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VPLRQAQALATRQRLVDVATELFALHGFTSVTTTSLSEASGMTRGALYHHFANMTEVMEAVFERAEGFLV AEVNHSLTSIESPAERFLAIGSAVLDVLAREPIVQRIVFVEAPMALGWSRWRALDGGRSLGLIQDILEEL YRRGELVEAVDPQMAAQLILGAINESGMYAAAAPSERSSRAAEQLTLLCRGLLSPRSG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4352c | - | - | 100% (199) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2290 | - | 6e-15 | 29.44% (197) | transcriptional regulator TetR |
| M. abscessus ATCC 19977 | MAB_4912c | - | 2e-09 | 33.68% (95) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0080 | - | 5e-21 | 30.61% (196) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_0973 | - | 3e-08 | 38.03% (71) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0078 | - | 6e-21 | 30.10% (196) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_02677 | - | 4e-14 | 28.57% (168) | putative TetR-family transcriptional regulator |
| M. marinum M | MMAR_0224 | - | 1e-19 | 28.21% (195) | transcriptional regulatory protein |
| M. avium 104 | MAV_5253 | - | 1e-22 | 32.99% (197) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_2193 | - | 4e-11 | 27.55% (196) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_3094 | - | 6e-18 | 33.82% (204) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_4890 | - | 2e-19 | 28.21% (195) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_0170 | - | 6e-09 | 26.40% (197) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0224|M.marinum_M MEIKRRTQEER---SAATREALITAARKLWGSRGYAEVGTPEIAAEAGV-
MUL_4890|M.ulcerans_Agy99 MESKRRTQEER---SAATREALITAARKLWGSRGYAEVGTPEIAAEAGV-
Mb0080|M.bovis_AF2122/97 MEIKRRTQEER---SAATREALITGARKLWGLRGYAEVGTPEIATEAGV-
Rv0078|M.tuberculosis_H37Rv MEIKRRTQEER---SAATREALITGARKLWGLRGYAEVGTPEIATEAGV-
MAV_5253|M.avium_104 MESKRRTQEER---SAATRDALIAAARKLWGLRGYTEVGTPEIAAAAGV-
MLBr_02677|M.leprae_Br4923 MESQRRTQEER---STATRDALTLARHRLWRLRGYAEVGTPEIAKEADT-
TH_3094|M.thermoresistible__bu MSKRGGRVEDRRARGDQTRRDLIDAGRALFVDPGYFHTSVGDLVERSGVG
MAB_4352c|M.abscessus_ATCC_199 MVPLRQAQALA------TRQRLVDVATELFALHGFTSVTTTSLSEASGM-
Mflv_0973|M.gilvum_PYR-GCK MSGDSTRAGGP------TRRRLIDVAIELFKRYSVAGTSLQMISDELGL-
Mvan_0170|M.vanbaalenii_PYR-1 MTTASSAQMPPQ----SARQRVLDVALALFTRHGYAGTSLQMIADEMGV-
MSMEG_2193|M.smegmatis_MC2_155 MARQARAGVTR--------RKIITAAVDLFAEIGYPATGLGEIIERADM-
* : *: . . : .
MMAR_0224|M.marinum_M TRGAMYHQFADKAALFGEVVEAVEQDVMTRMATSVAASGAATPADAIRAA
MUL_4890|M.ulcerans_Agy99 TRGAMYHQFADKAALFGEVVEAVEQDVMTRMATSVTTSGAATPADAIRAA
Mb0080|M.bovis_AF2122/97 TRGAMYHQFADKAALFRDVVEVVEQDVMARMATLVAASGAATPADAIRAA
Rv0078|M.tuberculosis_H37Rv TRGAMYHQFADKAALFRDVVEVVEQDVMARMATLVAASGAATPADAIRAA
MAV_5253|M.avium_104 TRGAMYHQFADKAALFRAVVEAVEQDVMARMAVVVAESGASTPTDAIRAA
MLBr_02677|M.leprae_Br4923 TRGAVYHQFTDKAALFRDVVETVEQDAMAQIASVVASSGAKTPVDAIRAK
TH_3094|M.thermoresistible__bu TRGAFYHHFPDKAALFRAVFEDVEQDLTLRSIASPPEG--SDSWERLTRG
MAB_4352c|M.abscessus_ATCC_199 TRGALYHHFANMTEVMEAVFERAEGFLVAEVNHS--LTSIESPAERFLAI
Mflv_0973|M.gilvum_PYR-GCK TKSAIYHHFRTRDELLTAVMEPLIAEVAEIVDAAEEQRTPHARADHMLVG
Mvan_0170|M.vanbaalenii_PYR-1 TKGSLYYHFRAREDLLRALVGPLIEQLRAIVEHAEAQRSPSVRAEHVLTG
MSMEG_2193|M.smegmatis_MC2_155 TKGALYYHFDSKEALAEAIIAESGASMLAAFQNITETS--SPALENLIHG
*:.:.*::* : :. : .
MMAR_0224|M.marinum_M VDAWLEVSG-DPEVRQLILLDAPAVLGWAGFRDVAQRYSLGMTEQ-LITE
MUL_4890|M.ulcerans_Agy99 VDAWLEVSG-DPEVRQLILLDAPAVLGWAGFCDVAQRYSLGMTEQ-LITE
Mb0080|M.bovis_AF2122/97 VDAWLEVSG-DPEVRQLVLLDAPVVLGWAGFRDVAQRYSLGMTEQ-LITE
Rv0078|M.tuberculosis_H37Rv VDAWLEVSG-DPEVRQLILLDAPVVLGWAGFRDVAQRYSLGMTEQ-LITE
MAV_5253|M.avium_104 VDAWLEVSA-DPEVRQLILLDAPSVLGWAEFRDVAQRYSLGMTEQ-LLTE
MLBr_02677|M.leprae_Br4923 VDAWLEGLA-DPQVRQLILLYAPSVLGWAAFRDVAQHYSLGMTEQQLLSE
TH_3094|M.thermoresistible__bu LHGFLDAAA-EPEVQRIILIDGPVVLGWQTLRSIEERSSLAMIQQ-ILRR
MAB_4352c|M.abscessus_ATCC_199 GSAVLDVLAREPIVQRIVFVEAPMALGWSRWRALDGGRSLGLIQDILEEL
Mflv_0973|M.gilvum_PYR-GCK YASIAARHR------TLIPLLSGDPGVVALLRTRSEWGDLVRRQLALFSE
Mvan_0170|M.vanbaalenii_PYR-1 YARLAAANR------ALVAVTSGDPSVVEVIHADPDWADLIDRQIGLLAA
MSMEG_2193|M.smegmatis_MC2_155 LFVVCDFTR-TDRVADIGLHLLQTFAGINDTTARVYASWLDAISAQLHRA
: * . :
MMAR_0224|M.marinum_M AIRAGQLDRHPVRPLAHVLIGALDEAAMFIATAD-----DPKR-------
MUL_4890|M.ulcerans_Agy99 AIRAGQLDRHPVRPLAHVLIGALDEAAMFIATAD-----DPKR-------
Mb0080|M.bovis_AF2122/97 AIRAGQLARQPVRPLAQVLIGALDEAAMFIATAD-----DPKR-------
Rv0078|M.tuberculosis_H37Rv AIRAGQLARQPVRPLAQVLIGALDEAAMFIATAD-----DPKR-------
MAV_5253|M.avium_104 AIRAGELAEQPVRPLAHVLIGALDEAAMVIATAD-----DPDR-------
MLBr_02677|M.leprae_Br4923 ASRARQLA----QPLDHVLIGKLYESAMAIRRHHRLPEASPARNQTGAAP
TH_3094|M.thermoresistible__bu AIADGSIEEQPVTALTHMLVSAVEEASLLIAHST-----DPER-------
MAB_4352c|M.abscessus_ATCC_199 YRRGELVEAVDPQMAAQLILGAINESGMYAAAAP------SERS------
Mflv_0973|M.gilvum_PYR-GCK VEPGLGGQVKAALAMSGIASAAGVDYGGDVDDDT----------------
Mvan_0170|M.vanbaalenii_PYR-1 VQPGLAGRVRATIVMAGIAATAAPGVV-EADEAE----------------
MSMEG_2193|M.smegmatis_MC2_155 AAEGDLREGLDPGAVADVVLSALLGAEALTRAGTSG---TDLR-------
:
MMAR_0224|M.marinum_M ------AR------------RESRQVLRRLIDGMLND-------------
MUL_4890|M.ulcerans_Agy99 ------AR------------RESRQVLRRLIDGMLND-------------
Mb0080|M.bovis_AF2122/97 ------AR------------RETRQVLRRLIDGMLNG-------------
Rv0078|M.tuberculosis_H37Rv ------AR------------RETRQVLRRLIDGMLNG-------------
MAV_5253|M.avium_104 ------AR------------RETRQVLQRLVDGMFDAR------------
MLBr_02677|M.leprae_Br4923 THREHVARPSCEALTRHIRHRSTRTRSHRGKRGELLPRAATSSLL-----
TH_3094|M.thermoresistible__bu -AR-----------------SDAEAVLDTLLNALTRRRSRSR--------
MAB_4352c|M.abscessus_ATCC_199 --------------------SRAAEQLTLLCRGLLSPRSG----------
Mflv_0973|M.gilvum_PYR-GCK -------------------LRDQLIAAGRRALGLRNSRTGAVTARR----
Mvan_0170|M.vanbaalenii_PYR-1 -------------------LCRQLIDAGRRTLGLRAPRA-----------
MSMEG_2193|M.smegmatis_MC2_155 --------------------ERLVRTWDLLLPALVEPASLDYFREFLARE
.
MMAR_0224|M.marinum_M ---------
MUL_4890|M.ulcerans_Agy99 ---------
Mb0080|M.bovis_AF2122/97 ---------
Rv0078|M.tuberculosis_H37Rv ---------
MAV_5253|M.avium_104 ---------
MLBr_02677|M.leprae_Br4923 ---------
TH_3094|M.thermoresistible__bu ---------
MAB_4352c|M.abscessus_ATCC_199 ---------
Mflv_0973|M.gilvum_PYR-GCK ---------
Mvan_0170|M.vanbaalenii_PYR-1 ---------
MSMEG_2193|M.smegmatis_MC2_155 SMRRSPGTD