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VTPRACETRRMLMASMPSASAILTAARTTASRLSPARLIRRHHLPRLAWTRPCGAATIRRRLHFLSHVQK VTGVSMRSHSAPEHNAANALHSMSPPGATWSSVNLAEAVPGVMTPLCASVWVPASELGLREPFVAMGALP VDRGGIPADPAERITNAFFGRMAVRVDFLCEMGDLIPGQSGEALSRDFFGFVPADFRSRPSARRLPFILA RYPRTFAGIGRRIARLRSETDAWWRHEIAAVSRLDLRLAQRLAAEARDRFFTTLAAQAVISATVIQPVQE QLSTLCKAAGVDPAVLLRGASHEENAVLHDLWAASRGALEVDEFVKRHGYHGPGEGELETRVWREDPGAV AGLVRRYSARSDAESPDADAAEHHRRRSEAERDLMSSLGPAARVRARLVLRLARNYIPLRGTGKVAYLQS LDVLRAAARRIGSLLVEQQRLTDPDDAFYLTIDELTGAPLADAATDLRGTISERREIRAHYQSLTLPSAW TGQPEPLAPSASAETSVRSLRGIGACAGVAEGRAVVVTDPTETEIADGDILIAQTTDPSWVSLMFLSAAL VVDIGGLMSHAAVMARELGIPCVMNTGTGTTALRTGDTIRVDGAAGTVEILSRNIQQSSIPERTH
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. avium 104 | MAV_5056 | - | - | 100% (625) | PEP-utilizing protein |
M. avium 104 | MAV_1955 | - | 5e-81 | 32.77% (537) | PEP-utilizing protein |
M. avium 104 | MAV_5062 | - | 2e-61 | 38.07% (394) | pyruvate, water dikinase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2073c | - | 9e-37 | 26.35% (573) | hypothetical protein Mb2073c |
M. gilvum PYR-GCK | Mflv_0493 | - | 1e-33 | 27.45% (561) | pyruvate, water dikinase |
M. tuberculosis H37Rv | Rv2047c | - | 9e-37 | 26.35% (573) | hypothetical protein Rv2047c |
M. leprae Br4923 | MLBr_00955 | ppdK | 8e-11 | 33.58% (137) | pyruvate phosphate dikinase |
M. abscessus ATCC 19977 | - | - | - | - | - |
M. marinum M | MMAR_3024 | - | 1e-35 | 26.87% (562) | hypothetical protein MMAR_3024 |
M. smegmatis MC2 155 | MSMEG_3934 | - | 6e-21 | 36.36% (143) | phosphoenolpyruvate synthase |
M. thermoresistible (build 8) | TH_4555 | - | 1e-23 | 28.90% (301) | PUTATIVE putative phosphoenolpyruvate synthase |
M. ulcerans Agy99 | MUL_2265 | - | 5e-35 | 25.83% (569) | hypothetical protein MUL_2265 |
M. vanbaalenii PYR-1 | Mvan_1818 | - | 1e-34 | 26.64% (563) | pyruvate, water dikinase |
CLUSTAL 2.0.9 multiple sequence alignment Mb2073c|M.bovis_AF2122/97 MRIAVTGASGVLGRGLTARLLSQGHEVVGIARHRPDSWPSSADFIAADIR Rv2047c|M.tuberculosis_H37Rv MRIAVTGASGVLGRGLTARLLSQGHEVVGIARHRPDSWPSSADFIAADIR MMAR_3024|M.marinum_M MRVAVTGAGGVLGRGLASRLLSQGHEVVGMSRRRPDSWPSQADFVAGDIR MUL_2265|M.ulcerans_Agy99 MRVAVTGAGGVLGRGLASRLLSQGHEVVGMSRRRPDSWPSQADFVAGDIR Mflv_0493|M.gilvum_PYR-GCK -------------------MFDASSRIVDLADVLDDSFGGKALGLAELTR Mvan_1818|M.vanbaalenii_PYR-1 ----------------------MAPATIEFDDVTDDRFGGKAAGLAELRR MAV_5056|M.avium_104 ----------------------MTPRACETRRMLMASMPSASAILTAART TH_4555|M.thermoresistible__bu -MMTDMSAVTSPNTVEAEHTVSNVIRFADPGATDPRLVGGKGMNLGELVA MSMEG_3934|M.smegmatis_MC2_155 ---------------MDIMSDRYVRTLDILTIADAEEAGGKGANLGELVA MLBr_00955|M.leprae_Br4923 ------------------MPGQSHKEPHRRATSTPRSLKQATSELRWALS : Mb2073c|M.bovis_AF2122/97 DATAVESAMTGADVVAHCAWVRGR------NDHINIDGTANVLKAMAETG Rv2047c|M.tuberculosis_H37Rv DATAVESAMTGADVVAHCAWVRGR------NDHINIDGTANVLKAMAETG MMAR_3024|M.marinum_M DAAAVRRAITGADVVAHCAWARNPGPDGRISQQINIDGTRNVLDAMAACG MUL_2265|M.ulcerans_Agy99 DAAAVRRAITGADVVAHCAWARNPGPDGRISQQINIDGTRNVLDAMAACG Mflv_0493|M.gilvum_PYR-GCK LGLPVPPGFVIADASGTS----------------LGDAVTERFSRMRAAG Mvan_1818|M.vanbaalenii_PYR-1 IGLSVPVGFVIADASAHG----------------ALDAAVDRFCQMAAEG MAV_5056|M.avium_104 TASRLSPARLIR------------------------RHHLPRLAWTRPCG TH_4555|M.thermoresistible__bu AGFRVPNGFTVSTEAYAATLADSGAADRIFELLKGLDVADLARLESTAAA MSMEG_3934|M.smegmatis_MC2_155 ADLPVPHGFVVMRSAYLDSVRMGGVEAELAALHTEALTHAADTARLSELC MLBr_00955|M.leprae_Br4923 LAAPESPAFMRHLLG---------------------NAHDKVDITTSSEH . Mb2073c|M.bovis_AF2122/97 --TGRIVFTSS-------------------------GHQPRVEQMLADCG Rv2047c|M.tuberculosis_H37Rv --TGRIVFTSS-------------------------GHQPRVEQMLADCG MMAR_3024|M.marinum_M --TGRIVFPSSPHVYRPGVPMPATEHGAVAPASAEGRHKAGVEQMLQESG MUL_2265|M.ulcerans_Agy99 --TGRIVFPSSPHVYRPGLPMPATEHGAVAPASAEGRHKAGVEQMLQESG Mflv_0493|M.gilvum_PYR-GCK --QTPVAVRSS--------------------------------AAGEDGA Mvan_1818|M.vanbaalenii_PYR-1 --VTPVAVRSS--------------------------------AVGEDGE MAV_5056|M.avium_104 --AATIRRRLH--------------------------------------- TH_4555|M.thermoresistible__bu --IRDVVTAVELPDKLAHDIERAYTELG-----ADVYVAVRSSGTAEDTA MSMEG_3934|M.smegmatis_MC2_155 RRMQSLVNKAGLSPSVRDATLAAYRALG-----TDVVVAVRSSATGEDGR MLBr_00955|M.leprae_Br4923 -------------------------------------------------- Mb2073c|M.bovis_AF2122/97 LEWVAVRCALIFGRNVDNWVQRLFALPVLPAGYADRVV-QVVHSDDAQRL Rv2047c|M.tuberculosis_H37Rv LEWVAVRCALIFGRNVDNWVQRLFALPVLPAGYADRVV-QVVHSDDAQRL MMAR_3024|M.marinum_M AQWVAVRSALIVGRNIDNWVRRLFALPAFPDGSADDVL-QVVHLDDVLRL MUL_2265|M.ulcerans_Agy99 AQWVAVRSALIVGRNIDNWVRRLFALPAFPDGSADDVL-QVVHLDDVLRL Mflv_0493|M.gilvum_PYR-GCK EHSFAGQYDTVLG---VGSVDELTAAVEKCVRSAGSER-AAAYQDGGAAA Mvan_1818|M.vanbaalenii_PYR-1 DQSFAGQYDTVLG---VASVDDFTAAVRRCAGSVASQR-ASSYS-GHSPA MAV_5056|M.avium_104 ---------------FLSHVQKVTGVSMRSHSAPEHNA-ANALHSMSPPG TH_4555|M.thermoresistible__bu EASFAGMHDTYLDIRGTGEVLDAVRRCWASMWTARAVAYREEHGFDHREA MSMEG_3934|M.smegmatis_MC2_155 DASFAGMNRTITNVMGEVALLDAVTQCWMSLFSPRVITYRASRGFTAAP- MLBr_00955|M.leprae_Br4923 ---------------VAAFTEHAIVLLNGNAHQTRELLGGKGYNINAMRR Mb2073c|M.bovis_AF2122/97 LVRALLDTVIDSGPVNLAAPGELTFRRIAAALGRPMVPIGSPVLRRVTSF Rv2047c|M.tuberculosis_H37Rv LVRALLDTVIDSGPVNLAAPGELTFRRIAAALGRPMVPIGSPVLRRVTSF MMAR_3024|M.marinum_M LTRAVSDVGAGTGPVNLAAPGLPTLREIAMALRRPILPVG-AVLRRIGSV MUL_2265|M.ulcerans_Agy99 LTRAVSDVGAGTGPVNLAAPGLPTLREIATALRRPILPVG-AALRRIGSV Mflv_0493|M.gilvum_PYR-GCK RMHLVVQQMVDARAAGVVFTADPTSGRRDLLVIDAVRGLGESLVDGSTAS Mvan_1818|M.vanbaalenii_PYR-1 TMHVVVQQMVDARAAGVVFTADPATGRRDLMVIDAIAGLGEALVDGSASP MAV_5056|M.avium_104 ATWSSVNLAEAVPGVMTPLCASVWVPASELGLREPFVAMGALPVDRGG-- TH_4555|M.thermoresistible__bu KIAVVVQTMAEADVSGVMYTANPLNNRTDEIVINSAYGLGESIVSGAINP MSMEG_3934|M.smegmatis_MC2_155 AMAVVVQQMLSADRAGVAFTSDPSTGDADHIVIEAAFGQGEVVVSGKVEP MLBr_00955|M.leprae_Br4923 HQLAVPPAFCITTEVGVRYLAAPTPT------------------------ . Mb2073c|M.bovis_AF2122/97 AELELLHSAPLMDVT----------------------LLRDRWGFQPAWN Rv2047c|M.tuberculosis_H37Rv AELELLHSAPLMDVT----------------------LLRDRWGFQPAWN MMAR_3024|M.marinum_M AEFQLVQGVPVMDTA----------------------RLHDEWKFQPAFT MUL_2265|M.ulcerans_Agy99 AEFQLVQGVPVMDTA----------------------RLHDEWKFQPAFT Mflv_0493|M.gilvum_PYR-GCK DHFVLTHAG-----D----------------------TVTTEASSQPALA Mvan_1818|M.vanbaalenii_PYR-1 DHVVLNADG-----S----------------------TAVREVGTAPVLS MAV_5056|M.avium_104 ---------------------------------------------IPADP TH_4555|M.thermoresistible__bu DEFTVDLGTLKIKQANVGNKKEKIVRAPDKPSGTVTLAVSEEDAGRLSLT MSMEG_3934|M.smegmatis_MC2_155 DTYVID---------------------------------------KRTLE MLBr_00955|M.leprae_Br4923 ---------------------------------------------MEAIW Mb2073c|M.bovis_AF2122/97 AEECLEDFTLAVRGRIGLGKRTFSLPWRLANIQDLPAVDSPADDGVAPRL Rv2047c|M.tuberculosis_H37Rv AEECLEDFTLAVRGRIGLGKRTFSLPWRLANIQDLPAVDSPADDGVAPRL MMAR_3024|M.marinum_M AEESVEDFALAVRGRVSLGRRVVSLPWRLANIQDLPAVDAPAQDGVVPRL MUL_2265|M.ulcerans_Agy99 AEESVEDFALAVRGRVSLGRRVVSLPWRLANIQDLPAIDASAQDGVVPRL Mflv_0493|M.gilvum_PYR-GCK DDEIDRIRTGALLAAAHWG-RPLDLEWAIDRDGLLWWLQARPITTLP--- Mvan_1818|M.vanbaalenii_PYR-1 SDDVAEIRSGALRAARHWG-RPLDLEWAIDGTGKLWWLQARPITTLP--- MAV_5056|M.avium_104 AERITNAFFGRMAVRVDFL------------------------------- TH_4555|M.thermoresistible__bu DEQVAELAALGRQVMDHYGGLPQDIEWACVDGEFFLLQTRPITGAKFTWP MSMEG_3934|M.smegmatis_MC2_155 VRDVRIGFKAIKIVRGDDG------------------------------- MLBr_00955|M.leprae_Br4923 NDVLDQMRWLEAETSRTFG------------------------------- Mb2073c|M.bovis_AF2122/97 AGPEGANGEFDTPIDPRFPTYLATNLSEALPGPFSPSSASVTVRGLRAGG Rv2047c|M.tuberculosis_H37Rv AGPEGANGEFDTPIDPRFPTYLATNLSEALPGPFSPSSASVTVRGLRAGG MMAR_3024|M.marinum_M AGPEGVNGEFDTPIDPRFPTFLATNLSEALPGPFSPSSASVTVRGLRAGG MUL_2265|M.ulcerans_Agy99 AGPEGVNGEFDTPIDPRFPTFLATNLSEALPGPFSPSSASVTVRGLRAGG Mflv_0493|M.gilvum_PYR-GCK ----GDPNEMDTPVTGPTHVYTRCNIGEMMPGAFCPLTASVSGHAIDY-A Mvan_1818|M.vanbaalenii_PYR-1 ----GDLNEMDSPVAGSDHVYTRCNIGEMMPGAFCPLTASVSGYAIDY-A MAV_5056|M.avium_104 -------CEMGDLIPGQSGEALSRDFFGFVPADFR---SRPSARRLPFIL TH_4555|M.thermoresistible__bu ----EGFNDWQNGPEDPDTLWTFKYAEQYWTGGITPLFFSVRARETQVGY MSMEG_3934|M.smegmatis_MC2_155 ------ADSMVQLERSQAEARVLDDDALRKIATLAVATETHNGCPQDIEW MLBr_00955|M.leprae_Br4923 ------------WGPRPLLVSIRSGAVQSMPGMMDTILNLGINDPVEQAL . : Mb2073c|M.bovis_AF2122/97 VGIAERLRPSGVIQREIAMRTVAVFAHRLYGAITSAHFMAATVPFAKPAT Rv2047c|M.tuberculosis_H37Rv VGIAERLRPSGVIQREIAMRTVAVFAHRLYGAITSAHFMAATVPFAKPAT MMAR_3024|M.marinum_M VGIAERLRPGGVIQREIAMRTVAVFAHRLYGAITSAHFMAETVPFAKPAM MUL_2265|M.ulcerans_Agy99 VGIAERLRPGGVIQREIAMRTVAVFAHRLYGAITSAHFMAETVPFAKPAM Mflv_0493|M.gilvum_PYR-GCK MQMVQVAGGVQERYEDRARQVGYFFGHMFLNMTEGTALSSGILGNSLEQF Mvan_1818|M.vanbaalenii_PYR-1 MQMTQVVARAQPRYEKPWLQVGYFYGHMFLNLTEGTALSSGILGNSREQF MAV_5056|M.avium_104 ARYPRTFAGIGRRIARLRSETDAWWRHEIAAVSRLDLRLAQRLAAEARDR TH_4555|M.thermoresistible__bu DRMNARAGFQDLLGQRLYKDKYGTVYWNVDMDEKRLRYVLPRFARPAGAN MSMEG_3934|M.smegmatis_MC2_155 VIADGAVWLVQARPITTLGSAGSTAGDEPSVLIRGLPAAPGVASGRVRVL MLBr_00955|M.leprae_Br4923 AAASPSP-IPQTFARDTRLRFIRTYRRIVDPLNPPPANTYDQLRAAIESI Mb2073c|M.bovis_AF2122/97 IVSNSGFFGPSMASLPIFGAQRPPSESS-RARRWLRTLRNIG--VFGVNL Rv2047c|M.tuberculosis_H37Rv IVSNSGFFGPSMASLPIFGAQRPPSESS-RARRWLRTLRNIG--VFGVNL MMAR_3024|M.marinum_M IVSNSGFFGPSMGSLPIFGEERPPAESS-FVRRQLRTVRNIG--VFGVNL MUL_2265|M.ulcerans_Agy99 IVSNSGFFGPSMGSLPIFGEERPPAESS-FVRRQLCTVRNIG--VFGVNL Mflv_0493|M.gilvum_PYR-GCK SLSVCGRVIDELEPGPPKPFVRKLINTVRLSTFALSSAPAIR--RLPQTI Mvan_1818|M.vanbaalenii_PYR-1 SMSICGRVVDELEAKPPRPFARKLVNTVRLTSHALSAGPAIR--RLADQI MAV_5056|M.avium_104 FFTT-------------------------LAAQAVISATVIQ--PVQEQL TH_4555|M.thermoresistible__bu VVPADMQEQMFAEPLDVVRWLKAMISFSVSPIYSLSRWKKVIREDYLFNE MSMEG_3934|M.smegmatis_MC2_155 LAPDDGDKLTDG-------------EILVAPTTNPDWLPTIR---RAAAL MLBr_00955|M.leprae_Br4923 FSSWN-------------------------SPRAVAYRTHYG-------L . Mb2073c|M.bovis_AF2122/97 VGLSAGSPRDTDAYVADVDRLERLAFDNLATHDDRRLLSLILLARDHVVH Rv2047c|M.tuberculosis_H37Rv VGLSAGSPRDTDAYVADVDRLERLAFDNLATHDDRRLLSLILLARDHVVH MMAR_3024|M.marinum_M VGLSAGSALDTNDFIADVDRLEQLAGGDVTTLDDRRLLSLILLARDHVVH MUL_2265|M.ulcerans_Agy99 VGLSAGSALDTNDFIADVDRLEQLAGGDVTTLDDRRLLSLILLARDHVVH Mflv_0493|M.gilvum_PYR-GCK AAFPPITSRDPAVVLRHLE-------AGVDIYREVTLIHVRSSSRSAVAA Mvan_1818|M.vanbaalenii_PYR-1 AGWPIPSHEDARLVLQQLE-------SGVQLYCDVTLTHVRSSSRAAVAA MAV_5056|M.avium_104 STLCKAAGVDPAVLLRGAS-----------HEENAVLHDLWAASRGALEV TH_4555|M.thermoresistible__bu AAVAKANGLSDAELRALSDDELYRYQRDLQEYAIDFMDPLWFGAYTAMSM MSMEG_3934|M.smegmatis_MC2_155 VTETGGMTCHAAIVARELG-----VPCVVGARSATVALAVGSMVTVDGTR MLBr_00955|M.leprae_Br4923 DDQSGTAVIVQAMVFGNQG----------AYSGAGTLFSRNPITRESKLF Mb2073c|M.bovis_AF2122/97 GWVLASGSFMLCAAFNVLLRGLCGRDTAPAAGPELVSARSVEAVQRLVAA Rv2047c|M.tuberculosis_H37Rv GWVLASGSFMLCAAFNVLLRGLCGRDTAPAAGPELVSARSVEAVQRLVAA MMAR_3024|M.marinum_M GWVLASGSFMLCAAFNVLLRAVSGRDTAPAAGPELVSARSVEAVQRLVAA MUL_2265|M.ulcerans_Agy99 GWVLASGSFMLCAAFNVLLRAVSGRDTAPAAGPELVSARSVEAVQRLVDA Mflv_0493|M.gilvum_PYR-GCK NVLESHLVRRAAKRGASDTAGSAEAIRLMTGAG-VESALMVEELTAVVSM Mvan_1818|M.vanbaalenii_PYR-1 NILESTLVRQAVKNGRSEEEGQAEAARLMAGASDVESAMMLDQLQSVVRA MAV_5056|M.avium_104 DEFVKRHGYHGP------------------GEGELETRVWREDPGAVAGL TH_4555|M.thermoresistible__bu FFSLHAALLAKYYTGTNELLGQDLISGLPTTLQALENRAFFELTSMIRHS MSMEG_3934|M.smegmatis_MC2_155 GEVTTGRLPETVRTTTTPQEPAPHITGEATGTKVYVNLAMPDSAEAVAAQ MLBr_00955|M.leprae_Br4923 GEWLPGGQGDDVVSGLVEVQP-------ITSLRDEQPTVYDELVDTAGRL : Mb2073c|M.bovis_AF2122/97 ARRDPVVIR--LLAEPGERLDKLAVEAPEFHSAVLAELTLIGHRGPAEVE Rv2047c|M.tuberculosis_H37Rv ARRDPVVIR--LLAEPGERLDKLAVEAPEFHSAVLAELTLIGHRGPAEVE MMAR_3024|M.marinum_M ARHDEAVIR--LLSEPGDRLGKLAVAAPHFYDAVRQELSLIGHRGPAEVE MUL_2265|M.ulcerans_Agy99 ARHDEAVIR--LLSEPGDRLGKLAVAAPHFYDAVRQELSLIGHRGPAEVE Mflv_0493|M.gilvum_PYR-GCK LRRDGDAAARFLAAPAGEAVTRLRAAETPSGAALRTFLDRHGHRGYRELC Mvan_1818|M.vanbaalenii_PYR-1 IAADSGVATRFLAAAPDVAVVELQRADNASGEALRQFLLRHGHRGYRELC MAV_5056|M.avium_104 VRR---------------------------------------YSARSDAE TH_4555|M.thermoresistible__bu KVLSDAFEK--HQGAAFFAELENSDEGREFLEKYREFLAEHGHRGHPDRD MSMEG_3934|M.smegmatis_MC2_155 DVDGVGLLR-------------------------AEFMLTEALAGRHPRD MLBr_00955|M.leprae_Br4923 ERLGSDVQE------------------------------IEFTTEDSKLW Mb2073c|M.bovis_AF2122/97 MAATSYADNPELLVRMVAKTLRAVP------------------------- Rv2047c|M.tuberculosis_H37Rv MAATSYADNPELLVRMVAKTLRAVP------------------------- MMAR_3024|M.marinum_M MMSTSYADNPELLVGMVAKTLSTSS------------------------- MUL_2265|M.ulcerans_Agy99 MMSTSYADNPELLVGMVAKTLSTSS------------------------- Mflv_0493|M.gilvum_PYR-GCK MRDPSWADDPDGLGAMMQVMLRGAAPE---------------------NP Mvan_1818|M.vanbaalenii_PYR-1 MRDPSWAQDAGGLGAMMQVMVRAASSD---------------------RQ MAV_5056|M.avium_104 SPDADAAEHHRRRSEAERDLMSSLG------------------------- TH_4555|M.thermoresistible__bu LIFKRRADDPAVDYEAFKVQLQAPEATPPIELEERVRARREAAEAEVIEN MSMEG_3934|M.smegmatis_MC2_155 LITKGEQDTLVDAMAAAVTRIGTAFAP----------------------- MLBr_00955|M.leprae_Br4923 LLQTRVAERSAQVAVRLALQLWQEG------------------------- : : Mb2073c|M.bovis_AF2122/97 -APQPPTPVIPLRAKPVALLAARQLRDREVRRDRMVRAIWVLRALLREYG Rv2047c|M.tuberculosis_H37Rv -APQPPTPVIPLRAKPVALLAARQLRDREVRRDRMVRAIWVLRALLREYG MMAR_3024|M.marinum_M -VPQPPQPSIPLQAKPIAVLAARQLRDREARRDKMVRAIWVLRALLREHG MUL_2265|M.ulcerans_Agy99 -VPQPPQPSIPLQAKPIAVLAARQLRDREARRDKMVRAIWVLRALLREHG Mflv_0493|M.gilvum_PYR-GCK AATAPSDPAQSRTLRVLARLAQAGARGREETKSRMALMAHLLKRGYRHLG Mvan_1818|M.vanbaalenii_PYR-1 PAHSPTEAPTSPAIRFLARLAQGGARGREETKSKMALMAHALKRGYRHLG MAV_5056|M.avium_104 -------PAARVRARLVLRLARNYIPLRGTGKVAYLQSLDVLRAAARRIG TH_4555|M.thermoresistible__bu LGRGFLGPVKQQLFKLLQHQIIDFLVLRDDWRHFIDRITYAKRKAFLEVA MSMEG_3934|M.smegmatis_MC2_155 -RPVIYRAMDFRTNEFRGLAGGEQFEPVEHNPMIGYRGCYRYIKEPDLFA MLBr_00955|M.leprae_Br4923 -------------------LIDDAEALRRVTPVHVETVLLPVLQPENHLS . Mb2073c|M.bovis_AF2122/97 RRLTEAGVFDTPDDVFYLLVDEIDALP-----ADVSGLVARRRA---EQR Rv2047c|M.tuberculosis_H37Rv RRLTEAGVFDTPDDVFYLLVDEIDALP-----ADVSGLVARRRA---EQR MMAR_3024|M.marinum_M RRLAEAGVLHASDDVFYLLVDELDALP-----ADVAELVARRRA---EQR MUL_2265|M.ulcerans_Agy99 RRLAEAGVLHASDDVFYLLVDEVDALP-----ADVAELVARRRA---EQR Mflv_0493|M.gilvum_PYR-GCK EVLHEAGRLPDADLVFFFDRRELPLVVSGDDVTELVHRARQRRE---ALP Mvan_1818|M.vanbaalenii_PYR-1 EVLARSGRLPDADLVFFFDRSELPRVVGDDDISELVQSAVKRRE---ALA MAV_5056|M.avium_104 SLLVEQQRLTDPDDAFYLTIDELTGAPLADAATDLRGTISERRE---IRA TH_4555|M.thermoresistible__bu RRCVERGRLEKEDDAFFLGETELFEVLNGTAKQPLVQAKIAARRPDFELF MSMEG_3934|M.smegmatis_MC2_155 LELSALARAREHTPNIHLMIPFVRTRWELEECLALVDASPLRRHR--NLH MLBr_00955|M.leprae_Br4923 ATLLAKGTPTCPGVISGKAYTEVDEALDAAESAEQVILVRDHTR------ : Mb2073c|M.bovis_AF2122/97 RLAGIVPPTVFSGSWEPSPSSAAALAAGDTLRGVGVCGGRVRGRVRIVR- Rv2047c|M.tuberculosis_H37Rv RLAGIVPPTVFSGSWEPSPSSAAALAAGDTLRGVGVCGGRVRGRVRIVR- MMAR_3024|M.marinum_M RLTAVVPPTVFSGKWEPSTASAAALTAGGTLRGVGVCGGRVRGRVRIVR- MUL_2265|M.ulcerans_Agy99 RLTAVVPPTVFSGKWEPSTASAAALTAEGTLRGVGVCGGRVRGRVRIVR- Mflv_0493|M.gilvum_PYR-GCK FQAALEFGDVSVGRPTPIVR--AAVSGDGVVAGRPAGHGSVEGVVRVARS Mvan_1818|M.vanbaalenii_PYR-1 YQDSLEFEDVSVGRPRPVVAPPVITSTADQVVGRPASRGTVEGTVRVAKT MAV_5056|M.avium_104 HYQSLTLPSAWTGQPEPLAPSASAETSVRSLRGIGACAGVAEGRAVVVT- TH_4555|M.thermoresistible__bu ESRTFTPPMFMRGETPVDEAAPAAVAGSGAINGVGTSAGQVEGRARVLAS MSMEG_3934|M.smegmatis_MC2_155 RWVMAEVPSVVHWLP-----EYVGMGIDGVSIGSNDLTQLMLGVDRDSET MLBr_00955|M.leprae_Br4923 -PDDVLGMLASQGVVTEVGGAASHAAVVSRELSRVAVVGCGQGTAVSLAG . * Mb2073c|M.bovis_AF2122/97 PETIDDLQPGEILVAEVTDVGYTAAFCYAAAVVTELGGPMSHAAVVAREF Rv2047c|M.tuberculosis_H37Rv PETIDDLQPGEILVAEVTDVGYTAAFCYAAAVVTELGGPMSHAAVVAREF MMAR_3024|M.marinum_M PETIDELEPGEILVAEVTDVGYTAAFCYAAAVVTELGGPMSHAAVVAREF MUL_2265|M.ulcerans_Agy99 PETIDELEPGEILVAEVTDVGYTAAFCYAAAVVTELGGPMSHAAVVAREF Mflv_0493|M.gilvum_PYR-GCK VVEARDLQPGEILVAPVTDVGWTPYFAVIAALVTDIGSSVSHGAVVAREY Mvan_1818|M.vanbaalenii_PYR-1 IQDARDVQRGEILVAPVTDVGWTPYFTVIAALITDIGSSVSHGAVVAREY MAV_5056|M.avium_104 DPTETEIADGDILIAQTTDPSWVSLMFLSAALVVDIGGLMSHAAVMAREL TH_4555|M.thermoresistible__bu MTEIGTLEQGDVLVCNATDPGWSPVFGVISGLIIETGGMLAHGACLSREH MSMEG_3934|M.smegmatis_MC2_155 CAELFDESDAAVLDAISRIISTANRLGITSSLCGQAPSTRPEFAEHLVRM MLBr_00955|M.leprae_Br4923 KQITVDGDKGEVRQGNLTLSAWSENETPELRELADIARRISPLRVHMTED . : . : . . Mb2073c|M.bovis_AF2122/97 GFPCVVDAQGATRFLPPGALVEVDGATGEIHVVELASEDGPALPGSDLSR Rv2047c|M.tuberculosis_H37Rv GFPCVVDAQGATRFLPPGALVEVDGATGEIHVVELASEDGPALPGSDLSR MMAR_3024|M.marinum_M GFPCVVDAQGATRFLPPGALIEVDGTTGEIQVLELAAEGDSSVTQSDPAD MUL_2265|M.ulcerans_Agy99 GFPCVVDAQGATRFLPPGALIEVDGTTGEIQVLELAAEGDSSVTQSDPAD Mflv_0493|M.gilvum_PYR-GCK GLPCVVNTLVGTQVLRTGDRVRVDGDRGLVTVLDSP-------------- Mvan_1818|M.vanbaalenii_PYR-1 GLPCVVNTLVGTQVLRTGDRVRVDGDRGVVTRLG---------------- MAV_5056|M.avium_104 GIPCVMNTGTGTTALRTGDTIRVDGAAGTVEILSRNIQQSSIPERTH--- TH_4555|M.thermoresistible__bu GIPAVQIVG-ATQIIPDGAYVRINGTTGLVEVLEPAPAGAA--------- MSMEG_3934|M.smegmatis_MC2_155 GITSVSVNPDAAGAARR--AVAAAERRLLLDSVRHPRHAPTASPRNPL-- MLBr_00955|M.leprae_Br4923 HTRLDDSSDTAVRLAINTGHADVVSATPLIVMMTTLRLQDSKDSSAKS-- .. : : Mb2073c|M.bovis_AF2122/97 -- Rv2047c|M.tuberculosis_H37Rv -- MMAR_3024|M.marinum_M LA MUL_2265|M.ulcerans_Agy99 LA Mflv_0493|M.gilvum_PYR-GCK -- Mvan_1818|M.vanbaalenii_PYR-1 -- MAV_5056|M.avium_104 -- TH_4555|M.thermoresistible__bu -- MSMEG_3934|M.smegmatis_MC2_155 -- MLBr_00955|M.leprae_Br4923 --