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M. avium 104 MAV_1955 (-)

annotation: PEP-utilizing protein
coordinates: 1944417 - 1946024
length: 535

MIGPIAELTDPIRGESAPDRLWTLTNVGEATPDILSPLCWSLWGTGVEFASRGGLYDFGVLPASALVVPN
DPNQWSTACFFGRQAMNVDRARELAGLLPGMTGDDFERDLLGSVRPDATPTKSDPKRLPVAAVKTPWVLL
RSRSAARDAHSAQMSWWRATVLGGDSKDPKALLADSVQRFSSVMRVHVRSRMILNALRSQVESIVGKLGC
SDLVPVLLAGYGGVIETELADDVWSLGQGRLSMDEFLLRHGFHGPNEGNVIGHSWREDHDAVKRAAQAHA
GRAEEERPSVRVQRAVAARQRAEAELLATLSLPRRLMLRKLLSFTGAHVRAVELGKAGFLTAIDGCRAAA
AALGRDLVRAGILERPDDTCYLTVEELLAPLPSNVRELVDFRRARREEYRRIEVPTVFTGMPVPIDPGGA
SAGQDAAVRGMPAGTGVFEGTVRVVLDAESDDTLDDGEVLVCKMVDPGWTALVSLAGALVTDIGSPASHG
AIVARELGIACVVGTGNGTRVLHTGDVVRVDGVTGEIAVLQRAES
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_1955--100% (535)PEP-utilizing protein
M. avium 104MAV_5056-5e-8132.77% (537) PEP-utilizing protein
M. avium 104MAV_5062-9e-6937.27% (381) pyruvate, water dikinase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2073c-7e-3336.10% (277) hypothetical protein Mb2073c
M. gilvum PYR-GCKMflv_0493-4e-3729.30% (570) pyruvate, water dikinase
M. tuberculosis H37RvRv2047c-7e-3336.10% (277) hypothetical protein Rv2047c
M. leprae Br4923MLBr_00955ppdK4e-0935.64% (101) pyruvate phosphate dikinase
M. abscessus ATCC 19977-----
M. marinum MMMAR_3024-3e-3436.63% (273) hypothetical protein MMAR_3024
M. smegmatis MC2 155MSMEG_3934-5e-2246.85% (111) phosphoenolpyruvate synthase
M. thermoresistible (build 8)TH_4555-2e-2530.79% (302) PUTATIVE putative phosphoenolpyruvate synthase
M. ulcerans Agy99MUL_2265-2e-3436.26% (273) hypothetical protein MUL_2265
M. vanbaalenii PYR-1Mvan_1818-1e-3427.02% (581) pyruvate, water dikinase

CLUSTAL 2.0.9 multiple sequence alignment


Mb2073c|M.bovis_AF2122/97           MRIAVTGASGVLGRGLTARLLSQGHEVVGIARHRPDSWPSSADFIAADIR
Rv2047c|M.tuberculosis_H37Rv        MRIAVTGASGVLGRGLTARLLSQGHEVVGIARHRPDSWPSSADFIAADIR
MMAR_3024|M.marinum_M               MRVAVTGAGGVLGRGLASRLLSQGHEVVGMSRRRPDSWPSQADFVAGDIR
MUL_2265|M.ulcerans_Agy99           MRVAVTGAGGVLGRGLASRLLSQGHEVVGMSRRRPDSWPSQADFVAGDIR
Mflv_0493|M.gilvum_PYR-GCK          -------------------MFDASSRIVDLADVLDDSFGGKALGLAELTR
Mvan_1818|M.vanbaalenii_PYR-1       ----------------------MAPATIEFDDVTDDRFGGKAAGLAELRR
MAV_1955|M.avium_104                --------------------------------------------------
TH_4555|M.thermoresistible__bu      -MMTDMSAVTSPNTVEAEHTVSNVIRFADPGATDPRLVGGKGMNLGELVA
MSMEG_3934|M.smegmatis_MC2_155      ---------------MDIMSDRYVRTLDILTIADAEEAGGKGANLGELVA
MLBr_00955|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2073c|M.bovis_AF2122/97           DATAVESAMTGADVVAHCAWVRG--R------NDHINIDGTANVLKAMAE
Rv2047c|M.tuberculosis_H37Rv        DATAVESAMTGADVVAHCAWVRG--R------NDHINIDGTANVLKAMAE
MMAR_3024|M.marinum_M               DAAAVRRAITGADVVAHCAWARN--PGPDGRISQQINIDGTRNVLDAMAA
MUL_2265|M.ulcerans_Agy99           DAAAVRRAITGADVVAHCAWARN--PGPDGRISQQINIDGTRNVLDAMAA
Mflv_0493|M.gilvum_PYR-GCK          LGLPVPPGFVIADASGTS------------------LGDAVTERFSRMRA
Mvan_1818|M.vanbaalenii_PYR-1       IGLSVPVGFVIADASAHG------------------ALDAAVDRFCQMAA
MAV_1955|M.avium_104                --------------------------------------------------
TH_4555|M.thermoresistible__bu      AGFRVPNGFTVSTEAYAATLADS--GAADRIFELLKGLDVADLARLESTA
MSMEG_3934|M.smegmatis_MC2_155      ADLPVPHGFVVMRSAYLDSVRMGGVEAELAALHTEALTHAADTARLSELC
MLBr_00955|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2073c|M.bovis_AF2122/97           TGTGRIVFTSS-------------------------GHQPRVEQMLADCG
Rv2047c|M.tuberculosis_H37Rv        TGTGRIVFTSS-------------------------GHQPRVEQMLADCG
MMAR_3024|M.marinum_M               CGTGRIVFPSSPHVYRPGVPMPATEHGAVAPASAEGRHKAGVEQMLQESG
MUL_2265|M.ulcerans_Agy99           CGTGRIVFPSSPHVYRPGLPMPATEHGAVAPASAEGRHKAGVEQMLQESG
Mflv_0493|M.gilvum_PYR-GCK          AGQTPVAVRSS--------------------------------AAGEDGA
Mvan_1818|M.vanbaalenii_PYR-1       EGVTPVAVRSS--------------------------------AVGEDGE
MAV_1955|M.avium_104                --------------------------------------------------
TH_4555|M.thermoresistible__bu      AAIRDVVTAVELPDKLAHDIERAYTELG-----ADVYVAVRSSGTAEDTA
MSMEG_3934|M.smegmatis_MC2_155      RRMQSLVNKAGLSPSVRDATLAAYRALG-----TDVVVAVRSSATGEDGR
MLBr_00955|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2073c|M.bovis_AF2122/97           LEWVAVRCALIFGRNVDNWVQRLFALPVLPAGYADRVV-QVVHSDDAQRL
Rv2047c|M.tuberculosis_H37Rv        LEWVAVRCALIFGRNVDNWVQRLFALPVLPAGYADRVV-QVVHSDDAQRL
MMAR_3024|M.marinum_M               AQWVAVRSALIVGRNIDNWVRRLFALPAFPDGSADDVL-QVVHLDDVLRL
MUL_2265|M.ulcerans_Agy99           AQWVAVRSALIVGRNIDNWVRRLFALPAFPDGSADDVL-QVVHLDDVLRL
Mflv_0493|M.gilvum_PYR-GCK          EHSFAGQYDTVLG---VGSVDELTAAVEKCVRSAGSER-AAAYQDGGAAA
Mvan_1818|M.vanbaalenii_PYR-1       DQSFAGQYDTVLG---VASVDDFTAAVRRCAGSVASQR-ASSYS-GHSPA
MAV_1955|M.avium_104                --------------------------------------------------
TH_4555|M.thermoresistible__bu      EASFAGMHDTYLDIRGTGEVLDAVRRCWASMWTARAVAYREEHGFDHREA
MSMEG_3934|M.smegmatis_MC2_155      DASFAGMNRTITNVMGEVALLDAVTQCWMSLFSPRVITYRASRGFTAAP-
MLBr_00955|M.leprae_Br4923          ----------MPGQSHKEPHRRATSTPRSLKQATSELRWALSLAAPESPA
                                                                                      

Mb2073c|M.bovis_AF2122/97           LVRALLDTVIDSGPVNLAAPGELTFRRIAAALGRPMVPIGSPVLRRVTSF
Rv2047c|M.tuberculosis_H37Rv        LVRALLDTVIDSGPVNLAAPGELTFRRIAAALGRPMVPIGSPVLRRVTSF
MMAR_3024|M.marinum_M               LTRAVSDVGAGTGPVNLAAPGLPTLREIAMALRRPILPVG-AVLRRIGSV
MUL_2265|M.ulcerans_Agy99           LTRAVSDVGAGTGPVNLAAPGLPTLREIATALRRPILPVG-AALRRIGSV
Mflv_0493|M.gilvum_PYR-GCK          RMHLVVQQMVDARAAGVVFTADPTSGRRDLLVIDAVRGLGESLVDGSTAS
Mvan_1818|M.vanbaalenii_PYR-1       TMHVVVQQMVDARAAGVVFTADPATGRRDLMVIDAIAGLGEALVDGSASP
MAV_1955|M.avium_104                --------------------------------------------------
TH_4555|M.thermoresistible__bu      KIAVVVQTMAEADVSGVMYTANPLNNRTDEIVINSAYGLGESIVSGAINP
MSMEG_3934|M.smegmatis_MC2_155      AMAVVVQQMLSADRAGVAFTSDPSTGDADHIVIEAAFGQGEVVVSGKVEP
MLBr_00955|M.leprae_Br4923          FMRHLLGNAHDKVDITTSSEHVAAFTEHAIVLLNGNAHQTRELLGGKGYN
                                                                                      

Mb2073c|M.bovis_AF2122/97           AELELLHSAPLMDVTLLRD----------------------RWGFQPAWN
Rv2047c|M.tuberculosis_H37Rv        AELELLHSAPLMDVTLLRD----------------------RWGFQPAWN
MMAR_3024|M.marinum_M               AEFQLVQGVPVMDTARLHD----------------------EWKFQPAFT
MUL_2265|M.ulcerans_Agy99           AEFQLVQGVPVMDTARLHD----------------------EWKFQPAFT
Mflv_0493|M.gilvum_PYR-GCK          DHFVLTHAG-----DTVTT----------------------EASSQPALA
Mvan_1818|M.vanbaalenii_PYR-1       DHVVLNADG-----STAVR----------------------EVGTAPVLS
MAV_1955|M.avium_104                --------------------------------------------------
TH_4555|M.thermoresistible__bu      DEFTVDLGTLKIKQANVGNKKEKIVRAPDKPSGTVTLAVSEEDAGRLSLT
MSMEG_3934|M.smegmatis_MC2_155      DTYVIDKRT-----------------------------------------
MLBr_00955|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2073c|M.bovis_AF2122/97           AEECLEDFTLAVRGRIGLGKRTFSLPWRLANIQDLPAVDSPADDGVAPRL
Rv2047c|M.tuberculosis_H37Rv        AEECLEDFTLAVRGRIGLGKRTFSLPWRLANIQDLPAVDSPADDGVAPRL
MMAR_3024|M.marinum_M               AEESVEDFALAVRGRVSLGRRVVSLPWRLANIQDLPAVDAPAQDGVVPRL
MUL_2265|M.ulcerans_Agy99           AEESVEDFALAVRGRVSLGRRVVSLPWRLANIQDLPAIDASAQDGVVPRL
Mflv_0493|M.gilvum_PYR-GCK          DDEIDRIRTGALLAAAHWG-RPLDLEWAIDRDGLLWWLQARPITTLP---
Mvan_1818|M.vanbaalenii_PYR-1       SDDVAEIRSGALRAARHWG-RPLDLEWAIDGTGKLWWLQARPITTLP---
MAV_1955|M.avium_104                --------------------------------------------------
TH_4555|M.thermoresistible__bu      DEQVAELAALGRQVMDHYGGLPQDIEWACVDG-EFFLLQTRPITGAK---
MSMEG_3934|M.smegmatis_MC2_155      ----------LEVRDVRIGFKAIKIVRGDDGADSMVQLER----------
MLBr_00955|M.leprae_Br4923          ------------INAMRRHQLAVPPAFCITTEVGVRYLAAP---------
                                                                                      

Mb2073c|M.bovis_AF2122/97           AGPEGANGEFDTPIDP---RFPTYLATNLSEALPGPFSPSSASVTVRGLR
Rv2047c|M.tuberculosis_H37Rv        AGPEGANGEFDTPIDP---RFPTYLATNLSEALPGPFSPSSASVTVRGLR
MMAR_3024|M.marinum_M               AGPEGVNGEFDTPIDP---RFPTFLATNLSEALPGPFSPSSASVTVRGLR
MUL_2265|M.ulcerans_Agy99           AGPEGVNGEFDTPIDP---RFPTFLATNLSEALPGPFSPSSASVTVRGLR
Mflv_0493|M.gilvum_PYR-GCK          ----GDPNEMDTPVTG---PTHVYTRCNIGEMMPGAFCPLTASVSGHAID
Mvan_1818|M.vanbaalenii_PYR-1       ----GDLNEMDSPVAG---SDHVYTRCNIGEMMPGAFCPLTASVSGYAID
MAV_1955|M.avium_104                --MIGPIAELTDPIRGESAPDRLWTLTNVGEATPDILSPLCWSLWGTGVE
TH_4555|M.thermoresistible__bu      ---FTWPEGFNDWQNGPEDPDTLWTFKYAEQYWTGGITPLFFSVRARETQ
MSMEG_3934|M.smegmatis_MC2_155      -------SQAEARVLDDDALRKIATLAVATETHNGCPQDIEWVIADGAVW
MLBr_00955|M.leprae_Br4923          -------TPTMEAIWNDVLDQMRWLEAETSRTFGWGPRPLLVSIRSGAVQ
                                                                  .            :      

Mb2073c|M.bovis_AF2122/97           AGGVGIAERLRPS-----GVIQREIAMRTVAVFAHRLYGAITSAHFMAAT
Rv2047c|M.tuberculosis_H37Rv        AGGVGIAERLRPS-----GVIQREIAMRTVAVFAHRLYGAITSAHFMAAT
MMAR_3024|M.marinum_M               AGGVGIAERLRPG-----GVIQREIAMRTVAVFAHRLYGAITSAHFMAET
MUL_2265|M.ulcerans_Agy99           AGGVGIAERLRPG-----GVIQREIAMRTVAVFAHRLYGAITSAHFMAET
Mflv_0493|M.gilvum_PYR-GCK          Y-AMQMVQVAGGV-----QERYEDRARQVGYFFGHMFLNMTEGTALSSGI
Mvan_1818|M.vanbaalenii_PYR-1       Y-AMQMTQVVARA-----QPRYEKPWLQVGYFYGHMFLNLTEGTALSSGI
MAV_1955|M.avium_104                FASRGGLYDFGVLPASALVVPNDPNQWSTACFFGRQAMNVDRARELAGLL
TH_4555|M.thermoresistible__bu      VGYDRMNARAGFQ------DLLGQRLYKDKYGTVYWNVDMDE-KRLRYVL
MSMEG_3934|M.smegmatis_MC2_155      LVQARPITTLGSAG----STAGDEPSVLIRGLPAAPGVASGRVRVLLAPD
MLBr_00955|M.leprae_Br4923          SMPGMMDTILNLG----------------INDPVEQALAAASPSPIPQTF
                                                                                 :    

Mb2073c|M.bovis_AF2122/97           VPFAKPATIVSNSGFFGPSMASLPIFGAQRPPSESS-RARRWLRTLRNIG
Rv2047c|M.tuberculosis_H37Rv        VPFAKPATIVSNSGFFGPSMASLPIFGAQRPPSESS-RARRWLRTLRNIG
MMAR_3024|M.marinum_M               VPFAKPAMIVSNSGFFGPSMGSLPIFGEERPPAESS-FVRRQLRTVRNIG
MUL_2265|M.ulcerans_Agy99           VPFAKPAMIVSNSGFFGPSMGSLPIFGEERPPAESS-FVRRQLCTVRNIG
Mflv_0493|M.gilvum_PYR-GCK          LGNSLEQFSLSVCGRVIDELEPGPPKPFVRKLINTVRLSTFALSSAPAIR
Mvan_1818|M.vanbaalenii_PYR-1       LGNSREQFSMSICGRVVDELEAKPPRPFARKLVNTVRLTSHALSAGPAIR
MAV_1955|M.avium_104                PGMTGDDFERDLLGSVRPDATPTKSDP-KRLPVAAVKTPWVLLRSRSAAR
TH_4555|M.thermoresistible__bu      PRFARPAGANVVPADMQEQMFAEPLDVVRWLKAMISFSVSPIYSLSRWKK
MSMEG_3934|M.smegmatis_MC2_155      DGDKLTDGEILVAPTTNPDWLP----TIRRAAALVTETGGMTCHAAIVAR
MLBr_00955|M.leprae_Br4923          ARDTRLRFIRTYR-RIVDPLNPPPANTYDQLRAAIESIFSSWNSPRAVAY
                                                         .                            

Mb2073c|M.bovis_AF2122/97           VFGVNLVGLSAGSPRDTDAYVADVDRLERLAFDNLATHDDRRLLSLILLA
Rv2047c|M.tuberculosis_H37Rv        VFGVNLVGLSAGSPRDTDAYVADVDRLERLAFDNLATHDDRRLLSLILLA
MMAR_3024|M.marinum_M               VFGVNLVGLSAGSALDTNDFIADVDRLEQLAGGDVTTLDDRRLLSLILLA
MUL_2265|M.ulcerans_Agy99           VFGVNLVGLSAGSALDTNDFIADVDRLEQLAGGDVTTLDDRRLLSLILLA
Mflv_0493|M.gilvum_PYR-GCK          RLPQTIAAFPPITSRDPAVVLRHLE-------AGVDIYREVTLIHVRSSS
Mvan_1818|M.vanbaalenii_PYR-1       RLADQIAGWPIPSHEDARLVLQQLE-------SGVQLYCDVTLTHVRSSS
MAV_1955|M.avium_104                DAHSAQMSWWRATVLGGDS-------------KDPKALLADSVQRFSSVM
TH_4555|M.thermoresistible__bu      VIREDYLFNEAAVAKANGLSDAELRALSDDELYRYQRDLQEYAIDFMDPL
MSMEG_3934|M.smegmatis_MC2_155      ELGVPCVVGARSAT---------------------VALAVGSMVTVDGTR
MLBr_00955|M.leprae_Br4923          RTHYGLD--------------------------DQSGTAVIVQAMVFGNQ
                                                                                 .    

Mb2073c|M.bovis_AF2122/97           RDHVVHGWVLASGSFMLCAAFNVLLRGLCGRDTAPAAGPELVSARSVEAV
Rv2047c|M.tuberculosis_H37Rv        RDHVVHGWVLASGSFMLCAAFNVLLRGLCGRDTAPAAGPELVSARSVEAV
MMAR_3024|M.marinum_M               RDHVVHGWVLASGSFMLCAAFNVLLRAVSGRDTAPAAGPELVSARSVEAV
MUL_2265|M.ulcerans_Agy99           RDHVVHGWVLASGSFMLCAAFNVLLRAVSGRDTAPAAGPELVSARSVEAV
Mflv_0493|M.gilvum_PYR-GCK          RSAVAANVLESHLVRRAAKRGASDTAGSAEAIRLMTGAG-VESALMVEEL
Mvan_1818|M.vanbaalenii_PYR-1       RAAVAANILESTLVRQAVKNGRSEEEGQAEAARLMAGASDVESAMMLDQL
MAV_1955|M.avium_104                RVHVRSRMILNALRSQVESIVGKLGCSDLVPVLLAGYGGVIETELADDVW
TH_4555|M.thermoresistible__bu      WFGAYTAMSMFFSLHAALLAKYYTGTNELLGQDLISGLPTTLQALENRAF
MSMEG_3934|M.smegmatis_MC2_155      GEVTTGRLPETVRTTTTPQEPAPHITGEATGTKVYVNLAMPDSAEAVAAQ
MLBr_00955|M.leprae_Br4923          GAYSGAGTLFSRNPITRESKLFGEWLPGGQGDDVVSGLVEVQPITSLRDE
                                                                                      

Mb2073c|M.bovis_AF2122/97           QRLVAAARRDPVVIR--LLAEPGERLDKLAVEAP--EFHSAVLAELTLIG
Rv2047c|M.tuberculosis_H37Rv        QRLVAAARRDPVVIR--LLAEPGERLDKLAVEAP--EFHSAVLAELTLIG
MMAR_3024|M.marinum_M               QRLVAAARHDEAVIR--LLSEPGDRLGKLAVAAP--HFYDAVRQELSLIG
MUL_2265|M.ulcerans_Agy99           QRLVDAARHDEAVIR--LLSEPGDRLGKLAVAAP--HFYDAVRQELSLIG
Mflv_0493|M.gilvum_PYR-GCK          TAVVSMLRRDGDAAARFLAAPAGEAVTRLRAAET--PSGAALRTFLDRHG
Mvan_1818|M.vanbaalenii_PYR-1       QSVVRAIAADSGVATRFLAAAPDVAVVELQRADN--ASGEALRQFLLRHG
MAV_1955|M.avium_104                SLGQGRLSMDEFLLRHGFHGPNEGNVIGHSWRED--HDAVKR----AAQA
TH_4555|M.thermoresistible__bu      FELTSMIRHSKVLSDAFEKHQGAAFFAELENSDEGREFLEKYREFLAEHG
MSMEG_3934|M.smegmatis_MC2_155      DVDGVGLLRAEFMLTEALAGRHPRDLITKGEQDT---LVDAMAAAVTRIG
MLBr_00955|M.leprae_Br4923          QP----TVYDELVDTAGRLERLGSDVQEIEFTTE----DSKLWLLQTRVA
                                                             .                       .

Mb2073c|M.bovis_AF2122/97           HRGPAEVEMAATSYADNPELLVRMVAKTLRAVP-----------------
Rv2047c|M.tuberculosis_H37Rv        HRGPAEVEMAATSYADNPELLVRMVAKTLRAVP-----------------
MMAR_3024|M.marinum_M               HRGPAEVEMMSTSYADNPELLVGMVAKTLSTSS-----------------
MUL_2265|M.ulcerans_Agy99           HRGPAEVEMMSTSYADNPELLVGMVAKTLSTSS-----------------
Mflv_0493|M.gilvum_PYR-GCK          HRGYRELCMRDPSWADDPDGLGAMMQVMLRGAAPE---------------
Mvan_1818|M.vanbaalenii_PYR-1       HRGYRELCMRDPSWAQDAGGLGAMMQVMVRAASSD---------------
MAV_1955|M.avium_104                HAGRAEEERPSVRVQRAVAARQRAEAELLATLS-----------------
TH_4555|M.thermoresistible__bu      HRGHPDRDLIFKRRADDPAVDYEAFKVQLQAPEATPPIELEERVRARREA
MSMEG_3934|M.smegmatis_MC2_155      TAFAPRPVIYRAMDFRTNEFRGLAGGEQFEPVEHN---------------
MLBr_00955|M.leprae_Br4923          ERSAQVAVRLALQLWQEGLIDDAEALRRVTPVH-----------------
                                                                .                     

Mb2073c|M.bovis_AF2122/97           ---------APQPPTPVIPLRAKPVALLAARQLRDREVRRDRMVRAIWVL
Rv2047c|M.tuberculosis_H37Rv        ---------APQPPTPVIPLRAKPVALLAARQLRDREVRRDRMVRAIWVL
MMAR_3024|M.marinum_M               ---------VPQPPQPSIPLQAKPIAVLAARQLRDREARRDKMVRAIWVL
MUL_2265|M.ulcerans_Agy99           ---------VPQPPQPSIPLQAKPIAVLAARQLRDREARRDKMVRAIWVL
Mflv_0493|M.gilvum_PYR-GCK          ------NPAATAPSDPAQSRTLRVLARLAQAGARGREETKSRMALMAHLL
Mvan_1818|M.vanbaalenii_PYR-1       ------RQPAHSPTEAPTSPAIRFLARLAQGGARGREETKSKMALMAHAL
MAV_1955|M.avium_104                ---------------LPRRLMLRKLLSFTGAHVRAVELGKAGFLTAIDGC
TH_4555|M.thermoresistible__bu      AEAEVIENLGRGFLGPVKQQLFKLLQHQIIDFLVLRDDWRHFIDRITYAK
MSMEG_3934|M.smegmatis_MC2_155      -------PMIGYRGCYRYIKEPDLFALELSALARAREHTPNIHLMIPFVR
MLBr_00955|M.leprae_Br4923          ---------VETVLLPVLQPENHLSATLLAKGTPTCPGVISGKAYTEVDE
                                                                                      

Mb2073c|M.bovis_AF2122/97           RALLREYGRRLTEAGVFDTPDDVFYLLVDEIDALP-----ADVSGLVARR
Rv2047c|M.tuberculosis_H37Rv        RALLREYGRRLTEAGVFDTPDDVFYLLVDEIDALP-----ADVSGLVARR
MMAR_3024|M.marinum_M               RALLREHGRRLAEAGVLHASDDVFYLLVDELDALP-----ADVAELVARR
MUL_2265|M.ulcerans_Agy99           RALLREHGRRLAEAGVLHASDDVFYLLVDEVDALP-----ADVAELVARR
Mflv_0493|M.gilvum_PYR-GCK          KRGYRHLGEVLHEAGRLPDADLVFFFDRRELPLVVSGDDVTELVHRARQR
Mvan_1818|M.vanbaalenii_PYR-1       KRGYRHLGEVLARSGRLPDADLVFFFDRSELPRVVGDDDISELVQSAVKR
MAV_1955|M.avium_104                RAAAAALGRDLVRAGILERPDDTCYLTVEELLAPLP----SNVRELVDFR
TH_4555|M.thermoresistible__bu      RKAFLEVARRCVERGRLEKEDDAFFLGETELFEVLNGTAKQPLVQAKIAA
MSMEG_3934|M.smegmatis_MC2_155      TRWELEECLALVDASPLRRHRNLHRWVMAEVPSVVH--------------
MLBr_00955|M.leprae_Br4923          ALDAAESAEQVILVRDHTRPDDVLGMLASQGVVTEVG-------------
                                                                 :                    

Mb2073c|M.bovis_AF2122/97           RA---EQRRLAGIVPPTVFSGSWEPSPSSAAALAAGDTLRGVGVCGGRVR
Rv2047c|M.tuberculosis_H37Rv        RA---EQRRLAGIVPPTVFSGSWEPSPSSAAALAAGDTLRGVGVCGGRVR
MMAR_3024|M.marinum_M               RA---EQRRLTAVVPPTVFSGKWEPSTASAAALTAGGTLRGVGVCGGRVR
MUL_2265|M.ulcerans_Agy99           RA---EQRRLTAVVPPTVFSGKWEPSTASAAALTAEGTLRGVGVCGGRVR
Mflv_0493|M.gilvum_PYR-GCK          RE---ALPFQAALEFGDVSVGRPTPIVR--AAVSGDGVVAGRPAGHGSVE
Mvan_1818|M.vanbaalenii_PYR-1       RE---ALAYQDSLEFEDVSVGRPRPVVAPPVITSTADQVVGRPASRGTVE
MAV_1955|M.avium_104                RA---RREEYRRIEVPTVFTGMPVPIDPGGASAGQDAAVRGMPAGTGVFE
TH_4555|M.thermoresistible__bu      RRPDFELFESRTFTPPMFMRGETPVDEAAPAAVAGSGAINGVGTSAGQVE
MSMEG_3934|M.smegmatis_MC2_155      -----WLPEYVGMGIDGVSIGSND-LTQLMLGVDRDSETCAELFDESDAA
MLBr_00955|M.leprae_Br4923          ----------GAASHAAVVSRELSRVAVVGCGQGTAVSLAGKQITVDGDK
                                                     .                      .     .   

Mb2073c|M.bovis_AF2122/97           GRVRIVR-PETIDDLQPGEILVAEVTDVG-YTAAFCYAAAVVTELGGPMS
Rv2047c|M.tuberculosis_H37Rv        GRVRIVR-PETIDDLQPGEILVAEVTDVG-YTAAFCYAAAVVTELGGPMS
MMAR_3024|M.marinum_M               GRVRIVR-PETIDELEPGEILVAEVTDVG-YTAAFCYAAAVVTELGGPMS
MUL_2265|M.ulcerans_Agy99           GRVRIVR-PETIDELEPGEILVAEVTDVG-YTAAFCYAAAVVTELGGPMS
Mflv_0493|M.gilvum_PYR-GCK          GVVRVARSVVEARDLQPGEILVAPVTDVG-WTPYFAVIAALVTDIGSSVS
Mvan_1818|M.vanbaalenii_PYR-1       GTVRVAKTIQDARDVQRGEILVAPVTDVG-WTPYFTVIAALITDIGSSVS
MAV_1955|M.avium_104                GTVRVVLDAESDDTLDDGEVLVCKMVDPG-WTALVSLAGALVTDIGSPAS
TH_4555|M.thermoresistible__bu      GRARVLASMTEIGTLEQGDVLVCNATDPG-WSPVFGVISGLIIETGGMLA
MSMEG_3934|M.smegmatis_MC2_155      VLDAISRIISTANRLGITSSLCGQAPSTR-PEFAEHLVRMGITSVSVNPD
MLBr_00955|M.leprae_Br4923          GEVRQGNLTLSAWSENETPELRELADIARRISPLRVHMTEDHTRLDDSSD
                                                        *                        .    

Mb2073c|M.bovis_AF2122/97           HAAVVAREFGFPCVVDAQGATRFLPPGALVEVDGATGEIHVVELASEDGP
Rv2047c|M.tuberculosis_H37Rv        HAAVVAREFGFPCVVDAQGATRFLPPGALVEVDGATGEIHVVELASEDGP
MMAR_3024|M.marinum_M               HAAVVAREFGFPCVVDAQGATRFLPPGALIEVDGTTGEIQVLELAAEGDS
MUL_2265|M.ulcerans_Agy99           HAAVVAREFGFPCVVDAQGATRFLPPGALIEVDGTTGEIQVLELAAEGDS
Mflv_0493|M.gilvum_PYR-GCK          HGAVVAREYGLPCVVNTLVGTQVLRTGDRVRVDGDRGLVTVLDSP-----
Mvan_1818|M.vanbaalenii_PYR-1       HGAVVAREYGLPCVVNTLVGTQVLRTGDRVRVDGDRGVVTRLG-------
MAV_1955|M.avium_104                HGAIVARELGIACVVGTGNGTRVLHTGDVVRVDGVTGEIAVLQRAES---
TH_4555|M.thermoresistible__bu      HGACLSREHGIPAVQIVG-ATQIIPDGAYVRINGTTGLVEVLEPAPAGAA
MSMEG_3934|M.smegmatis_MC2_155      AAGAARRAVAAAERRLLLDSVRHPRHAPTASPRNPL--------------
MLBr_00955|M.leprae_Br4923          TAVRLAINTGHADVVSATPLIVMMTTLRLQDSKDSSAKS-----------
                                     .       . .                     .                

Mb2073c|M.bovis_AF2122/97           ALPGSDLSR--
Rv2047c|M.tuberculosis_H37Rv        ALPGSDLSR--
MMAR_3024|M.marinum_M               SVTQSDPADLA
MUL_2265|M.ulcerans_Agy99           SVTQSDPADLA
Mflv_0493|M.gilvum_PYR-GCK          -----------
Mvan_1818|M.vanbaalenii_PYR-1       -----------
MAV_1955|M.avium_104                -----------
TH_4555|M.thermoresistible__bu      -----------
MSMEG_3934|M.smegmatis_MC2_155      -----------
MLBr_00955|M.leprae_Br4923          -----------