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M. smegmatis MC2 155 MSMEG_0381 (-)

annotation: Mmp14a protein
coordinates: 425760 - 428642
length: 960

MTEPATTQNREARPRIASFIRRFSVLIILAWIVVAALATFAIPPLEVVEREHSVSLSPPDAPSVQAMKRM
GEVFQESNSNSVAVLVLEGQEPLGDDAHRYYDEIIRKLKDDPEHVQHVQDFWGDPLTAGAAESGDRKAAY
VQINLHGSFGQAEANESVKAVQDAVESTPAPPGVQAFVTGPAAIVADMGESGNKTVLLITLVTVGVIFLM
LLLLYRRVLIVLILLATVAIELQVARGLVSFLALNGIVGLTTYVVNLLVSVGIAAGTDYGIFFAGRYQEA
RQAGEDREQAYYTSFAGVAKVVLASGATIAGAIACLSFTRLPYFQPLGIPGAVGIGVAVAVALTLVPACI
AATNRFGWFDPRRLVTTRRWRRIGTAVVRWPAPILIATIAVAVIGLLTLPGYNPSYSDQKYIPQDIPANQ
GFAAAARHFPESKMTTPDILLVEADHDMRNSADLLVLNKLAKAVFAVPGVSNVQAITRPEGTPIEHTSIP
FMLSMSNASQRLSLPFQQQRMEDLLKQADELTKNIALMKHMYALMQEMVATTHSTVETTHEVQQTTKDLR
DSIEDFQDFWRPIRNYLYWEPHCYDIPLCWSIRSLFDGLDGINEVTDKMGDLVEDLDHLDTLMPQMLLQF
PPMIAMLENSRSMILTMHSTMSGIFSQMDDSTDNATAMGKAFDAARNDDSFYLPPDILENEDFKRVMKIF
MSPDGKAARMLITQRGDPATPEGIALVEPIRVAAEEALKGTPLESAELHLAGTAAGVKDLVDGSKIDLLI
AGVAALCLIFIIMLIMTRSFIAALVIVGTVAMSLGASFGLSVLVWQHLLGIQINWVVLAMSVIVLLAVGS
DYNLLLVSRMKEEIGAGLNTGIIRAMGGTGKVVTAAGLVFAATMASMIVSDLLTIGQVGTTIGLGLLFDT
LVVRAFMTPSIAALLGRWFWWPQRVRQRPASAMLRSVGPRPLVRSLLLRD
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_0381--100% (960)Mmp14a protein
M. smegmatis MC2 155MSMEG_0382-0.061.97% (965) putative transport protein
M. smegmatis MC2 155MSMEG_3496-0.059.56% (947) MmpL4 protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0458cmmpL40.063.57% (936) transmembrane transport protein MmpL4
M. gilvum PYR-GCKMflv_2705-0.057.32% (949) transport protein
M. tuberculosis H37RvRv0450cmmpL40.063.68% (936) transmembrane transport protein MmpL4
M. leprae Br4923MLBr_02378-0.061.67% (947) hypothetical protein MLBr_02378
M. abscessus ATCC 19977MAB_4116c-0.078.29% (949) putative membrane protein, MmpL
M. marinum MMMAR_0771mmpL5_20.064.13% (934) transmembrane transport protein MmpL5_2
M. avium 104MAV_3248-0.067.47% (959) Mmp14A protein
M. thermoresistible (build 8)TH_3056-0.075.42% (948) PUTATIVE Mmp14a protein
M. ulcerans Agy99MUL_0757mmpL50.056.91% (940) transmembrane transport protein, MmpL5
M. vanbaalenii PYR-1Mvan_3833-0.057.36% (924) transport protein

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_0381|M.smegmatis_MC2_155      --------MTEPATTQNREARPRIASFIRRFSVLIILAWIVVAALATFAI
MAB_4116c|M.abscessus_ATCC_199      ---------MSADDGKVKSHRPIMATIIRRGAVFIILGWLAITVLLTVKV
TH_3056|M.thermoresistible__bu      --------MSVLDRVGVEPRRPRVASFIRRYSVLIILGWVALTVLATVAV
MAV_3248|M.avium_104                --------MSTQQLETQQAARPRVARIIHRLSVPIILGWLAVAVLITIGV
Mb0458c|M.bovis_AF2122/97           ----MSTKFANDSNTNARPEKPFIARMIHAFAVPIILGWLAVCVVVTVFV
Rv0450c|M.tuberculosis_H37Rv        ----MSTKFANDSNTNARPEKPFIARMIHAFAVPIILGWLAVCVVVTVFV
MMAR_0771|M.marinum_M               ----MTVKYANDPDTRTHTEKPFLARMIHAFAVPIILAWVAVCVALSVFI
MLBr_02378|M.leprae_Br4923          ----MTVKCANDLDTHTKP--PFVARMIHRFAVPIILVWLAIAVTVSVFI
MUL_0757|M.ulcerans_Agy99           MTATTTDTPTDVVPPAEHPPRPFIPRMIRTFAVPLILGWVLLIAVLNSVV
Mflv_2705|M.gilvum_PYR-GCK          --------MSSSRDRAALREPRSVARWIRRLAVPIILGWLLLAVALNALV
Mvan_3833|M.vanbaalenii_PYR-1       --------MRAHADR-DLRDPTPVARWIRRLAIPIILGWVLLVAALNLLV
                                                           :.  *:  :: :** *: : .  .  :

MSMEG_0381|M.smegmatis_MC2_155      PPLEVVEREHSVSLSPPDAPSVQAMKRMGEVFQESNSNSVAVLVLEGQ--
MAB_4116c|M.abscessus_ATCC_199      PPLEIVEREHSVSLSPPDAPSVKAMTQMGKVFQESNSESVAVIVLEGE--
TH_3056|M.thermoresistible__bu      PPLEAVEREKSLSLIPYDAPAFAAMHRMGELFDEPDSESIAIIVLEGQ--
MAV_3248|M.avium_104                PSLEQVEAEHAVSLSPIGAPSFKAMERLGEDFKETNTGALAMILLEGQ--
Mb0458c|M.bovis_AF2122/97           PSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKEGDSDSFAMVIIEGN--
Rv0450c|M.tuberculosis_H37Rv        PSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKEGDSDSFAMVIIEGN--
MMAR_0771|M.marinum_M               PSLEVVGQERSVSLSPKDAPSYEAMKRIGAAFNEGNSDSQAMIVLEGK--
MLBr_02378|M.leprae_Br4923          PSLEDVGQERSVSLSPKDAPSYIAMQKMGQVFNEGNSDSVIMIVLEGD--
MUL_0757|M.ulcerans_Agy99           PQLEVVGQMQAVSMSPDAAPSMISMKHIGKVFREGDSDSAAMIVLEGQ--
Mflv_2705|M.gilvum_PYR-GCK          PQLEVVAAKNAVSMSPSNAPSMQAMADMGRLFEESDSDSIALIVLESETD
Mvan_3833|M.vanbaalenii_PYR-1       PQLEVVAAQNAVSMSPSDAPAMQAMSDMGRLFGESDSDSIAMVVLEGE--
                                    * ** *   .::*: *  **:  :*  :*  * * :: :  ::::*..  

MSMEG_0381|M.smegmatis_MC2_155      EPLGDDAHRYYDEIIRKLKDDPEHVQHVQDFWGDPLTAGAAESGDRKAAY
MAB_4116c|M.abscessus_ATCC_199      GTLGDDAHKYYDAVIRQLKDDPKHVQHVQDFWGDPLTAGAAQSADGKAAY
TH_3056|M.thermoresistible__bu      EPLGLEAHEYYDQLISQLREHPQYVQHIRDFWGDPLTAGAAQSDDGKAAF
MAV_3248|M.avium_104                QQLGDDAHTYYDRLIRLLENDHKHVQHVQNFWGDPLTRGAAQSQDGKAAY
Mb0458c|M.bovis_AF2122/97           QPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDPLTAAGVQSNDGKAAY
Rv0450c|M.tuberculosis_H37Rv        QPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDPLTAAGVQSNDGKAAY
MMAR_0771|M.marinum_M               DALGDDAHKYYDVLIRKLRADPRHVQSVQDFWGDPLTAAGAQSNDGKAAY
MLBr_02378|M.leprae_Br4923          KPLGDDAHRFYDGLIRKLRAD-KHVQSVQDFWGDPLTAPGAQSNDGKAAY
MUL_0757|M.ulcerans_Agy99           EPLGAAAHKFYDKMITKLRADTKHVQSVQDFWGDPLTATGAQSGDGKAAY
Mflv_2705|M.gilvum_PYR-GCK          QPLGDDAHEYYDGLIAALLADTENVRNIQDTWGDPLTEAAAQSSDGRAAY
Mvan_3833|M.vanbaalenii_PYR-1       QPLGDDAHAYYDQLIEKLEAAPDHVRNIQDMWGDPLTEAAAQSTDGHAAY
                                      **  ** :** ::  *      *: ::: ******  ..:* * :**:

MSMEG_0381|M.smegmatis_MC2_155      VQINLHGSFGQAEANESVKAVQDAVESTP-APPGVQAFVTGPAAIVADMG
MAB_4116c|M.abscessus_ATCC_199      VQLNLTGRFGQADANESVEAVQKVVRETPGLPPGVKAYVTGPAAIVSDMA
TH_3056|M.thermoresistible__bu      VQVNLVGRFGQAKVNEAVRAVQEIVERTP-APEGVETFVTGPAALGADAG
MAV_3248|M.avium_104                VQVNLNGNAGAAAGDESVAAIRKLVQEAS-PPPGLKVYVTGPAPIVADMN
Mb0458c|M.bovis_AF2122/97           VQLSLAGNQGTPLANESVEAVRSIVESTP-APPGIKAYVTGPSALAADMH
Rv0450c|M.tuberculosis_H37Rv        VQLSLAGNQGTPLANESVEAVRSIVESTP-APPGIKAYVTGPSALAADMH
MMAR_0771|M.marinum_M               VQLNLAGNQGEPLANESVEAVRKIVKETP-APPGVTTYVTGAAALVSDMH
MLBr_02378|M.leprae_Br4923          VQLSLAGNQGELLAQESIDAVRKIVVQTP-APPGITAWVTGASALIADMH
MUL_0757|M.ulcerans_Agy99           VQVKLAGNQGESLANESVEAVKTIVDSLQ-APPGVKVYVTGSAALVADQQ
Mflv_2705|M.gilvum_PYR-GCK          ATLNLAGNMGETESNEAVAAVRDIVANSP-PPPGVTVHVTGPAALIADVN
Mvan_3833|M.vanbaalenii_PYR-1       VALNLAGNMGETKSNESVAAVRDIVADSP-PPPGVQVHVTGPAALTADVN
                                    . :.* *  *    :*:: *::  *      * *: . ***.:.: :*  

MSMEG_0381|M.smegmatis_MC2_155      ESGNKTVLLITLVTVGVIFLMLLLLYRRVLIVLILLATVAIELQVARGLV
MAB_4116c|M.abscessus_ATCC_199      ESGNRTVILITLVSVGVIFLMLLLLYRSIITVIILLFTVGIELQVARGLV
TH_3056|M.thermoresistible__bu      DSGTATVILITLVTVAVIFLMLLFFFRSFLTVIVLLLTVAVELQVARGLV
MAV_3248|M.avium_104                IAGQKTVMLVTLASLIVIFVTLLLVYRSVITVILLLLIVGLELQIARGMV
Mb0458c|M.bovis_AF2122/97           HSGDRSMARITMVTVAVIFIMLLLVYRSIITVVLLLITVGVELTAARGVV
Rv0450c|M.tuberculosis_H37Rv        HSGDRSMARITMVTVAVIFIMLLLVYRSIITVVLLLITVGVELTAARGVV
MMAR_0771|M.marinum_M               SSGDKSMIKITVTTVAVIFIMLLLVYRSVITVVVLLLTVGVELTAARGVV
MLBr_02378|M.leprae_Br4923          HSGDKSMIRITATSVIVILVTLLLVYRSFITVILLLFTVGIESAVARGVV
MUL_0757|M.ulcerans_Agy99           LAGDRSLQLIEMVTFTVIIVMLLLVYRSIITAAIMLTMVVLGLLATRGGV
Mflv_2705|M.gilvum_PYR-GCK          IAGERSMALVLLVTFVVIIVLLLFFYRSISTVLLLLVVVGIQLLVARGVV
Mvan_3833|M.vanbaalenii_PYR-1       IAGESSMALILLVTFVVIIVLLLFFYRSITTVVLLLIMVGVQMSVARGVV
                                     :*  ::  :  .:. **:: **:.:* .  . ::*  * :    :** *

MSMEG_0381|M.smegmatis_MC2_155      SFLALNGIVGLTTYVVNLLVSVGIAAGTDYGIFFAGRYQEARQAGEDREQ
MAB_4116c|M.abscessus_ATCC_199      AFLGMHGIVGLTTFVVNLLVSVGIAAGTDYGIFFAGRYQEARQSGEDRES
TH_3056|M.thermoresistible__bu      AYLGLQGWVGLTTYVVNLLVSVGIAAGTDYGIFFFGRYQEAREAGEDRDS
MAV_3248|M.avium_104                ALLGHLGVVGLTTFAVNLLVAAVIATGTDYGIFFVGRYQEARQAGESREE
Mb0458c|M.bovis_AF2122/97           AVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFIIGRYQEARQAGEDKEA
Rv0450c|M.tuberculosis_H37Rv        AVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFIIGRYQEARQAGEDKEA
MMAR_0771|M.marinum_M               ALLGHSGAIGLSTFAVSLLTSLAIAAGTDYGIFIFGRYQEARQAGEDKET
MLBr_02378|M.leprae_Br4923          ALLGHTGLIGLSTFAVNLLTSLAIAAGTDYGIFITGRYQEARQANENKEA
MUL_0757|M.ulcerans_Agy99           AFLGYHRIIGLSTFATNLLVVLAIAAATDYAIFLIGRYQEARGLGQDRES
Mflv_2705|M.gilvum_PYR-GCK          AALAHVGVIGLSTYATNLLISLAVAAGTDYAIFLVGRYQEARASGADHEE
Mvan_3833|M.vanbaalenii_PYR-1       AALGHFQVIGLSTFAVNLLISLAVAAGTDYAIFLVGRYQEARASGADPEA
                                    : *.    :**:*:...**    :*:.***.**: *******  . . : 

MSMEG_0381|M.smegmatis_MC2_155      AYYTSFAGVAKVVLASGATIAGAIACLSFTRLPYFQPLGIPGAVGIGVAV
MAB_4116c|M.abscessus_ATCC_199      AYYTAYKGVAKVVLASGLTIAGAIACLHFTRLPYFKPLGIPGAVGILVAV
TH_3056|M.thermoresistible__bu      AYFTTYRSVAKVVLASGLTIAGAIACLSFTRLPHFQPLGIPGAVGLLVAV
MAV_3248|M.avium_104                AFYTTFNGVAKVVLASGLTIAGAVLCLSFTRLPYFQPLGIPVAVGISIAV
Mb0458c|M.bovis_AF2122/97           AYYTMYRGTAHVILGSGLTITGATFCLSFARMPYFQTLGIPCAVGMLVAV
Rv0450c|M.tuberculosis_H37Rv        AYYTMYRGTAHVILGSGLTIAGATFCLSFARMPYFQTLGIPCAVGMLVAV
MMAR_0771|M.marinum_M               AFYTMYRGTAHVILGSGLTIAGATFCLKFARMPYFETLGIPCAVGMLVAV
MLBr_02378|M.leprae_Br4923          AFYTMYRGTFHVILGSGLTISGATFCLSFARMPYFQTLGVPCAVGMLIAV
MUL_0757|M.ulcerans_Agy99           AYYTMFGGTAHVVLGSGLTIAGATFCLSFTRLPYFQTLGVPLAIGMVIVV
Mflv_2705|M.gilvum_PYR-GCK          AYYEMFHGTAHVVLGSGLTIAGAMLCLSFTRMPYFQSMGIPCAVGIAAGV
Mvan_3833|M.vanbaalenii_PYR-1       AYYEMFGGTAHVVLGSGLTIAGAMYCLSFARMPYFQSMGVPCAVGILAGV
                                    *::  : .. :*:*.** **:**  ** *:*:*:*:.:*:* *:*:   *

MSMEG_0381|M.smegmatis_MC2_155      AVALTLVPACIAATNRFG-WFDPRRLVTTRRWRRIGTAVVRWPAPILIAT
MAB_4116c|M.abscessus_ATCC_199      AVALTLVPACIAAGSRFG-LFDPKRQVTTRRWRRVGTAIVRWPGPILAAT
TH_3056|M.thermoresistible__bu      AVALTLVPATIALGSRFG-LFEPKRRVMTHRWRRIGTAVVRWPVPILTAA
MAV_3248|M.avium_104                LVALTLGPALLAAGARFG-LFEPRRAVSARRWRRIGTAIVRWPAPILIAT
Mb0458c|M.bovis_AF2122/97           AVALTLGPAVLHVGSRFG-LFDPKRLLKVRGWRRVGTVVVRWPLPVLVAT
Rv0450c|M.tuberculosis_H37Rv        AVALTLGPAVLHVGSRFG-LFDPKRLLKVRGWRRVGTVVVRWPLPVLVAT
MMAR_0771|M.marinum_M               MVALTLGPAVLTVGSRFG-LFDPKRLIKVRGWRRVGTVVVRWPLPVLAAT
MLBr_02378|M.leprae_Br4923          AVALTLGPAVLTVGSRFG-LFEPKRLIKVRGWRRIGTVVVRWPLPILITT
MUL_0757|M.ulcerans_Agy99           ATALTLGPALIAVMSRFGKLLEPKRMARVRGWRKIGAAIVRWPGPILIGA
Mflv_2705|M.gilvum_PYR-GCK          AVALTLGPAIVTVGSRFN-LLEPKRAMRIRAWRRIGTMVVRWPGPILVAS
Mvan_3833|M.vanbaalenii_PYR-1       AVALTLGPAIVTVGSRFG-LLEPKRAMRIRAWRRVGATVVRWPGPILVAS
                                     .**** ** :    **.  ::*:*    : **::*: :**** *:*  :

MSMEG_0381|M.smegmatis_MC2_155      IAVAVIGLLTLPGYNPSYSDQKYIPQDIPANQGFAAAARHFPESKMTTPD
MAB_4116c|M.abscessus_ATCC_199      VAVALIGLLTLPGYNPSYTDAKFIPQDIPATQGLVAASRHFPESKMSTPD
TH_3056|M.thermoresistible__bu      VALSLVGLLTLPGYNPSYSDQEFIPDDIPASEGYKAAARHFPASAMSVPD
MAV_3248|M.avium_104                LAVSLVGLLALPNYRPSYDDQKFIPDSIPANVGYAAAARHFPGQRMQMPE
Mb0458c|M.bovis_AF2122/97           CAIALVGLLALPGYKTSYNDRDYLPDFIPANQGYAAADRHFSQARMK-PE
Rv0450c|M.tuberculosis_H37Rv        CAIALVGLLALPGYKTSYNDRDYLPDFIPANQGYAAADRHFSQARMK-PE
MMAR_0771|M.marinum_M               LAVALVGLLALPGYRTNYNDRDYLPNFIPANQGFTAAERHFSQARMK-PD
MLBr_02378|M.leprae_Br4923          CAIAMVGLLALPGYRTNYKDRAYLPASIPANQGFAAADRHFPQARMK-PE
MUL_0757|M.ulcerans_Agy99           VALALVGLLTLPGYKTNYNDRNYLPADLPANEGYSAAERHFSQARMN-PE
Mflv_2705|M.gilvum_PYR-GCK          LALALVGLAALPGYQTSYDDTRYVPESIPANAGLQAATQHFTLSRMS-PE
Mvan_3833|M.vanbaalenii_PYR-1       LALALIGLAALPGYKTSYDDTRYIPESIPANAGLQAATKYFSLSRMS-PE
                                     *::::** :**.*...* *  ::*  :**. *  ** ::*.   *  *:

MSMEG_0381|M.smegmatis_MC2_155      ILLVEADHDMRNSADLLVLNKLAKAVFAVPGVSNVQAITRPEGTPIEHTS
MAB_4116c|M.abscessus_ATCC_199      ILLIEANHDMRNSADLLVLNRLAKAVFAVPGIANVQSITRPEGTQIEHSS
TH_3056|M.thermoresistible__bu      VVLIEADRDMRNPADLLVLNKVAKKIFEVPGVANVQSVTRPEGRQIEHTT
MAV_3248|M.avium_104                ILLVETDHDLRNPTDMLVINKLAKGVLAVPGIATVQTVTRPEGVPLQHTT
Mb0458c|M.bovis_AF2122/97           ILMIESDHDMRNPADFLVLDKLAKGIFRVPGISRVQAITRPEGTTMDHTS
Rv0450c|M.tuberculosis_H37Rv        ILMIESDHDMRNPADFLVLDKLAKGIFRVPGISRVQAITRPEGTTMDHTS
MMAR_0771|M.marinum_M               ILMIQSDHDMRNPADFLVLDRLAKGIFHVPGISRVQAITRPDGTAMDHTS
MLBr_02378|M.leprae_Br4923          ILMIESDHDMRNPADFLILDKLARGIFRVPGISRVQAITRPDGTAMDHTS
MUL_0757|M.ulcerans_Agy99           VLMVESDHDMRNSSDFLVINKIAKAIFGVEGISRVQAITRPDGKPIEHTS
Mflv_2705|M.gilvum_PYR-GCK          ILIVEADRDLRNPADFLVLDRLAKRVFAVEGVARVQAPSRPDGSPIAKTS
Mvan_3833|M.vanbaalenii_PYR-1       VLIVEADRDLRNSSDFLILDRLAKRVFNVEGVARVQAPSRPDGAPIAHTS
                                    ::::::::*:**.:*:*:::::*: :: * *:: **: :**:*  : :::

MSMEG_0381|M.smegmatis_MC2_155      IPFMLSMSNASQRLSLPFQQQRMEDLLKQADELTKNIALMKHMYALMQEM
MAB_4116c|M.abscessus_ATCC_199      VPFMLSMSNASQRLSLPFQRARMDDMLKQADDMSKTIALMQRMSDLMNQM
TH_3056|M.thermoresistible__bu      IPFMLSMSQASQRLALPFQRARMDDMLKQADELTETIALMRRMQSLMEKM
MAV_3248|M.avium_104                IPWIISMGQASQLQNMAFQKDRMNDMLVQANELGKMIGIMQHMLDLMREL
Mb0458c|M.bovis_AF2122/97           IPFQISMQNAGQLQTIKYQRDRANDMLKQADEMATTIAVLTRMHSLMAEM
Rv0450c|M.tuberculosis_H37Rv        IPFQISMQNAGQLQTIKYQRDRANDMLKQADEMATTIAVLTRMHSLMAEM
MMAR_0771|M.marinum_M               IPFQISMQNAGQIQTLKYQRDRMNDMLTQAEEMAKTIALMRRMYGLMTQL
MLBr_02378|M.leprae_Br4923          IPFQISMQNAGQVQTMKYQKDRMNDLLRQAENMAETIASMRRMHQLMALL
MUL_0757|M.ulcerans_Agy99           IPFLISMQGTSQKLTEKYNQDLTTSMLQQVNDIQTNIDQMERMHDLTQQM
Mflv_2705|M.gilvum_PYR-GCK          IPFLISMQGVGQQQNMKLMQDRMDDMRTQADNLGKTLGTMRTMYGLMTRL
Mvan_3833|M.vanbaalenii_PYR-1       IPFLISMQGVGQQQNMKLMKDRIADMRVQADDIGETIATMKTMYGLMTKF
                                    :*: :**  ..*       :    .:  *.:::   :  :  *  *   :

MSMEG_0381|M.smegmatis_MC2_155      VATTHSTVETTHEVQQTTKDLRDSIEDFQDFWRPIRNYLYWEPHCYDIPL
MAB_4116c|M.abscessus_ATCC_199      VDTTHRMVSTTKDLQQDMRTLRDHIEDFEDFWRPIRNYFYWDKHCFDIPI
TH_3056|M.thermoresistible__bu      VATTHSMVGTTHELLDTTRDLRDHIADFDDFFRPIRNYFHWEPHCYNIPI
MAV_3248|M.avium_104                VATTHHMVQTTHEMQEITGELRDHISDFEDFWRPLRSYFYWEKHCYDIPI
Mb0458c|M.bovis_AF2122/97           ASTTHRMVGDTEEMKEITEELRDHVADFDDFWRPIRSYFYWEKHCYGIPI
Rv0450c|M.tuberculosis_H37Rv        ASTTHRMVGDTEEMKEITEELRDHVADFDDFWRPIRSYFYWEKHCYGIPI
MMAR_0771|M.marinum_M               ANNTHKMVGDTIEMQQITKELRDHIANFDDFFRPIRSYFYWEKHCYDIPI
MLBr_02378|M.leprae_Br4923          TENTHHILNDTVEMQKTTSKLRDEIANFDDFWRPIRSYFYWERHCFNIPI
MUL_0757|M.ulcerans_Agy99           ADVTHQMVIQMKGMVVDVEELRNHIADFDDFFRPIRSYFYWEKHCFDIPV
Mflv_2705|M.gilvum_PYR-GCK          SEVTTVMIDDFTEMQQTVHQIRDMVANFDDQFRPVRNYFYWEPHCYNIPL
Mvan_3833|M.vanbaalenii_PYR-1       SNITTVMIDDMTEMRDTVHQIRDMVATFDDQFRPIRNYFYWEPHCYNIPL
                                       *   :     :      :*: :  *:* :**:*.*::*: **:.**:

MSMEG_0381|M.smegmatis_MC2_155      CWSIRSLFDGLDGINEVTDKMGDLVEDLDHLDTLMPQMLLQFPPMIAMLE
MAB_4116c|M.abscessus_ATCC_199      CWSIRSIFDALDGVDQVTDKMQTLVGDLDELDKLMPQLLEQFPIMIETMK
TH_3056|M.thermoresistible__bu      CWSIRSIFDALDGINEMTEKMEELVEDMDRLDALMPQMLVQFPQMIETME
MAV_3248|M.avium_104                CFSLRSIFDALDGVDEINDKLGDLVKNLDQLDAILPQLVMQIPPMIETMS
Mb0458c|M.bovis_AF2122/97           CWSFRSIFDALDGIDKLSEQIGVLLGDLREMDRLMPQMVAQIPPQIEAME
Rv0450c|M.tuberculosis_H37Rv        CWSFRSIFDALDGIDKLSEQIGVLLGDLREMDRLMPQMVAQIPPQIEAME
MMAR_0771|M.marinum_M               CSSFRSIFDALDGIDQIDEKLDNLVVDIKELDRLMPQMIETFPPMIETME
MLBr_02378|M.leprae_Br4923          CWSFRSIFDALDGVDQIDERLNSIVGDIKNMDLLMPQMLEQFPPMIESME
MUL_0757|M.ulcerans_Agy99           CWSLRSVFDTLDGVDLMTEDINNLLPLMERLDTLMPQMTAMMPEMIQTMK
Mflv_2705|M.gilvum_PYR-GCK          CWSFRSLFDSMDGISTMTESFDKALVNMETMRSLLPQMLATFPPMIETME
Mvan_3833|M.vanbaalenii_PYR-1       CWSFRSLFDSMDGISVMTDTFDKAVANMDEMKALLPQMLATFPPMIETME
                                    * *:**:** :**:. : : :   :  :  :  ::**:   :*  *  :.

MSMEG_0381|M.smegmatis_MC2_155      NSRSMILTMHSTMSGIFSQMDDSTDNATAMGKAFDAARNDDSFYLPPDIL
MAB_4116c|M.abscessus_ATCC_199      STRESMLTMHSTMSGIFAQMDESTENSTAMGKAFDASKNDDSFYLPPDVL
TH_3056|M.thermoresistible__bu      SSRTMILTMHATMSGIFDQMESSSENATAMGKAFDASHNDDSFYLPPEAL
MAV_3248|M.avium_104                GMRTMMLTMHSTMSGVIGQMDSSAKDPSAMGQAFDASRNDDSFYLPPGII
Mb0458c|M.bovis_AF2122/97           NMRTMILTMHSTMTGIFDQMLEMSDNATAMGKAFDAAKNDDSFYLPPEVF
Rv0450c|M.tuberculosis_H37Rv        NMRTMILTMHSTMTGIFDQMLEMSDNATAMGKAFDAAKNDDSFYLPPEVF
MMAR_0771|M.marinum_M               SMRLMMLTMHSTMSGLYDQMSEMSENANAMGKAFDAAKNDDSFYLPPEVF
MLBr_02378|M.leprae_Br4923          SMRTIMLTMHSTMSGIFDQMNELSDNANTMGKAFDTAKNDDSFYLPPEVF
MUL_0757|M.ulcerans_Agy99           SMKAQMLSMHSTQQGLQDQMAAMQEDSSAMGEAFDSSRNDDSFYLPPEVF
Mflv_2705|M.gilvum_PYR-GCK          SMRQMMLTTYATMGGFYDQMDELTQDSTEMGKAFDEAKNDDSFYLPPEVF
Mvan_3833|M.vanbaalenii_PYR-1       SMRQMMLTTYATMGGFYDQMDELTRDSTEMGKAFDAAKNDDSFYLPPEVF
                                    . :  :*: ::*  *.  **     :.. **:*** ::*********  :

MSMEG_0381|M.smegmatis_MC2_155      ENED-FKRVMKIFMSPDGKAARMLITQRGDPATPEGIALVEPIRVAAEEA
MAB_4116c|M.abscessus_ATCC_199      KNKD-FQRVMKIFMSPDGKSSRMLISQRGDPATPEGISRVEPIKTAAEEA
TH_3056|M.thermoresistible__bu      ENKD-FQRVMEIFLSPDGKAARMLVTQRGDPATPEGMALVEPIYIAAEEA
MAV_3248|M.avium_104                NGSDSFKRVEKVFMSPDGKDVRLLITQRGDPATPEGLSRVEQIKTAAEES
Mb0458c|M.bovis_AF2122/97           KNKD-FQRAMKSFLSSDGHAARFIILHRGDPQSPEGIKSIDAIRTAAEES
Rv0450c|M.tuberculosis_H37Rv        KNKD-FQRAMKSFLSSDGHAARFIILHRGDPQSPEGIKSIDAIRTAAEES
MMAR_0771|M.marinum_M               KNED-FKRAMKSFLSPDGHAARFIILHRGDPQSAQGIASIDQIRTAAEES
MLBr_02378|M.leprae_Br4923          KNTD-FKRAMKSFLSSDGHAARFIILHRGDPASVAGIASINAIRTAAEEA
MUL_0757|M.ulcerans_Agy99           NNPD-FKRGLEQFLSPDGHAVRFIISHEGDPMSQAGINHIDKIKTAAKEA
Mflv_2705|M.gilvum_PYR-GCK          ENED-FKRAMESFFSPDGKTVRMLVSHRGDPTTPEALARVEPIKIAAIEA
Mvan_3833|M.vanbaalenii_PYR-1       ENED-FKRAMESFFSPDGKTVRMLIAHRGNPTTDEALQRVEPIKIAAIEA
                                    :. * *:*  : *:*.**:  *::: :.*:* :  .:  :: *  ** *:

MSMEG_0381|M.smegmatis_MC2_155      LKGTPLESAELHLAGTAAGVKDLVDGSKIDLLIAGVAALCLIFIIMLIMT
MAB_4116c|M.abscessus_ATCC_199      LKGTPLEHAKLSLAGTAAGVSELVEGSKYDLLIAGVAALCLIFIIMLLMT
TH_3056|M.thermoresistible__bu      LKGTPLESSRIYLAGSAAGVKDLVEGAKYDLMIAAISAVCLIFMIMVFMT
MAV_3248|M.avium_104                LKGTPLENSKIYLTGTAAITKDLVDGSKFDLLIAGVSALCLIFIIMLIMT
Mb0458c|M.bovis_AF2122/97           LKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAISSLCLIFIIMLIIT
Rv0450c|M.tuberculosis_H37Rv        LKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAISSLCLIFIIMLIIT
MMAR_0771|M.marinum_M               LKGTPLEDAKIYVAGTASVFKDISEGADWDLLIAGISSLCLIFIIMLILT
MLBr_02378|M.leprae_Br4923          LKGTPLEDTKIYLAGTAAVFKDIDEGANWDLVIAGISSLCLIFIIMLIIT
MUL_0757|M.ulcerans_Agy99           IKGTPLEGSTIYLGGTVAMFKDLSDGNTFDLMIAGISALCLIFIIMLIIT
Mflv_2705|M.gilvum_PYR-GCK          LKGTPLENAQIQLGGTAATFKDMSDGSRYDMMIAILSALCLVLVIMLVLT
Mvan_3833|M.vanbaalenii_PYR-1       LKGTPLENAQIQLGGTAATFKDMSDGSRYDLLIAVISALCLVLMIMLVLT
                                    :****** : : : *:.:   :: :*   *::** ::::**:::**:.:*

MSMEG_0381|M.smegmatis_MC2_155      RSFIAALVIVGTVAMSLGASFGLSVLVWQHLLGIQINWVVLAMSVIVLLA
MAB_4116c|M.abscessus_ATCC_199      RSLVAALVIVGTVALSLGASFGLSVLVWQHICGIQINWVVLAMSVIVLLA
TH_3056|M.thermoresistible__bu      RSVIAALVIVGTVVLSLGASFGMSVLLWQHLLGIQLHWVVLAMSVIVLLA
MAV_3248|M.avium_104                RSFIAAMVIVGTVLLSLGASFGLSVLVWQYLLHMQLHWTVLSTSVIVLLA
Mb0458c|M.bovis_AF2122/97           RAFIAAAVIVGTVALSLGASFGLSVLLWQHILAIHLHWLVLAMSVIVLLA
Rv0450c|M.tuberculosis_H37Rv        RAFIAAAVIVGTVALSLGASFGLSVLLWQHILAIHLHWLVLAMSVIVLLA
MMAR_0771|M.marinum_M               RAFVAAAVIVGTVALSLGASFGMSVLLWQHILNIDLHYMVLAMSVIVLLA
MLBr_02378|M.leprae_Br4923          RAFVAAAVIVGTVALSLGASFGLSVLLWQHILGIELHYLVLAMSVIVLLA
MUL_0757|M.ulcerans_Agy99           RSVVAAAVIVGTVVLSLGASFGLSVLIWQHVLGIELHWLVLAMAVIILLA
Mflv_2705|M.gilvum_PYR-GCK          RSLVAAVVIVGTVALSLGASFGVSVLIWQHLLGVELHWMVLVMSIIALIA
Mvan_3833|M.vanbaalenii_PYR-1       RSLVAALVIVGTVTLSLGASFGISILIWQHIVGIELHWMVLALSIIALIA
                                    *:.:** ****** :*******:*:*:**::  :.::: **  ::* *:*

MSMEG_0381|M.smegmatis_MC2_155      VGSDYNLLLVSRMKEEIGAGLNTGIIRAMGGTGKVVTAAGLVFAATMASM
MAB_4116c|M.abscessus_ATCC_199      VGSDYNLLLVSRMKEELGAGLKTGIIRAMGGTGKVVTAAGLVFAATMGSM
TH_3056|M.thermoresistible__bu      VGSDYNLMLVSRMKEEIGAGLNTGIIRAMGGTGRVVTMAGLVFAATMASM
MAV_3248|M.avium_104                VGSDYNLLLVSRMKEELAAGIHTGIIRAMGGTGKVVTNAGLVFAFTMGAM
Mb0458c|M.bovis_AF2122/97           VGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVVTNAGLVFAVTMASM
Rv0450c|M.tuberculosis_H37Rv        VGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVVTNAGLVFAVTMASM
MMAR_0771|M.marinum_M               VGSDYNLLLVSRFKEEIPAGLKTGIIRAMGGTGKVVTNAGLVFAFTMASM
MLBr_02378|M.leprae_Br4923          VGSDYNLLLVSRFKQEIQAGLKTGIIRSMGGTGKVVTNAGLVFAFTMASM
MUL_0757|M.ulcerans_Agy99           VGADYNLLLVARLKEEIHAGINTGIIRAMGGSGSVVTAAGLVFAFTMMSF
Mflv_2705|M.gilvum_PYR-GCK          VGSDYNLLLVSRFKEEIGAGIKTGIIRAIGGTGSVVSVAGVVFALTMASM
Mvan_3833|M.vanbaalenii_PYR-1       VGSDYNLLLVSRFKEEIPAGIKTGIIRAIGGTGSVVTVAGVVFALTMASM
                                    **:****:**:*:*:*: **::*****::**:* **: **:*** ** ::

MSMEG_0381|M.smegmatis_MC2_155      IVSDLLTIGQVGTTIGLGLLFDTLVVRAFMTPSIAALLGRWFWWPQRVRQ
MAB_4116c|M.abscessus_ATCC_199      IVSDLLTIGQVGTTIGLGLLFDTLIVRAFMTPAIAALLGRWFWWPLQVSP
TH_3056|M.thermoresistible__bu      IVSDLLMIGQVGTTIALGLLFDTMVVRAFMTPSVAAILGRWFWWPQRVRT
MAV_3248|M.avium_104                VVSDLRSIGQVGTTIGLGLLFDTLIVRAFMTPSVAALLGRWFWWPQLVRP
Mb0458c|M.bovis_AF2122/97           AVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAALLGRWFWWPLRVRS
Rv0450c|M.tuberculosis_H37Rv        AVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAALLGRWFWWPLRVRS
MMAR_0771|M.marinum_M               AVSDLRVIGQVGTTIGLGLLFDTLIVRAFMTPSIAALLGRWFWWPMRVRT
MLBr_02378|M.leprae_Br4923          VVSDLRVIGQVGTTIGLGLLFDTLIVRSFMMPSIAALLGRWFWWPQQGRT
MUL_0757|M.ulcerans_Agy99           AVSELTVMAQVGTTIGMGLLFDTLIVRSFMTPSIAALLGKWFWWPQVVRQ
Mflv_2705|M.gilvum_PYR-GCK          VVSDLKVIAQVGTTIGLGLLFDTFIVRAFMMPSIATLLGRWFWWPLVVRS
Mvan_3833|M.vanbaalenii_PYR-1       VVSDLRVMAQVGTTIGLGLLFDTFIVRAFMMPAIATLLGRWFWWPLVVRS
                                     **:*  :.******.:******::**:** *::*::**:*****     

MSMEG_0381|M.smegmatis_MC2_155      RPASAMLRSVGPRPLVRSLLLRD----
MAB_4116c|M.abscessus_ATCC_199      RPVGAVRGWRGPR-LVRSVLQRN----
TH_3056|M.thermoresistible__bu      RPASAMLRPVGPRPLVRSLLLRD----
MAV_3248|M.avium_104                RPASTMLRPTGPRPLVRSLLLKQPQ--
Mb0458c|M.bovis_AF2122/97           RPARTPTVPSETQPAGRPLAMSSDRLG
Rv0450c|M.tuberculosis_H37Rv        RPARTPTVPSETQPAGRPLAMSSDRLG
MMAR_0771|M.marinum_M               RPARTPSSPTADPEPDRALAMSGER--
MLBr_02378|M.leprae_Br4923          RPLLTVAAPVG-LPPDRSLVYSD----
MUL_0757|M.ulcerans_Agy99           RPAPQPWPTPAPTPPPATTSV------
Mflv_2705|M.gilvum_PYR-GCK          RPLRPRPQQQALGVGGQQG--------
Mvan_3833|M.vanbaalenii_PYR-1       RPLRLPPRT------------------
                                    **