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M. smegmatis MC2 155 MSMEG_3934 (-)

annotation: phosphoenolpyruvate synthase
coordinates: 4001317 - 4003635
length: 772

VDIMSDRYVRTLDILTIADAEEAGGKGANLGELVAADLPVPHGFVVMRSAYLDSVRMGGVEAELAALHTE
ALTHAADTARLSELCRRMQSLVNKAGLSPSVRDATLAAYRALGTDVVVAVRSSATGEDGRDASFAGMNRT
ITNVMGEVALLDAVTQCWMSLFSPRVITYRASRGFTAAPAMAVVVQQMLSADRAGVAFTSDPSTGDADHI
VIEAAFGQGEVVVSGKVEPDTYVIDKRTLEVRDVRIGFKAIKIVRGDDGADSMVQLERSQAEARVLDDDA
LRKIATLAVATETHNGCPQDIEWVIADGAVWLVQARPITTLGSAGSTAGDEPSVLIRGLPAAPGVASGRV
RVLLAPDDGDKLTDGEILVAPTTNPDWLPTIRRAAALVTETGGMTCHAAIVARELGVPCVVGARSATVAL
AVGSMVTVDGTRGEVTTGRLPETVRTTTTPQEPAPHITGEATGTKVYVNLAMPDSAEAVAAQDVDGVGLL
RAEFMLTEALAGRHPRDLITKGEQDTLVDAMAAAVTRIGTAFAPRPVIYRAMDFRTNEFRGLAGGEQFEP
VEHNPMIGYRGCYRYIKEPDLFALELSALARAREHTPNIHLMIPFVRTRWELEECLALVDASPLRRHRNL
HRWVMAEVPSVVHWLPEYVGMGIDGVSIGSNDLTQLMLGVDRDSETCAELFDESDAAVLDAISRIISTAN
RLGITSSLCGQAPSTRPEFAEHLVRMGITSVSVNPDAAGAARRAVAAAERRLLLDSVRHPRHAPTASPRN
PL
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_3934--100% (772)phosphoenolpyruvate synthase
M. smegmatis MC2 155MSMEG_0088ptsI1e-3031.39% (395) phosphoenolpyruvate-protein phosphotransferase
M. smegmatis MC2 155MSMEG_2121-2e-2729.22% (421) multiphosphoryl transfer protein (MTP)

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1158cppdK9e-2127.53% (454) pyruvate phosphate dikinase
M. gilvum PYR-GCKMflv_4990-0.070.84% (751) phosphoenolpyruvate synthase
M. tuberculosis H37RvRv1127cppdK2e-2027.15% (453) pyruvate phosphate dikinase
M. leprae Br4923MLBr_00955ppdK3e-1827.59% (319) pyruvate phosphate dikinase
M. abscessus ATCC 19977-----
M. marinum MMMAR_3410-1e-12338.86% (808) pyruvate dikinase
M. avium 104MAV_5059-3e-2727.24% (492) pyruvate phosphate dikinase
M. thermoresistible (build 8)TH_1154-0.071.54% (773) phosphoenolpyruvate synthase
M. ulcerans Agy99MUL_0141ppdK1e-2129.77% (487) pyruvate phosphate dikinase
M. vanbaalenii PYR-1Mvan_4106-1e-12137.79% (807) phosphoenolpyruvate synthase

CLUSTAL 2.0.9 multiple sequence alignment


Mb1158c|M.bovis_AF2122/97           ---------------MTR--------------------------------
Rv1127c|M.tuberculosis_H37Rv        ---------------MTR--------------------------------
MUL_0141|M.ulcerans_Agy99           MP------KTTRGCTTTR--------------------------------
MLBr_00955|M.leprae_Br4923          MPGQSHKEPHRRATSTPRSLKQATSELRWALSLAAPESPAFMRHLLGNAH
MAV_5059|M.avium_104                --------------------------------------------------
Mflv_4990|M.gilvum_PYR-GCK          --------------------------------------------------
TH_1154|M.thermoresistible__bu      --------------------------------------------------
MSMEG_3934|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_3410|M.marinum_M               --------------------------------------------------
Mvan_4106|M.vanbaalenii_PYR-1       --------------------------------------------------
                                                                                      

Mb1158c|M.bovis_AF2122/97           ----ITRANGCPDGTLENAVVALDGGANYPREILGNKGHGIDMMRR----
Rv1127c|M.tuberculosis_H37Rv        ----ITRANGCPDGTLENAVVALDGGANYPREILGNKGHGIDMMRR----
MUL_0141|M.ulcerans_Agy99           ----FSRAGGIP--FTGPAVVLLDGRAHQPREVLGNKGHGIDSMRR----
MLBr_00955|M.leprae_Br4923          DKVDITTSSEHVAAFTEHAIVLLNGNAHQTRELLGGKGYNINAMRR----
MAV_5059|M.avium_104                --------MSAPTDQATERVQALVGDGQLTRAQAGGKAWSIQHMLS----
Mflv_4990|M.gilvum_PYR-GCK          ----------MESGTRNTHVCDISALSIGDAEEAGGKGANMGELVA----
TH_1154|M.thermoresistible__bu      ----------MDH-VADRFVRDIAELRITDAEEAGGKGANMGEMVA----
MSMEG_3934|M.smegmatis_MC2_155      ----------MDI-MSDRYVRTLDILTIADAEEAGGKGANLGELVA----
MMAR_3410|M.marinum_M               ----------MSS---FSYVRFFEEFGIEDVPLVGGKNASLGEMFQKLSQ
Mvan_4106|M.vanbaalenii_PYR-1       ----------MGT---SEYVRFFEDFGIEDVPLVGGKNASLGEMIQNLSA
                                                       :  :           *.*  .:  :      

Mb1158c|M.bovis_AF2122/97           HHLPVPPAFCITTEVGVRYLAAPESTIAAIWDDVLDRMSWLETETSCTFG
Rv1127c|M.tuberculosis_H37Rv        HHLPVPPAFCITTEVGVRYLAAPGSTIAAIWDDVLDRMSWLETETSCTFG
MUL_0141|M.ulcerans_Agy99           NNLPVPPAFCITSEVGVRYLADPAPTLDAIWDDVVDRIRWLEAETGRTFG
MLBr_00955|M.leprae_Br4923          HQLAVPPAFCITTEVGVRYLAAPTPTMEAIWNDVLDQMRWLEAETSRTFG
MAV_5059|M.avium_104                LNIPVPPGFVLTTDVCREYHDRGRVLPAGVTRDIARAMENLESRSGRRFG
Mflv_4990|M.gilvum_PYR-GCK          AKLPVPPGFVLLRDCYRDSMRAGG-VDAELASLHREALDDVADTARLGEL
TH_1154|M.thermoresistible__bu      AALPVPPGFVLLRDCYLESMQAGG-VRSELAALHDEALAKVPDTEQLPAL
MSMEG_3934|M.smegmatis_MC2_155      ADLPVPHGFVVMRSAYLDSVRMGG-VEAELAALHTEALTHAADTARLSEL
MMAR_3410|M.marinum_M               QGVRVPHGFATTADAYKHMLDRAG-AWDALHAELDD--LDADDVTALARK
Mvan_4106|M.vanbaalenii_PYR-1       QGVRVPHGFAITAAAYRHMLDEAG-AWERLHAELDD--LDPDDVAALARK
                                      : ** .*                    :                    

Mb1158c|M.bovis_AF2122/97           RGPNPLLVSVRSGATQSMPGMMDTILDVGMTDAVERVLARPG----AADF
Rv1127c|M.tuberculosis_H37Rv        RGPNPLLVSVRSGATQSMPGMMDTILDVGMTDAVERVLARPG----AADF
MUL_0141|M.ulcerans_Agy99           SGPHPLLVSVRSGANQSMPGMMDTILDLGMNDTVEQALASPG----TGDF
MLBr_00955|M.leprae_Br4923          WGPRPLLVSIRSGAVQSMPGMMDTILNLGINDPVEQALAAASPSPIPQTF
MAV_5059|M.avium_104                HVDHPLLVSVRSGAAISMPGMMDTILNLGMNSSIEEALAAETG---DARY
Mflv_4990|M.gilvum_PYR-GCK          CERMQGLVRKAGVDDATAADMLAAYHAM----GPGAVVAVRS----SATG
TH_1154|M.thermoresistible__bu      CERLQSLVRKAGMADEVRKSVLAAYRRL----GPDAVVAVRS----SATG
MSMEG_3934|M.smegmatis_MC2_155      CRRMQSLVNKAGLSPSVRDATLAAYRAL----GTDVVVAVRS----SATG
MMAR_3410|M.marinum_M               GKRAREIVYGAGLPEDLASEIVAAYRIMQEEYGEDVSLAVRS----SATA
Mvan_4106|M.vanbaalenii_PYR-1       AKRAREIVYGAGLPDDLAAEILDGYRALQREYGEEVSLAVRS----SATA
                                          :*   .         :     :         :*           

Mb1158c|M.bovis_AF2122/97           AHDTRRRFTSMYRRIVGSAGPITDDPYAQLRASIEAVFASWNSPRAVAYR
Rv1127c|M.tuberculosis_H37Rv        AHDTRRRFTSMYRRIVGSAGPITDDPYAQLRASIEAVFASWNSPRAVAYR
MUL_0141|M.ulcerans_Agy99           ARDTRRRFTRMYRRIVAGSDPP-DDPYEQLRAGIGAVFASWNSPRAIAYR
MLBr_00955|M.leprae_Br4923          ARDTRLRFIRTYRRIVDPLNPPPANTYDQLRAAIESIFSSWNSPRAVAYR
MAV_5059|M.avium_104                AADTRHRFTEQFTRVVG-VEPP-ENHWEQLDLAIRAVLESWNSKRALAYR
Mflv_4990|M.gilvum_PYR-GCK          EDGADASFAGMNATLTNITGDD------GLVTAVTRCWMSLFSPRVITYR
TH_1154|M.thermoresistible__bu      EDGRDASFAGMNATMTNVAGED------ALLEAVVRCWMSLFSPRVITYR
MSMEG_3934|M.smegmatis_MC2_155      EDGRDASFAGMNRTITNVMGEV------ALLDAVTQCWMSLFSPRVITYR
MMAR_3410|M.marinum_M               EDLPTASFAGQQETFLNIKGEE------SLLDACRRCFASLFTDRAIHYR
Mvan_4106|M.vanbaalenii_PYR-1       EDLPTASFAGQQDSYLNIKGEE------SLLDTCRRCFASLFTDRAIHYR
                                           *                     *         *  : *.: **

Mb1158c|M.bovis_AF2122/97           DHHGLDD-QGGTAVVVQAMVFGNLTANSGAGVLSSRNPITGANEPFGEWL
Rv1127c|M.tuberculosis_H37Rv        DHHGLDD-QGGTAVVVQAMVFGNLTANSGAGVLSSRNPITGANEPFGEWL
MUL_0141|M.ulcerans_Agy99           NHYSLDD-QGGTAVVVQAMVFGNRSADSGAGVLSSRNPITGASEPFGEWL
MLBr_00955|M.leprae_Br4923          THYGLDD-QSGTAVIVQAMVFGNQGAYSGAGTLFSRNPITRESKLFGEWL
MAV_5059|M.avium_104                RSHGIPD-DGGTAVTVQAMVFGNLDDRSGTGVLFSRDPLSGAAQPYGEWL
Mflv_4990|M.gilvum_PYR-GCK          ASRGFLG-TPAMAVVVQKMIDSEKS-----GVAFTADPSTGARDRVVIEA
TH_1154|M.thermoresistible__bu      ASRGFTD-EPAMAVVVQQMIASEKS-----GVAFTADPSSGAQDRVVVEA
MSMEG_3934|M.smegmatis_MC2_155      ASRGFTA-APAMAVVVQQMLSADRA-----GVAFTSDPSTGDADHIVIEA
MMAR_3410|M.marinum_M               VDQGFDHFKVALSIGIMKMVRSDLAS---SGVMFTLDTESGFNDVVFVTG
Mvan_4106|M.vanbaalenii_PYR-1       IDQGFDHFKVSLSIGVMKMVRSDIAS---SGVMFSIDTESGFRDAVFITG
                                       .:     . :: :  *: .:       *.  : :. :   .      

Mb1158c|M.bovis_AF2122/97           PGGQGDDVVSGLVAVAPITALRDQ-------QPAVYDQLMAAARSLERMA
Rv1127c|M.tuberculosis_H37Rv        PGGQGDDVVSGLVAVAPITALRDQ-------QPAVYDQLMAAARSLERMA
MUL_0141|M.ulcerans_Agy99           PGGQGDDVVSGLLKVEPITALRDR-------LPKIYLELLDAARGLERLA
MLBr_00955|M.leprae_Br4923          PGGQGDDVVSGLVEVQPITSLRDE-------QPTVYDELVDTAGRLERLG
MAV_5059|M.avium_104                PRGQGEDVVSGRKDALHLDHLAAT-------MPSVHRDLLAAAATLERHG
Mflv_4990|M.gilvum_PYR-GCK          AFGLGEVVVSGSVEPDTYVVSKET-----MEPIDVRLGNKTFKIVRGEDG
TH_1154|M.thermoresistible__bu      AWGLGEVVVAGQVEPDTYVVAKED-----LGVLDVRIGHKPFKIVRGPDG
MSMEG_3934|M.smegmatis_MC2_155      AFGQGEVVVSGKVEPDTYVIDKRT-----LEVRDVRIGFKAIKIVRGDDG
MMAR_3410|M.marinum_M               AYGLGENVVQGAVDPDEFYVHKPTYQAGHRAVLRRLIGDKAVKMVFVEGG
Mvan_4106|M.vanbaalenii_PYR-1       AYGLGENVVQGAVDPDEFYVHKPTYLAGHRAVLRRLLGDKAVKMILVEGE
                                    . * *: ** *                                       

Mb1158c|M.bovis_AF2122/97           GDVQEIEFTVEDSQLWLLQTRGAERSAQAAVRLALQLHHEGLIDDTETLR
Rv1127c|M.tuberculosis_H37Rv        GDVQEIEFTVEDSQLWLLQTRGAERSAQAAVRLALQLHHEGLIDDTETLR
MUL_0141|M.ulcerans_Agy99           AEVQEVEFTVESGKLWLLQTRSAERSAQAAVRLALQLRGAGLIDDGETLR
MLBr_00955|M.leprae_Br4923          SDVQEIEFTTEDSKLWLLQTRVAERSAQVAVRLALQLWQEGLIDDAEALR
MAV_5059|M.avium_104                RDMQDIEFTVQSGKLWLLQSRAAKRSPQAALRCAVQLQREGVISTKEALD
Mflv_4990|M.gilvum_PYR-GCK          SDTV---VQLDDATAASRVLTDEELHSVAELAVATERHNGCPQDTEWAI-
TH_1154|M.thermoresistible__bu      NDQR---VDLPDDQAHARVLDDRELRRIAELAIATEQHNGCPQDTEWAID
MSMEG_3934|M.smegmatis_MC2_155      ADSM---VQLERSQAEARVLDDDALRKIATLAVATETHNGCPQDIEWVI-
MMAR_3410|M.marinum_M               TKQTTRNIPTPKADRAHFCITDEDVLELAGYALAIEQHYGRPMDIEWAKD
Mvan_4106|M.vanbaalenii_PYR-1       TKNTTRNIPTPKADRARFCLTDDDALELAGYACAIEAHYGRPMDMEWAKD
                                     .     .                    .    * :       .   .  

Mb1158c|M.bovis_AF2122/97           RVTPTHIETLLRPSLQPETRLAAP--------------LLAKGLPACPGV
Rv1127c|M.tuberculosis_H37Rv        RVTPTHIETLLRPSLQTETRLAAP--------------LLAKGLPACPGV
MUL_0141|M.ulcerans_Agy99           RITPTHVETLLLPTLHPDERLAAS--------------LLAKGLPACPGV
MLBr_00955|M.leprae_Br4923          RVTPVHVETVLLPVLQPENHLSAT--------------LLAKGTPTCPGV
MAV_5059|M.avium_104                RLTAEHVRALQRPTLDPAAVAASP--------------PVASGKPASPGI
Mflv_4990|M.gilvum_PYR-GCK          -ADGAAYLVQARPITTLGHTTPPARTEHV---------VLARGLAAAPGI
TH_1154|M.thermoresistible__bu      -AAGEAFLVQARPITTLRHAAAPTSEEHV---------TLARGLAAAPGL
MSMEG_3934|M.smegmatis_MC2_155      -ADGAVWLVQARPITTLGSAGSTAGDEPS---------VLIRGLPAAPGV
MMAR_3410|M.marinum_M               GLDGKLYIVQARPETAASQRSMTTVETYVLEGSGEQREILTEGRSVGEKV
Mvan_4106|M.vanbaalenii_PYR-1       GLDGKLYIVQARPETVASQHSVTALESYVLDGHG---DILTEGRSVGEKI
                                            .   *         ..               :  * ..   :

Mb1158c|M.bovis_AF2122/97           VSGTAYTEVDEALDAADRGEPVILVRDHTRPEDVMGMLAAQGIVTEVGGA
Rv1127c|M.tuberculosis_H37Rv        VSGTAYTEVDEALDAADRGEPVILVRDHTRPEDVMGMLAAQGIVTEVGGA
MUL_0141|M.ulcerans_Agy99           AAGLAYTDVDEALDAADRGEQVILVRDHTRPEDVSGMLAAQGIVTEIGGA
MLBr_00955|M.leprae_Br4923          ISGKAYTEVDEALDAAESAEQVILVRDHTRPDDVLGMLASQGVVTEVGGA
MAV_5059|M.avium_104                ATGLVVIDADEAEDLADKGRAVILARPTTDPDDVAAMSASVAVVTELGGS
Mflv_4990|M.gilvum_PYR-GCK          ASG-KVRVLQTPDEGHRLQEGEILVAQMTNPDWLPTIRRAAALVTDTGGM
TH_1154|M.thermoresistible__bu      ASG-RVRVLRSPEEGSQLQDGEILVAPMTNPDWLPTIRRAAALVTDTGGM
MSMEG_3934|M.smegmatis_MC2_155      ASG-RVRVLLAPDDGDKLTDGEILVAPTTNPDWLPTIRRAAALVTETGGM
MMAR_3410|M.marinum_M               ASG-VVKRIDDLERLSDFKPGQVLVADTTTPDWEPVMKIAAAIVTNRGGR
Mvan_4106|M.vanbaalenii_PYR-1       ASG-AVRRIEHLAQLSEFKPGEVLVADTTTPDWEPVMKTAAAIVTNRGGR
                                     :*                   :*.   * *:    :  : .:**: ** 

Mb1158c|M.bovis_AF2122/97           ASHAAVVSRELGRVAVVGCGPGVAAALAGKEITVD---GYEGEVRQGVLA
Rv1127c|M.tuberculosis_H37Rv        ASHAAVVSRELGRVAVVGCGPGVAAALAGKEITVD---GYEGEVRQGVLA
MUL_0141|M.ulcerans_Agy99           ASHAAVVSRELGRVAVVGCGDGVAASLAGKRITVD---GYTGEVREGILA
MLBr_00955|M.leprae_Br4923          ASHAAVVSRELSRVAVVGCGQGTAVSLAGKQITVD---GDKGEVRQGNLT
MAV_5059|M.avium_104                TSHAAVVCREMAVPCVVGCGMDSVTALAGRVVTVD---ADTGTVHLGELP
Mflv_4990|M.gilvum_PYR-GCK          TCHAAIVARELGVPCIVGTRTGTRDLHDGTTVTV---DGARGEVASG-VT
TH_1154|M.thermoresistible__bu      TCHAAIVARELGVPCVVGTRTATRDLHNGTTVTV---DGTHGRVVSGRMA
MSMEG_3934|M.smegmatis_MC2_155      TCHAAIVARELGVPCVVGARSATVALAVGSMVTV---DGTRGEVTTGRLP
MMAR_3410|M.marinum_M               TCHAAIIARELGIPAVVGAGDATTNVPDGQLVTVSCVEGDTGRVYRGEVG
Mvan_4106|M.vanbaalenii_PYR-1       TCHASIIARELGIPAVVGTGDGTTSVPNGAVVTVSCAEGDTGRVYDGAVG
                                    :.**:::.**:.  .:**          *  :**    .  * *  * : 

Mb1158c|M.bovis_AF2122/97           LSAWSESDTP----------------------------------------
Rv1127c|M.tuberculosis_H37Rv        LSAWSESDTP----------------------------------------
MUL_0141|M.ulcerans_Agy99           PSAWSEDDTP----------------------------------------
MLBr_00955|M.leprae_Br4923          LSAWSENETP----------------------------------------
MAV_5059|M.avium_104                VRPLLEADDE----------------------------------------
Mflv_4990|M.gilvum_PYR-GCK          EPAPQMTVSPRSAP--APVTAEVTGTRVYVNLAMPESAETVAAQPVDGVG
TH_1154|M.thermoresistible__bu      SPAAAVTLAEPAARPALAAPAEVTATKIYVNLAMPDSAEEVAARGADGVG
MSMEG_3934|M.smegmatis_MC2_155      ETVRTTTTPQEPAP---HITGEATGTKVYVNLAMPDSAEAVAAQDVDGVG
MMAR_3410|M.marinum_M               FHVDRTEVADLARP----------RTEVMVNLGNPDLAFKTSFLPNDGVG
Mvan_4106|M.vanbaalenii_PYR-1       FHVDRTEVGDIARP----------RTEIMLNLGNPDLAFKTSFLPNDGVG
                                                                                      

Mb1158c|M.bovis_AF2122/97           --------------------------------------------------
Rv1127c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_0141|M.ulcerans_Agy99           --------------------------------------------------
MLBr_00955|M.leprae_Br4923          --------------------------------------------------
MAV_5059|M.avium_104                --------------------------------------------------
Mflv_4990|M.gilvum_PYR-GCK          LLRAEFMLTEALGGR-----HPR-----------DLIARGEQNM---LVE
TH_1154|M.thermoresistible__bu      LLRAEFMLTEALGGR-----HPR-----------DLIARGEQND---LVQ
MSMEG_3934|M.smegmatis_MC2_155      LLRAEFMLTEALAGR-----HPR-----------DLITKGEQDT---LVD
MMAR_3410|M.marinum_M               LARMEFIVGEYIKVHPLALLHPDKVDDPEARRTIERLTRGYSDGAEFFVQ
Mvan_4106|M.vanbaalenii_PYR-1       LARMEFIISEYIKVHPLALLHPERVADSEASRTIARLTQGYADGSEFFVE
                                                                                      

Mb1158c|M.bovis_AF2122/97           --------------------------------------------------
Rv1127c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_0141|M.ulcerans_Agy99           --------------------------------------------------
MLBr_00955|M.leprae_Br4923          --------------------------------------------------
MAV_5059|M.avium_104                --------------------------------------------------
Mflv_4990|M.gilvum_PYR-GCK          KMVDSVGRIAAAFSPRPVVYRATDFRSNEFRGLTGGAEYEPVEHNPMIGF
TH_1154|M.thermoresistible__bu      GMVNAVGRIAAAFAPRPVVYRATDFRTNEFRGLAGGDRYEPEEHNPMIGY
MSMEG_3934|M.smegmatis_MC2_155      AMAAAVTRIGTAFAPRPVIYRAMDFRTNEFRGLAGGEQFEPVEHNPMIGY
MMAR_3410|M.marinum_M               RLSEGIGTIAAAFWPKPVVVRMSDFKSNEYASLIGGSGFEPTESNPMIGF
Mvan_4106|M.vanbaalenii_PYR-1       RLSEGIGTIAAAFWPKPVVVRMSDFKTNEYASLVGGQSFEPLESNPMLGF
                                                                                      

Mb1158c|M.bovis_AF2122/97           -----------------ELRELADIAQRISS-------------------
Rv1127c|M.tuberculosis_H37Rv        -----------------ELRELADIAQRISS-------------------
MUL_0141|M.ulcerans_Agy99           -----------------ELRDLTTIALKISPLRAHASGDYPKLDDPSEAG
MLBr_00955|M.leprae_Br4923          -----------------ELRELADIARRISPLRVHMTEDHTRLDDSSDTA
MAV_5059|M.avium_104                -----------------DLRTIERWLR----------DDLENYDPSYDVV
Mflv_4990|M.gilvum_PYR-GCK          RGCYRYVK--EPELFALELEALARVRERS--PNVALMIPFVRTRWELEEC
TH_1154|M.thermoresistible__bu      RGCYRYIK--EPDVFALELQALARVREEN--PNVALMIPFVRTRWELEEC
MSMEG_3934|M.smegmatis_MC2_155      RGCYRYIK--EPDLFALELSALARAREHT--PNIHLMIPFVRTRWELEEC
MMAR_3410|M.marinum_M               RGASRYAHPAYAEGFALECRAMQRVRDQMGLTNVVIMLPFVRRVAEADLV
Mvan_4106|M.vanbaalenii_PYR-1       RGASRYAHPAYAEGFALECRAMRRVRDEMGLTNVIIMLPFVRRVAEADLV
                                                     :   :                            

Mb1158c|M.bovis_AF2122/97           --------------------------------------------------
Rv1127c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_0141|M.ulcerans_Agy99           VLTAMAAGYTDVVSDAPLITMLNALRVQDGL-------------------
MLBr_00955|M.leprae_Br4923          VRLAINTGHADVVSATPLIVMMTTLRLQDSKDSSAKS-------------
MAV_5059|M.avium_104                ALIERRQQRGATR-------------------------------------
Mflv_4990|M.gilvum_PYR-GCK          LSLVDASPLGR-QRGLHRWVMAEVPSVVHWLPEYIGMGIDGVSIGSNDLT
TH_1154|M.thermoresistible__bu      LELVDASPLGR-QRGLRRWVMAEVPSVVHWLPEYVGMGIDGVSIGSNDLT
MSMEG_3934|M.smegmatis_MC2_155      LALVDASPLRR-HRNLHRWVMAEVPSVVHWLPEYVGMGIDGVSIGSNDLT
MMAR_3410|M.marinum_M               LETMAEHGLRRGENGLKVYAMCEIPNNVILIDQFAKR-FDGFSIGSNDLT
Mvan_4106|M.vanbaalenii_PYR-1       LQTMADLGLKRGENGLKVYAMCEIPNNVILIDQFAKR-FDGFSIGSNDLT
                                                                                      

Mb1158c|M.bovis_AF2122/97           --------------------------------------------------
Rv1127c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_0141|M.ulcerans_Agy99           --------------------------------------------------
MLBr_00955|M.leprae_Br4923          --------------------------------------------------
MAV_5059|M.avium_104                --------------------------------------------------
Mflv_4990|M.gilvum_PYR-GCK          QLLLGVDRDSDVCAELFDESDPAVLHAIRRIVDTANKFGITSSLCGQAPS
TH_1154|M.thermoresistible__bu      QLMLGVDRDSDICAELFDESDAAVLDAIGRIVGTARRLGITSSLCGQAPS
MSMEG_3934|M.smegmatis_MC2_155      QLMLGVDRDSETCAELFDESDAAVLDAISRIISTANRLGITSSLCGQAPS
MMAR_3410|M.marinum_M               QLTLGVDRDSEIVAFDYDERDDGVKEMIRLAVEGCRRNGIHSGLCGQAPS
Mvan_4106|M.vanbaalenii_PYR-1       QLTLGVDRDSEVVAFDYDERDEGVKEMIRLAVEGCRRNGIHSGLCGQAPS
                                                                                      

Mb1158c|M.bovis_AF2122/97           --------------------------------------------------
Rv1127c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_0141|M.ulcerans_Agy99           --------------------------------------------------
MLBr_00955|M.leprae_Br4923          --------------------------------------------------
MAV_5059|M.avium_104                --------------------------------------------------
Mflv_4990|M.gilvum_PYR-GCK          TNPAFAEHLVRLGITSVSVNPDAVDATRRVIAAAERRIMLAAARSLPEDQ
TH_1154|M.thermoresistible__bu      TDPAFAEHLVRMGITSVSVNPDALESARRTVAAAERRILLESARNVQGDA
MSMEG_3934|M.smegmatis_MC2_155      TRPEFAEHLVRMGITSVSVNPDAAGAARRAVAAAERRLLLDSVRHPRHAP
MMAR_3410|M.marinum_M               DYPDMAEFLVRAGIDSVSLNPDVVVKTTRQILDLEQQVVPLQ--------
Mvan_4106|M.vanbaalenii_PYR-1       DYPDMAEFLVRIGIDSMSLNPDTVVKTTRQVLELERQLASAR--------
                                                                                      

Mb1158c|M.bovis_AF2122/97           --------
Rv1127c|M.tuberculosis_H37Rv        --------
MUL_0141|M.ulcerans_Agy99           --------
MLBr_00955|M.leprae_Br4923          --------
MAV_5059|M.avium_104                --------
Mflv_4990|M.gilvum_PYR-GCK          --------
TH_1154|M.thermoresistible__bu      PADAR---
MSMEG_3934|M.smegmatis_MC2_155      TASPRNPL
MMAR_3410|M.marinum_M               --------
Mvan_4106|M.vanbaalenii_PYR-1       --------