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M. avium 104 MAV_5062 (-)

annotation: pyruvate, water dikinase
coordinates: 5211213 - 5212382
length: 389

MTREVASWWRYATSAPGLARPVDQQFAQAFKMLEYAMRVHVTETFVAQGIFDALGKLAESAGRPGLHLEL
STGYGQMVETELVAALHEVAQGRAEMAEFLARYGYRCAGEIEVSNPSWRERPELVKRMVDKYKAAPTRKN
LAAAATARTRARQQAERELLAALPRWKRPLGRLLIKLAATFIPLREEGKSALAMAFDGARAACGIRGAEL
AAAGVVDRSEDVFYLTIDEIRGTPPAEARALIARRRELRAAYEQIDVPDAWIGPPVAVSVANSGNSRVGS
LSGVAAAHGVAEGPARVLASADDLDDLEPDEILVCRTTDPSWASAFHLAAGAVIDIGSTSSHGAIIAREM
GMPCVIGTGNGTQLLRTGDFIRVDGSTGIVTVLQEAKRA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_5062--100% (389)pyruvate, water dikinase
M. avium 104MAV_1955-6e-6937.27% (381) PEP-utilizing protein
M. avium 104MAV_5056-9e-6238.07% (394) PEP-utilizing protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2073c-3e-3129.79% (339) hypothetical protein Mb2073c
M. gilvum PYR-GCKMflv_0493-3e-3435.25% (295) pyruvate, water dikinase
M. tuberculosis H37RvRv2047c-3e-3129.79% (339) hypothetical protein Rv2047c
M. leprae Br4923MLBr_00955ppdK2e-0734.00% (100) pyruvate phosphate dikinase
M. abscessus ATCC 19977-----
M. marinum MMMAR_3024-9e-3330.45% (335) hypothetical protein MMAR_3024
M. smegmatis MC2 155MSMEG_3934-7e-2039.68% (126) phosphoenolpyruvate synthase
M. thermoresistible (build 8)TH_4230-1e-2627.39% (314) PUTATIVE putative phosphoenolpyruvate synthase
M. ulcerans Agy99MUL_2265-2e-3330.45% (335) hypothetical protein MUL_2265
M. vanbaalenii PYR-1Mvan_1818-2e-3132.55% (298) pyruvate, water dikinase

CLUSTAL 2.0.9 multiple sequence alignment


Mb2073c|M.bovis_AF2122/97           MRIAVTGASGVLGRGLTARLLSQGHEVVGIARHRPDSWPSSADFIAADIR
Rv2047c|M.tuberculosis_H37Rv        MRIAVTGASGVLGRGLTARLLSQGHEVVGIARHRPDSWPSSADFIAADIR
MMAR_3024|M.marinum_M               MRVAVTGAGGVLGRGLASRLLSQGHEVVGMSRRRPDSWPSQADFVAGDIR
MUL_2265|M.ulcerans_Agy99           MRVAVTGAGGVLGRGLASRLLSQGHEVVGMSRRRPDSWPSQADFVAGDIR
Mflv_0493|M.gilvum_PYR-GCK          -------------------MFDASSRIVDLADVLDDSFGGKALGLAELTR
Mvan_1818|M.vanbaalenii_PYR-1       ----------------------MAPATIEFDDVTDDRFGGKAAGLAELRR
MAV_5062|M.avium_104                --------------------------------------------------
TH_4230|M.thermoresistible__bu      --------------------MSYIVEFSEPAAVQRAVAGGKGAHLASLTT
MSMEG_3934|M.smegmatis_MC2_155      ---------------MDIMSDRYVRTLDILTIADAEEAGGKGANLGELVA
MLBr_00955|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2073c|M.bovis_AF2122/97           DATAVESAMTGADVVAHCAWVRGR------NDHINIDGTANVLKAMAETG
Rv2047c|M.tuberculosis_H37Rv        DATAVESAMTGADVVAHCAWVRGR------NDHINIDGTANVLKAMAETG
MMAR_3024|M.marinum_M               DAAAVRRAITGADVVAHCAWARNPGPDGRISQQINIDGTRNVLDAMAACG
MUL_2265|M.ulcerans_Agy99           DAAAVRRAITGADVVAHCAWARNPGPDGRISQQINIDGTRNVLDAMAACG
Mflv_0493|M.gilvum_PYR-GCK          LGLPVPPGFVIADASGTS----------------LGDAVTERFSRMRAAG
Mvan_1818|M.vanbaalenii_PYR-1       IGLSVPVGFVIADASAHG----------------ALDAAVDRFCQMAAEG
MAV_5062|M.avium_104                --------------------------------------------------
TH_4230|M.thermoresistible__bu      AGFTVPPGFVVTVDAFDAAVTRNIG------ADVEKILAGTDFADADAVE
MSMEG_3934|M.smegmatis_MC2_155      ADLPVPHGFVVMRSAYLDSVRMGG---VEAELAALHTEALTHAADTARLS
MLBr_00955|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2073c|M.bovis_AF2122/97           TGRIVFTSS-------------------------GHQPRVEQMLADCGLE
Rv2047c|M.tuberculosis_H37Rv        TGRIVFTSS-------------------------GHQPRVEQMLADCGLE
MMAR_3024|M.marinum_M               TGRIVFPSSPHVYRPGVPMPATEHGAVAPASAEGRHKAGVEQMLQESGAQ
MUL_2265|M.ulcerans_Agy99           TGRIVFPSSPHVYRPGLPMPATEHGAVAPASAEGRHKAGVEQMLQESGAQ
Mflv_0493|M.gilvum_PYR-GCK          QTPVAVRSS--------------------------------AAGEDGAEH
Mvan_1818|M.vanbaalenii_PYR-1       VTPVAVRSS--------------------------------AVGEDGEDQ
MAV_5062|M.avium_104                --------------------------------------------------
TH_4230|M.thermoresistible__bu      EAAAKVRALVTDLDVPADIASAITAAYNKLGSDAAVAVRSSGTAEDMAEA
MSMEG_3934|M.smegmatis_MC2_155      ELCRRMQSLVNKAGLSPSVRDATLAAYRALGTDVVVAVRSSATGEDGRDA
MLBr_00955|M.leprae_Br4923          ----------------------------------------------MPGQ
                                                                                      

Mb2073c|M.bovis_AF2122/97           WVAVRCALIFGRN-VDNWVQRLFALPVLPAGYADRVVQVVHSDDAQRLLV
Rv2047c|M.tuberculosis_H37Rv        WVAVRCALIFGRN-VDNWVQRLFALPVLPAGYADRVVQVVHSDDAQRLLV
MMAR_3024|M.marinum_M               WVAVRSALIVGRN-IDNWVRRLFALPAFPDGSADDVLQVVHLDDVLRLLT
MUL_2265|M.ulcerans_Agy99           WVAVRSALIVGRN-IDNWVRRLFALPAFPDGSADDVLQVVHLDDVLRLLT
Mflv_0493|M.gilvum_PYR-GCK          SFAGQYDTVLG----VGSVDELTAAVEKCVRSAGSERAAAYQDGGAAARM
Mvan_1818|M.vanbaalenii_PYR-1       SFAGQYDTVLG----VASVDDFTAAVRRCAGSVASQRASSYS-GHSPATM
MAV_5062|M.avium_104                --------------------------------------------------
TH_4230|M.thermoresistible__bu      SFAGQYDTYLDVVGTTAVLDAVKRCWASLYTTRAVAYRSGKELDTSTVKL
MSMEG_3934|M.smegmatis_MC2_155      SFAGMNRTITNVMGEVALLDAVTQCWMSLFSPRVITYRASRGFTAAP-AM
MLBr_00955|M.leprae_Br4923          SHKEPHRRATSTPRSLKQATSELRWALSLAAPESPAFMRHLLGNAHDKVD
                                                                                      

Mb2073c|M.bovis_AF2122/97           RALLDTVIDSGPVNLAAPGELTFRRIAAALGRPMVPIGSPVLRRVTSFAE
Rv2047c|M.tuberculosis_H37Rv        RALLDTVIDSGPVNLAAPGELTFRRIAAALGRPMVPIGSPVLRRVTSFAE
MMAR_3024|M.marinum_M               RAVSDVGAGTGPVNLAAPGLPTLREIAMALRRPILPVG-AVLRRIGSVAE
MUL_2265|M.ulcerans_Agy99           RAVSDVGAGTGPVNLAAPGLPTLREIATALRRPILPVG-AALRRIGSVAE
Mflv_0493|M.gilvum_PYR-GCK          HLVVQQMVDARAAGVVFTADPTSGRRDLLVIDAVRGLGESLVDGSTASDH
Mvan_1818|M.vanbaalenii_PYR-1       HVVVQQMVDARAAGVVFTADPATGRRDLMVIDAIAGLGEALVDGSASPDH
MAV_5062|M.avium_104                --------------------------------------------------
TH_4230|M.thermoresistible__bu      AVVVQEMVEAEVSGVMFTANPFTTATDELVINASWGLGEGIVSGILTPDQ
MSMEG_3934|M.smegmatis_MC2_155      AVVVQQMLSADRAGVAFTSDPSTGDADHIVIEAAFGQGEVVVSGKVEPDT
MLBr_00955|M.leprae_Br4923          ITTSSEHVAAFTEHAIVLLNGNAHQTRELLGGKGYNINAMRRHQLAVPPA
                                                                                      

Mb2073c|M.bovis_AF2122/97           LELLHSAPLMDVTLLRD----------------------RWGFQPAWNAE
Rv2047c|M.tuberculosis_H37Rv        LELLHSAPLMDVTLLRD----------------------RWGFQPAWNAE
MMAR_3024|M.marinum_M               FQLVQGVPVMDTARLHD----------------------EWKFQPAFTAE
MUL_2265|M.ulcerans_Agy99           FQLVQGVPVMDTARLHD----------------------EWKFQPAFTAE
Mflv_0493|M.gilvum_PYR-GCK          FVLTHAG-----DTVTT----------------------EASSQPALADD
Mvan_1818|M.vanbaalenii_PYR-1       VVLNADG-----STAVR----------------------EVGTAPVLSSD
MAV_5062|M.avium_104                --------------------------------------------------
TH_4230|M.thermoresistible__bu      FTLDKADLTVRDVTIGPKEVRVVRNPETGQGTVTLDNDEASRARRTLDDA
MSMEG_3934|M.smegmatis_MC2_155      YVIDKRTLEVRDVRIGFKAIKIVRGDDGADSMVQLER--SQAEARVLDDD
MLBr_00955|M.leprae_Br4923          FCITTEVGVRYLAAPTP-------------------------TMEAIWND
                                                                                      

Mb2073c|M.bovis_AF2122/97           ECLEDFTLAVRGRIGLGKRTFSLPWRLANIQDLPAVDSPADDGVAPRLAG
Rv2047c|M.tuberculosis_H37Rv        ECLEDFTLAVRGRIGLGKRTFSLPWRLANIQDLPAVDSPADDGVAPRLAG
MMAR_3024|M.marinum_M               ESVEDFALAVRGRVSLGRRVVSLPWRLANIQDLPAVDAPAQDGVVPRLAG
MUL_2265|M.ulcerans_Agy99           ESVEDFALAVRGRVSLGRRVVSLPWRLANIQDLPAIDASAQDGVVPRLAG
Mflv_0493|M.gilvum_PYR-GCK          EIDRIRTGALLAAAHWG-RPLDLEWAIDRDGLLWWLQARPITTLP-----
Mvan_1818|M.vanbaalenii_PYR-1       DVAEIRSGALRAARHWG-RPLDLEWAIDGTGKLWWLQARPITTLP-----
MAV_5062|M.avium_104                --------------------------------------------------
TH_4230|M.thermoresistible__bu      ALVRLGDIGRRIEEHFDSLPQDVEWAYAD-DTFYVLQSRAVTGVDFT---
MSMEG_3934|M.smegmatis_MC2_155      ALRKIATLAVATETHNG-CPQDIEWVIAD-GAVWLVQARPITTLG-----
MLBr_00955|M.leprae_Br4923          VLDQMRWLEAETSRTFGWGPRPLLVSIRS---------------------
                                                                                      

Mb2073c|M.bovis_AF2122/97           PEGANGEFDTPIDPRFPTYLATNLSEALPGPFSPSSASVTVRGLRAGGVG
Rv2047c|M.tuberculosis_H37Rv        PEGANGEFDTPIDPRFPTYLATNLSEALPGPFSPSSASVTVRGLRAGGVG
MMAR_3024|M.marinum_M               PEGVNGEFDTPIDPRFPTFLATNLSEALPGPFSPSSASVTVRGLRAGGVG
MUL_2265|M.ulcerans_Agy99           PEGVNGEFDTPIDPRFPTFLATNLSEALPGPFSPSSASVTVRGLRAGGVG
Mflv_0493|M.gilvum_PYR-GCK          --GDPNEMDTPVTGPTHVYTRCNIGEMMPGAFCPLTASVSGHAIDY-AMQ
Mvan_1818|M.vanbaalenii_PYR-1       --GDLNEMDSPVAGSDHVYTRCNIGEMMPGAFCPLTASVSGYAIDY-AMQ
MAV_5062|M.avium_104                --------------------------------------------------
TH_4230|M.thermoresistible__bu      WDDDVDAWQWSRPHADTIWTRGFADEYWTGAITPLFYSVRGAEQTSSYQR
MSMEG_3934|M.smegmatis_MC2_155      ----SAGSTAGDEPSVLIRGLPAAPGVASGRVRVLLAPDDGDKLTDGEIL
MLBr_00955|M.leprae_Br4923          --GAVQSMPGMMDTILNLGINDPVEQALAAASPSPIPQTFARDTRLRFIR
                                                                                      

Mb2073c|M.bovis_AF2122/97           IAERLRPSGVIQREIAMRTVAVFAHRLYGAITSAHFMAATVPFAKPATIV
Rv2047c|M.tuberculosis_H37Rv        IAERLRPSGVIQREIAMRTVAVFAHRLYGAITSAHFMAATVPFAKPATIV
MMAR_3024|M.marinum_M               IAERLRPGGVIQREIAMRTVAVFAHRLYGAITSAHFMAETVPFAKPAMIV
MUL_2265|M.ulcerans_Agy99           IAERLRPGGVIQREIAMRTVAVFAHRLYGAITSAHFMAETVPFAKPAMIV
Mflv_0493|M.gilvum_PYR-GCK          MVQVAGGVQERYEDRARQVGYFFGHMFLNMTEGTALSSGILGNSLEQFSL
Mvan_1818|M.vanbaalenii_PYR-1       MTQVVARAQPRYEKPWLQVGYFYGHMFLNLTEGTALSSGILGNSREQFSM
MAV_5062|M.avium_104                ---------------MTREVASWWRYATSAPGLARPVDQQFAQAFKMLEY
TH_4230|M.thermoresistible__bu      SAKLWG---ADRLAALPQFKYHKAEVYFNVENQEEFLRYTCPPMFRAAAS
MSMEG_3934|M.smegmatis_MC2_155      VAPTTNPDWLPTIRRAAALVTETGGMTCHAAIVARELGVPCVVGARSATV
MLBr_00955|M.leprae_Br4923          TYRRIVDPLNPPPANTYDQLRAAIESIFSSWNSPRAVAYRTHYGLDDQSG
                                                                                      

Mb2073c|M.bovis_AF2122/97           SNSGFFGPSMASLPIFGAQRPPSESS-RARRWLRTLRNIGVFGVNLVGLS
Rv2047c|M.tuberculosis_H37Rv        SNSGFFGPSMASLPIFGAQRPPSESS-RARRWLRTLRNIGVFGVNLVGLS
MMAR_3024|M.marinum_M               SNSGFFGPSMGSLPIFGEERPPAESS-FVRRQLRTVRNIGVFGVNLVGLS
MUL_2265|M.ulcerans_Agy99           SNSGFFGPSMGSLPIFGEERPPAESS-FVRRQLCTVRNIGVFGVNLVGLS
Mflv_0493|M.gilvum_PYR-GCK          SVCGRVIDELEPGPPKPFVRKLINTVRLSTFALSSAPAIRRLPQTIAAFP
Mvan_1818|M.vanbaalenii_PYR-1       SICGRVVDELEAKPPRPFARKLVNTVRLTSHALSAGPAIRRLADQIAGWP
MAV_5062|M.avium_104                AMRVHVTETFVAQGIFDALGKLAESAGRPGLHLELSTGYG----------
TH_4230|M.thermoresistible__bu      GYLPPSRAAAVAEDPFSWAGYAKIHARILGLDITQSFHKWIASVEDYMQN
MSMEG_3934|M.smegmatis_MC2_155      ALAVGSMVTVDGTRGEVTTGRLPETVRTTTTPQEPAPHITG---------
MLBr_00955|M.leprae_Br4923          TAVIVQAMVFGNQGAYSGAGTLFSRNPITRESKLFGEWLPG---------
                                                                                      

Mb2073c|M.bovis_AF2122/97           AGSPRDTDAYVADVDRLERLAFDNLATHDDRRLLSLILLARDHVVHGWVL
Rv2047c|M.tuberculosis_H37Rv        AGSPRDTDAYVADVDRLERLAFDNLATHDDRRLLSLILLARDHVVHGWVL
MMAR_3024|M.marinum_M               AGSALDTNDFIADVDRLEQLAGGDVTTLDDRRLLSLILLARDHVVHGWVL
MUL_2265|M.ulcerans_Agy99           AGSALDTNDFIADVDRLEQLAGGDVTTLDDRRLLSLILLARDHVVHGWVL
Mflv_0493|M.gilvum_PYR-GCK          PITSRDPAVVLRHLE-------AGVDIYREVTLIHVRSSSRSAVAANVLE
Mvan_1818|M.vanbaalenii_PYR-1       IPSHEDARLVLQQLE-------SGVQLYCDVTLTHVRSSSRAAVAANILE
MAV_5062|M.avium_104                -------------------------QMVETELVAALHEVAQGRAEMAEFL
TH_4230|M.thermoresistible__bu      RIEEADGLGDEELRKLTDRALQKYIDDRMEFVEGLLYNMWSGFQIHASLV
MSMEG_3934|M.smegmatis_MC2_155      ------------------------EATGTKVYVNLAMPDSAEAVAAQDVD
MLBr_00955|M.leprae_Br4923          -------------------------GQGDDVVSGLVEVQPITSLRDEQPT
                                                                                      

Mb2073c|M.bovis_AF2122/97           ASGSFMLCAAFNVLLRGLCGRDTAPAAGPELVSARSVEAVQRLVAAARRD
Rv2047c|M.tuberculosis_H37Rv        ASGSFMLCAAFNVLLRGLCGRDTAPAAGPELVSARSVEAVQRLVAAARRD
MMAR_3024|M.marinum_M               ASGSFMLCAAFNVLLRAVSGRDTAPAAGPELVSARSVEAVQRLVAAARHD
MUL_2265|M.ulcerans_Agy99           ASGSFMLCAAFNVLLRAVSGRDTAPAAGPELVSARSVEAVQRLVDAARHD
Mflv_0493|M.gilvum_PYR-GCK          SHLVRRAAKRGASDTAGSAEAIRLMTGAG-VESALMVEELTAVVSMLRRD
Mvan_1818|M.vanbaalenii_PYR-1       STLVRQAVKNGRSEEEGQAEAARLMAGASDVESAMMLDQLQSVVRAIAAD
MAV_5062|M.avium_104                ARYGYRCAGEIEVSNPSWRER---------------PELVKRMVDKYKAA
TH_4230|M.thermoresistible__bu      LNGLGTLLAKWYDGDNQMIFVDLITGLPQRTITLQENLDLWDLAAEIRRS
MSMEG_3934|M.smegmatis_MC2_155      GVGLLRAEFMLTEALAGRHPRDLITKGEQDTLVDAMAAAVTRIGTAFAPR
MLBr_00955|M.leprae_Br4923          VYDELVDTAGRLERLGSDVQEIEFTTEDSKLWLLQTRVAERSAQVAVRLA
                                                                                      

Mb2073c|M.bovis_AF2122/97           PVVIR--LLAEPGERLDKLAVEAP--EFHSAVLAELTLIGHRGPAEVEMA
Rv2047c|M.tuberculosis_H37Rv        PVVIR--LLAEPGERLDKLAVEAP--EFHSAVLAELTLIGHRGPAEVEMA
MMAR_3024|M.marinum_M               EAVIR--LLSEPGDRLGKLAVAAP--HFYDAVRQELSLIGHRGPAEVEMM
MUL_2265|M.ulcerans_Agy99           EAVIR--LLSEPGDRLGKLAVAAP--HFYDAVRQELSLIGHRGPAEVEMM
Mflv_0493|M.gilvum_PYR-GCK          GDAAARFLAAPAGEAVTRLRAAET--PSGAALRTFLDRHGHRGYRELCMR
Mvan_1818|M.vanbaalenii_PYR-1       SGVATRFLAAAPDVAVVELQRADN--ASGEALRQFLLRHGHRGYRELCMR
MAV_5062|M.avium_104                PTRKN--LAAAATARTRARQQAER--ELLAALPRWKRPLG----------
TH_4230|M.thermoresistible__bu      PALRKLFEQSEPHEFFDKLAVHPDGAEAHRRYQQLLKDHGHRGHADRDFI
MSMEG_3934|M.smegmatis_MC2_155      PVIYR--AMDFRTNEFRGLAGGEQ-----FEPVEHNPMIGYRGCYR----
MLBr_00955|M.leprae_Br4923          LQLWQEGLIDDAEALRRVTPVHVET-------------------------
                                                                                      

Mb2073c|M.bovis_AF2122/97           ATSYADNPELLVRMVAKTLRAVP--------------------------A
Rv2047c|M.tuberculosis_H37Rv        ATSYADNPELLVRMVAKTLRAVP--------------------------A
MMAR_3024|M.marinum_M               STSYADNPELLVGMVAKTLSTSS--------------------------V
MUL_2265|M.ulcerans_Agy99           STSYADNPELLVGMVAKTLSTSS--------------------------V
Mflv_0493|M.gilvum_PYR-GCK          DPSWADDPDGLGAMMQVMLRGAAPENPA---------------------A
Mvan_1818|M.vanbaalenii_PYR-1       DPSWAQDAGGLGAMMQVMVRAASSDRQP---------------------A
MAV_5062|M.avium_104                --------------------------------------------------
TH_4230|M.thermoresistible__bu      FPRRIEDPSIDYRSLQALLSGDGMQRPDEQERKQAAKREAATADVIARLE
MSMEG_3934|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_00955|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2073c|M.bovis_AF2122/97           PQPPTPVIPLRAKPVALLAARQLRDREVRRDRMVRAIWVLRALLREYGRR
Rv2047c|M.tuberculosis_H37Rv        PQPPTPVIPLRAKPVALLAARQLRDREVRRDRMVRAIWVLRALLREYGRR
MMAR_3024|M.marinum_M               PQPPQPSIPLQAKPIAVLAARQLRDREARRDKMVRAIWVLRALLREHGRR
MUL_2265|M.ulcerans_Agy99           PQPPQPSIPLQAKPIAVLAARQLRDREARRDKMVRAIWVLRALLREHGRR
Mflv_0493|M.gilvum_PYR-GCK          TAPSDPAQSRTLRVLARLAQAGARGREETKSRMALMAHLLKRGYRHLGEV
Mvan_1818|M.vanbaalenii_PYR-1       HSPTEAPTSPAIRFLARLAQGGARGREETKSKMALMAHALKRGYRHLGEV
MAV_5062|M.avium_104                ------------RLLIKLAATFIPLREEGKSALAMAFDGARAACGIRGAE
TH_4230|M.thermoresistible__bu      AKPFGRLRADLFRMLLDYAHRFMVLRDDERHYVDRATMSKKRAFLELGRR
MSMEG_3934|M.smegmatis_MC2_155      -------YIKEPDLFALELSALARAREHTPNIHLMIPFVRTRWELEECLA
MLBr_00955|M.leprae_Br4923          -----------VLLPVLQPENHLSATLLAKGTPTCPGVISGKAYTEVDEA
                                                                                      

Mb2073c|M.bovis_AF2122/97           LTEAGVFDTPDDVFYLLV-DEIDALP-------ADVSGLVARRRAEQRRL
Rv2047c|M.tuberculosis_H37Rv        LTEAGVFDTPDDVFYLLV-DEIDALP-------ADVSGLVARRRAEQRRL
MMAR_3024|M.marinum_M               LAEAGVLHASDDVFYLLV-DELDALP-------ADVAELVARRRAEQRRL
MUL_2265|M.ulcerans_Agy99           LAEAGVLHASDDVFYLLV-DEVDALP-------ADVAELVARRRAEQRRL
Mflv_0493|M.gilvum_PYR-GCK          LHEAGRLPDADLVFFFDR-RELPLVVSG--DDVTELVHRARQRREALPFQ
Mvan_1818|M.vanbaalenii_PYR-1       LARSGRLPDADLVFFFDR-SELPRVVGD--DDISELVQSAVKRREALAYQ
MAV_5062|M.avium_104                LAAAGVVDRSEDVFYLTI-DEIRGTPP------AEARALIARRRELRAAY
TH_4230|M.thermoresistible__bu      LLARDLIERLDDVYFLTK-DELYELMAERAPQALVRAKIAGRRKQFEAFD
MSMEG_3934|M.smegmatis_MC2_155      LVDASPLRRHRNLHRWVM-AEVPSVVH------------------WLPEY
MLBr_00955|M.leprae_Br4923          LDAAESAEQVILVRDHTRPDDVLGMLAS---------------QGVVTEV
                                    *           :       ::                            

Mb2073c|M.bovis_AF2122/97           AGIVPPTVFSGS---WEPSPSSAAALAAGDTLRGVGVCGGRVRGRVRIVR
Rv2047c|M.tuberculosis_H37Rv        AGIVPPTVFSGS---WEPSPSSAAALAAGDTLRGVGVCGGRVRGRVRIVR
MMAR_3024|M.marinum_M               TAVVPPTVFSGK---WEPSTASAAALTAGGTLRGVGVCGGRVRGRVRIVR
MUL_2265|M.ulcerans_Agy99           TAVVPPTVFSGK---WEPSTASAAALTAEGTLRGVGVCGGRVRGRVRIVR
Mflv_0493|M.gilvum_PYR-GCK          AALEFGDVSVGR---PTPIVR--AAVSGDGVVAGRPAGHGSVEGVVRVAR
Mvan_1818|M.vanbaalenii_PYR-1       DSLEFEDVSVGR---PRPVVAPPVITSTADQVVGRPASRGTVEGTVRVAK
MAV_5062|M.avium_104                EQIDVPDAWIGP---PVAVSVANSGNSRVGSLSGVAAAHGVAEGPARVLA
TH_4230|M.thermoresistible__bu      RKDAIPPMYLQHGREWIDPTEISGGDVDPRALQGLPTSPGTVEGRARVVR
MSMEG_3934|M.smegmatis_MC2_155      VGMGIDGVSIGS----NDLTQLMLGVDRDSETCAELFDESDAAVLDAISR
MLBr_00955|M.leprae_Br4923          GGAASHAAVVSR--ELSRVAVVGCGQGTAVSLAGKQITVDGDKGEVRQGN
                                                                     .     .          

Mb2073c|M.bovis_AF2122/97           --PETIDDLQPGEILVAEVTDVGYTAAFCYAAAVVTELGGPMSHAAVVAR
Rv2047c|M.tuberculosis_H37Rv        --PETIDDLQPGEILVAEVTDVGYTAAFCYAAAVVTELGGPMSHAAVVAR
MMAR_3024|M.marinum_M               --PETIDELEPGEILVAEVTDVGYTAAFCYAAAVVTELGGPMSHAAVVAR
MUL_2265|M.ulcerans_Agy99           --PETIDELEPGEILVAEVTDVGYTAAFCYAAAVVTELGGPMSHAAVVAR
Mflv_0493|M.gilvum_PYR-GCK          S-VVEARDLQPGEILVAPVTDVGWTPYFAVIAALVTDIGSSVSHGAVVAR
Mvan_1818|M.vanbaalenii_PYR-1       T-IQDARDVQRGEILVAPVTDVGWTPYFTVIAALITDIGSSVSHGAVVAR
MAV_5062|M.avium_104                S-ADDLDDLEPDEILVCRTTDPSWASAFHLAAGAVIDIGSTSSHGAIIAR
TH_4230|M.thermoresistible__bu      E-LDGIGCLEKGDILITNSTDPGWTPVFAIIGGLILETGGMLAHGSCLSR
MSMEG_3934|M.smegmatis_MC2_155      I-ISTANRLGITSSLCGQAPSTRPEFAEHLVRMGITSVSVNPDAAGAARR
MLBr_00955|M.leprae_Br4923          LTLSAWSENETPELRELADIARRISPLRVHMTEDHTRLDDSSDTAVRLAI
                                                .                         .     .     

Mb2073c|M.bovis_AF2122/97           EFGFPCVVDAQGATRFLPPGALVEVDGATGEIHVVELASEDGPALPGSDL
Rv2047c|M.tuberculosis_H37Rv        EFGFPCVVDAQGATRFLPPGALVEVDGATGEIHVVELASEDGPALPGSDL
MMAR_3024|M.marinum_M               EFGFPCVVDAQGATRFLPPGALIEVDGTTGEIQVLELAAEGDSSVTQSDP
MUL_2265|M.ulcerans_Agy99           EFGFPCVVDAQGATRFLPPGALIEVDGTTGEIQVLELAAEGDSSVTQSDP
Mflv_0493|M.gilvum_PYR-GCK          EYGLPCVVNTLVGTQVLRTGDRVRVDGDRGLVTVLDSP------------
Mvan_1818|M.vanbaalenii_PYR-1       EYGLPCVVNTLVGTQVLRTGDRVRVDGDRGVVTRLG--------------
MAV_5062|M.avium_104                EMGMPCVIGTGNGTQLLRTGDFIRVDGSTGIVTVLQEAKRA---------
TH_4230|M.thermoresistible__bu      EYGLPAVTVAN-ACSHIADGAHIRVDGHTGMVSVLDDELAAAR-------
MSMEG_3934|M.smegmatis_MC2_155      AVAAAERRLLLDSVRHPRHAPTASPRNPL---------------------
MLBr_00955|M.leprae_Br4923          NTGHADVVSATPLIVMMTTLRLQDSKDSSAKS------------------
                                      . .                     .                       

Mb2073c|M.bovis_AF2122/97           SR--
Rv2047c|M.tuberculosis_H37Rv        SR--
MMAR_3024|M.marinum_M               ADLA
MUL_2265|M.ulcerans_Agy99           ADLA
Mflv_0493|M.gilvum_PYR-GCK          ----
Mvan_1818|M.vanbaalenii_PYR-1       ----
MAV_5062|M.avium_104                ----
TH_4230|M.thermoresistible__bu      ----
MSMEG_3934|M.smegmatis_MC2_155      ----
MLBr_00955|M.leprae_Br4923          ----