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VAAAEGGGSWRNRRAGQRTAIAVVVAAVLFVGSAAFAGAAVQPYLADRATVAVKLEVARTAANAITVLWT YTPENMDTLADRAATYVSGDFGAQYRKFVDAIVGPNKQAKITNSTEVTGVAVESLDASNAIAIVYTNTTS TSPLTKNIPALKYLSYRLFMKRSAVRWLVTRMTTITSLDLTPQL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_02598 | - | - | 100% (184) | putative secreted protein |
| M. leprae Br4923 | MLBr_02615 | - | 3e-05 | 28.12% (160) | hypothetical protein MLBr_02615 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0184 | - | 1e-74 | 76.92% (182) | mce associated membrane protein |
| M. gilvum PYR-GCK | Mflv_0702 | - | 1e-55 | 57.63% (177) | hypothetical protein Mflv_0702 |
| M. tuberculosis H37Rv | Rv0178 | - | 1e-74 | 76.92% (182) | mce associated membrane protein |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_0421 | - | 2e-74 | 79.77% (173) | Mce associated membrane protein |
| M. avium 104 | MAV_5006 | - | 2e-76 | 77.47% (182) | hypothetical protein MAV_5006 |
| M. smegmatis MC2 155 | MSMEG_0143 | - | 2e-56 | 59.88% (172) | mce associated membrane protein |
| M. thermoresistible (build 8) | TH_2075 | - | 1e-40 | 64.10% (117) | PROBABLE CONSERVED MCE ASSOCIATED MEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_1071 | - | 3e-74 | 76.50% (183) | Mce associated membrane protein |
| M. vanbaalenii PYR-1 | Mvan_0143 | - | 2e-56 | 58.19% (177) | hypothetical protein Mvan_0143 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0184|M.bovis_AF2122/97 MEDQQSASGDLT--------------------------------------
Rv0178|M.tuberculosis_H37Rv MEDQQSASGDLT--------------------------------------
MLBr_02598|M.leprae_Br4923 --------------------------------------------------
MAV_5006|M.avium_104 MEDQQPAAGDLT--------------------------------------
MMAR_0421|M.marinum_M MEDQQPAAGDLTDAV-----------------------------------
MUL_1071|M.ulcerans_Agy99 MEDQQPAAGDLTDAV-----------------------------------
Mflv_0702|M.gilvum_PYR-GCK MEDQQPGSGDLTADAPAARPRRRFFGRRPKSADVEPVADTAVEDVAETVA
Mvan_0143|M.vanbaalenii_PYR-1 MEDQQPDPGDLT---------------------------TEVED------
MSMEG_0143|M.smegmatis_MC2_155 MEDQPADSGDLTTPARRRRWGFPLRRRQAEPAEQSDATGEGTEPSTEAGN
TH_2075|M.thermoresistible__bu --------------------------------------------------
Mb0184|M.bovis_AF2122/97 --------QKSVANGEST-----DTASAATEGHRGEIDAAGEPD---ERG
Rv0178|M.tuberculosis_H37Rv --------QKSVANGEST-----DTASAATEGHRGEIDAAGEPD---ERG
MLBr_02598|M.leprae_Br4923 --------------------------------------------------
MAV_5006|M.avium_104 -----AEENPAADQNEAT----VAAAGDDRENGDAATESEAAKTSDAAPA
MMAR_0421|M.marinum_M -SDGETEAAAAASDDEAQPDEAVQTPAAEAEPAEGAADDEATTDSVEDTG
MUL_1071|M.ulcerans_Agy99 -SDGETEAAAAASDDEAQPDEAVQTPAAGAEPAEGAADDEATTDSVEDTG
Mflv_0702|M.gilvum_PYR-GCK E-DAPKRPMGKGARAKAAVSENAETAPDLEAETPAAEADPAPADSEASED
Mvan_0143|M.vanbaalenii_PYR-1 ----PKVPVGKSRRTPKAQPQ--TQAPEADAEADAEPETDAEPDAEP-ET
MSMEG_0143|M.smegmatis_MC2_155 ESDAETKPRPVGKRQRTALSTGEQTAEDQTEETAGAAAYEKPTETEESEV
TH_2075|M.thermoresistible__bu --------------------------------------------------
Mb0184|M.bovis_AF2122/97 AAVADSQADED--------DSAATAARGGKTR---ARRSRGRRLAITVGV
Rv0178|M.tuberculosis_H37Rv AAVADSQADED--------DSAATAARGGKTR---ARRSRGRRLAITVGV
MLBr_02598|M.leprae_Br4923 ---------------------MAAAEGGGSWR---NRRAG-QRTAIAVVV
MAV_5006|M.avium_104 DGAEDSHSAET-------VETAGAAPAAGRRT---KRLAG-KAWAVAAMV
MMAR_0421|M.marinum_M EASADSTDPDTDADADADAEADGAKGKAAARRARPKRLTGRRLAAVGAAI
MUL_1071|M.ulcerans_Agy99 EASADSTDPDT------DAEADGAKGKAAAR---PKRLTGRRLAAVGAAI
Mflv_0702|M.gilvum_PYR-GCK ESTPEVSEPEATEPQAEAEVEADPEPEPVVMVP--HRPAG-RGVLIATAV
Mvan_0143|M.vanbaalenii_PYR-1 EGSADAEDTDDTDLP-----DPAPEPEPVVLVP--HRPAG-RKLVIAAAV
MSMEG_0143|M.smegmatis_MC2_155 SEPVAADEPADEDQP----------TQNIVFAP--FRPAG-KGLTYAAIA
TH_2075|M.thermoresistible__bu --------------------------------------------------
Mb0184|M.bovis_AF2122/97 AAALFVGSAAFAGATVEPYLSERAVVATKLMVARTAANAITTLWTYTPEN
Rv0178|M.tuberculosis_H37Rv AAALFVGSAAFAGATVEPYLSERAVVATKLMVARTAANAITTLWTYTPEN
MLBr_02598|M.leprae_Br4923 AAVLFVGSAAFAGAAVQPYLADRATVAVKLEVARTAANAITVLWTYTPEN
MAV_5006|M.avium_104 AALLFVGSAGFAGAMVQPYLADRAVAATKLKVARTAANAITTLWTYTPEN
MMAR_0421|M.marinum_M TALLFVGSAAFAGAAVQPYLADRAVVAIKLNVARTAANAITTLWTYNPEN
MUL_1071|M.ulcerans_Agy99 TALLFVGSAAFAGAAVQPYLADRAVVAIKLNVARTAANAITTLWSYNPEN
Mflv_0702|M.gilvum_PYR-GCK ASVVFVGASGFAAAMAQPYLSERALVQTKLTIARTATDAITTLWSYTPED
Mvan_0143|M.vanbaalenii_PYR-1 ASAVFVGASGFAAAMVQPYLVQRALVETKLNIARTATDAITTLWTYTPDD
MSMEG_0143|M.smegmatis_MC2_155 AATLFVAAGAFAGATVWPYLSDRALVDTKVQVAQTSADAITTLWTYTPEN
TH_2075|M.thermoresistible__bu ------------------------------------------LWTYTPED
**:*.*::
Mb0184|M.bovis_AF2122/97 MDTLADRAANYLSGDFAAQYRRFVDQIAAANKQAKITNDTEVTGAAVESL
Rv0178|M.tuberculosis_H37Rv MDTLADRAANYLSGDFAAQYRRFVDQIAAANKQAKITNDTEVTGAAVESL
MLBr_02598|M.leprae_Br4923 MDTLADRAATYVSGDFGAQYRKFVDAIVGPNKQAKITNSTEVTGVAVESL
MAV_5006|M.avium_104 MDTLADRASAYLSGDFEAQYRKFVDAIVAPNKQAKITNHTDVTGAAVESL
MMAR_0421|M.marinum_M MDGLPDRAATYLSGDFGAQYRKFVDTIVAPNKQAKITNNTEVTGVAVESL
MUL_1071|M.ulcerans_Agy99 MDGLPDRAATYLSGDFGAQYRKFVDTIVAPNKQAKITNNTEVTGVAVESL
Mflv_0702|M.gilvum_PYR-GCK MSSLAERASAYLTGDFAAEYRRYIDAIVEANKQAQVTNTTQVMGAAVESV
Mvan_0143|M.vanbaalenii_PYR-1 MATLADRASAYLDGDFAAEYRRYIDAIVEPNKQAQVTNTTQVMGAAVESV
MSMEG_0143|M.smegmatis_MC2_155 IDTLPDRASRFLSNDFAAEYRQFIDSIVPSNKQAQITNNTQVVGTAVESI
TH_2075|M.thermoresistible__bu MEDLPNRADKYLSGDFSDQYRRFIDAIVVSNKQSQVTNNTEVVGTAVESI
: *.:** :: .** :**:::* *. .***:::** *:* *.****:
Mb0184|M.bovis_AF2122/97 S----GRDAVAIVYTNTTTTSPVTKNIPALKYLSYRLFMKRYDARWLVTR
Rv0178|M.tuberculosis_H37Rv S----GRDAVAIVYTNTTTTSPVTKNIPALKYLSYRLFMKRYDARWLVTR
MLBr_02598|M.leprae_Br4923 D----ASNAIAIVYTNTTSTSPLTKNIPALKYLSYRLFMKRSAVRWLVTR
MAV_5006|M.avium_104 D----DTNAVVIVYTNTTSTSPLTKNVPSLKYLSYRLFMKRAKSRWLVTR
MMAR_0421|M.marinum_M D----GPNAIAIVYTNTTTTSPLTKNIPSMKYLSYRLIMKRDRSRWFVTR
MUL_1071|M.ulcerans_Agy99 D----GPNAIAIVYTNTTTTSPLTKNIPSMKYLSYRLIMKRDRSRWFVTR
Mflv_0702|M.gilvum_PYR-GCK SPPSIPTEATALVYTNSVATSPVTKNIPSLRYLSYRLTMNRDGGEWRITR
Mvan_0143|M.vanbaalenii_PYR-1 SPPTTPTEATALVYTNSVATSPVTKNIPSLRYLSYRLSLQRDGGDWRIVR
MSMEG_0143|M.smegmatis_MC2_155 S----ANEATAIVYTNSVSTSPVTKNVPSLRYLSYRLTLVRSDGDWRITQ
TH_2075|M.thermoresistible__bu S----PTEATAIVYTNSVATSPVTKNIPSLRYLSYRLTMERKNSEWLINR
. :* .:****:.:***:***:*:::****** : * * : :
Mb0184|M.bovis_AF2122/97 MTTITSLDLTPQV
Rv0178|M.tuberculosis_H37Rv MTTITSLDLTPQV
MLBr_02598|M.leprae_Br4923 MTTITSLDLTPQL
MAV_5006|M.avium_104 MTTITSLDLTPKV
MMAR_0421|M.marinum_M MTTITSLDLTPRV
MUL_1071|M.ulcerans_Agy99 MTTITSLDLTPRV
Mflv_0702|M.gilvum_PYR-GCK MSTITSFDLTPQL
Mvan_0143|M.vanbaalenii_PYR-1 MSTITSFDLTPQL
MSMEG_0143|M.smegmatis_MC2_155 MPALTQLDLSPQL
TH_2075|M.thermoresistible__bu MTAITQLDLTPQL
*.::*.:**:*::