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M. ulcerans Agy99 MUL_2265 (-)

annotation: hypothetical protein MUL_2265
coordinates: 2518555 - 2521215
length: 886

RVAVTGAGGVLGRGLASRLLSQGHEVVGMSRRRPDSWPSQADFVAGDIRDAAAVRRAITGADVVAHCAWA
RNPGPDGRISQQINIDGTRNVLDAMAACGTGRIVFPSSPHVYRPGLPMPATEHGAVAPASAEGRHKAGVE
QMLQESGAQWVAVRSALIVGRNIDNWVRRLFALPAFPDGSADDVLQVVHLDDVLRLLTRAVSDVGAGTGP
VNLAAPGLPTLREIATALRRPILPVGAALRRIGSVAEFQLVQGVPVMDTARLHDEWKFQPAFTAEESVED
FALAVRGRVSLGRRVVSLPWRLANIQDLPAIDASAQDGVVPRLAGPEGVNGEFDTPIDPRFPTFLATNLS
EALPGPFSPSSASVTVRGLRAGGVGIAERLRPGGVIQREIAMRTVAVFAHRLYGAITSAHFMAETVPFAK
PAMIVSNSGFFGPSMGSLPIFGEERPPAESSFVRRQLCTVRNIGVFGVNLVGLSAGSALDTNDFIADVDR
LEQLAGGDVTTLDDRRLLSLILLARDHVVHGWVLASGSFMLCAAFNVLLRAVSGRDTAPAAGPELVSARS
VEAVQRLVDAARHDEAVIRLLSEPGDRLGKLAVAAPHFYDAVRQELSLIGHRGPAEVEMMSTSYADNPEL
LVGMVAKTLSTSSVPQPPQPSIPLQAKPIAVLAARQLRDREARRDKMVRAIWVLRALLREHGRRLAEAGV
LHASDDVFYLLVDEVDALPADVAELVARRRAEQRRLTAVVPPTVFSGKWEPSTASAAALTAEGTLRGVGV
CGGRVRGRVRIVRPETIDELEPGEILVAEVTDVGYTAAFCYAAAVVTELGGPMSHAAVVAREFGFPCVVD
AQGATRFLPPGALIEVDGTTGEIQVLELAAEGDSSVTQSDPADLA*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_2265--100% (886)hypothetical protein MUL_2265
M. ulcerans Agy99MUL_3007-7e-6228.72% (773) hypothetical protein MUL_3007
M. ulcerans Agy99MUL_2058-1e-1428.23% (333) hypothetical protein MUL_2058

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2073c-0.075.40% (882) hypothetical protein Mb2073c
M. gilvum PYR-GCKMflv_0493-7e-4030.81% (581) pyruvate, water dikinase
M. tuberculosis H37RvRv2047c-0.075.40% (882) hypothetical protein Rv2047c
M. leprae Br4923MLBr_00955ppdK7e-1130.11% (186) pyruvate phosphate dikinase
M. abscessus ATCC 19977MAB_2971c-5e-1433.53% (173) putative oxidoreductase
M. marinum MMMAR_3024-0.098.98% (886) hypothetical protein MMAR_3024
M. avium 104MAV_2451-0.072.36% (872) hypothetical protein MAV_2451
M. smegmatis MC2 155MSMEG_3934-3e-1941.67% (132) phosphoenolpyruvate synthase
M. thermoresistible (build 8)TH_4555-2e-2529.07% (313) PUTATIVE putative phosphoenolpyruvate synthase
M. vanbaalenii PYR-1Mvan_1818-1e-3126.80% (821) pyruvate, water dikinase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0493|M.gilvum_PYR-GCK          -------------------MFDASSRIVDLADVLDDSFGGKALGLAELTR
Mvan_1818|M.vanbaalenii_PYR-1       ----------------------MAPATIEFDDVTDDRFGGKAAGLAELRR
MUL_2265|M.ulcerans_Agy99           MRVAVTGAGGVLGRGLASRLLSQGHEVVGMSRRRPDSWPSQADFVAGDIR
MMAR_3024|M.marinum_M               MRVAVTGAGGVLGRGLASRLLSQGHEVVGMSRRRPDSWPSQADFVAGDIR
Mb2073c|M.bovis_AF2122/97           MRIAVTGASGVLGRGLTARLLSQGHEVVGIARHRPDSWPSSADFIAADIR
Rv2047c|M.tuberculosis_H37Rv        MRIAVTGASGVLGRGLTARLLSQGHEVVGIARHRPDSWPSSADFIAADIR
MAV_2451|M.avium_104                MRIAVTGASGVLGRGLAARLLSKGHDVVGIARHRPDSWSSAADFIEADIR
TH_4555|M.thermoresistible__bu      -MMTDMSAVTSPNTVEAEHTVSNVIRFADPGATDPRLVGGKGMNLGELVA
MAB_2971c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_3934|M.smegmatis_MC2_155      ---------------MDIMSDRYVRTLDILTIADAEEAGGKGANLGELVA
MLBr_00955|M.leprae_Br4923          ------------------MPGQSHKEPHRRATSTPRSLKQATSELRWALS
                                                                                      

Mflv_0493|M.gilvum_PYR-GCK          LGLPVPPGFVIADASGTS----------------LGDAVTERFSRMRAAG
Mvan_1818|M.vanbaalenii_PYR-1       IGLSVPVGFVIADASAHG----------------ALDAAVDRFCQMAAEG
MUL_2265|M.ulcerans_Agy99           DAAAVRRAITGADVVAHCAWARNPGPDGRISQQINIDGTRNVLDAMAACG
MMAR_3024|M.marinum_M               DAAAVRRAITGADVVAHCAWARNPGPDGRISQQINIDGTRNVLDAMAACG
Mb2073c|M.bovis_AF2122/97           DATAVESAMTGADVVAHCAWVRGR------NDHINIDGTANVLKAMAETG
Rv2047c|M.tuberculosis_H37Rv        DATAVESAMTGADVVAHCAWVRGR------NDHINIDGTANVLKAMAETG
MAV_2451|M.avium_104                DAAAVNRAVTSADVVAHFAWTHDT--QERTGSQVNIAGTANVLAAMAETS
TH_4555|M.thermoresistible__bu      AGFRVPNGFTVSTEAYAATLADSGAADRIFELLKGLDVADLARLESTAAA
MAB_2971c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_3934|M.smegmatis_MC2_155      ADLPVPHGFVVMRSAYLDSVRMGGVEAELAALHTEALTHAADTARLSELC
MLBr_00955|M.leprae_Br4923          LAAPESPAFMRHLLGNAH----------------DKVDITTSSEHVAAFT
                                                                                      

Mflv_0493|M.gilvum_PYR-GCK          QTPVAVRSS--------------------------------AAGEDGAEH
Mvan_1818|M.vanbaalenii_PYR-1       VTPVAVRSS--------------------------------AVGEDGEDQ
MUL_2265|M.ulcerans_Agy99           TGRIVFPSSPHVYRPGLPMPATEHGAVAPASAEGRHKAGVEQMLQESGAQ
MMAR_3024|M.marinum_M               TGRIVFPSSPHVYRPGVPMPATEHGAVAPASAEGRHKAGVEQMLQESGAQ
Mb2073c|M.bovis_AF2122/97           TGRIVFTSS-------------------------GHQPRVEQMLADCGLE
Rv2047c|M.tuberculosis_H37Rv        TGRIVFTSS-------------------------GHQPRVEQMLADCGLE
MAV_2451|M.avium_104                ARRIVFPSSPHVYGGG-DTPRSEAEAPAPSAADAVQQARVEEMLVASGLE
TH_4555|M.thermoresistible__bu      IRDVVTAVELP-----DKLAHDIERAYTELGADVYVAVRSSGTAEDTAEA
MAB_2971c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_3934|M.smegmatis_MC2_155      RRMQSLVNKAG---LSPSVRDATLAAYRALGTDVVVAVRSSATGEDGRDA
MLBr_00955|M.leprae_Br4923          EHAIVLLNG-----------------------------------NAHQTR
                                                                                      

Mflv_0493|M.gilvum_PYR-GCK          SFAGQYDTVLG---VGSVDELTAAVEKCVRSAGSER-AAAYQDGGAAARM
Mvan_1818|M.vanbaalenii_PYR-1       SFAGQYDTVLG---VASVDDFTAAVRRCAGSVASQR-ASSYS-GHSPATM
MUL_2265|M.ulcerans_Agy99           WVAVRSALIVGRNIDNWVRRLFALPAFPDGSADDVL-QVVHLDDVLRLLT
MMAR_3024|M.marinum_M               WVAVRSALIVGRNIDNWVRRLFALPAFPDGSADDVL-QVVHLDDVLRLLT
Mb2073c|M.bovis_AF2122/97           WVAVRCALIFGRNVDNWVQRLFALPVLPAGYADRVV-QVVHSDDAQRLLV
Rv2047c|M.tuberculosis_H37Rv        WVAVRCALIFGRNVDNWVQRLFALPVLPAGYADRVV-QVVHSDDAQRLLV
MAV_2451|M.avium_104                SVTIRCALVVGRNVDNWVRRVLALPAFPGGTVDRPI-QLVHLDDALRLLE
TH_4555|M.thermoresistible__bu      SFAGMHDTYLDIRGTGEVLDAVRRCWASMWTARAVAYREEHGFDHREAKI
MAB_2971c|M.abscessus_ATCC_199      ------MRVLVTGGTGFVGGWTAKAMAEAG-------------HKVRFLV
MSMEG_3934|M.smegmatis_MC2_155      SFAGMNRTITNVMGEVALLDAVTQCWMSLFSPRVIT-YRASRGFTAAPAM
MLBr_00955|M.leprae_Br4923          ELLGGKGYNINAMRRHQLAVPPAFCITTEVGVRYLA--------APTPTM
                                                     :                                

Mflv_0493|M.gilvum_PYR-GCK          HLVVQQMVDARAAGVVFTADPTSGRRDLLVIDAVRGLGESLVDGSTASDH
Mvan_1818|M.vanbaalenii_PYR-1       HVVVQQMVDARAAGVVFTADPATGRRDLMVIDAIAGLGEALVDGSASPDH
MUL_2265|M.ulcerans_Agy99           RAVSDVGAGTGPVNLAAPGLPTLREIATALRRPILPVG-AALRRIGSVAE
MMAR_3024|M.marinum_M               RAVSDVGAGTGPVNLAAPGLPTLREIAMALRRPILPVG-AVLRRIGSVAE
Mb2073c|M.bovis_AF2122/97           RALLDTVIDSGPVNLAAPGELTFRRIAAALGRPMVPIGSPVLRRVTSFAE
Rv2047c|M.tuberculosis_H37Rv        RALLDTVIDSGPVNLAAPGELTFRRIAAALGRPMVPIGSPVLRRVTSFAE
MAV_2451|M.avium_104                SAVLSHEIPSGTVNLAAPGTTTFRRIAATLRRPVLRLG------RPAPAE
TH_4555|M.thermoresistible__bu      AVVVQTMAEADVSGVMYTANPLNNRTDEIVINSAYGLGESIVSGAINPDE
MAB_2971c|M.abscessus_ATCC_199      RKEARLHTTVATLGVDVSDYAVG---------------------------
MSMEG_3934|M.smegmatis_MC2_155      AVVVQQMLSADRAGVAFTSDPSTGDADHIVIEAAFGQGEVVVSGKVEPDT
MLBr_00955|M.leprae_Br4923          EAIWNDVLDQMRWLEAETSRTFGWGPRPLLVSIRSG--------------
                                                     .                                

Mflv_0493|M.gilvum_PYR-GCK          FVLTHAG-----DTVTTEAS----------------------SQPALADD
Mvan_1818|M.vanbaalenii_PYR-1       VVLNADG-----STAVREVG----------------------TAPVLSSD
MUL_2265|M.ulcerans_Agy99           FQLVQGVPVMDTARLHDEWK----------------------FQPAFTAE
MMAR_3024|M.marinum_M               FQLVQGVPVMDTARLHDEWK----------------------FQPAFTAE
Mb2073c|M.bovis_AF2122/97           LELLHSAPLMDVTLLRDRWG----------------------FQPAWNAE
Rv2047c|M.tuberculosis_H37Rv        LELLHSAPLMDVTLLRDRWG----------------------FQPAWNAE
MAV_2451|M.avium_104                LEPVLSAPLMDTALLHERWG----------------------FRPAWQCG
TH_4555|M.thermoresistible__bu      FTVDLGTLKIKQANVGNKKEKIVRAPDKPSGTVTLAVSEEDAGRLSLTDE
MAB_2971c|M.abscessus_ATCC_199      -------------DITDRAS----------------------VEAALDGC
MSMEG_3934|M.smegmatis_MC2_155      YVIDKRTLEVRDVRIGFKAIKIVRGDDGADSMVQLERSQ---AEARVLDD
MLBr_00955|M.leprae_Br4923          -------------AVQSMPG---------------------------MMD
                                                                                      

Mflv_0493|M.gilvum_PYR-GCK          EIDRIRTGALLAAAHWG-RPLDLEWAIDRDGLLWWLQARPITTLP-----
Mvan_1818|M.vanbaalenii_PYR-1       DVAEIRSGALRAARHWG-RPLDLEWAIDGTGKLWWLQARPITTLP-----
MUL_2265|M.ulcerans_Agy99           ESVEDFALAVRGRVSLGRRVVSLPWRLANIQDLPAIDASAQDGVVPRLAG
MMAR_3024|M.marinum_M               ESVEDFALAVRGRVSLGRRVVSLPWRLANIQDLPAVDAPAQDGVVPRLAG
Mb2073c|M.bovis_AF2122/97           ECLEDFTLAVRGRIGLGKRTFSLPWRLANIQDLPAVDSPADDGVAPRLAG
Rv2047c|M.tuberculosis_H37Rv        ECLEDFTLAVRGRIGLGKRTFSLPWRLANIQDLPAVDSPADDGVAPRLAG
MAV_2451|M.avium_104                ECVEDMALAVRGRVTVGRRVVSLPWRLANVADLPAVDAPAQDGVVPVPAG
TH_4555|M.thermoresistible__bu      QVAELAALGRQVMDHYGGLPQDIEWACVD-GEFFLLQTRPITGAKFTWP-
MAB_2971c|M.abscessus_ATCC_199      DAVVHSAAMVSTDPAEADRMMAINLEGTRNVLGAAVDR------------
MSMEG_3934|M.smegmatis_MC2_155      DALRKIATLAVATETHNGCPQDIEWVIAD-GAVWLVQARPITTLG-----
MLBr_00955|M.leprae_Br4923          TILNLGINDPVEQALAAASPSPIPQTFARDTRLRFIRTYRRIVDP-----
                                                          :            :              

Mflv_0493|M.gilvum_PYR-GCK          --GDPNEMDTPVTGPTHVYTRCNIGEMMPGAFCPLTASVSGHAIDY-AMQ
Mvan_1818|M.vanbaalenii_PYR-1       --GDLNEMDSPVAGSDHVYTRCNIGEMMPGAFCPLTASVSGYAIDY-AMQ
MUL_2265|M.ulcerans_Agy99           PEGVNGEFDTPIDPRFPTFLATNLSEALPGPFSPSSASVTVRGLRAGGVG
MMAR_3024|M.marinum_M               PEGVNGEFDTPIDPRFPTFLATNLSEALPGPFSPSSASVTVRGLRAGGVG
Mb2073c|M.bovis_AF2122/97           PEGANGEFDTPIDPRFPTYLATNLSEALPGPFSPSSASVTVRGLRAGGVG
Rv2047c|M.tuberculosis_H37Rv        PEGANGEFDTPIDPRFPTYLATNLSEALPGPFSPSSASVTVRGLRAGGVG
MAV_2451|M.avium_104                PEGVNGEFDTPIDPRFPTFLATNLSEALPGPFSPSSASATVRGVRAGGVT
TH_4555|M.thermoresistible__bu      --EGFNDWQNGPEDPDTLWTFKYAEQYWTGGITPLFFSVRARETQVGYDR
MAB_2971c|M.abscessus_ATCC_199      -------------GLDPIVHVSSITALFRPGLETFAADLPAAGGSDGYGQ
MSMEG_3934|M.smegmatis_MC2_155      ----SAGSTAGDEPSVLIRGLPAAPGVASGRVRVLLAPDDGDKLTDGEIL
MLBr_00955|M.leprae_Br4923          --------LNPPPANTYDQLRAAIESIFSSWNSPRAVAYRTHYGLDDQSG
                                                                                      

Mflv_0493|M.gilvum_PYR-GCK          MVQVAGGVQERYEDRARQVGYFFGHMFLNMTEGTALSSGILG-NSLEQFS
Mvan_1818|M.vanbaalenii_PYR-1       MTQVVARAQPRYEKPWLQVGYFYGHMFLNLTEGTALSSGILG-NSREQFS
MUL_2265|M.ulcerans_Agy99           IAERLRPGGVIQREIAMRTVAVFAHRLYGAITSAHFMAETVP-FAKPAMI
MMAR_3024|M.marinum_M               IAERLRPGGVIQREIAMRTVAVFAHRLYGAITSAHFMAETVP-FAKPAMI
Mb2073c|M.bovis_AF2122/97           IAERLRPSGVIQREIAMRTVAVFAHRLYGAITSAHFMAATVP-FAKPATI
Rv2047c|M.tuberculosis_H37Rv        IAERLRPSGVIQREIAMRTVAVFAHRLYGAITSAHFMAATVP-FAKPATI
MAV_2451|M.avium_104                IAERLRPGGLVQREIALRTVGVFAHRLYGAITSAHFMAETVP-FAKPSMI
TH_4555|M.thermoresistible__bu      MNARAGFQDLLGQRLYKDK---YGTVYWNVDMDEKRLRYVLPRFARPAGA
MAB_2971c|M.abscessus_ATCC_199      SKARVELYVRALQDSGAPVTITYPGMVLGPPVGDQFGEAAEG--------
MSMEG_3934|M.smegmatis_MC2_155      VAPTTNPDWLPTIRRAAALVTETGGMTCHAAIVARELGVPCVVGARSATV
MLBr_00955|M.leprae_Br4923          TAVIVQAMVFGNQGAYSGAGTLFSRNPITRESKLFGEWLPGGQGDDVVSG
                                                                                      

Mflv_0493|M.gilvum_PYR-GCK          LSVCGRVIDELEPGPPKPFVRKLINTVRLSTFALSSAPAIRRLPQTIAAF
Mvan_1818|M.vanbaalenii_PYR-1       MSICGRVVDELEAKPPRPFARKLVNTVRLTSHALSAGPAIRRLADQIAGW
MUL_2265|M.ulcerans_Agy99           VSNSGFFGPSMGSLPIFGEERPPAESSFVR-RQLCTVRNIGVFGVNLVGL
MMAR_3024|M.marinum_M               VSNSGFFGPSMGSLPIFGEERPPAESSFVR-RQLRTVRNIGVFGVNLVGL
Mb2073c|M.bovis_AF2122/97           VSNSGFFGPSMASLPIFGAQRPPSESSRAR-RWLRTLRNIGVFGVNLVGL
Rv2047c|M.tuberculosis_H37Rv        VSNSGFFGPSMASLPIFGAQRPPSESSRAR-RWLRTLRNIGVFGVNLVGL
MAV_2451|M.avium_104                VSNSGFFGPSMASLPVFGEQRP-AETGWAR-RLLRNTRNIGVFGVNLVGL
TH_4555|M.thermoresistible__bu      NVVPADMQEQMFAEPLDVVRWLKAMISFSVSPIYSLSRWKKVIREDYLFN
MAB_2971c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_3934|M.smegmatis_MC2_155      ALAVGSMVTVDGTRGEVTTGRLPETVRTTTTPQEPAPHITG---------
MLBr_00955|M.leprae_Br4923          LVEVQPITSLRDEQP-----------------------------------
                                                                                      

Mflv_0493|M.gilvum_PYR-GCK          PPITSRDPAVVLRHLE-------AGVDIYREVTLIHVRSSSRSAVAANVL
Mvan_1818|M.vanbaalenii_PYR-1       PIPSHEDARLVLQQLE-------SGVQLYCDVTLTHVRSSSRAAVAANIL
MUL_2265|M.ulcerans_Agy99           SAGSALDTNDFIADVDRLEQLAGGDVTTLDDRRLLSLILLARDHVVHGWV
MMAR_3024|M.marinum_M               SAGSALDTNDFIADVDRLEQLAGGDVTTLDDRRLLSLILLARDHVVHGWV
Mb2073c|M.bovis_AF2122/97           SAGSPRDTDAYVADVDRLERLAFDNLATHDDRRLLSLILLARDHVVHGWV
Rv2047c|M.tuberculosis_H37Rv        SAGSPRDTDAYVADVDRLERLAFDNLATHDDRRLLSLILLARDHVVHGWV
MAV_2451|M.avium_104                SSGAARDTDDFIADVDRLERLAG-DAAELDERRLLSLIALARDQVVHGWV
TH_4555|M.thermoresistible__bu      EAAVAKANGLSDAELRALSDDELYRYQRDLQEYAIDFMDPLWFGAYTAMS
MAB_2971c|M.abscessus_ATCC_199      ---------------------------------VRWVLLTRSVPGRSAAW
MSMEG_3934|M.smegmatis_MC2_155      -------------------------EATGTKVYVNLAMPDSAEAVAAQDV
MLBr_00955|M.leprae_Br4923          ---------------------------TVYDELVDTAGRLERLGSDVQEI
                                                                                      

Mflv_0493|M.gilvum_PYR-GCK          ESHLVRRAAKRGASDTAGSAEAIRLMTGAG-VESALMVEELTAVVSMLRR
Mvan_1818|M.vanbaalenii_PYR-1       ESTLVRQAVKNGRSEEEGQAEAARLMAGASDVESAMMLDQLQSVVRAIAA
MUL_2265|M.ulcerans_Agy99           LASGSFMLCAAFNVLLRAVSGRDTAPAAGPELVSARSVEAVQRLVDAARH
MMAR_3024|M.marinum_M               LASGSFMLCAAFNVLLRAVSGRDTAPAAGPELVSARSVEAVQRLVAAARH
Mb2073c|M.bovis_AF2122/97           LASGSFMLCAAFNVLLRGLCGRDTAPAAGPELVSARSVEAVQRLVAAARR
Rv2047c|M.tuberculosis_H37Rv        LASGSFMLCAAFNVLLRGLCGRDTAPAAGPELVSARSVEAVQRLVAAARR
MAV_2451|M.avium_104                LASASFMLCAAFNVLLRAVCGRDTSAPAGPELVSARSVEAMQRLVVAAQR
TH_4555|M.thermoresistible__bu      MFFSLHAALLAKYYTGTNELLGQDLISGLPTTLQALENRAFFELTSMIRH
MAB_2971c|M.abscessus_ATCC_199      LVVDVRDLAALHTALLEPSRGPRRYTAGGHRLEVGELVDLLTEAAGSAVL
MSMEG_3934|M.smegmatis_MC2_155      DGVGLLRAEFMLTEALAGRHPRDLITKGEQDTLVDAMAAAVTRIGTAFAP
MLBr_00955|M.leprae_Br4923          EFTTEDSKLWLLQTRVAERSAQVAVRLALQLWQEGLIDDAEALRRVTPVH
                                                               .                      

Mflv_0493|M.gilvum_PYR-GCK          DGDAAARFLAAPAGEAVTRLRAAET--PSGAALRTFLDRHGHRGYRELCM
Mvan_1818|M.vanbaalenii_PYR-1       DSGVATRFLAAAPDVAVVELQRADN--ASGEALRQFLLRHGHRGYRELCM
MUL_2265|M.ulcerans_Agy99           DEAVIR--LLSEPGDRLGKLAVAAP--HFYDAVRQELSLIGHRGPAEVEM
MMAR_3024|M.marinum_M               DEAVIR--LLSEPGDRLGKLAVAAP--HFYDAVRQELSLIGHRGPAEVEM
Mb2073c|M.bovis_AF2122/97           DPVVIR--LLAEPGERLDKLAVEAP--EFHSAVLAELTLIGHRGPAEVEM
Rv2047c|M.tuberculosis_H37Rv        DPVVIR--LLAEPGERLDKLAVEAP--EFHSAVLAELTLIGHRGPAEVEM
MAV_2451|M.avium_104                DPNVAR--VLTEPGERLDKLAVDAP--EFHAAVLAELALIGHRGPAELEM
TH_4555|M.thermoresistible__bu      SKVLSDAFEKHQGAAFFAELENSDEGREFLEKYREFLAEHGHRGHPDRDL
MAB_2971c|M.abscessus_ATCC_199      AVPVPDS-LLRAAGTVMDQIGRYVP-------WETPMTEAGMQYYTQMPA
MSMEG_3934|M.smegmatis_MC2_155      RPVIYR--AMDFRTNEFRGLAGGEQ-----FEPVEHNPMIGYRGCYRYIK
MLBr_00955|M.leprae_Br4923          VETVLLPVLQPENHLSATLLAKGTP---------TCPGVISGKAYTEVDE
                                                       :                    . :       

Mflv_0493|M.gilvum_PYR-GCK          RDPSWADDPDGLGAMMQVMLRGAAPENPAATAPSD---------------
Mvan_1818|M.vanbaalenii_PYR-1       RDPSWAQDAGGLGAMMQVMVRAASSDRQPAHSPTE---------------
MUL_2265|M.ulcerans_Agy99           MSTSYADNPELLVGMVAKTLSTSS-----VPQPPQ---------------
MMAR_3024|M.marinum_M               MSTSYADNPELLVGMVAKTLSTSS-----VPQPPQ---------------
Mb2073c|M.bovis_AF2122/97           AATSYADNPELLVRMVAKTLRAVP-----APQPPT---------------
Rv2047c|M.tuberculosis_H37Rv        AATSYADNPELLVRMVAKTLRAVP-----APQPPT---------------
MAV_2451|M.avium_104                LSTSYADDPELLVRMVAKAMAATA-----APPPQH---------------
TH_4555|M.thermoresistible__bu      IFKRRADDPAVDYEAFKVQLQAPEATPPIELEERVRARREAAEAEVIENL
MAB_2971c|M.abscessus_ATCC_199      SDDTPSE------RELGITYRDPR--------------------------
MSMEG_3934|M.smegmatis_MC2_155      EPD-----------------------------------------------
MLBr_00955|M.leprae_Br4923          ALD-----------------------------------------------
                                                                                      

Mflv_0493|M.gilvum_PYR-GCK          ------PAQSRTLRVLARLAQAGARGREETKSRMALMAHLLKRGYRHLGE
Mvan_1818|M.vanbaalenii_PYR-1       ------APTSPAIRFLARLAQGGARGREETKSKMALMAHALKRGYRHLGE
MUL_2265|M.ulcerans_Agy99           ------PSIPLQAKPIAVLAARQLRDREARRDKMVRAIWVLRALLREHGR
MMAR_3024|M.marinum_M               ------PSIPLQAKPIAVLAARQLRDREARRDKMVRAIWVLRALLREHGR
Mb2073c|M.bovis_AF2122/97           ------PVIPLRAKPVALLAARQLRDREVRRDRMVRAIWVLRALLREYGR
Rv2047c|M.tuberculosis_H37Rv        ------PVIPLRAKPVALLAARQLRDREVRRDRMVRAIWVLRALLREYGR
MAV_2451|M.avium_104                ------PRIPLQAKLIAALTARQLRDREARRDKVVRANWVLRALLREYGR
TH_4555|M.thermoresistible__bu      GRGFLGPVKQQLFKLLQHQIIDFLVLRDDWRHFIDRITYAKRKAFLEVAR
MAB_2971c|M.abscessus_ATCC_199      ----------------ETLADTVVSLRAGRTTSKLWGLWPFSE-------
MSMEG_3934|M.smegmatis_MC2_155      --------------LFALELSALARAREHTPNIHLMIPFVRTRWELEECL
MLBr_00955|M.leprae_Br4923          ---------------AAESAEQVILVRDHTRPDDVLGMLASQGVVTEVGG
                                                              *                       

Mflv_0493|M.gilvum_PYR-GCK          VLHEAGRLPDADLVFFFDRRELPLVVSGDDVTELVHRARQRRE---ALPF
Mvan_1818|M.vanbaalenii_PYR-1       VLARSGRLPDADLVFFFDRSELPRVVGDDDISELVQSAVKRRE---ALAY
MUL_2265|M.ulcerans_Agy99           RLAEAGVLHASDDVFYLLVDEVDALP-----ADVAELVARRRA---EQRR
MMAR_3024|M.marinum_M               RLAEAGVLHASDDVFYLLVDELDALP-----ADVAELVARRRA---EQRR
Mb2073c|M.bovis_AF2122/97           RLTEAGVFDTPDDVFYLLVDEIDALP-----ADVSGLVARRRA---EQRR
Rv2047c|M.tuberculosis_H37Rv        RLTEAGVFDTPDDVFYLLVDEIDALP-----ADVSGLVARRRA---EQRR
MAV_2451|M.avium_104                RLTHAGVFGSADDVFYLLVDELDALP-----ADVAAVVARRRA---EHRR
TH_4555|M.thermoresistible__bu      RCVERGRLEKEDDAFFLGETELFEVLNGTAKQPLVQAKIAARRPDFELFE
MAB_2971c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_3934|M.smegmatis_MC2_155      ALVDASPLRRHRNLHRWVMAEVPSVVH-------------------WLPE
MLBr_00955|M.leprae_Br4923          AASHAAVVSR---------------------------------------E
                                                                                      

Mflv_0493|M.gilvum_PYR-GCK          QAALEFGDVSVGRPTPIVR--AAVSGDGVVAGRPAGHGSVEGVVRVARSV
Mvan_1818|M.vanbaalenii_PYR-1       QDSLEFEDVSVGRPRPVVAPPVITSTADQVVGRPASRGTVEGTVRVAKTI
MUL_2265|M.ulcerans_Agy99           LTAVVPPTVFSGKWEPSTASAAALTAEGTLRGVGVCGGRVRGRVRIVR-P
MMAR_3024|M.marinum_M               LTAVVPPTVFSGKWEPSTASAAALTAGGTLRGVGVCGGRVRGRVRIVR-P
Mb2073c|M.bovis_AF2122/97           LAGIVPPTVFSGSWEPSPSSAAALAAGDTLRGVGVCGGRVRGRVRIVR-P
Rv2047c|M.tuberculosis_H37Rv        LAGIVPPTVFSGSWEPSPSSAAALAAGDTLRGVGVCGGRVRGRVRIVR-P
MAV_2451|M.avium_104                LAGIAPPTVFSGSWQPTATSVPALAGGGTLRGVGVCGGRVRGRVRIVR-P
TH_4555|M.thermoresistible__bu      SRTFTPPMFMRGETPVDEAAPAAVAGSGAINGVGTSAGQVEGRARVLASM
MAB_2971c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_3934|M.smegmatis_MC2_155      YVGMGIDGVSIGSND-LTQLMLGVDRDSETCAELFDESDAAVLDAISRII
MLBr_00955|M.leprae_Br4923          LSRVAVVGCGQGTAVSLAGKQITVDGD---------KGEVRQGNLTLSAW
                                                                                      

Mflv_0493|M.gilvum_PYR-GCK          VEARDLQPGEILVAPVTDVGWTPYFAVIAALVTDIGSSVSHGAVVAREYG
Mvan_1818|M.vanbaalenii_PYR-1       QDARDVQRGEILVAPVTDVGWTPYFTVIAALITDIGSSVSHGAVVAREYG
MUL_2265|M.ulcerans_Agy99           ETIDELEPGEILVAEVTDVGYTAAFCYAAAVVTELGGPMSHAAVVAREFG
MMAR_3024|M.marinum_M               ETIDELEPGEILVAEVTDVGYTAAFCYAAAVVTELGGPMSHAAVVAREFG
Mb2073c|M.bovis_AF2122/97           ETIDDLQPGEILVAEVTDVGYTAAFCYAAAVVTELGGPMSHAAVVAREFG
Rv2047c|M.tuberculosis_H37Rv        ETIDDLQPGEILVAEVTDVGYTAAFCYAAAVVTELGGPMSHAAVVAREFG
MAV_2451|M.avium_104                ETIDDLQPGEILVAEATDVGYTAAFCYAAAVVTELGGPMSHAAVVAREFG
TH_4555|M.thermoresistible__bu      TEIGTLEQGDVLVCNATDPGWSPVFGVISGLIIETGGMLAHGACLSREHG
MAB_2971c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_3934|M.smegmatis_MC2_155      STANRLGITSSLCGQAPSTRPEFAEHLVRMGITSVSVNPDAAGAARRAVA
MLBr_00955|M.leprae_Br4923          SENETPELRELADIARRISPLRVHMTEDHTRLDDSSDTAVRLAINTGHAD
                                                                                      

Mflv_0493|M.gilvum_PYR-GCK          LPCVVNTLVGTQVLRTGDRVRVDGDRGLVTVLDSP---------------
Mvan_1818|M.vanbaalenii_PYR-1       LPCVVNTLVGTQVLRTGDRVRVDGDRGVVTRLG-----------------
MUL_2265|M.ulcerans_Agy99           FPCVVDAQGATRFLPPGALIEVDGTTGEIQVLELAAEGDSSVTQSDPADL
MMAR_3024|M.marinum_M               FPCVVDAQGATRFLPPGALIEVDGTTGEIQVLELAAEGDSSVTQSDPADL
Mb2073c|M.bovis_AF2122/97           FPCVVDAQGATRFLPPGALVEVDGATGEIHVVELASEDGPALPGSDLSR-
Rv2047c|M.tuberculosis_H37Rv        FPCVVDAQGATRFLPPGALVEVDGATGEIHVVELASEDGPALPGSDLSR-
MAV_2451|M.avium_104                FPCVVDVQGATKSLPPGALVEVDGATGEIRVLELASEPATGGG-------
TH_4555|M.thermoresistible__bu      IP-AVQIVGATQIIPDGAYVRINGTTGLVEVLEPAPAGAA----------
MAB_2971c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_3934|M.smegmatis_MC2_155      AAERRLLLDSVRHPRHAPTASPRNPL------------------------
MLBr_00955|M.leprae_Br4923          VVSATPLIVMMTTLRLQDSKDSSAKS------------------------
                                                                                      

Mflv_0493|M.gilvum_PYR-GCK          -
Mvan_1818|M.vanbaalenii_PYR-1       -
MUL_2265|M.ulcerans_Agy99           A
MMAR_3024|M.marinum_M               A
Mb2073c|M.bovis_AF2122/97           -
Rv2047c|M.tuberculosis_H37Rv        -
MAV_2451|M.avium_104                -
TH_4555|M.thermoresistible__bu      -
MAB_2971c|M.abscessus_ATCC_199      -
MSMEG_3934|M.smegmatis_MC2_155      -
MLBr_00955|M.leprae_Br4923          -