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M. avium 104 MAV_0872 (-)

annotation: DNA-binding response regulator, LuxR family protein
coordinates: 816986 - 817537
length: 183

NVVGEAEDGSAALELIKSHQPDVALLDYRMPGMDGAQVAAAVRADGLATRVLLISAHDESAIVYQALQQG
AAGFVLKDSTRSEIVKAVLDCAQGRDVVAPALVGGLAAEIRQRAEPTGPVLSAREREVLHRIARGQSIPA
IAGELYVAPSTVKTHVQRLYEKLGVSDRAAAVAEAMRQGLLS*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_0872--100% (183)DNA-binding response regulator, LuxR family protein
M. avium 104MAV_4114-5e-2939.67% (184) response regulator receiver domain-containing protein
M. avium 104MAV_5280-2e-2637.30% (185) two-component system response regulator

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0867cnarL2e-8387.91% (182) nitrate/nitrite response transcriptional regulatory protein
M. gilvum PYR-GCKMflv_0730-2e-7073.63% (182) two component LuxR family transcriptional regulator
M. tuberculosis H37RvRv0844cnarL5e-8488.46% (182) nitrate/nitrite response transcriptional regulatory protein
M. leprae Br4923MLBr_01286-1e-1131.82% (88) putative two-component response regulatory protein
M. abscessus ATCC 19977MAB_0060-3e-7172.53% (182) nitrate/nitrite response transcriptional regulatory protein
M. marinum MMMAR_4782narL7e-8790.11% (182) nitrate/nitrite response regulator protein NarL
M. smegmatis MC2 155MSMEG_0105-1e-7075.27% (182) DNA-binding response regulator, LuxR family protein
M. thermoresistible (build 8)TH_3563-5e-2837.63% (186) PUTATIVE DNA-binding response regulator, LuxR family protein
M. ulcerans Agy99MUL_0351narL2e-8790.11% (182) nitrate/nitrite response regulator protein NarL
M. vanbaalenii PYR-1Mvan_2836-3e-2737.36% (182) two component LuxR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mb0867c|M.bovis_AF2122/97           -----MSNPQPEKVRVVVGDDHPLFREGVVRALSLSGSVNVVGEADDGAA
Rv0844c|M.tuberculosis_H37Rv        -----MSNPQPEKVRVVVGDDHPLFREGVVRALSLSGSVNVVGEADDGAA
MMAR_4782|M.marinum_M               -----MDVTKTEKVRVVVGDDHPLFREGVVRALSLSGSVNVVGEADDGAA
MUL_0351|M.ulcerans_Agy99           -----MDVTKTEKVRVVVGDDHPLFREGVVRALSLSGSVNVVGEADDGAA
MAV_0872|M.avium_104                --------------------------------------MNVVGEAEDGSA
Mflv_0730|M.gilvum_PYR-GCK          -------MTGPGRVRVVVGDDHPMFRDGVVRALQSSGAIDVVAEADDGTA
MSMEG_0105|M.smegmatis_MC2_155      -----MLTRMSDKVRVVVGDDHPMFREGVVRALTSSGDIDVVAEADNGAD
MAB_0060|M.abscessus_ATCC_1997      -----MQVSG-ELVRVVVGDDHPLFREGVVRALTASGQITVVAEAENGTG
TH_3563|M.thermoresistible__bu      -------MGEPQQPTVMVVDDHPIWREAVARDLAEAG-LSVVATADGVAA
Mvan_2836|M.vanbaalenii_PYR-1       ---------------MMVVDDHPIWRDAVARDLADDG-FDVVATADGVAS
MLBr_01286|M.leprae_Br4923          MTGPTTDADAATPHRVLIAEDEALIRLDLAEMLRDEG-YDIVGEAADGQE
                                                                            :*. * .   

Mb0867c|M.bovis_AF2122/97           ALELIKAHLPDVALLDYRMPGMDGAQVPAAVRSYELPTRVLLISAHDEPA
Rv0844c|M.tuberculosis_H37Rv        ALELIKAHLPDVALLDYRMPGMDGAQVAAAVRSYELPTRVLLISAHDEPA
MMAR_4782|M.marinum_M               ALELIKTHLPDVALLDYRMPRMDGAQVAAAVRSNELPTRVLLISAHDESA
MUL_0351|M.ulcerans_Agy99           ALELIETHLPDVALLDYRMPRMDGAQVAAAVRSNGLPTRVLLISAHDESA
MAV_0872|M.avium_104                ALELIKSHQPDVALLDYRMPGMDGAQVAAAVRADGLATRVLLISAHDESA
Mflv_0730|M.gilvum_PYR-GCK          ALAAIREHRPAVALLDYRMPGMDGAEVAAAVQRGALPTRVLLISAHDESA
MSMEG_0105|M.smegmatis_MC2_155      ALELIKVHRPAVALLDYRMPQLDGAQVAAAVVRDELPTRVLLVSAHDESA
MAB_0060|M.abscessus_ATCC_1997      ALELIREHRPDVALVDYRMPELDGTQVAAAVRRDELPTRVLLLSAHDDAA
TH_3563|M.thermoresistible__bu      ARRRAAAVRPDVVLMDMRLPDGDGARATAEVRAVSPDSRVLVLSASEERD
Mvan_2836|M.vanbaalenii_PYR-1       AKRRAAVVQPAVVLMDMRLADGDGAQATAEVLAVSPSSRVLVLSASDERD
MLBr_01286|M.leprae_Br4923          AVELAERHKPDLVIMDVKMPRRDGIDAASEIASKRIAP-IVVLTAFSQRD
                                    *        * :.::* ::.  **  ..: :      . :::::* .:  

Mb0867c|M.bovis_AF2122/97           IVYQALQQGAAGFLLKDSTRTEIVKAVLDCAKGRDVVAPSLVGGLAGEIR
Rv0844c|M.tuberculosis_H37Rv        IVYQALQQGAAGFLLKDSTRTEIVKAVLDCAKGRDVVAPSLVGGLAGEIR
MMAR_4782|M.marinum_M               IVYQALQQGAAGFLLKDSTRTEIVKAVLDCAKGRDVVAPSLVGGLAGEIR
MUL_0351|M.ulcerans_Agy99           IVYQALQQGAAGFLLKDSTRTEIVKAVLDCAKGRDVVAPSLVGGLAGEIR
MAV_0872|M.avium_104                IVYQALQQGAAGFVLKDSTRSEIVKAVLDCAQGRDVVAPALVGGLAAEIR
Mflv_0730|M.gilvum_PYR-GCK          IVYRALADGAAGFLPKESTRNELITAVLDCAKGRDVVAPSLAAGLAGEIR
MSMEG_0105|M.smegmatis_MC2_155      IVYSALQQGAAGFLSKESTRSELVSAVLSCAKGRDVITPHLAAGLAGEIR
MAB_0060|M.abscessus_ATCC_1997      IVYRALEEGAAGFLSKESTRTELVGAVLDCARGRDVVAASLTAGLAGEIR
TH_3563|M.thermoresistible__bu      DVLEAVKAGATGYLVKSASKTELVDAVHATAQGRAVFTPGLAGLVLGEYR
Mvan_2836|M.vanbaalenii_PYR-1       DVLEAVKAGATGYLVKSASKQELGDAVRATAQGRAVFTPGLAGLVLGEFR
MLBr_01286|M.leprae_Br4923          LVERARDAGAMAYLVKPFTISDLIPAIALAMSRFSELT-----ALEREVA
                                     *  *   ** .:: *  :  ::  *:         .:      :  *  

Mb0867c|M.bovis_AF2122/97           --QRAAPVA---PVLSAREREVLNRIACGQSIPAIAAELYVAPSTVKTHV
Rv0844c|M.tuberculosis_H37Rv        --QRAAPVA---PVLSAREREVLNRIACGQSIPAIAAELYVAPSTVKTHV
MMAR_4782|M.marinum_M               --QRAAPMA---PVLSAREREVLHRIAKGQSIPAIAGELYVAPSTVKTHV
MUL_0351|M.ulcerans_Agy99           --QRAAPMA---PVLSAREREVLHRIAKGQSIPAIAGELYVAPSTVKTHV
MAV_0872|M.avium_104                --QRAEPTG---PVLSAREREVLHRIARGQSIPAIAGELYVAPSTVKTHV
Mflv_0730|M.gilvum_PYR-GCK          --RRAEPEG---PALSPREREVLVLIAAGSTIPAMARELFLAPSTVKTHV
MSMEG_0105|M.smegmatis_MC2_155      --RRNEPDV---PVLSPREREVLNLIAQGRSIPAMAKELYLAPSTVKTHV
MAB_0060|M.abscessus_ATCC_1997      --KRAQPAG---PSLSTREREVLRMIAAGQTVPAIARALFLAPSTVKTHV
TH_3563|M.thermoresistible__bu      RISRQPGAGPDAPRLTERETEILRYVAKGLTAKQIAAQLSLSHRTVENHV
Mvan_2836|M.vanbaalenii_PYR-1       RIERDSPAG---PTLTERETEILRHVAKGLTAKQIASRLSLSHRTVENHV
MLBr_01286|M.leprae_Br4923          -------------TLADR-LETRKLVERAKGLLQVKQGMTEPEAFKWIQR
                                                  *: *  *    :  .     :   :  .      : 

Mb0867c|M.bovis_AF2122/97           QRLYEKLGVSDRAAAVAEAMRQRLLD
Rv0844c|M.tuberculosis_H37Rv        QRLYEKLGVSDRAAAVAEAMRQRLLD
MMAR_4782|M.marinum_M               QRLYEKLGVSDRAAAVAEAMRQGLLD
MUL_0351|M.ulcerans_Agy99           QRLYEKLGVSDRAAAVAEAMRQGLLD
MAV_0872|M.avium_104                QRLYEKLGVSDRAAAVAEAMRQGLLS
Mflv_0730|M.gilvum_PYR-GCK          QRLYEKLGVSDRGAAVAEAMRRKLLD
MSMEG_0105|M.smegmatis_MC2_155      QRLYEKLGVSDRAAAVAEAMRRHLLD
MAB_0060|M.abscessus_ATCC_1997      QRLYEKLGVGDRAAAVAEAMRRGLLE
TH_3563|M.thermoresistible__bu      QATFRKLQVANRVELARYAIEHGLDE
Mvan_2836|M.vanbaalenii_PYR-1       QATFRKLQIGNRVELARYAIEHGLDE
MLBr_01286|M.leprae_Br4923          AAMDRRTTMKRVAEVVLETLDTPKDT
                                        .:  :      .  ::