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VEDQQSASGDLTQKSVANGESTDTASAATEGHRGEIDAAGEPDERGAAVADSQADEDDSAATAARGGKTR ARRSRGRRLAITVGVAAALFVGSAAFAGATVEPYLSERAVVATKLMVARTAANAITTLWTYTPENMDTLA DRAANYLSGDFAAQYRRFVDQIAAANKQAKITNDTEVTGAAVESLSGRDAVAIVYTNTTTTSPVTKNIPA LKYLSYRLFMKRYDARWLVTRMTTITSLDLTPQV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0184 | - | - | 100% (244) | mce associated membrane protein |
| M. bovis AF2122 / 97 | Mb1397c | - | 2e-14 | 29.78% (225) | hypothetical protein Mb1397c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0702 | - | 9e-60 | 46.27% (268) | hypothetical protein Mflv_0702 |
| M. tuberculosis H37Rv | Rv0178 | - | 1e-133 | 100.00% (244) | mce associated membrane protein |
| M. leprae Br4923 | MLBr_02598 | - | 7e-75 | 76.92% (182) | putative secreted protein |
| M. abscessus ATCC 19977 | MAB_4534c | - | 1e-08 | 27.49% (171) | hypothetical protein MAB_4534c |
| M. marinum M | MMAR_0421 | - | 5e-78 | 59.64% (275) | Mce associated membrane protein |
| M. avium 104 | MAV_5006 | - | 4e-79 | 62.95% (251) | hypothetical protein MAV_5006 |
| M. smegmatis MC2 155 | MSMEG_0143 | - | 1e-59 | 51.07% (233) | mce associated membrane protein |
| M. thermoresistible (build 8) | TH_2075 | - | 9e-42 | 64.96% (117) | PROBABLE CONSERVED MCE ASSOCIATED MEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_1071 | - | 3e-78 | 60.53% (266) | Mce associated membrane protein |
| M. vanbaalenii PYR-1 | Mvan_0143 | - | 2e-61 | 49.81% (265) | hypothetical protein Mvan_0143 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0702|M.gilvum_PYR-GCK MEDQQPGSGDLTADAPAARPRRRFFGRRPKSADVEPVADTAVEDVAETVA
Mvan_0143|M.vanbaalenii_PYR-1 MEDQQPDPGDLT---------------------------TEVED------
MSMEG_0143|M.smegmatis_MC2_155 MEDQPADSGDLTTPARRRRWG----------FPLRRRQAEPAEQSDATGE
TH_2075|M.thermoresistible__bu --------------------------------------------------
Mb0184|M.bovis_AF2122/97 MEDQQSASGDLT--------------------------------------
Rv0178|M.tuberculosis_H37Rv MEDQQSASGDLT--------------------------------------
MMAR_0421|M.marinum_M MEDQQPAAGDLTDAV-----------------------------------
MUL_1071|M.ulcerans_Agy99 MEDQQPAAGDLTDAV-----------------------------------
MLBr_02598|M.leprae_Br4923 --------------------------------------------------
MAV_5006|M.avium_104 MEDQQPAAGDLT--------------------------------------
MAB_4534c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0702|M.gilvum_PYR-GCK EDAPKRPMGKGARAKAAVSENAETAPDLEAETPAAEADPAPADSEASEDE
Mvan_0143|M.vanbaalenii_PYR-1 ---PKVPVGKSRRTPKAQPQ--TQAPEADAEADAEPETDAEPDAEP-ETE
MSMEG_0143|M.smegmatis_MC2_155 GTEPSTEAGNESDAETKPRPVGKRQRTALSTGEQTAEDQTEETAGAAAYE
TH_2075|M.thermoresistible__bu --------------------------------------------------
Mb0184|M.bovis_AF2122/97 -------QKSVANGEST-----DTASAATEGHRGEIDAAGEPD---ERGA
Rv0178|M.tuberculosis_H37Rv -------QKSVANGEST-----DTASAATEGHRGEIDAAGEPD---ERGA
MMAR_0421|M.marinum_M SDGETEAAAAASDDEAQPDEAVQTPAAEAEPAEGAADDEATTDSVEDTGE
MUL_1071|M.ulcerans_Agy99 SDGETEAAAAASDDEAQPDEAVQTPAAGAEPAEGAADDEATTDSVEDTGE
MLBr_02598|M.leprae_Br4923 --------------------------------------------------
MAV_5006|M.avium_104 ----AEENPAADQNEAT----VAAAGDDRENGDAATESEAAKTSDAAPAD
MAB_4534c|M.abscessus_ATCC_199 -------MSRNMLRVILFDLLAPVVTVLAIVELGVILRWPVWWVVVCTAV
Mflv_0702|M.gilvum_PYR-GCK STPEVSEPEAT-EPQAEAEVEADPEPEP-VVMVPHRPAG-RGVLIATAVA
Mvan_0143|M.vanbaalenii_PYR-1 GSADAEDTDDT-DLP-----DPAPEPEP-VVLVPHRPAG-RKLVIAAAVA
MSMEG_0143|M.smegmatis_MC2_155 KPTETEESEVS-EPVAADEPADEDQPTQNIVFAPFRPAG-KGLTYAAIAA
TH_2075|M.thermoresistible__bu --------------------------------------------------
Mb0184|M.bovis_AF2122/97 AVADSQADED-------DSAATAARGGKTR---ARRSRG-RRLAITVGVA
Rv0178|M.tuberculosis_H37Rv AVADSQADED-------DSAATAARGGKTR---ARRSRG-RRLAITVGVA
MMAR_0421|M.marinum_M ASADSTDPDTDADADADAEADGAKGKAAARRARPKRLTGRRLAAVGAAIT
MUL_1071|M.ulcerans_Agy99 ASADSTDPDT------DAEADGAKGKAAAR---PKRLTGRRLAAVGAAIT
MLBr_02598|M.leprae_Br4923 --------------------MAAAEGGGSW---RNRRAG-QRTAIAVVVA
MAV_5006|M.avium_104 GAEDSHSAET-------VETAGAAPAAGRR---TKRLAG-KAWAVAAMVA
MAB_4534c|M.abscessus_ATCC_199 CVLIVEGMAVN---------AYLARRDSVTVGTDDDGPALRTGIVALATA
Mflv_0702|M.gilvum_PYR-GCK SVVFVGASGFAAAMAQPYLSERALVQTKLTIARTATDAITTLWSYTPEDM
Mvan_0143|M.vanbaalenii_PYR-1 SAVFVGASGFAAAMVQPYLVQRALVETKLNIARTATDAITTLWTYTPDDM
MSMEG_0143|M.smegmatis_MC2_155 ATLFVAAGAFAGATVWPYLSDRALVDTKVQVAQTSADAITTLWTYTPENI
TH_2075|M.thermoresistible__bu -----------------------------------------LWTYTPEDM
Mb0184|M.bovis_AF2122/97 AALFVGSAAFAGATVEPYLSERAVVATKLMVARTAANAITTLWTYTPENM
Rv0178|M.tuberculosis_H37Rv AALFVGSAAFAGATVEPYLSERAVVATKLMVARTAANAITTLWTYTPENM
MMAR_0421|M.marinum_M ALLFVGSAAFAGAAVQPYLADRAVVAIKLNVARTAANAITTLWTYNPENM
MUL_1071|M.ulcerans_Agy99 ALLFVGSAAFAGAAVQPYLADRAVVAIKLNVARTAANAITTLWSYNPENM
MLBr_02598|M.leprae_Br4923 AVLFVGSAAFAGAAVQPYLADRATVAVKLEVARTAANAITVLWTYTPENM
MAV_5006|M.avium_104 ALLFVGSAGFAGAMVQPYLADRAVAATKLKVARTAANAITTLWTYTPENM
MAB_4534c|M.abscessus_ATCC_199 SVLAVAVVGYARWTLP----DREGNADRAAVTDVAATVSEAVVNFAPDNP
: .: *::
Mflv_0702|M.gilvum_PYR-GCK SSLAERASAYLTGDFAAEYRRYIDAIVEANKQAQVTNTTQVMGAAVESVS
Mvan_0143|M.vanbaalenii_PYR-1 ATLADRASAYLDGDFAAEYRRYIDAIVEPNKQAQVTNTTQVMGAAVESVS
MSMEG_0143|M.smegmatis_MC2_155 DTLPDRASRFLSNDFAAEYRQFIDSIVPSNKQAQITNNTQVVGTAVESIS
TH_2075|M.thermoresistible__bu EDLPNRADKYLSGDFSDQYRRFIDAIVVSNKQSQVTNNTEVVGTAVESIS
Mb0184|M.bovis_AF2122/97 DTLADRAANYLSGDFAAQYRRFVDQIAAANKQAKITNDTEVTGAAVESLS
Rv0178|M.tuberculosis_H37Rv DTLADRAANYLSGDFAAQYRRFVDQIAAANKQAKITNDTEVTGAAVESLS
MMAR_0421|M.marinum_M DGLPDRAATYLSGDFGAQYRKFVDTIVAPNKQAKITNNTEVTGVAVESLD
MUL_1071|M.ulcerans_Agy99 DGLPDRAATYLSGDFGAQYRKFVDTIVAPNKQAKITNNTEVTGVAVESLD
MLBr_02598|M.leprae_Br4923 DTLADRAATYVSGDFGAQYRKFVDAIVGPNKQAKITNSTEVTGVAVESLD
MAV_5006|M.avium_104 DTLADRASAYLSGDFEAQYRKFVDAIVAPNKQAKITNHTDVTGAAVESLD
MAB_4534c|M.abscessus_ATCC_199 DTSVRQATEHMTATQGQSFTRDFGRATAELKAKGISQQGEIVSVGIEALG
:* .: .: : .. . * ::: :: ...:*::.
Mflv_0702|M.gilvum_PYR-GCK PPSIPTEATALVYTNSVATSPVTKNIPSLRYLSYRLTMNRDGGEWRITRM
Mvan_0143|M.vanbaalenii_PYR-1 PPTTPTEATALVYTNSVATSPVTKNIPSLRYLSYRLSLQRDGGDWRIVRM
MSMEG_0143|M.smegmatis_MC2_155 ----ANEATAIVYTNSVSTSPVTKNVPSLRYLSYRLTLVRSDGDWRITQM
TH_2075|M.thermoresistible__bu ----PTEATAIVYTNSVATSPVTKNIPSLRYLSYRLTMERKNSEWLINRM
Mb0184|M.bovis_AF2122/97 ----GRDAVAIVYTNTTTTSPVTKNIPALKYLSYRLFMKRYDARWLVTRM
Rv0178|M.tuberculosis_H37Rv ----GRDAVAIVYTNTTTTSPVTKNIPALKYLSYRLFMKRYDARWLVTRM
MMAR_0421|M.marinum_M ----GPNAIAIVYTNTTTTSPLTKNIPSMKYLSYRLIMKRDRSRWFVTRM
MUL_1071|M.ulcerans_Agy99 ----GPNAIAIVYTNTTTTSPLTKNIPSMKYLSYRLIMKRDRSRWFVTRM
MLBr_02598|M.leprae_Br4923 ----ASNAIAIVYTNTTSTSPLTKNIPALKYLSYRLFMKRSAVRWLVTRM
MAV_5006|M.avium_104 ----DTNAVVIVYTNTTSTSPLTKNVPSLKYLSYRLFMKRAKSRWLVTRM
MAB_4534c|M.abscessus_ATCC_199 ----PGDAVMATLVRRTSVAAKTR--PEQSVLALRLTLTKRDGRWLVDNI
:* . .. .:.:. *: * *: ** : : * : .:
Mflv_0702|M.gilvum_PYR-GCK STITSFDLTPQL-
Mvan_0143|M.vanbaalenii_PYR-1 STITSFDLTPQL-
MSMEG_0143|M.smegmatis_MC2_155 PALTQLDLSPQL-
TH_2075|M.thermoresistible__bu TAITQLDLTPQL-
Mb0184|M.bovis_AF2122/97 TTITSLDLTPQV-
Rv0178|M.tuberculosis_H37Rv TTITSLDLTPQV-
MMAR_0421|M.marinum_M TTITSLDLTPRV-
MUL_1071|M.ulcerans_Agy99 TTITSLDLTPRV-
MLBr_02598|M.leprae_Br4923 TTITSLDLTPQL-
MAV_5006|M.avium_104 TTITSLDLTPKV-
MAB_4534c|M.abscessus_ATCC_199 APIDRIGAQVPKN
..: :.