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NFSIFPPEINSLRMFTGAGSAPMLQAAAAWEGLAGELGSAADSFASVTSGLVGQAWQGPASAAMAAAVAP YTSWLSAAAAQAVGAAGAAKMVASAFEAARAATVLPAAVAANRNALVQMVMSNIFGQNAPAIAAAEAAYE EMWAQDVAAMFGYHSGASAVAAALSPWEQLLQNVPALSPLAAIGNLGAGNLGFGNTGIANLGNGNTGNLN FGGGNIGNFNFGSGNRGGNVNFGNGNNGFFNLGGGNIGSNNFGSGNRGNGNIGFGNYQSTGGANIGGGNS GSGNKGFGNTGNYNIGSGNFGSFNFGDGNRGSNNFGFGNTNSGNVGFGNLGANNVGFGNLGSGNVGFGNT GNNNFGIGLSGNDQVGINFNGLNGGSGNIGLFNSGNNNVGFFNSGDGNWGIGNSGDTNTGIGNSGSFNTG FVNAASLNTGMANSANTCLGVGNSGAGDVGFMNAGHDNVGLGNAGSFNMGFGNAGSGNVGYENAGGANVG FGNSGSDNTGFLNSGSVNTGFLNSGSTNTGAGNSGEVNTGFGIATDSGATNSGFGNTGSGNSGFNNDGND NSGFQNTGTSSEGFGNVGNNQTGFQNTGGTNTGFFNTGTNDVGVGNSANLNIGFWNSTGAGNVGVMNTGT DNSGFIQTGTANSGFANSGTSSSGGLNKGDQQSGFGN*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4554 | - | - | 100% (668) | PPE family protein |
| M. marinum M | MMAR_1139 | - | 0.0 | 58.87% (654) | PPE family protein |
| M. marinum M | MMAR_4319 | - | 0.0 | 54.91% (692) | PPE family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3183c | PPE53 | 0.0 | 55.26% (666) | PPE family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 4e-34 | 28.09% (687) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv3533c | PPE62 | 0.0 | 59.17% (627) | PPE family protein |
| M. leprae Br4923 | MLBr_01182 | - | 1e-30 | 44.17% (163) | PPE-family protein |
| M. abscessus ATCC 19977 | MAB_4284c | - | 1e-26 | 29.79% (470) | hypothetical protein MAB_4284c |
| M. avium 104 | MAV_4704 | - | 5e-51 | 52.79% (197) | PPE family protein |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 8e-33 | 27.26% (576) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3113 | - | 6e-23 | 38.61% (158) | PUTATIVE PPE protein |
| M. ulcerans Agy99 | MUL_0902 | - | 0.0 | 58.41% (654) | PPE family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-31 | 26.63% (676) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3183c|M.bovis_AF2122/97 --------------------------------------------------
MUL_0902|M.ulcerans_Agy99 --------------------------------------------------
Rv3533c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4554|M.marinum_M --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------------MMFLAPPG
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3183c|M.bovis_AF2122/97 --------------------------------------------------
MUL_0902|M.ulcerans_Agy99 --------------------------------------------------
Rv3533c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4554|M.marinum_M --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ---------------------------------------MVTFGGGATPT
Mvan_1264|M.vanbaalenii_PYR-1 GPGPISAAIQLTSTGSEATEP----------------WYVVSFGGSGAPT
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3183c|M.bovis_AF2122/97 --------------------------------------------------
MUL_0902|M.ulcerans_Agy99 --------------------------------------------------
Rv3533c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4554|M.marinum_M --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK PTSLGAA-------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 PNNLAAS-------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3183c|M.bovis_AF2122/97 --------------------------------------------------
MUL_0902|M.ulcerans_Agy99 --------------------------------------------------
Rv3533c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4554|M.marinum_M --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3183c|M.bovis_AF2122/97 ------------------------------------------MN---YSV
MUL_0902|M.ulcerans_Agy99 ------------------------------------------MN---FPM
Rv3533c|M.tuberculosis_H37Rv ------------------------------------------MN---YAV
MMAR_4554|M.marinum_M ------------------------------------------MN---FSI
MAV_4704|M.avium_104 ------------------------------------------MTNPHFAW
Mflv_5091|M.gilvum_PYR-GCK --------------------AVDLSGTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 --------------------LVDLSGTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
MLBr_01182|M.leprae_Br4923 --------------------------------------------MFDFAA
TH_3113|M.thermoresistible__bu ------------------------------------------------MA
MAB_4284c|M.abscessus_ATCC_199 ----------------------------------------MSIIDFILNL
Mb3183c|M.bovis_AF2122/97 LPPEINSLRMFTGAGSAPMLAASVAWDR--------LAAELAVAASSFGS
MUL_0902|M.ulcerans_Agy99 LPPEINSARMFAGAGSGPMLSAAMAWDG--------LAVELGSAAESFGS
Rv3533c|M.tuberculosis_H37Rv LPPELNSLRMFTGAGSAPMLAAAVAWDG--------LAAELGSAASSFGS
MMAR_4554|M.marinum_M FPPEINSLRMFTGAGSAPMLQAAAAWEG--------LAGELGSAADSFAS
MAV_4704|M.avium_104 LPPEVNSALIYSGPGPGPLLAAAAAWDG--------LAEELASSAQSFSS
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
MLBr_01182|M.leprae_Br4923 LSPETNSTRMYLGPGSSPILTAAAAWVV--------LAKELTAAAQGLQS
TH_3113|M.thermoresistible__bu LPPEVHSTLLRTGPGPGALSAAADAWRM--------LSDEYRAAAVELAA
MAB_4284c|M.abscessus_ATCC_199 FRDPVEAASYVADPEAALANAGLSAVSAAQVGAVMPVVAESVASNYGYQS
. . . : . .
Mb3183c|M.bovis_AF2122/97 VTSG---------LAGQSWQGAAA-AMAAAAAPYAGWLAAAAARAAGASA
MUL_0902|M.ulcerans_Agy99 VTSG---------LVGSSWQGAAATAMSAAAAPYVSWLNAAAVRAGEAAL
Rv3533c|M.tuberculosis_H37Rv VTSD---------LASQAWQGPAAAAMAAAAAPYAGWLSAAAARAAGAAA
MMAR_4554|M.marinum_M VTSG---------LVGQAWQGPASAAMAAAVAPYTSWLSAAAAQAVGAAG
MAV_4704|M.avium_104 VTSD---------LASGSWQGASSAAMMTVANQYVSWLSAAAAQAEEVSH
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
MLBr_01182|M.leprae_Br4923 AVEA----------LLTTFEGESAAALAERVTPYEKWLTQNAASAELTAT
TH_3113|M.thermoresistible__bu VVSQ---------TCATAWEGVGADAYAAAHGPYLFWLTDTAAAAAAAGA
MAB_4284c|M.abscessus_ATCC_199 QWVN----------TGNPIHDLSGNLQNYYAAQPDGPSILSPSLLSPRDN
. .
Mb3183c|M.bovis_AF2122/97 QAKAVASAFEAARAATVHPMLVAANRNAFVQLVLSN-------------L
MUL_0902|M.ulcerans_Agy99 QAKEVVSAFEAARAAMIHPLAVAANRNALVQLVLTN-------------L
Rv3533c|M.tuberculosis_H37Rv QAKAVASAFEAARAATVHPLLVAANRNAFAQLVMSN-------------W
MMAR_4554|M.marinum_M AAKMVASAFEAARAATVLPAAVAANRNALVQMVMSN-------------I
MAV_4704|M.avium_104 QASAIATAFEVALAATVQPAVVAANRALVQALAATN-------------W
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
MLBr_01182|M.leprae_Br4923 QLTVAANAYETAFTMTVPPLMVFVNRAQACLLIMSN-------------I
TH_3113|M.thermoresistible__bu QLEAAAAAHASALAAMPTMAELTANRTTHAALVATN-------------F
MAB_4284c|M.abscessus_ATCC_199 DFLSHNDTDFASHNPIASGNQVMSPSGNVDSFNRGP-------------L
Mb3183c|M.bovis_AF2122/97 FGQNAPAIAAAEAMYEQMWAADVAAMVGYHGGASAAAAQLSSWS------
MUL_0902|M.ulcerans_Agy99 FGQNAPAIAAAEGSYEQMWAADVAAMLGYHGGASAAASGLASWQ------
Rv3533c|M.tuberculosis_H37Rv FGLNAPLIAAVEGAYEQMWAADVAAMVGYHSGASAAAEQLVPFQ------
MMAR_4554|M.marinum_M FGQNAPAIAAAEAAYEEMWAQDVAAMFGYHSGASAVAAALSPWE------
MAV_4704|M.avium_104 LGQNTPAIADIEAAYEQMWASDVAAMFGYHADASAAVAKLPPWN------
Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----AVGAAG------
Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----AIGTAG------
MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH
MLBr_01182|M.leprae_Br4923 FGQNSTAIAEKEAEYTEMWIQDAAAMTSYQASVLEAVGATKAFT------
TH_3113|M.thermoresistible__bu FGVNTIPIAVNEADYARMWIQAATTMATYEAVASAAVSATPRTVAP----
MAB_4284c|M.abscessus_ATCC_199 LDLSFGDLQFGNRDTTAIGDGAVAVGGSNSGPIASGQGSTAVNG------
.. . .
Mb3183c|M.bovis_AF2122/97 --------IGLQQALPAAPSALAAAIGLG-----NIGVGNLGGGNTGEYN
MUL_0902|M.ulcerans_Agy99 --------QALQG-LAGPAASVILGLSIG-----NTGVGNLSIGNIGVFN
Rv3533c|M.tuberculosis_H37Rv --------QALQQ---------LPNLGIG-----NIGNANLGGGNTGDLN
MMAR_4554|M.marinum_M --------QLLQNVPALSPLAAIGNLGAGNLGFGNTGIANLGNGNTGNLN
MAV_4704|M.avium_104 --------EVLQN-------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -AAGTVGTAGATGGTGTGANGGAGGVG-----GVGGTGAAGAAGGAGGLG
Mvan_1264|M.vanbaalenii_PYR-1 -VAGAAGTAGATGGTGVGGNGGAGQAG-----GIGGTGAAGAAGQAGTAG
MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS
MLBr_01182|M.leprae_Br4923 ----------------------APPLGVN-----EVGLAQEVVEEVVEEV
TH_3113|M.thermoresistible__bu ----------------------PPILGAG------TGESATAAITGAHVT
MAB_4284c|M.abscessus_ATCC_199 --------DVRDSNIINADHGSNVGVDQS---QTRVGGDYTNVSGHGSAD
Mb3183c|M.bovis_AF2122/97 LGSGNSGNANVGS-------------------GNSG-NANVGSGNDGATN
MUL_0902|M.ulcerans_Agy99 LGGGNAGNLNLGG-------------------GNTG-NANLGSGNNGFFN
Rv3533c|M.tuberculosis_H37Rv TGNGNIGNTNLGS-------------------GNRG-DANLGSGNIGNSN
MMAR_4554|M.marinum_M FGGGNIGNFNFGS-------------------GNRGGNVNFGNGNNGFFN
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ETGTTGGAGGVG--------------------GQGTAGGTGGVGGIGGAG
Mvan_1264|M.vanbaalenii_PYR-1 ETGVTGGVGGIG--------------------GQGTEGGTGGVGGVGGVG
MSMEG_0868|M.smegmatis_MC2_155 TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIY
MLBr_01182|M.leprae_Br4923 VEEVVEAEQAISQ-------------------------------------
TH_3113|M.thermoresistible__bu AELRAAESRTLLD-------------------------------------
MAB_4284c|M.abscessus_ATCC_199 IDKSVTVVDDHSQ--------------------RNTTNINDSFNTDRSTN
Mb3183c|M.bovis_AF2122/97 --------------------------------------------------
MUL_0902|M.ulcerans_Agy99 --------------------------------------------------
Rv3533c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4554|M.marinum_M --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------STGAVGG-------VGGKG----IQGGQG-----------
Mvan_1264|M.vanbaalenii_PYR-1 ----------ATGGAGG-------VGGKG----IQGGQG-----------
MSMEG_0868|M.smegmatis_MC2_155 SGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTA
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3183c|M.bovis_AF2122/97 --LGSGNIGNTNLGSGNVGNVNL---------------------GSGNR-
MUL_0902|M.ulcerans_Agy99 --LGSGNTGNTNFGNGNRGNLNW---------------------GSGNLG
Rv3533c|M.tuberculosis_H37Rv --VGGGNVGNGNFGSGNGRAGLP---------------------GSGNVG
MMAR_4554|M.marinum_M --LGGGNIGSNNFGSGNRGNGNIGFGNYQST--------GGANIGGGNSG
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --LQGGKGGDGGAGGKGGDADSMGS------------------AGATGGK
Mvan_1264|M.vanbaalenii_PYR-1 --LQGGQGGDGGTGGTGGDATSMGE------------------AGATGGK
MSMEG_0868|M.smegmatis_MC2_155 KAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAV
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --IGSGNTTNTEIGSHNQANIGTSTS-----------------AGGSAAV
Mb3183c|M.bovis_AF2122/97 ----GFGN--------------------LGNGNFGSG-------------
MUL_0902|M.ulcerans_Agy99 NANVGFGNF-------------------LGQGNFGFGNR-----------
Rv3533c|M.tuberculosis_H37Rv NGNLGNSN--------------------LGSGNTGNS-------------
MMAR_4554|M.marinum_M SGNKGFGN--------------------TGNYNIGSGN------------
MAV_4704|M.avium_104 ---LGFSN------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GGNGGNGGRGGLFG---------------KGGNAGNGAD-----------
Mvan_1264|M.vanbaalenii_PYR-1 GGNGGNGGRGSLFG---------------RGGNAGNGGN-----------
MSMEG_0868|M.smegmatis_MC2_155 GGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGP
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GGNAGLAG------------------------NAGLAGN-----------
Mb3183c|M.bovis_AF2122/97 ----------------NLGSGNTGSTNFGGGNLGS---------------
MUL_0902|M.ulcerans_Agy99 ------------VGDANLGSGNLGNANFGNGNLGD---------------
Rv3533c|M.tuberculosis_H37Rv ----------------NVGFGNTGNNNVGTGNAGS---------------
MMAR_4554|M.marinum_M ------------FGSFNFGDGNRGSNNFGFGNTNS---------------
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -----------GGTGGAGGAGGTGG-TGGAGGTGG---------------
Mvan_1264|M.vanbaalenii_PYR-1 -----------GGTGGNGGNGGTGG-TGGNGGTGG---------------
MSMEG_0868|M.smegmatis_MC2_155 AGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQ
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------------AGLAGNAGLAGNAGLAGN---------------
Mb3183c|M.bovis_AF2122/97 -------FNLGSGNIGSSNIGFGNNGDNNLGLGNNGNNNIGFGLTGDNLV
MUL_0902|M.ulcerans_Agy99 -------TNLGSGNNGFSNVGFGNLGSNNLGFGNNGDNNIGFGLTGNNQV
Rv3533c|M.tuberculosis_H37Rv -------GNIGAGNTGSSNWGFGNNGIGNIGFGNTGNGNIGFGLTGNNQV
MMAR_4554|M.marinum_M -------GNVGFGNLGANNVGFGNLGSGNVGFGNTGNNNFGIGLSGNDQV
MAV_4704|M.avium_104 ----------------ASTAVTRPAGSGAVARGYTSR-------------
Mflv_5091|M.gilvum_PYR-GCK --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKG
Mvan_1264|M.vanbaalenii_PYR-1 --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKG
MSMEG_0868|M.smegmatis_MC2_155 TDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGRG
MLBr_01182|M.leprae_Br4923 ---------------AALDQAVNEGMEATVVPQVDQQVNVDVATPQTAVP
TH_3113|M.thermoresistible__bu --------EINELIDRLFAPLFPPGFADALPDGLLGTLLAPLLPGATGDG
MAB_4284c|M.abscessus_ATCC_199 ------AGLAGNAGLAGNAGLAGNAGLAGN-AGLAGNAGLAGNAGLAGNA
Mb3183c|M.bovis_AF2122/97 GIG--ALNSGIGNLGFGNSGNNNIGFFNSGN------------NNVGFFN
MUL_0902|M.ulcerans_Agy99 GINFAGLNGGIGNIDLGNSGDNNVGFFNSGS------------NNVGFFN
Rv3533c|M.tuberculosis_H37Rv GIG--GLNSGSGNIGLFNSGTNNVGFFNSGN------------GNLGIGN
MMAR_4554|M.marinum_M GINFNGLNGGSGNIGLFNSGNNNVGFFNSGD------------GNWGIGN
MAV_4704|M.avium_104 ----------------------IAGFLAPRA------------PQ-----
Mflv_5091|M.gilvum_PYR-GCK GTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGGTGGTGG
MSMEG_0868|M.smegmatis_MC2_155 GDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNGG
MLBr_01182|M.leprae_Br4923 DSSSAAAPQLWGGFAQHLSPINDTLS--MIN------------NHAGMAN
TH_3113|M.thermoresistible__bu PPMATIMSFLLMGLSNPAYLFPVLVYLLFTG-----------VVHTTVAV
MAB_4284c|M.abscessus_ATCC_199 GLAGNAGLAGNAGLAGNAGLAGNAGLAGNAG----------LAGNAGLAG
Mb3183c|M.bovis_AF2122/97 SG-----------NNNFGFGNAGD--------INTGFGNA----------
MUL_0902|M.ulcerans_Agy99 SG-----------DRNFGFANSGD--------TNTGFWNA----------
Rv3533c|M.tuberculosis_H37Rv SS-----------DANVGIGNSGATVGPFVAGHNTGFGNS----------
MMAR_4554|M.marinum_M SG-----------DTNTGIGNSGS--------FNTGFVNA----------
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK AG-----------DGTGGTGGTGG----TGGQGGQGGQGG----------
Mvan_1264|M.vanbaalenii_PYR-1 AG-----------DGLGGTGGTGG----TGGFGGQGGQGG----------
MSMEG_0868|M.smegmatis_MC2_155 AGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVIG
MLBr_01182|M.leprae_Br4923 AG----------LSLVNGMGSAMK--------------------------
TH_3113|M.thermoresistible__bu SG---------MLAQLVPLMPALLP-------------------------
MAB_4284c|M.abscessus_ATCC_199 NAG---------LAGNAGLAGNAAVAGNAAVAGNAAVAGNAAVG------
Mb3183c|M.bovis_AF2122/97 ------------------------------------------------GD
MUL_0902|M.ulcerans_Agy99 ------------------------------------------------GR
Rv3533c|M.tuberculosis_H37Rv ------------------------------------------------GS
MMAR_4554|M.marinum_M ------------------------------------------------AS
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -------TGGTGGQGG-LGGGGGTG-----------------------GQ
Mvan_1264|M.vanbaalenii_PYR-1 -------TGGTGGQGG-LGGVGGTG-----------------------GT
MSMEG_0868|M.smegmatis_MC2_155 SNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATDGH
MLBr_01182|M.leprae_Br4923 ------------------------------------------------SL
TH_3113|M.thermoresistible__bu -------------------------------------------------V
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------------------GV
Mb3183c|M.bovis_AF2122/97 TNTGFGNAGFFNMGIGNAGN----------EDMGVGNGGSFNVGVGNAGN
MUL_0902|M.ulcerans_Agy99 VNTGFGNGGNFNLGFGNGGA----------ANVGVGNGGGGNLGFGNSGT
Rv3533c|M.tuberculosis_H37Rv LNTGMGNAGGVNTGFGNGGA----------INLGFGNSGQLNAGSFNAGS
MMAR_4554|M.marinum_M LNTGMANSANTCLGVGNSGAGDVGFMNAGHDNVGLGNAGSFNMGFGNAGS
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGS
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGV
MSMEG_0868|M.smegmatis_MC2_155 GGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGGD
MLBr_01182|M.leprae_Br4923 APTTTKAAESAFKAMG--------------SAVQSTGRGLLGSSSGGHVT
TH_3113|M.thermoresistible__bu AVAALGGLAGVWAGLSGLAGLAG------LTAVPAADGGASAAPVPAGGP
MAB_4284c|M.abscessus_ATCC_199 LNTGVSGAIGGSSHVGGAINESLGGSGSVGGSTAVGGGAHTGVGGGVSTG
Mb3183c|M.bovis_AF2122/97 QSVGFGNAG----------TLNVGFANAGSINTG------FANSGSINTG
MUL_0902|M.ulcerans_Agy99 ENTGSFNSGGDNG----RNGGNTGSFNSGYVNTG------FFNSGSTNTG
Rv3533c|M.tuberculosis_H37Rv INTGNFNSG----------QGNTGDFNAGVRNTG------WSNSGLTNTG
MMAR_4554|M.marinum_M GNVGYENAGGANVGFGNSGSDNTGFLNSGSVNTG------FLNSGSTNTG
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGSAGKA
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGSAGTA
MSMEG_0868|M.smegmatis_MC2_155 GVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGSTL
MLBr_01182|M.leprae_Br4923 AQLGRAASIGSLRVPQTWTTASQPVTAATRALSP--------ARVAVATE
TH_3113|M.thermoresistible__bu SLPSGSSAPPAPTGSAAPTTGTAPGGAGSPPPAG----------HSVPPA
MAB_4284c|M.abscessus_ATCC_199 VGVGSHVGGGISESLGGSGSVGGSTAVGGGAHTG--------VGGGVSTG
Mb3183c|M.bovis_AF2122/97 GFDSGDRNTGFGSSVDQSVSSSGFG-------------NTGMNSSGFFNT
MUL_0902|M.ulcerans_Agy99 LFNAGSVNTGIGSPDTQPGSISGFG-------------NTGAGVSGFNNS
Rv3533c|M.tuberculosis_H37Rv AFNAGSLNTGFGAVGTGSGPNSGFG-------------NAGTNNSGFFNT
MMAR_4554|M.marinum_M AGNSGEVNTGFGIATDSGATNSGFG-------------NTGSGNSGFNND
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAGKAGATG
Mvan_1264|M.vanbaalenii_PYR-1 GVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGASGAQGSAG
MSMEG_0868|M.smegmatis_MC2_155 GGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGDGG
MLBr_01182|M.leprae_Br4923 SESAPLLGGGLPMAPMVPGGGSGTG---------------GVNTALRLQP
TH_3113|M.thermoresistible__bu PHSAPPVGTSGPPYLIAAQPAPGVARR-----------SAGARRAASIVE
MAB_4284c|M.abscessus_ATCC_199 VGVGSHVGGGISESLGGSGSVGGST------------AVGGGAHTGVGGG
Mb3183c|M.bovis_AF2122/97 GNVSAGYGNNGD----------VQSGINNTNSGGFNVGFYNSGAGTVGIA
MUL_0902|M.ulcerans_Agy99 GDATSGFMNVATTF-------GFASGIN--NVGDYQVGLFNTGFGNAGIA
Rv3533c|M.tuberculosis_H37Rv GVGSSGFQNGGS----------NNSGLQN------AVGTVIA----AGFG
MMAR_4554|M.marinum_M GNDNSGFQNTGTSSEGFGNVGNNQTGFQN--TGGTNTGFFNTGTNDVGVG
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK AAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKA
Mvan_1264|M.vanbaalenii_PYR-1 SAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKA
MSMEG_0868|M.smegmatis_MC2_155 AATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADGWV
MLBr_01182|M.leprae_Br4923 RAFVMPRNPAAG--------------------------------------
TH_3113|M.thermoresistible__bu PAGSAAAAAAARESAPIRRRRGQKDGLHGHRHEHQQPASMSAATAPSAAG
MAB_4284c|M.abscessus_ATCC_199 VNTGVGVGSHVGGGISESLGGSGSVGGSTAVGGGAHTSAINDALGGSGSV
Mb3183c|M.bovis_AF2122/97 N-------------------------------------------------
MUL_0902|M.ulcerans_Agy99 N-------------------------------------------------
Rv3533c|M.tuberculosis_H37Rv N-------------------------------------------------
MMAR_4554|M.marinum_M NSANLNIGFW----------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG-------
Mvan_1264|M.vanbaalenii_PYR-1 GATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG-------
MSMEG_0868|M.smegmatis_MC2_155 QAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWKS
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu IR------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GGSTAVG-------------------------------------------
Mb3183c|M.bovis_AF2122/97 -----------SGLQTTGIANS-------------------GTLNTGVAN
MUL_0902|M.ulcerans_Agy99 -----------SGNATFGIANS-------------------GALSSGISN
Rv3533c|M.tuberculosis_H37Rv -----------TGAQTVGIANS-------------------GVLNSGFFN
MMAR_4554|M.marinum_M ---------NSTGAGNVGVMNTG---------TDNSGFIQTGTANSGFAN
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGGSGAGGAG-
Mvan_1264|M.vanbaalenii_PYR-1 ----AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGGSGTGGAG-
MSMEG_0868|M.smegmatis_MC2_155 GGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGN
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu ---------VLGGAGRISRTRG-------------------SVPHAEITP
MAB_4284c|M.abscessus_ATCC_199 -----------GGAHTSAINESMNSSINASHSSSMNESFGSSMGSHGAAG
Mb3183c|M.bovis_AF2122/97 TGDHSSGGFNQGSDQSGFFGQP-----
MUL_0902|M.ulcerans_Agy99 SGTNSSGGFNTGDDQSGFFN-------
Rv3533c|M.tuberculosis_H37Rv SGVHNSGGFNSENQRSGFGN-------
MMAR_4554|M.marinum_M SGTSSSGGLNKGDQQSGFGN-------
MAV_4704|M.avium_104 ---------------------------
Mflv_5091|M.gilvum_PYR-GCK -GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 -GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 GGNGGNGGNGGADGTPGTAGTTGANNP
MLBr_01182|M.leprae_Br4923 ---------------------------
TH_3113|M.thermoresistible__bu GDPTEPSSPTDRAHRPAEPN-------
MAB_4284c|M.abscessus_ATCC_199 TGFEAQGHAQGHASETAHTTLPGAEHH