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SGKYLNNTDIEPSILARSIYKFAVPIALFWLAVCAIIAAFVPSLESVGENRSVSLTPRDAPAMQAIHRIG AVFKESDSDSIVTIVLEGDQPLGTEAHKYYDDLVRRLRGDTRHVQHVQDFWGDPLTASGSQSADDKAAYV QLNLAGNQGEPLGNESVEAVRSIVDGAKPPPGIAVYVTGTAALVADMQHSGDRSLARITVTTAAVIFIML LLVYRSPLTVVLLLLTVGAEFTVARGVVALLGQVGAIALSTFAVSLLTSLAIAAGTDYGIFIIGRYQEAR QAGEDRETAFYTMYRGVAHVIAGSGLTIAGATSCLSLARLPYFRTLGIPCAVGMLLAVVVALTLGPAVLA IGSRFGVFDPKRMIKIRGWRRIGTVVVRWPGPVLAATIAIALIGLLALPAYTTSYNNRDYTPGFTPANQG FAAADRHFSQSRMKPEALLIESDHDLRNPADFLVLDKVAKEIFRIPGISRVQGITRPEGKPMDHTSIPFQ ISMQNASQMQNLNYQRDRMDDLLRQADAIGKSITVMKRMYDLMMQMSDTMHQTVIDTGQIKDVTDELRDH IADFDDFWRPIRSYFYWDKHCNGVPMCWSLRSIFDALDGVDKISDELTDLLGDVKTMDRLMPLTAAQIPP QIEALETVRDIVLTMHSTMIGIYDQMDELSANSTAMGKAFDTANNDDSFYLPPEVFTNANFKRIMKLFLS PDGHAARFIILHRGDPDRPEGIARIDLIRTAAEESLKGSPLEDSRIYLTGTGAVSKDLSEGAKWDLLIAG IASLCLIFIIMLILTRALIAATVIVGTVALSLGASFGLSVLVWQHIFGIKLHWLVLPMSVIVLLAVGSDY NLLLVSRFKQEIGAGLNTGIIRAIGGTGKVVTNAGLVFAITMASMIVSDLRIIGQVGTTISLGLLFDTLI VRAFMTPSIAALLGRWFWWPLQVRTRPTRPTAVKPRRPDPPDHLPSVGERHQTRRLRALSTETLSPG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1877 | mmpL5_1 | - | 100% (978) | transmembrane transport protein, MmpL5_1 |
| M. marinum M | MMAR_0771 | mmpL5_2 | 0.0 | 72.54% (965) | transmembrane transport protein MmpL5_2 |
| M. marinum M | MMAR_0255 | mmpL5_4 | 0.0 | 69.64% (942) | transmembrane transport protein, MmpL5_4 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0458c | mmpL4 | 0.0 | 74.84% (954) | transmembrane transport protein MmpL4 |
| M. gilvum PYR-GCK | Mflv_4418 | - | 0.0 | 60.63% (927) | transport protein |
| M. tuberculosis H37Rv | Rv0450c | mmpL4 | 0.0 | 74.95% (954) | transmembrane transport protein MmpL4 |
| M. leprae Br4923 | MLBr_02378 | - | 0.0 | 70.05% (945) | hypothetical protein MLBr_02378 |
| M. abscessus ATCC 19977 | MAB_2301 | - | 0.0 | 59.94% (971) | putative membrane protein, mmpL |
| M. avium 104 | MAV_3249 | - | 0.0 | 64.36% (912) | Mmp14A protein |
| M. smegmatis MC2 155 | MSMEG_0382 | - | 0.0 | 61.33% (944) | putative transport protein |
| M. thermoresistible (build 8) | TH_3056 | - | 0.0 | 59.07% (948) | PUTATIVE Mmp14a protein |
| M. ulcerans Agy99 | MUL_0757 | mmpL5 | 0.0 | 60.63% (945) | transmembrane transport protein, MmpL5 |
| M. vanbaalenii PYR-1 | Mvan_1936 | - | 0.0 | 60.47% (931) | transport protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0458c|M.bovis_AF2122/97 ----MSTKFANDSNTNARPEKPFIARMIHAFAVPIILGWLAVCVVVTVF-
Rv0450c|M.tuberculosis_H37Rv ----MSTKFANDSNTNARPEKPFIARMIHAFAVPIILGWLAVCVVVTVF-
MLBr_02378|M.leprae_Br4923 ----MTVKCANDLDTHTKP--PFVARMIHRFAVPIILVWLAIAVTVSVF-
MMAR_1877|M.marinum_M ----MSGKYLN--NTDIEP--SILARSIYKFAVPIALFWLAVCAIIAAF-
MAV_3249|M.avium_104 --------------------------------MFIILGWVALTLLVTFG-
MSMEG_0382|M.smegmatis_MC2_155 --------MSTEQSGTEKARRPFFARAVRTLSPFIIVGWLAVILVTTLAA
TH_3056|M.thermoresistible__bu --------MSVLDRVGVEPRRPRVASFIRRYSVLIILGWVALTVLATVA-
Mflv_4418|M.gilvum_PYR-GCK ---------------MADAGRSGIGRIIRVLAVPIVLGWVLLTVLTNVA-
Mvan_1936|M.vanbaalenii_PYR-1 ---------------MADAGRSGIGRIIHLLAVPIVLGWIALTVLTNVA-
MUL_0757|M.ulcerans_Agy99 MTATTTDTPTDVVPPAEHPPRPFIPRMIRTFAVPLILGWVLLIAVLNSV-
MAB_2301|M.abscessus_ATCC_1997 MSGSHAG--------RSAAEPTFLAKWIRRLSIPIVIGWLAIVFALNTF-
: : *: :
Mb0458c|M.bovis_AF2122/97 --------VPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKEGDSDSFA
Rv0450c|M.tuberculosis_H37Rv --------VPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKEGDSDSFA
MLBr_02378|M.leprae_Br4923 --------IPSLEDVGQERSVSLSPKDAPSYIAMQKMGQVFNEGNSDSVI
MMAR_1877|M.marinum_M --------VPSLESVGENRSVSLTPRDAPAMQAIHRIGAVFKESDSDSIV
MAV_3249|M.avium_104 --------VPRLEIVGQQHSVPLAPQDAPAVQAMQRMGRDFKESDSDSFA
MSMEG_0382|M.smegmatis_MC2_155 VGGDWSAAIPALERVGEKNSVSLMPQDAPSAKAMKHMGQKFEESDSDSFA
TH_3056|M.thermoresistible__bu --------VPPLEAVEREKSLSLIPYDAPAFAAMHRMGELFDEPDSESIA
Mflv_4418|M.gilvum_PYR-GCK --------VPSLEKVGEEHTVGMSAGDAPSMMSMKRVGANFEEFDSDSSA
Mvan_1936|M.vanbaalenii_PYR-1 --------VPSLEKVGEEHTVGMSANDAPSMMSMERVGANFDEFDSDSSA
MUL_0757|M.ulcerans_Agy99 --------VPQLEVVGQMQAVSMSPDAAPSMISMKHIGKVFREGDSDSAA
MAB_2301|M.abscessus_ATCC_1997 --------VPQLEQVGKEHTVSLSPQSAPSMQAMKHMGKMFKESDSDSVV
:* ** * . .:: : . **: :: ::* * * :*:*
Mb0458c|M.bovis_AF2122/97 MVIIEGNQPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDPLTAAGVQS
Rv0450c|M.tuberculosis_H37Rv MVIIEGNQPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDPLTAAGVQS
MLBr_02378|M.leprae_Br4923 MIVLEGDKPLGDDAHRFYDGLIRKLRADK-HVQSVQDFWGDPLTAPGAQS
MMAR_1877|M.marinum_M TIVLEGDQPLGTEAHKYYDDLVRRLRGDTRHVQHVQDFWGDPLTASGSQS
MAV_3249|M.avium_104 MLVLEGQQQLGDDAHAYYDKLVRELRNDTKHVEHVQDLWGDRLTQAGAQS
MSMEG_0382|M.smegmatis_MC2_155 MIVLEGQEPLGPDALDYYTGLISELRNDSKHVEHVQDLWGDRLTASSAQS
TH_3056|M.thermoresistible__bu IIVLEGQEPLGLEAHEYYDQLISQLREHPQYVQHIRDFWGDPLTAGAAQS
Mflv_4418|M.gilvum_PYR-GCK MVVLEGEQPLGDAAHRYYDQLIDELEADTANVQHIADFWGDPLTASGAQS
Mvan_1936|M.vanbaalenii_PYR-1 MVVLEGEQPLGDAAHRYYDELIGKLEADTANVQHVADFWGDPLTASGAQS
MUL_0757|M.ulcerans_Agy99 MIVLEGQEPLGAAAHKFYDKMITKLRADTKHVQSVQDFWGDPLTATGAQS
MAB_2301|M.abscessus_ATCC_1997 MIVLEGQERLGPGSHKFYDEMVARLRADTKHVQHVQDFWGDPLTEAGAQS
:::**:: ** : :* :: .*. . *: : *:*** ** . **
Mb0458c|M.bovis_AF2122/97 NDGKAAYVQLSLAGNQGTPLANESVEAVRSIVESTPA---------PPGI
Rv0450c|M.tuberculosis_H37Rv NDGKAAYVQLSLAGNQGTPLANESVEAVRSIVESTPA---------PPGI
MLBr_02378|M.leprae_Br4923 NDGKAAYVQLSLAGNQGELLAQESIDAVRKIVVQTPA---------PPGI
MMAR_1877|M.marinum_M ADDKAAYVQLNLAGNQGEPLGNESVEAVRSIVDGAKP---------PPGI
MAV_3249|M.avium_104 PDGKAVYVQLNLAGNQGTTLGQESVAAVRDVIARIPP---------PAGL
MSMEG_0382|M.smegmatis_MC2_155 ADGKAAYVQLNLAGNQGTPLGDESVAAVRDLVARTPA---------PEGV
TH_3056|M.thermoresistible__bu DDGKAAFVQVNLVGRFGQAKVNEAVRAVQEIVERTPA---------PEGV
Mflv_4418|M.gilvum_PYR-GCK TDGKAAYVQVYLQGNQGEPRANEAVAAVREIVDRTPA---------PPGI
Mvan_1936|M.vanbaalenii_PYR-1 TDGKAAYVQVYLQGNQGEPRANEAVAAVREIVDQTPA---------PPGL
MUL_0757|M.ulcerans_Agy99 GDGKAAYVQVKLAGNQGESLANESVEAVKTIVDSLQA---------PPGV
MAB_2301|M.abscessus_ATCC_1997 TDGKATYVQVNLAGNMGETLSNESTEAARNIVKQLEADWTKDGNKLPDGL
*.**.:**: * *. * :*: *.: :: . * *:
Mb0458c|M.bovis_AF2122/97 KAYVTGPSALAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSIITVVLL
Rv0450c|M.tuberculosis_H37Rv KAYVTGPSALAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSIITVVLL
MLBr_02378|M.leprae_Br4923 TAWVTGASALIADMHHSGDKSMIRITATSVIVILVTLLLVYRSFITVILL
MMAR_1877|M.marinum_M AVYVTGTAALVADMQHSGDRSLARITVTTAAVIFIMLLLVYRSPLTVVLL
MAV_3249|M.avium_104 KAYVTGPAALFSDMQLAGDRSILKMTLIGALIIFIVLLFVYRSVTTVVLL
MSMEG_0382|M.smegmatis_MC2_155 SVYVTGAAPLVSDMQHSGNRSILKITAVTVVIIFAMLLMVYRSVITVILL
TH_3056|M.thermoresistible__bu ETFVTGPAALGADAGDSGTATVILITLVTVAVIFLMLLFFFRSFLTVIVL
Mflv_4418|M.gilvum_PYR-GCK KAYVTGGAPLVADQHSAGDTSVLRVTLITIGVIAVMLLIVFRSVATMVLI
Mvan_1936|M.vanbaalenii_PYR-1 KAYVTGGAPLVADQHNAGDKSVFRVTLITIGVIAVMLLLVFRSVATMVLI
MUL_0757|M.ulcerans_Agy99 KVYVTGSAALVADQQLAGDRSLQLIEMVTFTVIIVMLLLVYRSIITAAIM
MAB_2301|M.abscessus_ATCC_1997 TVYVTGPGALQTDMNHAGDGSLQLITGLTFLVIVVMLLFFYRSIFTVIMV
.:*** ..* :* :* :: : :* **:.:** * ::
Mb0458c|M.bovis_AF2122/97 LITVGVELTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFII
Rv0450c|M.tuberculosis_H37Rv LITVGVELTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFII
MLBr_02378|M.leprae_Br4923 LFTVGIESAVARGVVALLGHTGLIGLSTFAVNLLTSLAIAAGTDYGIFIT
MMAR_1877|M.marinum_M LLTVGAEFTVARGVVALLGQVGAIALSTFAVSLLTSLAIAAGTDYGIFII
MAV_3249|M.avium_104 LLTVGIEVFAARGVIAFVANNNLMPLSTFAVNLLVALAMAAGTDYAIFFF
MSMEG_0382|M.smegmatis_MC2_155 LIMVGFEVAAARGIVAFLGANEVFVLSTFAVNMLVFLAIAAGTDYGIFFF
TH_3056|M.thermoresistible__bu LLTVAVELQVARGLVAYLGLQGWVGLTTYVVNLLVSVGIAAGTDYGIFFF
Mflv_4418|M.gilvum_PYR-GCK LFMVFAELGAARGIVAFLADAEIIGLSTFATSLLTLMVIAAGTDYAIFAI
Mvan_1936|M.vanbaalenii_PYR-1 LFMVFAELGAARGIVAFLANAEIIGLSTFATSLLTLMVIAAGTDYAIFAI
MUL_0757|M.ulcerans_Agy99 LTMVVLGLLATRGGVAFLGYHRIIGLSTFATNLLVVLAIAAATDYAIFLI
MAB_2301|M.abscessus_ATCC_1997 FMLVGIQLSAARGVIAFLGNTEIIGLSTFAVNLLVMLSIAAGTDYAIFLI
: * .:** :* :. . *:*:...:*. : :**.***.**
Mb0458c|M.bovis_AF2122/97 GRYQEARQAGEDKEAAYYTMYRGTAHVILGSGLTITGATFCLSFARMPYF
Rv0450c|M.tuberculosis_H37Rv GRYQEARQAGEDKEAAYYTMYRGTAHVILGSGLTIAGATFCLSFARMPYF
MLBr_02378|M.leprae_Br4923 GRYQEARQANENKEAAFYTMYRGTFHVILGSGLTISGATFCLSFARMPYF
MMAR_1877|M.marinum_M GRYQEARQAGEDRETAFYTMYRGVAHVIAGSGLTIAGATSCLSLARLPYF
MAV_3249|M.avium_104 GRYQEAREAGEDRATAYFTTYRSVAPVVLGSGLTIAGAMLCLSFTRMPIF
MSMEG_0382|M.smegmatis_MC2_155 GRYQEARAAGEDRETAYYSMYRGVTPVVMASGLTIAGAIFCLTFTRLPYF
TH_3056|M.thermoresistible__bu GRYQEAREAGEDRDSAYFTTYRSVAKVVLASGLTIAGAIACLSFTRLPHF
Mflv_4418|M.gilvum_PYR-GCK GRYQEARGAGEDRETAYYTMFRGTAHVVLGSGLTIAGAMLCLSFTRLPYF
Mvan_1936|M.vanbaalenii_PYR-1 GRYQEARGAGEDRETAYYTMFRGTAHVVLGSGLTIAGAMLCLSFTRLPYF
MUL_0757|M.ulcerans_Agy99 GRYQEARGLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFTRLPYF
MAB_2301|M.abscessus_ATCC_1997 GRYQEARAMGADKEAAYYEMFHGTAHVILGSGMTIAGAMYCLSFTRMPYF
******* . :: :*:: : .. *: .**:**:** **:::*:* *
Mb0458c|M.bovis_AF2122/97 QTLGIPCAVGMLVAVAVALTLGPAVLHVGSRFG-LFDPKRLLKVRGWRRV
Rv0450c|M.tuberculosis_H37Rv QTLGIPCAVGMLVAVAVALTLGPAVLHVGSRFG-LFDPKRLLKVRGWRRV
MLBr_02378|M.leprae_Br4923 QTLGVPCAVGMLIAVAVALTLGPAVLTVGSRFG-LFEPKRLIKVRGWRRI
MMAR_1877|M.marinum_M RTLGIPCAVGMLLAVVVALTLGPAVLAIGSRFG-VFDPKRMIKIRGWRRI
MAV_3249|M.avium_104 QTMGLPCSVGMLISVFIALTLVPAVLTVGGGFG-LFDPKRAIGFGRWRRI
MSMEG_0382|M.smegmatis_MC2_155 HTMGVPCAIGMLAAVAVAVTLVPAGVALAGRIG-WLEPKRKMRVRRWRGI
TH_3056|M.thermoresistible__bu QPLGIPGAVGLLVAVAVALTLVPATIALGSRFG-LFEPKRRVMTHRWRRI
Mflv_4418|M.gilvum_PYR-GCK QTMGVPCAVGTFVAVIAALTLGPAVIVIGSRFG-LFDPKRAISSRGWRRI
Mvan_1936|M.vanbaalenii_PYR-1 QTMGVPCAVGTFVAVMAALTLGPAVVAIGSRFG-LFDPKRAISSRGWRRI
MUL_0757|M.ulcerans_Agy99 QTLGVPLAIGMVIVVATALTLGPALIAVMSRFGKLLEPKRMARVRGWRKI
MAB_2301|M.abscessus_ATCC_1997 QTLGVPCSVGLLVGVLVSLTLGPALITIGSRFG-LFEPKRAMRIRSWRKI
:.:*:* ::* . * ::** ** : : . :* ::*** ** :
Mb0458c|M.bovis_AF2122/97 GTVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPANQGYA
Rv0450c|M.tuberculosis_H37Rv GTVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPANQGYA
MLBr_02378|M.leprae_Br4923 GTVVVRWPLPILITTCAIAMVGLLALPGYRTNYKDRAYLPASIPANQGFA
MMAR_1877|M.marinum_M GTVVVRWPGPVLAATIAIALIGLLALPAYTTSYNNRDYTPGFTPANQGFA
MAV_3249|M.avium_104 GTAIVRWPAPILTATIAVALVGLVTLPGYKTSYNNRLYMPDSVPANVGYA
MSMEG_0382|M.smegmatis_MC2_155 GTAIVRWPAPILVASLAVALVGLLALPGYETSYNDRDYIPADIPANAGFA
TH_3056|M.thermoresistible__bu GTAVVRWPVPILTAAVALSLVGLLTLPGYNPSYSDQEFIPDDIPASEGYK
Mflv_4418|M.gilvum_PYR-GCK GVSVVRWPGPVLAATLALALVGLVTLPGYKTNYDARDYLPEDIPANVGYA
Mvan_1936|M.vanbaalenii_PYR-1 GVSVVRWPGPVLAATLALALVGLVALPGYKTNYDSRDYLPEDVPANVGYA
MUL_0757|M.ulcerans_Agy99 GAAIVRWPGPILIGAVALALVGLLTLPGYKTNYNDRNYLPADLPANEGYS
MAB_2301|M.abscessus_ATCC_1997 GTTIVRWPGPVLAAAMAIAIIGLAALPGYRTSYDDKKYIPKDIPANAGFQ
*. :**** *:* : *::::** :**.* ..*. : : * **. *:
Mb0458c|M.bovis_AF2122/97 AADRHFSQARM-KPEILMIESDHDMRNPADFLVLDKLAKGIFRVPGISRV
Rv0450c|M.tuberculosis_H37Rv AADRHFSQARM-KPEILMIESDHDMRNPADFLVLDKLAKGIFRVPGISRV
MLBr_02378|M.leprae_Br4923 AADRHFPQARM-KPEILMIESDHDMRNPADFLILDKLARGIFRVPGISRV
MMAR_1877|M.marinum_M AADRHFSQSRM-KPEALLIESDHDLRNPADFLVLDKVAKEIFRIPGISRV
MAV_3249|M.avium_104 AADRHFTQSRM-MPELLMIESDHDMRNPADFLVLHRLAKGVFGVHGISRV
MSMEG_0382|M.smegmatis_MC2_155 AADRHFSQARM-TPDILMVESDHDMRNPTDFLVLNKIAKAIFKVRGVSRV
TH_3056|M.thermoresistible__bu AAARHFPASAMSVPDVVLIEADRDMRNPADLLVLNKVAKKIFEVPGVANV
Mflv_4418|M.gilvum_PYR-GCK VADQHFGSARM-NPELLMVESDHDLRNPADFLVIDKIAKSVFRVPGVARV
Mvan_1936|M.vanbaalenii_PYR-1 VADRHFGSARM-NPELLMVESDHDLRNPADFLVIDKIAKAIFRVPGVARV
MUL_0757|M.ulcerans_Agy99 AAERHFSQARM-NPEVLMVESDHDMRNSSDFLVINKIAKAIFGVEGISRV
MAB_2301|M.abscessus_ATCC_1997 AADRHFSQARM-NPEMLLIESDHDMRNSADFLVIDKIAKAVFRVPGIARV
.* :** : * *: :::*:*:*:**.:*:*::.::*: :* : *::.*
Mb0458c|M.bovis_AF2122/97 QAITRPEGTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQADEMAT
Rv0450c|M.tuberculosis_H37Rv QAITRPEGTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQADEMAT
MLBr_02378|M.leprae_Br4923 QAITRPDGTAMDHTSIPFQISMQNAGQVQTMKYQKDRMNDLLRQAENMAE
MMAR_1877|M.marinum_M QGITRPEGKPMDHTSIPFQISMQNASQMQNLNYQRDRMDDLLRQADAIGK
MAV_3249|M.avium_104 QGITRPEGTPIQHTSIPFLLSMQQATMHQDIQYMKARMDDMLVQADLMRK
MSMEG_0382|M.smegmatis_MC2_155 QGITRPEGTPIERTSIPFLLSLQSAGQVQATNFQKQRIGDMLKQVDDMNM
TH_3056|M.thermoresistible__bu QSVTRPEGRQIEHTTIPFMLSMSQASQRLALPFQRARMDDMLKQADELTE
Mflv_4418|M.gilvum_PYR-GCK QTITRPDGKPIKHTTIPFQMSMQGTTQRLNEKYLQDRMADMLVQADAMQT
Mvan_1936|M.vanbaalenii_PYR-1 QTITRPDGKPIKHTTIPFQMSMRSTTSRLNEKYMQDRMADMLVQADAMQT
MUL_0757|M.ulcerans_Agy99 QAITRPDGKPIEHTSIPFLISMQGTSQKLTEKYNQDLTTSMLQQVNDIQT
MAB_2301|M.abscessus_ATCC_1997 QAITRPQGTPIEHSSIPFLISMQSVGQRQNMKLMKDRMADMKVQADKMGE
* :***:* :.:::*** :*: . : .: *.: :
Mb0458c|M.bovis_AF2122/97 TIAVLTRMHSLMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDFWRPI
Rv0450c|M.tuberculosis_H37Rv TIAVLTRMHSLMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDFWRPI
MLBr_02378|M.leprae_Br4923 TIASMRRMHQLMALLTENTHHILNDTVEMQKTTSKLRDEIANFDDFWRPI
MMAR_1877|M.marinum_M SITVMKRMYDLMMQMSDTMHQTVIDTGQIKDVTDELRDHIADFDDFWRPI
MAV_3249|M.avium_104 QIEIMRHIYELQKRLTDITHDSIVKTKEMAAVLWELRDKMSDFEDFWRPL
MSMEG_0382|M.smegmatis_MC2_155 MIGVMKTTYGVLQELAATTHSLNGSTHELRDVARDLRGSIAIFDDLLRPI
TH_3056|M.thermoresistible__bu TIALMRRMQSLMEKMVATTHSMVGTTHELLDTTRDLRDHIADFDDFFRPI
Mflv_4418|M.gilvum_PYR-GCK NVDTMTRMQSLMGQMSATTHEMVLKTKKTEIDIIEVRDNLADFDDFFRPV
Mvan_1936|M.vanbaalenii_PYR-1 NVDTMTKMQSLMTQMSAATHDMVTKTKKTAVDIVEVRDYLANLDDFVRPV
MUL_0757|M.ulcerans_Agy99 NIDQMERMHDLTQQMADVTHQMVIQMKGMVVDVEELRNHIADFDDFFRPI
MAB_2301|M.abscessus_ATCC_1997 NVVIMKRTLANMTTMAGITHSLVGDMHTLQGTIHEMRDSISNFDDWFRPI
: : : * .:*. :: ::* **:
Mb0458c|M.bovis_AF2122/97 RSYFYWEKHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREMDRLM
Rv0450c|M.tuberculosis_H37Rv RSYFYWEKHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREMDRLM
MLBr_02378|M.leprae_Br4923 RSYFYWERHCFNIPICWSFRSIFDALDGVDQIDERLNSIVGDIKNMDLLM
MMAR_1877|M.marinum_M RSYFYWDKHCNGVPMCWSLRSIFDALDGVDKISDELTDLLGDVKTMDRLM
MAV_3249|M.avium_104 RSYFYWEKHCYDIPICWSLRNIFETLDGVDTLSDKMTYLLQDLDHMDRLM
MSMEG_0382|M.smegmatis_MC2_155 RNYFYWEPHCYNIPICWSLRSIFDAMDGVDRLNDELQVLVDNMDRLDALV
TH_3056|M.thermoresistible__bu RNYFHWEPHCYNIPICWSIRSIFDALDGINEMTEKMEELVEDMDRLDALM
Mflv_4418|M.gilvum_PYR-GCK RNYFYWEPHCYDIPVCWTMRSVFDTLDGINPLTDDISELIPDLERLDELM
Mvan_1936|M.vanbaalenii_PYR-1 RNYFYWEPHCYNIPVCATMRSVFDTLDGINPLTDDIQELIPDLERLDALM
MUL_0757|M.ulcerans_Agy99 RSYFYWEKHCFDIPVCWSLRSVFDTLDGVDLMTEDINNLLPLMERLDTLM
MAB_2301|M.abscessus_ATCC_1997 RNYLYWEKHCFDIPMCWAMRSIFDTLDKIDEMTETMDGMVVNMERMDTLM
*.*::*: ** .:*:* ::*.:*:::* :: : : : :: : :* *:
Mb0458c|M.bovis_AF2122/97 PQMVAQIPPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMGKAFD
Rv0450c|M.tuberculosis_H37Rv PQMVAQIPPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMGKAFD
MLBr_02378|M.leprae_Br4923 PQMLEQFPPMIESMESMRTIMLTMHSTMSGIFDQMNELSDNANTMGKAFD
MMAR_1877|M.marinum_M PLTAAQIPPQIEALETVRDIVLTMHSTMIGIYDQMDELSANSTAMGKAFD
MAV_3249|M.avium_104 PQLLEQYPPMIAMSEDMLRMMLTNHSTMSGIIGQMDSNNKDATAMGEAFD
MSMEG_0382|M.smegmatis_MC2_155 PELVAQFPEYIASMETFRELTLTSYSTFSGLLQQMDEQTEDVTAMGQAFD
TH_3056|M.thermoresistible__bu PQMLVQFPQMIETMESSRTMILTMHATMSGIFDQMESSSENATAMGKAFD
Mflv_4418|M.gilvum_PYR-GCK PQLIALLPSQIETMRSMQAMMLRQYQTQKGQLDQNAAMSEDADAMGEAFD
Mvan_1936|M.vanbaalenii_PYR-1 PQLIALLPSQIESMRNMQSMMLTMYQSQKGLQDQMASQSEDADAMGEAFD
MUL_0757|M.ulcerans_Agy99 PQMTAMMPEMIQTMKSMKAQMLSMHSTQQGLQDQMAAMQEDSSAMGEAFD
MAB_2301|M.abscessus_ATCC_1997 PKMVSDMSAMIPIMEDMQRMMLTQHSTMSGFYNQMDEMSQNSTAMGKAFD
* . * . * : : * * : :**:***
Mb0458c|M.bovis_AF2122/97 AAKNDDSFYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQSPEG
Rv0450c|M.tuberculosis_H37Rv AAKNDDSFYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQSPEG
MLBr_02378|M.leprae_Br4923 TAKNDDSFYLPPEVFKNTDFKRAMKSFLSSDGHAARFIILHRGDPASVAG
MMAR_1877|M.marinum_M TANNDDSFYLPPEVFTNANFKRIMKLFLSPDGHAARFIILHRGDPDRPEG
MAV_3249|M.avium_104 ASKNDDSFYLPPDIFDNADFKKAMSQFLSPDGKAARFIISHRGDPATSEA
MSMEG_0382|M.smegmatis_MC2_155 AAKNDDTFFLPPEVFDNPDFKRAMTSFLSPDGKAARFIISHNGDPATPEG
TH_3056|M.thermoresistible__bu ASHNDDSFYLPPEALENKDFQRVMEIFLSPDGKAARMLVTQRGDPATPEG
Mflv_4418|M.gilvum_PYR-GCK DSMNDDSFYLPPEAFDNDDFKRGMENFISPDGRSVRFIISHEGDPATVEG
Mvan_1936|M.vanbaalenii_PYR-1 DSMNDDSFYLPPEAFDNDDFKRGIENFISPDGKSVRFIIAHEGDPATVEG
MUL_0757|M.ulcerans_Agy99 SSRNDDSFYLPPEVFNNPDFKRGLEQFLSPDGHAVRFIISHEGDPMSQAG
MAB_2301|M.abscessus_ATCC_1997 AAKNDDSFYLPPEIFDNADFKRGMKSFLSPDGKAVRMIISHRGDPATPEG
: ***:*:***: : * :*:: : *:*.**::.*::: :.*** .
Mb0458c|M.bovis_AF2122/97 IKSIDAIRTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAI
Rv0450c|M.tuberculosis_H37Rv IKSIDAIRTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAI
MLBr_02378|M.leprae_Br4923 IASINAIRTAAEEALKGTPLEDTKIYLAGTAAVFKDIDEGANWDLVIAGI
MMAR_1877|M.marinum_M IARIDLIRTAAEESLKGSPLEDSRIYLTGTGAVSKDLSEGAKWDLLIAGI
MAV_3249|M.avium_104 LNRIDKIRSAAEEALKNTPLENAKIYLAGTASTFKDFRDGSTYDLFIAGV
MSMEG_0382|M.smegmatis_MC2_155 ISRVDQMQTAAVEALKGTPLTDAQVYLAGTAPTAKDWKDGSTYDLLIAGI
TH_3056|M.thermoresistible__bu MALVEPIYIAAEEALKGTPLESSRIYLAGSAAGVKDLVEGAKYDLMIAAI
Mflv_4418|M.gilvum_PYR-GCK ISEVVPIKTAAKEAIKGTPLEGSTVYLAGTAATYKDMSDGAFYDLLIAGI
Mvan_1936|M.vanbaalenii_PYR-1 ISRVLPIKTAAKEAIKGTPLEGSTVYLAGTAATYKDMRDGANYDLLIAGI
MUL_0757|M.ulcerans_Agy99 INHIDKIKTAAKEAIKGTPLEGSTIYLGGTVAMFKDLSDGNTFDLMIAGI
MAB_2301|M.abscessus_ATCC_1997 LSHVEPIKQAAIEAVKGTPLEDAKIELGGTAAVFKDMSDGAKYDLMIAGI
: : : ** *::*.:** .: : * *: . :* :* :**.**.:
Mb0458c|M.bovis_AF2122/97 SSLCLIFIIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHILAIHL
Rv0450c|M.tuberculosis_H37Rv SSLCLIFIIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHILAIHL
MLBr_02378|M.leprae_Br4923 SSLCLIFIIMLIITRAFVAAAVIVGTVALSLGASFGLSVLLWQHILGIEL
MMAR_1877|M.marinum_M ASLCLIFIIMLILTRALIAATVIVGTVALSLGASFGLSVLVWQHIFGIKL
MAV_3249|M.avium_104 GALCLIFIIMLILTRSFIAALVIVGTVTLSLGASFGLSVLIWQYIFGIQL
MSMEG_0382|M.smegmatis_MC2_155 AAMCLIFIIMLIVTRSFIAALVIVGTVVLSLGASFGLSVLLWQYILGIHL
TH_3056|M.thermoresistible__bu SAVCLIFMIMVFMTRSVIAALVIVGTVVLSLGASFGMSVLLWQHLLGIQL
Mflv_4418|M.gilvum_PYR-GCK AAVTLIFVIMLVITRSVVAAAVIVGTVLLSLGASFGLSVLLWQHIIGLAL
Mvan_1936|M.vanbaalenii_PYR-1 AAVTLIFVIMLIITRSVVAAAVIVGTVLLSLGASFGLSVLLWQHIIGLAL
MUL_0757|M.ulcerans_Agy99 SALCLIFIIMLIITRSVVAAAVIVGTVVLSLGASFGLSVLIWQHVLGIEL
MAB_2301|M.abscessus_ATCC_1997 SALCLIFLIMLLITRSFVASLVIVGTVALSLGASFGLSVIIWQYILGIEL
.:: ***:**:.:**:.:*: ****** ********:**::**:::.: *
Mb0458c|M.bovis_AF2122/97 HWLVLAMSVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVV
Rv0450c|M.tuberculosis_H37Rv HWLVLAMSVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVV
MLBr_02378|M.leprae_Br4923 HYLVLAMSVIVLLAVGSDYNLLLVSRFKQEIQAGLKTGIIRSMGGTGKVV
MMAR_1877|M.marinum_M HWLVLPMSVIVLLAVGSDYNLLLVSRFKQEIGAGLNTGIIRAIGGTGKVV
MAV_3249|M.avium_104 YWMVLPMSVIVLLAVGSDYNLLLVSRMKEEISAGINTGIIRAMGGTGKVV
MSMEG_0382|M.smegmatis_MC2_155 HWMVLAMSVIILLAVGSDYNLLLVSRIKEEVGAGINTGIVRAMGGTGKVV
TH_3056|M.thermoresistible__bu HWVVLAMSVIVLLAVGSDYNLMLVSRMKEEIGAGLNTGIIRAMGGTGRVV
Mflv_4418|M.gilvum_PYR-GCK HWMVLPMAVILLLAVGSDYNLLLVSRFKEELSGGLKTGIIRAMAGTGSVV
Mvan_1936|M.vanbaalenii_PYR-1 HWMVLPMAVILLLAVGSDYNLLLVSRFKEELAGGLKTGIIRSMAGTGSVV
MUL_0757|M.ulcerans_Agy99 HWLVLAMAVIILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGSGSVV
MAB_2301|M.abscessus_ATCC_1997 HWLVMQMAIIVLLAVGSDYNLLLVSRLKEELHGGLKTGIIRSMGGTGSVV
:::*: *::*:*****:****:**:*:*:*: .*::***:*::.*:* **
Mb0458c|M.bovis_AF2122/97 TNAGLVFAVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAA
Rv0450c|M.tuberculosis_H37Rv TNAGLVFAVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAA
MLBr_02378|M.leprae_Br4923 TNAGLVFAFTMASMVVSDLRVIGQVGTTIGLGLLFDTLIVRSFMMPSIAA
MMAR_1877|M.marinum_M TNAGLVFAITMASMIVSDLRIIGQVGTTISLGLLFDTLIVRAFMTPSIAA
MAV_3249|M.avium_104 TNAGLVFAFTMASMVVSDLRIIGQVGTTIGLGLMFDTLIVRSFMTPTIAA
MSMEG_0382|M.smegmatis_MC2_155 TSAGLVFAGTMAAMVVSDLRIIGQIGTTIGLGLLFDTMIVRSFMTPSIAA
TH_3056|M.thermoresistible__bu TMAGLVFAATMASMIVSDLLMIGQVGTTIALGLLFDTMVVRAFMTPSVAA
Mflv_4418|M.gilvum_PYR-GCK TSAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVRSFMTPAVAA
Mvan_1936|M.vanbaalenii_PYR-1 TSAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVRSFMTPAVAA
MUL_0757|M.ulcerans_Agy99 TAAGLVFAFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTPSIAA
MAB_2301|M.abscessus_ATCC_1997 TSAGLVFAFTMAVMVVSDLRIIGQVGTTIALGLLFDTLIVRSFMTPAVAT
* ****** ** : .*:* ::.*:****.:**:***::**:** *::*:
Mb0458c|M.bovis_AF2122/97 LLGRWFWWPLRVRSRPARTPTVP-------------SETQPAGRPLAMSS
Rv0450c|M.tuberculosis_H37Rv LLGRWFWWPLRVRSRPARTPTVP-------------SETQPAGRPLAMSS
MLBr_02378|M.leprae_Br4923 LLGRWFWWPQQGRTRPLLTVAAP-------------VGLPPD-RSLVYSD
MMAR_1877|M.marinum_M LLGRWFWWPLQVRTRPTRPTAVKPRRPDPPDHLPSVGERHQTRRLRALST
MAV_3249|M.avium_104 LLGRWFWWPQLVRRRPASQLLRS-------------EGTRRSVRVLLHQN
MSMEG_0382|M.smegmatis_MC2_155 LLGRWFWWPQKVRPRPASALLEP-------------YGPRPLVRALLEGP
TH_3056|M.thermoresistible__bu ILGRWFWWPQRVRTRPASAMLRP-------------VGPRPLVRSLLLRD
Mflv_4418|M.gilvum_PYR-GCK LLGRWFWWPQKFRSAASERRLAR-------------IGVQPATAGR----
Mvan_1936|M.vanbaalenii_PYR-1 LLGRWFWWPQKVRSHASQRRLAA-------------LNH-----------
MUL_0757|M.ulcerans_Agy99 LLGKWFWWPQVVRQRPAPQPWPT-------------PAPTPPPATTSV--
MAB_2301|M.abscessus_ATCC_1997 LLGRWFWWPLNVRTRPLPPPRTT-------------VAADPTPPPVPVGP
:**:***** * .
Mb0458c|M.bovis_AF2122/97 DRLG----------------------
Rv0450c|M.tuberculosis_H37Rv DRLG----------------------
MLBr_02378|M.leprae_Br4923 --------------------------
MMAR_1877|M.marinum_M ETLSPG--------------------
MAV_3249|M.avium_104 DDAD---------ADTAEIPVPRPTA
MSMEG_0382|M.smegmatis_MC2_155 SGAASPGGPGGRLSDDDTPTGPMRTR
TH_3056|M.thermoresistible__bu --------------------------
Mflv_4418|M.gilvum_PYR-GCK --------------------------
Mvan_1936|M.vanbaalenii_PYR-1 --------------------------
MUL_0757|M.ulcerans_Agy99 --------------------------
MAB_2301|M.abscessus_ATCC_1997 GHGDDPITTEFPRPSV----------