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APATIEFDDVTDDRFGGKAAGLAELRRIGLSVPVGFVIADASAHGALDAAVDRFCQMAAEGVTPVAVRSS AVGEDGEDQSFAGQYDTVLGVASVDDFTAAVRRCAGSVASQRASSYSGHSPATMHVVVQQMVDARAAGVV FTADPATGRRDLMVIDAIAGLGEALVDGSASPDHVVLNADGSTAVREVGTAPVLSSDDVAEIRSGALRAA RHWGRPLDLEWAIDGTGKLWWLQARPITTLPGDLNEMDSPVAGSDHVYTRCNIGEMMPGAFCPLTASVSG YAIDYAMQMTQVVARAQPRYEKPWLQVGYFYGHMFLNLTEGTALSSGILGNSREQFSMSICGRVVDELEA KPPRPFARKLVNTVRLTSHALSAGPAIRRLADQIAGWPIPSHEDARLVLQQLESGVQLYCDVTLTHVRSS SRAAVAANILESTLVRQAVKNGRSEEEGQAEAARLMAGASDVESAMMLDQLQSVVRAIAADSGVATRFLA AAPDVAVVELQRADNASGEALRQFLLRHGHRGYRELCMRDPSWAQDAGGLGAMMQVMVRAASSDRQPAHS PTEAPTSPAIRFLARLAQGGARGREETKSKMALMAHALKRGYRHLGEVLARSGRLPDADLVFFFDRSELP RVVGDDDISELVQSAVKRREALAYQDSLEFEDVSVGRPRPVVAPPVITSTADQVVGRPASRGTVEGTVRV AKTIQDARDVQRGEILVAPVTDVGWTPYFTVIAALITDIGSSVSHGAVVAREYGLPCVVNTLVGTQVLRT GDRVRVDGDRGVVTRLG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1818 | - | - | 100% (788) | pyruvate, water dikinase |
| M. vanbaalenii PYR-1 | Mvan_2632 | - | 1e-59 | 29.00% (869) | pyruvate, water dikinase |
| M. vanbaalenii PYR-1 | Mvan_4106 | - | 1e-21 | 29.93% (274) | phosphoenolpyruvate synthase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2073c | - | 1e-26 | 27.60% (576) | hypothetical protein Mb2073c |
| M. gilvum PYR-GCK | Mflv_0493 | - | 0.0 | 68.33% (783) | pyruvate, water dikinase |
| M. tuberculosis H37Rv | Rv2047c | - | 1e-26 | 27.60% (576) | hypothetical protein Rv2047c |
| M. leprae Br4923 | MLBr_00955 | ppdK | 3e-06 | 30.43% (115) | pyruvate phosphate dikinase |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_3024 | - | 2e-31 | 26.74% (804) | hypothetical protein MMAR_3024 |
| M. avium 104 | MAV_5056 | - | 1e-34 | 26.64% (563) | PEP-utilizing protein |
| M. smegmatis MC2 155 | MSMEG_3934 | - | 1e-28 | 33.01% (312) | phosphoenolpyruvate synthase |
| M. thermoresistible (build 8) | TH_3290 | - | 2e-45 | 26.50% (815) | PUTATIVE putative phosphoenolpyruvate synthase |
| M. ulcerans Agy99 | MUL_2265 | - | 9e-32 | 26.81% (817) | hypothetical protein MUL_2265 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1818|M.vanbaalenii_PYR-1 ----------------------MAPATIEFDDVTDDRFGGKAAGLAELRR
Mflv_0493|M.gilvum_PYR-GCK -------------------MFDASSRIVDLADVLDDSFGGKALGLAELTR
Mb2073c|M.bovis_AF2122/97 MRIAVTGASGVLGRGLTARLLSQGHEVVGIARHRPDSWPSSADFIAADIR
Rv2047c|M.tuberculosis_H37Rv MRIAVTGASGVLGRGLTARLLSQGHEVVGIARHRPDSWPSSADFIAADIR
MMAR_3024|M.marinum_M MRVAVTGAGGVLGRGLASRLLSQGHEVVGMSRRRPDSWPSQADFVAGDIR
MUL_2265|M.ulcerans_Agy99 MRVAVTGAGGVLGRGLASRLLSQGHEVVGMSRRRPDSWPSQADFVAGDIR
TH_3290|M.thermoresistible__bu ------------MPNIVQINSAATDSAASAQLTERALVGGKGRHLMLCSA
MAV_5056|M.avium_104 --------------------------------------------------
MSMEG_3934|M.smegmatis_MC2_155 ---------------MDIMSDRYVRTLDILTIADAEEAGGKGANLGELVA
MLBr_00955|M.leprae_Br4923 --------------------------------------------------
Mvan_1818|M.vanbaalenii_PYR-1 IGLSVPVGFVIADASAHG--------------------------ALDAAV
Mflv_0493|M.gilvum_PYR-GCK LGLPVPPGFVIADASGTS--------------------------LGDAVT
Mb2073c|M.bovis_AF2122/97 DATAVESAMTGADVVAHCAWVRGR----------------NDHINIDGTA
Rv2047c|M.tuberculosis_H37Rv DATAVESAMTGADVVAHCAWVRGR----------------NDHINIDGTA
MMAR_3024|M.marinum_M DAAAVRRAITGADVVAHCAWARNPGPD----------GRISQQINIDGTR
MUL_2265|M.ulcerans_Agy99 DAAAVRRAITGADVVAHCAWARNPGPD----------GRISQQINIDGTR
TH_3290|M.thermoresistible__bu AGFPVPPGFTITTDAYDAFLAHNKLTDTVAKSA--AAFVYHDVDTLEQQA
MAV_5056|M.avium_104 --------------------------------------------------
MSMEG_3934|M.smegmatis_MC2_155 ADLPVPHGFVVMRSAYLDSVRMGGVEAELAALHTEALTHAADTARLSELC
MLBr_00955|M.leprae_Br4923 --------------------------------------------------
Mvan_1818|M.vanbaalenii_PYR-1 DRFCQMAAEGVTPVAVRSS-------------------------------
Mflv_0493|M.gilvum_PYR-GCK ERFSRMRAAGQTPVAVRSS-------------------------------
Mb2073c|M.bovis_AF2122/97 NVLKAMAETGTGRIVFTSS-------------------------GHQPRV
Rv2047c|M.tuberculosis_H37Rv NVLKAMAETGTGRIVFTSS-------------------------GHQPRV
MMAR_3024|M.marinum_M NVLDAMAACGTGRIVFPSSPHVYRPGVPMPATEHGAVAPASAEGRHKAGV
MUL_2265|M.ulcerans_Agy99 NVLDAMAACGTGRIVFPSSPHVYRPGLPMPATEHGAVAPASAEGRHKAGV
TH_3290|M.thermoresistible__bu TAIQEVILNGQIPPALAEEVAARYSELG---------------GYVAVRS
MAV_5056|M.avium_104 --------------------------------------------------
MSMEG_3934|M.smegmatis_MC2_155 RRMQSLVNKAGLSPSVRDATLAAYRALG-------------TDVVVAVRS
MLBr_00955|M.leprae_Br4923 --------------------------------------------------
Mvan_1818|M.vanbaalenii_PYR-1 -AVGEDGEDQSFAGQYDTVLG---VASVDDFTAAVRRCAGSVASQRASSY
Mflv_0493|M.gilvum_PYR-GCK -AAGEDGAEHSFAGQYDTVLG---VGSVDELTAAVEKCVRSAGSERAAAY
Mb2073c|M.bovis_AF2122/97 EQMLADCGLEWVAVRCALIFGRNVDNWVQRLFALPVLPAGYADRVVQVVH
Rv2047c|M.tuberculosis_H37Rv EQMLADCGLEWVAVRCALIFGRNVDNWVQRLFALPVLPAGYADRVVQVVH
MMAR_3024|M.marinum_M EQMLQESGAQWVAVRSALIVGRNIDNWVRRLFALPAFPDGSADDVLQVVH
MUL_2265|M.ulcerans_Agy99 EQMLQESGAQWVAVRSALIVGRNIDNWVRRLFALPAFPDGSADDVLQVVH
TH_3290|M.thermoresistible__bu SGTAEDMADASFAGLHDTFLD---ITGEDALLEAVKKCWASLWTSRAIAY
MAV_5056|M.avium_104 -------------------------------------------MTPRACE
MSMEG_3934|M.smegmatis_MC2_155 SATGEDGRDASFAGMNRTITN---VMGEVALLDAVTQCWMSLFSPRVITY
MLBr_00955|M.leprae_Br4923 --MPGQSHKEPHRRATSTPRSLKQATSELRWALSLAAPESPAFMRHLLGN
Mvan_1818|M.vanbaalenii_PYR-1 S-GHSPAT-----MHVVVQQMVDARAAGVVFTADPATGRRDLMVIDAIAG
Mflv_0493|M.gilvum_PYR-GCK QDGGAAAR-----MHLVVQQMVDARAAGVVFTADPTSGRRDLLVIDAVRG
Mb2073c|M.bovis_AF2122/97 SDDAQRLL-----VRALLDTVIDSGPVNLAAPGELTFRRIAAALGRPMVP
Rv2047c|M.tuberculosis_H37Rv SDDAQRLL-----VRALLDTVIDSGPVNLAAPGELTFRRIAAALGRPMVP
MMAR_3024|M.marinum_M LDDVLRLL-----TRAVSDVGAGTGPVNLAAPGLPTLREIAMALRRPILP
MUL_2265|M.ulcerans_Agy99 LDDVLRLL-----TRAVSDVGAGTGPVNLAAPGLPTLREIATALRRPILP
TH_3290|M.thermoresistible__bu RGEQGHAPGALPKLAVVVQQMVEADAAGVMFTANPLTSNTDEIVVNSCWG
MAV_5056|M.avium_104 TRRMLMAS-----MPSASAILTAARTTASRLSPARLIRRHHLPRLAWTRP
MSMEG_3934|M.smegmatis_MC2_155 RASRGFTAAP--AMAVVVQQMLSADRAGVAFTSDPSTGDADHIVIEAAFG
MLBr_00955|M.leprae_Br4923 AHDKVDIT--------TSSEHVAAFTEHAIVLLNGNAHQTRELLGGKGYN
:
Mvan_1818|M.vanbaalenii_PYR-1 LGEALVDGSASPDHVVLNADG-----STAVREVGTAP-------------
Mflv_0493|M.gilvum_PYR-GCK LGESLVDGSTASDHFVLTHAG-----DTVTTEASSQP-------------
Mb2073c|M.bovis_AF2122/97 IGSPVLRRVTSFAELELLHSAPLMDVTLLRDRWGFQP-------------
Rv2047c|M.tuberculosis_H37Rv IGSPVLRRVTSFAELELLHSAPLMDVTLLRDRWGFQP-------------
MMAR_3024|M.marinum_M VG-AVLRRIGSVAEFQLVQGVPVMDTARLHDEWKFQP-------------
MUL_2265|M.ulcerans_Agy99 VG-AALRRIGSVAEFQLVQGVPVMDTARLHDEWKFQP-------------
TH_3290|M.thermoresistible__bu LGEGLVSGIVNPDQFVLGKDRLAIKERMLGDKAVTVKRNPDGPDSTVSVP
MAV_5056|M.avium_104 CGAATIRRRLHFLSHVQKVTG-------VSMRSHSAP-------------
MSMEG_3934|M.smegmatis_MC2_155 QGEVVVSGKVEPDTYVIDKRTLEVRDVRIGFKAIKIVR------------
MLBr_00955|M.leprae_Br4923 INAMRRHQLAVPPAFCITTEVG------VRYLAAPTP-------------
.
Mvan_1818|M.vanbaalenii_PYR-1 ---------VLSSDDVAEIRSGALRAARHWG-RPLDLEWAIDGTGKLWWL
Mflv_0493|M.gilvum_PYR-GCK ---------ALADDEIDRIRTGALLAAAHWG-RPLDLEWAIDRDGLLWWL
Mb2073c|M.bovis_AF2122/97 ---------AWNAEECLEDFTLAVRGRIGLGKRTFSLPWRLANIQDLPAV
Rv2047c|M.tuberculosis_H37Rv ---------AWNAEECLEDFTLAVRGRIGLGKRTFSLPWRLANIQDLPAV
MMAR_3024|M.marinum_M ---------AFTAEESVEDFALAVRGRVSLGRRVVSLPWRLANIQDLPAV
MUL_2265|M.ulcerans_Agy99 ---------AFTAEESVEDFALAVRGRVSLGRRVVSLPWRLANIQDLPAI
TH_3290|M.thermoresistible__bu TPEPKREAWSIADDTVVRLGELARRIERYFDGLPQDIEWAVKD-NEIFVL
MAV_5056|M.avium_104 --------------------------------------------------
MSMEG_3934|M.smegmatis_MC2_155 -----------GDDGADSMVQLER--------------------------
MLBr_00955|M.leprae_Br4923 --------------------------------------------------
Mvan_1818|M.vanbaalenii_PYR-1 QARPITTLP-------GDLNEMDSPVAGSDHVYTRCNIGEMMPGAFCPLT
Mflv_0493|M.gilvum_PYR-GCK QARPITTLP-------GDPNEMDTPVTGPTHVYTRCNIGEMMPGAFCPLT
Mb2073c|M.bovis_AF2122/97 DSPADDGVAPRLAGPEGANGEFDTPIDPRFPTYLATNLSEALPGPFSPSS
Rv2047c|M.tuberculosis_H37Rv DSPADDGVAPRLAGPEGANGEFDTPIDPRFPTYLATNLSEALPGPFSPSS
MMAR_3024|M.marinum_M DAPAQDGVVPRLAGPEGVNGEFDTPIDPRFPTFLATNLSEALPGPFSPSS
MUL_2265|M.ulcerans_Agy99 DASAQDGVVPRLAGPEGVNGEFDTPIDPRFPTFLATNLSEALPGPFSPSS
TH_3290|M.thermoresistible__bu QSRAITGVDFT---WDSDVDAWQEAEDEPEAIWTRKFADEFWTGPITPLF
MAV_5056|M.avium_104 ---------------EHNAANALHSMSPPGATWSSVNLAEAVPGVMTPLC
MSMEG_3934|M.smegmatis_MC2_155 ----------------SQAEARVLDDDALRKIATLAVATETHNGCPQDIE
MLBr_00955|M.leprae_Br4923 ------------------TMEAIWNDVLDQMRWLEAETSRTFGWGPRPLL
.
Mvan_1818|M.vanbaalenii_PYR-1 ASVSGYAIDY-AMQMTQVVARAQPRYEKPWLQVGYFYGHMFLNLTEGTAL
Mflv_0493|M.gilvum_PYR-GCK ASVSGHAIDY-AMQMVQVAGGVQERYEDRARQVGYFFGHMFLNMTEGTAL
Mb2073c|M.bovis_AF2122/97 ASVTVRGLRAGGVGIAERLRPSGVIQREIAMRTVAVFAHRLYGAITSAHF
Rv2047c|M.tuberculosis_H37Rv ASVTVRGLRAGGVGIAERLRPSGVIQREIAMRTVAVFAHRLYGAITSAHF
MMAR_3024|M.marinum_M ASVTVRGLRAGGVGIAERLRPGGVIQREIAMRTVAVFAHRLYGAITSAHF
MUL_2265|M.ulcerans_Agy99 ASVTVRGLRAGGVGIAERLRPGGVIQREIAMRTVAVFAHRLYGAITSAHF
TH_3290|M.thermoresistible__bu YSVRARGFTNAGVRSALDWGFADVAAKR---RHKYFKAEVYTNSEYQKAL
MAV_5056|M.avium_104 ASVWVPASELGLREPFVAMGALPVDRGGIPADPAERITNAFFGRMAVRVD
MSMEG_3934|M.smegmatis_MC2_155 WVIADGAVWLVQARPITTLGSAGS-------TAGDEPSVLIRGLPAAPGV
MLBr_00955|M.leprae_Br4923 VSIRSGAVQSMPGMMDTILNLGINDPVEQALAAASPSPIPQTFARDTRLR
: .
Mvan_1818|M.vanbaalenii_PYR-1 SSGILGNSREQ---FSMSICGRVVDELEAKPPRPFARKLV-NTVRLTSHA
Mflv_0493|M.gilvum_PYR-GCK SSGILGNSLEQ---FSLSVCGRVIDELEPGPPKPFVRKLI-NTVRLSTFA
Mb2073c|M.bovis_AF2122/97 MAATVPFAKPA---TIVSNSGFFGPSMASLPIFGAQRPPS-ESS-RARRW
Rv2047c|M.tuberculosis_H37Rv MAATVPFAKPA---TIVSNSGFFGPSMASLPIFGAQRPPS-ESS-RARRW
MMAR_3024|M.marinum_M MAETVPFAKPA---MIVSNSGFFGPSMGSLPIFGEERPPA-ESS-FVRRQ
MUL_2265|M.ulcerans_Agy99 MAETVPFAKPA---MIVSNSGFFGPSMGSLPIFGEERPPA-ESS-FVRRQ
TH_3290|M.thermoresistible__bu VSHAIPKSMREGSVAWLNSADRKAAASWPFSWREYVRMLA-RIQFMTQNG
MAV_5056|M.avium_104 FLCEMGDLIPG-----QSGEALSRDFFGFVPADFRSRPSARRLPFILARY
MSMEG_3934|M.smegmatis_MC2_155 ASGRVRVLLAP-----DDGDKLTDGEILVAPTTNPDWLPTIRRAAALVTE
MLBr_00955|M.leprae_Br4923 FIRTYRRIVDP---LNPPPANTYDQLRAAIESIFSSWNSPRAVAYRTHYG
Mvan_1818|M.vanbaalenii_PYR-1 LSAGPAIRRLADQIAGWPIPSHEDARLVLQQLE-------SGVQLYCDVT
Mflv_0493|M.gilvum_PYR-GCK LSSAPAIRRLPQTIAAFPPITSRDPAVVLRHLE-------AGVDIYREVT
Mb2073c|M.bovis_AF2122/97 LRTLRNIGVFGVNLVGLSAGSPRDTDAYVADVDRLERLAFDNLATHDDRR
Rv2047c|M.tuberculosis_H37Rv LRTLRNIGVFGVNLVGLSAGSPRDTDAYVADVDRLERLAFDNLATHDDRR
MMAR_3024|M.marinum_M LRTVRNIGVFGVNLVGLSAGSALDTNDFIADVDRLEQLAGGDVTTLDDRR
MUL_2265|M.ulcerans_Agy99 LCTVRNIGVFGVNLVGLSAGSALDTNDFIADVDRLEQLAGGDVTTLDDRR
TH_3290|M.thermoresistible__bu LYEWFKEADN-YDLEKVPERGRLDPEALKLWSDEALR---RLIKQYTDYA
MAV_5056|M.avium_104 PRTFAGIGRRIARLRSETDAWWRHEIAAVSRLD---------LRLAQRLA
MSMEG_3934|M.smegmatis_MC2_155 TGGMTCHAAIVARELGVPCVVGARSATVALAVG-----------SMVTVD
MLBr_00955|M.leprae_Br4923 LDDQSGTAVIVQAMVFGNQGAYSGAGTLFSRNP-----ITRESKLFGEWL
Mvan_1818|M.vanbaalenii_PYR-1 LTHVRSSSRAAVAANILESTLVRQAVKNGRSEEEGQAEAARLMAGASDVE
Mflv_0493|M.gilvum_PYR-GCK LIHVRSSSRSAVAANVLESHLVRRAAKRGASDTAGSAEAIRLMTGAG-VE
Mb2073c|M.bovis_AF2122/97 LLSLILLARDHVVHGWVLASGSFMLCAAFNVLLRGLCGRDTAPAAGPELV
Rv2047c|M.tuberculosis_H37Rv LLSLILLARDHVVHGWVLASGSFMLCAAFNVLLRGLCGRDTAPAAGPELV
MMAR_3024|M.marinum_M LLSLILLARDHVVHGWVLASGSFMLCAAFNVLLRAVSGRDTAPAAGPELV
MUL_2265|M.ulcerans_Agy99 LLSLILLARDHVVHGWVLASGSFMLCAAFNVLLRAVSGRDTAPAAGPELV
TH_3290|M.thermoresistible__bu ENKHYSQWTGWFIHAANAMTILGKMLASWYDGTNANIFTDLITGLPERTR
MAV_5056|M.avium_104 AEARDRFFTTLAAQAVISATVIQPVQEQLSTLCKAAGVDPAVLLRGASHE
MSMEG_3934|M.smegmatis_MC2_155 GTRGEVTTGRLPETVRTTTTPQEPAPHITGEATGTKVYVNLAMPDSAEAV
MLBr_00955|M.leprae_Br4923 PGGQGDDVVSGLVEVQPITSLRDEQPTVYDELVDTAGRLERLGSDVQEIE
Mvan_1818|M.vanbaalenii_PYR-1 SAMMLDQLQSVVRAIAA-DSGVATRFLAAAPDVAVVELQRADN--ASGEA
Mflv_0493|M.gilvum_PYR-GCK SALMVEELTAVVSMLRR-DGDAAARFLAAPAGEAVTRLRAAET--PSGAA
Mb2073c|M.bovis_AF2122/97 SARSVEAVQRLVAAARR-DPVVIR--LLAEPGERLDKLAVEAP--EFHSA
Rv2047c|M.tuberculosis_H37Rv SARSVEAVQRLVAAARR-DPVVIR--LLAEPGERLDKLAVEAP--EFHSA
MMAR_3024|M.marinum_M SARSVEAVQRLVAAARH-DEAVIR--LLSEPGDRLGKLAVAAP--HFYDA
MUL_2265|M.ulcerans_Agy99 SARSVEAVQRLVDAARH-DEAVIR--LLSEPGDRLGKLAVAAP--HFYDA
TH_3290|M.thermoresistible__bu TMQENIDLWQLASAIRS-NAAVRELFEKSSETEFFDRLADLPEGASVYAQ
MAV_5056|M.avium_104 ENAVLHDLWAASRGALE-VDEFVKRHGYHGPGEGELETRVWRE---DPGA
MSMEG_3934|M.smegmatis_MC2_155 AAQDVDGVGLLRAEFML-TEALAGRHPRDLITKGEQDTLVDAMAAAVTRI
MLBr_00955|M.leprae_Br4923 FTTEDSKLWLLQTRVAERSAQVAVRLALQLWQEGLIDDAEALRRVTPVHV
:
Mvan_1818|M.vanbaalenii_PYR-1 LRQFLLRHGHRGYRELCMRDPSWAQDAGGLGAMMQVMVRAASSDR-----
Mflv_0493|M.gilvum_PYR-GCK LRTFLDRHGHRGYRELCMRDPSWADDPDGLGAMMQVMLRGAAPEN-----
Mb2073c|M.bovis_AF2122/97 VLAELTLIGHRGPAEVEMAATSYADNPELLVRMVAKTLRAVP--------
Rv2047c|M.tuberculosis_H37Rv VLAELTLIGHRGPAEVEMAATSYADNPELLVRMVAKTLRAVP--------
MMAR_3024|M.marinum_M VRQELSLIGHRGPAEVEMMSTSYADNPELLVGMVAKTLSTSS--------
MUL_2265|M.ulcerans_Agy99 VRQELSLIGHRGPAEVEMMSTSYADNPELLVGMVAKTLSTSS--------
TH_3290|M.thermoresistible__bu YREFLDLHGHRGHADRDFYFPRRLDDPAIDYRLLKALLSGDGSFDPVAAE
MAV_5056|M.avium_104 VAGLVRRYSAR--SDAESPDADAAEHHRRRSEAERDLMSSLG--------
MSMEG_3934|M.smegmatis_MC2_155 GTAFAPRPVIYRAMDFRTNEFRGLAGGEQFEPVEHNPMIGYRG-------
MLBr_00955|M.leprae_Br4923 ETVLLPVLQPENHLSATLLAKGTPTCPGVISGKAYTEVDEALD-------
. :
Mvan_1818|M.vanbaalenii_PYR-1 ----------------QPAHSPTEAPTSPAIRFLARLAQGGARGREETKS
Mflv_0493|M.gilvum_PYR-GCK ----------------PAATAPSDPAQSRTLRVLARLAQAGARGREETKS
Mb2073c|M.bovis_AF2122/97 ------------------APQPPTPVIPLRAKPVALLAARQLRDREVRRD
Rv2047c|M.tuberculosis_H37Rv ------------------APQPPTPVIPLRAKPVALLAARQLRDREVRRD
MMAR_3024|M.marinum_M ------------------VPQPPQPSIPLQAKPIAVLAARQLRDREARRD
MUL_2265|M.ulcerans_Agy99 ------------------VPQPPQPSIPLQAKPIAVLAARQLRDREARRD
TH_3290|M.thermoresistible__bu KELQRRREAAVADVLDRLRNQPMGALRVAAFNTVYKYVVRFMLHRDNQRH
MAV_5056|M.avium_104 ------------------------PAARVRARLVLRLARNYIPLRGTGKV
MSMEG_3934|M.smegmatis_MC2_155 -----------------------CYRYIKEPDLFALELSALARAREHTPN
MLBr_00955|M.leprae_Br4923 ---------------------------------AAESAEQVILVRDHTRP
*
Mvan_1818|M.vanbaalenii_PYR-1 KMALMAHALKRGYRHLGEVLARSGRLPDADLVFFFDRSELPRVVGDDDIS
Mflv_0493|M.gilvum_PYR-GCK RMALMAHLLKRGYRHLGEVLHEAGRLPDADLVFFFDRRELPLVVSGDDVT
Mb2073c|M.bovis_AF2122/97 RMVRAIWVLRALLREYGRRLTEAGVFDTPDDVFYLLVDEIDALP-----A
Rv2047c|M.tuberculosis_H37Rv RMVRAIWVLRALLREYGRRLTEAGVFDTPDDVFYLLVDEIDALP-----A
MMAR_3024|M.marinum_M KMVRAIWVLRALLREHGRRLAEAGVLHASDDVFYLLVDELDALP-----A
MUL_2265|M.ulcerans_Agy99 KMVRAIWVLRALLREHGRRLAEAGVLHASDDVFYLLVDEVDALP-----A
TH_3290|M.thermoresistible__bu HLDRVTYAKKLAFTEVGRRVHERGLLPREDDFYFLTEDELFGLLHGTGNA
MAV_5056|M.avium_104 AYLQSLDVLRAAARRIGSLLVEQQRLTDPDDAFYLTIDELTGAPLADAAT
MSMEG_3934|M.smegmatis_MC2_155 IHLMIPFVRTRWELEECLALVDASPLRRHRNLHRWVMAEVPSVVH-----
MLBr_00955|M.leprae_Br4923 DDVLGMLASQGVVTEVGGAASHAAVVSR----------------------
. .
Mvan_1818|M.vanbaalenii_PYR-1 ELVQSAVK-RREALAYQDS---LEFEDVSVGR--PRPVVAPPVITSTADQ
Mflv_0493|M.gilvum_PYR-GCK ELVHRARQ-RREALPFQAA---LEFGDVSVGR--PTPIVR--AAVSGDGV
Mb2073c|M.bovis_AF2122/97 DVSGLVAR-RRAEQRRLAG---IVPPTVFSGS--WEPSPSSAAALAAGDT
Rv2047c|M.tuberculosis_H37Rv DVSGLVAR-RRAEQRRLAG---IVPPTVFSGS--WEPSPSSAAALAAGDT
MMAR_3024|M.marinum_M DVAELVAR-RRAEQRRLTA---VVPPTVFSGK--WEPSTASAAALTAGGT
MUL_2265|M.ulcerans_Agy99 DVAELVAR-RRAEQRRLTA---VVPPTVFSGK--WEPSTASAAALTAEGT
TH_3290|M.thermoresistible__bu RLCQAKVIGRRNAFEQYASGKFVPPEFMQNGREWVDPEAQQLQVADDGSG
MAV_5056|M.avium_104 DLRGTISE-RREIRAHYQS---LTLPSAWTGQ--PEPLAPSASAETSVRS
MSMEG_3934|M.smegmatis_MC2_155 ------------WLPEYVG---MGIDGVSIGS---NDLTQLMLGVDRDSE
MLBr_00955|M.leprae_Br4923 -----------------------ELSRVAVVG------CGQGTAVSLAGK
Mvan_1818|M.vanbaalenii_PYR-1 VVGRPASRGTVEGTVRVAKTIQDARDVQRGEILVAPVTDVGWTPYFTVIA
Mflv_0493|M.gilvum_PYR-GCK VAGRPAGHGSVEGVVRVARSVVEARDLQPGEILVAPVTDVGWTPYFAVIA
Mb2073c|M.bovis_AF2122/97 LRGVGVCGGRVRGRVRIVR-PETIDDLQPGEILVAEVTDVGYTAAFCYAA
Rv2047c|M.tuberculosis_H37Rv LRGVGVCGGRVRGRVRIVR-PETIDDLQPGEILVAEVTDVGYTAAFCYAA
MMAR_3024|M.marinum_M LRGVGVCGGRVRGRVRIVR-PETIDELEPGEILVAEVTDVGYTAAFCYAA
MUL_2265|M.ulcerans_Agy99 LRGVGVCGGRVRGRVRIVR-PETIDELEPGEILVAEVTDVGYTAAFCYAA
TH_3290|M.thermoresistible__bu IQGFGTSPGTYTGRARVITSLDDIGRVEQGDVLITNSTDPAWTPVFLVIG
MAV_5056|M.avium_104 LRGIGACAGVAEGRAVVVTDPTET-EIADGDILIAQTTDPSWVSLMFLSA
MSMEG_3934|M.smegmatis_MC2_155 TCAELFDESDAAVLDAISRIISTANRLGITSSLCGQAPSTRPEFAEHLVR
MLBr_00955|M.leprae_Br4923 QITVDGDKGEVRQGNLTLSAWSENETPELRELADIARRISPLRVHMTEDH
. .
Mvan_1818|M.vanbaalenii_PYR-1 ALITDIGSSVSHGAVVAREYGLPCVVNTLVGTQVLRTGDRVRVDGDRGVV
Mflv_0493|M.gilvum_PYR-GCK ALVTDIGSSVSHGAVVAREYGLPCVVNTLVGTQVLRTGDRVRVDGDRGLV
Mb2073c|M.bovis_AF2122/97 AVVTELGGPMSHAAVVAREFGFPCVVDAQGATRFLPPGALVEVDGATGEI
Rv2047c|M.tuberculosis_H37Rv AVVTELGGPMSHAAVVAREFGFPCVVDAQGATRFLPPGALVEVDGATGEI
MMAR_3024|M.marinum_M AVVTELGGPMSHAAVVAREFGFPCVVDAQGATRFLPPGALIEVDGTTGEI
MUL_2265|M.ulcerans_Agy99 AVVTELGGPMSHAAVVAREFGFPCVVDAQGATRFLPPGALIEVDGTTGEI
TH_3290|M.thermoresistible__bu GLVLETGGLLAHGACLSREYNLPAVTAPAATTRIP-DGATITVDGVAGTV
MAV_5056|M.avium_104 ALVVDIGGLMSHAAVMARELGIPCVMNTGTGTTALRTGDTIRVDGAAGTV
MSMEG_3934|M.smegmatis_MC2_155 MGITSVSVNPDAAGAARRAVAAAERRLLLDSVRHPRHAPTASPRNPL---
MLBr_00955|M.leprae_Br4923 TRLDDSSDTAVRLAINTGHADVVSATPLIVMMTTLRLQDSKDSSAKS---
: . . .
Mvan_1818|M.vanbaalenii_PYR-1 TRLG------------------
Mflv_0493|M.gilvum_PYR-GCK TVLDSP----------------
Mb2073c|M.bovis_AF2122/97 HVVELASEDGPALPGSDLSR--
Rv2047c|M.tuberculosis_H37Rv HVVELASEDGPALPGSDLSR--
MMAR_3024|M.marinum_M QVLELAAEGDSSVTQSDPADLA
MUL_2265|M.ulcerans_Agy99 QVLELAAEGDSSVTQSDPADLA
TH_3290|M.thermoresistible__bu IVHQEATVQ-------------
MAV_5056|M.avium_104 EILSRNIQQSSIPERTH-----
MSMEG_3934|M.smegmatis_MC2_155 ----------------------
MLBr_00955|M.leprae_Br4923 ----------------------