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VRILISGASISGPVLAYWLSRYGFDVTVVERAPQLRKAGGHAVDLFRPSMEISAKMGVLSKIEALATGTE TLTWYREGAQRPVRVNLAKIFSATSDHHVEIMRDDLSEIYYEASRNDAEYLFGDSITAISPDGRVSFEHA APRCFDIVVGADGLHSNVRRLVFGEDAGHTQFLGGYLAVVSVPKGLAHDGEMVGHVGPGRMAAVYTAAPL DDARLLFLFRTQEELQYHYRDVLRQKELLREAIAGMHPQVDLWLEELDRTPAFYFDSITQLQLDTWSRGR VTLVGDAGYCPGPAVGGSTSLSVLGAYILAGELAQAGGDYARAFAAYEREMADPVSRSRAFASGVAVSLI PRSKAGVWALTHGAQLVSMLPGGLTKAVAKLNTKGVRLYDSMRFKEYAPPRPG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4675 | - | - | 100% (403) | membrane-associated oxidoreductase |
| M. marinum M | MMAR_4180 | - | 3e-63 | 41.40% (343) | oxidoreductase |
| M. marinum M | MMAR_2185 | - | 3e-51 | 37.28% (338) | oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0590c | - | 2e-49 | 34.97% (346) | hypothetical protein Mb0590c |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv1260 | - | 2e-65 | 41.71% (350) | hypothetical protein Rv1260 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2678 | - | 1e-119 | 53.62% (401) | hypothetical protein MAB_2678 |
| M. avium 104 | MAV_0984 | - | 1e-167 | 72.61% (398) | hypothetical protein MAV_0984 |
| M. smegmatis MC2 155 | MSMEG_5719 | - | 1e-143 | 63.48% (397) | oxidoreductase |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_0294 | - | 0.0 | 95.53% (403) | membrane-associated oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_5278 | - | 1e-17 | 25.00% (352) | monooxygenase, FAD-binding |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4675|M.marinum_M MR-ILISGASISGPVLAYWLSRYGFDVTVVERAPQLRKAGGHAVDLFRPS
MUL_0294|M.ulcerans_Agy99 MR-ILLSGASISGSVLAFWLSRYGFDVTVVERAPQLRKAGGHAVDLFRPS
MAV_0984|M.avium_104 MR-ILISGASIAGPVLAYWLTRYGFEVTVVERAPTLRKTGGHAVDLFRPA
MSMEG_5719|M.smegmatis_MC2_155 MK-VLISGASIAGPVLAYWLSRHGFEVTVVERSPVLRKTGGHAVDLFRPA
MAB_2678|M.abscessus_ATCC_1997 MR-VLISGASIAGPVLAFWLAHYGFEVTVIERSPAPRKSGGHAVDLFKPA
Rv1260|M.tuberculosis_H37Rv MKTVVVSGASVAGTAAAYWLGRHGYSVTMVERHPGLR-PGGQAIDVRGPA
Mb0590c|M.bovis_AF2122/97 MK-VAISGAGVAGAALAHWLQRTGHTPTVIERAPKFR-TGGYMIDFWGVG
Mvan_5278|M.vanbaalenii_PYR-1 MK-VVIVGAGMGGMSAAIALRQIGIDTVVYERVTENK-PVGAAISVWSNG
*: : : **.:.* * * : * .: ** . : . * :.. .
MMAR_4675|M.marinum_M MEISAKMGVLSKIEALATGTETLTWY-REGAQRPVRVNLAKIFSATSDHH
MUL_0294|M.ulcerans_Agy99 MEISAKMGVLSKIEALATGTEILTWY-REGARRPVRVNLAKIFGATSDQH
MAV_0984|M.avium_104 MEISAKMGVLPRIEDLATGTTRLTLY-REGRPQPSRIDLTKIYAASSDRH
MSMEG_5719|M.smegmatis_MC2_155 MEISERMGVLPEIEAHATGTTSMVVH-RPGTSRPARLDYLKVVGVISDRH
MAB_2678|M.abscessus_ATCC_1997 MDIIEMMGILDHVEAQSAGTEVLSIH-REGK-RLIDLPEVLIFSAVSERH
Rv1260|M.tuberculosis_H37Rv LDVLERMGLLAAAQEHKTRIRGASFVDRDGNELFRDTESTPTGGPVNSPD
Mb0590c|M.bovis_AF2122/97 YQVAKRMGITDQIAAAGYHMEHVRSVGPTGK-VKADLGVDVFRRMVGDDF
Mvan_5278|M.vanbaalenii_PYR-1 VKCLNYLGLQEETAELGGKVETMSYVDGHTGDTMCRFSMHPLIEQVGQRP
. :*: ..
MMAR_4675|M.marinum_M VEIMRDDLSEIYYEAS-RNDAEYLFGDSITAISPDGR---VSFEHAAPRC
MUL_0294|M.ulcerans_Agy99 VEIMRDDLSEIYYEAS-RHDTEYLFGDSITAISPDGR---VSFEQAAPRC
MAV_0984|M.avium_104 VEIMRDDLSEVYYDAA-RDDVEYLFGDSITAIEPDGT---VTFEHCAPRT
MSMEG_5719|M.smegmatis_MC2_155 IEIMRDDLSEIYFRAG-RDDVEYLFGDTITSISPDGD---VTFEHHPPRR
MAB_2678|M.abscessus_ATCC_1997 VEIMRDDLSEILYGAS-APSAEYIFGDSITALTDDGAGVRVAFDRASDRR
Rv1260|M.tuberculosis_H37Rv IELLRDDLVELLYGAT-QPSVEYLFDDSISTLQDDGDSVRVTFERAAARE
Mb0590c|M.bovis_AF2122/97 TSLPRGDLAAAIYTTI-EDQVETIFDDSIATIDEHRDGVRLTFERTAPRD
Mvan_5278|M.vanbaalenii_PYR-1 YPIARAELQLMLMKAYGIDDINFGMKMVGVENDTAGSAAKATFADGTTVS
: * :* : . : : :* .
MMAR_4675|M.marinum_M FDIVVGADGLHSNVRRLVFG-EDAGHTQFLGGYLAVVSVPKGLAHDGEMV
MUL_0294|M.ulcerans_Agy99 FDIVVGADGLHSNVRRLVFG-EDAGHTQFLGGYLAVVSVPKGLAHDGEMV
MAV_0984|M.avium_104 FDVVVGADGLHSNVRRLTFG-DEAGLTRFLGGYLSVVSAPKTLVGPGEMV
MSMEG_5719|M.smegmatis_MC2_155 FDVVVGADGLHSGVRRLVFG-DNVSEN-FLAGYLSVVSVPKSLARDGEMT
MAB_2678|M.abscessus_ATCC_1997 FDLVIGADGLHSHVRGLVFG-PESGYSHWLGQYLAVASIPNYLDLSDRAL
Rv1260|M.tuberculosis_H37Rv FDLVIGADGLHSNVRRLVFG-PEEQFVKRLGTHAAIFTVPNFLELDYWQT
Mb0590c|M.bovis_AF2122/97 FDLVIGADGLHSNVRRLVFG-PERDFEHYLGCKVAACVVDGYRPRD--ER
Mvan_5278|M.vanbaalenii_PYR-1 ADVIIGADGAGSITREYVLGGPVSRRYAGYVNYNGLVSTDDAIGPATEWT
*:::**** * .* .:* .
MMAR_4675|M.marinum_M GHVGPGRMAAVYTAAPLDDARLLFLFRTQEELQYHYRDVLRQKELLREAI
MUL_0294|M.ulcerans_Agy99 GHVGPGRMAAFYTAAPLDDAHLLFLFRTQEELRYHYRDVLRQKELLREAI
MAV_0984|M.avium_104 GHVGVGRFAGIYTADHLDDARAVFLFRSAAELAYDHRDTARQKELLREAF
MSMEG_5719|M.smegmatis_MC2_155 SFLKPGHMAAVYTADHLEDARAVFIFRPSRPLDYDHRDVERQKAQLRAAF
MAB_2678|M.abscessus_ATCC_1997 MYPQVDKIAGMYSAAQLSDARAFFLFRTPEPLDYHHRDVGRQKALLGEVY
Rv1260|M.tuberculosis_H37Rv WHYGDSTMAGVYSARNNTEARAALAFMDT-ELRIDYRDTEAQFAELQRRM
Mb0590c|M.bovis_AF2122/97 SYVLYNTVDRQLARFALRGDRTMFLFVFRAEHDNPG---VAPKDELRDQF
Mvan_5278|M.vanbaalenii_PYR-1 TYVGDG---KRVSVMPVSDDRFYFFFDVVEPQGSPYEE-GRVREVLRAHF
. . : : : * *
MMAR_4675|M.marinum_M AGMHPQVDLWLEELDRTPAFYFDSITQLQLDTWSRGRVTLVGDAGYCPGP
MUL_0294|M.ulcerans_Agy99 AGIHPQVDLWLEELDRTPAFYFDSITQLQLDTWSRGRVTLVGDAGYCPGP
MAV_0984|M.avium_104 AGMHDEVDGWLAETERTPTFYFDSITQLRTDRWSRRRVTLVGDAGYCPGP
MSMEG_5719|M.smegmatis_MC2_155 EHIAPEVDRWLDEVPRTPAFYFDAITQLEMTTWSRGRVTLVGDAGYCPGP
MAB_2678|M.abscessus_ATCC_1997 ADVGWELPRMLAEVDATDTFYMDSITQLRMDTWSKGRITLVGDAGYCPGP
Rv1260|M.tuberculosis_H37Rv AEDGWVRAQLLHYMRSAPDFYFDEMSQILMDRWSRGRVALVGDAGYCCSP
Mb0590c|M.bovis_AF2122/97 GDVGWESRDILAALDDVEDLYFDVVSQIRMDRWSRGRVLLIGDAAGCISL
Mvan_5278|M.vanbaalenii_PYR-1 AGWTPGVQTLIDTLDPLATNRVEILDLDPFHTWVKGRVAVLGDAAHNTTP
: .: : * : *: ::***.
MMAR_4675|M.marinum_M AVGGSTSLSVLGAYILAGELAQAGGDYARAFAAYEREMADPVSRSRAFAS
MUL_0294|M.ulcerans_Agy99 AVGGSTSLSVLGACILAGEPAQAGGDYARAFAAYEREMADPVSRSHTFAS
MAV_0984|M.avium_104 AVGGSTSLAVLGAYVLAGELARADGDHLRAFAAYELQMRESVRRSRSFAR
MSMEG_5719|M.smegmatis_MC2_155 AVGGSTSLAVYGAYVLAAEMVRAGEDYPAAFDAYERTMLAPVVGSRKLAR
MAB_2678|M.abscessus_ATCC_1997 AVGGSTSLAVVGAYVLAGEIAAAAGDHARAYPAYEAALREYVEVSRKLAL
Rv1260|M.tuberculosis_H37Rv LSGQGTSVALLGAYILAGELKAAGDDYQLGFANYHAEFHGFVERNQWLVS
Mb0590c|M.bovis_AF2122/97 LGGEGTGLAITEAYVLAGELARAGGDHRRAFDAYEKRLRPFIEGKQASAA
Mvan_5278|M.vanbaalenii_PYR-1 DIGQGGCSAMEDAIALQWAFKDHPDDVHAALAAYQSARTERAADLVLRAR
* . :: * * * . *. .
MMAR_4675|M.marinum_M GVAVSLIPRSKAGVWALTHGAQLVSMLPGGLTKAVAKLNTKG-VRLYDSM
MUL_0294|M.ulcerans_Agy99 GVAVSLIPRSKAGVWALTHGAQLVSMLPGGLTKAVAKLNTKG-VRLYDSM
MAV_0984|M.avium_104 AAARGVIPGSRAGVWALTRGAQLVSAMPTSLARALAKLNTKG-VRMHDSM
MSMEG_5719|M.smegmatis_MC2_155 FNAKTVVPASGLGIRALVGVGQLISVLPVGLTRSLARLNDKG-VRLYDTM
MAB_2678|M.abscessus_ATCC_1997 TASGTLVPKSRLGLCTLVHGARILGHLPSSLTRSLSRLVAARRINIHDTF
Rv1260|M.tuberculosis_H37Rv DN----IPGG-------------------------APIPQEEFERIVHSI
Mb0590c|M.bovis_AF2122/97 KFIWFFRHPN-----------------------PIRPVVSQRCDAHDELR
Mvan_5278|M.vanbaalenii_PYR-1 KRCDVTHAKD----------PQVTSRWYDELRNEDGTNIIRGIVGNIVGG
.
MMAR_4675|M.marinum_M RFKEYAPPRPG
MUL_0294|M.ulcerans_Agy99 RFKEYAPPRPG
MAV_0984|M.avium_104 PVPDYAGSDV-
MSMEG_5719|M.smegmatis_MC2_155 PLPQWPARLNG
MAB_2678|M.abscessus_ATCC_1997 ALRDYQGLISR
Rv1260|M.tuberculosis_H37Rv TIKDY------
Mb0590c|M.bovis_AF2122/97 PAGDAVRRQRA
Mvan_5278|M.vanbaalenii_PYR-1 PLTPVTAATEG