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TIKRPVRQSLSCAIRRLSIPIVIGWIALSAYLTVGLPPLEVVGQLHSVSMNPRDAPSAVAMRRIGELFKE SDSDNTAMILLEGDQPLGDNAHYYYNNLVRQLSSDTTHVQHIQNFWGDPLTAEGAQSTDGKAAYVQLNLA GNMGGPLANQSIEAVRQILARTPPPPGIKVYVTGPSALTADMSRTGDKSLVIVTMISVLVIFTMLLLVYR SIVTVTLLLITVGIELTAARGVVAFLAWHGVIGLSTYAINLLTTMAIAAGTDYSIFIIGRYQEARQAGED AETAFYTMYRGVAHVILGSGLTIAGAMYCLTFTRMPYFQSMGIPCAAGMLVAVVAALTMGPAVLALGSRF GLFDPKRKIKTRGWRRIGTAVVRWPAPILTATCAVSLVGLIALPGYQTNYDDQTYVPENIPANAGYAAAN RHFPPSRMKPDVLLIVADHDMRNSADFLVLDKLAKGIFHVPGISRVQAITRPKGTPIEHTSIPFQISMQN AGQLQNMKYQRDRMNDMLTQADQLTSTIALMKRTYDLMLQMSKTTHRMVGDTLEMKSVTDELRDHIADFE DTWRPIRSYFYWEKHCADIPICWSLRSIFDALDGVDQVSEQLTTLTGDLTDMDRILPQVVATFPQMIQNM EGMRTLILTMHSTMSGIYDQMDELSKNSTAMGQAFDAAKNDDSFYLPPEVFNNPDFKRGMKMFLSQDGKA ARLFIFHRGNAAGYEGISSISAINIAAAEALKGTPLEDAQIYLTGTAAVYKDIADGSKYDLIIAGLSSLC LIFIIMLLITRGFVAALVIVGTVALSLGVSFGLSVLLWQHLLRIELHWLVLAMSVIVLLAVGSDYNLLLV SRLKEEVGAGIKTGIIRAMGGTGKVVTSAGLVFALTMASMAVSDLIVIGQIGTTIGLGLLFDTLIVRSLM TPSIAALLGRWFWWPLNIRSRPPRLTRQRPLPSVSQEPAAARV*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_0094 | mmpL5_3 | - | 100% (954) | transmembrane transport protein, MmpL5_3 |
M. marinum M | MMAR_0771 | mmpL5_2 | 0.0 | 70.06% (942) | transmembrane transport protein MmpL5_2 |
M. marinum M | MMAR_1877 | mmpL5_1 | 0.0 | 67.33% (952) | transmembrane transport protein, MmpL5_1 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0458c | mmpL4 | 0.0 | 72.16% (934) | transmembrane transport protein MmpL4 |
M. gilvum PYR-GCK | Mflv_4418 | - | 0.0 | 60.11% (945) | transport protein |
M. tuberculosis H37Rv | Rv0450c | mmpL4 | 0.0 | 72.27% (934) | transmembrane transport protein MmpL4 |
M. leprae Br4923 | MLBr_02378 | - | 0.0 | 69.21% (919) | hypothetical protein MLBr_02378 |
M. abscessus ATCC 19977 | MAB_4116c | - | 0.0 | 63.48% (942) | putative membrane protein, MmpL |
M. avium 104 | MAV_3249 | - | 0.0 | 64.36% (912) | Mmp14A protein |
M. smegmatis MC2 155 | MSMEG_0381 | - | 0.0 | 62.49% (933) | Mmp14a protein |
M. thermoresistible (build 8) | TH_3056 | - | 0.0 | 61.14% (929) | PUTATIVE Mmp14a protein |
M. ulcerans Agy99 | MUL_0757 | mmpL5 | 0.0 | 59.66% (952) | transmembrane transport protein, MmpL5 |
M. vanbaalenii PYR-1 | Mvan_3833 | - | 0.0 | 61.28% (922) | transport protein |
CLUSTAL 2.0.9 multiple sequence alignment Mb0458c|M.bovis_AF2122/97 ----MSTKFANDSNTNARPEKPFIARMIHAFAVPIILGWLAVCVVVTVFV Rv0450c|M.tuberculosis_H37Rv ----MSTKFANDSNTNARPEKPFIARMIHAFAVPIILGWLAVCVVVTVFV MLBr_02378|M.leprae_Br4923 ----MTVKCANDLDTHTKP--PFVARMIHRFAVPIILVWLAIAVTVSVFI MMAR_0094|M.marinum_M ----MTIK---------RPVRQSLSCAIRRLSIPIVIGWIALSAYLTVGL MAB_4116c|M.abscessus_ATCC_199 ---------MSADDGKVKSHRPIMATIIRRGAVFIILGWLAITVLLTVKV MSMEG_0381|M.smegmatis_MC2_155 --------MTEPATTQNREARPRIASFIRRFSVLIILAWIVVAALATFAI TH_3056|M.thermoresistible__bu --------MSVLDRVGVEPRRPRVASFIRRYSVLIILGWVALTVLATVAV MAV_3249|M.avium_104 --------------------------------MFIILGWVALTLLVTFGV Mvan_3833|M.vanbaalenii_PYR-1 ---------MRAHADRDLRDPTPVARWIRRLAIPIILGWVLLVAALNLLV Mflv_4418|M.gilvum_PYR-GCK ---------------MADAGRSGIGRIIRVLAVPIVLGWVLLTVLTNVAV MUL_0757|M.ulcerans_Agy99 MTATTTDTPTDVVPPAEHPPRPFIPRMIRTFAVPLILGWVLLIAVLNSVV : ::: *: : . : Mb0458c|M.bovis_AF2122/97 PSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKEGDSDSFAMVIIEGNQP Rv0450c|M.tuberculosis_H37Rv PSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKEGDSDSFAMVIIEGNQP MLBr_02378|M.leprae_Br4923 PSLEDVGQERSVSLSPKDAPSYIAMQKMGQVFNEGNSDSVIMIVLEGDKP MMAR_0094|M.marinum_M PPLEVVGQLHSVSMNPRDAPSAVAMRRIGELFKESDSDNTAMILLEGDQP MAB_4116c|M.abscessus_ATCC_199 PPLEIVEREHSVSLSPPDAPSVKAMTQMGKVFQESNSESVAVIVLEGEGT MSMEG_0381|M.smegmatis_MC2_155 PPLEVVEREHSVSLSPPDAPSVQAMKRMGEVFQESNSNSVAVLVLEGQEP TH_3056|M.thermoresistible__bu PPLEAVEREKSLSLIPYDAPAFAAMHRMGELFDEPDSESIAIIVLEGQEP MAV_3249|M.avium_104 PRLEIVGQQHSVPLAPQDAPAVQAMQRMGRDFKESDSDSFAMLVLEGQQQ Mvan_3833|M.vanbaalenii_PYR-1 PQLEVVAAQNAVSMSPSDAPAMQAMSDMGRLFGESDSDSIAMVVLEGEQP Mflv_4418|M.gilvum_PYR-GCK PSLEKVGEEHTVGMSAGDAPSMMSMKRVGANFEEFDSDSSAMVVLEGEQP MUL_0757|M.ulcerans_Agy99 PQLEVVGQMQAVSMSPDAAPSMISMKHIGKVFREGDSDSAAMIVLEGQEP * ** * .:: : . **: :* :* * * :*:. ::::**: Mb0458c|M.bovis_AF2122/97 LGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDPLTAAGVQSNDGKAAYVQ Rv0450c|M.tuberculosis_H37Rv LGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDPLTAAGVQSNDGKAAYVQ MLBr_02378|M.leprae_Br4923 LGDDAHRFYDGLIRKLRADK-HVQSVQDFWGDPLTAPGAQSNDGKAAYVQ MMAR_0094|M.marinum_M LGDNAHYYYNNLVRQLSSDTTHVQHIQNFWGDPLTAEGAQSTDGKAAYVQ MAB_4116c|M.abscessus_ATCC_199 LGDDAHKYYDAVIRQLKDDPKHVQHVQDFWGDPLTAGAAQSADGKAAYVQ MSMEG_0381|M.smegmatis_MC2_155 LGDDAHRYYDEIIRKLKDDPEHVQHVQDFWGDPLTAGAAESGDRKAAYVQ TH_3056|M.thermoresistible__bu LGLEAHEYYDQLISQLREHPQYVQHIRDFWGDPLTAGAAQSDDGKAAFVQ MAV_3249|M.avium_104 LGDDAHAYYDKLVRELRNDTKHVEHVQDLWGDRLTQAGAQSPDGKAVYVQ Mvan_3833|M.vanbaalenii_PYR-1 LGDDAHAYYDQLIEKLEAAPDHVRNIQDMWGDPLTEAAAQSTDGHAAYVA Mflv_4418|M.gilvum_PYR-GCK LGDAAHRYYDQLIDELEADTANVQHIADFWGDPLTASGAQSTDGKAAYVQ MUL_0757|M.ulcerans_Agy99 LGAAAHKFYDKMITKLRADTKHVQSVQDFWGDPLTATGAQSGDGKAAYVQ ** ** :*: :: :* *. : ::*** ** ..:* * :*.:* Mb0458c|M.bovis_AF2122/97 LSLAGNQGTPLANESVEAVRSIVESTP-APPGIKAYVTGPSALAADMHHS Rv0450c|M.tuberculosis_H37Rv LSLAGNQGTPLANESVEAVRSIVESTP-APPGIKAYVTGPSALAADMHHS MLBr_02378|M.leprae_Br4923 LSLAGNQGELLAQESIDAVRKIVVQTP-APPGITAWVTGASALIADMHHS MMAR_0094|M.marinum_M LNLAGNMGGPLANQSIEAVRQILARTP-PPPGIKVYVTGPSALTADMSRT MAB_4116c|M.abscessus_ATCC_199 LNLTGRFGQADANESVEAVQKVVRETPGLPPGVKAYVTGPAAIVSDMAES MSMEG_0381|M.smegmatis_MC2_155 INLHGSFGQAEANESVKAVQDAVESTP-APPGVQAFVTGPAAIVADMGES TH_3056|M.thermoresistible__bu VNLVGRFGQAKVNEAVRAVQEIVERTP-APEGVETFVTGPAALGADAGDS MAV_3249|M.avium_104 LNLAGNQGTTLGQESVAAVRDVIARIP-PPAGLKAYVTGPAALFSDMQLA Mvan_3833|M.vanbaalenii_PYR-1 LNLAGNMGETKSNESVAAVRDIVADSP-PPPGVQVHVTGPAALTADVNIA Mflv_4418|M.gilvum_PYR-GCK VYLQGNQGEPRANEAVAAVREIVDRTP-APPGIKAYVTGGAPLVADQHSA MUL_0757|M.ulcerans_Agy99 VKLAGNQGESLANESVEAVKTIVDSLQ-APPGVKVYVTGSAALVADQQLA : * * * :::: **: : * *: . *** :.: :* : Mb0458c|M.bovis_AF2122/97 GDRSMARITMVTVAVIFIMLLLVYRSIITVVLLLITVGVELTAARGVVAV Rv0450c|M.tuberculosis_H37Rv GDRSMARITMVTVAVIFIMLLLVYRSIITVVLLLITVGVELTAARGVVAV MLBr_02378|M.leprae_Br4923 GDKSMIRITATSVIVILVTLLLVYRSFITVILLLFTVGIESAVARGVVAL MMAR_0094|M.marinum_M GDKSLVIVTMISVLVIFTMLLLVYRSIVTVTLLLITVGIELTAARGVVAF MAB_4116c|M.abscessus_ATCC_199 GNRTVILITLVSVGVIFLMLLLLYRSIITVIILLFTVGIELQVARGLVAF MSMEG_0381|M.smegmatis_MC2_155 GNKTVLLITLVTVGVIFLMLLLLYRRVLIVLILLATVAIELQVARGLVSF TH_3056|M.thermoresistible__bu GTATVILITLVTVAVIFLMLLFFFRSFLTVIVLLLTVAVELQVARGLVAY MAV_3249|M.avium_104 GDRSILKMTLIGALIIFIVLLFVYRSVTTVVLLLLTVGIEVFAARGVIAF Mvan_3833|M.vanbaalenii_PYR-1 GESSMALILLVTFVVIIVLLLFFYRSITTVVLLLIMVGVQMSVARGVVAA Mflv_4418|M.gilvum_PYR-GCK GDTSVLRVTLITIGVIAVMLLIVFRSVATMVLILFMVFAELGAARGIVAF MUL_0757|M.ulcerans_Agy99 GDRSLQLIEMVTFTVIIVMLLLVYRSIITAAIMLTMVVLGLLATRGGVAF * :: : :* **:.:* . ::* * .:** :: Mb0458c|M.bovis_AF2122/97 LGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFIIGRYQEARQAGEDKEAAY Rv0450c|M.tuberculosis_H37Rv LGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFIIGRYQEARQAGEDKEAAY MLBr_02378|M.leprae_Br4923 LGHTGLIGLSTFAVNLLTSLAIAAGTDYGIFITGRYQEARQANENKEAAF MMAR_0094|M.marinum_M LAWHGVIGLSTYAINLLTTMAIAAGTDYSIFIIGRYQEARQAGEDAETAF MAB_4116c|M.abscessus_ATCC_199 LGMHGIVGLTTFVVNLLVSVGIAAGTDYGIFFAGRYQEARQSGEDRESAY MSMEG_0381|M.smegmatis_MC2_155 LALNGIVGLTTYVVNLLVSVGIAAGTDYGIFFAGRYQEARQAGEDREQAY TH_3056|M.thermoresistible__bu LGLQGWVGLTTYVVNLLVSVGIAAGTDYGIFFFGRYQEAREAGEDRDSAY MAV_3249|M.avium_104 VANNNLMPLSTFAVNLLVALAMAAGTDYAIFFFGRYQEAREAGEDRATAY Mvan_3833|M.vanbaalenii_PYR-1 LGHFQVIGLSTFAVNLLISLAVAAGTDYAIFLVGRYQEARASGADPEAAY Mflv_4418|M.gilvum_PYR-GCK LADAEIIGLSTFATSLLTLMVIAAGTDYAIFAIGRYQEARGAGEDRETAY MUL_0757|M.ulcerans_Agy99 LGYHRIIGLSTFATNLLVVLAIAAATDYAIFLIGRYQEARGLGQDRESAY :. : *:*:. .** : :**.***.** ******* . : *: Mb0458c|M.bovis_AF2122/97 YTMYRGTAHVILGSGLTITGATFCLSFARMPYFQTLGIPCAVGMLVAVAV Rv0450c|M.tuberculosis_H37Rv YTMYRGTAHVILGSGLTIAGATFCLSFARMPYFQTLGIPCAVGMLVAVAV MLBr_02378|M.leprae_Br4923 YTMYRGTFHVILGSGLTISGATFCLSFARMPYFQTLGVPCAVGMLIAVAV MMAR_0094|M.marinum_M YTMYRGVAHVILGSGLTIAGAMYCLTFTRMPYFQSMGIPCAAGMLVAVVA MAB_4116c|M.abscessus_ATCC_199 YTAYKGVAKVVLASGLTIAGAIACLHFTRLPYFKPLGIPGAVGILVAVAV MSMEG_0381|M.smegmatis_MC2_155 YTSFAGVAKVVLASGATIAGAIACLSFTRLPYFQPLGIPGAVGIGVAVAV TH_3056|M.thermoresistible__bu FTTYRSVAKVVLASGLTIAGAIACLSFTRLPHFQPLGIPGAVGLLVAVAV MAV_3249|M.avium_104 FTTYRSVAPVVLGSGLTIAGAMLCLSFTRMPIFQTMGLPCSVGMLISVFI Mvan_3833|M.vanbaalenii_PYR-1 YEMFGGTAHVVLGSGLTIAGAMYCLSFARMPYFQSMGVPCAVGILAGVAV Mflv_4418|M.gilvum_PYR-GCK YTMFRGTAHVVLGSGLTIAGAMLCLSFTRLPYFQTMGVPCAVGTFVAVIA MUL_0757|M.ulcerans_Agy99 YTMFGGTAHVVLGSGLTIAGATFCLSFTRLPYFQTLGVPLAIGMVIVVAT : : .. *:*.** **:** ** *:*:* *:.:*:* : * * Mb0458c|M.bovis_AF2122/97 ALTLGPAVLHVGSRFG-LFDPKRLLKVRGWRRVGTVVVRWPLPVLVATCA Rv0450c|M.tuberculosis_H37Rv ALTLGPAVLHVGSRFG-LFDPKRLLKVRGWRRVGTVVVRWPLPVLVATCA MLBr_02378|M.leprae_Br4923 ALTLGPAVLTVGSRFG-LFEPKRLIKVRGWRRIGTVVVRWPLPILITTCA MMAR_0094|M.marinum_M ALTMGPAVLALGSRFG-LFDPKRKIKTRGWRRIGTAVVRWPAPILTATCA MAB_4116c|M.abscessus_ATCC_199 ALTLVPACIAAGSRFG-LFDPKRQVTTRRWRRVGTAIVRWPGPILAATVA MSMEG_0381|M.smegmatis_MC2_155 ALTLVPACIAATNRFG-WFDPRRLVTTRRWRRIGTAVVRWPAPILIATIA TH_3056|M.thermoresistible__bu ALTLVPATIALGSRFG-LFEPKRRVMTHRWRRIGTAVVRWPVPILTAAVA MAV_3249|M.avium_104 ALTLVPAVLTVGGGFG-LFDPKRAIGFGRWRRIGTAIVRWPAPILTATIA Mvan_3833|M.vanbaalenii_PYR-1 ALTLGPAIVTVGSRFG-LLEPKRAMRIRAWRRVGATVVRWPGPILVASLA Mflv_4418|M.gilvum_PYR-GCK ALTLGPAVIVIGSRFG-LFDPKRAISSRGWRRIGVSVVRWPGPVLAATLA MUL_0757|M.ulcerans_Agy99 ALTLGPALIAVMSRFGKLLEPKRMARVRGWRKIGAAIVRWPGPILIGAVA ***: ** : . ** ::*:* **::*. :**** *:* : * Mb0458c|M.bovis_AF2122/97 IALVGLLALPGYKTSYNDRDYLPDFIPANQGYAAADRHFSQARM-KPEIL Rv0450c|M.tuberculosis_H37Rv IALVGLLALPGYKTSYNDRDYLPDFIPANQGYAAADRHFSQARM-KPEIL MLBr_02378|M.leprae_Br4923 IAMVGLLALPGYRTNYKDRAYLPASIPANQGFAAADRHFPQARM-KPEIL MMAR_0094|M.marinum_M VSLVGLIALPGYQTNYDDQTYVPENIPANAGYAAANRHFPPSRM-KPDVL MAB_4116c|M.abscessus_ATCC_199 VALIGLLTLPGYNPSYTDAKFIPQDIPATQGLVAASRHFPESKMSTPDIL MSMEG_0381|M.smegmatis_MC2_155 VAVIGLLTLPGYNPSYSDQKYIPQDIPANQGFAAAARHFPESKMTTPDIL TH_3056|M.thermoresistible__bu LSLVGLLTLPGYNPSYSDQEFIPDDIPASEGYKAAARHFPASAMSVPDVV MAV_3249|M.avium_104 VALVGLVTLPGYKTSYNNRLYMPDSVPANVGYAAADRHFTQSRM-MPELL Mvan_3833|M.vanbaalenii_PYR-1 LALIGLAALPGYKTSYDDTRYIPESIPANAGLQAATKYFSLSRM-SPEVL Mflv_4418|M.gilvum_PYR-GCK LALVGLVTLPGYKTNYDARDYLPEDIPANVGYAVADQHFGSARM-NPELL MUL_0757|M.ulcerans_Agy99 LALVGLLTLPGYKTNYNDRNYLPADLPANEGYSAAERHFSQARM-NPEVL ::::** :****...* ::* :**. * .* ::* : * *::: Mb0458c|M.bovis_AF2122/97 MIESDHDMRNPADFLVLDKLAKGIFRVPGISRVQAITRPEGTTMDHTSIP Rv0450c|M.tuberculosis_H37Rv MIESDHDMRNPADFLVLDKLAKGIFRVPGISRVQAITRPEGTTMDHTSIP MLBr_02378|M.leprae_Br4923 MIESDHDMRNPADFLILDKLARGIFRVPGISRVQAITRPDGTAMDHTSIP MMAR_0094|M.marinum_M LIVADHDMRNSADFLVLDKLAKGIFHVPGISRVQAITRPKGTPIEHTSIP MAB_4116c|M.abscessus_ATCC_199 LIEANHDMRNSADLLVLNRLAKAVFAVPGIANVQSITRPEGTQIEHSSVP MSMEG_0381|M.smegmatis_MC2_155 LVEADHDMRNSADLLVLNKLAKAVFAVPGVSNVQAITRPEGTPIEHTSIP TH_3056|M.thermoresistible__bu LIEADRDMRNPADLLVLNKVAKKIFEVPGVANVQSVTRPEGRQIEHTTIP MAV_3249|M.avium_104 MIESDHDMRNPADFLVLHRLAKGVFGVHGISRVQGITRPEGTPIQHTSIP Mvan_3833|M.vanbaalenii_PYR-1 IVEADRDLRNSSDFLILDRLAKRVFNVEGVARVQAPSRPDGAPIAHTSIP Mflv_4418|M.gilvum_PYR-GCK MVESDHDLRNPADFLVIDKIAKSVFRVPGVARVQTITRPDGKPIKHTTIP MUL_0757|M.ulcerans_Agy99 MVESDHDMRNSSDFLVINKIAKAIFGVEGISRVQAITRPDGKPIEHTSIP :: :::*:**.:*:*::.::*: :* * *::.** :**.* : *:::* Mb0458c|M.bovis_AF2122/97 FQISMQNAGQLQTIKYQRDRANDMLKQADEMATTIAVLTRMHSLMAEMAS Rv0450c|M.tuberculosis_H37Rv FQISMQNAGQLQTIKYQRDRANDMLKQADEMATTIAVLTRMHSLMAEMAS MLBr_02378|M.leprae_Br4923 FQISMQNAGQVQTMKYQKDRMNDLLRQAENMAETIASMRRMHQLMALLTE MMAR_0094|M.marinum_M FQISMQNAGQLQNMKYQRDRMNDMLTQADQLTSTIALMKRTYDLMLQMSK MAB_4116c|M.abscessus_ATCC_199 FMLSMSNASQRLSLPFQRARMDDMLKQADDMSKTIALMQRMSDLMNQMVD MSMEG_0381|M.smegmatis_MC2_155 FMLSMSNASQRLSLPFQQQRMEDLLKQADELTKNIALMKHMYALMQEMVA TH_3056|M.thermoresistible__bu FMLSMSQASQRLALPFQRARMDDMLKQADELTETIALMRRMQSLMEKMVA MAV_3249|M.avium_104 FLLSMQQATMHQDIQYMKARMDDMLVQADLMRKQIEIMRHIYELQKRLTD Mvan_3833|M.vanbaalenii_PYR-1 FLISMQGVGQQQNMKLMKDRIADMRVQADDIGETIATMKTMYGLMTKFSN Mflv_4418|M.gilvum_PYR-GCK FQMSMQGTTQRLNEKYLQDRMADMLVQADAMQTNVDTMTRMQSLMGQMSA MUL_0757|M.ulcerans_Agy99 FLISMQGTSQKLTEKYNQDLTTSMLQQVNDIQTNIDQMERMHDLTQQMAD * :**. . : .: *.: : : : * : Mb0458c|M.bovis_AF2122/97 TTHRMVGDTEEMKEITEELRDHVADFDDFWRPIRSYFYWEKHCYGIPICW Rv0450c|M.tuberculosis_H37Rv TTHRMVGDTEEMKEITEELRDHVADFDDFWRPIRSYFYWEKHCYGIPICW MLBr_02378|M.leprae_Br4923 NTHHILNDTVEMQKTTSKLRDEIANFDDFWRPIRSYFYWERHCFNIPICW MMAR_0094|M.marinum_M TTHRMVGDTLEMKSVTDELRDHIADFEDTWRPIRSYFYWEKHCADIPICW MAB_4116c|M.abscessus_ATCC_199 TTHRMVSTTKDLQQDMRTLRDHIEDFEDFWRPIRNYFYWDKHCFDIPICW MSMEG_0381|M.smegmatis_MC2_155 TTHSTVETTHEVQQTTKDLRDSIEDFQDFWRPIRNYLYWEPHCYDIPLCW TH_3056|M.thermoresistible__bu TTHSMVGTTHELLDTTRDLRDHIADFDDFFRPIRNYFHWEPHCYNIPICW MAV_3249|M.avium_104 ITHDSIVKTKEMAAVLWELRDKMSDFEDFWRPLRSYFYWEKHCYDIPICW Mvan_3833|M.vanbaalenii_PYR-1 ITTVMIDDMTEMRDTVHQIRDMVATFDDQFRPIRNYFYWEPHCYNIPLCW Mflv_4418|M.gilvum_PYR-GCK TTHEMVLKTKKTEIDIIEVRDNLADFDDFFRPVRNYFYWEPHCYDIPVCW MUL_0757|M.ulcerans_Agy99 VTHQMVIQMKGMVVDVEELRNHIADFDDFFRPIRSYFYWEKHCFDIPVCW * : :*: : *:* :**:*.*::*: ** .**:** Mb0458c|M.bovis_AF2122/97 SFRSIFDALDGIDKLSEQIGVLLGDLREMDRLMPQMVAQIPPQIEAMENM Rv0450c|M.tuberculosis_H37Rv SFRSIFDALDGIDKLSEQIGVLLGDLREMDRLMPQMVAQIPPQIEAMENM MLBr_02378|M.leprae_Br4923 SFRSIFDALDGVDQIDERLNSIVGDIKNMDLLMPQMLEQFPPMIESMESM MMAR_0094|M.marinum_M SLRSIFDALDGVDQVSEQLTTLTGDLTDMDRILPQVVATFPQMIQNMEGM MAB_4116c|M.abscessus_ATCC_199 SIRSIFDALDGVDQVTDKMQTLVGDLDELDKLMPQLLEQFPIMIETMKST MSMEG_0381|M.smegmatis_MC2_155 SIRSLFDGLDGINEVTDKMGDLVEDLDHLDTLMPQMLLQFPPMIAMLENS TH_3056|M.thermoresistible__bu SIRSIFDALDGINEMTEKMEELVEDMDRLDALMPQMLVQFPQMIETMESS MAV_3249|M.avium_104 SLRNIFETLDGVDTLSDKMTYLLQDLDHMDRLMPQLLEQYPPMIAMSEDM Mvan_3833|M.vanbaalenii_PYR-1 SFRSLFDSMDGISVMTDTFDKAVANMDEMKALLPQMLATFPPMIETMESM Mflv_4418|M.gilvum_PYR-GCK TMRSVFDTLDGINPLTDDISELIPDLERLDELMPQLIALLPSQIETMRSM MUL_0757|M.ulcerans_Agy99 SLRSVFDTLDGVDLMTEDINNLLPLMERLDTLMPQMTAMMPEMIQTMKSM ::*.:*: :**:. : : : : :. ::**: * * .. Mb0458c|M.bovis_AF2122/97 RTMILTMHSTMTGIFDQMLEMSDNATAMGKAFDAAKNDDSFYLPPEVFKN Rv0450c|M.tuberculosis_H37Rv RTMILTMHSTMTGIFDQMLEMSDNATAMGKAFDAAKNDDSFYLPPEVFKN MLBr_02378|M.leprae_Br4923 RTIMLTMHSTMSGIFDQMNELSDNANTMGKAFDTAKNDDSFYLPPEVFKN MMAR_0094|M.marinum_M RTLILTMHSTMSGIYDQMDELSKNSTAMGQAFDAAKNDDSFYLPPEVFNN MAB_4116c|M.abscessus_ATCC_199 RESMLTMHSTMSGIFAQMDESTENSTAMGKAFDASKNDDSFYLPPDVLKN MSMEG_0381|M.smegmatis_MC2_155 RSMILTMHSTMSGIFSQMDDSTDNATAMGKAFDAARNDDSFYLPPDILEN TH_3056|M.thermoresistible__bu RTMILTMHATMSGIFDQMESSSENATAMGKAFDASHNDDSFYLPPEALEN MAV_3249|M.avium_104 LRMMLTNHSTMSGIIGQMDSNNKDATAMGEAFDASKNDDSFYLPPDIFDN Mvan_3833|M.vanbaalenii_PYR-1 RQMMLTTYATMGGFYDQMDELTRDSTEMGKAFDAAKNDDSFYLPPEVFEN Mflv_4418|M.gilvum_PYR-GCK QAMMLRQYQTQKGQLDQNAAMSEDADAMGEAFDDSMNDDSFYLPPEAFDN MUL_0757|M.ulcerans_Agy99 KAQMLSMHSTQQGLQDQMAAMQEDSSAMGEAFDSSRNDDSFYLPPEVFNN :* : * * * :: **:*** : *********: :.* Mb0458c|M.bovis_AF2122/97 KDFQRAMKSFLSSDGHAARFIILHRGDPQSPEGIKSIDAIRTAAEESLKG Rv0450c|M.tuberculosis_H37Rv KDFQRAMKSFLSSDGHAARFIILHRGDPQSPEGIKSIDAIRTAAEESLKG MLBr_02378|M.leprae_Br4923 TDFKRAMKSFLSSDGHAARFIILHRGDPASVAGIASINAIRTAAEEALKG MMAR_0094|M.marinum_M PDFKRGMKMFLSQDGKAARLFIFHRGNAAGYEGISSISAINIAAAEALKG MAB_4116c|M.abscessus_ATCC_199 KDFQRVMKIFMSPDGKSSRMLISQRGDPATPEGISRVEPIKTAAEEALKG MSMEG_0381|M.smegmatis_MC2_155 EDFKRVMKIFMSPDGKAARMLITQRGDPATPEGIALVEPIRVAAEEALKG TH_3056|M.thermoresistible__bu KDFQRVMEIFLSPDGKAARMLVTQRGDPATPEGMALVEPIYIAAEEALKG MAV_3249|M.avium_104 ADFKKAMSQFLSPDGKAARFIISHRGDPATSEALNRIDKIRSAAEEALKN Mvan_3833|M.vanbaalenii_PYR-1 EDFKRAMESFFSPDGKTVRMLIAHRGNPTTDEALQRVEPIKIAAIEALKG Mflv_4418|M.gilvum_PYR-GCK DDFKRGMENFISPDGRSVRFIISHEGDPATVEGISEVVPIKTAAKEAIKG MUL_0757|M.ulcerans_Agy99 PDFKRGLEQFLSPDGHAVRFIISHEGDPMSQAGINHIDKIKTAAKEAIKG **:: :. *:* **:: *::: :.*:. .: : * ** *::*. Mb0458c|M.bovis_AF2122/97 TPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAISSLCLIFIIMLIITRAF Rv0450c|M.tuberculosis_H37Rv TPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAISSLCLIFIIMLIITRAF MLBr_02378|M.leprae_Br4923 TPLEDTKIYLAGTAAVFKDIDEGANWDLVIAGISSLCLIFIIMLIITRAF MMAR_0094|M.marinum_M TPLEDAQIYLTGTAAVYKDIADGSKYDLIIAGLSSLCLIFIIMLLITRGF MAB_4116c|M.abscessus_ATCC_199 TPLEHAKLSLAGTAAGVSELVEGSKYDLLIAGVAALCLIFIIMLLMTRSL MSMEG_0381|M.smegmatis_MC2_155 TPLESAELHLAGTAAGVKDLVDGSKIDLLIAGVAALCLIFIIMLIMTRSF TH_3056|M.thermoresistible__bu TPLESSRIYLAGSAAGVKDLVEGAKYDLMIAAISAVCLIFMIMVFMTRSV MAV_3249|M.avium_104 TPLENAKIYLAGTASTFKDFRDGSTYDLFIAGVGALCLIFIIMLILTRSF Mvan_3833|M.vanbaalenii_PYR-1 TPLENAQIQLGGTAATFKDMSDGSRYDLLIAVISALCLVLMIMLVLTRSL Mflv_4418|M.gilvum_PYR-GCK TPLEGSTVYLAGTAATYKDMSDGAFYDLLIAGIAAVTLIFVIMLVITRSV MUL_0757|M.ulcerans_Agy99 TPLEGSTIYLGGTVAMFKDLSDGNTFDLMIAGISALCLIFIIMLIITRSV **** : : * *:.: :: :* **.** :.:: *:::**:.:**.. Mb0458c|M.bovis_AF2122/97 IAAAVIVGTVALSLGASFGLSVLLWQHILAIHLHWLVLAMSVIVLLAVGS Rv0450c|M.tuberculosis_H37Rv IAAAVIVGTVALSLGASFGLSVLLWQHILAIHLHWLVLAMSVIVLLAVGS MLBr_02378|M.leprae_Br4923 VAAAVIVGTVALSLGASFGLSVLLWQHILGIELHYLVLAMSVIVLLAVGS MMAR_0094|M.marinum_M VAALVIVGTVALSLGVSFGLSVLLWQHLLRIELHWLVLAMSVIVLLAVGS MAB_4116c|M.abscessus_ATCC_199 VAALVIVGTVALSLGASFGLSVLVWQHICGIQINWVVLAMSVIVLLAVGS MSMEG_0381|M.smegmatis_MC2_155 IAALVIVGTVAMSLGASFGLSVLVWQHLLGIQINWVVLAMSVIVLLAVGS TH_3056|M.thermoresistible__bu IAALVIVGTVVLSLGASFGMSVLLWQHLLGIQLHWVVLAMSVIVLLAVGS MAV_3249|M.avium_104 IAALVIVGTVTLSLGASFGLSVLIWQYIFGIQLYWMVLPMSVIVLLAVGS Mvan_3833|M.vanbaalenii_PYR-1 VAALVIVGTVTLSLGASFGISILIWQHIVGIELHWMVLALSIIALIAVGS Mflv_4418|M.gilvum_PYR-GCK VAAAVIVGTVLLSLGASFGLSVLLWQHIIGLALHWMVLPMAVILLLAVGS MUL_0757|M.ulcerans_Agy99 VAAAVIVGTVVLSLGASFGLSVLIWQHVLGIELHWLVLAMAVIILLAVGA :** ****** :***.***:*:*:**:: : : ::**.:::* *:***: Mb0458c|M.bovis_AF2122/97 DYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVVTNAGLVFAVTMASMAVS Rv0450c|M.tuberculosis_H37Rv DYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVVTNAGLVFAVTMASMAVS MLBr_02378|M.leprae_Br4923 DYNLLLVSRFKQEIQAGLKTGIIRSMGGTGKVVTNAGLVFAFTMASMVVS MMAR_0094|M.marinum_M DYNLLLVSRLKEEVGAGIKTGIIRAMGGTGKVVTSAGLVFALTMASMAVS MAB_4116c|M.abscessus_ATCC_199 DYNLLLVSRMKEELGAGLKTGIIRAMGGTGKVVTAAGLVFAATMGSMIVS MSMEG_0381|M.smegmatis_MC2_155 DYNLLLVSRMKEEIGAGLNTGIIRAMGGTGKVVTAAGLVFAATMASMIVS TH_3056|M.thermoresistible__bu DYNLMLVSRMKEEIGAGLNTGIIRAMGGTGRVVTMAGLVFAATMASMIVS MAV_3249|M.avium_104 DYNLLLVSRMKEEISAGINTGIIRAMGGTGKVVTNAGLVFAFTMASMVVS Mvan_3833|M.vanbaalenii_PYR-1 DYNLLLVSRFKEEIPAGIKTGIIRAIGGTGSVVTVAGVVFALTMASMVVS Mflv_4418|M.gilvum_PYR-GCK DYNLLLVSRFKEELSGGLKTGIIRAMAGTGSVVTSAGLVFAFTMASFAFS MUL_0757|M.ulcerans_Agy99 DYNLLLVARLKEEIHAGINTGIIRAMGGSGSVVTAAGLVFAFTMMSFAVS ****:**:*:*:*: .*::*****::.*:* *** **:*** ** *: .* Mb0458c|M.bovis_AF2122/97 DLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAALLGRWFWWPLRVRSRPA Rv0450c|M.tuberculosis_H37Rv DLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAALLGRWFWWPLRVRSRPA MLBr_02378|M.leprae_Br4923 DLRVIGQVGTTIGLGLLFDTLIVRSFMMPSIAALLGRWFWWPQQGRTRPL MMAR_0094|M.marinum_M DLIVIGQIGTTIGLGLLFDTLIVRSLMTPSIAALLGRWFWWPLNIRSRPP MAB_4116c|M.abscessus_ATCC_199 DLLTIGQVGTTIGLGLLFDTLIVRAFMTPAIAALLGRWFWWPLQVSPRPV MSMEG_0381|M.smegmatis_MC2_155 DLLTIGQVGTTIGLGLLFDTLVVRAFMTPSIAALLGRWFWWPQRVRQRPA TH_3056|M.thermoresistible__bu DLLMIGQVGTTIALGLLFDTMVVRAFMTPSVAAILGRWFWWPQRVRTRPA MAV_3249|M.avium_104 DLRIIGQVGTTIGLGLMFDTLIVRSFMTPTIAALLGRWFWWPQLVRRRPA Mvan_3833|M.vanbaalenii_PYR-1 DLRVMAQVGTTIGLGLLFDTFIVRAFMMPAIATLLGRWFWWPLVVRSRPL Mflv_4418|M.gilvum_PYR-GCK DLKVMAQVGTTIALGLLFDTLIVRSFMTPAVAALLGRWFWWPQKFRSAAS MUL_0757|M.ulcerans_Agy99 ELTVMAQVGTTIGMGLLFDTLIVRSFMTPSIAALLGKWFWWPQVVRQRPA :* :.*:****.:**:***::**::* *::*::**:***** . Mb0458c|M.bovis_AF2122/97 RTPTVPSETQPAGRPLAMSSDRLG------------- Rv0450c|M.tuberculosis_H37Rv RTPTVPSETQPAGRPLAMSSDRLG------------- MLBr_02378|M.leprae_Br4923 LTVAAPVGLPPD-RSLVYSD----------------- MMAR_0094|M.marinum_M RLTRQRPLPSVSQEPAAARV----------------- MAB_4116c|M.abscessus_ATCC_199 GAVRGWRGPR-LVRSVLQRN----------------- MSMEG_0381|M.smegmatis_MC2_155 SAMLRSVGPRPLVRSLLLRD----------------- TH_3056|M.thermoresistible__bu SAMLRPVGPRPLVRSLLLRD----------------- MAV_3249|M.avium_104 SQLLRSEGTRRSVRVLLHQNDDADADTAEIPVPRPTA Mvan_3833|M.vanbaalenii_PYR-1 RLPPRT------------------------------- Mflv_4418|M.gilvum_PYR-GCK ERRLARIGVQPATAGR--------------------- MUL_0757|M.ulcerans_Agy99 PQPWPTPAPTPPPATTSV-------------------