For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MTEPATTQNREARPRIASFIRRFSVLIILAWIVVAALATFAIPPLEVVEREHSVSLSPPDAPSVQAMKRM GEVFQESNSNSVAVLVLEGQEPLGDDAHRYYDEIIRKLKDDPEHVQHVQDFWGDPLTAGAAESGDRKAAY VQINLHGSFGQAEANESVKAVQDAVESTPAPPGVQAFVTGPAAIVADMGESGNKTVLLITLVTVGVIFLM LLLLYRRVLIVLILLATVAIELQVARGLVSFLALNGIVGLTTYVVNLLVSVGIAAGTDYGIFFAGRYQEA RQAGEDREQAYYTSFAGVAKVVLASGATIAGAIACLSFTRLPYFQPLGIPGAVGIGVAVAVALTLVPACI AATNRFGWFDPRRLVTTRRWRRIGTAVVRWPAPILIATIAVAVIGLLTLPGYNPSYSDQKYIPQDIPANQ GFAAAARHFPESKMTTPDILLVEADHDMRNSADLLVLNKLAKAVFAVPGVSNVQAITRPEGTPIEHTSIP FMLSMSNASQRLSLPFQQQRMEDLLKQADELTKNIALMKHMYALMQEMVATTHSTVETTHEVQQTTKDLR DSIEDFQDFWRPIRNYLYWEPHCYDIPLCWSIRSLFDGLDGINEVTDKMGDLVEDLDHLDTLMPQMLLQF PPMIAMLENSRSMILTMHSTMSGIFSQMDDSTDNATAMGKAFDAARNDDSFYLPPDILENEDFKRVMKIF MSPDGKAARMLITQRGDPATPEGIALVEPIRVAAEEALKGTPLESAELHLAGTAAGVKDLVDGSKIDLLI AGVAALCLIFIIMLIMTRSFIAALVIVGTVAMSLGASFGLSVLVWQHLLGIQINWVVLAMSVIVLLAVGS DYNLLLVSRMKEEIGAGLNTGIIRAMGGTGKVVTAAGLVFAATMASMIVSDLLTIGQVGTTIGLGLLFDT LVVRAFMTPSIAALLGRWFWWPQRVRQRPASAMLRSVGPRPLVRSLLLRD
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_0381 | - | - | 100% (960) | Mmp14a protein |
M. smegmatis MC2 155 | MSMEG_0382 | - | 0.0 | 61.97% (965) | putative transport protein |
M. smegmatis MC2 155 | MSMEG_3496 | - | 0.0 | 59.56% (947) | MmpL4 protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0458c | mmpL4 | 0.0 | 63.57% (936) | transmembrane transport protein MmpL4 |
M. gilvum PYR-GCK | Mflv_2705 | - | 0.0 | 57.32% (949) | transport protein |
M. tuberculosis H37Rv | Rv0450c | mmpL4 | 0.0 | 63.68% (936) | transmembrane transport protein MmpL4 |
M. leprae Br4923 | MLBr_02378 | - | 0.0 | 61.67% (947) | hypothetical protein MLBr_02378 |
M. abscessus ATCC 19977 | MAB_4116c | - | 0.0 | 78.29% (949) | putative membrane protein, MmpL |
M. marinum M | MMAR_0771 | mmpL5_2 | 0.0 | 64.13% (934) | transmembrane transport protein MmpL5_2 |
M. avium 104 | MAV_3248 | - | 0.0 | 67.47% (959) | Mmp14A protein |
M. thermoresistible (build 8) | TH_3056 | - | 0.0 | 75.42% (948) | PUTATIVE Mmp14a protein |
M. ulcerans Agy99 | MUL_0757 | mmpL5 | 0.0 | 56.91% (940) | transmembrane transport protein, MmpL5 |
M. vanbaalenii PYR-1 | Mvan_3833 | - | 0.0 | 57.36% (924) | transport protein |
CLUSTAL 2.0.9 multiple sequence alignment MSMEG_0381|M.smegmatis_MC2_155 --------MTEPATTQNREARPRIASFIRRFSVLIILAWIVVAALATFAI MAB_4116c|M.abscessus_ATCC_199 ---------MSADDGKVKSHRPIMATIIRRGAVFIILGWLAITVLLTVKV TH_3056|M.thermoresistible__bu --------MSVLDRVGVEPRRPRVASFIRRYSVLIILGWVALTVLATVAV MAV_3248|M.avium_104 --------MSTQQLETQQAARPRVARIIHRLSVPIILGWLAVAVLITIGV Mb0458c|M.bovis_AF2122/97 ----MSTKFANDSNTNARPEKPFIARMIHAFAVPIILGWLAVCVVVTVFV Rv0450c|M.tuberculosis_H37Rv ----MSTKFANDSNTNARPEKPFIARMIHAFAVPIILGWLAVCVVVTVFV MMAR_0771|M.marinum_M ----MTVKYANDPDTRTHTEKPFLARMIHAFAVPIILAWVAVCVALSVFI MLBr_02378|M.leprae_Br4923 ----MTVKCANDLDTHTKP--PFVARMIHRFAVPIILVWLAIAVTVSVFI MUL_0757|M.ulcerans_Agy99 MTATTTDTPTDVVPPAEHPPRPFIPRMIRTFAVPLILGWVLLIAVLNSVV Mflv_2705|M.gilvum_PYR-GCK --------MSSSRDRAALREPRSVARWIRRLAVPIILGWLLLAVALNALV Mvan_3833|M.vanbaalenii_PYR-1 --------MRAHADR-DLRDPTPVARWIRRLAIPIILGWVLLVAALNLLV :. *: :: :** *: : . . : MSMEG_0381|M.smegmatis_MC2_155 PPLEVVEREHSVSLSPPDAPSVQAMKRMGEVFQESNSNSVAVLVLEGQ-- MAB_4116c|M.abscessus_ATCC_199 PPLEIVEREHSVSLSPPDAPSVKAMTQMGKVFQESNSESVAVIVLEGE-- TH_3056|M.thermoresistible__bu PPLEAVEREKSLSLIPYDAPAFAAMHRMGELFDEPDSESIAIIVLEGQ-- MAV_3248|M.avium_104 PSLEQVEAEHAVSLSPIGAPSFKAMERLGEDFKETNTGALAMILLEGQ-- Mb0458c|M.bovis_AF2122/97 PSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKEGDSDSFAMVIIEGN-- Rv0450c|M.tuberculosis_H37Rv PSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKEGDSDSFAMVIIEGN-- MMAR_0771|M.marinum_M PSLEVVGQERSVSLSPKDAPSYEAMKRIGAAFNEGNSDSQAMIVLEGK-- MLBr_02378|M.leprae_Br4923 PSLEDVGQERSVSLSPKDAPSYIAMQKMGQVFNEGNSDSVIMIVLEGD-- MUL_0757|M.ulcerans_Agy99 PQLEVVGQMQAVSMSPDAAPSMISMKHIGKVFREGDSDSAAMIVLEGQ-- Mflv_2705|M.gilvum_PYR-GCK PQLEVVAAKNAVSMSPSNAPSMQAMADMGRLFEESDSDSIALIVLESETD Mvan_3833|M.vanbaalenii_PYR-1 PQLEVVAAQNAVSMSPSDAPAMQAMSDMGRLFGESDSDSIAMVVLEGE-- * ** * .::*: * **: :* :* * * :: : ::::*.. MSMEG_0381|M.smegmatis_MC2_155 EPLGDDAHRYYDEIIRKLKDDPEHVQHVQDFWGDPLTAGAAESGDRKAAY MAB_4116c|M.abscessus_ATCC_199 GTLGDDAHKYYDAVIRQLKDDPKHVQHVQDFWGDPLTAGAAQSADGKAAY TH_3056|M.thermoresistible__bu EPLGLEAHEYYDQLISQLREHPQYVQHIRDFWGDPLTAGAAQSDDGKAAF MAV_3248|M.avium_104 QQLGDDAHTYYDRLIRLLENDHKHVQHVQNFWGDPLTRGAAQSQDGKAAY Mb0458c|M.bovis_AF2122/97 QPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDPLTAAGVQSNDGKAAY Rv0450c|M.tuberculosis_H37Rv QPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDPLTAAGVQSNDGKAAY MMAR_0771|M.marinum_M DALGDDAHKYYDVLIRKLRADPRHVQSVQDFWGDPLTAAGAQSNDGKAAY MLBr_02378|M.leprae_Br4923 KPLGDDAHRFYDGLIRKLRAD-KHVQSVQDFWGDPLTAPGAQSNDGKAAY MUL_0757|M.ulcerans_Agy99 EPLGAAAHKFYDKMITKLRADTKHVQSVQDFWGDPLTATGAQSGDGKAAY Mflv_2705|M.gilvum_PYR-GCK QPLGDDAHEYYDGLIAALLADTENVRNIQDTWGDPLTEAAAQSSDGRAAY Mvan_3833|M.vanbaalenii_PYR-1 QPLGDDAHAYYDQLIEKLEAAPDHVRNIQDMWGDPLTEAAAQSTDGHAAY ** ** :** :: * *: ::: ****** ..:* * :**: MSMEG_0381|M.smegmatis_MC2_155 VQINLHGSFGQAEANESVKAVQDAVESTP-APPGVQAFVTGPAAIVADMG MAB_4116c|M.abscessus_ATCC_199 VQLNLTGRFGQADANESVEAVQKVVRETPGLPPGVKAYVTGPAAIVSDMA TH_3056|M.thermoresistible__bu VQVNLVGRFGQAKVNEAVRAVQEIVERTP-APEGVETFVTGPAALGADAG MAV_3248|M.avium_104 VQVNLNGNAGAAAGDESVAAIRKLVQEAS-PPPGLKVYVTGPAPIVADMN Mb0458c|M.bovis_AF2122/97 VQLSLAGNQGTPLANESVEAVRSIVESTP-APPGIKAYVTGPSALAADMH Rv0450c|M.tuberculosis_H37Rv VQLSLAGNQGTPLANESVEAVRSIVESTP-APPGIKAYVTGPSALAADMH MMAR_0771|M.marinum_M VQLNLAGNQGEPLANESVEAVRKIVKETP-APPGVTTYVTGAAALVSDMH MLBr_02378|M.leprae_Br4923 VQLSLAGNQGELLAQESIDAVRKIVVQTP-APPGITAWVTGASALIADMH MUL_0757|M.ulcerans_Agy99 VQVKLAGNQGESLANESVEAVKTIVDSLQ-APPGVKVYVTGSAALVADQQ Mflv_2705|M.gilvum_PYR-GCK ATLNLAGNMGETESNEAVAAVRDIVANSP-PPPGVTVHVTGPAALIADVN Mvan_3833|M.vanbaalenii_PYR-1 VALNLAGNMGETKSNESVAAVRDIVADSP-PPPGVQVHVTGPAALTADVN . :.* * * :*:: *:: * * *: . ***.:.: :* MSMEG_0381|M.smegmatis_MC2_155 ESGNKTVLLITLVTVGVIFLMLLLLYRRVLIVLILLATVAIELQVARGLV MAB_4116c|M.abscessus_ATCC_199 ESGNRTVILITLVSVGVIFLMLLLLYRSIITVIILLFTVGIELQVARGLV TH_3056|M.thermoresistible__bu DSGTATVILITLVTVAVIFLMLLFFFRSFLTVIVLLLTVAVELQVARGLV MAV_3248|M.avium_104 IAGQKTVMLVTLASLIVIFVTLLLVYRSVITVILLLLIVGLELQIARGMV Mb0458c|M.bovis_AF2122/97 HSGDRSMARITMVTVAVIFIMLLLVYRSIITVVLLLITVGVELTAARGVV Rv0450c|M.tuberculosis_H37Rv HSGDRSMARITMVTVAVIFIMLLLVYRSIITVVLLLITVGVELTAARGVV MMAR_0771|M.marinum_M SSGDKSMIKITVTTVAVIFIMLLLVYRSVITVVVLLLTVGVELTAARGVV MLBr_02378|M.leprae_Br4923 HSGDKSMIRITATSVIVILVTLLLVYRSFITVILLLFTVGIESAVARGVV MUL_0757|M.ulcerans_Agy99 LAGDRSLQLIEMVTFTVIIVMLLLVYRSIITAAIMLTMVVLGLLATRGGV Mflv_2705|M.gilvum_PYR-GCK IAGERSMALVLLVTFVVIIVLLLFFYRSISTVLLLLVVVGIQLLVARGVV Mvan_3833|M.vanbaalenii_PYR-1 IAGESSMALILLVTFVVIIVLLLFFYRSITTVVLLLIMVGVQMSVARGVV :* :: : .:. **:: **:.:* . . ::* * : :** * MSMEG_0381|M.smegmatis_MC2_155 SFLALNGIVGLTTYVVNLLVSVGIAAGTDYGIFFAGRYQEARQAGEDREQ MAB_4116c|M.abscessus_ATCC_199 AFLGMHGIVGLTTFVVNLLVSVGIAAGTDYGIFFAGRYQEARQSGEDRES TH_3056|M.thermoresistible__bu AYLGLQGWVGLTTYVVNLLVSVGIAAGTDYGIFFFGRYQEAREAGEDRDS MAV_3248|M.avium_104 ALLGHLGVVGLTTFAVNLLVAAVIATGTDYGIFFVGRYQEARQAGESREE Mb0458c|M.bovis_AF2122/97 AVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFIIGRYQEARQAGEDKEA Rv0450c|M.tuberculosis_H37Rv AVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFIIGRYQEARQAGEDKEA MMAR_0771|M.marinum_M ALLGHSGAIGLSTFAVSLLTSLAIAAGTDYGIFIFGRYQEARQAGEDKET MLBr_02378|M.leprae_Br4923 ALLGHTGLIGLSTFAVNLLTSLAIAAGTDYGIFITGRYQEARQANENKEA MUL_0757|M.ulcerans_Agy99 AFLGYHRIIGLSTFATNLLVVLAIAAATDYAIFLIGRYQEARGLGQDRES Mflv_2705|M.gilvum_PYR-GCK AALAHVGVIGLSTYATNLLISLAVAAGTDYAIFLVGRYQEARASGADHEE Mvan_3833|M.vanbaalenii_PYR-1 AALGHFQVIGLSTFAVNLLISLAVAAGTDYAIFLVGRYQEARASGADPEA : *. :**:*:...** :*:.***.**: ******* . . : MSMEG_0381|M.smegmatis_MC2_155 AYYTSFAGVAKVVLASGATIAGAIACLSFTRLPYFQPLGIPGAVGIGVAV MAB_4116c|M.abscessus_ATCC_199 AYYTAYKGVAKVVLASGLTIAGAIACLHFTRLPYFKPLGIPGAVGILVAV TH_3056|M.thermoresistible__bu AYFTTYRSVAKVVLASGLTIAGAIACLSFTRLPHFQPLGIPGAVGLLVAV MAV_3248|M.avium_104 AFYTTFNGVAKVVLASGLTIAGAVLCLSFTRLPYFQPLGIPVAVGISIAV Mb0458c|M.bovis_AF2122/97 AYYTMYRGTAHVILGSGLTITGATFCLSFARMPYFQTLGIPCAVGMLVAV Rv0450c|M.tuberculosis_H37Rv AYYTMYRGTAHVILGSGLTIAGATFCLSFARMPYFQTLGIPCAVGMLVAV MMAR_0771|M.marinum_M AFYTMYRGTAHVILGSGLTIAGATFCLKFARMPYFETLGIPCAVGMLVAV MLBr_02378|M.leprae_Br4923 AFYTMYRGTFHVILGSGLTISGATFCLSFARMPYFQTLGVPCAVGMLIAV MUL_0757|M.ulcerans_Agy99 AYYTMFGGTAHVVLGSGLTIAGATFCLSFTRLPYFQTLGVPLAIGMVIVV Mflv_2705|M.gilvum_PYR-GCK AYYEMFHGTAHVVLGSGLTIAGAMLCLSFTRMPYFQSMGIPCAVGIAAGV Mvan_3833|M.vanbaalenii_PYR-1 AYYEMFGGTAHVVLGSGLTIAGAMYCLSFARMPYFQSMGVPCAVGILAGV *:: : .. :*:*.** **:** ** *:*:*:*:.:*:* *:*: * MSMEG_0381|M.smegmatis_MC2_155 AVALTLVPACIAATNRFG-WFDPRRLVTTRRWRRIGTAVVRWPAPILIAT MAB_4116c|M.abscessus_ATCC_199 AVALTLVPACIAAGSRFG-LFDPKRQVTTRRWRRVGTAIVRWPGPILAAT TH_3056|M.thermoresistible__bu AVALTLVPATIALGSRFG-LFEPKRRVMTHRWRRIGTAVVRWPVPILTAA MAV_3248|M.avium_104 LVALTLGPALLAAGARFG-LFEPRRAVSARRWRRIGTAIVRWPAPILIAT Mb0458c|M.bovis_AF2122/97 AVALTLGPAVLHVGSRFG-LFDPKRLLKVRGWRRVGTVVVRWPLPVLVAT Rv0450c|M.tuberculosis_H37Rv AVALTLGPAVLHVGSRFG-LFDPKRLLKVRGWRRVGTVVVRWPLPVLVAT MMAR_0771|M.marinum_M MVALTLGPAVLTVGSRFG-LFDPKRLIKVRGWRRVGTVVVRWPLPVLAAT MLBr_02378|M.leprae_Br4923 AVALTLGPAVLTVGSRFG-LFEPKRLIKVRGWRRIGTVVVRWPLPILITT MUL_0757|M.ulcerans_Agy99 ATALTLGPALIAVMSRFGKLLEPKRMARVRGWRKIGAAIVRWPGPILIGA Mflv_2705|M.gilvum_PYR-GCK AVALTLGPAIVTVGSRFN-LLEPKRAMRIRAWRRIGTMVVRWPGPILVAS Mvan_3833|M.vanbaalenii_PYR-1 AVALTLGPAIVTVGSRFG-LLEPKRAMRIRAWRRVGATVVRWPGPILVAS .**** ** : **. ::*:* : **::*: :**** *:* : MSMEG_0381|M.smegmatis_MC2_155 IAVAVIGLLTLPGYNPSYSDQKYIPQDIPANQGFAAAARHFPESKMTTPD MAB_4116c|M.abscessus_ATCC_199 VAVALIGLLTLPGYNPSYTDAKFIPQDIPATQGLVAASRHFPESKMSTPD TH_3056|M.thermoresistible__bu VALSLVGLLTLPGYNPSYSDQEFIPDDIPASEGYKAAARHFPASAMSVPD MAV_3248|M.avium_104 LAVSLVGLLALPNYRPSYDDQKFIPDSIPANVGYAAAARHFPGQRMQMPE Mb0458c|M.bovis_AF2122/97 CAIALVGLLALPGYKTSYNDRDYLPDFIPANQGYAAADRHFSQARMK-PE Rv0450c|M.tuberculosis_H37Rv CAIALVGLLALPGYKTSYNDRDYLPDFIPANQGYAAADRHFSQARMK-PE MMAR_0771|M.marinum_M LAVALVGLLALPGYRTNYNDRDYLPNFIPANQGFTAAERHFSQARMK-PD MLBr_02378|M.leprae_Br4923 CAIAMVGLLALPGYRTNYKDRAYLPASIPANQGFAAADRHFPQARMK-PE MUL_0757|M.ulcerans_Agy99 VALALVGLLTLPGYKTNYNDRNYLPADLPANEGYSAAERHFSQARMN-PE Mflv_2705|M.gilvum_PYR-GCK LALALVGLAALPGYQTSYDDTRYVPESIPANAGLQAATQHFTLSRMS-PE Mvan_3833|M.vanbaalenii_PYR-1 LALALIGLAALPGYKTSYDDTRYIPESIPANAGLQAATKYFSLSRMS-PE *::::** :**.*...* * ::* :**. * ** ::*. * *: MSMEG_0381|M.smegmatis_MC2_155 ILLVEADHDMRNSADLLVLNKLAKAVFAVPGVSNVQAITRPEGTPIEHTS MAB_4116c|M.abscessus_ATCC_199 ILLIEANHDMRNSADLLVLNRLAKAVFAVPGIANVQSITRPEGTQIEHSS TH_3056|M.thermoresistible__bu VVLIEADRDMRNPADLLVLNKVAKKIFEVPGVANVQSVTRPEGRQIEHTT MAV_3248|M.avium_104 ILLVETDHDLRNPTDMLVINKLAKGVLAVPGIATVQTVTRPEGVPLQHTT Mb0458c|M.bovis_AF2122/97 ILMIESDHDMRNPADFLVLDKLAKGIFRVPGISRVQAITRPEGTTMDHTS Rv0450c|M.tuberculosis_H37Rv ILMIESDHDMRNPADFLVLDKLAKGIFRVPGISRVQAITRPEGTTMDHTS MMAR_0771|M.marinum_M ILMIQSDHDMRNPADFLVLDRLAKGIFHVPGISRVQAITRPDGTAMDHTS MLBr_02378|M.leprae_Br4923 ILMIESDHDMRNPADFLILDKLARGIFRVPGISRVQAITRPDGTAMDHTS MUL_0757|M.ulcerans_Agy99 VLMVESDHDMRNSSDFLVINKIAKAIFGVEGISRVQAITRPDGKPIEHTS Mflv_2705|M.gilvum_PYR-GCK ILIVEADRDLRNPADFLVLDRLAKRVFAVEGVARVQAPSRPDGSPIAKTS Mvan_3833|M.vanbaalenii_PYR-1 VLIVEADRDLRNSSDFLILDRLAKRVFNVEGVARVQAPSRPDGAPIAHTS ::::::::*:**.:*:*:::::*: :: * *:: **: :**:* : ::: MSMEG_0381|M.smegmatis_MC2_155 IPFMLSMSNASQRLSLPFQQQRMEDLLKQADELTKNIALMKHMYALMQEM MAB_4116c|M.abscessus_ATCC_199 VPFMLSMSNASQRLSLPFQRARMDDMLKQADDMSKTIALMQRMSDLMNQM TH_3056|M.thermoresistible__bu IPFMLSMSQASQRLALPFQRARMDDMLKQADELTETIALMRRMQSLMEKM MAV_3248|M.avium_104 IPWIISMGQASQLQNMAFQKDRMNDMLVQANELGKMIGIMQHMLDLMREL Mb0458c|M.bovis_AF2122/97 IPFQISMQNAGQLQTIKYQRDRANDMLKQADEMATTIAVLTRMHSLMAEM Rv0450c|M.tuberculosis_H37Rv IPFQISMQNAGQLQTIKYQRDRANDMLKQADEMATTIAVLTRMHSLMAEM MMAR_0771|M.marinum_M IPFQISMQNAGQIQTLKYQRDRMNDMLTQAEEMAKTIALMRRMYGLMTQL MLBr_02378|M.leprae_Br4923 IPFQISMQNAGQVQTMKYQKDRMNDLLRQAENMAETIASMRRMHQLMALL MUL_0757|M.ulcerans_Agy99 IPFLISMQGTSQKLTEKYNQDLTTSMLQQVNDIQTNIDQMERMHDLTQQM Mflv_2705|M.gilvum_PYR-GCK IPFLISMQGVGQQQNMKLMQDRMDDMRTQADNLGKTLGTMRTMYGLMTRL Mvan_3833|M.vanbaalenii_PYR-1 IPFLISMQGVGQQQNMKLMKDRIADMRVQADDIGETIATMKTMYGLMTKF :*: :** ..* : .: *.::: : : * * : MSMEG_0381|M.smegmatis_MC2_155 VATTHSTVETTHEVQQTTKDLRDSIEDFQDFWRPIRNYLYWEPHCYDIPL MAB_4116c|M.abscessus_ATCC_199 VDTTHRMVSTTKDLQQDMRTLRDHIEDFEDFWRPIRNYFYWDKHCFDIPI TH_3056|M.thermoresistible__bu VATTHSMVGTTHELLDTTRDLRDHIADFDDFFRPIRNYFHWEPHCYNIPI MAV_3248|M.avium_104 VATTHHMVQTTHEMQEITGELRDHISDFEDFWRPLRSYFYWEKHCYDIPI Mb0458c|M.bovis_AF2122/97 ASTTHRMVGDTEEMKEITEELRDHVADFDDFWRPIRSYFYWEKHCYGIPI Rv0450c|M.tuberculosis_H37Rv ASTTHRMVGDTEEMKEITEELRDHVADFDDFWRPIRSYFYWEKHCYGIPI MMAR_0771|M.marinum_M ANNTHKMVGDTIEMQQITKELRDHIANFDDFFRPIRSYFYWEKHCYDIPI MLBr_02378|M.leprae_Br4923 TENTHHILNDTVEMQKTTSKLRDEIANFDDFWRPIRSYFYWERHCFNIPI MUL_0757|M.ulcerans_Agy99 ADVTHQMVIQMKGMVVDVEELRNHIADFDDFFRPIRSYFYWEKHCFDIPV Mflv_2705|M.gilvum_PYR-GCK SEVTTVMIDDFTEMQQTVHQIRDMVANFDDQFRPVRNYFYWEPHCYNIPL Mvan_3833|M.vanbaalenii_PYR-1 SNITTVMIDDMTEMRDTVHQIRDMVATFDDQFRPIRNYFYWEPHCYNIPL * : : :*: : *:* :**:*.*::*: **:.**: MSMEG_0381|M.smegmatis_MC2_155 CWSIRSLFDGLDGINEVTDKMGDLVEDLDHLDTLMPQMLLQFPPMIAMLE MAB_4116c|M.abscessus_ATCC_199 CWSIRSIFDALDGVDQVTDKMQTLVGDLDELDKLMPQLLEQFPIMIETMK TH_3056|M.thermoresistible__bu CWSIRSIFDALDGINEMTEKMEELVEDMDRLDALMPQMLVQFPQMIETME MAV_3248|M.avium_104 CFSLRSIFDALDGVDEINDKLGDLVKNLDQLDAILPQLVMQIPPMIETMS Mb0458c|M.bovis_AF2122/97 CWSFRSIFDALDGIDKLSEQIGVLLGDLREMDRLMPQMVAQIPPQIEAME Rv0450c|M.tuberculosis_H37Rv CWSFRSIFDALDGIDKLSEQIGVLLGDLREMDRLMPQMVAQIPPQIEAME MMAR_0771|M.marinum_M CSSFRSIFDALDGIDQIDEKLDNLVVDIKELDRLMPQMIETFPPMIETME MLBr_02378|M.leprae_Br4923 CWSFRSIFDALDGVDQIDERLNSIVGDIKNMDLLMPQMLEQFPPMIESME MUL_0757|M.ulcerans_Agy99 CWSLRSVFDTLDGVDLMTEDINNLLPLMERLDTLMPQMTAMMPEMIQTMK Mflv_2705|M.gilvum_PYR-GCK CWSFRSLFDSMDGISTMTESFDKALVNMETMRSLLPQMLATFPPMIETME Mvan_3833|M.vanbaalenii_PYR-1 CWSFRSLFDSMDGISVMTDTFDKAVANMDEMKALLPQMLATFPPMIETME * *:**:** :**:. : : : : : : ::**: :* * :. MSMEG_0381|M.smegmatis_MC2_155 NSRSMILTMHSTMSGIFSQMDDSTDNATAMGKAFDAARNDDSFYLPPDIL MAB_4116c|M.abscessus_ATCC_199 STRESMLTMHSTMSGIFAQMDESTENSTAMGKAFDASKNDDSFYLPPDVL TH_3056|M.thermoresistible__bu SSRTMILTMHATMSGIFDQMESSSENATAMGKAFDASHNDDSFYLPPEAL MAV_3248|M.avium_104 GMRTMMLTMHSTMSGVIGQMDSSAKDPSAMGQAFDASRNDDSFYLPPGII Mb0458c|M.bovis_AF2122/97 NMRTMILTMHSTMTGIFDQMLEMSDNATAMGKAFDAAKNDDSFYLPPEVF Rv0450c|M.tuberculosis_H37Rv NMRTMILTMHSTMTGIFDQMLEMSDNATAMGKAFDAAKNDDSFYLPPEVF MMAR_0771|M.marinum_M SMRLMMLTMHSTMSGLYDQMSEMSENANAMGKAFDAAKNDDSFYLPPEVF MLBr_02378|M.leprae_Br4923 SMRTIMLTMHSTMSGIFDQMNELSDNANTMGKAFDTAKNDDSFYLPPEVF MUL_0757|M.ulcerans_Agy99 SMKAQMLSMHSTQQGLQDQMAAMQEDSSAMGEAFDSSRNDDSFYLPPEVF Mflv_2705|M.gilvum_PYR-GCK SMRQMMLTTYATMGGFYDQMDELTQDSTEMGKAFDEAKNDDSFYLPPEVF Mvan_3833|M.vanbaalenii_PYR-1 SMRQMMLTTYATMGGFYDQMDELTRDSTEMGKAFDAAKNDDSFYLPPEVF . : :*: ::* *. ** :.. **:*** ::********* : MSMEG_0381|M.smegmatis_MC2_155 ENED-FKRVMKIFMSPDGKAARMLITQRGDPATPEGIALVEPIRVAAEEA MAB_4116c|M.abscessus_ATCC_199 KNKD-FQRVMKIFMSPDGKSSRMLISQRGDPATPEGISRVEPIKTAAEEA TH_3056|M.thermoresistible__bu ENKD-FQRVMEIFLSPDGKAARMLVTQRGDPATPEGMALVEPIYIAAEEA MAV_3248|M.avium_104 NGSDSFKRVEKVFMSPDGKDVRLLITQRGDPATPEGLSRVEQIKTAAEES Mb0458c|M.bovis_AF2122/97 KNKD-FQRAMKSFLSSDGHAARFIILHRGDPQSPEGIKSIDAIRTAAEES Rv0450c|M.tuberculosis_H37Rv KNKD-FQRAMKSFLSSDGHAARFIILHRGDPQSPEGIKSIDAIRTAAEES MMAR_0771|M.marinum_M KNED-FKRAMKSFLSPDGHAARFIILHRGDPQSAQGIASIDQIRTAAEES MLBr_02378|M.leprae_Br4923 KNTD-FKRAMKSFLSSDGHAARFIILHRGDPASVAGIASINAIRTAAEEA MUL_0757|M.ulcerans_Agy99 NNPD-FKRGLEQFLSPDGHAVRFIISHEGDPMSQAGINHIDKIKTAAKEA Mflv_2705|M.gilvum_PYR-GCK ENED-FKRAMESFFSPDGKTVRMLVSHRGDPTTPEALARVEPIKIAAIEA Mvan_3833|M.vanbaalenii_PYR-1 ENED-FKRAMESFFSPDGKTVRMLIAHRGNPTTDEALQRVEPIKIAAIEA :. * *:* : *:*.**: *::: :.*:* : .: :: * ** *: MSMEG_0381|M.smegmatis_MC2_155 LKGTPLESAELHLAGTAAGVKDLVDGSKIDLLIAGVAALCLIFIIMLIMT MAB_4116c|M.abscessus_ATCC_199 LKGTPLEHAKLSLAGTAAGVSELVEGSKYDLLIAGVAALCLIFIIMLLMT TH_3056|M.thermoresistible__bu LKGTPLESSRIYLAGSAAGVKDLVEGAKYDLMIAAISAVCLIFMIMVFMT MAV_3248|M.avium_104 LKGTPLENSKIYLTGTAAITKDLVDGSKFDLLIAGVSALCLIFIIMLIMT Mb0458c|M.bovis_AF2122/97 LKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAISSLCLIFIIMLIIT Rv0450c|M.tuberculosis_H37Rv LKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAISSLCLIFIIMLIIT MMAR_0771|M.marinum_M LKGTPLEDAKIYVAGTASVFKDISEGADWDLLIAGISSLCLIFIIMLILT MLBr_02378|M.leprae_Br4923 LKGTPLEDTKIYLAGTAAVFKDIDEGANWDLVIAGISSLCLIFIIMLIIT MUL_0757|M.ulcerans_Agy99 IKGTPLEGSTIYLGGTVAMFKDLSDGNTFDLMIAGISALCLIFIIMLIIT Mflv_2705|M.gilvum_PYR-GCK LKGTPLENAQIQLGGTAATFKDMSDGSRYDMMIAILSALCLVLVIMLVLT Mvan_3833|M.vanbaalenii_PYR-1 LKGTPLENAQIQLGGTAATFKDMSDGSRYDLLIAVISALCLVLMIMLVLT :****** : : : *:.: :: :* *::** ::::**:::**:.:* MSMEG_0381|M.smegmatis_MC2_155 RSFIAALVIVGTVAMSLGASFGLSVLVWQHLLGIQINWVVLAMSVIVLLA MAB_4116c|M.abscessus_ATCC_199 RSLVAALVIVGTVALSLGASFGLSVLVWQHICGIQINWVVLAMSVIVLLA TH_3056|M.thermoresistible__bu RSVIAALVIVGTVVLSLGASFGMSVLLWQHLLGIQLHWVVLAMSVIVLLA MAV_3248|M.avium_104 RSFIAAMVIVGTVLLSLGASFGLSVLVWQYLLHMQLHWTVLSTSVIVLLA Mb0458c|M.bovis_AF2122/97 RAFIAAAVIVGTVALSLGASFGLSVLLWQHILAIHLHWLVLAMSVIVLLA Rv0450c|M.tuberculosis_H37Rv RAFIAAAVIVGTVALSLGASFGLSVLLWQHILAIHLHWLVLAMSVIVLLA MMAR_0771|M.marinum_M RAFVAAAVIVGTVALSLGASFGMSVLLWQHILNIDLHYMVLAMSVIVLLA MLBr_02378|M.leprae_Br4923 RAFVAAAVIVGTVALSLGASFGLSVLLWQHILGIELHYLVLAMSVIVLLA MUL_0757|M.ulcerans_Agy99 RSVVAAAVIVGTVVLSLGASFGLSVLIWQHVLGIELHWLVLAMAVIILLA Mflv_2705|M.gilvum_PYR-GCK RSLVAAVVIVGTVALSLGASFGVSVLIWQHLLGVELHWMVLVMSIIALIA Mvan_3833|M.vanbaalenii_PYR-1 RSLVAALVIVGTVTLSLGASFGISILIWQHIVGIELHWMVLALSIIALIA *:.:** ****** :*******:*:*:**:: :.::: ** ::* *:* MSMEG_0381|M.smegmatis_MC2_155 VGSDYNLLLVSRMKEEIGAGLNTGIIRAMGGTGKVVTAAGLVFAATMASM MAB_4116c|M.abscessus_ATCC_199 VGSDYNLLLVSRMKEELGAGLKTGIIRAMGGTGKVVTAAGLVFAATMGSM TH_3056|M.thermoresistible__bu VGSDYNLMLVSRMKEEIGAGLNTGIIRAMGGTGRVVTMAGLVFAATMASM MAV_3248|M.avium_104 VGSDYNLLLVSRMKEELAAGIHTGIIRAMGGTGKVVTNAGLVFAFTMGAM Mb0458c|M.bovis_AF2122/97 VGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVVTNAGLVFAVTMASM Rv0450c|M.tuberculosis_H37Rv VGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVVTNAGLVFAVTMASM MMAR_0771|M.marinum_M VGSDYNLLLVSRFKEEIPAGLKTGIIRAMGGTGKVVTNAGLVFAFTMASM MLBr_02378|M.leprae_Br4923 VGSDYNLLLVSRFKQEIQAGLKTGIIRSMGGTGKVVTNAGLVFAFTMASM MUL_0757|M.ulcerans_Agy99 VGADYNLLLVARLKEEIHAGINTGIIRAMGGSGSVVTAAGLVFAFTMMSF Mflv_2705|M.gilvum_PYR-GCK VGSDYNLLLVSRFKEEIGAGIKTGIIRAIGGTGSVVSVAGVVFALTMASM Mvan_3833|M.vanbaalenii_PYR-1 VGSDYNLLLVSRFKEEIPAGIKTGIIRAIGGTGSVVTVAGVVFALTMASM **:****:**:*:*:*: **::*****::**:* **: **:*** ** :: MSMEG_0381|M.smegmatis_MC2_155 IVSDLLTIGQVGTTIGLGLLFDTLVVRAFMTPSIAALLGRWFWWPQRVRQ MAB_4116c|M.abscessus_ATCC_199 IVSDLLTIGQVGTTIGLGLLFDTLIVRAFMTPAIAALLGRWFWWPLQVSP TH_3056|M.thermoresistible__bu IVSDLLMIGQVGTTIALGLLFDTMVVRAFMTPSVAAILGRWFWWPQRVRT MAV_3248|M.avium_104 VVSDLRSIGQVGTTIGLGLLFDTLIVRAFMTPSVAALLGRWFWWPQLVRP Mb0458c|M.bovis_AF2122/97 AVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAALLGRWFWWPLRVRS Rv0450c|M.tuberculosis_H37Rv AVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAALLGRWFWWPLRVRS MMAR_0771|M.marinum_M AVSDLRVIGQVGTTIGLGLLFDTLIVRAFMTPSIAALLGRWFWWPMRVRT MLBr_02378|M.leprae_Br4923 VVSDLRVIGQVGTTIGLGLLFDTLIVRSFMMPSIAALLGRWFWWPQQGRT MUL_0757|M.ulcerans_Agy99 AVSELTVMAQVGTTIGMGLLFDTLIVRSFMTPSIAALLGKWFWWPQVVRQ Mflv_2705|M.gilvum_PYR-GCK VVSDLKVIAQVGTTIGLGLLFDTFIVRAFMMPSIATLLGRWFWWPLVVRS Mvan_3833|M.vanbaalenii_PYR-1 VVSDLRVMAQVGTTIGLGLLFDTFIVRAFMMPAIATLLGRWFWWPLVVRS **:* :.******.:******::**:** *::*::**:***** MSMEG_0381|M.smegmatis_MC2_155 RPASAMLRSVGPRPLVRSLLLRD---- MAB_4116c|M.abscessus_ATCC_199 RPVGAVRGWRGPR-LVRSVLQRN---- TH_3056|M.thermoresistible__bu RPASAMLRPVGPRPLVRSLLLRD---- MAV_3248|M.avium_104 RPASTMLRPTGPRPLVRSLLLKQPQ-- Mb0458c|M.bovis_AF2122/97 RPARTPTVPSETQPAGRPLAMSSDRLG Rv0450c|M.tuberculosis_H37Rv RPARTPTVPSETQPAGRPLAMSSDRLG MMAR_0771|M.marinum_M RPARTPSSPTADPEPDRALAMSGER-- MLBr_02378|M.leprae_Br4923 RPLLTVAAPVG-LPPDRSLVYSD---- MUL_0757|M.ulcerans_Agy99 RPAPQPWPTPAPTPPPATTSV------ Mflv_2705|M.gilvum_PYR-GCK RPLRPRPQQQALGVGGQQG-------- Mvan_3833|M.vanbaalenii_PYR-1 RPLRLPPRT------------------ **