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MIGPIAELTDPIRGESAPDRLWTLTNVGEATPDILSPLCWSLWGTGVEFASRGGLYDFGVLPASALVVPN DPNQWSTACFFGRQAMNVDRARELAGLLPGMTGDDFERDLLGSVRPDATPTKSDPKRLPVAAVKTPWVLL RSRSAARDAHSAQMSWWRATVLGGDSKDPKALLADSVQRFSSVMRVHVRSRMILNALRSQVESIVGKLGC SDLVPVLLAGYGGVIETELADDVWSLGQGRLSMDEFLLRHGFHGPNEGNVIGHSWREDHDAVKRAAQAHA GRAEEERPSVRVQRAVAARQRAEAELLATLSLPRRLMLRKLLSFTGAHVRAVELGKAGFLTAIDGCRAAA AALGRDLVRAGILERPDDTCYLTVEELLAPLPSNVRELVDFRRARREEYRRIEVPTVFTGMPVPIDPGGA SAGQDAAVRGMPAGTGVFEGTVRVVLDAESDDTLDDGEVLVCKMVDPGWTALVSLAGALVTDIGSPASHG AIVARELGIACVVGTGNGTRVLHTGDVVRVDGVTGEIAVLQRAES
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. avium 104 | MAV_1955 | - | - | 100% (535) | PEP-utilizing protein |
M. avium 104 | MAV_5056 | - | 5e-81 | 32.77% (537) | PEP-utilizing protein |
M. avium 104 | MAV_5062 | - | 9e-69 | 37.27% (381) | pyruvate, water dikinase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2073c | - | 7e-33 | 36.10% (277) | hypothetical protein Mb2073c |
M. gilvum PYR-GCK | Mflv_0493 | - | 4e-37 | 29.30% (570) | pyruvate, water dikinase |
M. tuberculosis H37Rv | Rv2047c | - | 7e-33 | 36.10% (277) | hypothetical protein Rv2047c |
M. leprae Br4923 | MLBr_00955 | ppdK | 4e-09 | 35.64% (101) | pyruvate phosphate dikinase |
M. abscessus ATCC 19977 | - | - | - | - | - |
M. marinum M | MMAR_3024 | - | 3e-34 | 36.63% (273) | hypothetical protein MMAR_3024 |
M. smegmatis MC2 155 | MSMEG_3934 | - | 5e-22 | 46.85% (111) | phosphoenolpyruvate synthase |
M. thermoresistible (build 8) | TH_4555 | - | 2e-25 | 30.79% (302) | PUTATIVE putative phosphoenolpyruvate synthase |
M. ulcerans Agy99 | MUL_2265 | - | 2e-34 | 36.26% (273) | hypothetical protein MUL_2265 |
M. vanbaalenii PYR-1 | Mvan_1818 | - | 1e-34 | 27.02% (581) | pyruvate, water dikinase |
CLUSTAL 2.0.9 multiple sequence alignment Mb2073c|M.bovis_AF2122/97 MRIAVTGASGVLGRGLTARLLSQGHEVVGIARHRPDSWPSSADFIAADIR Rv2047c|M.tuberculosis_H37Rv MRIAVTGASGVLGRGLTARLLSQGHEVVGIARHRPDSWPSSADFIAADIR MMAR_3024|M.marinum_M MRVAVTGAGGVLGRGLASRLLSQGHEVVGMSRRRPDSWPSQADFVAGDIR MUL_2265|M.ulcerans_Agy99 MRVAVTGAGGVLGRGLASRLLSQGHEVVGMSRRRPDSWPSQADFVAGDIR Mflv_0493|M.gilvum_PYR-GCK -------------------MFDASSRIVDLADVLDDSFGGKALGLAELTR Mvan_1818|M.vanbaalenii_PYR-1 ----------------------MAPATIEFDDVTDDRFGGKAAGLAELRR MAV_1955|M.avium_104 -------------------------------------------------- TH_4555|M.thermoresistible__bu -MMTDMSAVTSPNTVEAEHTVSNVIRFADPGATDPRLVGGKGMNLGELVA MSMEG_3934|M.smegmatis_MC2_155 ---------------MDIMSDRYVRTLDILTIADAEEAGGKGANLGELVA MLBr_00955|M.leprae_Br4923 -------------------------------------------------- Mb2073c|M.bovis_AF2122/97 DATAVESAMTGADVVAHCAWVRG--R------NDHINIDGTANVLKAMAE Rv2047c|M.tuberculosis_H37Rv DATAVESAMTGADVVAHCAWVRG--R------NDHINIDGTANVLKAMAE MMAR_3024|M.marinum_M DAAAVRRAITGADVVAHCAWARN--PGPDGRISQQINIDGTRNVLDAMAA MUL_2265|M.ulcerans_Agy99 DAAAVRRAITGADVVAHCAWARN--PGPDGRISQQINIDGTRNVLDAMAA Mflv_0493|M.gilvum_PYR-GCK LGLPVPPGFVIADASGTS------------------LGDAVTERFSRMRA Mvan_1818|M.vanbaalenii_PYR-1 IGLSVPVGFVIADASAHG------------------ALDAAVDRFCQMAA MAV_1955|M.avium_104 -------------------------------------------------- TH_4555|M.thermoresistible__bu AGFRVPNGFTVSTEAYAATLADS--GAADRIFELLKGLDVADLARLESTA MSMEG_3934|M.smegmatis_MC2_155 ADLPVPHGFVVMRSAYLDSVRMGGVEAELAALHTEALTHAADTARLSELC MLBr_00955|M.leprae_Br4923 -------------------------------------------------- Mb2073c|M.bovis_AF2122/97 TGTGRIVFTSS-------------------------GHQPRVEQMLADCG Rv2047c|M.tuberculosis_H37Rv TGTGRIVFTSS-------------------------GHQPRVEQMLADCG MMAR_3024|M.marinum_M CGTGRIVFPSSPHVYRPGVPMPATEHGAVAPASAEGRHKAGVEQMLQESG MUL_2265|M.ulcerans_Agy99 CGTGRIVFPSSPHVYRPGLPMPATEHGAVAPASAEGRHKAGVEQMLQESG Mflv_0493|M.gilvum_PYR-GCK AGQTPVAVRSS--------------------------------AAGEDGA Mvan_1818|M.vanbaalenii_PYR-1 EGVTPVAVRSS--------------------------------AVGEDGE MAV_1955|M.avium_104 -------------------------------------------------- TH_4555|M.thermoresistible__bu AAIRDVVTAVELPDKLAHDIERAYTELG-----ADVYVAVRSSGTAEDTA MSMEG_3934|M.smegmatis_MC2_155 RRMQSLVNKAGLSPSVRDATLAAYRALG-----TDVVVAVRSSATGEDGR MLBr_00955|M.leprae_Br4923 -------------------------------------------------- Mb2073c|M.bovis_AF2122/97 LEWVAVRCALIFGRNVDNWVQRLFALPVLPAGYADRVV-QVVHSDDAQRL Rv2047c|M.tuberculosis_H37Rv LEWVAVRCALIFGRNVDNWVQRLFALPVLPAGYADRVV-QVVHSDDAQRL MMAR_3024|M.marinum_M AQWVAVRSALIVGRNIDNWVRRLFALPAFPDGSADDVL-QVVHLDDVLRL MUL_2265|M.ulcerans_Agy99 AQWVAVRSALIVGRNIDNWVRRLFALPAFPDGSADDVL-QVVHLDDVLRL Mflv_0493|M.gilvum_PYR-GCK EHSFAGQYDTVLG---VGSVDELTAAVEKCVRSAGSER-AAAYQDGGAAA Mvan_1818|M.vanbaalenii_PYR-1 DQSFAGQYDTVLG---VASVDDFTAAVRRCAGSVASQR-ASSYS-GHSPA MAV_1955|M.avium_104 -------------------------------------------------- TH_4555|M.thermoresistible__bu EASFAGMHDTYLDIRGTGEVLDAVRRCWASMWTARAVAYREEHGFDHREA MSMEG_3934|M.smegmatis_MC2_155 DASFAGMNRTITNVMGEVALLDAVTQCWMSLFSPRVITYRASRGFTAAP- MLBr_00955|M.leprae_Br4923 ----------MPGQSHKEPHRRATSTPRSLKQATSELRWALSLAAPESPA Mb2073c|M.bovis_AF2122/97 LVRALLDTVIDSGPVNLAAPGELTFRRIAAALGRPMVPIGSPVLRRVTSF Rv2047c|M.tuberculosis_H37Rv LVRALLDTVIDSGPVNLAAPGELTFRRIAAALGRPMVPIGSPVLRRVTSF MMAR_3024|M.marinum_M LTRAVSDVGAGTGPVNLAAPGLPTLREIAMALRRPILPVG-AVLRRIGSV MUL_2265|M.ulcerans_Agy99 LTRAVSDVGAGTGPVNLAAPGLPTLREIATALRRPILPVG-AALRRIGSV Mflv_0493|M.gilvum_PYR-GCK RMHLVVQQMVDARAAGVVFTADPTSGRRDLLVIDAVRGLGESLVDGSTAS Mvan_1818|M.vanbaalenii_PYR-1 TMHVVVQQMVDARAAGVVFTADPATGRRDLMVIDAIAGLGEALVDGSASP MAV_1955|M.avium_104 -------------------------------------------------- TH_4555|M.thermoresistible__bu KIAVVVQTMAEADVSGVMYTANPLNNRTDEIVINSAYGLGESIVSGAINP MSMEG_3934|M.smegmatis_MC2_155 AMAVVVQQMLSADRAGVAFTSDPSTGDADHIVIEAAFGQGEVVVSGKVEP MLBr_00955|M.leprae_Br4923 FMRHLLGNAHDKVDITTSSEHVAAFTEHAIVLLNGNAHQTRELLGGKGYN Mb2073c|M.bovis_AF2122/97 AELELLHSAPLMDVTLLRD----------------------RWGFQPAWN Rv2047c|M.tuberculosis_H37Rv AELELLHSAPLMDVTLLRD----------------------RWGFQPAWN MMAR_3024|M.marinum_M AEFQLVQGVPVMDTARLHD----------------------EWKFQPAFT MUL_2265|M.ulcerans_Agy99 AEFQLVQGVPVMDTARLHD----------------------EWKFQPAFT Mflv_0493|M.gilvum_PYR-GCK DHFVLTHAG-----DTVTT----------------------EASSQPALA Mvan_1818|M.vanbaalenii_PYR-1 DHVVLNADG-----STAVR----------------------EVGTAPVLS MAV_1955|M.avium_104 -------------------------------------------------- TH_4555|M.thermoresistible__bu DEFTVDLGTLKIKQANVGNKKEKIVRAPDKPSGTVTLAVSEEDAGRLSLT MSMEG_3934|M.smegmatis_MC2_155 DTYVIDKRT----------------------------------------- MLBr_00955|M.leprae_Br4923 -------------------------------------------------- Mb2073c|M.bovis_AF2122/97 AEECLEDFTLAVRGRIGLGKRTFSLPWRLANIQDLPAVDSPADDGVAPRL Rv2047c|M.tuberculosis_H37Rv AEECLEDFTLAVRGRIGLGKRTFSLPWRLANIQDLPAVDSPADDGVAPRL MMAR_3024|M.marinum_M AEESVEDFALAVRGRVSLGRRVVSLPWRLANIQDLPAVDAPAQDGVVPRL MUL_2265|M.ulcerans_Agy99 AEESVEDFALAVRGRVSLGRRVVSLPWRLANIQDLPAIDASAQDGVVPRL Mflv_0493|M.gilvum_PYR-GCK DDEIDRIRTGALLAAAHWG-RPLDLEWAIDRDGLLWWLQARPITTLP--- Mvan_1818|M.vanbaalenii_PYR-1 SDDVAEIRSGALRAARHWG-RPLDLEWAIDGTGKLWWLQARPITTLP--- MAV_1955|M.avium_104 -------------------------------------------------- TH_4555|M.thermoresistible__bu DEQVAELAALGRQVMDHYGGLPQDIEWACVDG-EFFLLQTRPITGAK--- MSMEG_3934|M.smegmatis_MC2_155 ----------LEVRDVRIGFKAIKIVRGDDGADSMVQLER---------- MLBr_00955|M.leprae_Br4923 ------------INAMRRHQLAVPPAFCITTEVGVRYLAAP--------- Mb2073c|M.bovis_AF2122/97 AGPEGANGEFDTPIDP---RFPTYLATNLSEALPGPFSPSSASVTVRGLR Rv2047c|M.tuberculosis_H37Rv AGPEGANGEFDTPIDP---RFPTYLATNLSEALPGPFSPSSASVTVRGLR MMAR_3024|M.marinum_M AGPEGVNGEFDTPIDP---RFPTFLATNLSEALPGPFSPSSASVTVRGLR MUL_2265|M.ulcerans_Agy99 AGPEGVNGEFDTPIDP---RFPTFLATNLSEALPGPFSPSSASVTVRGLR Mflv_0493|M.gilvum_PYR-GCK ----GDPNEMDTPVTG---PTHVYTRCNIGEMMPGAFCPLTASVSGHAID Mvan_1818|M.vanbaalenii_PYR-1 ----GDLNEMDSPVAG---SDHVYTRCNIGEMMPGAFCPLTASVSGYAID MAV_1955|M.avium_104 --MIGPIAELTDPIRGESAPDRLWTLTNVGEATPDILSPLCWSLWGTGVE TH_4555|M.thermoresistible__bu ---FTWPEGFNDWQNGPEDPDTLWTFKYAEQYWTGGITPLFFSVRARETQ MSMEG_3934|M.smegmatis_MC2_155 -------SQAEARVLDDDALRKIATLAVATETHNGCPQDIEWVIADGAVW MLBr_00955|M.leprae_Br4923 -------TPTMEAIWNDVLDQMRWLEAETSRTFGWGPRPLLVSIRSGAVQ . : Mb2073c|M.bovis_AF2122/97 AGGVGIAERLRPS-----GVIQREIAMRTVAVFAHRLYGAITSAHFMAAT Rv2047c|M.tuberculosis_H37Rv AGGVGIAERLRPS-----GVIQREIAMRTVAVFAHRLYGAITSAHFMAAT MMAR_3024|M.marinum_M AGGVGIAERLRPG-----GVIQREIAMRTVAVFAHRLYGAITSAHFMAET MUL_2265|M.ulcerans_Agy99 AGGVGIAERLRPG-----GVIQREIAMRTVAVFAHRLYGAITSAHFMAET Mflv_0493|M.gilvum_PYR-GCK Y-AMQMVQVAGGV-----QERYEDRARQVGYFFGHMFLNMTEGTALSSGI Mvan_1818|M.vanbaalenii_PYR-1 Y-AMQMTQVVARA-----QPRYEKPWLQVGYFYGHMFLNLTEGTALSSGI MAV_1955|M.avium_104 FASRGGLYDFGVLPASALVVPNDPNQWSTACFFGRQAMNVDRARELAGLL TH_4555|M.thermoresistible__bu VGYDRMNARAGFQ------DLLGQRLYKDKYGTVYWNVDMDE-KRLRYVL MSMEG_3934|M.smegmatis_MC2_155 LVQARPITTLGSAG----STAGDEPSVLIRGLPAAPGVASGRVRVLLAPD MLBr_00955|M.leprae_Br4923 SMPGMMDTILNLG----------------INDPVEQALAAASPSPIPQTF : Mb2073c|M.bovis_AF2122/97 VPFAKPATIVSNSGFFGPSMASLPIFGAQRPPSESS-RARRWLRTLRNIG Rv2047c|M.tuberculosis_H37Rv VPFAKPATIVSNSGFFGPSMASLPIFGAQRPPSESS-RARRWLRTLRNIG MMAR_3024|M.marinum_M VPFAKPAMIVSNSGFFGPSMGSLPIFGEERPPAESS-FVRRQLRTVRNIG MUL_2265|M.ulcerans_Agy99 VPFAKPAMIVSNSGFFGPSMGSLPIFGEERPPAESS-FVRRQLCTVRNIG Mflv_0493|M.gilvum_PYR-GCK LGNSLEQFSLSVCGRVIDELEPGPPKPFVRKLINTVRLSTFALSSAPAIR Mvan_1818|M.vanbaalenii_PYR-1 LGNSREQFSMSICGRVVDELEAKPPRPFARKLVNTVRLTSHALSAGPAIR MAV_1955|M.avium_104 PGMTGDDFERDLLGSVRPDATPTKSDP-KRLPVAAVKTPWVLLRSRSAAR TH_4555|M.thermoresistible__bu PRFARPAGANVVPADMQEQMFAEPLDVVRWLKAMISFSVSPIYSLSRWKK MSMEG_3934|M.smegmatis_MC2_155 DGDKLTDGEILVAPTTNPDWLP----TIRRAAALVTETGGMTCHAAIVAR MLBr_00955|M.leprae_Br4923 ARDTRLRFIRTYR-RIVDPLNPPPANTYDQLRAAIESIFSSWNSPRAVAY . Mb2073c|M.bovis_AF2122/97 VFGVNLVGLSAGSPRDTDAYVADVDRLERLAFDNLATHDDRRLLSLILLA Rv2047c|M.tuberculosis_H37Rv VFGVNLVGLSAGSPRDTDAYVADVDRLERLAFDNLATHDDRRLLSLILLA MMAR_3024|M.marinum_M VFGVNLVGLSAGSALDTNDFIADVDRLEQLAGGDVTTLDDRRLLSLILLA MUL_2265|M.ulcerans_Agy99 VFGVNLVGLSAGSALDTNDFIADVDRLEQLAGGDVTTLDDRRLLSLILLA Mflv_0493|M.gilvum_PYR-GCK RLPQTIAAFPPITSRDPAVVLRHLE-------AGVDIYREVTLIHVRSSS Mvan_1818|M.vanbaalenii_PYR-1 RLADQIAGWPIPSHEDARLVLQQLE-------SGVQLYCDVTLTHVRSSS MAV_1955|M.avium_104 DAHSAQMSWWRATVLGGDS-------------KDPKALLADSVQRFSSVM TH_4555|M.thermoresistible__bu VIREDYLFNEAAVAKANGLSDAELRALSDDELYRYQRDLQEYAIDFMDPL MSMEG_3934|M.smegmatis_MC2_155 ELGVPCVVGARSAT---------------------VALAVGSMVTVDGTR MLBr_00955|M.leprae_Br4923 RTHYGLD--------------------------DQSGTAVIVQAMVFGNQ . Mb2073c|M.bovis_AF2122/97 RDHVVHGWVLASGSFMLCAAFNVLLRGLCGRDTAPAAGPELVSARSVEAV Rv2047c|M.tuberculosis_H37Rv RDHVVHGWVLASGSFMLCAAFNVLLRGLCGRDTAPAAGPELVSARSVEAV MMAR_3024|M.marinum_M RDHVVHGWVLASGSFMLCAAFNVLLRAVSGRDTAPAAGPELVSARSVEAV MUL_2265|M.ulcerans_Agy99 RDHVVHGWVLASGSFMLCAAFNVLLRAVSGRDTAPAAGPELVSARSVEAV Mflv_0493|M.gilvum_PYR-GCK RSAVAANVLESHLVRRAAKRGASDTAGSAEAIRLMTGAG-VESALMVEEL Mvan_1818|M.vanbaalenii_PYR-1 RAAVAANILESTLVRQAVKNGRSEEEGQAEAARLMAGASDVESAMMLDQL MAV_1955|M.avium_104 RVHVRSRMILNALRSQVESIVGKLGCSDLVPVLLAGYGGVIETELADDVW TH_4555|M.thermoresistible__bu WFGAYTAMSMFFSLHAALLAKYYTGTNELLGQDLISGLPTTLQALENRAF MSMEG_3934|M.smegmatis_MC2_155 GEVTTGRLPETVRTTTTPQEPAPHITGEATGTKVYVNLAMPDSAEAVAAQ MLBr_00955|M.leprae_Br4923 GAYSGAGTLFSRNPITRESKLFGEWLPGGQGDDVVSGLVEVQPITSLRDE Mb2073c|M.bovis_AF2122/97 QRLVAAARRDPVVIR--LLAEPGERLDKLAVEAP--EFHSAVLAELTLIG Rv2047c|M.tuberculosis_H37Rv QRLVAAARRDPVVIR--LLAEPGERLDKLAVEAP--EFHSAVLAELTLIG MMAR_3024|M.marinum_M QRLVAAARHDEAVIR--LLSEPGDRLGKLAVAAP--HFYDAVRQELSLIG MUL_2265|M.ulcerans_Agy99 QRLVDAARHDEAVIR--LLSEPGDRLGKLAVAAP--HFYDAVRQELSLIG Mflv_0493|M.gilvum_PYR-GCK TAVVSMLRRDGDAAARFLAAPAGEAVTRLRAAET--PSGAALRTFLDRHG Mvan_1818|M.vanbaalenii_PYR-1 QSVVRAIAADSGVATRFLAAAPDVAVVELQRADN--ASGEALRQFLLRHG MAV_1955|M.avium_104 SLGQGRLSMDEFLLRHGFHGPNEGNVIGHSWRED--HDAVKR----AAQA TH_4555|M.thermoresistible__bu FELTSMIRHSKVLSDAFEKHQGAAFFAELENSDEGREFLEKYREFLAEHG MSMEG_3934|M.smegmatis_MC2_155 DVDGVGLLRAEFMLTEALAGRHPRDLITKGEQDT---LVDAMAAAVTRIG MLBr_00955|M.leprae_Br4923 QP----TVYDELVDTAGRLERLGSDVQEIEFTTE----DSKLWLLQTRVA . . Mb2073c|M.bovis_AF2122/97 HRGPAEVEMAATSYADNPELLVRMVAKTLRAVP----------------- Rv2047c|M.tuberculosis_H37Rv HRGPAEVEMAATSYADNPELLVRMVAKTLRAVP----------------- MMAR_3024|M.marinum_M HRGPAEVEMMSTSYADNPELLVGMVAKTLSTSS----------------- MUL_2265|M.ulcerans_Agy99 HRGPAEVEMMSTSYADNPELLVGMVAKTLSTSS----------------- Mflv_0493|M.gilvum_PYR-GCK HRGYRELCMRDPSWADDPDGLGAMMQVMLRGAAPE--------------- Mvan_1818|M.vanbaalenii_PYR-1 HRGYRELCMRDPSWAQDAGGLGAMMQVMVRAASSD--------------- MAV_1955|M.avium_104 HAGRAEEERPSVRVQRAVAARQRAEAELLATLS----------------- TH_4555|M.thermoresistible__bu HRGHPDRDLIFKRRADDPAVDYEAFKVQLQAPEATPPIELEERVRARREA MSMEG_3934|M.smegmatis_MC2_155 TAFAPRPVIYRAMDFRTNEFRGLAGGEQFEPVEHN--------------- MLBr_00955|M.leprae_Br4923 ERSAQVAVRLALQLWQEGLIDDAEALRRVTPVH----------------- . Mb2073c|M.bovis_AF2122/97 ---------APQPPTPVIPLRAKPVALLAARQLRDREVRRDRMVRAIWVL Rv2047c|M.tuberculosis_H37Rv ---------APQPPTPVIPLRAKPVALLAARQLRDREVRRDRMVRAIWVL MMAR_3024|M.marinum_M ---------VPQPPQPSIPLQAKPIAVLAARQLRDREARRDKMVRAIWVL MUL_2265|M.ulcerans_Agy99 ---------VPQPPQPSIPLQAKPIAVLAARQLRDREARRDKMVRAIWVL Mflv_0493|M.gilvum_PYR-GCK ------NPAATAPSDPAQSRTLRVLARLAQAGARGREETKSRMALMAHLL Mvan_1818|M.vanbaalenii_PYR-1 ------RQPAHSPTEAPTSPAIRFLARLAQGGARGREETKSKMALMAHAL MAV_1955|M.avium_104 ---------------LPRRLMLRKLLSFTGAHVRAVELGKAGFLTAIDGC TH_4555|M.thermoresistible__bu AEAEVIENLGRGFLGPVKQQLFKLLQHQIIDFLVLRDDWRHFIDRITYAK MSMEG_3934|M.smegmatis_MC2_155 -------PMIGYRGCYRYIKEPDLFALELSALARAREHTPNIHLMIPFVR MLBr_00955|M.leprae_Br4923 ---------VETVLLPVLQPENHLSATLLAKGTPTCPGVISGKAYTEVDE Mb2073c|M.bovis_AF2122/97 RALLREYGRRLTEAGVFDTPDDVFYLLVDEIDALP-----ADVSGLVARR Rv2047c|M.tuberculosis_H37Rv RALLREYGRRLTEAGVFDTPDDVFYLLVDEIDALP-----ADVSGLVARR MMAR_3024|M.marinum_M RALLREHGRRLAEAGVLHASDDVFYLLVDELDALP-----ADVAELVARR MUL_2265|M.ulcerans_Agy99 RALLREHGRRLAEAGVLHASDDVFYLLVDEVDALP-----ADVAELVARR Mflv_0493|M.gilvum_PYR-GCK KRGYRHLGEVLHEAGRLPDADLVFFFDRRELPLVVSGDDVTELVHRARQR Mvan_1818|M.vanbaalenii_PYR-1 KRGYRHLGEVLARSGRLPDADLVFFFDRSELPRVVGDDDISELVQSAVKR MAV_1955|M.avium_104 RAAAAALGRDLVRAGILERPDDTCYLTVEELLAPLP----SNVRELVDFR TH_4555|M.thermoresistible__bu RKAFLEVARRCVERGRLEKEDDAFFLGETELFEVLNGTAKQPLVQAKIAA MSMEG_3934|M.smegmatis_MC2_155 TRWELEECLALVDASPLRRHRNLHRWVMAEVPSVVH-------------- MLBr_00955|M.leprae_Br4923 ALDAAESAEQVILVRDHTRPDDVLGMLASQGVVTEVG------------- : Mb2073c|M.bovis_AF2122/97 RA---EQRRLAGIVPPTVFSGSWEPSPSSAAALAAGDTLRGVGVCGGRVR Rv2047c|M.tuberculosis_H37Rv RA---EQRRLAGIVPPTVFSGSWEPSPSSAAALAAGDTLRGVGVCGGRVR MMAR_3024|M.marinum_M RA---EQRRLTAVVPPTVFSGKWEPSTASAAALTAGGTLRGVGVCGGRVR MUL_2265|M.ulcerans_Agy99 RA---EQRRLTAVVPPTVFSGKWEPSTASAAALTAEGTLRGVGVCGGRVR Mflv_0493|M.gilvum_PYR-GCK RE---ALPFQAALEFGDVSVGRPTPIVR--AAVSGDGVVAGRPAGHGSVE Mvan_1818|M.vanbaalenii_PYR-1 RE---ALAYQDSLEFEDVSVGRPRPVVAPPVITSTADQVVGRPASRGTVE MAV_1955|M.avium_104 RA---RREEYRRIEVPTVFTGMPVPIDPGGASAGQDAAVRGMPAGTGVFE TH_4555|M.thermoresistible__bu RRPDFELFESRTFTPPMFMRGETPVDEAAPAAVAGSGAINGVGTSAGQVE MSMEG_3934|M.smegmatis_MC2_155 -----WLPEYVGMGIDGVSIGSND-LTQLMLGVDRDSETCAELFDESDAA MLBr_00955|M.leprae_Br4923 ----------GAASHAAVVSRELSRVAVVGCGQGTAVSLAGKQITVDGDK . . . Mb2073c|M.bovis_AF2122/97 GRVRIVR-PETIDDLQPGEILVAEVTDVG-YTAAFCYAAAVVTELGGPMS Rv2047c|M.tuberculosis_H37Rv GRVRIVR-PETIDDLQPGEILVAEVTDVG-YTAAFCYAAAVVTELGGPMS MMAR_3024|M.marinum_M GRVRIVR-PETIDELEPGEILVAEVTDVG-YTAAFCYAAAVVTELGGPMS MUL_2265|M.ulcerans_Agy99 GRVRIVR-PETIDELEPGEILVAEVTDVG-YTAAFCYAAAVVTELGGPMS Mflv_0493|M.gilvum_PYR-GCK GVVRVARSVVEARDLQPGEILVAPVTDVG-WTPYFAVIAALVTDIGSSVS Mvan_1818|M.vanbaalenii_PYR-1 GTVRVAKTIQDARDVQRGEILVAPVTDVG-WTPYFTVIAALITDIGSSVS MAV_1955|M.avium_104 GTVRVVLDAESDDTLDDGEVLVCKMVDPG-WTALVSLAGALVTDIGSPAS TH_4555|M.thermoresistible__bu GRARVLASMTEIGTLEQGDVLVCNATDPG-WSPVFGVISGLIIETGGMLA MSMEG_3934|M.smegmatis_MC2_155 VLDAISRIISTANRLGITSSLCGQAPSTR-PEFAEHLVRMGITSVSVNPD MLBr_00955|M.leprae_Br4923 GEVRQGNLTLSAWSENETPELRELADIARRISPLRVHMTEDHTRLDDSSD * . Mb2073c|M.bovis_AF2122/97 HAAVVAREFGFPCVVDAQGATRFLPPGALVEVDGATGEIHVVELASEDGP Rv2047c|M.tuberculosis_H37Rv HAAVVAREFGFPCVVDAQGATRFLPPGALVEVDGATGEIHVVELASEDGP MMAR_3024|M.marinum_M HAAVVAREFGFPCVVDAQGATRFLPPGALIEVDGTTGEIQVLELAAEGDS MUL_2265|M.ulcerans_Agy99 HAAVVAREFGFPCVVDAQGATRFLPPGALIEVDGTTGEIQVLELAAEGDS Mflv_0493|M.gilvum_PYR-GCK HGAVVAREYGLPCVVNTLVGTQVLRTGDRVRVDGDRGLVTVLDSP----- Mvan_1818|M.vanbaalenii_PYR-1 HGAVVAREYGLPCVVNTLVGTQVLRTGDRVRVDGDRGVVTRLG------- MAV_1955|M.avium_104 HGAIVARELGIACVVGTGNGTRVLHTGDVVRVDGVTGEIAVLQRAES--- TH_4555|M.thermoresistible__bu HGACLSREHGIPAVQIVG-ATQIIPDGAYVRINGTTGLVEVLEPAPAGAA MSMEG_3934|M.smegmatis_MC2_155 AAGAARRAVAAAERRLLLDSVRHPRHAPTASPRNPL-------------- MLBr_00955|M.leprae_Br4923 TAVRLAINTGHADVVSATPLIVMMTTLRLQDSKDSSAKS----------- . . . . Mb2073c|M.bovis_AF2122/97 ALPGSDLSR-- Rv2047c|M.tuberculosis_H37Rv ALPGSDLSR-- MMAR_3024|M.marinum_M SVTQSDPADLA MUL_2265|M.ulcerans_Agy99 SVTQSDPADLA Mflv_0493|M.gilvum_PYR-GCK ----------- Mvan_1818|M.vanbaalenii_PYR-1 ----------- MAV_1955|M.avium_104 ----------- TH_4555|M.thermoresistible__bu ----------- MSMEG_3934|M.smegmatis_MC2_155 ----------- MLBr_00955|M.leprae_Br4923 -----------