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M. thermoresistible (build 8) TH_2075 ()

annotation: PROBABLE CONSERVED MCE ASSOCIATED MEMBRANE PROTEIN
coordinates: 4064431 - 4064784
length: 118

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2075-100% (118)PROBABLE CONSERVED MCE ASSOCIATED MEMBRANE PROTEIN
M. thermoresistible (build 8)TH_2500-7e-1027.10% (107) PUTATIVE putative conserved hypothetical protein
M. thermoresistible (build 8)TH_3191-1e-0828.16% (103) PUTATIVE twin-arginine translocation pathway signal

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0184-2e-4264.96% (117) mce associated membrane protein
M. gilvum PYR-GCKMflv_0702-4e-4571.07% (121) hypothetical protein Mflv_0702
M. tuberculosis H37RvRv0178-2e-4264.96% (117) mce associated membrane protein
M. leprae Br4923MLBr_02598-2e-4164.10% (117) putative secreted protein
M. abscessus ATCC 19977MAB_4534c-2e-0519.44% (108) hypothetical protein MAB_4534c
M. marinum MMMAR_0421-2e-4163.25% (117) Mce associated membrane protein
M. avium 104MAV_5006-6e-4263.25% (117) hypothetical protein MAV_5006
M. smegmatis MC2 155MSMEG_0143-4e-4670.94% (117) mce associated membrane protein
M. ulcerans Agy99MUL_1071-5e-4162.39% (117) Mce associated membrane protein
M. vanbaalenii PYR-1Mvan_0143-2e-4368.60% (121) hypothetical protein Mvan_0143

CLUSTAL 2.0.9 multiple sequence alignment


TH_2075|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0143|M.smegmatis_MC2_155      MEDQPADSGDLTTPARRRRWGFPLRRRQAEPAEQSDATGEGTEPSTEAGN
Mflv_0702|M.gilvum_PYR-GCK          MEDQQPGSGDLTADAPAARPRRRFFGRRPKSADVEPVADTAVEDVAETVA
Mvan_0143|M.vanbaalenii_PYR-1       MEDQQPDPGDLT---------------------------TEVED------
MMAR_0421|M.marinum_M               MEDQQPAAGDLTDAVSDG--------------------ETEAAAAASDDE
MUL_1071|M.ulcerans_Agy99           MEDQQPAAGDLTDAVSDG--------------------ETEAAAAASDDE
MLBr_02598|M.leprae_Br4923          --------------------------------------------------
MAV_5006|M.avium_104                MEDQQPAAGDLT---------------------------AEENPAADQNE
Mb0184|M.bovis_AF2122/97            MEDQQSASGDLT------------------------------QKSVANGE
Rv0178|M.tuberculosis_H37Rv         MEDQQSASGDLT------------------------------QKSVANGE
MAB_4534c|M.abscessus_ATCC_199      MSRNMLR---------------------------------VILFDLLAPV
                                                                                      

TH_2075|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0143|M.smegmatis_MC2_155      ESDAETKPRPVGKRQRTALSTGEQTAEDQTEETAGAAAYEKPTETEESEV
Mflv_0702|M.gilvum_PYR-GCK          E-DAPKRPMGKGARAKAAVSENAETAPDLEAETPAAEADPAPADSEASED
Mvan_0143|M.vanbaalenii_PYR-1       ----PKVPVGKSRRTPKAQPQ--TQAPEADAEADAEPETDAEPDAEP-ET
MMAR_0421|M.marinum_M               AQPDEAVQTPAAEAEPAEGAADDEATTDSVEDTGEASADSTDPDTDADAD
MUL_1071|M.ulcerans_Agy99           AQPDEAVQTPAAGAEPAEGAADDEATTDSVEDTGEASADSTDPDT-----
MLBr_02598|M.leprae_Br4923          --------------------------------------------------
MAV_5006|M.avium_104                AT----VAAAGDDRENGDAATESEAAKTSDAAPADGAEDSHSAET-----
Mb0184|M.bovis_AF2122/97            ST-----DTASAATEGHRGEIDAAGEPD---ERGAAVADSQADED-----
Rv0178|M.tuberculosis_H37Rv         ST-----DTASAATEGHRGEIDAAGEPD---ERGAAVADSQADED-----
MAB_4534c|M.abscessus_ATCC_199      VTVLAIVELGVILRWPVWWVVVCTAVCVLIVEGMAVNAYLARRDS-----
                                                                                      

TH_2075|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0143|M.smegmatis_MC2_155      SEPVAADEPADEDQP----------TQNIVFAPFRPAG-KGLTYAAIAAA
Mflv_0702|M.gilvum_PYR-GCK          ESTPEVSEPEATEPQAEAEVEADPEPEPVVMVPHRPAG-RGVLIATAVAS
Mvan_0143|M.vanbaalenii_PYR-1       EGSADAEDTDDTDLP-----DPAPEPEPVVLVPHRPAG-RKLVIAAAVAS
MMAR_0421|M.marinum_M               ADAEADGAKGKAAARR--------------ARPKRLTGRRLAAVGAAITA
MUL_1071|M.ulcerans_Agy99           -DAEADGAKGKAAAR-----------------PKRLTGRRLAAVGAAITA
MLBr_02598|M.leprae_Br4923          -----MAAAEGGGSW-----------------RNRRAG-QRTAIAVVVAA
MAV_5006|M.avium_104                --VETAGAAPAAGRR-----------------TKRLAG-KAWAVAAMVAA
Mb0184|M.bovis_AF2122/97            --DSAATAARGGKTR-----------------ARRSRG-RRLAITVGVAA
Rv0178|M.tuberculosis_H37Rv         --DSAATAARGGKTR-----------------ARRSRG-RRLAITVGVAA
MAB_4534c|M.abscessus_ATCC_199      --VTVGTDDDGPALR---------------------TG----IVALATAS
                                                                                      

TH_2075|M.thermoresistible__bu      ----------------------------------------LWTYTPEDME
MSMEG_0143|M.smegmatis_MC2_155      TLFVAAGAFAGATVWPYLSDRALVDTKVQVAQTSADAITTLWTYTPENID
Mflv_0702|M.gilvum_PYR-GCK          VVFVGASGFAAAMAQPYLSERALVQTKLTIARTATDAITTLWSYTPEDMS
Mvan_0143|M.vanbaalenii_PYR-1       AVFVGASGFAAAMVQPYLVQRALVETKLNIARTATDAITTLWTYTPDDMA
MMAR_0421|M.marinum_M               LLFVGSAAFAGAAVQPYLADRAVVAIKLNVARTAANAITTLWTYNPENMD
MUL_1071|M.ulcerans_Agy99           LLFVGSAAFAGAAVQPYLADRAVVAIKLNVARTAANAITTLWSYNPENMD
MLBr_02598|M.leprae_Br4923          VLFVGSAAFAGAAVQPYLADRATVAVKLEVARTAANAITVLWTYTPENMD
MAV_5006|M.avium_104                LLFVGSAGFAGAMVQPYLADRAVAATKLKVARTAANAITTLWTYTPENMD
Mb0184|M.bovis_AF2122/97            ALFVGSAAFAGATVEPYLSERAVVATKLMVARTAANAITTLWTYTPENMD
Rv0178|M.tuberculosis_H37Rv         ALFVGSAAFAGATVEPYLSERAVVATKLMVARTAANAITTLWTYTPENMD
MAB_4534c|M.abscessus_ATCC_199      VLAVAVVGYARWTLP----DREGNADRAAVTDVAATVSEAVVNFAPDNPD
                                                                            : .: *::  

TH_2075|M.thermoresistible__bu      DLPNRADKYLSGDFSDQYRRFIDAIVVSNKQSQVTNNTEVVGTAVESIS-
MSMEG_0143|M.smegmatis_MC2_155      TLPDRASRFLSNDFAAEYRQFIDSIVPSNKQAQITNNTQVVGTAVESIS-
Mflv_0702|M.gilvum_PYR-GCK          SLAERASAYLTGDFAAEYRRYIDAIVEANKQAQVTNTTQVMGAAVESVSP
Mvan_0143|M.vanbaalenii_PYR-1       TLADRASAYLDGDFAAEYRRYIDAIVEPNKQAQVTNTTQVMGAAVESVSP
MMAR_0421|M.marinum_M               GLPDRAATYLSGDFGAQYRKFVDTIVAPNKQAKITNNTEVTGVAVESLD-
MUL_1071|M.ulcerans_Agy99           GLPDRAATYLSGDFGAQYRKFVDTIVAPNKQAKITNNTEVTGVAVESLD-
MLBr_02598|M.leprae_Br4923          TLADRAATYVSGDFGAQYRKFVDAIVGPNKQAKITNSTEVTGVAVESLD-
MAV_5006|M.avium_104                TLADRASAYLSGDFEAQYRKFVDAIVAPNKQAKITNHTDVTGAAVESLD-
Mb0184|M.bovis_AF2122/97            TLADRAANYLSGDFAAQYRRFVDQIAAANKQAKITNDTEVTGAAVESLS-
Rv0178|M.tuberculosis_H37Rv         TLADRAANYLSGDFAAQYRRFVDQIAAANKQAKITNDTEVTGAAVESLS-
MAB_4534c|M.abscessus_ATCC_199      TSVRQATEHMTATQGQSFTRDFGRATAELKAKGISQQGEIVSVGIEALG-
                                        :*  .:      .: : ..  .   *   :::  :: ...:*::. 

TH_2075|M.thermoresistible__bu      ---PTEATAIVYTNSVATSPVTKNIPSLRYLSYRLTMERKNSEWLINRMT
MSMEG_0143|M.smegmatis_MC2_155      ---ANEATAIVYTNSVSTSPVTKNVPSLRYLSYRLTLVRSDGDWRITQMP
Mflv_0702|M.gilvum_PYR-GCK          PSIPTEATALVYTNSVATSPVTKNIPSLRYLSYRLTMNRDGGEWRITRMS
Mvan_0143|M.vanbaalenii_PYR-1       PTTPTEATALVYTNSVATSPVTKNIPSLRYLSYRLSLQRDGGDWRIVRMS
MMAR_0421|M.marinum_M               ---GPNAIAIVYTNTTTTSPLTKNIPSMKYLSYRLIMKRDRSRWFVTRMT
MUL_1071|M.ulcerans_Agy99           ---GPNAIAIVYTNTTTTSPLTKNIPSMKYLSYRLIMKRDRSRWFVTRMT
MLBr_02598|M.leprae_Br4923          ---ASNAIAIVYTNTTSTSPLTKNIPALKYLSYRLFMKRSAVRWLVTRMT
MAV_5006|M.avium_104                ---DTNAVVIVYTNTTSTSPLTKNVPSLKYLSYRLFMKRAKSRWLVTRMT
Mb0184|M.bovis_AF2122/97            ---GRDAVAIVYTNTTTTSPVTKNIPALKYLSYRLFMKRYDARWLVTRMT
Rv0178|M.tuberculosis_H37Rv         ---GRDAVAIVYTNTTTTSPVTKNIPALKYLSYRLFMKRYDARWLVTRMT
MAB_4534c|M.abscessus_ATCC_199      ---PGDAVMATLVRRTSVAAKTR--PEQSVLALRLTLTKRDGRWLVDNIA
                                         :*   . .. .:.:. *:  *    *: ** : :    * : .:.

TH_2075|M.thermoresistible__bu      AITQLDLTPQL-
MSMEG_0143|M.smegmatis_MC2_155      ALTQLDLSPQL-
Mflv_0702|M.gilvum_PYR-GCK          TITSFDLTPQL-
Mvan_0143|M.vanbaalenii_PYR-1       TITSFDLTPQL-
MMAR_0421|M.marinum_M               TITSLDLTPRV-
MUL_1071|M.ulcerans_Agy99           TITSLDLTPRV-
MLBr_02598|M.leprae_Br4923          TITSLDLTPQL-
MAV_5006|M.avium_104                TITSLDLTPKV-
Mb0184|M.bovis_AF2122/97            TITSLDLTPQV-
Rv0178|M.tuberculosis_H37Rv         TITSLDLTPQV-
MAB_4534c|M.abscessus_ATCC_199      PIDRIGAQVPKN
                                    .:  :.