For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VEDQQPDPGDLTTEVEDPKVPVGKSRRTPKAQPQTQAPEADAEADAEPETDAEPDAEPETEGSADAEDTD DTDLPDPAPEPEPVVLVPHRPAGRKLVIAAAVASAVFVGASGFAAAMVQPYLVQRALVETKLNIARTATD AITTLWTYTPDDMATLADRASAYLDGDFAAEYRRYIDAIVEPNKQAQVTNTTQVMGAAVESVSPPTTPTE ATALVYTNSVATSPVTKNIPSLRYLSYRLSLQRDGGDWRIVRMSTITSFDLTPQL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0143 | - | - | 100% (265) | hypothetical protein Mvan_0143 |
| M. vanbaalenii PYR-1 | Mvan_4597 | - | 2e-11 | 26.92% (260) | hypothetical protein Mvan_4597 |
| M. vanbaalenii PYR-1 | Mvan_4131 | - | 5e-10 | 27.68% (224) | twin-arginine translocation pathway signal |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0184 | - | 1e-61 | 49.81% (265) | mce associated membrane protein |
| M. gilvum PYR-GCK | Mflv_0702 | - | 4e-97 | 64.24% (316) | hypothetical protein Mflv_0702 |
| M. tuberculosis H37Rv | Rv0178 | - | 1e-61 | 49.81% (265) | mce associated membrane protein |
| M. leprae Br4923 | MLBr_02598 | - | 1e-56 | 58.19% (177) | putative secreted protein |
| M. abscessus ATCC 19977 | MAB_4593c | - | 2e-07 | 20.97% (248) | hypothetical protein MAB_4593c |
| M. marinum M | MMAR_0421 | - | 9e-65 | 48.01% (277) | Mce associated membrane protein |
| M. avium 104 | MAV_5006 | - | 1e-64 | 49.81% (265) | hypothetical protein MAV_5006 |
| M. smegmatis MC2 155 | MSMEG_0143 | - | 3e-68 | 48.67% (300) | mce associated membrane protein |
| M. thermoresistible (build 8) | TH_2075 | - | 5e-43 | 68.60% (121) | PROBABLE CONSERVED MCE ASSOCIATED MEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_1071 | - | 6e-65 | 49.26% (270) | Mce associated membrane protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0143|M.vanbaalenii_PYR-1 MEDQQPDPGDLT---------------------------TEVED------
Mflv_0702|M.gilvum_PYR-GCK MEDQQPGSGDLTADAPAARPRRRFFGRRPKSADVEPVADTAVEDVAETVA
MSMEG_0143|M.smegmatis_MC2_155 MEDQPADSGDLTTPARRRRWG----------FPLRRRQAEPAEQSDATGE
TH_2075|M.thermoresistible__bu --------------------------------------------------
MMAR_0421|M.marinum_M MEDQQPAAGDLTDAV-----------------------------------
MUL_1071|M.ulcerans_Agy99 MEDQQPAAGDLTDAV-----------------------------------
Mb0184|M.bovis_AF2122/97 MEDQQSASGDLT--------------------------------------
Rv0178|M.tuberculosis_H37Rv MEDQQSASGDLT--------------------------------------
MLBr_02598|M.leprae_Br4923 --------------------------------------------------
MAV_5006|M.avium_104 MEDQQPAAGDLT--------------------------------------
MAB_4593c|M.abscessus_ATCC_199 MADDAADKDAKN--------------------------------------
Mvan_0143|M.vanbaalenii_PYR-1 ---PKVPVGKSRRTPKAQPQ--TQAPEADAEADAEPETDAEPDAEP-ETE
Mflv_0702|M.gilvum_PYR-GCK EDAPKRPMGKGARAKAAVSENAETAPDLEAETPAAEADPAPADSEASEDE
MSMEG_0143|M.smegmatis_MC2_155 GTEPSTEAGNESDAETKPRPVGKRQRTALSTGEQTAEDQTEETAGAAAYE
TH_2075|M.thermoresistible__bu --------------------------------------------------
MMAR_0421|M.marinum_M SDGETEAAAAASDDEAQPDEAVQTPAAEAEPAEGAADDEATTDSVEDTGE
MUL_1071|M.ulcerans_Agy99 SDGETEAAAAASDDEAQPDEAVQTPAAGAEPAEGAADDEATTDSVEDTGE
Mb0184|M.bovis_AF2122/97 ----QKSVANGESTDT----ASAATEGHRGEIDAAGEPDER-------GA
Rv0178|M.tuberculosis_H37Rv ----QKSVANGESTDT----ASAATEGHRGEIDAAGEPDER-------GA
MLBr_02598|M.leprae_Br4923 --------------------------------------------------
MAV_5006|M.avium_104 ----AEENPAADQNEA----TVAAAGDDRENGDAATESEAAKTSDAAPAD
MAB_4593c|M.abscessus_ATCC_199 ---ADESAVTSDAEKAESSAPSSAAVESTAEGTTEAATAEVADFDAEDSE
Mvan_0143|M.vanbaalenii_PYR-1 GSADAEDTDDTDLP-----DPAPEPEP-VVLVP-HRPAGRKLVIA-AAVA
Mflv_0702|M.gilvum_PYR-GCK STPEVSEPEATEPQAEAEVEADPEPEP-VVMVP-HRPAGRGVLIA-TAVA
MSMEG_0143|M.smegmatis_MC2_155 KPTETEESEVSEPVAADEPADEDQPTQNIVFAP-FRPAGKGLTYA-AIAA
TH_2075|M.thermoresistible__bu --------------------------------------------------
MMAR_0421|M.marinum_M ASADSTDPDTDADADADAEADGAKGKAAARRARPKRLTGRRLAAVGAAIT
MUL_1071|M.ulcerans_Agy99 ASADSTDPDT------DAEADGAKGKAAAR---PKRLTGRRLAAVGAAIT
Mb0184|M.bovis_AF2122/97 AVADSQADED------DSAATAARGGKTRA----RRSRGRRLAIT-VGVA
Rv0178|M.tuberculosis_H37Rv AVADSQADED------DSAATAARGGKTRA----RRSRGRRLAIT-VGVA
MLBr_02598|M.leprae_Br4923 -------------------MAAAEGGGSWR----NRRAGQRTAIA-VVVA
MAV_5006|M.avium_104 GAEDSHSAET------VETAGAAPAAGRRT----KRLAGKAWAVA-AMVA
MAB_4593c|M.abscessus_ATCC_199 KTKDSGAVEDS-----DDEDISLEPDEEEN---PKRIRGRHWALTAAAIV
Mvan_0143|M.vanbaalenii_PYR-1 SAVFVGASGFAAAMVQPYLVQRALVETKLNIARTATDAITTLWTYTPDDM
Mflv_0702|M.gilvum_PYR-GCK SVVFVGASGFAAAMAQPYLSERALVQTKLTIARTATDAITTLWSYTPEDM
MSMEG_0143|M.smegmatis_MC2_155 ATLFVAAGAFAGATVWPYLSDRALVDTKVQVAQTSADAITTLWTYTPENI
TH_2075|M.thermoresistible__bu -----------------------------------------LWTYTPEDM
MMAR_0421|M.marinum_M ALLFVGSAAFAGAAVQPYLADRAVVAIKLNVARTAANAITTLWTYNPENM
MUL_1071|M.ulcerans_Agy99 ALLFVGSAAFAGAAVQPYLADRAVVAIKLNVARTAANAITTLWSYNPENM
Mb0184|M.bovis_AF2122/97 AALFVGSAAFAGATVEPYLSERAVVATKLMVARTAANAITTLWTYTPENM
Rv0178|M.tuberculosis_H37Rv AALFVGSAAFAGATVEPYLSERAVVATKLMVARTAANAITTLWTYTPENM
MLBr_02598|M.leprae_Br4923 AVLFVGSAAFAGAAVQPYLADRATVAVKLEVARTAANAITVLWTYTPENM
MAV_5006|M.avium_104 ALLFVGSAGFAGAMVQPYLADRAVAATKLKVARTAANAITTLWTYTPENM
MAB_4593c|M.abscessus_ATCC_199 AIAIVALAAIIGRLYEEQRIEEQSSREALAAAQEFAN---VMINVDSAKL
: . . .:
Mvan_0143|M.vanbaalenii_PYR-1 ATLADRASAYLDGDFAAEYRRYIDAIVEPNKQAQVTNTTQVMGAAVESVS
Mflv_0702|M.gilvum_PYR-GCK SSLAERASAYLTGDFAAEYRRYIDAIVEANKQAQVTNTTQVMGAAVESVS
MSMEG_0143|M.smegmatis_MC2_155 DTLPDRASRFLSNDFAAEYRQFIDSIVPSNKQAQITNNTQVVGTAVESIS
TH_2075|M.thermoresistible__bu EDLPNRADKYLSGDFSDQYRRFIDAIVVSNKQSQVTNNTEVVGTAVESIS
MMAR_0421|M.marinum_M DGLPDRAATYLSGDFGAQYRKFVDTIVAPNKQAKITNNTEVTGVAVESLD
MUL_1071|M.ulcerans_Agy99 DGLPDRAATYLSGDFGAQYRKFVDTIVAPNKQAKITNNTEVTGVAVESLD
Mb0184|M.bovis_AF2122/97 DTLADRAANYLSGDFAAQYRRFVDQIAAANKQAKITNDTEVTGAAVESLS
Rv0178|M.tuberculosis_H37Rv DTLADRAANYLSGDFAAQYRRFVDQIAAANKQAKITNDTEVTGAAVESLS
MLBr_02598|M.leprae_Br4923 DTLADRAATYVSGDFGAQYRKFVDAIVGPNKQAKITNSTEVTGVAVESLD
MAV_5006|M.avium_104 DTLADRASAYLSGDFEAQYRKFVDAIVAPNKQAKITNHTDVTGAAVESLD
MAB_4593c|M.abscessus_ATCC_199 DESSNKTLERSTGDFKQKYSESSTTLRQVMIENKAKATGVVVDSAVKSAA
.::: .** :* . : : : . * . **:*
Mvan_0143|M.vanbaalenii_PYR-1 PPTTPTEATALVYTNSVATSPVTKNIPSLRYLSYRLSLQRDGGDWRIVRM
Mflv_0702|M.gilvum_PYR-GCK PPSIPTEATALVYTNSVATSPVTKNIPSLRYLSYRLTMNRDGGEWRITRM
MSMEG_0143|M.smegmatis_MC2_155 ----ANEATAIVYTNSVSTSPVTKNVPSLRYLSYRLTLVRSDGDWRITQM
TH_2075|M.thermoresistible__bu ----PTEATAIVYTNSVATSPVTKNIPSLRYLSYRLTMERKNSEWLINRM
MMAR_0421|M.marinum_M ----GPNAIAIVYTNTTTTSPLTKNIPSMKYLSYRLIMKRDRSRWFVTRM
MUL_1071|M.ulcerans_Agy99 ----GPNAIAIVYTNTTTTSPLTKNIPSMKYLSYRLIMKRDRSRWFVTRM
Mb0184|M.bovis_AF2122/97 ----GRDAVAIVYTNTTTTSPVTKNIPALKYLSYRLFMKRYDARWLVTRM
Rv0178|M.tuberculosis_H37Rv ----GRDAVAIVYTNTTTTSPVTKNIPALKYLSYRLFMKRYDARWLVTRM
MLBr_02598|M.leprae_Br4923 ----ASNAIAIVYTNTTSTSPLTKNIPALKYLSYRLFMKRSAVRWLVTRM
MAV_5006|M.avium_104 ----DTNAVVIVYTNTTSTSPLTKNVPSLKYLSYRLFMKRAKSRWLVTRM
MAB_4593c|M.abscessus_ATCC_199 -----PDKVEVLLFIDQAVSNVAIPDARMDRSRVQITMQKVDGRWLAS--
: :: :.* :: . : :: : : *
Mvan_0143|M.vanbaalenii_PYR-1 STITSFDLTPQL
Mflv_0702|M.gilvum_PYR-GCK STITSFDLTPQL
MSMEG_0143|M.smegmatis_MC2_155 PALTQLDLSPQL
TH_2075|M.thermoresistible__bu TAITQLDLTPQL
MMAR_0421|M.marinum_M TTITSLDLTPRV
MUL_1071|M.ulcerans_Agy99 TTITSLDLTPRV
Mb0184|M.bovis_AF2122/97 TTITSLDLTPQV
Rv0178|M.tuberculosis_H37Rv TTITSLDLTPQV
MLBr_02598|M.leprae_Br4923 TTITSLDLTPQL
MAV_5006|M.avium_104 TTITSLDLTPKV
MAB_4593c|M.abscessus_ATCC_199 ----DVELT---
..:*: