For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MTREVASWWRYATSAPGLARPVDQQFAQAFKMLEYAMRVHVTETFVAQGIFDALGKLAESAGRPGLHLEL STGYGQMVETELVAALHEVAQGRAEMAEFLARYGYRCAGEIEVSNPSWRERPELVKRMVDKYKAAPTRKN LAAAATARTRARQQAERELLAALPRWKRPLGRLLIKLAATFIPLREEGKSALAMAFDGARAACGIRGAEL AAAGVVDRSEDVFYLTIDEIRGTPPAEARALIARRRELRAAYEQIDVPDAWIGPPVAVSVANSGNSRVGS LSGVAAAHGVAEGPARVLASADDLDDLEPDEILVCRTTDPSWASAFHLAAGAVIDIGSTSSHGAIIAREM GMPCVIGTGNGTQLLRTGDFIRVDGSTGIVTVLQEAKRA
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. avium 104 | MAV_5062 | - | - | 100% (389) | pyruvate, water dikinase |
M. avium 104 | MAV_1955 | - | 6e-69 | 37.27% (381) | PEP-utilizing protein |
M. avium 104 | MAV_5056 | - | 9e-62 | 38.07% (394) | PEP-utilizing protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2073c | - | 3e-31 | 29.79% (339) | hypothetical protein Mb2073c |
M. gilvum PYR-GCK | Mflv_0493 | - | 3e-34 | 35.25% (295) | pyruvate, water dikinase |
M. tuberculosis H37Rv | Rv2047c | - | 3e-31 | 29.79% (339) | hypothetical protein Rv2047c |
M. leprae Br4923 | MLBr_00955 | ppdK | 2e-07 | 34.00% (100) | pyruvate phosphate dikinase |
M. abscessus ATCC 19977 | - | - | - | - | - |
M. marinum M | MMAR_3024 | - | 9e-33 | 30.45% (335) | hypothetical protein MMAR_3024 |
M. smegmatis MC2 155 | MSMEG_3934 | - | 7e-20 | 39.68% (126) | phosphoenolpyruvate synthase |
M. thermoresistible (build 8) | TH_4230 | - | 1e-26 | 27.39% (314) | PUTATIVE putative phosphoenolpyruvate synthase |
M. ulcerans Agy99 | MUL_2265 | - | 2e-33 | 30.45% (335) | hypothetical protein MUL_2265 |
M. vanbaalenii PYR-1 | Mvan_1818 | - | 2e-31 | 32.55% (298) | pyruvate, water dikinase |
CLUSTAL 2.0.9 multiple sequence alignment Mb2073c|M.bovis_AF2122/97 MRIAVTGASGVLGRGLTARLLSQGHEVVGIARHRPDSWPSSADFIAADIR Rv2047c|M.tuberculosis_H37Rv MRIAVTGASGVLGRGLTARLLSQGHEVVGIARHRPDSWPSSADFIAADIR MMAR_3024|M.marinum_M MRVAVTGAGGVLGRGLASRLLSQGHEVVGMSRRRPDSWPSQADFVAGDIR MUL_2265|M.ulcerans_Agy99 MRVAVTGAGGVLGRGLASRLLSQGHEVVGMSRRRPDSWPSQADFVAGDIR Mflv_0493|M.gilvum_PYR-GCK -------------------MFDASSRIVDLADVLDDSFGGKALGLAELTR Mvan_1818|M.vanbaalenii_PYR-1 ----------------------MAPATIEFDDVTDDRFGGKAAGLAELRR MAV_5062|M.avium_104 -------------------------------------------------- TH_4230|M.thermoresistible__bu --------------------MSYIVEFSEPAAVQRAVAGGKGAHLASLTT MSMEG_3934|M.smegmatis_MC2_155 ---------------MDIMSDRYVRTLDILTIADAEEAGGKGANLGELVA MLBr_00955|M.leprae_Br4923 -------------------------------------------------- Mb2073c|M.bovis_AF2122/97 DATAVESAMTGADVVAHCAWVRGR------NDHINIDGTANVLKAMAETG Rv2047c|M.tuberculosis_H37Rv DATAVESAMTGADVVAHCAWVRGR------NDHINIDGTANVLKAMAETG MMAR_3024|M.marinum_M DAAAVRRAITGADVVAHCAWARNPGPDGRISQQINIDGTRNVLDAMAACG MUL_2265|M.ulcerans_Agy99 DAAAVRRAITGADVVAHCAWARNPGPDGRISQQINIDGTRNVLDAMAACG Mflv_0493|M.gilvum_PYR-GCK LGLPVPPGFVIADASGTS----------------LGDAVTERFSRMRAAG Mvan_1818|M.vanbaalenii_PYR-1 IGLSVPVGFVIADASAHG----------------ALDAAVDRFCQMAAEG MAV_5062|M.avium_104 -------------------------------------------------- TH_4230|M.thermoresistible__bu AGFTVPPGFVVTVDAFDAAVTRNIG------ADVEKILAGTDFADADAVE MSMEG_3934|M.smegmatis_MC2_155 ADLPVPHGFVVMRSAYLDSVRMGG---VEAELAALHTEALTHAADTARLS MLBr_00955|M.leprae_Br4923 -------------------------------------------------- Mb2073c|M.bovis_AF2122/97 TGRIVFTSS-------------------------GHQPRVEQMLADCGLE Rv2047c|M.tuberculosis_H37Rv TGRIVFTSS-------------------------GHQPRVEQMLADCGLE MMAR_3024|M.marinum_M TGRIVFPSSPHVYRPGVPMPATEHGAVAPASAEGRHKAGVEQMLQESGAQ MUL_2265|M.ulcerans_Agy99 TGRIVFPSSPHVYRPGLPMPATEHGAVAPASAEGRHKAGVEQMLQESGAQ Mflv_0493|M.gilvum_PYR-GCK QTPVAVRSS--------------------------------AAGEDGAEH Mvan_1818|M.vanbaalenii_PYR-1 VTPVAVRSS--------------------------------AVGEDGEDQ MAV_5062|M.avium_104 -------------------------------------------------- TH_4230|M.thermoresistible__bu EAAAKVRALVTDLDVPADIASAITAAYNKLGSDAAVAVRSSGTAEDMAEA MSMEG_3934|M.smegmatis_MC2_155 ELCRRMQSLVNKAGLSPSVRDATLAAYRALGTDVVVAVRSSATGEDGRDA MLBr_00955|M.leprae_Br4923 ----------------------------------------------MPGQ Mb2073c|M.bovis_AF2122/97 WVAVRCALIFGRN-VDNWVQRLFALPVLPAGYADRVVQVVHSDDAQRLLV Rv2047c|M.tuberculosis_H37Rv WVAVRCALIFGRN-VDNWVQRLFALPVLPAGYADRVVQVVHSDDAQRLLV MMAR_3024|M.marinum_M WVAVRSALIVGRN-IDNWVRRLFALPAFPDGSADDVLQVVHLDDVLRLLT MUL_2265|M.ulcerans_Agy99 WVAVRSALIVGRN-IDNWVRRLFALPAFPDGSADDVLQVVHLDDVLRLLT Mflv_0493|M.gilvum_PYR-GCK SFAGQYDTVLG----VGSVDELTAAVEKCVRSAGSERAAAYQDGGAAARM Mvan_1818|M.vanbaalenii_PYR-1 SFAGQYDTVLG----VASVDDFTAAVRRCAGSVASQRASSYS-GHSPATM MAV_5062|M.avium_104 -------------------------------------------------- TH_4230|M.thermoresistible__bu SFAGQYDTYLDVVGTTAVLDAVKRCWASLYTTRAVAYRSGKELDTSTVKL MSMEG_3934|M.smegmatis_MC2_155 SFAGMNRTITNVMGEVALLDAVTQCWMSLFSPRVITYRASRGFTAAP-AM MLBr_00955|M.leprae_Br4923 SHKEPHRRATSTPRSLKQATSELRWALSLAAPESPAFMRHLLGNAHDKVD Mb2073c|M.bovis_AF2122/97 RALLDTVIDSGPVNLAAPGELTFRRIAAALGRPMVPIGSPVLRRVTSFAE Rv2047c|M.tuberculosis_H37Rv RALLDTVIDSGPVNLAAPGELTFRRIAAALGRPMVPIGSPVLRRVTSFAE MMAR_3024|M.marinum_M RAVSDVGAGTGPVNLAAPGLPTLREIAMALRRPILPVG-AVLRRIGSVAE MUL_2265|M.ulcerans_Agy99 RAVSDVGAGTGPVNLAAPGLPTLREIATALRRPILPVG-AALRRIGSVAE Mflv_0493|M.gilvum_PYR-GCK HLVVQQMVDARAAGVVFTADPTSGRRDLLVIDAVRGLGESLVDGSTASDH Mvan_1818|M.vanbaalenii_PYR-1 HVVVQQMVDARAAGVVFTADPATGRRDLMVIDAIAGLGEALVDGSASPDH MAV_5062|M.avium_104 -------------------------------------------------- TH_4230|M.thermoresistible__bu AVVVQEMVEAEVSGVMFTANPFTTATDELVINASWGLGEGIVSGILTPDQ MSMEG_3934|M.smegmatis_MC2_155 AVVVQQMLSADRAGVAFTSDPSTGDADHIVIEAAFGQGEVVVSGKVEPDT MLBr_00955|M.leprae_Br4923 ITTSSEHVAAFTEHAIVLLNGNAHQTRELLGGKGYNINAMRRHQLAVPPA Mb2073c|M.bovis_AF2122/97 LELLHSAPLMDVTLLRD----------------------RWGFQPAWNAE Rv2047c|M.tuberculosis_H37Rv LELLHSAPLMDVTLLRD----------------------RWGFQPAWNAE MMAR_3024|M.marinum_M FQLVQGVPVMDTARLHD----------------------EWKFQPAFTAE MUL_2265|M.ulcerans_Agy99 FQLVQGVPVMDTARLHD----------------------EWKFQPAFTAE Mflv_0493|M.gilvum_PYR-GCK FVLTHAG-----DTVTT----------------------EASSQPALADD Mvan_1818|M.vanbaalenii_PYR-1 VVLNADG-----STAVR----------------------EVGTAPVLSSD MAV_5062|M.avium_104 -------------------------------------------------- TH_4230|M.thermoresistible__bu FTLDKADLTVRDVTIGPKEVRVVRNPETGQGTVTLDNDEASRARRTLDDA MSMEG_3934|M.smegmatis_MC2_155 YVIDKRTLEVRDVRIGFKAIKIVRGDDGADSMVQLER--SQAEARVLDDD MLBr_00955|M.leprae_Br4923 FCITTEVGVRYLAAPTP-------------------------TMEAIWND Mb2073c|M.bovis_AF2122/97 ECLEDFTLAVRGRIGLGKRTFSLPWRLANIQDLPAVDSPADDGVAPRLAG Rv2047c|M.tuberculosis_H37Rv ECLEDFTLAVRGRIGLGKRTFSLPWRLANIQDLPAVDSPADDGVAPRLAG MMAR_3024|M.marinum_M ESVEDFALAVRGRVSLGRRVVSLPWRLANIQDLPAVDAPAQDGVVPRLAG MUL_2265|M.ulcerans_Agy99 ESVEDFALAVRGRVSLGRRVVSLPWRLANIQDLPAIDASAQDGVVPRLAG Mflv_0493|M.gilvum_PYR-GCK EIDRIRTGALLAAAHWG-RPLDLEWAIDRDGLLWWLQARPITTLP----- Mvan_1818|M.vanbaalenii_PYR-1 DVAEIRSGALRAARHWG-RPLDLEWAIDGTGKLWWLQARPITTLP----- MAV_5062|M.avium_104 -------------------------------------------------- TH_4230|M.thermoresistible__bu ALVRLGDIGRRIEEHFDSLPQDVEWAYAD-DTFYVLQSRAVTGVDFT--- MSMEG_3934|M.smegmatis_MC2_155 ALRKIATLAVATETHNG-CPQDIEWVIAD-GAVWLVQARPITTLG----- MLBr_00955|M.leprae_Br4923 VLDQMRWLEAETSRTFGWGPRPLLVSIRS--------------------- Mb2073c|M.bovis_AF2122/97 PEGANGEFDTPIDPRFPTYLATNLSEALPGPFSPSSASVTVRGLRAGGVG Rv2047c|M.tuberculosis_H37Rv PEGANGEFDTPIDPRFPTYLATNLSEALPGPFSPSSASVTVRGLRAGGVG MMAR_3024|M.marinum_M PEGVNGEFDTPIDPRFPTFLATNLSEALPGPFSPSSASVTVRGLRAGGVG MUL_2265|M.ulcerans_Agy99 PEGVNGEFDTPIDPRFPTFLATNLSEALPGPFSPSSASVTVRGLRAGGVG Mflv_0493|M.gilvum_PYR-GCK --GDPNEMDTPVTGPTHVYTRCNIGEMMPGAFCPLTASVSGHAIDY-AMQ Mvan_1818|M.vanbaalenii_PYR-1 --GDLNEMDSPVAGSDHVYTRCNIGEMMPGAFCPLTASVSGYAIDY-AMQ MAV_5062|M.avium_104 -------------------------------------------------- TH_4230|M.thermoresistible__bu WDDDVDAWQWSRPHADTIWTRGFADEYWTGAITPLFYSVRGAEQTSSYQR MSMEG_3934|M.smegmatis_MC2_155 ----SAGSTAGDEPSVLIRGLPAAPGVASGRVRVLLAPDDGDKLTDGEIL MLBr_00955|M.leprae_Br4923 --GAVQSMPGMMDTILNLGINDPVEQALAAASPSPIPQTFARDTRLRFIR Mb2073c|M.bovis_AF2122/97 IAERLRPSGVIQREIAMRTVAVFAHRLYGAITSAHFMAATVPFAKPATIV Rv2047c|M.tuberculosis_H37Rv IAERLRPSGVIQREIAMRTVAVFAHRLYGAITSAHFMAATVPFAKPATIV MMAR_3024|M.marinum_M IAERLRPGGVIQREIAMRTVAVFAHRLYGAITSAHFMAETVPFAKPAMIV MUL_2265|M.ulcerans_Agy99 IAERLRPGGVIQREIAMRTVAVFAHRLYGAITSAHFMAETVPFAKPAMIV Mflv_0493|M.gilvum_PYR-GCK MVQVAGGVQERYEDRARQVGYFFGHMFLNMTEGTALSSGILGNSLEQFSL Mvan_1818|M.vanbaalenii_PYR-1 MTQVVARAQPRYEKPWLQVGYFYGHMFLNLTEGTALSSGILGNSREQFSM MAV_5062|M.avium_104 ---------------MTREVASWWRYATSAPGLARPVDQQFAQAFKMLEY TH_4230|M.thermoresistible__bu SAKLWG---ADRLAALPQFKYHKAEVYFNVENQEEFLRYTCPPMFRAAAS MSMEG_3934|M.smegmatis_MC2_155 VAPTTNPDWLPTIRRAAALVTETGGMTCHAAIVARELGVPCVVGARSATV MLBr_00955|M.leprae_Br4923 TYRRIVDPLNPPPANTYDQLRAAIESIFSSWNSPRAVAYRTHYGLDDQSG Mb2073c|M.bovis_AF2122/97 SNSGFFGPSMASLPIFGAQRPPSESS-RARRWLRTLRNIGVFGVNLVGLS Rv2047c|M.tuberculosis_H37Rv SNSGFFGPSMASLPIFGAQRPPSESS-RARRWLRTLRNIGVFGVNLVGLS MMAR_3024|M.marinum_M SNSGFFGPSMGSLPIFGEERPPAESS-FVRRQLRTVRNIGVFGVNLVGLS MUL_2265|M.ulcerans_Agy99 SNSGFFGPSMGSLPIFGEERPPAESS-FVRRQLCTVRNIGVFGVNLVGLS Mflv_0493|M.gilvum_PYR-GCK SVCGRVIDELEPGPPKPFVRKLINTVRLSTFALSSAPAIRRLPQTIAAFP Mvan_1818|M.vanbaalenii_PYR-1 SICGRVVDELEAKPPRPFARKLVNTVRLTSHALSAGPAIRRLADQIAGWP MAV_5062|M.avium_104 AMRVHVTETFVAQGIFDALGKLAESAGRPGLHLELSTGYG---------- TH_4230|M.thermoresistible__bu GYLPPSRAAAVAEDPFSWAGYAKIHARILGLDITQSFHKWIASVEDYMQN MSMEG_3934|M.smegmatis_MC2_155 ALAVGSMVTVDGTRGEVTTGRLPETVRTTTTPQEPAPHITG--------- MLBr_00955|M.leprae_Br4923 TAVIVQAMVFGNQGAYSGAGTLFSRNPITRESKLFGEWLPG--------- Mb2073c|M.bovis_AF2122/97 AGSPRDTDAYVADVDRLERLAFDNLATHDDRRLLSLILLARDHVVHGWVL Rv2047c|M.tuberculosis_H37Rv AGSPRDTDAYVADVDRLERLAFDNLATHDDRRLLSLILLARDHVVHGWVL MMAR_3024|M.marinum_M AGSALDTNDFIADVDRLEQLAGGDVTTLDDRRLLSLILLARDHVVHGWVL MUL_2265|M.ulcerans_Agy99 AGSALDTNDFIADVDRLEQLAGGDVTTLDDRRLLSLILLARDHVVHGWVL Mflv_0493|M.gilvum_PYR-GCK PITSRDPAVVLRHLE-------AGVDIYREVTLIHVRSSSRSAVAANVLE Mvan_1818|M.vanbaalenii_PYR-1 IPSHEDARLVLQQLE-------SGVQLYCDVTLTHVRSSSRAAVAANILE MAV_5062|M.avium_104 -------------------------QMVETELVAALHEVAQGRAEMAEFL TH_4230|M.thermoresistible__bu RIEEADGLGDEELRKLTDRALQKYIDDRMEFVEGLLYNMWSGFQIHASLV MSMEG_3934|M.smegmatis_MC2_155 ------------------------EATGTKVYVNLAMPDSAEAVAAQDVD MLBr_00955|M.leprae_Br4923 -------------------------GQGDDVVSGLVEVQPITSLRDEQPT Mb2073c|M.bovis_AF2122/97 ASGSFMLCAAFNVLLRGLCGRDTAPAAGPELVSARSVEAVQRLVAAARRD Rv2047c|M.tuberculosis_H37Rv ASGSFMLCAAFNVLLRGLCGRDTAPAAGPELVSARSVEAVQRLVAAARRD MMAR_3024|M.marinum_M ASGSFMLCAAFNVLLRAVSGRDTAPAAGPELVSARSVEAVQRLVAAARHD MUL_2265|M.ulcerans_Agy99 ASGSFMLCAAFNVLLRAVSGRDTAPAAGPELVSARSVEAVQRLVDAARHD Mflv_0493|M.gilvum_PYR-GCK SHLVRRAAKRGASDTAGSAEAIRLMTGAG-VESALMVEELTAVVSMLRRD Mvan_1818|M.vanbaalenii_PYR-1 STLVRQAVKNGRSEEEGQAEAARLMAGASDVESAMMLDQLQSVVRAIAAD MAV_5062|M.avium_104 ARYGYRCAGEIEVSNPSWRER---------------PELVKRMVDKYKAA TH_4230|M.thermoresistible__bu LNGLGTLLAKWYDGDNQMIFVDLITGLPQRTITLQENLDLWDLAAEIRRS MSMEG_3934|M.smegmatis_MC2_155 GVGLLRAEFMLTEALAGRHPRDLITKGEQDTLVDAMAAAVTRIGTAFAPR MLBr_00955|M.leprae_Br4923 VYDELVDTAGRLERLGSDVQEIEFTTEDSKLWLLQTRVAERSAQVAVRLA Mb2073c|M.bovis_AF2122/97 PVVIR--LLAEPGERLDKLAVEAP--EFHSAVLAELTLIGHRGPAEVEMA Rv2047c|M.tuberculosis_H37Rv PVVIR--LLAEPGERLDKLAVEAP--EFHSAVLAELTLIGHRGPAEVEMA MMAR_3024|M.marinum_M EAVIR--LLSEPGDRLGKLAVAAP--HFYDAVRQELSLIGHRGPAEVEMM MUL_2265|M.ulcerans_Agy99 EAVIR--LLSEPGDRLGKLAVAAP--HFYDAVRQELSLIGHRGPAEVEMM Mflv_0493|M.gilvum_PYR-GCK GDAAARFLAAPAGEAVTRLRAAET--PSGAALRTFLDRHGHRGYRELCMR Mvan_1818|M.vanbaalenii_PYR-1 SGVATRFLAAAPDVAVVELQRADN--ASGEALRQFLLRHGHRGYRELCMR MAV_5062|M.avium_104 PTRKN--LAAAATARTRARQQAER--ELLAALPRWKRPLG---------- TH_4230|M.thermoresistible__bu PALRKLFEQSEPHEFFDKLAVHPDGAEAHRRYQQLLKDHGHRGHADRDFI MSMEG_3934|M.smegmatis_MC2_155 PVIYR--AMDFRTNEFRGLAGGEQ-----FEPVEHNPMIGYRGCYR---- MLBr_00955|M.leprae_Br4923 LQLWQEGLIDDAEALRRVTPVHVET------------------------- Mb2073c|M.bovis_AF2122/97 ATSYADNPELLVRMVAKTLRAVP--------------------------A Rv2047c|M.tuberculosis_H37Rv ATSYADNPELLVRMVAKTLRAVP--------------------------A MMAR_3024|M.marinum_M STSYADNPELLVGMVAKTLSTSS--------------------------V MUL_2265|M.ulcerans_Agy99 STSYADNPELLVGMVAKTLSTSS--------------------------V Mflv_0493|M.gilvum_PYR-GCK DPSWADDPDGLGAMMQVMLRGAAPENPA---------------------A Mvan_1818|M.vanbaalenii_PYR-1 DPSWAQDAGGLGAMMQVMVRAASSDRQP---------------------A MAV_5062|M.avium_104 -------------------------------------------------- TH_4230|M.thermoresistible__bu FPRRIEDPSIDYRSLQALLSGDGMQRPDEQERKQAAKREAATADVIARLE MSMEG_3934|M.smegmatis_MC2_155 -------------------------------------------------- MLBr_00955|M.leprae_Br4923 -------------------------------------------------- Mb2073c|M.bovis_AF2122/97 PQPPTPVIPLRAKPVALLAARQLRDREVRRDRMVRAIWVLRALLREYGRR Rv2047c|M.tuberculosis_H37Rv PQPPTPVIPLRAKPVALLAARQLRDREVRRDRMVRAIWVLRALLREYGRR MMAR_3024|M.marinum_M PQPPQPSIPLQAKPIAVLAARQLRDREARRDKMVRAIWVLRALLREHGRR MUL_2265|M.ulcerans_Agy99 PQPPQPSIPLQAKPIAVLAARQLRDREARRDKMVRAIWVLRALLREHGRR Mflv_0493|M.gilvum_PYR-GCK TAPSDPAQSRTLRVLARLAQAGARGREETKSRMALMAHLLKRGYRHLGEV Mvan_1818|M.vanbaalenii_PYR-1 HSPTEAPTSPAIRFLARLAQGGARGREETKSKMALMAHALKRGYRHLGEV MAV_5062|M.avium_104 ------------RLLIKLAATFIPLREEGKSALAMAFDGARAACGIRGAE TH_4230|M.thermoresistible__bu AKPFGRLRADLFRMLLDYAHRFMVLRDDERHYVDRATMSKKRAFLELGRR MSMEG_3934|M.smegmatis_MC2_155 -------YIKEPDLFALELSALARAREHTPNIHLMIPFVRTRWELEECLA MLBr_00955|M.leprae_Br4923 -----------VLLPVLQPENHLSATLLAKGTPTCPGVISGKAYTEVDEA Mb2073c|M.bovis_AF2122/97 LTEAGVFDTPDDVFYLLV-DEIDALP-------ADVSGLVARRRAEQRRL Rv2047c|M.tuberculosis_H37Rv LTEAGVFDTPDDVFYLLV-DEIDALP-------ADVSGLVARRRAEQRRL MMAR_3024|M.marinum_M LAEAGVLHASDDVFYLLV-DELDALP-------ADVAELVARRRAEQRRL MUL_2265|M.ulcerans_Agy99 LAEAGVLHASDDVFYLLV-DEVDALP-------ADVAELVARRRAEQRRL Mflv_0493|M.gilvum_PYR-GCK LHEAGRLPDADLVFFFDR-RELPLVVSG--DDVTELVHRARQRREALPFQ Mvan_1818|M.vanbaalenii_PYR-1 LARSGRLPDADLVFFFDR-SELPRVVGD--DDISELVQSAVKRREALAYQ MAV_5062|M.avium_104 LAAAGVVDRSEDVFYLTI-DEIRGTPP------AEARALIARRRELRAAY TH_4230|M.thermoresistible__bu LLARDLIERLDDVYFLTK-DELYELMAERAPQALVRAKIAGRRKQFEAFD MSMEG_3934|M.smegmatis_MC2_155 LVDASPLRRHRNLHRWVM-AEVPSVVH------------------WLPEY MLBr_00955|M.leprae_Br4923 LDAAESAEQVILVRDHTRPDDVLGMLAS---------------QGVVTEV * : :: Mb2073c|M.bovis_AF2122/97 AGIVPPTVFSGS---WEPSPSSAAALAAGDTLRGVGVCGGRVRGRVRIVR Rv2047c|M.tuberculosis_H37Rv AGIVPPTVFSGS---WEPSPSSAAALAAGDTLRGVGVCGGRVRGRVRIVR MMAR_3024|M.marinum_M TAVVPPTVFSGK---WEPSTASAAALTAGGTLRGVGVCGGRVRGRVRIVR MUL_2265|M.ulcerans_Agy99 TAVVPPTVFSGK---WEPSTASAAALTAEGTLRGVGVCGGRVRGRVRIVR Mflv_0493|M.gilvum_PYR-GCK AALEFGDVSVGR---PTPIVR--AAVSGDGVVAGRPAGHGSVEGVVRVAR Mvan_1818|M.vanbaalenii_PYR-1 DSLEFEDVSVGR---PRPVVAPPVITSTADQVVGRPASRGTVEGTVRVAK MAV_5062|M.avium_104 EQIDVPDAWIGP---PVAVSVANSGNSRVGSLSGVAAAHGVAEGPARVLA TH_4230|M.thermoresistible__bu RKDAIPPMYLQHGREWIDPTEISGGDVDPRALQGLPTSPGTVEGRARVVR MSMEG_3934|M.smegmatis_MC2_155 VGMGIDGVSIGS----NDLTQLMLGVDRDSETCAELFDESDAAVLDAISR MLBr_00955|M.leprae_Br4923 GGAASHAAVVSR--ELSRVAVVGCGQGTAVSLAGKQITVDGDKGEVRQGN . . Mb2073c|M.bovis_AF2122/97 --PETIDDLQPGEILVAEVTDVGYTAAFCYAAAVVTELGGPMSHAAVVAR Rv2047c|M.tuberculosis_H37Rv --PETIDDLQPGEILVAEVTDVGYTAAFCYAAAVVTELGGPMSHAAVVAR MMAR_3024|M.marinum_M --PETIDELEPGEILVAEVTDVGYTAAFCYAAAVVTELGGPMSHAAVVAR MUL_2265|M.ulcerans_Agy99 --PETIDELEPGEILVAEVTDVGYTAAFCYAAAVVTELGGPMSHAAVVAR Mflv_0493|M.gilvum_PYR-GCK S-VVEARDLQPGEILVAPVTDVGWTPYFAVIAALVTDIGSSVSHGAVVAR Mvan_1818|M.vanbaalenii_PYR-1 T-IQDARDVQRGEILVAPVTDVGWTPYFTVIAALITDIGSSVSHGAVVAR MAV_5062|M.avium_104 S-ADDLDDLEPDEILVCRTTDPSWASAFHLAAGAVIDIGSTSSHGAIIAR TH_4230|M.thermoresistible__bu E-LDGIGCLEKGDILITNSTDPGWTPVFAIIGGLILETGGMLAHGSCLSR MSMEG_3934|M.smegmatis_MC2_155 I-ISTANRLGITSSLCGQAPSTRPEFAEHLVRMGITSVSVNPDAAGAARR MLBr_00955|M.leprae_Br4923 LTLSAWSENETPELRELADIARRISPLRVHMTEDHTRLDDSSDTAVRLAI . . . Mb2073c|M.bovis_AF2122/97 EFGFPCVVDAQGATRFLPPGALVEVDGATGEIHVVELASEDGPALPGSDL Rv2047c|M.tuberculosis_H37Rv EFGFPCVVDAQGATRFLPPGALVEVDGATGEIHVVELASEDGPALPGSDL MMAR_3024|M.marinum_M EFGFPCVVDAQGATRFLPPGALIEVDGTTGEIQVLELAAEGDSSVTQSDP MUL_2265|M.ulcerans_Agy99 EFGFPCVVDAQGATRFLPPGALIEVDGTTGEIQVLELAAEGDSSVTQSDP Mflv_0493|M.gilvum_PYR-GCK EYGLPCVVNTLVGTQVLRTGDRVRVDGDRGLVTVLDSP------------ Mvan_1818|M.vanbaalenii_PYR-1 EYGLPCVVNTLVGTQVLRTGDRVRVDGDRGVVTRLG-------------- MAV_5062|M.avium_104 EMGMPCVIGTGNGTQLLRTGDFIRVDGSTGIVTVLQEAKRA--------- TH_4230|M.thermoresistible__bu EYGLPAVTVAN-ACSHIADGAHIRVDGHTGMVSVLDDELAAAR------- MSMEG_3934|M.smegmatis_MC2_155 AVAAAERRLLLDSVRHPRHAPTASPRNPL--------------------- MLBr_00955|M.leprae_Br4923 NTGHADVVSATPLIVMMTTLRLQDSKDSSAKS------------------ . . . Mb2073c|M.bovis_AF2122/97 SR-- Rv2047c|M.tuberculosis_H37Rv SR-- MMAR_3024|M.marinum_M ADLA MUL_2265|M.ulcerans_Agy99 ADLA Mflv_0493|M.gilvum_PYR-GCK ---- Mvan_1818|M.vanbaalenii_PYR-1 ---- MAV_5062|M.avium_104 ---- TH_4230|M.thermoresistible__bu ---- MSMEG_3934|M.smegmatis_MC2_155 ---- MLBr_00955|M.leprae_Br4923 ----