------------------VNEVGLAQEVVE
                                                                                      

Mb3168c|M.bovis_AF2122/97           TGATGGES--VGTGGGE----SVG--------------------------
Rv3144c|M.tuberculosis_H37Rv        TGATGGES--VGTGGGE----SVG--------------------------
MMAR_1484|M.marinum_M               SGMVGGAAGSPGSQGGA----GAGS-------------------------
MUL_3169|M.ulcerans_Agy99           IAGVGGANSSASATGGI----NIGTGALAVGDGNTVNASSIGVANIGTVA
MAV_1998|M.avium_104                TTTAHWMSSVPQTLQGLSTPG-----------------------------
Mflv_0768|M.gilvum_PYR-GCK          GAVPGAGEAVMRN-------------------------------------
Mvan_0077|M.vanbaalenii_PYR-1       SAAPGIASAAARN-------------------------------------
MSMEG_0064|M.smegmatis_MC2_155      QTAPRVAEGVMRN-------------------------------------
MAB_0669|M.abscessus_ATCC_1997      PGSPDQIMKMLQGFQQW---------------------------------
TH_3569|M.thermoresistible__bu      MATTQQIGSQAT--------------------------------------
MLBr_01182|M.leprae_Br4923          EVVEEVVEEVVEA-------------------------------------
                                                                                      

Mb3168c|M.bovis_AF2122/97           --------------------------------------------------
Rv3144c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_1484|M.marinum_M               --------------------------------------------------
MUL_3169|M.ulcerans_Agy99           AAFGNNSVTAIANGVENNATVAAAFGNNNTDVSAIVNGVENTGVVSAVFG
MAV_1998|M.avium_104                --------------------------------------------------
Mflv_0768|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0077|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0064|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3569|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3168c|M.bovis_AF2122/97           --------------------------------------------------
Rv3144c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_1484|M.marinum_M               --------------------------------------------------
MUL_3169|M.ulcerans_Agy99           SDNSGVSANAFGVENNAIVATAAGSGNSNVMANAGGVGANEILVAAALGN
MAV_1998|M.avium_104                --------------------------------------------------
Mflv_0768|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0077|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0064|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3569|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3168c|M.bovis_AF2122/97           -------------------------------------------------T
Rv3144c|M.tuberculosis_H37Rv        -------------------------------------------------T
MMAR_1484|M.marinum_M               ------------------------------------------------DT
MUL_3169|M.ulcerans_Agy99           NNSAIANATGVGGTLGTGAISLIGNNNTLYADATGAGHIGTVASALFGDN
MAV_1998|M.avium_104                ------------------------------------------------ST
Mflv_0768|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0077|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0064|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3569|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3168c|M.bovis_AF2122/97           GGATASG------------GGVG---------------------------
Rv3144c|M.tuberculosis_H37Rv        GGATASG------------GGVG---------------------------
MMAR_1484|M.marinum_M               AGANAGGDASSSVVAGGGAGGAG---------------------------
MUL_3169|M.ulcerans_Agy99           NGVKATSFGLNNIATVATAGGSGNTTVAAEASGAENVAVLATAFGNNNPT
MAV_1998|M.avium_104                PGNGLSP------------TAMG---------------------------
Mflv_0768|M.gilvum_PYR-GCK          -------------------------------------------------A
Mvan_0077|M.vanbaalenii_PYR-1       -------------------------------------------------A
MSMEG_0064|M.smegmatis_MC2_155      -------------------------------------------------A
MAB_0669|M.abscessus_ATCC_1997      -----------------------------------------------FEK
TH_3569|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3168c|M.bovis_AF2122/97           ----YVGGG-VASAGLAAGDP----------------AHGSVGQGNFGGG
Rv3144c|M.tuberculosis_H37Rv        ----YVGSG-VASAGLAAGDP----------------AHGSVGQGNFGGG
MMAR_1484|M.marinum_M               ----LVGAGGYASGGGGADSG----------------AMGAPG-GAVDGA
MUL_3169|M.ulcerans_Agy99           VTANVLGAGNLATAATALGNNNTINANVVGLENIATVATAGGNDNGVGAS
MAV_1998|M.avium_104                -----TGAALGSSGPFSSLSS----------------LTGASGKGATKSA
Mflv_0768|M.gilvum_PYR-GCK          IISKVSSTAKLDTANQIAGRA----------------EGTLRGVVDRAGS
Mvan_0077|M.vanbaalenii_PYR-1       TFTKVSVVGKLDEVNQKAGHA----------------EGLLQQAADSGRS
MSMEG_0064|M.smegmatis_MC2_155      VIEGVSAIATIESVGLAAGHA----------------AAQANFAEQRGQG
MAB_0669|M.abscessus_ATCC_1997      MGFNPATSAVLAVIMLFLYDL----------------LWYPYYASYLLPF
TH_3569|M.thermoresistible__bu      ----AADSGTALNLSDLIANL----------------LQY--YQDYLDQL
MLBr_01182|M.leprae_Br4923          -----EQAISQAALDQAVNEG----------------MEATVVPQVDQQV
                                                                                      

Mb3168c|M.bovis_AF2122/97           DVGAGDVVASSATS------------------------------------
Rv3144c|M.tuberculosis_H37Rv        DVGAGDVVASSATS------------------------------------
MMAR_1484|M.marinum_M               SSGVGGGGGGMAAS------------------------------------
MUL_3169|M.ulcerans_Agy99           GVGVGGNIGNIATAFGNSNSQVSADASGAGGNLGTVATAFGNENNVTASA
MAV_1998|M.avium_104                STGAGAGLASALAAG-----------------------------------
Mflv_0768|M.gilvum_PYR-GCK          HAEKSQGLEQAPQ-------------------------------------
Mvan_0077|M.vanbaalenii_PYR-1       QAEQGQLLQQAPQ-------------------------------------
MSMEG_0064|M.smegmatis_MC2_155      AAQKGENAGQEAGR------------------------------------
MAB_0669|M.abscessus_ATCC_1997      LIPALSGLSGLAAL------------------------------------
TH_3569|M.thermoresistible__bu      FGPIVDFLR-----------------------------------------
MLBr_01182|M.leprae_Br4923          NVDVATPQTAVPDSS-----------------------------------
                                                                                      

Mb3168c|M.bovis_AF2122/97           --------------------------------------------------
Rv3144c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_1484|M.marinum_M               --------------------------------------------------
MUL_3169|M.ulcerans_Agy99           FGAGNIGNVSSALFSNNNTISASSIGVENIGTVATSIGDNNTVSATNGLG
MAV_1998|M.avium_104                --------------------------------------------------
Mflv_0768|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0077|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0064|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3569|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3168c|M.bovis_AF2122/97           -------------------------------------------AHAGVVS
Rv3144c|M.tuberculosis_H37Rv        -------------------------------------------AHAGVVS
MMAR_1484|M.marinum_M               -------------------------------------------AGAATPG
MUL_3169|M.ulcerans_Agy99           LGGNIATVATALGGQNNTVSAETGTGGANIASVSTVLFGENNTASASAVG
MAV_1998|M.avium_104                -------------------------------------------PAADGAA
Mflv_0768|M.gilvum_PYR-GCK          ----------------------------------------------QGMQ
Mvan_0077|M.vanbaalenii_PYR-1       ----------------------------------------------QGMQ
MSMEG_0064|M.smegmatis_MC2_155      -------------------------------------------ESGKNMQ
MAB_0669|M.abscessus_ATCC_1997      -------------------------------------------MHLRPAA
TH_3569|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          -------------------------------------------SAAAPQL
                                                                                      

Mb3168c|M.bovis_AF2122/97           PG---------------------------------------------FIG
Rv3144c|M.tuberculosis_H37Rv        PG---------------------------------------------FIG
MMAR_1484|M.marinum_M               MG---------------------------------------------AMA
MUL_3169|M.ulcerans_Agy99           AGNIANVATVSFCDNNTSNASSFGVENIAAVATSYGDGNTVTATNSLGLG
MAV_1998|M.avium_104                AG----------------------------------------------LA
Mflv_0768|M.gilvum_PYR-GCK          MG--------------------------------------------MQMA
Mvan_0077|M.vanbaalenii_PYR-1       MG--------------------------------------------MQMA
MSMEG_0064|M.smegmatis_MC2_155      QG--------------------------------------------MQMV
MAB_0669|M.abscessus_ATCC_1997      PG--------------------------------------------PVPA
TH_3569|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          WG---------------------------------------------GFA
                                                                                      

Mb3168c|M.bovis_AF2122/97           APLA--LAALG--------QMARGGT------------NSAPGTATESAR
Rv3144c|M.tuberculosis_H37Rv        APLA--LAALG--------QMARGGT------------NSAPGTATESAR
MMAR_1484|M.marinum_M               MPIAGMAAARA--------AMAAGGG------------QSGPVNAGPPVR
MUL_3169|M.ulcerans_Agy99           GNIATVATALGGQDNTVSAQAGAGGANIAQVATVLFGDNNTASASGLGAG
MAV_1998|M.avium_104                EEAAGYGADGAG-------LIADGGGIG-------IDLYGLDLDYQGLAL
Mflv_0768|M.gilvum_PYR-GCK          SQLG---STLGQ------MPQQMMQG-----------VTQPFQQLTQPLQ
Mvan_0077|M.vanbaalenii_PYR-1       SQLG---STLGQ------LPQQMMQG-----------VTQPFQQLTQPLQ
MSMEG_0064|M.smegmatis_MC2_155      MQMG---SQAAQ------APAQLASM-----------FQSGVQTMTQPLQ
MAB_0669|M.abscessus_ATCC_1997      AALSPGDRPIRR------PTQHVEPN-----------LAALPLPTSSVVP
TH_3569|M.thermoresistible__bu      -------DPIGN------LFQLIDDF-----------LTN---PAGALVT
MLBr_01182|M.leprae_Br4923          QHLSPINDTLSMIN----NHAGMANAG--------LSLVNGMGSAMKSLA
                                                                                      

Mb3168c|M.bovis_AF2122/97           APEPAASAP--PEAVVEVPELEVPAMGVLPT--VDPKVAAKAAP------
Rv3144c|M.tuberculosis_H37Rv        APEPAASAP--PEAVVEVPELEVPAMGVLPT--VDPKVAAKAAP------
MMAR_1484|M.marinum_M               ETAPAAPEPEAAAPAPEEAEAPVPQMAVLPT--ADPGIAAAAAP------
MUL_3169|M.ulcerans_Agy99           NIADVATVLFSNNNTSTASALGVENIATIVTSYGDNNNVSATAPGIG---
MAV_1998|M.avium_104                DEAGAGSILGAEAGTGIAGTAGLGSLEPPAG--LGQGASASVGQAGA---
Mflv_0768|M.gilvum_PYR-GCK          QMSSLFGGM--MNGDK-GAQIGMVGATPFSNHPAIGGTGPATGSG-----
Mvan_0077|M.vanbaalenii_PYR-1       QMSSLFGQMGGLGGDR-GAQIGMLGATPFSNHPAIGGSGAATGAG-----
MSMEG_0064|M.smegmatis_MC2_155      QATQMVSQFASMGGSERAMQVGLMGASPFSNHPMLGGSGPSTGAG-----
MAB_0669|M.abscessus_ATCC_1997      SGGSSVPVSTPTAPAHTVSSVPAPSAAISYAIPGLVPPGVSFGPKSTEKS
TH_3569|M.thermoresistible__bu      ----WWPLLFAVAYQVFTNLVGWPTWAMILASPVLIPLAITLG-------
MLBr_01182|M.leprae_Br4923          PTTTKAAESAFKAMGSAVQSTGRGLLGSSSGGHVTAQLGRAASIG-----
                                                                              .       

Mb3168c|M.bovis_AF2122/97           --LSTTRVGQSAG-SGIPESTLRTAQG-------------QQASETSAA-
Rv3144c|M.tuberculosis_H37Rv        --LSTTRVGQSAG-SGIPESTLRTAQG-------------QQASETSAA-
MMAR_1484|M.marinum_M               --GSKPQATRATGTTGIPASPLRSSPAGTESKRSAPTQDQQDGAEQTAA-
MUL_3169|M.ulcerans_Agy99           --ANIATVATALGGQGNTVSAESGGAGANIASVSTVLFGENNTASASAVG
MAV_1998|M.avium_104                --LSTLSVPPSWATTVSTVTPLPSPNSGPVPG--------GWAAAPTAS-
Mflv_0768|M.gilvum_PYR-GCK          -------LVRAASLPGAGGSAPQTPLMSNLVGSGLQPT-SPVAVGAGAG-
Mvan_0077|M.vanbaalenii_PYR-1       -------LVRAASLPGAGGTAARTPLMSNLVGSGLQPTVSAVAVGAGAG-
MSMEG_0064|M.smegmatis_MC2_155      -------LVRAMSLPGAGGTAPRTPLLSNLLG----ISGEMKAAPAGAG-
MAB_0669|M.abscessus_ATCC_1997      SESAVDTVAAVAAARGAVAAQARRRLRGKNKAEAGGRRHEYLEETAGMGA
TH_3569|M.thermoresistible__bu      -----------VAGLVMIADQAQP--------------------------
MLBr_01182|M.leprae_Br4923          ----SLRVPQTWTTASQPVTAATRALSPARVA--------VATESESAP-
                                                                                      

Mb3168c|M.bovis_AF2122/97           ----------------EETAPSLRPEAAAGQLRPR-------VRQD----
Rv3144c|M.tuberculosis_H37Rv        ----------------EETAPSLRPEAAAGQLRPR-------VRKD----
MMAR_1484|M.marinum_M               ----------------EDTVVPLRPEAVAGELRSR-------VQEP----
MUL_3169|M.ulcerans_Agy99           AGNIANVATVLFSDSNTSTVSSFGVENIATVATSYGDFNNVSARTPGIGG
MAV_1998|M.avium_104                ---------------PGPAVSRLPLGGMVGRESEG------PVHRVG---
Mflv_0768|M.gilvum_PYR-GCK          ----------------PGAGVGLAPVGTGGGMGAGG-----PMGMFG---
Mvan_0077|M.vanbaalenii_PYR-1       ----------------AGAGAGLAPVGAGSGMGGGG-----PMGMLG---
MSMEG_0064|M.smegmatis_MC2_155      ----------------SAAAGGLAPVGAGAGGGAGA-----PVAHAG---
MAB_0669|M.abscessus_ATCC_1997      TATAD-------VPAYAATGRGTGPLGFAGTAPAAA-----STHVAA---
TH_3569|M.thermoresistible__bu      -----------------------------PAEEAAP-----EEDVAA---
MLBr_01182|M.leprae_Br4923          ---------------LLGGGLPMAPMVPGGGSGTGG--------------
                                                                                      

Mb3168c|M.bovis_AF2122/97           -------------PKIQMRGG-----------------------------
Rv3144c|M.tuberculosis_H37Rv        -------------PKIQMRGG-----------------------------
MMAR_1484|M.marinum_M               -------------SGIQMRGG-----------------------------
MUL_3169|M.ulcerans_Agy99           NIATFATAFGEGNTNVHAEAGPGGANIATLATVFGDGNAVSVKSIGAGNT
MAV_1998|M.avium_104                -------------QRVSLIPQVIG--------------------------
Mflv_0768|M.gilvum_PYR-GCK          --------------QRGKSGGNKPGLNAPAPLDHDLGEDEDEEW------
Mvan_0077|M.vanbaalenii_PYR-1       --------------QRGKSGGNKPGLNAPAPLEHDLSEDDDDDW------
MSMEG_0064|M.smegmatis_MC2_155      --------------QNSKSGGKKDGLVAPTPLTYDLSEDEDDEW------
MAB_0669|M.abscessus_ATCC_1997      --------------TVRLSSDEARQVIPMLPSTWDADGGDQN--------
TH_3569|M.thermoresistible__bu      --------------PVRAEPQNP------LPLTXXX--------------
MLBr_01182|M.leprae_Br4923          -------------VNTALRLQPRAFVMPRNPAAG----------------
                                                                                      

Mb3168c|M.bovis_AF2122/97           --------------------------------------------------
Rv3144c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_1484|M.marinum_M               --------------------------------------------------
MUL_3169|M.ulcerans_Agy99           ASIATMIGNNNTADINVFGLENVATVATAIGDNNGLTANAPGLGANIATV
MAV_1998|M.avium_104                --------------------------------------------------
Mflv_0768|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0077|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0064|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3569|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3168c|M.bovis_AF2122/97           --------------------------------------------------
Rv3144c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_1484|M.marinum_M               --------------------------------------------------
MUL_3169|M.ulcerans_Agy99           ATAIGSGNSQVSAEAGGAGGNIATLSSVFGDNNTAVVTAFGASNVPTAAT
MAV_1998|M.avium_104                --------------------------------------------------
Mflv_0768|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0077|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0064|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3569|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3168c|M.bovis_AF2122/97           --------------------------------------------------
Rv3144c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_1484|M.marinum_M               --------------------------------------------------
MUL_3169|M.ulcerans_Agy99           VFGSGNGVKVSTFGLENIATLGTVIGDNNTGVVADAGGVGGNIATLANVF
MAV_1998|M.avium_104                --------------------------------------------------
Mflv_0768|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0077|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0064|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3569|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3168c|M.bovis_AF2122/97           --------------------------------------------------
Rv3144c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_1484|M.marinum_M               --------------------------------------------------
MUL_3169|M.ulcerans_Agy99           GNDNTAAEATASGVGGNIATLANVFGDGNAVKANVVGFGNVPSAATVIGS
MAV_1998|M.avium_104                --------------------------------------------------
Mflv_0768|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0077|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0064|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3569|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3168c|M.bovis_AF2122/97           --------------------------------------------------
Rv3144c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_1484|M.marinum_M               --------------------------------------------------
MUL_3169|M.ulcerans_Agy99           NNTVTTDVFGVENIATLASVYGDGNSGVLAQSGGVGGNIATLATVIGSNN
MAV_1998|M.avium_104                --------------------------------------------------
Mflv_0768|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0077|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0064|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3569|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3168c|M.bovis_AF2122/97           --------------------------------------------------
Rv3144c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_1484|M.marinum_M               --------------------------------------------------
MUL_3169|M.ulcerans_Agy99           TATEASAVGIGGNTATLGTALSDGNAVSATANGFGNTATVATAFIGGGNT
MAV_1998|M.avium_104                --------------------------------------------------
Mflv_0768|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0077|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0064|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3569|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3168c|M.bovis_AF2122/97           --------------------------------------------------
Rv3144c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_1484|M.marinum_M               --------------------------------------------------
MUL_3169|M.ulcerans_Agy99           ATASASGVGNIASLATAVGADNAVSATASGAGGNIAIAATAIGDGNTEVT
MAV_1998|M.avium_104                --------------------------------------------------
Mflv_0768|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0077|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0064|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3569|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3168c|M.bovis_AF2122/97           --------------------------------------------------
Rv3144c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_1484|M.marinum_M               --------------------------------------------------
MUL_3169|M.ulcerans_Agy99           ADAGGLGGNIGVAATAIGGGNTVAASSTGLTIGSVATAVGDGNTGIAARG
MAV_1998|M.avium_104                --------------------------------------------------
Mflv_0768|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0077|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0064|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3569|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3168c|M.bovis_AF2122/97           --------------------------------------------------
Rv3144c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_1484|M.marinum_M               --------------------------------------------------
MUL_3169|M.ulcerans_Agy99           HQAGNLGIVSTAIGFGNTDVAAAGFGVANIGNVATVIGSNNQNVFAGGTG
MAV_1998|M.avium_104                --------------------------------------------------
Mflv_0768|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0077|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0064|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3569|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3168c|M.bovis_AF2122/97           --------------------------------------------------
Rv3144c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_1484|M.marinum_M               --------------------------------------------------
MUL_3169|M.ulcerans_Agy99           LSNIATVGGDNNTALAGDQSGGLASVNVATVFGSGSGASAFNGFLNLAIG
MAV_1998|M.avium_104                --------------------------------------------------
Mflv_0768|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0077|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0064|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997      --------------------------------------------------
TH_3569|M.thermoresistible__bu      --------------------------------------------------
MLBr_01182|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3168c|M.bovis_AF2122/97           -----------------------------
Rv3144c|M.tuberculosis_H37Rv        -----------------------------
MMAR_1484|M.marinum_M               -----------------------------
MUL_3169|M.ulcerans_Agy99           LTDGVMASAGPGNFNVSIHPFFDVQPLFG
MAV_1998|M.avium_104                -----------------------------
Mflv_0768|M.gilvum_PYR-GCK          -----------------------------
Mvan_0077|M.vanbaalenii_PYR-1       -----------------------------
MSMEG_0064|M.smegmatis_MC2_155      -----------------------------
MAB_0669|M.abscessus_ATCC_1997      -----------------------------
TH_3569|M.thermoresistible__bu      -----------------------------
MLBr_01182|M.leprae_Br4923          -----------------------------