For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
EDQQPGSGDLTADAPAARPRRRFFGRRPKSADVEPVADTAVEDVAETVAEDAPKRPMGKGARAKAAVSEN AETAPDLEAETPAAEADPAPADSEASEDESTPEVSEPEATEPQAEAEVEADPEPEPVVMVPHRPAGRGVL IATAVASVVFVGASGFAAAMAQPYLSERALVQTKLTIARTATDAITTLWSYTPEDMSSLAERASAYLTGD FAAEYRRYIDAIVEANKQAQVTNTTQVMGAAVESVSPPSIPTEATALVYTNSVATSPVTKNIPSLRYLSY RLTMNRDGGEWRITRMSTITSFDLTPQL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0702 | - | - | 100% (309) | hypothetical protein Mflv_0702 |
| M. gilvum PYR-GCK | Mflv_2527 | - | 2e-12 | 29.49% (217) | hypothetical protein Mflv_2527 |
| M. gilvum PYR-GCK | Mflv_2108 | - | 2e-10 | 26.05% (238) | hypothetical protein Mflv_2108 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0184 | - | 1e-59 | 46.27% (268) | mce associated membrane protein |
| M. tuberculosis H37Rv | Rv0178 | - | 1e-59 | 46.27% (268) | mce associated membrane protein |
| M. leprae Br4923 | MLBr_02598 | - | 8e-56 | 57.63% (177) | putative secreted protein |
| M. abscessus ATCC 19977 | MAB_4147c | - | 7e-06 | 27.23% (213) | MCE-family protein |
| M. marinum M | MMAR_0421 | - | 1e-63 | 43.61% (321) | Mce associated membrane protein |
| M. avium 104 | MAV_5006 | - | 2e-62 | 44.98% (309) | hypothetical protein MAV_5006 |
| M. smegmatis MC2 155 | MSMEG_0143 | - | 8e-74 | 49.20% (313) | mce associated membrane protein |
| M. thermoresistible (build 8) | TH_2075 | - | 1e-44 | 71.07% (121) | PROBABLE CONSERVED MCE ASSOCIATED MEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_1071 | - | 3e-63 | 43.59% (312) | Mce associated membrane protein |
| M. vanbaalenii PYR-1 | Mvan_0143 | - | 5e-97 | 64.24% (316) | hypothetical protein Mvan_0143 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0702|M.gilvum_PYR-GCK MEDQQPGSGDLTADAPAARPRRRFFGRRPKSADVEPVADTAVEDVAETVA
Mvan_0143|M.vanbaalenii_PYR-1 MEDQQPDPGDLT---------------------------TEVED------
MSMEG_0143|M.smegmatis_MC2_155 MEDQPADSGDLTTPARRRRWG----------FPLRRRQAEPAEQSDATGE
TH_2075|M.thermoresistible__bu --------------------------------------------------
MLBr_02598|M.leprae_Br4923 --------------------------------------------------
MAV_5006|M.avium_104 MEDQQPAAGDLT--------------------------------------
MMAR_0421|M.marinum_M MEDQQPAAGDLTDAV-----------------------------------
MUL_1071|M.ulcerans_Agy99 MEDQQPAAGDLTDAV-----------------------------------
Mb0184|M.bovis_AF2122/97 MEDQQSASGDLT--------------------------------------
Rv0178|M.tuberculosis_H37Rv MEDQQSASGDLT--------------------------------------
MAB_4147c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0702|M.gilvum_PYR-GCK EDAPKRPMGKGARAKAAVSENAETAPDLEAETPAAEADPAPADSEASEDE
Mvan_0143|M.vanbaalenii_PYR-1 ---PKVPVGKSRRTPKAQPQ--TQAPEADAEADAEPETDAEPDAEP-ETE
MSMEG_0143|M.smegmatis_MC2_155 GTEPSTEAGNESDAETKPRPVGKRQRTALSTGEQTAEDQTEETAGAAAYE
TH_2075|M.thermoresistible__bu --------------------------------------------------
MLBr_02598|M.leprae_Br4923 --------------------------------------------------
MAV_5006|M.avium_104 ----AEENPAADQNEAT----VAAAGDDRENGDAATESEAAKTSDAAPAD
MMAR_0421|M.marinum_M SDGETEAAAAASDDEAQPDEAVQTPAAEAEPAEGAADDEATTDSVEDTGE
MUL_1071|M.ulcerans_Agy99 SDGETEAAAAASDDEAQPDEAVQTPAAGAEPAEGAADDEATTDSVEDTGE
Mb0184|M.bovis_AF2122/97 -------QKSVANGEST-----DTASAATEGHRGEIDAAGEPD---ERGA
Rv0178|M.tuberculosis_H37Rv -------QKSVANGEST-----DTASAATEGHRGEIDAAGEPD---ERGA
MAB_4147c|M.abscessus_ATCC_199 -------------------------MTEEKKSASQTTRRRAARPAGPTGE
Mflv_0702|M.gilvum_PYR-GCK STPEVSEPEAT--EPQAEAEVEADPEPEP-VVMVPHRPAGRGVLIATAVA
Mvan_0143|M.vanbaalenii_PYR-1 GSADAEDTDDT--DLP-----DPAPEPEP-VVLVPHRPAGRKLVIAAAVA
MSMEG_0143|M.smegmatis_MC2_155 KPTETEESEVS--EPVAADEPADEDQPTQNIVFAPFRPAGKGLTYAAIAA
TH_2075|M.thermoresistible__bu --------------------------------------------------
MLBr_02598|M.leprae_Br4923 --------------------MAAAEGGGSWR---NRRAG-QRTAIAVVVA
MAV_5006|M.avium_104 GAEDSHSAET-------VETAGAAPAAGRRT---KRLAG-KAWAVAAMVA
MMAR_0421|M.marinum_M ASADSTDPDTDADADADAEADGAKGKAAARRARPKRLTGRRLAAVGAAIT
MUL_1071|M.ulcerans_Agy99 ASADSTDPDT------DAEADGAKGKAAAR---PKRLTGRRLAAVGAAIT
Mb0184|M.bovis_AF2122/97 AVADSQADED--------DSAATAARGGKTR---ARRSRGRRLAITVGVA
Rv0178|M.tuberculosis_H37Rv AVADSQADED--------DSAATAARGGKTR---ARRSRGRRLAITVGVA
MAB_4147c|M.abscessus_ATCC_199 VSAEPISVSLG--------RTEALSKPEPTVADSRRPGNTRGVLRAATVL
Mflv_0702|M.gilvum_PYR-GCK SVVFVGASGFAAAMAQPYLSERALVQTK-LTIARTATDAITTLWSYTPED
Mvan_0143|M.vanbaalenii_PYR-1 SAVFVGASGFAAAMVQPYLVQRALVETK-LNIARTATDAITTLWTYTPDD
MSMEG_0143|M.smegmatis_MC2_155 ATLFVAAGAFAGATVWPYLSDRALVDTK-VQVAQTSADAITTLWTYTPEN
TH_2075|M.thermoresistible__bu ------------------------------------------LWTYTPED
MLBr_02598|M.leprae_Br4923 AVLFVGSAAFAGAAVQPYLADRATVAVK-LEVARTAANAITVLWTYTPEN
MAV_5006|M.avium_104 ALLFVGSAGFAGAMVQPYLADRAVAATK-LKVARTAANAITTLWTYTPEN
MMAR_0421|M.marinum_M ALLFVGSAAFAGAAVQPYLADRAVVAIK-LNVARTAANAITTLWTYNPEN
MUL_1071|M.ulcerans_Agy99 ALLFVGSAAFAGAAVQPYLADRAVVAIK-LNVARTAANAITTLWSYNPEN
Mb0184|M.bovis_AF2122/97 AALFVGSAAFAGATVEPYLSERAVVATK-LMVARTAANAITTLWTYTPEN
Rv0178|M.tuberculosis_H37Rv AALFVGSAAFAGATVEPYLSERAVVATK-LMVARTAANAITTLWTYTPEN
MAB_4147c|M.abscessus_ATCC_199 VVVLVGALGVALALMGRAQHRDDLRAARDQRFVDTAVQTVTNMMTYSPDS
: :*.*:.
Mflv_0702|M.gilvum_PYR-GCK MSSLAERASAYLTGDFAAEYR-RYIDAIVEANKQAQVTNTTQVMGAAVES
Mvan_0143|M.vanbaalenii_PYR-1 MATLADRASAYLDGDFAAEYR-RYIDAIVEPNKQAQVTNTTQVMGAAVES
MSMEG_0143|M.smegmatis_MC2_155 IDTLPDRASRFLSNDFAAEYR-QFIDSIVPSNKQAQITNNTQVVGTAVES
TH_2075|M.thermoresistible__bu MEDLPNRADKYLSGDFSDQYR-RFIDAIVVSNKQSQVTNNTEVVGTAVES
MLBr_02598|M.leprae_Br4923 MDTLADRAATYVSGDFGAQYR-KFVDAIVGPNKQAKITNSTEVTGVAVES
MAV_5006|M.avium_104 MDTLADRASAYLSGDFEAQYR-KFVDAIVAPNKQAKITNHTDVTGAAVES
MMAR_0421|M.marinum_M MDGLPDRAATYLSGDFGAQYR-KFVDTIVAPNKQAKITNNTEVTGVAVES
MUL_1071|M.ulcerans_Agy99 MDGLPDRAATYLSGDFGAQYR-KFVDTIVAPNKQAKITNNTEVTGVAVES
Mb0184|M.bovis_AF2122/97 MDTLADRAANYLSGDFAAQYR-RFVDQIAAANKQAKITNDTEVTGAAVES
Rv0178|M.tuberculosis_H37Rv MDTLADRAANYLSGDFAAQYR-RFVDQIAAANKQAKITNDTEVTGAAVES
MAB_4147c|M.abscessus_ATCC_199 IDKNVDQFVNSTSGPLRGTFNPDNTANLKALYHQTGTSSEVVIKKASLES
: :: . : :. : :*: :. . : .::**
Mflv_0702|M.gilvum_PYR-GCK VSPPSIPTEATALVYTNSVATSPVTKNIPSLRYLSYRLTMNRDGGEWRIT
Mvan_0143|M.vanbaalenii_PYR-1 VSPPTTPTEATALVYTNSVATSPVTKNIPSLRYLSYRLSLQRDGGDWRIV
MSMEG_0143|M.smegmatis_MC2_155 IS----ANEATAIVYTNSVSTSPVTKNVPSLRYLSYRLTLVRSDGDWRIT
TH_2075|M.thermoresistible__bu IS----PTEATAIVYTNSVATSPVTKNIPSLRYLSYRLTMERKNSEWLIN
MLBr_02598|M.leprae_Br4923 LD----ASNAIAIVYTNTTSTSPLTKNIPALKYLSYRLFMKRSAVRWLVT
MAV_5006|M.avium_104 LD----DTNAVVIVYTNTTSTSPLTKNVPSLKYLSYRLFMKRAKSRWLVT
MMAR_0421|M.marinum_M LD----GPNAIAIVYTNTTTTSPLTKNIPSMKYLSYRLIMKRDRSRWFVT
MUL_1071|M.ulcerans_Agy99 LD----GPNAIAIVYTNTTTTSPLTKNIPSMKYLSYRLIMKRDRSRWFVT
Mb0184|M.bovis_AF2122/97 LS----GRDAVAIVYTNTTTTSPVTKNIPALKYLSYRLFMKRYDARWLVT
Rv0178|M.tuberculosis_H37Rv LS----GRDAVAIVYTNTTTTSPVTKNIPALKYLSYRLFMKRYDARWLVT
MAB_4147c|M.abscessus_ATCC_199 ID----EVSKKASILISARVTLTNADSGVNEPSKSYRMRMIVAEDQQGNM
:. . . : .: * . :.. ***: :
Mflv_0702|M.gilvum_PYR-GCK RMSTITSFDLTPQL
Mvan_0143|M.vanbaalenii_PYR-1 RMSTITSFDLTPQL
MSMEG_0143|M.smegmatis_MC2_155 QMPALTQLDLSPQL
TH_2075|M.thermoresistible__bu RMTAITQLDLTPQL
MLBr_02598|M.leprae_Br4923 RMTTITSLDLTPQL
MAV_5006|M.avium_104 RMTTITSLDLTPKV
MMAR_0421|M.marinum_M RMTTITSLDLTPRV
MUL_1071|M.ulcerans_Agy99 RMTTITSLDLTPRV
Mb0184|M.bovis_AF2122/97 RMTTITSLDLTPQV
Rv0178|M.tuberculosis_H37Rv RMTTITSLDLTPQV
MAB_4147c|M.abscessus_ATCC_199 TAYDLRWPDGQS--
: * .