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VFDASSRIVDLADVLDDSFGGKALGLAELTRLGLPVPPGFVIADASGTSLGDAVTERFSRMRAAGQTPVA VRSSAAGEDGAEHSFAGQYDTVLGVGSVDELTAAVEKCVRSAGSERAAAYQDGGAAARMHLVVQQMVDAR AAGVVFTADPTSGRRDLLVIDAVRGLGESLVDGSTASDHFVLTHAGDTVTTEASSQPALADDEIDRIRTG ALLAAAHWGRPLDLEWAIDRDGLLWWLQARPITTLPGDPNEMDTPVTGPTHVYTRCNIGEMMPGAFCPLT ASVSGHAIDYAMQMVQVAGGVQERYEDRARQVGYFFGHMFLNMTEGTALSSGILGNSLEQFSLSVCGRVI DELEPGPPKPFVRKLINTVRLSTFALSSAPAIRRLPQTIAAFPPITSRDPAVVLRHLEAGVDIYREVTLI HVRSSSRSAVAANVLESHLVRRAAKRGASDTAGSAEAIRLMTGAGVESALMVEELTAVVSMLRRDGDAAA RFLAAPAGEAVTRLRAAETPSGAALRTFLDRHGHRGYRELCMRDPSWADDPDGLGAMMQVMLRGAAPENP AATAPSDPAQSRTLRVLARLAQAGARGREETKSRMALMAHLLKRGYRHLGEVLHEAGRLPDADLVFFFDR RELPLVVSGDDVTELVHRARQRREALPFQAALEFGDVSVGRPTPIVRAAVSGDGVVAGRPAGHGSVEGVV RVARSVVEARDLQPGEILVAPVTDVGWTPYFAVIAALVTDIGSSVSHGAVVAREYGLPCVVNTLVGTQVL RTGDRVRVDGDRGLVTVLDSP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0493 | - | - | 100% (791) | pyruvate, water dikinase |
| M. gilvum PYR-GCK | Mflv_4990 | - | 2e-29 | 33.11% (299) | phosphoenolpyruvate synthase |
| M. gilvum PYR-GCK | Mflv_0749 | - | 4e-08 | 42.03% (69) | phosphoenolpyruvate-protein phosphotransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2073c | - | 6e-39 | 31.24% (573) | hypothetical protein Mb2073c |
| M. tuberculosis H37Rv | Rv2047c | - | 6e-39 | 31.24% (573) | hypothetical protein Rv2047c |
| M. leprae Br4923 | MLBr_00955 | ppdK | 2e-05 | 44.90% (49) | pyruvate phosphate dikinase |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_3024 | - | 3e-40 | 30.98% (581) | hypothetical protein MMAR_3024 |
| M. avium 104 | MAV_2451 | - | 2e-37 | 30.77% (572) | hypothetical protein MAV_2451 |
| M. smegmatis MC2 155 | MSMEG_3934 | - | 1e-28 | 33.12% (317) | phosphoenolpyruvate synthase |
| M. thermoresistible (build 8) | TH_3290 | - | 3e-50 | 26.47% (899) | PUTATIVE putative phosphoenolpyruvate synthase |
| M. ulcerans Agy99 | MUL_2265 | - | 5e-40 | 30.81% (581) | hypothetical protein MUL_2265 |
| M. vanbaalenii PYR-1 | Mvan_1818 | - | 0.0 | 68.33% (783) | pyruvate, water dikinase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0493|M.gilvum_PYR-GCK -------------------MFDASSRIVDLADVLDDSFGGKALGLAELTR
Mvan_1818|M.vanbaalenii_PYR-1 ----------------------MAPATIEFDDVTDDRFGGKAAGLAELRR
Mb2073c|M.bovis_AF2122/97 MRIAVTGASGVLGRGLTARLLSQGHEVVGIARHRPDSWPSSADFIAADIR
Rv2047c|M.tuberculosis_H37Rv MRIAVTGASGVLGRGLTARLLSQGHEVVGIARHRPDSWPSSADFIAADIR
MMAR_3024|M.marinum_M MRVAVTGAGGVLGRGLASRLLSQGHEVVGMSRRRPDSWPSQADFVAGDIR
MUL_2265|M.ulcerans_Agy99 MRVAVTGAGGVLGRGLASRLLSQGHEVVGMSRRRPDSWPSQADFVAGDIR
MAV_2451|M.avium_104 MRIAVTGASGVLGRGLAARLLSKGHDVVGIARHRPDSWSSAADFIEADIR
TH_3290|M.thermoresistible__bu ------------MPNIVQINSAATDSAASAQLTERALVGGKGRHLMLCSA
MSMEG_3934|M.smegmatis_MC2_155 ---------------MDIMSDRYVRTLDILTIADAEEAGGKGANLGELVA
MLBr_00955|M.leprae_Br4923 ------------------MPGQSHKEPHRRATSTPRSLKQATSELRWALS
:
Mflv_0493|M.gilvum_PYR-GCK LGLPVPPGFVIADASGTS----------------LGDAVTERFSRMRAAG
Mvan_1818|M.vanbaalenii_PYR-1 IGLSVPVGFVIADASAHG----------------ALDAAVDRFCQMAAEG
Mb2073c|M.bovis_AF2122/97 DATAVESAMTGADVVAHCAWVRGR------NDHINIDGTANVLKAMAETG
Rv2047c|M.tuberculosis_H37Rv DATAVESAMTGADVVAHCAWVRGR------NDHINIDGTANVLKAMAETG
MMAR_3024|M.marinum_M DAAAVRRAITGADVVAHCAWARNPGPDGRISQQINIDGTRNVLDAMAACG
MUL_2265|M.ulcerans_Agy99 DAAAVRRAITGADVVAHCAWARNPGPDGRISQQINIDGTRNVLDAMAACG
MAV_2451|M.avium_104 DAAAVNRAVTSADVVAHFAWTHDT--QERTGSQVNIAGTANVLAAMAETS
TH_3290|M.thermoresistible__bu AGFPVPPGFTITTDAYDAFLAHNK-----LTDTVAKSAAAFVYHDVDTLE
MSMEG_3934|M.smegmatis_MC2_155 ADLPVPHGFVVMRSAYLDSVRMGG---VEAELAALHTEALTHAADTARLS
MLBr_00955|M.leprae_Br4923 LAAPESPAFMRHLLGNAH----------------DKVDITTSSEHVAAFT
. ..
Mflv_0493|M.gilvum_PYR-GCK QTPVAVRSS--------------------------------AAGEDGAEH
Mvan_1818|M.vanbaalenii_PYR-1 VTPVAVRSS--------------------------------AVGEDGEDQ
Mb2073c|M.bovis_AF2122/97 TGRIVFTSS-------------------------GHQPRVEQMLADCGLE
Rv2047c|M.tuberculosis_H37Rv TGRIVFTSS-------------------------GHQPRVEQMLADCGLE
MMAR_3024|M.marinum_M TGRIVFPSSPHVYRPGVPMPATEHGAVAPASAEGRHKAGVEQMLQESGAQ
MUL_2265|M.ulcerans_Agy99 TGRIVFPSSPHVYRPGLPMPATEHGAVAPASAEGRHKAGVEQMLQESGAQ
MAV_2451|M.avium_104 ARRIVFPSSPHVYGGG-DTPRSEAEAPAPSAADAVQQARVEEMLVASGLE
TH_3290|M.thermoresistible__bu QQATAIQEVILN--GQIPPALAEEVAARYSELGGYVAVRSSGTAEDMADA
MSMEG_3934|M.smegmatis_MC2_155 ELCRRMQSLVNKAGLSPSVRDATLAAYRALGTDVVVAVRSSATGEDGRDA
MLBr_00955|M.leprae_Br4923 EHAIVLLNG-----------------------------------NAHQTR
. .
Mflv_0493|M.gilvum_PYR-GCK SFAGQYDTVLG---VGSVDELTAAVEKCVRSAGSERAAAYQDGGAAAR--
Mvan_1818|M.vanbaalenii_PYR-1 SFAGQYDTVLG---VASVDDFTAAVRRCAGSVASQRASSYS-GHSPAT--
Mb2073c|M.bovis_AF2122/97 WVAVRCALIFGRNVDNWVQRLFALPVLPAGYADRVVQVVHSDDAQRLL--
Rv2047c|M.tuberculosis_H37Rv WVAVRCALIFGRNVDNWVQRLFALPVLPAGYADRVVQVVHSDDAQRLL--
MMAR_3024|M.marinum_M WVAVRSALIVGRNIDNWVRRLFALPAFPDGSADDVLQVVHLDDVLRLL--
MUL_2265|M.ulcerans_Agy99 WVAVRSALIVGRNIDNWVRRLFALPAFPDGSADDVLQVVHLDDVLRLL--
MAV_2451|M.avium_104 SVTIRCALVVGRNVDNWVRRVLALPAFPGGTVDRPIQLVHLDDALRLL--
TH_3290|M.thermoresistible__bu SFAGLHDTFLD---ITGEDALLEAVKKCWASLWTSRAIAYRGEQGHAPGA
MSMEG_3934|M.smegmatis_MC2_155 SFAGMNRTITN---VMGEVALLDAVTQCWMSLFSPRVITYRASRGFTAAP
MLBr_00955|M.leprae_Br4923 ELLGGKGYNIN---AMRRHQLAVPPAFCITTEVGVRYLAAPTPTMEAIWN
. . .
Mflv_0493|M.gilvum_PYR-GCK ---MHLVVQQMVDARAAGVVFTADPTSGRRDLLVIDAVRGLGESLVDGST
Mvan_1818|M.vanbaalenii_PYR-1 ---MHVVVQQMVDARAAGVVFTADPATGRRDLMVIDAIAGLGEALVDGSA
Mb2073c|M.bovis_AF2122/97 ---VRALLDTVIDSGPVNLAAPGELTFRRIAAALGRPMVPIGSPVLRRVT
Rv2047c|M.tuberculosis_H37Rv ---VRALLDTVIDSGPVNLAAPGELTFRRIAAALGRPMVPIGSPVLRRVT
MMAR_3024|M.marinum_M ---TRAVSDVGAGTGPVNLAAPGLPTLREIAMALRRPILPVG-AVLRRIG
MUL_2265|M.ulcerans_Agy99 ---TRAVSDVGAGTGPVNLAAPGLPTLREIATALRRPILPVG-AALRRIG
MAV_2451|M.avium_104 ---ESAVLSHEIPSGTVNLAAPGTTTFRRIAATLRRPVLRLG------RP
TH_3290|M.thermoresistible__bu LPKLAVVVQQMVEADAAGVMFTANPLTSNTDEIVVNSCWGLGEGLVSGIV
MSMEG_3934|M.smegmatis_MC2_155 --AMAVVVQQMLSADRAGVAFTSDPSTGDADHIVIEAAFGQGEVVVSGKV
MLBr_00955|M.leprae_Br4923 --DVLDQMRWLEAETSRTFGWGPRPLLVSIRSGAVQSMPGMMDTILNLGI
. .
Mflv_0493|M.gilvum_PYR-GCK ASDHFVLTHAG-----DTVTTEASSQP----------------------A
Mvan_1818|M.vanbaalenii_PYR-1 SPDHVVLNADG-----STAVREVGTAP----------------------V
Mb2073c|M.bovis_AF2122/97 SFAELELLHSAPLMDVTLLRDRWGFQP----------------------A
Rv2047c|M.tuberculosis_H37Rv SFAELELLHSAPLMDVTLLRDRWGFQP----------------------A
MMAR_3024|M.marinum_M SVAEFQLVQGVPVMDTARLHDEWKFQP----------------------A
MUL_2265|M.ulcerans_Agy99 SVAEFQLVQGVPVMDTARLHDEWKFQP----------------------A
MAV_2451|M.avium_104 APAELEPVLSAPLMDTALLHERWGFRP----------------------A
TH_3290|M.thermoresistible__bu NPDQFVLGKDRLAIKERMLGDKAVTVKRNPDGPDSTVSVPTPEPKREAWS
MSMEG_3934|M.smegmatis_MC2_155 EPDTYVIDKRTLEVRDVRIGFKAIKIVR----------------------
MLBr_00955|M.leprae_Br4923 NDP-----------------------------------------------
Mflv_0493|M.gilvum_PYR-GCK LADDEIDRIRTGALLAAAHWG-RPLDLEWAIDRDGLLWWLQARPITTLP-
Mvan_1818|M.vanbaalenii_PYR-1 LSSDDVAEIRSGALRAARHWG-RPLDLEWAIDGTGKLWWLQARPITTLP-
Mb2073c|M.bovis_AF2122/97 WNAEECLEDFTLAVRGRIGLGKRTFSLPWRLANIQDLPAVDSPADDGVAP
Rv2047c|M.tuberculosis_H37Rv WNAEECLEDFTLAVRGRIGLGKRTFSLPWRLANIQDLPAVDSPADDGVAP
MMAR_3024|M.marinum_M FTAEESVEDFALAVRGRVSLGRRVVSLPWRLANIQDLPAVDAPAQDGVVP
MUL_2265|M.ulcerans_Agy99 FTAEESVEDFALAVRGRVSLGRRVVSLPWRLANIQDLPAIDASAQDGVVP
MAV_2451|M.avium_104 WQCGECVEDMALAVRGRVTVGRRVVSLPWRLANVADLPAVDAPAQDGVVP
TH_3290|M.thermoresistible__bu IADDTVVRLGELARRIERYFDGLPQDIEWAVKD-NEIFVLQSRAITGVDF
MSMEG_3934|M.smegmatis_MC2_155 --GDDGADSMVQLERSQAEARVLDDDALRKIATLAVATETHNGCP-----
MLBr_00955|M.leprae_Br4923 ------------VEQALAAASPSPIPQTFARDTRLRFIRTYRRIVDPLN-
Mflv_0493|M.gilvum_PYR-GCK ------GDPNEMDTPVTGPTHVYTRCNIGEMMPGAFCPLTASVSGHAIDY
Mvan_1818|M.vanbaalenii_PYR-1 ------GDLNEMDSPVAGSDHVYTRCNIGEMMPGAFCPLTASVSGYAIDY
Mb2073c|M.bovis_AF2122/97 RLAGPEGANGEFDTPIDPRFPTYLATNLSEALPGPFSPSSASVTVRGLRA
Rv2047c|M.tuberculosis_H37Rv RLAGPEGANGEFDTPIDPRFPTYLATNLSEALPGPFSPSSASVTVRGLRA
MMAR_3024|M.marinum_M RLAGPEGVNGEFDTPIDPRFPTFLATNLSEALPGPFSPSSASVTVRGLRA
MUL_2265|M.ulcerans_Agy99 RLAGPEGVNGEFDTPIDPRFPTFLATNLSEALPGPFSPSSASVTVRGLRA
MAV_2451|M.avium_104 VPAGPEGVNGEFDTPIDPRFPTFLATNLSEALPGPFSPSSASATVRGVRA
TH_3290|M.thermoresistible__bu T---WDSDVDAWQEAEDEPEAIWTRKFADEFWTGPITPLFYSVRARGFTN
MSMEG_3934|M.smegmatis_MC2_155 -------QDIEWVIADGAVWLVQARPITTLGSAGSTAGDEPSVLIRGLPA
MLBr_00955|M.leprae_Br4923 --------------PPPANTYDQLRAAIESIFSSWNSPRAVAYRTHYGLD
. .. :
Mflv_0493|M.gilvum_PYR-GCK -AMQMVQVAGGVQERYEDRARQVGYFFGHMFLNMTEGTALSSGILGNSLE
Mvan_1818|M.vanbaalenii_PYR-1 -AMQMTQVVARAQPRYEKPWLQVGYFYGHMFLNLTEGTALSSGILGNSRE
Mb2073c|M.bovis_AF2122/97 GGVGIAERLRPSGVIQREIAMRTVAVFAHRLYGAITSAHFMAATVPFAKP
Rv2047c|M.tuberculosis_H37Rv GGVGIAERLRPSGVIQREIAMRTVAVFAHRLYGAITSAHFMAATVPFAKP
MMAR_3024|M.marinum_M GGVGIAERLRPGGVIQREIAMRTVAVFAHRLYGAITSAHFMAETVPFAKP
MUL_2265|M.ulcerans_Agy99 GGVGIAERLRPGGVIQREIAMRTVAVFAHRLYGAITSAHFMAETVPFAKP
MAV_2451|M.avium_104 GGVTIAERLRPGGLVQREIALRTVGVFAHRLYGAITSAHFMAETVPFAKP
TH_3290|M.thermoresistible__bu AGVRSALDWG---FADVAAKRRHKYFKAEVYTNSEYQKALVSHAIPKSMR
MSMEG_3934|M.smegmatis_MC2_155 APGVASGRVRVLLAPDDGDKLTDGEILVAPTTNPDWLPTIRRAAALVTET
MLBr_00955|M.leprae_Br4923 DQSGTAVIVQAMVFGNQGAYSGAGTLFSR--NPITRESKLFGEWLPGGQG
. :
Mflv_0493|M.gilvum_PYR-GCK QFSLSVCGRVIDELEPGPPKPFVRKLINTVRLSTFALSSAPAIRRLPQT-
Mvan_1818|M.vanbaalenii_PYR-1 QFSMSICGRVVDELEAKPPRPFARKLVNTVRLTSHALSAGPAIRRLADQ-
Mb2073c|M.bovis_AF2122/97 ATIVSNSGFFGPSMASLPIFGAQRPPSESSRAR-RWLRTLRNIGVFGVN-
Rv2047c|M.tuberculosis_H37Rv ATIVSNSGFFGPSMASLPIFGAQRPPSESSRAR-RWLRTLRNIGVFGVN-
MMAR_3024|M.marinum_M AMIVSNSGFFGPSMGSLPIFGEERPPAESSFVR-RQLRTVRNIGVFGVN-
MUL_2265|M.ulcerans_Agy99 AMIVSNSGFFGPSMGSLPIFGEERPPAESSFVR-RQLCTVRNIGVFGVN-
MAV_2451|M.avium_104 SMIVSNSGFFGPSMASLPVFGEQRP-AETGWAR-RLLRNTRNIGVFGVN-
TH_3290|M.thermoresistible__bu EGSVAWLNSADRKAAASWPFSWREYVRMLARIQFMTQNGLYEWFKEADNY
MSMEG_3934|M.smegmatis_MC2_155 GGMTCHAAIVARELGVPCVVGARSATVALAVGSMVTVDGTRGEVTTGRLP
MLBr_00955|M.leprae_Br4923 DDVVSGLVEVQPITSLRDEQPTVYDELVDTAGRLERLGSDVQEIEFTTE-
.
Mflv_0493|M.gilvum_PYR-GCK -IAAFPPITSRDPAVVLRHLE-------AGVDIYREVTLIHVRSSSRSAV
Mvan_1818|M.vanbaalenii_PYR-1 -IAGWPIPSHEDARLVLQQLE-------SGVQLYCDVTLTHVRSSSRAAV
Mb2073c|M.bovis_AF2122/97 -LVGLSAGSPRDTDAYVADVDRLERLAFDNLATHDDRRLLSLILLARDHV
Rv2047c|M.tuberculosis_H37Rv -LVGLSAGSPRDTDAYVADVDRLERLAFDNLATHDDRRLLSLILLARDHV
MMAR_3024|M.marinum_M -LVGLSAGSALDTNDFIADVDRLEQLAGGDVTTLDDRRLLSLILLARDHV
MUL_2265|M.ulcerans_Agy99 -LVGLSAGSALDTNDFIADVDRLEQLAGGDVTTLDDRRLLSLILLARDHV
MAV_2451|M.avium_104 -LVGLSSGAARDTDDFIADVDRLERLAG-DAAELDERRLLSLIALARDQV
TH_3290|M.thermoresistible__bu DLEKVPERGRLDPEALKLWSDEALR---RLIKQYTDYAENKHYSQWTGWF
MSMEG_3934|M.smegmatis_MC2_155 ETVRTTTTPQEPAPHITGEATG------------TKVYVNLAMPDSAEAV
MLBr_00955|M.leprae_Br4923 ---------------------------------DSKLWLLQTRVAERSAQ
.
Mflv_0493|M.gilvum_PYR-GCK AANVLESHLVRRAAKRGASDTAGSAEAIRLMTGAG-VESALMVEELTAVV
Mvan_1818|M.vanbaalenii_PYR-1 AANILESTLVRQAVKNGRSEEEGQAEAARLMAGASDVESAMMLDQLQSVV
Mb2073c|M.bovis_AF2122/97 VHGWVLASGSFMLCAAFNVLLRGLCGRDTAPAAGPELVSARSVEAVQRLV
Rv2047c|M.tuberculosis_H37Rv VHGWVLASGSFMLCAAFNVLLRGLCGRDTAPAAGPELVSARSVEAVQRLV
MMAR_3024|M.marinum_M VHGWVLASGSFMLCAAFNVLLRAVSGRDTAPAAGPELVSARSVEAVQRLV
MUL_2265|M.ulcerans_Agy99 VHGWVLASGSFMLCAAFNVLLRAVSGRDTAPAAGPELVSARSVEAVQRLV
MAV_2451|M.avium_104 VHGWVLASASFMLCAAFNVLLRAVCGRDTSAPAGPELVSARSVEAMQRLV
TH_3290|M.thermoresistible__bu IHAANAMTILGKMLASWYDGTNANIFTDLITGLPERTRTMQENIDLWQLA
MSMEG_3934|M.smegmatis_MC2_155 AAQDVDGVGLLRAEFMLTEALAGRHPRDLITKGEQDTLVDAMAAAVTRIG
MLBr_00955|M.leprae_Br4923 VAVRLALQLWQEGLIDDAEALRRVTPVHVETVLLPVLQPENHLSATLLAK
Mflv_0493|M.gilvum_PYR-GCK SMLRRDGDAAARFLAAPAGEAVTRLRAAET--PSGAALRTFLDRHGHRGY
Mvan_1818|M.vanbaalenii_PYR-1 RAIAADSGVATRFLAAAPDVAVVELQRADN--ASGEALRQFLLRHGHRGY
Mb2073c|M.bovis_AF2122/97 AAARRDPVVIR--LLAEPGERLDKLAVEAP--EFHSAVLAELTLIGHRGP
Rv2047c|M.tuberculosis_H37Rv AAARRDPVVIR--LLAEPGERLDKLAVEAP--EFHSAVLAELTLIGHRGP
MMAR_3024|M.marinum_M AAARHDEAVIR--LLSEPGDRLGKLAVAAP--HFYDAVRQELSLIGHRGP
MUL_2265|M.ulcerans_Agy99 DAARHDEAVIR--LLSEPGDRLGKLAVAAP--HFYDAVRQELSLIGHRGP
MAV_2451|M.avium_104 VAAQRDPNVAR--VLTEPGERLDKLAVDAP--EFHAAVLAELALIGHRGP
TH_3290|M.thermoresistible__bu SAIRSNAAVRELFEKSSETEFFDRLADLPEGASVYAQYREFLDLHGHRGH
MSMEG_3934|M.smegmatis_MC2_155 TAFAPRPVIYR--AMDFRTNEFRGLAGGEQ-----FEPVEHNPMIGYRG-
MLBr_00955|M.leprae_Br4923 GTPTCPGVISG----KAYTEVDEALDAAES--------------------
*
Mflv_0493|M.gilvum_PYR-GCK RELCMRDPSWADDPDGLGAMMQVMLRGAAPEN------------------
Mvan_1818|M.vanbaalenii_PYR-1 RELCMRDPSWAQDAGGLGAMMQVMVRAASSDR------------------
Mb2073c|M.bovis_AF2122/97 AEVEMAATSYADNPELLVRMVAKTLRAVP---------------------
Rv2047c|M.tuberculosis_H37Rv AEVEMAATSYADNPELLVRMVAKTLRAVP---------------------
MMAR_3024|M.marinum_M AEVEMMSTSYADNPELLVGMVAKTLSTSS---------------------
MUL_2265|M.ulcerans_Agy99 AEVEMMSTSYADNPELLVGMVAKTLSTSS---------------------
MAV_2451|M.avium_104 AELEMLSTSYADDPELLVRMVAKAMAATA---------------------
TH_3290|M.thermoresistible__bu ADRDFYFPRRLDDPAIDYRLLKALLSGDGSFDPVAAEKELQRRREAAVAD
MSMEG_3934|M.smegmatis_MC2_155 ------CYRYIKEPD-----------------------------------
MLBr_00955|M.leprae_Br4923 --------------------------------------------------
Mflv_0493|M.gilvum_PYR-GCK ---PAATAPSDPAQSRTLRVLARLAQAGARGREETKSRMALMAHLLKRGY
Mvan_1818|M.vanbaalenii_PYR-1 ---QPAHSPTEAPTSPAIRFLARLAQGGARGREETKSKMALMAHALKRGY
Mb2073c|M.bovis_AF2122/97 -----APQPPTPVIPLRAKPVALLAARQLRDREVRRDRMVRAIWVLRALL
Rv2047c|M.tuberculosis_H37Rv -----APQPPTPVIPLRAKPVALLAARQLRDREVRRDRMVRAIWVLRALL
MMAR_3024|M.marinum_M -----VPQPPQPSIPLQAKPIAVLAARQLRDREARRDKMVRAIWVLRALL
MUL_2265|M.ulcerans_Agy99 -----VPQPPQPSIPLQAKPIAVLAARQLRDREARRDKMVRAIWVLRALL
MAV_2451|M.avium_104 -----APPPQHPRIPLQAKLIAALTARQLRDREARRDKVVRANWVLRALL
TH_3290|M.thermoresistible__bu VLDRLRNQPMGALRVAAFNTVYKYVVRFMLHRDNQRHHLDRVTYAKKLAF
MSMEG_3934|M.smegmatis_MC2_155 -------------------LFALELSALARAREHTPNIHLMIPFVRTRWE
MLBr_00955|M.leprae_Br4923 ------------------------AEQVILVRDHTRPDDVLGMLASQGVV
*:
Mflv_0493|M.gilvum_PYR-GCK RHLGEVLHEAGRLPDADLVFFFDRRELPLVVSGDDVTELVHRARQ-RREA
Mvan_1818|M.vanbaalenii_PYR-1 RHLGEVLARSGRLPDADLVFFFDRSELPRVVGDDDISELVQSAVK-RREA
Mb2073c|M.bovis_AF2122/97 REYGRRLTEAGVFDTPDDVFYLLVDEIDALP-----ADVSGLVAR-RRAE
Rv2047c|M.tuberculosis_H37Rv REYGRRLTEAGVFDTPDDVFYLLVDEIDALP-----ADVSGLVAR-RRAE
MMAR_3024|M.marinum_M REHGRRLAEAGVLHASDDVFYLLVDELDALP-----ADVAELVAR-RRAE
MUL_2265|M.ulcerans_Agy99 REHGRRLAEAGVLHASDDVFYLLVDEVDALP-----ADVAELVAR-RRAE
MAV_2451|M.avium_104 REYGRRLTHAGVFGSADDVFYLLVDELDALP-----ADVAAVVAR-RRAE
TH_3290|M.thermoresistible__bu TEVGRRVHERGLLPREDDFYFLTEDELFGLLHGTGNARLCQAKVIGRRNA
MSMEG_3934|M.smegmatis_MC2_155 LEECLALVDASPLRRHRNLHRWVMAEVPSVV-----------------HW
MLBr_00955|M.leprae_Br4923 TEVGGAASHAAVVSR----------ELSRVA-------------------
. . . *: :
Mflv_0493|M.gilvum_PYR-GCK LPFQAA---LEFGDVSVGR--PTPIVR--AAVSGDGVVAGRPAGHGSVEG
Mvan_1818|M.vanbaalenii_PYR-1 LAYQDS---LEFEDVSVGR--PRPVVAPPVITSTADQVVGRPASRGTVEG
Mb2073c|M.bovis_AF2122/97 QRRLAG---IVPPTVFSGS--WEPSPSSAAALAAGDTLRGVGVCGGRVRG
Rv2047c|M.tuberculosis_H37Rv QRRLAG---IVPPTVFSGS--WEPSPSSAAALAAGDTLRGVGVCGGRVRG
MMAR_3024|M.marinum_M QRRLTA---VVPPTVFSGK--WEPSTASAAALTAGGTLRGVGVCGGRVRG
MUL_2265|M.ulcerans_Agy99 QRRLTA---VVPPTVFSGK--WEPSTASAAALTAEGTLRGVGVCGGRVRG
MAV_2451|M.avium_104 HRRLAG---IAPPTVFSGS--WQPTATSVPALAGGGTLRGVGVCGGRVRG
TH_3290|M.thermoresistible__bu FEQYASGKFVPPEFMQNGREWVDPEAQQLQVADDGSGIQGFGTSPGTYTG
MSMEG_3934|M.smegmatis_MC2_155 LPEYVG---MGIDGVSIGS---NDLTQLMLGVDRDSETCAELFDESDAAV
MLBr_00955|M.leprae_Br4923 -------------VVGCGQG---------TAVSLAGKQITVDGDKGEVRQ
: * . .
Mflv_0493|M.gilvum_PYR-GCK VVRVARSVVEARDLQPGEILVAPVTDVGWTPYFAVIAALVTDIGSSVSHG
Mvan_1818|M.vanbaalenii_PYR-1 TVRVAKTIQDARDVQRGEILVAPVTDVGWTPYFTVIAALITDIGSSVSHG
Mb2073c|M.bovis_AF2122/97 RVRIVR-PETIDDLQPGEILVAEVTDVGYTAAFCYAAAVVTELGGPMSHA
Rv2047c|M.tuberculosis_H37Rv RVRIVR-PETIDDLQPGEILVAEVTDVGYTAAFCYAAAVVTELGGPMSHA
MMAR_3024|M.marinum_M RVRIVR-PETIDELEPGEILVAEVTDVGYTAAFCYAAAVVTELGGPMSHA
MUL_2265|M.ulcerans_Agy99 RVRIVR-PETIDELEPGEILVAEVTDVGYTAAFCYAAAVVTELGGPMSHA
MAV_2451|M.avium_104 RVRIVR-PETIDDLQPGEILVAEATDVGYTAAFCYAAAVVTELGGPMSHA
TH_3290|M.thermoresistible__bu RARVITSLDDIGRVEQGDVLITNSTDPAWTPVFLVIGGLVLETGGLLAHG
MSMEG_3934|M.smegmatis_MC2_155 LDAISRIISTANRLGITSSLCGQAPSTRPEFAEHLVRMGITSVSVNPDAA
MLBr_00955|M.leprae_Br4923 GNLTLSAWSENETPELRELADIARRISPLRVHMTEDHTRLDDSSDTAVRL
. : . .
Mflv_0493|M.gilvum_PYR-GCK AVVAREYGLPCVVNTLVGTQVLRTGDRVRVDGDRGLVTVLDSP-------
Mvan_1818|M.vanbaalenii_PYR-1 AVVAREYGLPCVVNTLVGTQVLRTGDRVRVDGDRGVVTRLG---------
Mb2073c|M.bovis_AF2122/97 AVVAREFGFPCVVDAQGATRFLPPGALVEVDGATGEIHVVELASEDGPAL
Rv2047c|M.tuberculosis_H37Rv AVVAREFGFPCVVDAQGATRFLPPGALVEVDGATGEIHVVELASEDGPAL
MMAR_3024|M.marinum_M AVVAREFGFPCVVDAQGATRFLPPGALIEVDGTTGEIQVLELAAEGDSSV
MUL_2265|M.ulcerans_Agy99 AVVAREFGFPCVVDAQGATRFLPPGALIEVDGTTGEIQVLELAAEGDSSV
MAV_2451|M.avium_104 AVVAREFGFPCVVDVQGATKSLPPGALVEVDGATGEIRVLELASEPATGG
TH_3290|M.thermoresistible__bu ACLSREYNLPAVT-APAATTRIPDGATITVDGVAGTVIVHQEATVQ----
MSMEG_3934|M.smegmatis_MC2_155 GAARRAVAAAERRLLLDSVRHPRHAPTASPRNPL----------------
MLBr_00955|M.leprae_Br4923 AINTGHADVVSATPLIVMMTTLRLQDSKDSSAKS----------------
.
Mflv_0493|M.gilvum_PYR-GCK ---------
Mvan_1818|M.vanbaalenii_PYR-1 ---------
Mb2073c|M.bovis_AF2122/97 PGSDLSR--
Rv2047c|M.tuberculosis_H37Rv PGSDLSR--
MMAR_3024|M.marinum_M TQSDPADLA
MUL_2265|M.ulcerans_Agy99 TQSDPADLA
MAV_2451|M.avium_104 G--------
TH_3290|M.thermoresistible__bu ---------
MSMEG_3934|M.smegmatis_MC2_155 ---------
MLBr_00955|M.leprae_Br4923 ---------