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EDQQPAAGDLTAEENPAADQNEATVAAAGDDRENGDAATESEAAKTSDAAPADGAEDSHSAETVETAGAA PAAGRRTKRLAGKAWAVAAMVAALLFVGSAGFAGAMVQPYLADRAVAATKLKVARTAANAITTLWTYTPE NMDTLADRASAYLSGDFEAQYRKFVDAIVAPNKQAKITNHTDVTGAAVESLDDTNAVVIVYTNTTSTSPL TKNVPSLKYLSYRLFMKRAKSRWLVTRMTTITSLDLTPKV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_5006 | - | - | 100% (251) | hypothetical protein MAV_5006 |
| M. avium 104 | MAV_0937 | - | 2e-17 | 29.63% (189) | hypothetical protein MAV_0937 |
| M. avium 104 | MAV_0955 | - | 4e-16 | 31.16% (199) | hypothetical protein MAV_0955 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0184 | - | 3e-79 | 62.95% (251) | mce associated membrane protein |
| M. gilvum PYR-GCK | Mflv_0702 | - | 2e-62 | 44.98% (309) | hypothetical protein Mflv_0702 |
| M. tuberculosis H37Rv | Rv0178 | - | 3e-79 | 62.95% (251) | mce associated membrane protein |
| M. leprae Br4923 | MLBr_02598 | - | 1e-76 | 77.47% (182) | putative secreted protein |
| M. abscessus ATCC 19977 | MAB_4146c | - | 4e-07 | 23.68% (152) | MCE-family protein |
| M. marinum M | MMAR_0421 | - | 1e-83 | 62.37% (279) | Mce associated membrane protein |
| M. smegmatis MC2 155 | MSMEG_0143 | - | 1e-59 | 50.00% (242) | mce associated membrane protein |
| M. thermoresistible (build 8) | TH_2075 | - | 2e-41 | 63.25% (117) | PROBABLE CONSERVED MCE ASSOCIATED MEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_1071 | - | 1e-84 | 63.70% (270) | Mce associated membrane protein |
| M. vanbaalenii PYR-1 | Mvan_0143 | - | 1e-64 | 49.81% (265) | hypothetical protein Mvan_0143 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0702|M.gilvum_PYR-GCK MEDQQPGSGDLTADAPAARPRRRFFGRRPKSADVEPVADTAVEDVAETVA
Mvan_0143|M.vanbaalenii_PYR-1 MEDQQPDPGDLT---------------------------TEVED------
MSMEG_0143|M.smegmatis_MC2_155 MEDQPADSGDLTTPARRRRWG----------FPLRRRQAEPAEQSDATGE
TH_2075|M.thermoresistible__bu --------------------------------------------------
Mb0184|M.bovis_AF2122/97 MEDQQSASGDLT--------------------------------------
Rv0178|M.tuberculosis_H37Rv MEDQQSASGDLT--------------------------------------
MAV_5006|M.avium_104 MEDQQPAAGDLT--------------------------------------
MLBr_02598|M.leprae_Br4923 --------------------------------------------------
MMAR_0421|M.marinum_M MEDQQPAAGDLTDAV-----------------------------------
MUL_1071|M.ulcerans_Agy99 MEDQQPAAGDLTDAV-----------------------------------
MAB_4146c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0702|M.gilvum_PYR-GCK EDAPKRPMGKGARAKAAVSENAETAPDLEAETPAAEADPAPADSEASEDE
Mvan_0143|M.vanbaalenii_PYR-1 ---PKVPVGKSRRTPKAQPQ--TQAPEADAEADAEPETDAEPDAEP-ETE
MSMEG_0143|M.smegmatis_MC2_155 GTEPSTEAGNESDAETKPRPVGKRQRTALSTGEQTAEDQTEETAGAAAYE
TH_2075|M.thermoresistible__bu --------------------------------------------------
Mb0184|M.bovis_AF2122/97 -------QKSVANGEST-----DTASAATEGHRGEIDAAGEPD---ERGA
Rv0178|M.tuberculosis_H37Rv -------QKSVANGEST-----DTASAATEGHRGEIDAAGEPD---ERGA
MAV_5006|M.avium_104 ----AEENPAADQNEAT----VAAAGDDRENGDAATESEAAKTSDAAPAD
MLBr_02598|M.leprae_Br4923 --------------------------------------------------
MMAR_0421|M.marinum_M SDGETEAAAAASDDEAQPDEAVQTPAAEAEPAEGAADDEATTDSVEDTGE
MUL_1071|M.ulcerans_Agy99 SDGETEAAAAASDDEAQPDEAVQTPAAGAEPAEGAADDEATTDSVEDTGE
MAB_4146c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0702|M.gilvum_PYR-GCK STPEVSEPEAT--EPQAEAEVEADPEPEP-VVMVPHRPAGRGVLIATAVA
Mvan_0143|M.vanbaalenii_PYR-1 GSADAEDTDDT--DLP-----DPAPEPEP-VVLVPHRPAGRKLVIAAAVA
MSMEG_0143|M.smegmatis_MC2_155 KPTETEESEVS--EPVAADEPADEDQPTQNIVFAPFRPAGKGLTYAAIAA
TH_2075|M.thermoresistible__bu --------------------------------------------------
Mb0184|M.bovis_AF2122/97 AVADSQADED--------DSAATAARGGKTR---ARRSRGRRLAITVGVA
Rv0178|M.tuberculosis_H37Rv AVADSQADED--------DSAATAARGGKTR---ARRSRGRRLAITVGVA
MAV_5006|M.avium_104 GAEDSHSAET-------VETAGAAPAAGRRT---KRLAG-KAWAVAAMVA
MLBr_02598|M.leprae_Br4923 --------------------MAAAEGGGSWR---NRRAG-QRTAIAVVVA
MMAR_0421|M.marinum_M ASADSTDPDTDADADADAEADGAKGKAAARRARPKRLTGRRLAAVGAAIT
MUL_1071|M.ulcerans_Agy99 ASADSTDPDT------DAEADGAKGKAAAR---PKRLTGRRLAAVGAAIT
MAB_4146c|M.abscessus_ATCC_199 --------------------------------------MRWLARIFVAVT
Mflv_0702|M.gilvum_PYR-GCK SVVFVGASGFAAAMAQPYLSERALVQTKLTIARTATDAITTLWSYTPEDM
Mvan_0143|M.vanbaalenii_PYR-1 SAVFVGASGFAAAMVQPYLVQRALVETKLNIARTATDAITTLWTYTPDDM
MSMEG_0143|M.smegmatis_MC2_155 ATLFVAAGAFAGATVWPYLSDRALVDTKVQVAQTSADAITTLWTYTPENI
TH_2075|M.thermoresistible__bu -----------------------------------------LWTYTPEDM
Mb0184|M.bovis_AF2122/97 AALFVGSAAFAGATVEPYLSERAVVATKLMVARTAANAITTLWTYTPENM
Rv0178|M.tuberculosis_H37Rv AALFVGSAAFAGATVEPYLSERAVVATKLMVARTAANAITTLWTYTPENM
MAV_5006|M.avium_104 ALLFVGSAGFAGAMVQPYLADRAVAATKLKVARTAANAITTLWTYTPENM
MLBr_02598|M.leprae_Br4923 AVLFVGSAAFAGAAVQPYLADRATVAVKLEVARTAANAITVLWTYTPENM
MMAR_0421|M.marinum_M ALLFVGSAAFAGAAVQPYLADRAVVAIKLNVARTAANAITTLWTYNPENM
MUL_1071|M.ulcerans_Agy99 ALLFVGSAAFAGAAVQPYLADRAVVAIKLNVARTAANAITTLWSYNPENM
MAB_4146c|M.abscessus_ATCC_199 VLVVVGLSAAAGGMYWHRVDTVASRAAGETLIKQAGKQIGSIFGYDYQTV
:: * : :
Mflv_0702|M.gilvum_PYR-GCK SSLAERASAYLTGDFAAEYRRYID-AIVEANKQAQVTNTTQVMGAAVESV
Mvan_0143|M.vanbaalenii_PYR-1 ATLADRASAYLDGDFAAEYRRYID-AIVEPNKQAQVTNTTQVMGAAVESV
MSMEG_0143|M.smegmatis_MC2_155 DTLPDRASRFLSNDFAAEYRQFID-SIVPSNKQAQITNNTQVVGTAVESI
TH_2075|M.thermoresistible__bu EDLPNRADKYLSGDFSDQYRRFID-AIVVSNKQSQVTNNTEVVGTAVESI
Mb0184|M.bovis_AF2122/97 DTLADRAANYLSGDFAAQYRRFVD-QIAAANKQAKITNDTEVTGAAVESL
Rv0178|M.tuberculosis_H37Rv DTLADRAANYLSGDFAAQYRRFVD-QIAAANKQAKITNDTEVTGAAVESL
MAV_5006|M.avium_104 DTLADRASAYLSGDFEAQYRKFVD-AIVAPNKQAKITNHTDVTGAAVESL
MLBr_02598|M.leprae_Br4923 DTLADRAATYVSGDFGAQYRKFVD-AIVGPNKQAKITNSTEVTGVAVESL
MMAR_0421|M.marinum_M DGLPDRAATYLSGDFGAQYRKFVD-TIVAPNKQAKITNNTEVTGVAVESL
MUL_1071|M.ulcerans_Agy99 DGLPDRAATYLSGDFGAQYRKFVD-TIVAPNKQAKITNNTEVTGVAVESL
MAB_4146c|M.abscessus_ATCC_199 ERSLDEQYAGLTPEYRREFEDKANREIIPQAKQRKIVSQTSIVGTGIIAA
:. : :: ::. : * ** ::.. *.: *..: :
Mflv_0702|M.gilvum_PYR-GCK SPPSIPTEATALVYTNSVATSPVTKNIPSLRYLSYRLTMNRDGGEWRITR
Mvan_0143|M.vanbaalenii_PYR-1 SPPTTPTEATALVYTNSVATSPVTKNIPSLRYLSYRLSLQRDGGDWRIVR
MSMEG_0143|M.smegmatis_MC2_155 S----ANEATAIVYTNSVSTSPVTKNVPSLRYLSYRLTLVRSDGDWRITQ
TH_2075|M.thermoresistible__bu S----PTEATAIVYTNSVATSPVTKNIPSLRYLSYRLTMERKNSEWLINR
Mb0184|M.bovis_AF2122/97 S----GRDAVAIVYTNTTTTSPVTKNIPALKYLSYRLFMKRYDARWLVTR
Rv0178|M.tuberculosis_H37Rv S----GRDAVAIVYTNTTTTSPVTKNIPALKYLSYRLFMKRYDARWLVTR
MAV_5006|M.avium_104 D----DTNAVVIVYTNTTSTSPLTKNVPSLKYLSYRLFMKRAKSRWLVTR
MLBr_02598|M.leprae_Br4923 D----ASNAIAIVYTNTTSTSPLTKNIPALKYLSYRLFMKRSAVRWLVTR
MMAR_0421|M.marinum_M D----GPNAIAIVYTNTTTTSPLTKNIPSMKYLSYRLIMKRDRSRWFVTR
MUL_1071|M.ulcerans_Agy99 D----GPNAIAIVYTNTTTTSPLTKNIPSMKYLSYRLIMKRDRSRWFVTR
MAB_4146c|M.abscessus_ATCC_199 H----RDSAQVVVYMNRTITD--QSRTPVYDSSSIQVDYTRAGDKWLISY
.* .:** * . *. .. * * :: * * :
Mflv_0702|M.gilvum_PYR-GCK MSTITSFDLTPQL
Mvan_0143|M.vanbaalenii_PYR-1 MSTITSFDLTPQL
MSMEG_0143|M.smegmatis_MC2_155 MPALTQLDLSPQL
TH_2075|M.thermoresistible__bu MTAITQLDLTPQL
Mb0184|M.bovis_AF2122/97 MTTITSLDLTPQV
Rv0178|M.tuberculosis_H37Rv MTTITSLDLTPQV
MAV_5006|M.avium_104 MTTITSLDLTPKV
MLBr_02598|M.leprae_Br4923 MTTITSLDLTPQL
MMAR_0421|M.marinum_M MTTITSLDLTPRV
MUL_1071|M.ulcerans_Agy99 MTTITSLDLTPRV
MAB_4146c|M.abscessus_ATCC_199 ITPL---------
:..: