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LFDAALAEISQRGLAAADVSAIVADAGVARGTFYFHFPTKEHVLVEVERAEETRIVSELGGATGDLAAVL NQLVQHVLSAEKRLGPAVFRDMLGLHFCSTRPVEDELAQHPLGQFLVGVIGRAQDAGQVASDVDAAELAT FFLTGLFALLATGAHDGALLSHYVTTIVKGMEKR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4190 | - | - | 100% (174) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_2459 | - | 6e-36 | 46.07% (178) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_3803 | - | 4e-08 | 37.97% (79) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2534 | - | 3e-05 | 30.20% (149) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1774 | - | 5e-37 | 45.00% (180) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv2506 | - | 3e-05 | 30.20% (149) | TetR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3565 | - | 3e-08 | 30.34% (178) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0249 | - | 1e-57 | 63.54% (181) | TetR family transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_6604 | - | 5e-34 | 48.39% (155) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_1791 | - | 2e-38 | 47.51% (181) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_4864 | - | 6e-57 | 62.98% (181) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4973 | - | 2e-38 | 44.44% (180) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0249|M.marinum_M -MGSTASTTAPHSPQQKVREAQRLRTRARVFDAAVAEIGRRGLAGADVAA
MUL_4864|M.ulcerans_Agy99 -MGSTASTTAAHSPQQKVREAQRLRTRARVFDAAVAEIGRRGLAGADVAA
MAV_4190|M.avium_104 -----------------------------MFDAALAEISQRGLAAADVSA
MSMEG_6604|M.smegmatis_MC2_155 ---------MAGADGLTAREAKRLQTRERLMGAAIAEFKRAGMADADVGT
TH_1791|M.thermoresistible__bu ----------VLNERTSDRGSKGRQTRERLLGAAIAEFKRGGMAAADVAS
Mflv_1774|M.gilvum_PYR-GCK ---------MTPQIKQSARELRRLQTRERILGAAIAEFQASGMAGADVGA
Mvan_4973|M.vanbaalenii_PYR-1 --------MMAPQVRQTARELRRLQTRERILGAAIAEFQASGMAGADIGA
Mb2534|M.bovis_AF2122/97 MTASAPDGRPGQPEATNRRSQLKSDRRFQLLAAAERLFAERGFLAVRLED
Rv2506|M.tuberculosis_H37Rv MTASAPDGRPGQPEATNRRSQLKSDRRFQLLAAAERLFAERGFLAVRLED
MAB_3565|M.abscessus_ATCC_1997 -------MANRQTVQGVRTGGRSARVREAILDAAFGELIDRGYAELTMEA
:: ** : * :
MMAR_0249|M.marinum_M IAAAAGVARGTFYFHFPTKEHVLVELERAEELAIVAKLRDPTADPTDLVS
MUL_4864|M.ulcerans_Agy99 IAAAAGVARGTFYFHFPTKEHVLVELERAEELAIVAKLRDPTADSTDLVS
MAV_4190|M.avium_104 IVADAGVARGTFYFHFPTKEHVLVEVERAEETRIVSELGGATG---DLAA
MSMEG_6604|M.smegmatis_MC2_155 IVAAAGVAHGTFFFHFPTKEHVLLELEQREEERIAKQFAQFVKKPHDLEA
TH_1791|M.thermoresistible__bu IVAAAGVAHGTFFFHFPTKEHVLVELERREEERMAAELNRYFRTPHTVRQ
Mflv_1774|M.gilvum_PYR-GCK IVSAAGVAHGTFFFHFPSKEHVLLELERREEARMATEFVRYLRRSHDLTA
Mvan_4973|M.vanbaalenii_PYR-1 IVSAAGVAHGTFFFHFPSKEHVLLELERREESRMATEFARYLDKKHDLAS
Mb2534|M.bovis_AF2122/97 IGAAAGVSGPAIYRHFPNKESLLVELLVGVSARLLAGARDVTTRSANLAA
Rv2506|M.tuberculosis_H37Rv IGAAAGVSGPAIYRHFPNKESLLVELLVGVSARLLAGARDVTTRSANLAA
MAB_3565|M.abscessus_ATCC_1997 VASRAGVNKTTIYRRWPTLEDLLVEALTTWSLEAIPIPETGSIESDLLST
: : *** ::: ::*. * :*:* . :
MMAR_0249|M.marinum_M VLSSLVHQVVAVERRLGPVVFRDMLGLHFAPTRPVEDQLGEHPLAEFVIE
MUL_4864|M.ulcerans_Agy99 VLSSLAHQVVAVERRLGPLVFRDMLGLHFAPTRPVEDQLGEHPLAEFVIE
MAV_4190|M.avium_104 VLNQLVQHVLSAEKRLGPAVFRDMLGLHFCSTRPVEDELAQHPLGQFLVG
MSMEG_6604|M.smegmatis_MC2_155 ALREIVRLVIGLERRLGDLLFKDFLALHFSQTRPRVDEGMEHPVIARVTE
TH_1791|M.thermoresistible__bu TLAEIVRLLEDLERRLGTRLFKDFLALHFSTTRPPSEEWSRHPVIAAVVE
Mflv_1774|M.gilvum_PYR-GCK ALTKVVGLIAGLEQRLGPVLFRELLALHFSPTRPSDDDWSDHPVIVSLVR
Mvan_4973|M.vanbaalenii_PYR-1 ALAKVVELISALERRFGPLLFKELLALHFSPTRPSTDEWSDHPVIVSLVG
Mb2534|M.bovis_AF2122/97 ALDGLIEFHLDFALGEADLIRIQDRDLAHLPAVAERQVRKAQRQYVEVWV
Rv2506|M.tuberculosis_H37Rv ALDGLIEFHLDFALGEADLIRIQDRDLAHLPAVAERQVRKAQRQYVEVWV
MAB_3565|M.abscessus_ATCC_1997 GRELAAVLNDGVGRQVAALVLT--AGLRSAPLREATRRYFDHQVLR-AAP
. : * :
MMAR_0249|M.marinum_M TIARAQRANRVPPDADAGELGVIFLTGLFALLATGATTPD----ARTALL
MUL_4864|M.ulcerans_Agy99 TIAQAQRADRVAPDADAGELGVIFLTGLFALLATGATTPD----ARTALL
MAV_4190|M.avium_104 VIGRAQDAGQVASDVDAAELATFFLTGLFALLATGAHDG--------ALL
MSMEG_6604|M.smegmatis_MC2_155 EIEAARQRGDVAADVNPVNSAVFFLLGFYALLVTTND-----WPTRDEVL
TH_1791|M.thermoresistible__bu ELQRARDRGEIPEDVDVMHNGVSFLTGLYALLITMPESHDLRAPALSEYL
Mflv_1774|M.gilvum_PYR-GCK EIERARGDGEVHPEVDAFFSAAFFLLGVYGVLTTVTS-----SDTRDAML
Mvan_4973|M.vanbaalenii_PYR-1 AIERARGDGEIHPEVDAFYSAAFFLLGIYGVLTTVAR-----GDIRDAML
Mb2534|M.bovis_AF2122/97 GVLRELNPGLAEADARLMAHAVFGLLNSTPHSMKAADSKPARTVRARAVL
Rv2506|M.tuberculosis_H37Rv GVLRELNPGLAEADARLMAHAVFGLLNSTPHSMKAADSKPARTVRARAVL
MAB_3565|M.abscessus_ATCC_1997 VVRQAIDRGELPADCDVDMLLTTFRAPLFYRTITTGDP------IDDALI
: . : . . :
MMAR_0249|M.marinum_M NRFVTTVVHGMEAR----
MUL_4864|M.ulcerans_Agy99 NGFVTTVVHGMEAR----
MAV_4190|M.avium_104 SHYVTTIVKGMEKR----
MSMEG_6604|M.smegmatis_MC2_155 DDYVR-RTLRSMRP----
TH_1791|M.thermoresistible__bu TTYVHGMRVRSDPPAIAR
Mflv_1774|M.gilvum_PYR-GCK ANLITTARRGLESR----
Mvan_4973|M.vanbaalenii_PYR-1 ANLITTARRGLETR----
Mb2534|M.bovis_AF2122/97 RAMTVAALSAADRCL---
Rv2506|M.tuberculosis_H37Rv RAMTVAALSAADRCL---
MAB_3565|M.abscessus_ATCC_1997 IHATQITLTAARAGLLSA