For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VEDQPADSGDLTTPARRRRWGFPLRRRQAEPAEQSDATGEGTEPSTEAGNESDAETKPRPVGKRQRTALS TGEQTAEDQTEETAGAAAYEKPTETEESEVSEPVAADEPADEDQPTQNIVFAPFRPAGKGLTYAAIAAAT LFVAAGAFAGATVWPYLSDRALVDTKVQVAQTSADAITTLWTYTPENIDTLPDRASRFLSNDFAAEYRQF IDSIVPSNKQAQITNNTQVVGTAVESISANEATAIVYTNSVSTSPVTKNVPSLRYLSYRLTLVRSDGDWR ITQMPALTQLDLSPQL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0143 | - | - | 100% (296) | mce associated membrane protein |
| M. smegmatis MC2 155 | MSMEG_5207 | - | 3e-13 | 23.21% (224) | hypothetical protein MSMEG_5207 |
| M. smegmatis MC2 155 | MSMEG_4770 | - | 3e-11 | 27.44% (215) | hypothetical protein MSMEG_4770 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0184 | - | 9e-60 | 51.07% (233) | mce associated membrane protein |
| M. gilvum PYR-GCK | Mflv_0702 | - | 6e-74 | 49.20% (313) | hypothetical protein Mflv_0702 |
| M. tuberculosis H37Rv | Rv0178 | - | 9e-60 | 51.07% (233) | mce associated membrane protein |
| M. leprae Br4923 | MLBr_02598 | - | 1e-56 | 59.88% (172) | putative secreted protein |
| M. abscessus ATCC 19977 | MAB_4534c | - | 3e-07 | 23.31% (163) | hypothetical protein MAB_4534c |
| M. marinum M | MMAR_0421 | - | 4e-57 | 43.01% (279) | Mce associated membrane protein |
| M. avium 104 | MAV_5006 | - | 1e-59 | 50.00% (242) | hypothetical protein MAV_5006 |
| M. thermoresistible (build 8) | TH_2075 | - | 1e-45 | 70.94% (117) | PROBABLE CONSERVED MCE ASSOCIATED MEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_1071 | - | 4e-56 | 44.40% (268) | Mce associated membrane protein |
| M. vanbaalenii PYR-1 | Mvan_0143 | - | 3e-68 | 48.67% (300) | hypothetical protein Mvan_0143 |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_0143|M.smegmatis_MC2_155 MEDQPADSGDLTTPARRRRWGFPLRRRQAEPAEQSDATGEGTEPSTEAGN
TH_2075|M.thermoresistible__bu --------------------------------------------------
Mflv_0702|M.gilvum_PYR-GCK MEDQQPGSGDLTADAPAARPRRRFFGRRPKSADVEPVADTAVEDVAETVA
Mvan_0143|M.vanbaalenii_PYR-1 MEDQQPDPGDLT---------------------------TEVED------
MMAR_0421|M.marinum_M MEDQQPAAGDLTDAVSDG--------------------ETEAAAAASDDE
MUL_1071|M.ulcerans_Agy99 MEDQQPAAGDLTDAVSDG--------------------ETEAAAAASDDE
MLBr_02598|M.leprae_Br4923 --------------------------------------------------
MAV_5006|M.avium_104 MEDQQPAAGDLT---------------------------AEENPAADQNE
Mb0184|M.bovis_AF2122/97 MEDQQSASGDLT------------------------------QKSVANGE
Rv0178|M.tuberculosis_H37Rv MEDQQSASGDLT------------------------------QKSVANGE
MAB_4534c|M.abscessus_ATCC_199 MSRNMLR---------------------------------VILFDLLAPV
MSMEG_0143|M.smegmatis_MC2_155 ESDAETKPRPVGKRQRTALSTGEQTAEDQTEETAGAAAYEKPTETEESEV
TH_2075|M.thermoresistible__bu --------------------------------------------------
Mflv_0702|M.gilvum_PYR-GCK E-DAPKRPMGKGARAKAAVSENAETAPDLEAETPAAEADPAPADSEASED
Mvan_0143|M.vanbaalenii_PYR-1 ----PKVPVGKSRRTPKAQPQ--TQAPEADAEADAEPETDAEPDAEP-ET
MMAR_0421|M.marinum_M AQPDEAVQTPAAEAEPAEGAADDEATTDSVEDTGEASADSTDPDTDADAD
MUL_1071|M.ulcerans_Agy99 AQPDEAVQTPAAGAEPAEGAADDEATTDSVEDTGEASADSTDPDT-----
MLBr_02598|M.leprae_Br4923 --------------------------------------------------
MAV_5006|M.avium_104 AT----VAAAGDDRENGDAATESEAAKTSDAAPADGAEDSHSAET-----
Mb0184|M.bovis_AF2122/97 ST-----DTASAATEGHRGEIDAAGEPD---ERGAAVADSQADED-----
Rv0178|M.tuberculosis_H37Rv ST-----DTASAATEGHRGEIDAAGEPD---ERGAAVADSQADED-----
MAB_4534c|M.abscessus_ATCC_199 VTVLAIVELGVILRWPVWWVVVCTAVCVLIVEGMAVNAYLARRDS-----
MSMEG_0143|M.smegmatis_MC2_155 SEPVAADEPADEDQP----------TQNIVFAPFRPAG-KGLTYAAIAAA
TH_2075|M.thermoresistible__bu --------------------------------------------------
Mflv_0702|M.gilvum_PYR-GCK ESTPEVSEPEATEPQAEAEVEADPEPEPVVMVPHRPAG-RGVLIATAVAS
Mvan_0143|M.vanbaalenii_PYR-1 EGSADAEDTDDTDLP-----DPAPEPEPVVLVPHRPAG-RKLVIAAAVAS
MMAR_0421|M.marinum_M ADAEADGAKGKAAARR--------------ARPKRLTGRRLAAVGAAITA
MUL_1071|M.ulcerans_Agy99 -DAEADGAKGKAAAR-----------------PKRLTGRRLAAVGAAITA
MLBr_02598|M.leprae_Br4923 -----MAAAEGGGSW-----------------RNRRAG-QRTAIAVVVAA
MAV_5006|M.avium_104 --VETAGAAPAAGRR-----------------TKRLAG-KAWAVAAMVAA
Mb0184|M.bovis_AF2122/97 --DSAATAARGGKTR-----------------ARRSRG-RRLAITVGVAA
Rv0178|M.tuberculosis_H37Rv --DSAATAARGGKTR-----------------ARRSRG-RRLAITVGVAA
MAB_4534c|M.abscessus_ATCC_199 --VTVGTDDDGPALR---------------------TG----IVALATAS
MSMEG_0143|M.smegmatis_MC2_155 TLFVAAGAFAGATVWPYLSDRALVDTKVQVAQTSADAITTLWTYTPENID
TH_2075|M.thermoresistible__bu ----------------------------------------LWTYTPEDME
Mflv_0702|M.gilvum_PYR-GCK VVFVGASGFAAAMAQPYLSERALVQTKLTIARTATDAITTLWSYTPEDMS
Mvan_0143|M.vanbaalenii_PYR-1 AVFVGASGFAAAMVQPYLVQRALVETKLNIARTATDAITTLWTYTPDDMA
MMAR_0421|M.marinum_M LLFVGSAAFAGAAVQPYLADRAVVAIKLNVARTAANAITTLWTYNPENMD
MUL_1071|M.ulcerans_Agy99 LLFVGSAAFAGAAVQPYLADRAVVAIKLNVARTAANAITTLWSYNPENMD
MLBr_02598|M.leprae_Br4923 VLFVGSAAFAGAAVQPYLADRATVAVKLEVARTAANAITVLWTYTPENMD
MAV_5006|M.avium_104 LLFVGSAGFAGAMVQPYLADRAVAATKLKVARTAANAITTLWTYTPENMD
Mb0184|M.bovis_AF2122/97 ALFVGSAAFAGATVEPYLSERAVVATKLMVARTAANAITTLWTYTPENMD
Rv0178|M.tuberculosis_H37Rv ALFVGSAAFAGATVEPYLSERAVVATKLMVARTAANAITTLWTYTPENMD
MAB_4534c|M.abscessus_ATCC_199 VLAVAVVGYARWTLP----DREGNADRAAVTDVAATVSEAVVNFAPDNPD
: .: *::
MSMEG_0143|M.smegmatis_MC2_155 TLPDRASRFLSNDFAAEYRQFIDSIVPSNKQAQITNNTQVVGTAVESIS-
TH_2075|M.thermoresistible__bu DLPNRADKYLSGDFSDQYRRFIDAIVVSNKQSQVTNNTEVVGTAVESIS-
Mflv_0702|M.gilvum_PYR-GCK SLAERASAYLTGDFAAEYRRYIDAIVEANKQAQVTNTTQVMGAAVESVSP
Mvan_0143|M.vanbaalenii_PYR-1 TLADRASAYLDGDFAAEYRRYIDAIVEPNKQAQVTNTTQVMGAAVESVSP
MMAR_0421|M.marinum_M GLPDRAATYLSGDFGAQYRKFVDTIVAPNKQAKITNNTEVTGVAVESLD-
MUL_1071|M.ulcerans_Agy99 GLPDRAATYLSGDFGAQYRKFVDTIVAPNKQAKITNNTEVTGVAVESLD-
MLBr_02598|M.leprae_Br4923 TLADRAATYVSGDFGAQYRKFVDAIVGPNKQAKITNSTEVTGVAVESLD-
MAV_5006|M.avium_104 TLADRASAYLSGDFEAQYRKFVDAIVAPNKQAKITNHTDVTGAAVESLD-
Mb0184|M.bovis_AF2122/97 TLADRAANYLSGDFAAQYRRFVDQIAAANKQAKITNDTEVTGAAVESLS-
Rv0178|M.tuberculosis_H37Rv TLADRAANYLSGDFAAQYRRFVDQIAAANKQAKITNDTEVTGAAVESLS-
MAB_4534c|M.abscessus_ATCC_199 TSVRQATEHMTATQGQSFTRDFGRATAELKAKGISQQGEIVSVGIEALG-
:* .: .: : .. . * ::: :: ...:*::.
MSMEG_0143|M.smegmatis_MC2_155 ---ANEATAIVYTNSVSTSPVTKNVPSLRYLSYRLTLVRSDGDWRITQMP
TH_2075|M.thermoresistible__bu ---PTEATAIVYTNSVATSPVTKNIPSLRYLSYRLTMERKNSEWLINRMT
Mflv_0702|M.gilvum_PYR-GCK PSIPTEATALVYTNSVATSPVTKNIPSLRYLSYRLTMNRDGGEWRITRMS
Mvan_0143|M.vanbaalenii_PYR-1 PTTPTEATALVYTNSVATSPVTKNIPSLRYLSYRLSLQRDGGDWRIVRMS
MMAR_0421|M.marinum_M ---GPNAIAIVYTNTTTTSPLTKNIPSMKYLSYRLIMKRDRSRWFVTRMT
MUL_1071|M.ulcerans_Agy99 ---GPNAIAIVYTNTTTTSPLTKNIPSMKYLSYRLIMKRDRSRWFVTRMT
MLBr_02598|M.leprae_Br4923 ---ASNAIAIVYTNTTSTSPLTKNIPALKYLSYRLFMKRSAVRWLVTRMT
MAV_5006|M.avium_104 ---DTNAVVIVYTNTTSTSPLTKNVPSLKYLSYRLFMKRAKSRWLVTRMT
Mb0184|M.bovis_AF2122/97 ---GRDAVAIVYTNTTTTSPVTKNIPALKYLSYRLFMKRYDARWLVTRMT
Rv0178|M.tuberculosis_H37Rv ---GRDAVAIVYTNTTTTSPVTKNIPALKYLSYRLFMKRYDARWLVTRMT
MAB_4534c|M.abscessus_ATCC_199 ---PGDAVMATLVRRTSVAAKTR--PEQSVLALRLTLTKRDGRWLVDNIA
:* . .. .:.:. *: * *: ** : : * : .:.
MSMEG_0143|M.smegmatis_MC2_155 ALTQLDLSPQL-
TH_2075|M.thermoresistible__bu AITQLDLTPQL-
Mflv_0702|M.gilvum_PYR-GCK TITSFDLTPQL-
Mvan_0143|M.vanbaalenii_PYR-1 TITSFDLTPQL-
MMAR_0421|M.marinum_M TITSLDLTPRV-
MUL_1071|M.ulcerans_Agy99 TITSLDLTPRV-
MLBr_02598|M.leprae_Br4923 TITSLDLTPQL-
MAV_5006|M.avium_104 TITSLDLTPKV-
Mb0184|M.bovis_AF2122/97 TITSLDLTPQV-
Rv0178|M.tuberculosis_H37Rv TITSLDLTPQV-
MAB_4534c|M.abscessus_ATCC_199 PIDRIGAQVPKN
.: :.