For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TTATGSVGRASDHPALLEARAAHSRAEWAAAYQAYLRAEAIGPMTLDDLDAYATTAWRLGHSREAVRLAE RVYGQLVRRDPATAATKAVDIALEWLTRGDLNIAQGWMNRARRLLTGAPTGPTHCYLAYLDVVLAVAEQD PEELARRAEAVRHLCDSVEDPALESLSLVSQAIAALHQGRVADGYALVDEALLPLLAGHVRVEWAGDIYC VVLNLCHKLADHPRMRAWTQSMERWCDVHSASPFYRVCDVHRLQLAAADDDYRRLEDQLFSASTALEDVN SWVGAEGFYQLGEVRRLRGDTEGALAAFAKARSLGKDPQPGEALLHCSVGQSRKAWTDLRVALAGAGPLD RMRLLRAAVVVALARDDIGEAQRYCDQLAAGAEAFATPGYRGWAAHARGAVLVRRGEFEAALDNLGAALR EYRLQQERYDIAEVYEWMALAHRGLGDDTAADTDIATAENIYEQLAVQPSGVCGRASPGGLTRREIEVLR AIAGGATNRQVAHQFVISDKTVGRHLANIYTKLGVSSRTAAVTWAYQNGVVRKDN*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4339 | - | - | 100% (546) | TPR repeat-containing protein |
| M. smegmatis MC2 155 | MSMEG_1901 | - | 1e-11 | 28.67% (293) | DNA-binding HTH domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_1494 | - | 3e-10 | 47.54% (61) | transcriptional regulatory protein DegU |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0393 | - | 2e-11 | 23.12% (532) | LuxR/UHPA family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_5014 | - | 5e-12 | 42.71% (96) | two component LuxR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0386 | - | 3e-12 | 23.68% (532) | LuxR/UHPA family transcriptional regulator |
| M. leprae Br4923 | MLBr_01753 | - | 4e-05 | 26.43% (227) | putative transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1522 | - | 3e-12 | 40.91% (88) | putative two-component system response regulator LuxR |
| M. marinum M | MMAR_0123 | - | 2e-11 | 29.24% (301) | LuxR family transcriptional regulator |
| M. avium 104 | MAV_4201 | - | 2e-15 | 30.30% (297) | transcriptional regulator, LuxR family protein |
| M. thermoresistible (build 8) | TH_3184 | - | 6e-11 | 50.82% (61) | PUTATIVE two component transcriptional regulator, LuxR family |
| M. ulcerans Agy99 | MUL_2876 | - | 9e-09 | 33.33% (114) | putative regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_3766 | - | 0.0 | 59.13% (526) | response regulator receiver protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0393|M.bovis_AF2122/97 ------------------------------MSKLLPRG-TVTLLLADVEG
Rv0386|M.tuberculosis_H37Rv ------------------------------MSKLLPRG-TVTLLLADVEG
MMAR_0123|M.marinum_M --MLASMSEIDPR-----AEAPLVDWSDVDMGELLPTG-TVTLLLADVEG
MLBr_01753|M.leprae_Br4923 MYSLGEMQKPVPVGADYLASCLVARLRSTDVPTDLHRGCTVTLFLGDVEG
MSMEG_4339|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_3766|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_5014|M.gilvum_PYR-GCK --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4201|M.avium_104 --------------------------------------------------
MUL_2876|M.ulcerans_Agy99 --------------------------------------------------
Mb0393|M.bovis_AF2122/97 STWLWETHPDDMGAAVARLDKAVSGVIAAHDGVRPVEQGEGDSFVLAFAC
Rv0386|M.tuberculosis_H37Rv STWLWETHPDDMGAAVARLDKAVSGVIAAHDGVRPVEQGEGDSFVLAFAC
MMAR_0123|M.marinum_M STRLWQNQPEPMTAAVAHLDSVLATTVATHHGVRPVEQGEGDSFVVAFAS
MLBr_01753|M.leprae_Br4923 LAELSETQPDEAADAIARLDCVVSEAVAAHGGVQQVVQGVRGNFLATFAR
MSMEG_4339|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_3766|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_5014|M.gilvum_PYR-GCK --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4201|M.avium_104 --------------------------------------------------
MUL_2876|M.ulcerans_Agy99 --------------------------------------------------
Mb0393|M.bovis_AF2122/97 ASDAVAAALDLQRARLAPIRLRIGVHTGEVALRDEG---NYAGPTINRTA
Rv0386|M.tuberculosis_H37Rv ASDAVAAALDLQRARLAPIRLRIGVHTGEVALRDEG---NYAGPTINRTA
MMAR_0123|M.marinum_M AREAIACALDLQRSPLGPIRLRIGVHTGDIQLRDPNDPTNYIGPTINRTA
MLBr_01753|M.leprae_Br4923 ASDATACALDLQLAPIVPVRFRIALHTGEVQISNDD--VNNVVFMMVQAA
MSMEG_4339|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_3766|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_5014|M.gilvum_PYR-GCK --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4201|M.avium_104 --------------------------------------------------
MUL_2876|M.ulcerans_Agy99 --------------------------------------------------
Mb0393|M.bovis_AF2122/97 RLRDLAHGGQTVLSGVTESLVIDRLPDKAWLVDLGTHALRDLSRPERVMQ
Rv0386|M.tuberculosis_H37Rv RLRDLAHGGQTVLSGVTESLVIDRLPDKAWLVDLGTHALRDLSRPERVMQ
MMAR_0123|M.marinum_M RIRELAHGGQTVISGATQLLVVDQLPDGAWLADLGLHPLRDLPRPERVMQ
MLBr_01753|M.leprae_Br4923 GLLDLACGGQTVLSSITGDLVVDGLPADTWLVDLGSHLLRDLARPVRVMQ
MSMEG_4339|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_3766|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_5014|M.gilvum_PYR-GCK --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4201|M.avium_104 --------------------------------------------------
MUL_2876|M.ulcerans_Agy99 --------------------------------------------------
Mb0393|M.bovis_AF2122/97 LCHPELRIDFPPLRVANDDVAHGLPVHLTRFVGRGAQITEVHRLVTDNRL
Rv0386|M.tuberculosis_H37Rv LCHPELRIDFPPLRVANDDVAHGLPVHLTRFVGRGAQITEVHRLVTDNRL
MMAR_0123|M.marinum_M LCHSGLQNDFPPLRTTKSIAVHRMPARLTRFVGRIAQMADVRSLLADNRL
MLBr_01753|M.leprae_Br4923 LCHRNLRRNLHELGIRTVPGGPSLPVPLTTFVGRAAQIKELQELLTEKRL
MSMEG_4339|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_3766|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_5014|M.gilvum_PYR-GCK --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4201|M.avium_104 --------------------------------------------------
MUL_2876|M.ulcerans_Agy99 --------------------------------------------------
Mb0393|M.bovis_AF2122/97 VTLTGAGGVGKTRLAAQLAAQIAGEFGR-AWFVDLAPITDPDLVPVTVAG
Rv0386|M.tuberculosis_H37Rv VTLTGAGGVGKTRLAAQLAAQIAGEFGR-AWFVDLAPITDPDLVPVTVAG
MMAR_0123|M.marinum_M VTLTGAGGAGKTRLAVEIAASAVDEFGDGLWYVDLAPVSHAEAVPVTVAR
MLBr_01753|M.leprae_Br4923 LTLVGPGGVGKTRLALQVVARVADEFSGELSYFDLAPDTDHDIFPITVL-
MSMEG_4339|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_3766|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_5014|M.gilvum_PYR-GCK --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4201|M.avium_104 --------------------------------------------------
MUL_2876|M.ulcerans_Agy99 --------------------------------------------------
Mb0393|M.bovis_AF2122/97 ALGLHDQPGRSTTDTVLRFLGGRPALVVLDNCEHLLDATAALVLALVKAC
Rv0386|M.tuberculosis_H37Rv ALGLHDQPGRSTTDTVLRFLGGRPALVVLDNCEHLLDATAALVLALVKAC
MMAR_0123|M.marinum_M ALGLSDQPGRSTVDALARFIGEHQVLVVLDNCEHLLDATAALLLELTGRC
MLBr_01753|M.leprae_Br4923 -------------DNLRRCIGDRRMLMVLDNCEYLLDVCANVMTTLLGAC
MSMEG_4339|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_3766|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_5014|M.gilvum_PYR-GCK --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4201|M.avium_104 --------------------------------------------------
MUL_2876|M.ulcerans_Agy99 --------------------------------------------------
Mb0393|M.bovis_AF2122/97 RGVRLLATCREPLRVEGEVSYRVPSLSLSDEAVEMFCYRAQRVRPDFRLT
Rv0386|M.tuberculosis_H37Rv RGVRLLATCREPLRVEGEVSYRVPSLSLSDEAVEMFCYRAQRVRPDFRLT
MMAR_0123|M.marinum_M PAVRLLATSREPLGVPGEVTFLVPSLSVT-EATELFTDRARRVRPDFAVT
MLBr_01753|M.leprae_Br4923 PSLTILATSREPIGVAGEVIWRVSMLSPADEAVELFTERAALVQPGFSVT
MSMEG_4339|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_3766|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_5014|M.gilvum_PYR-GCK --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4201|M.avium_104 --------------------------------------------------
MUL_2876|M.ulcerans_Agy99 --------------------------------------------------
Mb0393|M.bovis_AF2122/97 DDNSAAVTEICKRLDGLPLAIELAAARLRSMTLDEIIDGLRDRFALLTGG
Rv0386|M.tuberculosis_H37Rv DDNSAAVTEICKRLDGLPLAIELAAARLRSMTLDEIIDGLRDRFALLTGG
MMAR_0123|M.marinum_M DDNTTAVTEICNRLDCMPLAIELAAARVRALSIDEIRTGLHDRFRLLTGG
MLBr_01753|M.leprae_Br4923 DGNRQIVTEICQRLDGMPLAIELAAARIRTLSLTEIADGLDDRFRLLTGG
MSMEG_4339|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_3766|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_5014|M.gilvum_PYR-GCK --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4201|M.avium_104 --------------------------------------------------
MUL_2876|M.ulcerans_Agy99 --------------------------------------------------
Mb0393|M.bovis_AF2122/97 ARTAAHRQQTLWASVDWSYTLLTEPERTLFRRLAVFVGCFFVDDAQAVAC
Rv0386|M.tuberculosis_H37Rv ARTAAHRQQTLWASVDWSYTLLTEPERTLFRRLAVFVGCFFVDDAQAVAC
MMAR_0123|M.marinum_M ARTVVRRQQTLRASVDWSHALLTEPERVLFRRIAVFLGGFDLDAAQAVAG
MLBr_01753|M.leprae_Br4923 ARTAVRRQQTLRASMDWSYALLTESERALFRRLSAISGTFDLKVAYAVGH
MSMEG_4339|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_3766|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_5014|M.gilvum_PYR-GCK --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4201|M.avium_104 ------------------------------------------------MM
MUL_2876|M.ulcerans_Agy99 --------------------------------------------------
Mb0393|M.bovis_AF2122/97 SGDVQRYQVLDEITLLVDKSLVMADDNSGRTCYRLCETMRHYALEKLSEA
Rv0386|M.tuberculosis_H37Rv SGDVQRYQVLDEITLLVDKSLVMADDNSGRTCYRLCETMRHYALEKLSEA
MMAR_0123|M.marinum_M DSQVQRYQVVDELALLVDKSLVIAESGGGPTRYRLLETVRQYAQEKLAES
MLBr_01753|M.leprae_Br4923 DDLEEPDQVFDRLTMLIDKSLVIVEGRQGGSRYRLLETVRQYAMKKLEES
MSMEG_4339|M.smegmatis_MC2_155 ------------------------MTTATGSVGRASDHPALLEARAAHSR
Mvan_3766|M.vanbaalenii_PYR-1 ------------------------MLTDT-------QIDLLSAARTAHQR
Mflv_5014|M.gilvum_PYR-GCK --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4201|M.avium_104 LMAQAVLPTRAELLAALSVAIDLGLGQPAEHMLRAALIATRLCDRLGLSR
MUL_2876|M.ulcerans_Agy99 ---------------------------------------MGFSPRRAIPE
Mb0393|M.bovis_AF2122/97 GEVDAVFARHRDYYTALAARVDNPGPSDYSHCLDQAETEIDNLRAAFVWN
Rv0386|M.tuberculosis_H37Rv GEVDAVFARHRDYYTALAARVDNPGPSDYSHCLDQAETEIDNLRAAFVWN
MMAR_0123|M.marinum_M GEVEAVRSRHVTYYKSVAKLLDAPTGTDHERRLAQAEDELDNLRSAFGWS
MLBr_01753|M.leprae_Br4923 NEVDLVLARHRDHYMALGALLDTPGDIDHEQLVEQVETELDNLRSAFAWS
MSMEG_4339|M.smegmatis_MC2_155 AEWAAAYQAYLRAEAIGPMTLDDLDAYATTAWRLGHSREAVRLAERVYGQ
Mvan_3766|M.vanbaalenii_PYR-1 RDWAASYEAFELASRYAPLRTDDLEAFAFASWRLGHIKESSRAAERVFAE
Mflv_5014|M.gilvum_PYR-GCK --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4201|M.avium_104 QQRDCVYYTTLVMWVGCHADSHEYARWFGDDIAVRHDSYLVDWSGIPYLR
MUL_2876|M.ulcerans_Agy99 RTVGGVIDVVDMPDPPAFPTLADDEHPGWASRPIRESDATRHYREAFGDC
Mb0393|M.bovis_AF2122/97 RENSDTEGALALASSLLRVWMTRGRIQEGRAWFDSILADEN---------
Rv0386|M.tuberculosis_H37Rv RENSDTEGALALASSLLRVWMTRGRIQEGRAWFDSILADEN---------
MMAR_0123|M.marinum_M LETRDFDSALELATSLHPVWMTRGQGREGLAWLEAGLGNEAGLGNEAGLG
MLBr_01753|M.leprae_Br4923 RETGDIAGALQLASSLQPIWFGRGHMYEGLAWFDSIFEHKN---------
MSMEG_4339|M.smegmatis_MC2_155 LVRRDPATAATKAVDIALEWLTRGDLNIAQGWMNRARRLLT---------
Mvan_3766|M.vanbaalenii_PYR-1 LTRTDPNAAAMKANELALAWLVRGDINIGQGWMSRARRLLA---------
Mflv_5014|M.gilvum_PYR-GCK --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4201|M.avium_104 FLASNVGRGQPLAHRLSVMATLFANARGHISRLIHSHCASA---------
MUL_2876|M.ulcerans_Agy99 NVDPTDDPMAVVAEAIDVNAAAVRHALESQGDVHAVN-------------
Mb0393|M.bovis_AF2122/97 ARHLEVAAAVRARALADKALLDIFVDAAAG-----MEQAQQALVIAREVD
Rv0386|M.tuberculosis_H37Rv ARHLEVAAAVRARALADKALLDIFVDAAAG-----MEQAQQALVIAREVD
MMAR_0123|M.marinum_M NEDVQVSPSTLARALADKVTLLAWTGSMAG-----FDDAERALTIARELA
MLBr_01753|M.leprae_Br4923 IEHLVAPKEVLARAVANKVMLHAILASSPPDGSDLVTQAQQALTMAREIG
MSMEG_4339|M.smegmatis_MC2_155 -------GAPTGPTHCYLAYLDVVLAVAEQDPEELARRAEAVRHLCDSVE
Mvan_3766|M.vanbaalenii_PYR-1 -------AAEESQAHGYLIYLDAVVAAISQDLDALAGHVRSLRETSERLD
Mflv_5014|M.gilvum_PYR-GCK --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4201|M.avium_104 ----ALLADRIGLGPNVQAALAYTFERYDGGGLPTGARGEDIPIQMRIAQ
MUL_2876|M.ulcerans_Agy99 ---------ALETLLDLSSLEREMIEDGAARRTLALLQVQEALSKLRAVD
Mb0393|M.bovis_AF2122/97 EPALLSRALTACGLIAVAVARADAAASYFAEAIDLARAVDDRWRLAQILT
Rv0386|M.tuberculosis_H37Rv EPALLSRALTACGLIAVAVARADAAASYFAEAIDLARAVDDRWRLAQILT
MMAR_0123|M.marinum_M DPALLIRALVARGVITAYDA--DVARPYFDEAAQLARELGDSWRLSQILS
MLBr_01753|M.leprae_Br4923 DSAVLARALTACGFSSGYDT--EVARPYFAEAVELARTQGDKWTLSQIRL
MSMEG_4339|M.smegmatis_MC2_155 DPALESLSLVSQAIAALHQGRVADGYALVDEALLPLLAG-----------
Mvan_3766|M.vanbaalenii_PYR-1 VPAVTALGLIAAGIEAILHARTAEGYALIDEAILPLMAD-----------
Mflv_5014|M.gilvum_PYR-GCK --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4201|M.avium_104 LADMVEVHHRSYGVAGAVAMVGARRGGQFDPGIADVFLR-----------
MUL_2876|M.ulcerans_Agy99 DVAMIVDRAPR---------------------------------------
Mb0393|M.bovis_AF2122/97 FQAVDAVVAGDPVAARPAAQEARELAAAIGDHSNALWCRWCLGYAQLMRG
Rv0386|M.tuberculosis_H37Rv FQAVDAVVAGDPVAARPAAQEARELAAAIGDHSNALWCRWCLGYAQLMRG
MMAR_0123|M.marinum_M LQTRAAMAAGDPIALEAAGEEGLRIAEAIGDRTTSRECRGALGWVRAWRG
MLBr_01753|M.leprae_Br4923 WGVVGFCVSGDPVALRAAAEAADDLAQEIGDRFVSLQCRLLLSIAQLWQG
MSMEG_4339|M.smegmatis_MC2_155 ------------------------------------------HVRVEWAG
Mvan_3766|M.vanbaalenii_PYR-1 ------------------------------------------QVPIEWAG
Mflv_5014|M.gilvum_PYR-GCK --------------------------------------------------
TH_3184|M.thermoresistible__bu --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4201|M.avium_104 --------------------------------------DADAILAGPQTG
MUL_2876|M.ulcerans_Agy99 --------------------------------------------------
Mb0393|M.bovis_AF2122/97 ELAAAAAQFGEVVDEAEASQEVLHKANSLQGLAFALAYQGELSAARAAAD
Rv0386|M.tuberculosis_H37Rv ELAAAAAQFGEVVDEAEASQEVLHKANSLQGLAFALAYQGELSAARAAAD
MMAR_0123|M.marinum_M DPIGALHQLGEAIAEASAAHDLLLLMISQVVQGFTYAYVGDADGACACAD
MLBr_01753|M.leprae_Br4923 DMDGAIVRSGEVVAGAEAAHDTVTRTFGLYVQTRALVHR-DVSAALVTAG
MSMEG_4339|M.smegmatis_MC2_155 DIYCVVLNLCHKLADHPRMRAWTQSMERWCDVHSASPFYRVCDVHRLQLA
Mvan_3766|M.vanbaalenii_PYR-1 DIYCMVLHHCHKLADLPRMRSWTQSMEQWCGLSGSVPYGGVCDVHRLQVQ
Mflv_5014|M.gilvum_PYR-GCK --------------------------------------MSSEPVRIVLVD
TH_3184|M.thermoresistible__bu ----------------------------------MEPVAAPSPVRIVLVD
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------MTDTEVGVLLVD
MAV_4201|M.avium_104 DAWAAALREAPDRHRVDEQSLDAALVALGDFVDLKCPFTLGHSRAVARLA
MUL_2876|M.ulcerans_Agy99 ----------ELVESCGFDRAVLFRVHEGRLVMESAYFGEDREGAEKMVA
Mb0393|M.bovis_AF2122/97 AALEA-AELGEYFAGMGYSALTTAALAAGDVQTAQHASEAAWRNLS----
Rv0386|M.tuberculosis_H37Rv AALEA-AELGEYFAGMGYSALTTAALAAGDVQTAQHASEAAWRNLS----
MMAR_0123|M.marinum_M AVFTSSAELVGANEGLGYATAAIACQAAGDATAAWKAYQKARELVG----
MLBr_01753|M.leprae_Br4923 LVVEAAAELSGVYQGIGYAAMVFAALAMGDVAAAVEASEACRPHLG----
MSMEG_4339|M.smegmatis_MC2_155 AADDDYRRLEDQLFSASTALEDVNSWVGAEGFYQLGEVRRLRGDTEGALA
Mvan_3766|M.vanbaalenii_PYR-1 VASTDLRGLEDRLGTASRALVEVNAWAAAEGYYQLGEVRRLKGDLDGAAT
Mflv_5014|M.gilvum_PYR-GCK DHEMVIEGLKAMLAAFADRVCVVGQSVGAD--------------------
TH_3184|M.thermoresistible__bu DHEMVIEGLKAMLAAFEDRVCVVGHAVGAE--------------------
MAB_1522|M.abscessus_ATCC_1997 DQELVRTGLRRILRR-KDGFAIVGECADGS--------------------
MAV_4201|M.avium_104 GQAARAAGLDADAVALTRRAGHVHDLGRIG--------------------
MUL_2876|M.ulcerans_Agy99 FAQSVAPLLDHMLIETQMIRRHAPAIVRDAR-------------------
*
Mb0393|M.bovis_AF2122/97 LALPLSAAVQRAFNAQAALAGGDLSAARRWCDDAVQSMTGHHLAMALA-T
Rv0386|M.tuberculosis_H37Rv LALPLSAAVQRAFNAQAALAGGDLSAARRWCDDAVQSMTGHHLAMALA-T
MMAR_0123|M.marinum_M MDPQMAGVFP--FGALAPLVSGDLSAARRWADDVVSTSYGCYLSVALT-A
MLBr_01753|M.leprae_Br4923 ADHGLVAIHL-ELMAAVALARGDVIVARRLADNSVSATTGWHQMAALT-T
MSMEG_4339|M.smegmatis_MC2_155 AFAKARSLGKDPQPGEALLHCSVGQSRKAWTDLRVALAGAGPLDRMRL-L
Mvan_3766|M.vanbaalenii_PYR-1 AFEQARALGLDPQPGEALLACRRGDNAAAWTSIRLALAGGDRLARVRL-L
Mflv_5014|M.gilvum_PYR-GCK ---------------QVMGVVTDLDPDIVLCDVRMQGSSGLDVCQQLR-R
TH_3184|M.thermoresistible__bu ---------------RAVEVVAELDPDIVLCDVRMQNTSGLDLCLTLR-E
MAB_1522|M.abscessus_ATCC_1997 ---------------EVAAAVSRARPDVVIMDLRMKQMSGIEAIRLLH-A
MAV_4201|M.avium_104 -------------VSNQIWSRPGPLSGSQFERVRLHPYLTVRILDQVPGL
MUL_2876|M.ulcerans_Agy99 --------------NDPRVNRPIVDFSLTHSYVAAPVMPTGKMIGFLH--
Mb0393|M.bovis_AF2122/97 RARIAVAEGKREEAERDAHKALACAAESGAHLDLPDVLECLAGLASDAGT
Rv0386|M.tuberculosis_H37Rv RARIAVAEGKREEAERDAHKALACAAESGAHLDLPDVLECLAGLASDAGT
MMAR_0123|M.marinum_M RARVALAQGELGQADRDSHAALSCSAANGTTLGVADTLECLAELAATEGD
MLBr_01753|M.leprae_Br4923 RARIAMAQGEPELARADIHAALACGADIQASLGISDSMELLAELISQGDN
MSMEG_4339|M.smegmatis_MC2_155 RAAVVVALARDDIGEAQRYCDQLAAGAEAFATPGYRGWAAHARGAVLVRR
Mvan_3766|M.vanbaalenii_PYR-1 RAAVEIALGRDALSEAENYCRELEADAKAFGTPGFRAWAAHARGAVAVRR
Mflv_5014|M.gilvum_PYR-GCK RDPDRKIVMLSVYDDEQYLFQAMRVGASGYLLKSI-SSEDLVEQLESVHS
TH_3184|M.thermoresistible__bu QAPHRKVVMLSVYDDEQYLYQALRVGASGYLLKSI-SSDELVRQLEMVHR
MAB_1522|M.abscessus_ATCC_1997 AQ-GPPALALTTFDDDELLSGALRAGAAGFILKDS-PAEELVRAVHAVAR
MAV_4201|M.avium_104 RRLAEVAGNHHECLDGSGYPRGLAGSALGMPDRILAAAVCYQSGREPRPY
MUL_2876|M.ulcerans_Agy99 ---ADRLYSGRIVDEIDRDTVWAFAEGFGYAYERTVLLERMRRQHAEVRS
.
Mb0393|M.bovis_AF2122/97 HHAAARLFGAAEAIRQQIGSVRFAIYRSDYVQSVTALRDAMGEKDFAAAW
Rv0386|M.tuberculosis_H37Rv HHAAARLFGAAEAIRQQIGSVRFAIYRSDYVQSVTALRDAMGEKDFDAAW
MMAR_0123|M.marinum_M RREAARLLASAEAIRHRTGEVRLKILDAHCEVVLAELRNELGEQDFAAVW
MLBr_01753|M.leprae_Br4923 HRQAGRLFGAASAQREKTGEVRFKVWDAGYESAVAVLRGAMGCKDFDSAW
MSMEG_4339|M.smegmatis_MC2_155 GEFEAALDNLGAALREYR--LQQERYDIAEVYEWMALAHRGLGDDTAADT
Mvan_3766|M.vanbaalenii_PYR-1 GDFGVALESLQSALREYR--VQQSRYETAEVYEWMALAKRGLGDREGAVA
Mflv_5014|M.gilvum_PYR-GCK G---------------------------------------------KTAI
TH_3184|M.thermoresistible__bu G---------------------------------------------QTAL
MAB_1522|M.abscessus_ATCC_1997 G---------------------------------------------EAYL
MAV_4201|M.avium_104 R---------------------------------EQLSEAEAARRLRGRV
MUL_2876|M.ulcerans_Agy99 ALAS-------------------------------------ADEAARALQ
Mb0393|M.bovis_AF2122/97 AEGAALSIKETIAYAQRGHSWRKRPATGWESLTPTEIDVVRLVGEGLANK
Rv0386|M.tuberculosis_H37Rv AEGAALSIKETIAYAQRGHSWRKRPATGWESLTPTEIDVVRLVGEGLANK
MMAR_0123|M.marinum_M GQGAVISTDEVISYVRRGRGTRRRPSSGWGSLTPTEHDVVRLVQEGLSNK
MLBr_01753|M.leprae_Br4923 AEGAAMPIDDAITYAQRGRGNRKRPTTGWESLTPAEHNVIRLVSEGLDTK
MSMEG_4339|M.smegmatis_MC2_155 DIATAENIYEQLAVQPSGVCGRASP----GGLTRREIEVLRAIAGGATNR
Mvan_3766|M.vanbaalenii_PYR-1 DAATADAIYVQLGVEPAGICGAPTP----GGLTRRELDVLTRIARGATNR
Mflv_5014|M.gilvum_PYR-GCK DPTMAARAVE----------WPGAR----QGLTQRESEILALVVNGLSNR
TH_3184|M.thermoresistible__bu DPGMAARAVDTAARLQRDEFWPGAR----HGLTQRESEILSYVVNGLSNR
MAB_1522|M.abscessus_ATCC_1997 DPAVTSRVLN-AYRRAPAAVSGDAQ----DKLTARELDVLALIASGATNS
MAV_4201|M.avium_104 RCGELDPVAAEAVLHAAGQPVGPRPNPRPDGLTPREIEVLGHVARGASNK
MUL_2876|M.ulcerans_Agy99 DADLDLRKIEPVERSPAARSLAEVQTRVMAMLTRREVEVLRLMAAGRTNQ
** * ::: : * .
Mb0393|M.bovis_AF2122/97 DIATRLFVSPRTVQTHLTHVYTKLGFTSRLQLAQAAARRT---------
Rv0386|M.tuberculosis_H37Rv DIATRLFVSPRTVQTHLTHVYTKLGFTSRLQLAQAAARRT---------
MMAR_0123|M.marinum_M DIAARMFISPRTVQTHLTHVYTKLGLTSRIQLVHEVARHA---------
MLBr_01753|M.leprae_Br4923 DIAARLFVSVRTVHTHLTRIYSKLGLTSRVQLVQEAARHN---------
MSMEG_4339|M.smegmatis_MC2_155 QVAHQFVISDKTVGRHLANIYTKLGVSSRTAAVTWAYQNGVVRKDN---
Mvan_3766|M.vanbaalenii_PYR-1 QVAEQLHLSDKTVSRHLANIYAKLGVSTRTAAANWAFQQGVLTDER---
Mflv_5014|M.gilvum_PYR-GCK AIAAKLIIGDETVKTHLSSIYRKLGVSDRTAAVATALREGIFQ------
TH_3184|M.thermoresistible__bu GIAAKLVIGDETVKSHLRSIYRKLGVSDRAAAVATALREGIYQ------
MAB_1522|M.abscessus_ATCC_1997 EIAEQLVISEVTVKSHIGRIFVKLDLRDRAAAIVYAYDHGIVTPK----
MAV_4201|M.avium_104 EIAAALVISEKTARNHVERTYAKIGVSNRIGASMYALQHGLVPAAPPHS
MUL_2876|M.ulcerans_Agy99 QIADELVISAGTVKSHVKRVLRKLHATNRAEAASAYVRLASVSEVG---
:* : :. *. *: *: *