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RPGGAARKSWSEIGNYGQVGRPNRQAQRREEILDAAIALIERHDLATLRIADVAAELGLTPNAVRYYFKE MDQLLSELAQRSDTRFYDDRLAVVERIDDPCAQLALTIGAGLPTGPEDAEWRAIWRAVLAAGFELDQRRD VQHIYHRQVGLYTDILDGGARAGAFELRSPAHDVAMTLMAMEDYLGYRIVARDPDLDRETALRLMRGYAE IATGATLPVTA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1506 | - | - | 100% (222) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5332 | - | 2e-30 | 39.59% (197) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_0663 | - | 7e-09 | 27.98% (193) | TetR-family protein transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_4096 | - | 2e-06 | 29.91% (107) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4765 | - | 4e-05 | 35.00% (100) | putative regulatory protein TetR |
| M. marinum M | MMAR_0992 | - | 3e-07 | 35.16% (91) | transcriptional regulatory protein |
| M. avium 104 | MAV_2960 | - | 9e-07 | 39.58% (96) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_4019 | - | 3e-07 | 36.63% (101) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_0743 | - | 4e-07 | 35.16% (91) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_0372 | - | 2e-05 | 32.26% (93) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0992|M.marinum_M ------------MIG---ETTSPTQRSGVRDEMLHAAVALLDAHGPDALQ
MUL_0743|M.ulcerans_Agy99 ------------MIG---ETTSPTQRSGVRDEMLHAAVALLDAHGPDALQ
MAV_2960|M.avium_104 ------------MRSHGWAGNTPASDAEAIERILDAADRIIAERG-SALR
Mvan_0372|M.vanbaalenii_PYR-1 ------------MRSRGWSGRWPASDEEAINRILDAADDIVAEHG-AAMR
MAB_4765|M.abscessus_ATCC_1997 -----------MARRRGWDGQPPSSDEEAAERIVAAAVKLIGETG-SAVS
Mflv_4096|M.gilvum_PYR-GCK ------------MGRKGWAGAPPRDDEEARTRIVEAALTCIERHGPSQTS
MSMEG_1506|M.smegmatis_MC2_155 MRPGGAARKSWSEIGNYGQVGRPNRQAQRREEILDAAIALIERHDLATLR
TH_4019|M.thermoresistible__bu -----------MVDAGETTDGRRARGQRRRAEIIDATLAVVERDGAAGVT
.:: *: : .
MMAR_0992|M.marinum_M TRKVAGAAGTSTMAVYTHFGGMPELIAEVAEEGLRQFDTALAVPPS--DD
MUL_0743|M.ulcerans_Agy99 TRKVAGATGTSTMAVYTHFGGMPELIAEVADEGLRQFDTALAVPPS--DD
MAV_2960|M.avium_104 IADVARALGVTRQTVYRYFPGTQALLVASAMRSADGFLDRMAAHLDGVTD
Mvan_0372|M.vanbaalenii_PYR-1 LTDVARALGVTRQTVYRYFPGPEAIVVACAMRAADGFIDQLAAHVRGLTD
MAB_4765|M.abscessus_ATCC_1997 LADVAAELGVIRQTVYRYFPTADALMHAASLASVDGFLDRLTHVVRGITD
Mflv_4096|M.gilvum_PYR-GCK LSDVADTLGITRRTVYRYFATTEDLFTAAAEVALGGFVRRIETITADIDD
MSMEG_1506|M.smegmatis_MC2_155 IADVAAELGLTPNAVRYYFKEMDQLLSELAQRSDTRFYDDRLAVVERIDD
TH_4019|M.thermoresistible__bu HRAVAAEAGIPASLTAYYFATLDDLLVAALSSVADGYTERIREIIERPGD
** * . :* :. : *
MMAR_0992|M.marinum_M PVADLVATGAAYRRYAIERPHMYRLMFGSTSAHGINAPTQNVLTLTISQI
MUL_0743|M.ulcerans_Agy99 PVADLVATGAAYRRYAIERPHMYRLMFGSTSAHGINAPAQNVLTLTISQI
MAV_2960|M.avium_104 PVVAITEG-MAFAVEELASDHQVEFVLNQRHRGGQKVSIISDTALAFGRS
Mvan_0372|M.vanbaalenii_PYR-1 PVAAMVES-VSYSVERLAGDHQFENLLTSRRRGNVTTSLTSETAMTFARS
MAB_4765|M.abscessus_ATCC_1997 PAEALTEG-VLYTLEEVTRTPHLGIMMSEPYAHSHTSDMTSDEAQAFGLR
Mflv_4096|M.gilvum_PYR-GCK VAGQLVEV-VAFIVERLPEEPLLTLLLENDRTNQFSRRMLSAPVIDRCRV
MSMEG_1506|M.smegmatis_MC2_155 PCAQLALT-IGAGLPTGPEDAEWRAIWRAVLAAGFELDQRRDVQHIYHRQ
TH_4019|M.thermoresistible__bu RLRGLAELIVESAGPGRERALAERELS--------TLAARRPALQPVARR
:. :
MMAR_0992|M.marinum_M EQRHPSFAHVVRGVR-RSMLAGRITVNGGADRNRASAPDGLATDVPDAEI
MUL_0743|M.ulcerans_Agy99 EQRHPSFAHVVRGVR-RSMLAGRITVNGGDDRNRAAAPDGLATDVLDAEI
MAV_2960|M.avium_104 MLHRYDIDWESYGFD-EAGLEELNEFSLRVLHSFLTDPG-----------
Mvan_0372|M.vanbaalenii_PYR-1 ILQRFDIDWKQHGFD-ETALDELAELSLRTMHSLLVDPG-----------
MAB_4765|M.abscessus_ATCC_1997 MLDRFDVDWVQYGYD-DAAKRELVEFALRIMLSFFVSPN-----------
Mflv_4096|M.gilvum_PYR-GCK ILRHSRIDWEGLGYVSDADIDELIEFLLRMIQSMVIAPP-----------
MSMEG_1506|M.smegmatis_MC2_155 VGLYTDILDGGARAG-AFELRSPAHDVAMTLMAMEDYLG-----------
TH_4019|M.thermoresistible__bu WRDNVAELASTLTDD-PQAIAALVAASDGLCTAILIDNA-----------
MMAR_0992|M.marinum_M VATAAQFWALIHGFVMLELAGFFGDEGAAIEPVLASMTTNLLVALGDSPE
MUL_0743|M.ulcerans_Agy99 VATAAQFWALIHGFVMLELAGFFGDEGAAIEPVLASMTTNLLVALGDSPE
MAV_2960|M.avium_104 --RPPRTGADLRRYLTRWIG-----------PAIAYPQLLRAMDALGAAE
Mvan_0372|M.vanbaalenii_PYR-1 --EPPRDGVALRRFVARWLG-----------PAILYPRLARAVDVIS---
MAB_4765|M.abscessus_ATCC_1997 --EATRSRDELRGFLKRWLG-----------GAVLAQGR-----------
Mflv_4096|M.gilvum_PYR-GCK --EPPRDSAALRSYLHRWVG-----------PALTAGR------------
MSMEG_1506|M.smegmatis_MC2_155 YRIVARDPDLDRETALRLMRG---------YAEIATGATLPVTA------
TH_4019|M.thermoresistible__bu ----PADVDFAHGVLRRALG-------------VPAEHQP----------
. : : :
MMAR_0992|M.marinum_M LAKRSQRLATGAG
MUL_0743|M.ulcerans_Agy99 LAKRSQRLTTGAG
MAV_2960|M.avium_104 PQQRPRRRASKAS
Mvan_0372|M.vanbaalenii_PYR-1 ----PRR------
MAB_4765|M.abscessus_ATCC_1997 -------------
Mflv_4096|M.gilvum_PYR-GCK -------------
MSMEG_1506|M.smegmatis_MC2_155 -------------
TH_4019|M.thermoresistible__bu -------------