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M. thermoresistible (build 8) TH_4230 (-)

annotation: putative phosphoenolpyruvate synthase
coordinates: 3021977 - 3024700
length: 908

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4230--100% (908)putative phosphoenolpyruvate synthase
M. thermoresistible (build 8)TH_3290-0.050.28% (889) PUTATIVE putative phosphoenolpyruvate synthase
M. thermoresistible (build 8)TH_4555-0.043.04% (913) PUTATIVE putative phosphoenolpyruvate synthase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2073c-1e-2229.28% (345) hypothetical protein Mb2073c
M. gilvum PYR-GCKMflv_4990-4e-5239.54% (306) phosphoenolpyruvate synthase
M. tuberculosis H37RvRv2047c-1e-2229.28% (345) hypothetical protein Rv2047c
M. leprae Br4923MLBr_00955ppdK7e-0623.69% (249) pyruvate phosphate dikinase
M. abscessus ATCC 19977-----
M. marinum MMMAR_3410-2e-4235.82% (335) pyruvate dikinase
M. avium 104MAV_5062-4e-2627.39% (314) pyruvate, water dikinase
M. smegmatis MC2 155MSMEG_3934-8e-5439.87% (301) phosphoenolpyruvate synthase
M. ulcerans Agy99MUL_2265-9e-2330.82% (331) hypothetical protein MUL_2265
M. vanbaalenii PYR-1Mvan_2632-8e-4938.75% (320) pyruvate, water dikinase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4990|M.gilvum_PYR-GCK          ---MESGTRNTHVCDISALSIGDAEEAGGKG-------ANMGELVAAK--
MSMEG_3934|M.smegmatis_MC2_155      ---MDIMS-DRYVRTLDILTIADAEEAGGKG-------ANLGELVAAD--
MMAR_3410|M.marinum_M               ---MSSFS---YVRFFEEFGIEDVPLVGGKN-------ASLGEMFQKLS-
Mb2073c|M.bovis_AF2122/97           MRIAVTGASGVLGRGLTARLLSQGHEVVGIARHRPDSWPSSADFIAADIR
Rv2047c|M.tuberculosis_H37Rv        MRIAVTGASGVLGRGLTARLLSQGHEVVGIARHRPDSWPSSADFIAADIR
MUL_2265|M.ulcerans_Agy99           MRVAVTGAGGVLGRGLASRLLSQGHEVVGMSRRRPDSWPSQADFVAGDIR
MAV_5062|M.avium_104                --------------------------------------------------
Mvan_2632|M.vanbaalenii_PYR-1       -------MTGTMIHWLTDAGAADPSRSGGKG-------AKLALLVRAG--
TH_4230|M.thermoresistible__bu      ---------MSYIVEFSEPAAVQRAVAGGKG-------AHLASLTTAG--
MLBr_00955|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_4990|M.gilvum_PYR-GCK          -----LPVPPGFVLLRDCYRDSMR--------AGGVDAELASLHREALDD
MSMEG_3934|M.smegmatis_MC2_155      -----LPVPHGFVVMRSAYLDSVR--------MGGVEAELAALHTEALTH
MMAR_3410|M.marinum_M               --QQGVRVPHGFATTADAYKHMLDR-------AGAWDALHAELDDLDADD
Mb2073c|M.bovis_AF2122/97           DATAVESAMTGADVVAHCAWVRGR------NDHINIDGTANVLKAMAETG
Rv2047c|M.tuberculosis_H37Rv        DATAVESAMTGADVVAHCAWVRGR------NDHINIDGTANVLKAMAETG
MUL_2265|M.ulcerans_Agy99           DAAAVRRAITGADVVAHCAWARNPGPDGRISQQINIDGTRNVLDAMAACG
MAV_5062|M.avium_104                --------------------------------------------------
Mvan_2632|M.vanbaalenii_PYR-1       -----LPVPAGFVVLTEAYRRFVSDHG----LDGLIRQQLGAINTGPDGD
TH_4230|M.thermoresistible__bu      -----FTVPPGFVVTVDAFDAAVTRN-----IGADVEKILAGTDFADADA
MLBr_00955|M.leprae_Br4923          ------------------------------------------MPGQSHKE
                                                                                      

Mflv_4990|M.gilvum_PYR-GCK          VA-DTARLGE--------------------------LCERMQGLVRKAGV
MSMEG_3934|M.smegmatis_MC2_155      AA-DTARLSE--------------------------LCRRMQSLVNKAGL
MMAR_3410|M.marinum_M               VT-ALARK-----------------------------GKRAREIVYGAGL
Mb2073c|M.bovis_AF2122/97           TG-RIVFTSS-------------------------GHQPRVEQMLADCGL
Rv2047c|M.tuberculosis_H37Rv        TG-RIVFTSS-------------------------GHQPRVEQMLADCGL
MUL_2265|M.ulcerans_Agy99           TG-RIVFPSSPHVYRPGLPMPATEHGAVAPASAEGRHKAGVEQMLQESGA
MAV_5062|M.avium_104                --------------------------------------------------
Mvan_2632|M.vanbaalenii_PYR-1       PD-VVHAVS-----------------------------ARLRAAFESAPM
TH_4230|M.thermoresistible__bu      VE-EAA--------------------------------AKVRALVTDLDV
MLBr_00955|M.leprae_Br4923          PHR------------------------------------------RATST
                                                                                      

Mflv_4990|M.gilvum_PYR-GCK          DDATAADMLAAYHAM----GPGAVVAVRSSATGEDGADASFAGMNATLTN
MSMEG_3934|M.smegmatis_MC2_155      SPSVRDATLAAYRAL----GTDVVVAVRSSATGEDGRDASFAGMNRTITN
MMAR_3410|M.marinum_M               PEDLASEIVAAYRIMQEEYGEDVSLAVRSSATAEDLPTASFAGQQETFLN
Mb2073c|M.bovis_AF2122/97           EWVAVRCALIFGRNVDNWVQRLFALPVLPAGYADRVVQVVHSDDAQRLLV
Rv2047c|M.tuberculosis_H37Rv        EWVAVRCALIFGRNVDNWVQRLFALPVLPAGYADRVVQVVHSDDAQRLLV
MUL_2265|M.ulcerans_Agy99           QWVAVRSALIVGRNIDNWVRRLFALPAFPDGSADDVLQVVHLDDVLRLLT
MAV_5062|M.avium_104                --------------------------------------------------
Mvan_2632|M.vanbaalenii_PYR-1       SEELRDQVAAAHSTLG-----AAASAVRSSATAEDLPEASFAGQQDTFLN
TH_4230|M.thermoresistible__bu      PADIASAITAAYNKLG----SDAAVAVRSSGTAEDMAEASFAGQYDTYLD
MLBr_00955|M.leprae_Br4923          PRSLKQATSELRWALSLAAPESPAFMRHLLGNAHDKVDITTSSEHVAAFT
                                                                                      

Mflv_4990|M.gilvum_PYR-GCK          ----------------ITGDDGLVTAVTRCWMSLFSPRVITYRASRGFLG
MSMEG_3934|M.smegmatis_MC2_155      ----------------VMGEVALLDAVTQCWMSLFSPRVITYRASRGFTA
MMAR_3410|M.marinum_M               ----------------IKGEESLLDACRRCFASLFTDRAIHYRVDQGFDH
Mb2073c|M.bovis_AF2122/97           RALLDTVIDSGPVNLAAPGELTFRRIAAALGRPMVPIGSPVLRRVTSFAE
Rv2047c|M.tuberculosis_H37Rv        RALLDTVIDSGPVNLAAPGELTFRRIAAALGRPMVPIGSPVLRRVTSFAE
MUL_2265|M.ulcerans_Agy99           RAVSDVGAGTGPVNLAAPGLPTLREIATALRRPILPVG-AALRRIGSVAE
MAV_5062|M.avium_104                --------------------------------------------------
Mvan_2632|M.vanbaalenii_PYR-1       ----------------IVGAEALCEAIKRCWSSLWSARAIAYRRDNDIGH
TH_4230|M.thermoresistible__bu      ----------------VVGTTAVLDAVKRCWASLYTTRAVAYRSGKELDT
MLBr_00955|M.leprae_Br4923          -----------------EHAIVLLNGNAHQTRELLGGKGYNINAMR----
                                                                                      

Mflv_4990|M.gilvum_PYR-GCK          -TPAMAVVVQKMIDSEKS--GVAFTADPSTGARDRVVIEAAFGLGEVVVS
MSMEG_3934|M.smegmatis_MC2_155      -APAMAVVVQQMLSADRA--GVAFTSDPSTGDADHIVIEAAFGQGEVVVS
MMAR_3410|M.marinum_M               FKVALSIGIMKMVRSDLASSGVMFTLDTESGFNDVVFVTGAYGLGENVVQ
Mb2073c|M.bovis_AF2122/97           LELLHSAPLMDVTLLRDRWGFQPAWNAEECLEDFTLAVRGRIGLGKRTFS
Rv2047c|M.tuberculosis_H37Rv        LELLHSAPLMDVTLLRDRWGFQPAWNAEECLEDFTLAVRGRIGLGKRTFS
MUL_2265|M.ulcerans_Agy99           FQLVQGVPVMDTARLHDEWKFQPAFTAEESVEDFALAVRGRVSLGRRVVS
MAV_5062|M.avium_104                --------------------------------------------------
Mvan_2632|M.vanbaalenii_PYR-1       EDISIAVVVQSMVPATVAG--VLFTADPISGRRDRIVIEAAAEPGEAVVG
TH_4230|M.thermoresistible__bu      STVKLAVVVQEMVEAEVSG--VMFTANPFTTATDELVINASWGLGEGIVS
MLBr_00955|M.leprae_Br4923          -RHQLAVPPAFCITTEVGVRYLAAPTPTMEAIWNDVLDQMRWLEAETSRT
                                                                                      

Mflv_4990|M.gilvum_PYR-GCK          GSVEPDTYVVSKETMEP-----IDVRLGNKT-----------------FK
MSMEG_3934|M.smegmatis_MC2_155      GKVEPDTYVIDKRTLEV-----RDVRIGFKA-----------------IK
MMAR_3410|M.marinum_M               GAVDPDEFYVHKPTYQAGHRAVLRRLIGDKA-----------------VK
Mb2073c|M.bovis_AF2122/97           LPWRLANIQDLPAVDSPADDGVAPRLAGPEG-----------------AN
Rv2047c|M.tuberculosis_H37Rv        LPWRLANIQDLPAVDSPADDGVAPRLAGPEG-----------------AN
MUL_2265|M.ulcerans_Agy99           LPWRLANIQDLPAIDASAQDGVVPRLAGPEG-----------------VN
MAV_5062|M.avium_104                --------------------------------------------------
Mvan_2632|M.vanbaalenii_PYR-1       GGMTPDRWVLDAVTRRPIDAPERALLTSEQLDSLVDLGARATAAFGIPQD
TH_4230|M.thermoresistible__bu      GILTPDQFTLDKADLTVRDVTIGPKEVRVVRNPETGQG----TVTLDNDE
MLBr_00955|M.leprae_Br4923          FGWGPRPLLVSIRSGAVQSMPGMMDTILNLG-------------------
                                                                                      

Mflv_4990|M.gilvum_PYR-GCK          IVRGEDGSDTVVQLDDATAASR-------VLTDEELHSVAELAVATERHN
MSMEG_3934|M.smegmatis_MC2_155      IVRGDDGADSMVQLERSQAEAR-------VLDDDALRKIATLAVATETHN
MMAR_3410|M.marinum_M               MVFVEGGTKQTTRNIPTPKADRAH----FCITDEDVLELAGYALAIEQHY
Mb2073c|M.bovis_AF2122/97           GEFDTPIDPRFPTYLATNLSEALPGPFSPSSASVTVRGLRAGGVGIAERL
Rv2047c|M.tuberculosis_H37Rv        GEFDTPIDPRFPTYLATNLSEALPGPFSPSSASVTVRGLRAGGVGIAERL
MUL_2265|M.ulcerans_Agy99           GEFDTPIDPRFPTFLATNLSEALPGPFSPSSASVTVRGLRAGGVGIAERL
MAV_5062|M.avium_104                --------------------------------------------------
Mvan_2632|M.vanbaalenii_PYR-1       LEWAVDDDGRCWLLQSRPITSLFPIPPATRPGLRVYLPVMLIAQGIAEPM
TH_4230|M.thermoresistible__bu      ASRARRTLDDAALVRLGDIGRRIEEHFDSLPQDVEWAYADDTFYVLQSRA
MLBr_00955|M.leprae_Br4923          -----------------------------------INDPVEQALAAASPS
                                                                                      

Mflv_4990|M.gilvum_PYR-GCK          GCPQDTEWAIA--DGAAYLVQAR--------PITTLGHTTPP--------
MSMEG_3934|M.smegmatis_MC2_155      GCPQDIEWVIA--DGAVWLVQAR--------PITTLGSAGST--------
MMAR_3410|M.marinum_M               GRPMDIEWAKDGLDGKLYIVQAR--------PETAASQRSMTTVETYVLE
Mb2073c|M.bovis_AF2122/97           RPSGVIQREIAMRTVAVFAHRLYGAITSAHFMAATVPFAKPATIVSNSGF
Rv2047c|M.tuberculosis_H37Rv        RPSGVIQREIAMRTVAVFAHRLYGAITSAHFMAATVPFAKPATIVSNSGF
MUL_2265|M.ulcerans_Agy99           RPGGVIQREIAMRTVAVFAHRLYGAITSAHFMAETVPFAKPAMIVSNSGF
MAV_5062|M.avium_104                --------------------------------------------------
Mvan_2632|M.vanbaalenii_PYR-1       TPSGNAFFRTMVGGWFRYWISGRRPRASDADPDWMPIVADRLFLDVTPVL
TH_4230|M.thermoresistible__bu      VTGVDFTWDDDVDAWQWSRPHADTIWTRGFADEYWTGAITPLFYSVRGAE
MLBr_00955|M.leprae_Br4923          PIPQTFARDTRLRFIRTYR-------------------------------
                                                                                      

Mflv_4990|M.gilvum_PYR-GCK          -ARTEH--------------------------------------VVLARG
MSMEG_3934|M.smegmatis_MC2_155      -AGDEP--------------------------------------SVLIRG
MMAR_3410|M.marinum_M               GSGEQR--------------------------------------EILTEG
Mb2073c|M.bovis_AF2122/97           FGPSMA--------------------------------------SLPIFG
Rv2047c|M.tuberculosis_H37Rv        FGPSMA--------------------------------------SLPIFG
MUL_2265|M.ulcerans_Agy99           FGPSMG--------------------------------------SLPIFG
MAV_5062|M.avium_104                MTREVA--------------------------------------SWWRYA
Mvan_2632|M.vanbaalenii_PYR-1       QRPRLA--------------------------------------ARVLSN
TH_4230|M.thermoresistible__bu      QTSSYQRSAKLWGADRLAALPQFKYHKAEVYFNVENQEEFLRYTCPPMFR
MLBr_00955|M.leprae_Br4923          ---------------------------------------------RIVDP
                                                                                      

Mflv_4990|M.gilvum_PYR-GCK          LAAAPGIASGKVRVLQTPD-------EGHRLQEGEILVAQ-------MTN
MSMEG_3934|M.smegmatis_MC2_155      LPAAPGVASGRVRVLLAPD-------DGDKLTDGEILVAP-------TTN
MMAR_3410|M.marinum_M               RSVGEKVASGVVKRIDDLE-------RLSDFKPGQVLVAD-------TTT
Mb2073c|M.bovis_AF2122/97           AQRPPSESSRARRWLRTLRNIGVFGVNLVGLSAGSPRDTD-------AYV
Rv2047c|M.tuberculosis_H37Rv        AQRPPSESSRARRWLRTLRNIGVFGVNLVGLSAGSPRDTD-------AYV
MUL_2265|M.ulcerans_Agy99           EERPPAESSFVRRQLCTVRNIGVFGVNLVGLSAGSALDTN-------DFI
MAV_5062|M.avium_104                TSAPGLARPVDQQFAQAFK------------MLEYAMRVH-------VTE
Mvan_2632|M.vanbaalenii_PYR-1       FGMKDPAGSAALRKWLSQNSGRLPRPDRAAPPRGLLVLLPSLLAGTVASI
TH_4230|M.thermoresistible__bu      AAASGYLPPSRAAAVAEDPFSWAGYAKIHARILGLDITQS--FHKWIASV
MLBr_00955|M.leprae_Br4923          LNPPPANTYDQLRAAIESIFSSWNSPRAVAYRTHYGLDDQ-------SGT
                                                                                      

Mflv_4990|M.gilvum_PYR-GCK          PDWLPTIRRAAALVTDTGGMTCHAAIVARELGVPCIVGTRTGT-------
MSMEG_3934|M.smegmatis_MC2_155      PDWLPTIRRAAALVTETGGMTCHAAIVARELGVPCVVGARSAT-------
MMAR_3410|M.marinum_M               PDWEPVMKIAAAIVTNRGGRTCHAAIIARELGIPAVVGAGDAT-------
Mb2073c|M.bovis_AF2122/97           ADVDRLERLAFDNLATHDDRRLLSLILLARDHVVHGWVLASGS-------
Rv2047c|M.tuberculosis_H37Rv        ADVDRLERLAFDNLATHDDRRLLSLILLARDHVVHGWVLASGS-------
MUL_2265|M.ulcerans_Agy99           ADVDRLEQLAGGDVTTLDDRRLLSLILLARDHVVHGWVLASGS-------
MAV_5062|M.avium_104                TFVAQGIFDALGKLAESAGRPGLHLELSTGYGQMVETELVAAL-------
Mvan_2632|M.vanbaalenii_PYR-1       AAPTRARRRIVAGADAELARLEQQAEMLSAPDEQLRFVERELP-------
TH_4230|M.thermoresistible__bu      EDYMQNRIEEADGLGDEELRKLTDRALQKYIDDRMEFVEGLLYNMWSGFQ
MLBr_00955|M.leprae_Br4923          AVIVQAMVFGNQGAYSGAGTLFSRNPITRESKLFGEWLPGGQG-------
                                                              :                       

Mflv_4990|M.gilvum_PYR-GCK          ---RDLHDGTTVTVDGARGEVASGVTEPAPQM--TVSPRSAP-------A
MSMEG_3934|M.smegmatis_MC2_155      ---VALAVGSMVTVDGTRGEVTTGRLPETVRT--TTTPQEPA-------P
MMAR_3410|M.marinum_M               ---TNVPDGQLVTVSCVEGDTGR-VYRGEVGF--HVDRTEVA-------D
Mb2073c|M.bovis_AF2122/97           ---FMLCAAFNVLLRGLCGRDTAPAAGPELVS--ARSVEAVQ-------R
Rv2047c|M.tuberculosis_H37Rv        ---FMLCAAFNVLLRGLCGRDTAPAAGPELVS--ARSVEAVQ-------R
MUL_2265|M.ulcerans_Agy99           ---FMLCAAFNVLLRAVSGRDTAPAAGPELVS--ARSVEAVQ-------R
MAV_5062|M.avium_104                ---HEVAQG-RAEMAEFLARYGYRCAGEIEVS--NPSWRERP-------E
Mvan_2632|M.vanbaalenii_PYR-1       ---AATCDMVLRQLAAAYGEWLLRVVIERLVRRWLGSSTGFA-------P
TH_4230|M.thermoresistible__bu      IHASLVLNGLGTLLAKWYDGDNQMIFVDLITGLPQRTITLQENLDLWDLA
MLBr_00955|M.leprae_Br4923          ---DDVVSGLVEVQPITSLRDEQPTVYDELVDTAGRLERLGS--------
                                                                                      

Mflv_4990|M.gilvum_PYR-GCK          PVTAEVTGTRVYVNLAMP-ESAETVAAQPVDGVGLLRAEFMLTEALGG--
MSMEG_3934|M.smegmatis_MC2_155      HITGEATGTKVYVNLAMP-DSAEAVAAQDVDGVGLLRAEFMLTEALAG--
MMAR_3410|M.marinum_M               LAR---PRTEVMVNLGNP-DLAFKTSFLPNDGVGLARMEFIVGEYIKVHP
Mb2073c|M.bovis_AF2122/97           LVAAARRDPVVIRLLAEPGERLDKLAVEAPEFHSAVLAELTLIGHRGP--
Rv2047c|M.tuberculosis_H37Rv        LVAAARRDPVVIRLLAEPGERLDKLAVEAPEFHSAVLAELTLIGHRGP--
MUL_2265|M.ulcerans_Agy99           LVDAARHDEAVIRLLSEPGDRLGKLAVAAPHFYDAVRQELSLIGHRGP--
MAV_5062|M.avium_104                LVK------RMVDKYKAAPTRKNLAAAATARTRARQQAERELLAALPR--
Mvan_2632|M.vanbaalenii_PYR-1       VLRWLPHDPTIAMGAALARLAREHAAAGIEPGPESAGVSEFLATFGHRAP
TH_4230|M.thermoresistible__bu      AEIRRSPALRKLFEQSEPHEFFDKLAVHPDGAEAHRRYQQLLKDHGHRG-
MLBr_00955|M.leprae_Br4923          --------DVQEIEFTTEDSKLWLLQTRVAERSAQVAVRLALQLWQEG--
                                                                             :        

Mflv_4990|M.gilvum_PYR-GCK          --------------RHPRDLIARGEQN---MLVEKMVDSVGRIAAAFS--
MSMEG_3934|M.smegmatis_MC2_155      --------------RHPRDLITKGEQD---TLVDAMAAAVTRIGTAFA--
MMAR_3410|M.marinum_M               LALLHPDKVDDPEARRTIERLTRGYSDGAEFFVQRLSEGIGTIAAAFW--
Mb2073c|M.bovis_AF2122/97           ---------------AEVEMAATSYADNPELLVRMVAKTLRAVPAPQP--
Rv2047c|M.tuberculosis_H37Rv        ---------------AEVEMAATSYADNPELLVRMVAKTLRAVPAPQP--
MUL_2265|M.ulcerans_Agy99           ---------------AEVEMMSTSYADNPELLVGMVAKTLSTSSVPQP--
MAV_5062|M.avium_104                -------------------------------WKRPLGRLLIKLAATFI--
Mvan_2632|M.vanbaalenii_PYR-1       --------------DREVDLGLPRLSDDPTYVVELINGYLRSGALDTF--
TH_4230|M.thermoresistible__bu      --------------HADRDFIFPRRIEDPSIDYRSLQALLSGDGMQRPDE
MLBr_00955|M.leprae_Br4923          ------------------------LIDDAEALRRVTPVHVETVLLPVLQ-
                                                                           :          

Mflv_4990|M.gilvum_PYR-GCK          ---PRP-VVYRATDFRSNEFRGLTGGAEYEPVEH----------------
MSMEG_3934|M.smegmatis_MC2_155      ---PRP-VIYRAMDFRTNEFRGLAGGEQFEPVEH----------------
MMAR_3410|M.marinum_M               ---PKP-VVVRMSDFKSNEYASLIGGSGFEPTES----------------
Mb2073c|M.bovis_AF2122/97           ---PTPVIPLRAKPVALLAARQLRDREVRRDRMV----------------
Rv2047c|M.tuberculosis_H37Rv        ---PTPVIPLRAKPVALLAARQLRDREVRRDRMV----------------
MUL_2265|M.ulcerans_Agy99           ---PQPSIPLQAKPIAVLAARQLRDREARRDKMV----------------
MAV_5062|M.avium_104                ---PLR--------------------EEGKSALA----------------
Mvan_2632|M.vanbaalenii_PYR-1       ---ETGVHEARAASDGLITGVRRVKGPVRAAVLRNLLARHLALGGLRERP
TH_4230|M.thermoresistible__bu      QERKQAAKREAATADVIARLEAKPFGRLRADLFRMLLDYAHRFMVLRDDE
MLBr_00955|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_4990|M.gilvum_PYR-GCK          -----NPMIGFRGCYRYVK----EPELFALELEALARVRERS---PNVAL
MSMEG_3934|M.smegmatis_MC2_155      -----NPMIGYRGCYRYIK----EPDLFALELSALARAREHT---PNIHL
MMAR_3410|M.marinum_M               -----NPMIGFRGASRYAHP--AYAEGFALECRAMQRVRDQMG-LTNVVI
Mb2073c|M.bovis_AF2122/97           -----RAIWVLRALLREYGRRLTEAGVFDTPDDVFYLLVDEID-ALPADV
Rv2047c|M.tuberculosis_H37Rv        -----RAIWVLRALLREYGRRLTEAGVFDTPDDVFYLLVDEID-ALPADV
MUL_2265|M.ulcerans_Agy99           -----RAIWVLRALLREHGRRLAEAGVLHASDDVFYLLVDEVD-ALPADV
MAV_5062|M.avium_104                -----MAFDGARAACGIRGAELAAAGVVDRSEDVFYLTIDEIRGTPPAEA
Mvan_2632|M.vanbaalenii_PYR-1       KFDMVRAMALGRRTLRRCGAALVERGLLDDADDVFFLDGADVRAALAGRA
TH_4230|M.thermoresistible__bu      RHYVDRATMSKKRAFLELGRRLLARDLIERLDDVYFLTKDELYELMAERA
MLBr_00955|M.leprae_Br4923          ------PENHLSATLLAKG----TPTCPGVISGKAYTEVDEALDAAESAE
                                          .                                           

Mflv_4990|M.gilvum_PYR-GCK          MIPFVRTRWEL-------EECLSLVDASPLGR-QRGLHRWVMAE--VPSV
MSMEG_3934|M.smegmatis_MC2_155      MIPFVRTRWEL-------EECLALVDASPLRR-HRNLHRWVMAE--VPSV
MMAR_3410|M.marinum_M               MLPFVRRVAEA-------DLVLETMAEHGLRRGENGLKVYAMCE--IPNN
Mb2073c|M.bovis_AF2122/97           SGLVARRRAEQ-------RRLAGIVPPTVFSGSWEPSPSSAAAL--AAGD
Rv2047c|M.tuberculosis_H37Rv        SGLVARRRAEQ-------RRLAGIVPPTVFSGSWEPSPSSAAAL--AAGD
MUL_2265|M.ulcerans_Agy99           AELVARRRAEQ-------RRLTAVVPPTVFSGKWEPSTASAAAL--TAEG
MAV_5062|M.avium_104                RALIARRRELR-------AAYEQIDVPDAWIGPPVAVSVANSGN--SRVG
Mvan_2632|M.vanbaalenii_PYR-1       CDLRARAAADHRSF---RRELRRRRVPRVLTSEGEAVYGFDTATPGAETD
TH_4230|M.thermoresistible__bu      PQALVRAKIAGRRKQFEAFDRKDAIPPMYLQHGREWIDPTEISGGDVDPR
MLBr_00955|M.leprae_Br4923          QVILVRDHTRP-------DDVLGMLASQGVVTEVGGAASHAAVVS-----
                                        .*                                            

Mflv_4990|M.gilvum_PYR-GCK          VHWLPEYIGMGIDGVS--IGSND-LTQLLLGVDRDSDVCAELFDESDPAV
MSMEG_3934|M.smegmatis_MC2_155      VHWLPEYVGMGIDGVS--IGSND-LTQLMLGVDRDSETCAELFDESDAAV
MMAR_3410|M.marinum_M               VILIDQFAKR-FDGFS--IGSND-LTQLTLGVDRDSEIVAFDYDERDDGV
Mb2073c|M.bovis_AF2122/97           TLRGVGVCGGRVRGRVRIVRPET-IDDLQPGEILVAEVTDVGYTAAFCYA
Rv2047c|M.tuberculosis_H37Rv        TLRGVGVCGGRVRGRVRIVRPET-IDDLQPGEILVAEVTDVGYTAAFCYA
MUL_2265|M.ulcerans_Agy99           TLRGVGVCGGRVRGRVRIVRPET-IDELEPGEILVAEVTDVGYTAAFCYA
MAV_5062|M.avium_104                SLSGVAAAHGVAEGPARVLASADDLDDLEPDEILVCRTTDPSWASAFHLA
Mvan_2632|M.vanbaalenii_PYR-1       VLIGTALSPGVHVGTVRVLDSPV-GANLQPGEVIVAASTDPGWTPLFLLA
TH_4230|M.thermoresistible__bu      ALQGLPTSPGTVEGRARVVRELDGIGCLEKGDILITNSTDPGWTPVFAII
MLBr_00955|M.leprae_Br4923          RELSRVAVVGCGQGTAVSLAGKQITVDGDKGEVRQGNLTLSAWSENETPE
                                                 *    :           .           :       

Mflv_4990|M.gilvum_PYR-GCK          LHAIRRIVDTANKFGITSSLCGQAPSTNPAFAEHLVRLGITSVSVNPDAV
MSMEG_3934|M.smegmatis_MC2_155      LDAISRIISTANRLGITSSLCGQAPSTRPEFAEHLVRMGITSVSVNPDAA
MMAR_3410|M.marinum_M               KEMIRLAVEGCRRNGIHSGLCGQAPSDYPDMAEFLVRAGIDSVSLNPDVV
Mb2073c|M.bovis_AF2122/97           AAVVTELGGPMSHAAVVAREFGFPCVVDAQGATRFLPPGALVEVDGATGE
Rv2047c|M.tuberculosis_H37Rv        AAVVTELGGPMSHAAVVAREFGFPCVVDAQGATRFLPPGALVEVDGATGE
MUL_2265|M.ulcerans_Agy99           AAVVTELGGPMSHAAVVAREFGFPCVVDAQGATRFLPPGALIEVDGTTGE
MAV_5062|M.avium_104                AGAVIDIGSTSSHGAIIAREMGMPCVIGTGNGTQLLRTGDFIRVDGSTGI
Mvan_2632|M.vanbaalenii_PYR-1       GALVMEVGGVMSHGALVAREYGLPAVAGIGNAMTRLRSGQRVRVDGTAGS
TH_4230|M.thermoresistible__bu      GGLILETGGMLAHGSCLSREYGLPAVT-VANACSHIADGAHIRVDGHTGM
MLBr_00955|M.leprae_Br4923          LRELADIARRISPLRVHMTEDHTRLDDSSDTAVRLAINTGHADVVSATPL
                                       :                           .             .    

Mflv_4990|M.gilvum_PYR-GCK          DATRRVIAAAERRIMLAAARSLPEDQ----------------
MSMEG_3934|M.smegmatis_MC2_155      GAARRAVAAAERRLLLDSVRHPRHAPTASPRNPL--------
MMAR_3410|M.marinum_M               VKTTRQILDLEQQVVPLQ------------------------
Mb2073c|M.bovis_AF2122/97           IHVVELASEDGPALPGSDLSR---------------------
Rv2047c|M.tuberculosis_H37Rv        IHVVELASEDGPALPGSDLSR---------------------
MUL_2265|M.ulcerans_Agy99           IQVLELAAEGDSSVTQSDPADLA-------------------
MAV_5062|M.avium_104                VTVLQEAKRA--------------------------------
Mvan_2632|M.vanbaalenii_PYR-1       VTLLDSVAPDGAAEDPAPTADRAAGSGPRPAPRPRPVSPDSR
TH_4230|M.thermoresistible__bu      VSVLDDELAAAR------------------------------
MLBr_00955|M.leprae_Br4923          IVMMTTLRLQDSKDSSAKS-----------------------