For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4573 | - | - | 100% (204) | putative transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_3720 | - | 3e-24 | 31.28% (195) | PUTATIVE transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2255 | - | 1e-09 | 30.89% (123) | TetR-family protein transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1561 | - | 4e-10 | 26.67% (210) | transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2304 | - | 2e-18 | 31.09% (193) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1534 | - | 4e-10 | 26.67% (210) | transcriptional regulator |
| M. leprae Br4923 | MLBr_02677 | - | 4e-05 | 23.93% (117) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0098 | - | 1e-21 | 34.39% (189) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4251 | - | 1e-24 | 31.91% (188) | transcriptional regulator |
| M. avium 104 | MAV_1333 | - | 7e-27 | 34.39% (189) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_4953 | - | 2e-18 | 31.38% (188) | putative transcriptional regulator |
| M. ulcerans Agy99 | MUL_0934 | - | 2e-24 | 31.91% (188) | transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4342 | - | 4e-17 | 29.53% (193) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1561|M.bovis_AF2122/97 --------MSRASARRRRAVSDED-------------KSQRRDEILAAAK
Rv1534|M.tuberculosis_H37Rv --------MSRASARRRRAVSDED-------------KSQRRDEILAAAK
Mflv_2304|M.gilvum_PYR-GCK --------MSMSVGAFANSAPADQVTSPVADPPVEPKARTVRDRLIDAAE
Mvan_4342|M.vanbaalenii_PYR-1 --------MSMSVGTVPNSAGSNSAASARAEP------GSVRDRLIDAAE
MSMEG_4953|M.smegmatis_MC2_155 ----------MTNATAP---------------------RSVRDRLIDAAE
MMAR_4251|M.marinum_M --------MPQSAALPQ--------------------ATDTRELIIGSAY
MUL_0934|M.ulcerans_Agy99 MPPPDELVMPQSAALPQ--------------------ATDTRELIIGSAY
MAV_1333|M.avium_104 ----------MSTDVSP--------------------ATDTRELIVAAAF
TH_4573|M.thermoresistible__bu --------MATQRATADVEEQHE---------------SDRRDQILEAAN
MAB_0098|M.abscessus_ATCC_1997 --------MKLVKTTGP--------------------RGEVPEPIVAAVA
MLBr_02677|M.leprae_Br4923 --------MESQRRTQEER------------------STATRDALTLARH
: : :
Mb1561|M.bovis_AF2122/97 IVFAHKGFHATTVADIAKQAGLAYGLIYWYFDSKDDLFHALMAGEEEALR
Rv1534|M.tuberculosis_H37Rv IVFAHKGFHATTVADIAKQAGLAYGLIYWYFDSKDDLFHALMAGEEEALR
Mflv_2304|M.gilvum_PYR-GCK QCLTAKGIRATTVSEVAEVAGVSRGWLYRHFPDKSELLGAAIVRLNDAFW
Mvan_4342|M.vanbaalenii_PYR-1 QCLTAKGIRATTVSEVAEVAGVSRGWLYRHFPDKAELLGAAIVRLNDAFW
MSMEG_4953|M.smegmatis_MC2_155 TCLRAKGIRATTVSEVAEAAGVSRGWLYRHFPDKVSLLGAAIVRLNDAYW
MMAR_4251|M.marinum_M VCFRRQGFQKTTIVDIARLANVSRSTIYEYFRDKAAIMEGCAERASEQFY
MUL_0934|M.ulcerans_Agy99 VCFRRQGFQKTTIVDIARLANVSRSTIYEYFRDKAAIMEGCAERASEQFY
MAV_1333|M.avium_104 TCFGRQGLQKATIVDIAKQAGVSRSTIYEYFSDKAAIVEACAEHASERFY
TH_4573|M.thermoresistible__bu ACFAQLGIHRTSVQDVARAANVSRGTVYRYFEDRTILIEAAIEYGAQKFY
MAB_0098|M.abscessus_ATCC_1997 QTLVRSGIQRFSLSAAADEAGVSRGTIYNWFGGKKEAIDVAVGFIAGAFI
MLBr_02677|M.leprae_Br4923 RLWRLRGYAEVGTPEIAKEADTTRGAVYHQFTDKAALFRDVVETVEQDAM
* * *. : . :* * .: .
Mb1561|M.bovis_AF2122/97 AHVAAELARVGGSTEAPLRALLQAAVQATFEFFETDKATVKLLFRDAYAL
Rv1534|M.tuberculosis_H37Rv AHVAAELARVGGSTEAPLRALLQAAVQATFEFFETDKATVKLLFRDAYAL
Mflv_2304|M.gilvum_PYR-GCK TESRTRLDSVTGLDEQ----IAAGVALARKESETPGALVLKLRQEEPEAF
Mvan_4342|M.vanbaalenii_PYR-1 SESRTRLDAVAGLDQQ----IAVGVELARKESETPGALVLKLRQEEPEAF
MSMEG_4953|M.smegmatis_MC2_155 SDAHAFLAAYDGLDEK----IAAGIRYGRTAYDDPGALLMKLRLDEPEEF
MMAR_4251|M.marinum_M REMSKAMDRGGSLQEK----LCQAAVFVTQSRQ----AIASAKYFDEDAI
MUL_0934|M.ulcerans_Agy99 REMSKAMDRGGSLQEK----LCQAAVFVTQSRQ----TIASAKYFDQDAI
MAV_1333|M.avium_104 REMAKAMDRGGTLEER----LCAAAVFVTQARR----VIASEKYFDEDAI
TH_4573|M.thermoresistible__bu QEIAAAMAKKSTLAEQ------LGAMAETHAKILLDHRTRNRLMTDDAEL
MAB_0098|M.abscessus_ATCC_1997 ELFAGAVSAKTTLTDQ------VGEAAVRISDHRAWSDRLDPTLHVSNVL
MLBr_02677|M.leprae_Br4923 AQIASVVASSGAKTPVD---AIRAKVDAWLEGLADPQVRQLILLYAPSVL
: . :
Mb1561|M.bovis_AF2122/97 GGRFEEHLGGIYERFIDDIEAVVVAAQRR-----------GEVVEAP-SR
Rv1534|M.tuberculosis_H37Rv GGRFEEHLGGIYERFIDDIEAVVVAAQRR-----------GEVVEAP-SR
Mflv_2304|M.gilvum_PYR-GCK TACVGLGVRGLIPEIAAFWEPYIQAAVDR-----------GEIHADTDRA
Mvan_4342|M.vanbaalenii_PYR-1 TACVGLGVRGLIPEIAAFWVPYIQAAVDR-----------GEIHPDTNSA
MSMEG_4953|M.smegmatis_MC2_155 AACAGAGVQGLVPDLAAFWTRYLLAARDT-----------GEIHPNTDIA
MMAR_4251|M.marinum_M SLLLTKDSAVLLRECIDFFAPYLAAAKLT-----------GEVRKDLDVQ
MUL_0934|M.ulcerans_Agy99 SLLLTKDSAVLLRECIDFFAPYLAAAKLT-----------GEVRKDLDVQ
MAV_1333|M.avium_104 SLLLTKDAAVLLRECVEFFAPYLAAARLT-----------GEVRKDLDVE
TH_4573|M.thermoresistible__bu MRHMIADADAAVRRTTEFLMPYVQQAKER-----------GEVGSGVDVK
MAB_0098|M.abscessus_ATCC_1997 ELVLEECGDDLMRRSVEFWVPQVEAAKHR-----------GEIGGDVDAT
MLBr_02677|M.leprae_Br4923 GWAAFRDVAQHYSLGMTEQQLLSEASRARQLAQPLDHVLIGKLYESAMAI
: *::
Mb1561|M.bovis_AF2122/97 MAAYTLAALVGQLAHRRL-NTDDNVTAAQVADFVVSLVLDGLRPRALAVG
Rv1534|M.tuberculosis_H37Rv MAAYTLAALVGQLAHRRL-NTDDNVTAAQVADFVVSLVLDGLRPRALAVG
Mflv_2304|M.gilvum_PYR-GCK EAAEWIARITMSLATVPG-EQCDVDDHESVLRHARRYIVAAFRSD---PA
Mvan_4342|M.vanbaalenii_PYR-1 EAAEWIARIMMSLATVPG-EQCNVDDHDSVLRHARRYIVAALRSD---PN
MSMEG_4953|M.smegmatis_MC2_155 EAAEWVARVVISFATVPG-EQLDASDTGAVLTHLRRYVMPGLRAE---PA
MMAR_4251|M.marinum_M AAAEWFARILFSLFSTPS-PIRDMDDAQAVTEFVRAHVVDGFSDSRWRPA
MUL_0934|M.ulcerans_Agy99 AAAEWFARILFSLFSTPS-PIRDMDDAQAVTEFVRAHVVDGFSDSRWRPA
MAV_1333|M.avium_104 AAGEWFARILFSLFSTPS-PTLNLDDPDVTAEFVRAHVVRGFASE--RPR
TH_4573|M.thermoresistible__bu AASEWLARIIYSFTTVNEGLTFDMSKPATVRRYVERFAVNGLR-------
MAB_0098|M.abscessus_ATCC_1997 EAAEWIMRTLMSIEVLPA-ISVDLTDPNRVRRYFSRFILRGLA-------
MLBr_02677|M.leprae_Br4923 RRHHRLPEASPARNQTGAAPTHREHVARPSCEALTRHIRHRSTRTRSHRG
.
Mb1561|M.bovis_AF2122/97 ARGGRAART------
Rv1534|M.tuberculosis_H37Rv ARGGRAART------
Mflv_2304|M.gilvum_PYR-GCK GT-------------
Mvan_4342|M.vanbaalenii_PYR-1 Q--------------
MSMEG_4953|M.smegmatis_MC2_155 S--------------
MMAR_4251|M.marinum_M RGVSKVH--------
MUL_0934|M.ulcerans_Agy99 RGVSKVH--------
MAV_1333|M.avium_104 RR-------------
TH_4573|M.thermoresistible__bu ---------------
MAB_0098|M.abscessus_ATCC_1997 ---------------
MLBr_02677|M.leprae_Br4923 KRGELLPRAATSSLL