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VRIAVTGASGVLGRGLTARLLSQGHEVVGIARHRPDSWPSSADFIAADIRDATAVESAMTGADVVAHCAW VRGRNDHINIDGTANVLKAMAETGTGRIVFTSSGHQPRVEQMLADCGLEWVAVRCALIFGRNVDNWVQRL FALPVLPAGYADRVVQVVHSDDAQRLLVRALLDTVIDSGPVNLAAPGELTFRRIAAALGRPMVPIGSPVL RRVTSFAELELLHSAPLMDVTLLRDRWGFQPAWNAEECLEDFTLAVRGRIGLGKRTFSLPWRLANIQDLP AVDSPADDGVAPRLAGPEGANGEFDTPIDPRFPTYLATNLSEALPGPFSPSSASVTVRGLRAGGVGIAER LRPSGVIQREIAMRTVAVFAHRLYGAITSAHFMAATVPFAKPATIVSNSGFFGPSMASLPIFGAQRPPSE SSRARRWLRTLRNIGVFGVNLVGLSAGSPRDTDAYVADVDRLERLAFDNLATHDDRRLLSLILLARDHVV HGWVLASGSFMLCAAFNVLLRGLCGRDTAPAAGPELVSARSVEAVQRLVAAARRDPVVIRLLAEPGERLD KLAVEAPEFHSAVLAELTLIGHRGPAEVEMAATSYADNPELLVRMVAKTLRAVPAPQPPTPVIPLRAKPV ALLAARQLRDREVRRDRMVRAIWVLRALLREYGRRLTEAGVFDTPDDVFYLLVDEIDALPADVSGLVARR RAEQRRLAGIVPPTVFSGSWEPSPSSAAALAAGDTLRGVGVCGGRVRGRVRIVRPETIDDLQPGEILVAE VTDVGYTAAFCYAAAVVTELGGPMSHAAVVAREFGFPCVVDAQGATRFLPPGALVEVDGATGEIHVVELA SEDGPALPGSDLSR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2073c | - | - | 100% (854) | hypothetical protein Mb2073c |
| M. bovis AF2122 / 97 | Mb1899 | - | 5e-70 | 31.84% (738) | hypothetical protein Mb1899 |
| M. bovis AF2122 / 97 | Mb1158c | ppdK | 4e-09 | 34.85% (132) | pyruvate phosphate dikinase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0493 | - | 8e-39 | 31.24% (573) | pyruvate, water dikinase |
| M. tuberculosis H37Rv | Rv2047c | - | 0.0 | 100.00% (854) | hypothetical protein Rv2047c |
| M. leprae Br4923 | MLBr_01942 | - | 2e-09 | 32.76% (116) | putative cholesterol dehydrogenase |
| M. abscessus ATCC 19977 | MAB_0994 | - | 8e-09 | 26.98% (278) | putative NAD-dependent epimerase/dehydratase |
| M. marinum M | MMAR_3024 | - | 0.0 | 76.08% (882) | hypothetical protein MMAR_3024 |
| M. avium 104 | MAV_2451 | - | 0.0 | 73.32% (877) | hypothetical protein MAV_2451 |
| M. smegmatis MC2 155 | MSMEG_3934 | - | 2e-17 | 46.02% (113) | phosphoenolpyruvate synthase |
| M. thermoresistible (build 8) | TH_4230 | - | 1e-22 | 29.28% (345) | PUTATIVE putative phosphoenolpyruvate synthase |
| M. ulcerans Agy99 | MUL_2265 | - | 0.0 | 75.40% (882) | hypothetical protein MUL_2265 |
| M. vanbaalenii PYR-1 | Mvan_2632 | - | 2e-27 | 31.04% (422) | pyruvate, water dikinase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2073c|M.bovis_AF2122/97 ---------------------------------MRIAVTGASGVLGRGLT
Rv2047c|M.tuberculosis_H37Rv ---------------------------------MRIAVTGASGVLGRGLT
MMAR_3024|M.marinum_M ---------------------------------MRVAVTGAGGVLGRGLA
MUL_2265|M.ulcerans_Agy99 ---------------------------------MRVAVTGAGGVLGRGLA
MAV_2451|M.avium_104 ---------------------------------MRIAVTGASGVLGRGLA
MAB_0994|M.abscessus_ATCC_1997 ---------------------------------MRVFVTGASGFIGSAVV
MLBr_01942|M.leprae_Br4923 -------------------MLRGVGNASLTTELGRVLVTGGSGFVGANLV
Mvan_2632|M.vanbaalenii_PYR-1 ---MTGTMIHWLTDAGAADPSRSGGKGAKLALLVRAGLPVPAGFVVLTEA
Mflv_0493|M.gilvum_PYR-GCK ----MFDASSRIVDLADVLDDSFGGKALGLAELTRLGLPVPPGFVIADAS
TH_4230|M.thermoresistible__bu -----MSYIVEFSEPAAVQRAVAGGKGAHLASLTTAGFTVPPGFVVTVDA
MSMEG_3934|M.smegmatis_MC2_155 MDIMSDRYVRTLDILTIADAEEAGGKGANLGELVAADLPVPHGFVVMRSA
.. *.:
Mb2073c|M.bovis_AF2122/97 ARLLSQGHEVVGIARHRPDSWPSSADFIAADIRDATAVESAMTGADVVAH
Rv2047c|M.tuberculosis_H37Rv ARLLSQGHEVVGIARHRPDSWPSSADFIAADIRDATAVESAMTGADVVAH
MMAR_3024|M.marinum_M SRLLSQGHEVVGMSRRRPDSWPSQADFVAGDIRDAAAVRRAITGADVVAH
MUL_2265|M.ulcerans_Agy99 SRLLSQGHEVVGMSRRRPDSWPSQADFVAGDIRDAAAVRRAITGADVVAH
MAV_2451|M.avium_104 ARLLSKGHDVVGIARHRPDSWSSAADFIEADIRDAAAVNRAVTSADVVAH
MAB_0994|M.abscessus_ATCC_1997 RELIDSGHTVTGLARS-----------------DSSAAALTAAGADVHR-
MLBr_01942|M.leprae_Br4923 TALLERGYQVRSFDRAP---------MPLPQHPQLEVLQGDITDATVCT-
Mvan_2632|M.vanbaalenii_PYR-1 YRRFVSDHGLDGLIRQQLGAINTGPDGDPDVVHAVSARLRAAFESAPMSE
Mflv_0493|M.gilvum_PYR-GCK GTSLGDAVTER-FSRMRAAGQTPVAVRSSAAGEDGAEHSFAGQYDTVLG-
TH_4230|M.thermoresistible__bu FDAAVTRNIGADVEKILAGTDFADADAVEEAAAKVRALVTDLDVPADIAS
MSMEG_3934|M.smegmatis_MC2_155 YLDSVRMGGVEAELAALHTEALTHAADTARLSELCRRMQSLVNKAGLSPS
Mb2073c|M.bovis_AF2122/97 CAWVRGR------NDHINIDGTANVLKAMAETGTGRIVFTSS--------
Rv2047c|M.tuberculosis_H37Rv CAWVRGR------NDHINIDGTANVLKAMAETGTGRIVFTSS--------
MMAR_3024|M.marinum_M CAWARNPGPDGRISQQINIDGTRNVLDAMAACGTGRIVFPSSPHVYRPGV
MUL_2265|M.ulcerans_Agy99 CAWARNPGPDGRISQQINIDGTRNVLDAMAACGTGRIVFPSSPHVYRPGL
MAV_2451|M.avium_104 FAWTHDT--QERTGSQVNIAGTANVLAAMAETSARRIVFPSSPHVYGGG-
MAB_0994|M.abscessus_ATCC_1997 --------------------GSLDDLESLRAG------------------
MLBr_01942|M.leprae_Br4923 --------------------TAMDSIDTVFHT------------------
Mvan_2632|M.vanbaalenii_PYR-1 ELRDQVAAAHSTLGAAASAVRSSATAEDLPEAS-----------------
Mflv_0493|M.gilvum_PYR-GCK -------------------VGSVDELTAAVEKCVR---------------
TH_4230|M.thermoresistible__bu AITAAYN---KLGSDAAVAVRSSGTAEDMAEAS-----------------
MSMEG_3934|M.smegmatis_MC2_155 VRDATLAAYRALGTDVVVAVRSSATGEDGRDAS-----------------
:
Mb2073c|M.bovis_AF2122/97 -----------------GHQPRVEQMLADCGLEWVAVRCALIFGRNVDNW
Rv2047c|M.tuberculosis_H37Rv -----------------GHQPRVEQMLADCGLEWVAVRCALIFGRNVDNW
MMAR_3024|M.marinum_M PMPATEHGAVAPASAEGRHKAGVEQMLQESGAQWVAVRSALIVGRNIDNW
MUL_2265|M.ulcerans_Agy99 PMPATEHGAVAPASAEGRHKAGVEQMLQESGAQWVAVRSALIVGRNIDNW
MAV_2451|M.avium_104 DTPRSEAEAPAPSAADAVQQARVEEMLVASGLESVTIRCALVVGRNVDNW
MAB_0994|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01942|M.leprae_Br4923 --------------------------------------------------
Mvan_2632|M.vanbaalenii_PYR-1 --------------------------FAGQQDTFLNIVGAEALCEAIKRC
Mflv_0493|M.gilvum_PYR-GCK --------------------------------------------------
TH_4230|M.thermoresistible__bu --------------------------FAGQYDTYLDVVGTTAVLDAVKRC
MSMEG_3934|M.smegmatis_MC2_155 --------------------------FAGMNRTITNVMGEVALLDAVTQC
Mb2073c|M.bovis_AF2122/97 VQRLFALPVLPAGYADRVVQVVHSDDAQRLLVRALLDTVIDSGPVNLAAP
Rv2047c|M.tuberculosis_H37Rv VQRLFALPVLPAGYADRVVQVVHSDDAQRLLVRALLDTVIDSGPVNLAAP
MMAR_3024|M.marinum_M VRRLFALPAFPDGSADDVLQVVHLDDVLRLLTRAVSDVGAGTGPVNLAAP
MUL_2265|M.ulcerans_Agy99 VRRLFALPAFPDGSADDVLQVVHLDDVLRLLTRAVSDVGAGTGPVNLAAP
MAV_2451|M.avium_104 VRRVLALPAFPGGTVDRPIQLVHLDDALRLLESAVLSHEIPSGTVNLAAP
MAB_0994|M.abscessus_ATCC_1997 -----------AVAADGVAHLAFVHDFEN-----------YAEAVNADKR
MLBr_01942|M.leprae_Br4923 -----------AAIIELMGGASVTDEYRQ-----------RSYTVNVGGT
Mvan_2632|M.vanbaalenii_PYR-1 WSSLWSARAIAYRRDNDIGHEDISIAVVVQSMVPATVAGVLFTADPISGR
Mflv_0493|M.gilvum_PYR-GCK ------SAGSERAAAYQDGGAAARMHLVVQQMVDARAAGVVFTADPTSGR
TH_4230|M.thermoresistible__bu WASLYTTRAVAYRSGKELDTSTVKLAVVVQEMVEAEVSGVMFTANPFTTA
MSMEG_3934|M.smegmatis_MC2_155 WMSLFSPRVITYRASRG-FTAAPAMAVVVQQMLSADRAGVAFTSDPSTGD
.
Mb2073c|M.bovis_AF2122/97 GELTFRRIAAALGRPMVPIGS-------------------------PVLR
Rv2047c|M.tuberculosis_H37Rv GELTFRRIAAALGRPMVPIGS-------------------------PVLR
MMAR_3024|M.marinum_M GLPTLREIAMALRRPILPVG--------------------------AVLR
MUL_2265|M.ulcerans_Agy99 GLPTLREIATALRRPILPVG--------------------------AALR
MAV_2451|M.avium_104 GTTTFRRIAATLRRPVLRLG------------------------------
MAB_0994|M.abscessus_ATCC_1997 AIATIGEALAGTERPFVVTS------------------------------
MLBr_01942|M.leprae_Br4923 ENLLRAGQKSGVKRFVYTAS------------------------------
Mvan_2632|M.vanbaalenii_PYR-1 RDRIVIEAAAEPGEAVVGGG----------------------------MT
Mflv_0493|M.gilvum_PYR-GCK RDLLVIDAVRGLGESLVDGS---------------------------TAS
TH_4230|M.thermoresistible__bu TDELVINASWGLGEGIVSGILTPDQFTLDKADLTVRDVTIGPKEVRVVRN
MSMEG_3934|M.smegmatis_MC2_155 ADHIVIEAAFGQGEVVVSGK------------------------------
. .
Mb2073c|M.bovis_AF2122/97 RVTSFAELELLHSAPLMDVTLLRDRWGFQPAWNAEECLEDFT-LAVRGRI
Rv2047c|M.tuberculosis_H37Rv RVTSFAELELLHSAPLMDVTLLRDRWGFQPAWNAEECLEDFT-LAVRGRI
MMAR_3024|M.marinum_M RIGSVAEFQLVQGVPVMDTARLHDEWKFQPAFTAEESVEDFA-LAVRGRV
MUL_2265|M.ulcerans_Agy99 RIGSVAEFQLVQGVPVMDTARLHDEWKFQPAFTAEESVEDFA-LAVRGRV
MAV_2451|M.avium_104 -RPAPAELEPVLSAPLMDTALLHERWGFRPAWQCGECVEDMA-LAVRGRV
MAB_0994|M.abscessus_ATCC_1997 ---GLAGFGLGRPLTEEDAAAPESPR---------LSEEALN-LADRG--
MLBr_01942|M.leprae_Br4923 ----NSVVMGGTPITGGDETMPYTKRFNDLYTETKVVAEKFV-LSQNG--
Mvan_2632|M.vanbaalenii_PYR-1 PDRWVLDAVTRRPIDAPERALLTSEQLDSLVDLGARATAAFG-IPQDLEW
Mflv_0493|M.gilvum_PYR-GCK DHFVLTHAGDTVTTEASSQPALADDEIDRIRTGALLAAAHWG-RPLDLEW
TH_4230|M.thermoresistible__bu PETGQGTVTLDNDEASRARRTLDDAALVRLGDIGRRIEEHFDSLPQDVEW
MSMEG_3934|M.smegmatis_MC2_155 -VEPDTYVIDKRTLEVRDVRIGFKAIKIVRGDDGADSMVQLE-RSQAEAR
.
Mb2073c|M.bovis_AF2122/97 GLGKRTFSLPWRLANIQDLPAVDSPADDGVAPRLAGP---EGANGEFDTP
Rv2047c|M.tuberculosis_H37Rv GLGKRTFSLPWRLANIQDLPAVDSPADDGVAPRLAGP---EGANGEFDTP
MMAR_3024|M.marinum_M SLGRRVVSLPWRLANIQDLPAVDAPAQDGVVPRLAGP---EGVNGEFDTP
MUL_2265|M.ulcerans_Agy99 SLGRRVVSLPWRLANIQDLPAIDASAQDGVVPRLAGP---EGVNGEFDTP
MAV_2451|M.avium_104 TVGRRVVSLPWRLANVADLPAVDAPAQDGVVPVPAGP---EGVNGEFDTP
MAB_0994|M.abscessus_ATCC_1997 ----------VRVSAVRLAPSVHGEGDHGFVPRLIEI---ARAKGVSAYP
MLBr_01942|M.leprae_Br4923 -----VPDGETMLTCSIRPSGIWGRGDQTMFRKAFES---VVSGHVKVLI
Mvan_2632|M.vanbaalenii_PYR-1 AVDDDGRCWLLQSRPITSLFPIPPATRPGLRVYLPVM---LIAQGIAEPM
Mflv_0493|M.gilvum_PYR-GCK AIDRDGLLWWLQARPITTLPGDPNEMDTPVTGPTHVY---TRCN-IGEMM
TH_4230|M.thermoresistible__bu AYADDTFYVLQSRAVTGVDFTWDDDVDAWQWSRPHADTIWTRGFADEYWT
MSMEG_3934|M.smegmatis_MC2_155 VLDDDALRKIATLAVATETHNGCPQDIEWVIADGAVW----LVQARPITT
Mb2073c|M.bovis_AF2122/97 IDP--RFPTYLATNLSEALPGPFSPSSASVT-------VRGLRAGGVGIA
Rv2047c|M.tuberculosis_H37Rv IDP--RFPTYLATNLSEALPGPFSPSSASVT-------VRGLRAGGVGIA
MMAR_3024|M.marinum_M IDP--RFPTFLATNLSEALPGPFSPSSASVT-------VRGLRAGGVGIA
MUL_2265|M.ulcerans_Agy99 IDP--RFPTFLATNLSEALPGPFSPSSASVT-------VRGLRAGGVGIA
MAV_2451|M.avium_104 IDP--RFPTFLATNLSEALPGPFSPSSASAT-------VRGVRAGGVTIA
MAB_0994|M.abscessus_ATCC_1997 GDGSNRWPAVHRLDAAHLFRLALENAPTGSR-------LHGVAEDGIPVR
MLBr_01942|M.leprae_Br4923 GSKNAKLDNSYVHNLVHGLILAAEHLVPGGT-------APG-QAYFINDG
Mvan_2632|M.vanbaalenii_PYR-1 TPSGNAFFRTMVGGWFRYWISGRRPRASDADPDWMPIVADRLFLDVTPVL
Mflv_0493|M.gilvum_PYR-GCK PGAFCPLTASVSGHAIDYAMQMVQVAGGVQER------YEDRARQVGYFF
TH_4230|M.thermoresistible__bu GAITPLFYSVRGAEQTSSYQRSAKLWGADRLAALPQFKYHKAEVYFNVEN
MSMEG_3934|M.smegmatis_MC2_155 LGSAGSTAGDEPSVLIRGLPAAPGVASGRVR-------VLLAPDDGDKLT
Mb2073c|M.bovis_AF2122/97 ERLRPSGVIQREIAMRTVA-VFAHRLYGAITSAHFMAATVPFAKPATIVS
Rv2047c|M.tuberculosis_H37Rv ERLRPSGVIQREIAMRTVA-VFAHRLYGAITSAHFMAATVPFAKPATIVS
MMAR_3024|M.marinum_M ERLRPGGVIQREIAMRTVA-VFAHRLYGAITSAHFMAETVPFAKPAMIVS
MUL_2265|M.ulcerans_Agy99 ERLRPGGVIQREIAMRTVA-VFAHRLYGAITSAHFMAETVPFAKPAMIVS
MAV_2451|M.avium_104 ERLRPGGLVQREIALRTVG-VFAHRLYGAITSAHFMAETVPFAKPSMIVS
MAB_0994|M.abscessus_ATCC_1997 D---IAEVIGRHLNLPVES-VPLAQAFDHFG------------------W
MLBr_01942|M.leprae_Br4923 EPINFFDFMGPIIKACGEN-WPRVRISGRLVRN------------VMAVW
Mvan_2632|M.vanbaalenii_PYR-1 QRPRLAARVLSNFGMKDPAGSAALRKWLSQNSGRLPRPDRAAPPRGLLVL
Mflv_0493|M.gilvum_PYR-GCK GHMFLNMTEGTALSSGILG-NSLEQFSLSVCGRVIDELEPGPPKPFVRKL
TH_4230|M.thermoresistible__bu QEEFLRYTCPPMFRAAASGYLPPSRAAAVAEDPFSWAGYAKIHARILGLD
MSMEG_3934|M.smegmatis_MC2_155 DGEILVAPTTNPDWLPTIRRAAALVTETGGMTCHAAIVARELGVPCVVGA
Mb2073c|M.bovis_AF2122/97 NSGFFGPSMASLPIFGAQRPPSESSRARRWLRTLRNIGVFGVNLVGLSAG
Rv2047c|M.tuberculosis_H37Rv NSGFFGPSMASLPIFGAQRPPSESSRARRWLRTLRNIGVFGVNLVGLSAG
MMAR_3024|M.marinum_M NSGFFGPSMGSLPIFGEERPPAESSFVRRQLRTVRNIGVFGVNLVGLSAG
MUL_2265|M.ulcerans_Agy99 NSGFFGPSMGSLPIFGEERPPAESSFVRRQLCTVRNIGVFGVNLVGLSAG
MAV_2451|M.avium_104 NSGFFGPSMASLPVFGEQRP-AETGWARRLLRNTRNIGVFGVNLVGLSSG
MAB_0994|M.abscessus_ATCC_1997 LGGFFAMDLPATSVLTQERLGWRPVQPG----------------------
MLBr_01942|M.leprae_Br4923 QRLHFGFGLPKPPMEP---LAVERVYLDNYFSIEKAHKELGYRPLFTTEQ
Mvan_2632|M.vanbaalenii_PYR-1 LPSLLAGTVASIAAPTRARRRIVAGADAELARLEQQAEMLSAPDEQLRFV
Mflv_0493|M.gilvum_PYR-GCK INTVRLSTFALSSAPAIRRLPQTIAAFPPITSRDPAVVLRHLEAGVDIYR
TH_4230|M.thermoresistible__bu ITQSFHKWIASVEDYMQNRIEEADGLGDEELRKLTDRALQKYIDDRMEFV
MSMEG_3934|M.smegmatis_MC2_155 RSATVALAVGSMVTVDGTRGEVTTGRLPETVRTTTTPQEPAPHITGEATG
.
Mb2073c|M.bovis_AF2122/97 SPRDTDAYVADVDRLERLAFDNLATHDDRRLLSLILLARDHVVHGWVLAS
Rv2047c|M.tuberculosis_H37Rv SPRDTDAYVADVDRLERLAFDNLATHDDRRLLSLILLARDHVVHGWVLAS
MMAR_3024|M.marinum_M SALDTNDFIADVDRLEQLAGGDVTTLDDRRLLSLILLARDHVVHGWVLAS
MUL_2265|M.ulcerans_Agy99 SALDTNDFIADVDRLEQLAGGDVTTLDDRRLLSLILLARDHVVHGWVLAS
MAV_2451|M.avium_104 AARDTDDFIADVDRLERLAG-DAAELDERRLLSLIALARDQVVHGWVLAS
MAB_0994|M.abscessus_ATCC_1997 -------LIADLEKGHYFDE------------------------------
MLBr_01942|M.leprae_Br4923 AMAECLPYYTELFEQIKVAAKPHLASIAATPRPE----------------
Mvan_2632|M.vanbaalenii_PYR-1 ERELPAATCDMVLRQLAAAYGEWLLRVVIERLVRRWLG-SSTGFAPVLRW
Mflv_0493|M.gilvum_PYR-GCK EVTLIHVRSSSRSAVAANVLESHLVRRAAKRGASDTAGSAEAIRLMTGAG
TH_4230|M.thermoresistible__bu EG-LLYNMWSGFQIHASLVLNGLGTLLAKWYDGDNQMIFVDLITGLPQRT
MSMEG_3934|M.smegmatis_MC2_155 TKVYVNLAMPDSAEAVAAQDVDGVGLLRAEFMLTEALAGRHPRDLITKG-
Mb2073c|M.bovis_AF2122/97 GSFMLCAAFNVLLRGLCGRDTAPAAGPELVSARSVEAVQRLVAAARRDPV
Rv2047c|M.tuberculosis_H37Rv GSFMLCAAFNVLLRGLCGRDTAPAAGPELVSARSVEAVQRLVAAARRDPV
MMAR_3024|M.marinum_M GSFMLCAAFNVLLRAVSGRDTAPAAGPELVSARSVEAVQRLVAAARHDEA
MUL_2265|M.ulcerans_Agy99 GSFMLCAAFNVLLRAVSGRDTAPAAGPELVSARSVEAVQRLVDAARHDEA
MAV_2451|M.avium_104 ASFMLCAAFNVLLRAVCGRDTSAPAGPELVSARSVEAMQRLVVAAQRDPN
MAB_0994|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01942|M.leprae_Br4923 --------------------------------------------------
Mvan_2632|M.vanbaalenii_PYR-1 LPHDPTIAMGAALARLAREHAAAGIEPGPESAGVSEFLATFGHRAPDREV
Mflv_0493|M.gilvum_PYR-GCK VESALMVEELTAVVSMLRRDGDAAARFLAAPAGEAVTRLRAAETPSGAAL
TH_4230|M.thermoresistible__bu ITLQENLDLWDLAAEIRR---SPALRKLFEQSEPHEFFDKLAVHPDGAEA
MSMEG_3934|M.smegmatis_MC2_155 ---EQDTLVDAMAAAVTRIGTAFAPRPVIYRAMDFRTNEFRGLAGGEQFE
Mb2073c|M.bovis_AF2122/97 VIRLLAEPGERLDKLAVEAPEFHS--AVLAELTLIGHRGPAEVEMAATS-
Rv2047c|M.tuberculosis_H37Rv VIRLLAEPGERLDKLAVEAPEFHS--AVLAELTLIGHRGPAEVEMAATS-
MMAR_3024|M.marinum_M VIRLLSEPGDRLGKLAVAAPHFYD--AVRQELSLIGHRGPAEVEMMSTS-
MUL_2265|M.ulcerans_Agy99 VIRLLSEPGDRLGKLAVAAPHFYD--AVRQELSLIGHRGPAEVEMMSTS-
MAV_2451|M.avium_104 VARVLTEPGERLDKLAVDAPEFHA--AVLAELALIGHRGPAELEMLSTS-
MAB_0994|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01942|M.leprae_Br4923 --------------------------------------------------
Mvan_2632|M.vanbaalenii_PYR-1 DLGLPRLSDDPTYVVELINGYLRS--GALDTFETGVHEARAASDGLITG-
Mflv_0493|M.gilvum_PYR-GCK RTFLDRHGHRGYRELCMRDPSWADDPDGLGAMMQVMLRGAAPENPAATA-
TH_4230|M.thermoresistible__bu HRRYQQLLKDHGHRGHADRDFIFPRRIEDPSIDYRSLQALLSGDGMQRPD
MSMEG_3934|M.smegmatis_MC2_155 PVEHNPMIGYRGCYRYIKEP----------DLFALELSALAR--------
Mb2073c|M.bovis_AF2122/97 -YADNPELLVRMVAKTLRAVPAPQPPTPVIPLRAKPVALLAARQLRDREV
Rv2047c|M.tuberculosis_H37Rv -YADNPELLVRMVAKTLRAVPAPQPPTPVIPLRAKPVALLAARQLRDREV
MMAR_3024|M.marinum_M -YADNPELLVGMVAKTLSTSSVPQPPQPSIPLQAKPIAVLAARQLRDREA
MUL_2265|M.ulcerans_Agy99 -YADNPELLVGMVAKTLSTSSVPQPPQPSIPLQAKPIAVLAARQLRDREA
MAV_2451|M.avium_104 -YADDPELLVRMVAKAMAATAAPPPQHPRIPLQAKLIAALTARQLRDREA
MAB_0994|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01942|M.leprae_Br4923 --------------------------------------------------
Mvan_2632|M.vanbaalenii_PYR-1 -VRRVKGPVRAAVLRNLLARHLALG--------------------GLRER
Mflv_0493|M.gilvum_PYR-GCK -PSDPAQSRTLRVLARLAQAG-----------------------ARGREE
TH_4230|M.thermoresistible__bu EQERKQAAKREAATADVIARLEAKPFGRLRADLFRMLLDYAHRFMVLRDD
MSMEG_3934|M.smegmatis_MC2_155 ----------------------------------------------AREH
Mb2073c|M.bovis_AF2122/97 RRDRMVRAIWVLRALLREYGRRLTEAGVFDTPDDVFYLLVDEIDALPAD-
Rv2047c|M.tuberculosis_H37Rv RRDRMVRAIWVLRALLREYGRRLTEAGVFDTPDDVFYLLVDEIDALPAD-
MMAR_3024|M.marinum_M RRDKMVRAIWVLRALLREHGRRLAEAGVLHASDDVFYLLVDELDALPAD-
MUL_2265|M.ulcerans_Agy99 RRDKMVRAIWVLRALLREHGRRLAEAGVLHASDDVFYLLVDEVDALPAD-
MAV_2451|M.avium_104 RRDKVVRANWVLRALLREYGRRLTHAGVFGSADDVFYLLVDELDALPAD-
MAB_0994|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01942|M.leprae_Br4923 --------------------------------------------------
Mvan_2632|M.vanbaalenii_PYR-1 PKFDMVRAMALGRRTLRRCGAALVERGLLDDADDVFFLDGADVRAALAGR
Mflv_0493|M.gilvum_PYR-GCK TKSRMALMAHLLKRGYRHLGEVLHEAGRLPDADLVFFFDRRELPLVVSGD
TH_4230|M.thermoresistible__bu ERHYVDRATMSKKRAFLELGRRLLARDLIERLDDVYFLTKDELYELMAER
MSMEG_3934|M.smegmatis_MC2_155 TPNIHLMIPFVRTRWELEECLALVDASPLRRHRNLHRWVMAEVPSVVHWL
Mb2073c|M.bovis_AF2122/97 ----VSGLVARRRAEQRRLAGIV---PPTVFSGSWEPSP--SSAAALAAG
Rv2047c|M.tuberculosis_H37Rv ----VSGLVARRRAEQRRLAGIV---PPTVFSGSWEPSP--SSAAALAAG
MMAR_3024|M.marinum_M ----VAELVARRRAEQRRLTAVV---PPTVFSGKWEPST--ASAAALTAG
MUL_2265|M.ulcerans_Agy99 ----VAELVARRRAEQRRLTAVV---PPTVFSGKWEPST--ASAAALTAE
MAV_2451|M.avium_104 ----VAAVVARRRAEHRRLAGIA---PPTVFSGSWQPTA--TSVPALAGG
MAB_0994|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01942|M.leprae_Br4923 --------------------------------------------------
Mvan_2632|M.vanbaalenii_PYR-1 ACDLRARAAADHRSFRRELRRRR---VPRVLTSEGEAVYGFDTATPGAET
Mflv_0493|M.gilvum_PYR-GCK ----DVTELVHRARQRREALPFQ---AALEFGDVSVGRPTPIVRAAVSGD
TH_4230|M.thermoresistible__bu APQALVRAKIAGRRKQFEAFDRKDAIPPMYLQHGREWIDPTEISGGDVDP
MSMEG_3934|M.smegmatis_MC2_155 P--------------EYVGMG---------------------IDGVSIGS
Mb2073c|M.bovis_AF2122/97 DTLRGVGVCGGRVRGRVRIVRPETID-DLQPGEILVAEVTDVGYTAAFC-
Rv2047c|M.tuberculosis_H37Rv DTLRGVGVCGGRVRGRVRIVRPETID-DLQPGEILVAEVTDVGYTAAFC-
MMAR_3024|M.marinum_M GTLRGVGVCGGRVRGRVRIVRPETID-ELEPGEILVAEVTDVGYTAAFC-
MUL_2265|M.ulcerans_Agy99 GTLRGVGVCGGRVRGRVRIVRPETID-ELEPGEILVAEVTDVGYTAAFC-
MAV_2451|M.avium_104 GTLRGVGVCGGRVRGRVRIVRPETID-DLQPGEILVAEATDVGYTAAFC-
MAB_0994|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01942|M.leprae_Br4923 --------------------------------------------------
Mvan_2632|M.vanbaalenii_PYR-1 DVLIGTALSPGVHVGTVRVLDSPVGA-NLQPGEVIVAASTDPGWTPLFL-
Mflv_0493|M.gilvum_PYR-GCK GVVAGRPAGHGSVEGVVRVARSVVEARDLQPGEILVAPVTDVGWTPYFA-
TH_4230|M.thermoresistible__bu RALQGLPTSPGTVEGRARVVRELDGIGCLEKGDILITNSTDPGWTPVFA-
MSMEG_3934|M.smegmatis_MC2_155 NDLTQLMLGVDRDSETCAELFDESDAAVLDAISRIISTANRLGITSSLCG
Mb2073c|M.bovis_AF2122/97 YAAAVVTELGGPMSHAAVVAREFGFPCVVDAQGATRFLPPGALVEVDGAT
Rv2047c|M.tuberculosis_H37Rv YAAAVVTELGGPMSHAAVVAREFGFPCVVDAQGATRFLPPGALVEVDGAT
MMAR_3024|M.marinum_M YAAAVVTELGGPMSHAAVVAREFGFPCVVDAQGATRFLPPGALIEVDGTT
MUL_2265|M.ulcerans_Agy99 YAAAVVTELGGPMSHAAVVAREFGFPCVVDAQGATRFLPPGALIEVDGTT
MAV_2451|M.avium_104 YAAAVVTELGGPMSHAAVVAREFGFPCVVDVQGATKSLPPGALVEVDGAT
MAB_0994|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01942|M.leprae_Br4923 --------------------------------------------------
Mvan_2632|M.vanbaalenii_PYR-1 LAGALVMEVGGVMSHGALVAREYGLPAVAGIGNAMTRLRSGQRVRVDGTA
Mflv_0493|M.gilvum_PYR-GCK VIAALVTDIGSSVSHGAVVAREYGLPCVVNTLVGTQVLRTGDRVRVDGDR
TH_4230|M.thermoresistible__bu IIGGLILETGGMLAHGSCLSREYGLPAVTVAN-ACSHIADGAHIRVDGHT
MSMEG_3934|M.smegmatis_MC2_155 QAPSTRPEFAEHLVRMGITSVSVNPDAAGAARRAVAAAERRLLLDSVRHP
Mb2073c|M.bovis_AF2122/97 GEIHVVELASEDGPALPGSDLSR---------------------
Rv2047c|M.tuberculosis_H37Rv GEIHVVELASEDGPALPGSDLSR---------------------
MMAR_3024|M.marinum_M GEIQVLELAAEGDSSVTQSDPADLA-------------------
MUL_2265|M.ulcerans_Agy99 GEIQVLELAAEGDSSVTQSDPADLA-------------------
MAV_2451|M.avium_104 GEIRVLELASEPATGGG---------------------------
MAB_0994|M.abscessus_ATCC_1997 --------------------------------------------
MLBr_01942|M.leprae_Br4923 --------------------------------------------
Mvan_2632|M.vanbaalenii_PYR-1 GSVTLLDSVAPDGAAEDPAPTADRAAGSGPRPAPRPRPVSPDSR
Mflv_0493|M.gilvum_PYR-GCK GLVTVLDSP-----------------------------------
TH_4230|M.thermoresistible__bu GMVSVLDDELAAAR------------------------------
MSMEG_3934|M.smegmatis_MC2_155 RHAPTASPRNPL--------------------------------