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SAPTAAPRDRVRHPRRPADSVLVRREAILDAAWAVASAQGFDGVQMRAVAAQAGIAASSLYRHFRSKSHL LVTVLAREFERLDTEFDCTTGELAPQARLGRLTTHLHMAWQANPHLTEAMVRAFVVADSEAAGAIEHAVA VIEDMLARALGGPTPSAHDRDVASLIADVWLANLIAVIGGRIDADLARERIDRTTRQLVHGTDTTT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3803 | - | - | 100% (207) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_0584 | - | 4e-34 | 44.51% (182) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_2958 | - | 3e-08 | 28.85% (156) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3605 | - | 6e-35 | 42.86% (182) | transcriptional regulatory protein TetR-family |
| M. gilvum PYR-GCK | Mflv_4581 | - | 3e-46 | 53.98% (176) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3574 | - | 6e-35 | 42.86% (182) | transcriptional regulatory protein TetR-family |
| M. leprae Br4923 | MLBr_02568 | - | 2e-05 | 38.98% (59) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0579c | - | 2e-33 | 44.13% (179) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4839 | - | 2e-44 | 54.12% (170) | TetR family transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_6042 | - | 2e-36 | 45.30% (181) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_1745 | - | 4e-37 | 46.07% (178) | TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY) |
| M. ulcerans Agy99 | MUL_4145 | - | 2e-34 | 43.48% (184) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0321 | - | 7e-46 | 53.98% (176) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_3803|M.avium_104 -------------------------------------------MSAPTAA
MMAR_4839|M.marinum_M -------------------------------------------MAEVEAA
MSMEG_6042|M.smegmatis_MC2_155 ------------------------------------------MTNVAVLS
TH_1745|M.thermoresistible__bu MSSSTGTNPGRGSDSTGSETNGAAATGAGSGSTGTSRTRGRQVTNVAVLT
Mb3605|M.bovis_AF2122/97 ---------------------------------------------MAVLA
Rv3574|M.tuberculosis_H37Rv ---------------------------------------------MAVLA
MUL_4145|M.ulcerans_Agy99 ---------------------------------------------MAVLA
MAB_0579c|M.abscessus_ATCC_199 -------------MATPRTSSASEAAQSGDGDTDATS----QPAAVSALS
Mflv_4581|M.gilvum_PYR-GCK -------------MTFPQARSHGKTLPSEANS-----------VATEKRA
Mvan_0321|M.vanbaalenii_PYR-1 -------------MTFPQARSRGTTLPSEANS-----------VATEKRA
MLBr_02568|M.leprae_Br4923 ------------------------------------------------MA
:
MAV_3803|M.avium_104 PRDRVRHPRRPADSVLVRREAILDAAWAVASAQGFDGVQMRAVAAQAGIA
MMAR_4839|M.marinum_M MS-------RPGAHTASS-AAVLDATRAVATLGGFKAVHFKSVAKQAGVT
MSMEG_6042|M.smegmatis_MC2_155 ESE------LGSEAQRERRKRILDATLAIASKGGYEAVQMRAVAERADVA
TH_1745|M.thermoresistible__bu DSE------LGSEAQRERRKRILDATLAIASKGGYEAVQMRAVAERADVA
Mb3605|M.bovis_AF2122/97 ESE------LGSEAQRERRKRILDATMAIASKGGYEAVQMRAVADRADVA
Rv3574|M.tuberculosis_H37Rv ESE------LGSEAQRERRKRILDATMAIASKGGYEAVQMRAVADRADVA
MUL_4145|M.ulcerans_Agy99 ESE------LGSEAQRERRKRILDATMAIASKGGYEAVQMRAVADRADVA
MAB_0579c|M.abscessus_ATCC_199 DDD------LGSSAQRERRKRILDATLAIASKGGYEAVQMRTVAERADVA
Mflv_4581|M.gilvum_PYR-GCK ANA------SRSRASARRRETILDAALTVAAAGGYEAVQMRTVAERVGIA
Mvan_0321|M.vanbaalenii_PYR-1 ANA------SRSRASARRRETILDAALAVAAAGGYEAVQMRTVAERVGIA
MLBr_02568|M.leprae_Br4923 GG-------AKRIPRAVREQQMLDAAVQMFSVNGYHKTSMDAIAAEAQIS
:***: : : *:. . : ::* .. ::
MAV_3803|M.avium_104 ASSLYRHFRSKSHLLVTVLAREFERLDTEFDCTTGEL-APQARLGRLTTH
MMAR_4839|M.marinum_M VGSVYDHFTSKTHLLVTLLAREFVRLDEERDWSTCAA-SPIRRVESLTRR
MSMEG_6042|M.smegmatis_MC2_155 VGTLYRYFPSKVHLLVSALGREFERIDAKTDRAALAGGTPYQRLNFMVGK
TH_1745|M.thermoresistible__bu VGTLYRYFPSKVHLLVSALGREFERIDAKTDRSTLVGDTPYERLNFMVSR
Mb3605|M.bovis_AF2122/97 VGTLYRYFPSKVHLLVSALGREFSRIDAKTDRSAVAGATPFQRLNFMVGK
Rv3574|M.tuberculosis_H37Rv VGTLYRYFPSKVHLLVSALGREFSRIDAKTDRSAVAGATPFQRLNFMVGK
MUL_4145|M.ulcerans_Agy99 VGTLYRYFPSKVHLLVSALGREFSRIDAKTDRSAMTGGTPFQRLNFMVGK
MAB_0579c|M.abscessus_ATCC_199 VGTLYRYFPSKVHLLVSALEREFEQIDAKSDRNAVSGGTPYERLHAAITR
Mflv_4581|M.gilvum_PYR-GCK VGTLYRYFPAKTHLLVAALTREFRRLDSAGDWASGEG-PPLERLERLTAH
Mvan_0321|M.vanbaalenii_PYR-1 VGTLYRYFPAKTHLLVAALTREFRRLDSAGDWAGGEG-TPLERLERLTAH
MLBr_02568|M.leprae_Br4923 KPMLYLYYGSKEDLFGACLNREMSRFIAMVRADIDFTQSPKDLLRNTIVS
:* :: :* .*: : * **: :: .* :
MAV_3803|M.avium_104 LHMAWQANPHLTEAMVRAFVVADSEAAGAIEHAVAVIEDMLARALG-GPT
MMAR_4839|M.marinum_M LHDEWQQNVKLTEAVVRAFVTAGTDEALAAQHAADLIESMLARALS-GGT
MSMEG_6042|M.smegmatis_MC2_155 LNRAMQRNPLLTEAMTRAFVFADASAAGEVDHVGKLMDSMFARAMS-DGE
TH_1745|M.thermoresistible__bu LNRAMQRNPLLTEAMTRAFVFADASAAGEVDHVGRLMDSMFARAMA-DGE
Mb3605|M.bovis_AF2122/97 LNRAMQRNPLLTEAMTRAYVFADASAASEVDQVEKLIDSMFARAMA-NGE
Rv3574|M.tuberculosis_H37Rv LNRAMQRNPLLTEAMTRAYVFADASAASEVDQVEKLIDSMFARAMA-NGE
MUL_4145|M.ulcerans_Agy99 LNRAMQRNPLLTEAMTRAYVFADASAATEVDQVEKLIDSMFARAMA-DGE
MAB_0579c|M.abscessus_ATCC_199 LNRNMQRNPLLTEAMTRALVFADASAAGEVDHVGRLMDGIFARAMAGEDD
Mflv_4581|M.gilvum_PYR-GCK LHDRWQRDPRLTTAMTRAFAVADTRAAAELDRAADEIQILLARTLR-GGE
Mvan_0321|M.vanbaalenii_PYR-1 LHDRWQRDPWLTTAMTRAFAVADTRAAAELDRAADEIQILLARTLR-GGE
MLBr_02568|M.leprae_Br4923 FLRYIDAN-RASWIVMYIQAMSLPAFAQTVREARDQITELVAGLMR-VGT
: : : : : . : . * .. : :.* :
MAV_3803|M.avium_104 PSAHDRDVASLIADVWLANLIAVIGGRIDADLARERIDRTT--------R
MMAR_4839|M.marinum_M EGIHERQIAGLIADIWLANLMAFVGGRATAEQTRECIDGAMRLVLDVGGR
MSMEG_6042|M.smegmatis_MC2_155 PTEDQYHIARVISDVWLSNLLAWLTRRASATDVSKRLDLAV--------R
TH_1745|M.thermoresistible__bu PTEDQYHIARVISDVWLSNLLAWLTRRASATDVSKRLELAV--------R
Mb3605|M.bovis_AF2122/97 PTEDQYHIARVISDVWLSNLLAWLTRRASATDVSKRLDLAV--------R
Rv3574|M.tuberculosis_H37Rv PTEDQYHIARVISDVWLSNLLAWLTRRASATDVSKRLDLAV--------R
MUL_4145|M.ulcerans_Agy99 PTEDQYHIARVISDVWLSNLLAWLTRRASATDVSKRLDLAV--------R
MAB_0579c|M.abscessus_ATCC_199 PTDAQFHIARVISDVWTSNMIAWLTRRASATDVSHRLDRTV--------R
Mflv_4581|M.gilvum_PYR-GCK PTPTDLHVAGVISDIWLANLVAFSGHRATAADTRERIDRAT--------R
Mvan_0321|M.vanbaalenii_PYR-1 PTPADLHVAGVISDIWLANLVAFSGDRATAADTRDRIDRAT--------R
MLBr_02568|M.leprae_Br4923 RSSRPDHEYEIMAGALVGAGEAMATRLTTGDIAVDEAAELMINLFWHGLK
. :::. . * . . . :
MAV_3803|M.avium_104 QLVHGTDTTT-----
MMAR_4839|M.marinum_M QRSLAIPTVSLRY--
MSMEG_6042|M.smegmatis_MC2_155 LLIGTEEQPKI----
TH_1745|M.thermoresistible__bu LLVGDGKNPKV----
Mb3605|M.bovis_AF2122/97 LLIGDQDSA------
Rv3574|M.tuberculosis_H37Rv LLIGDQDSA------
MUL_4145|M.ulcerans_Agy99 LLIGDQEATA-----
MAB_0579c|M.abscessus_ATCC_199 LLLGIT---------
Mflv_4581|M.gilvum_PYR-GCK RVVTSAARPTANR--
Mvan_0321|M.vanbaalenii_PYR-1 RVVTNAARPTANR--
MLBr_02568|M.leprae_Br4923 GAPADRDFGPSIVAG