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VDTHRLKYFLRIAEQGSITGAAASLGIAQPALSRQIRLLEEDLGVALFRRTRRGVQLTEEGERLRASTAA PLRQLELAMQYAGSPIARLARGVRLGILDTTVDVFAAHLLSSLAAAFPKVTFSVETGSTDQLVEAMLKGA VDVAVINPVPDDRIFYRDLLTEDLVVVGAATSGLDSGQMMPFTELVELPLVVPRSHTGIGNVIENAALRR KVKISWRIATDSLALTKRLVAAGLVYGVLPLSACLNEIDSNQLRYTPLTEPPLTHRVGVAATSNLELPRE VTAKVGNILREETAHLIKTGRWPARLLSPQPWDPAVT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3102 | - | - | 100% (317) | LysR substrate binding domain-containing protein |
| M. avium 104 | MAV_1538 | - | 3e-20 | 26.26% (278) | transcriptional regulator, LysR family protein |
| M. avium 104 | MAV_2838 | - | 7e-20 | 26.35% (296) | hydrogen peroxide-inducible genes activator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2303c | - | 3e-12 | 30.00% (210) | LysR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1833 | - | 1e-110 | 63.38% (314) | LysR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv2282c | - | 3e-12 | 30.00% (210) | LysR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02041 | oxyR | 1e-21 | 27.70% (296) | putative LysR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2707 | - | 5e-20 | 29.50% (278) | putative transcriptional regulator |
| M. marinum M | MMAR_4157 | - | 3e-19 | 27.46% (244) | LuxR family transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_0708 | - | 1e-33 | 32.13% (305) | transcriptional regulator, LysR family protein |
| M. thermoresistible (build 8) | TH_3504 | - | 5e-13 | 29.87% (154) | PUTATIVE putative transcriptional regulator |
| M. ulcerans Agy99 | MUL_4020 | - | 4e-19 | 27.46% (244) | LuxR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_3362 | - | 6e-18 | 29.06% (265) | LysR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_3102|M.avium_104 -------MDTHRLKYFLRIAEQGSITGAAASLGIAQPALSRQIRLLEEDL
Mflv_1833|M.gilvum_PYR-GCK -------MDTHRLKYFLRIAEEGSITRAASLLGMAQPALSRQLQLLEEDL
MMAR_4157|M.marinum_M -------MELYQLRYFQAVAECGTLRGASEQLLVSQSAVSRAITLLEAEI
MUL_4020|M.ulcerans_Agy99 -------MELYQLRYFQAVAECGTLRGASEQLLVSQSAVSRAITLLEAEI
Mb2303c|M.bovis_AF2122/97 MPLSSRMPGLTCFEIFLAIAEAGSLGGAARELGLTQQAVSRRLASMEAQI
Rv2282c|M.tuberculosis_H37Rv MPLSSRMPGLTCFEIFLAIAEAGSLGGAARELGLTQQAVSRRLASMEAQI
MAB_2707|M.abscessus_ATCC_1997 -------MAEGDYEWYITLAELQNVTAAADQLRLAQPTLTRMLARLERRL
Mvan_3362|M.vanbaalenii_PYR-1 -------MELRQLEYLVAVVEERSFTKAAQRERVAQPAVSAQIRRLERQV
MSMEG_0708|M.smegmatis_MC2_155 -------MDLKGLNALLVVADAGSVTKAARILHVEQPAVSRQIKLLETEL
MLBr_02041|M.leprae_Br4923 MSDKSYQPTIAGLRAFVAVVEKGHFSAAASFLGVRQSTLSQALAALESGL
TH_3504|M.thermoresistible__bu --VPSPKIDLRRLAQFVAVAELGSFTRAAATLHLSQQALSSAVRALENDV
:.: . *: : * ::: : :* :
MAV_3102|M.avium_104 GVALFRRTRRGVQLTEEGERLRASTAAPLRQLELAMQYAGSPIARLARGV
Mflv_1833|M.gilvum_PYR-GCK GVALFRRNRRGVELTDAGERLRSSTAAPLRQLELAVQYAAFPLARLKRAM
MMAR_4157|M.marinum_M GVQLFTRRGRTNELNRYGQALLVGSRLAQRSVSSAIDNVRELAGVSGGTV
MUL_4020|M.ulcerans_Agy99 GVQLFTRRGRTNELNRYGQALLVGSRLAQRSVSSAIDNVRELAGVSGGTV
Mb2303c|M.bovis_AF2122/97 GVRLAIRTTRGSQLTPAGIVVAEWAARLLEVADEIDAGLGSLRTEGRQRI
Rv2282c|M.tuberculosis_H37Rv GVRLAIRTTRGSQLTPAGIVVAEWAARLLEVADEIDAGLGSLRTEGRQRI
MAB_2707|M.abscessus_ATCC_1997 GVQLFDRHGKRLALNPFGRIFYQHARRAQLELDSARRAIDDLANPAEGEI
Mvan_3362|M.vanbaalenii_PYR-1 GQPLLTRSHRGVRVTPAGAALLPHARAALAAVRDAQAAVDDVANLVRGAV
MSMEG_0708|M.smegmatis_MC2_155 GVALFERSRRGMVLTDAGRILVERARRVVDELEKAEAELRAEVSGVRGIV
MLBr_02041|M.leprae_Br4923 GVQLIERSTRRVFVTTQGRHLLPRAQAAIEAMDAFTAAAAGESDPLRGGM
TH_3504|M.thermoresistible__bu GADLFTRDGRRISLTTAGRTLLAEGKPLLAAARTVAEHVRQTEAAAQAHY
* * * : :. * .
MAV_3102|M.avium_104 RLGILDTTVDVFAAHLLSSLAAAFPK-----VTFSVETGSTDQLVEAMLK
Mflv_1833|M.gilvum_PYR-GCK LIGIPESAIDVLAAPLMTRLGSAFPD-----AQFAVTVGSTDHLVEAMLK
MMAR_4157|M.marinum_M ALGFLHSLGMQTVPHLIRLHHSRFPQ-----ARFELHQRSGQGVLSDLVS
MUL_4020|M.ulcerans_Agy99 ALGFLHSLGMQTVPHLIRLHHSRFPQ-----ARFELHQRSGQGVLSDLVS
Mb2303c|M.bovis_AF2122/97 RVVASQTIAEQLMPHWMLSLRAADMRRGGTVPEVILTATNSEHAIAAVRD
Rv2282c|M.tuberculosis_H37Rv RVVASQTIAEQLMPHWMLSLRAADMRRGGTVPEVILTATNSEHAIAAVRD
MAB_2707|M.abscessus_ATCC_1997 RLGFLHTFGPTLIAGLIAGFATTSPH-----VRFVLEQGAAGSLDDLVAT
Mvan_3362|M.vanbaalenii_PYR-1 AIG-TVTLHPVDVARLMADFHAEHPG-----VEITLGTDTSDVLLAKLED
MSMEG_0708|M.smegmatis_MC2_155 SVGILDSVTDLVAEELVSDVRRRYPN-----VRLRVFTAFAGQLRSWLYD
MLBr_02041|M.leprae_Br4923 RLGLIPTVAPYVLPTMLTGLTHRLPT-----LTLRVVEDQTEHLLTALRE
TH_3504|M.thermoresistible__bu VIGHTPALSGAEAYALIEPAVTAYPS-----TSFTLRQLYPDALTDAVFD
: : : . : :
MAV_3102|M.avium_104 GAVDVAVIN-PVPDD---RIFYRDLLTEDLVVVGAATSGLDSG-QMMPFT
Mflv_1833|M.gilvum_PYR-GCK GSVDIALIN-PVPDD---RVFYREILTEEFVLVGGPDSPLEPE-KPLQFA
MMAR_4157|M.marinum_M GVTDVSLSF-PAAFEGYGEIAWQTLFTQQLYAVVSTDHPLAGR-RLIRFP
MUL_4020|M.ulcerans_Agy99 GVTDVSLSF-PAAFEGYGEIAWQTLFTQQLYAVVSTDHPLAGR-RLIRFP
Mb2303c|M.bovis_AF2122/97 GIADLGFIENPCPPTG---LGSVVVARDELVVVVPPGHKWARRSRVVSAR
Rv2282c|M.tuberculosis_H37Rv GIADLGFIENPCPPTG---LGSVVVARDELVVVVPPGHKWARRSRVVSAR
MAB_2707|M.abscessus_ATCC_1997 GDLDVAIVS-PRPRRAN--LGWRNLFRQRLGVAVPTDHRLAQA-QDVSMV
Mvan_3362|M.vanbaalenii_PYR-1 GRLDAAIVS-IGADEDPAGLEYEVITDEALEAAVTAQHRLARR-KSLSLK
MSMEG_0708|M.smegmatis_MC2_155 GELDVALLFGVTDQTA---LKTLPVASEKLWAVAPKEAALQPD-IPVGFD
MLBr_02041|M.leprae_Br4923 GALDAAMIALPVETAG---IAEIPIYDEDFVLALPPGHPLSGK-RRVPTT
TH_3504|M.thermoresistible__bu GTVQLGLRRGVVPTPE---LATAVIGYHRVRVAFVDSHPLAAR-ESVDIT
* : .. : : . . . :
MAV_3102|M.avium_104 ELVELPLVVPRSH--TGIGNVIENAALRRK----VKISWRIA-TDSLALT
Mflv_1833|M.gilvum_PYR-GCK DLVELPLVVPRST--TGLGQALYNAALRAK----VTIDYRIT-TDSTRVM
MMAR_4157|M.marinum_M ELAAYPFVVLDRD--HTLRRIVDAACARHG----IDPTLAFE-GTDVGTL
MUL_4020|M.ulcerans_Agy99 ELAAYPFVVLDRD--HTLRRIVDAACARHG----IDPTPAFE-GTDVGTL
Mb2303c|M.bovis_AF2122/97 ELAQTPLVTREPN--SGIRDSLTAALRDTLGEDMQQAPPVLE-LSSAAAV
Rv2282c|M.tuberculosis_H37Rv ELAQTPLVTREPN--SGIRDSLTAALRDTLGEDMQQAPPVLE-LSSAAAV
MAB_2707|M.abscessus_ATCC_1997 DLADEPFVAMHPG--FGMRRLLEELCAAAQ----FQPRIVLE-SSNLMTV
Mvan_3362|M.vanbaalenii_PYR-1 QLCEYPVISLPAG--TGLRSRLDDACAAAG----LRPRIAFE-ATSPLEL
MSMEG_0708|M.smegmatis_MC2_155 EIARHPLIVPVRG--NALRSLVDEAAARAG----VDIDISVE-TNASRVQ
MLBr_02041|M.leprae_Br4923 ALAQLPLLLLDEG--HCLRDQTLDICRKSG----VQAELANTRAASLATA
TH_3504|M.thermoresistible__bu ELAREQVALWAPPGTSYYSDFLMGACRRAG----FEPDYVVSRVQGAATV
: .
MAV_3102|M.avium_104 KRLVAAGLVYGVLPLSACLNEIDSNQLRYTPLTEPPLTHRVGVAATSNLE
Mflv_1833|M.gilvum_PYR-GCK VCLIESGLAYGVLPLSACGREFAESRLRYSRICEPVLTQQLGVAATEQLD
MMAR_4157|M.marinum_M RGLIGANLGVGVLPQATAR----PADIIEIAIDDAQLVRPIAIGWIADRC
MUL_4020|M.ulcerans_Agy99 RGLIGANLGVGVLPQATAR----PADIIEIAIDDAQLVRPIAIGWIADRC
Mb2303c|M.bovis_AF2122/97 RAAVLAGAGPAAMSRLAIADDLAFGRLLAVDIPALNLRRQLRAIWVGGRT
Rv2282c|M.tuberculosis_H37Rv RAAVLAGAGPAAMSRLAIADDLAFGRLLAVDIPALNLRRQLRAIWVGGRT
MAB_2707|M.abscessus_ATCC_1997 AGLVAAGLGVTVLPVDATT---YPPDLRMLRLIDADAHRDVGIVWSSGQP
Mvan_3362|M.vanbaalenii_PYR-1 ADLARHGLGVAILPRSMARGSAGLHPLRLSPELRGRLVWAWRTDISGPAA
MSMEG_0708|M.smegmatis_MC2_155 KNLVAAGHGWAVLPAICLSDEMTSGKFSLAPLAEAMAMRELVLATPRTNR
MLBr_02041|M.leprae_Br4923 VQCVTGGLGVTLLPQSAAPVESVRSKLGLAQFAAPCPGRRIGLAFRSASG
TH_3504|M.thermoresistible__bu AAPLTTG---GIAFVTAAAGPTMNGRVQVVDLTPPLLVP---VQALWQRH
. .
MAV_3102|M.avium_104 LPREVTAKVGNILREETAHLIKTGRWPARLLSPQPWDPAVT
Mflv_1833|M.gilvum_PYR-GCK LPRELVVKVGNALREEIAALIRSGSWRADLLSPEPWSPRRV
MMAR_4157|M.marinum_M LPSSAVAFRETALGCYGHRVSAAGV----------------
MUL_4020|M.ulcerans_Agy99 LPSSAVAFRETAFGCYGHRDSAAGV----------------
Mb2303c|M.bovis_AF2122/97 PPAGAIRDLLSHITSRST-----------------------
Rv2282c|M.tuberculosis_H37Rv PPAGAIRDLLSHITSRST-----------------------
MAB_2707|M.abscessus_ATCC_1997 LSRPVRNFISHAVAST-------------------------
Mvan_3362|M.vanbaalenii_PYR-1 RLLNARARAMIAATGTPAVIPGA------------------
MSMEG_0708|M.smegmatis_MC2_155 STGAVRAVAGALLRILHGAALEGRWPSVVWHLGEEPEARV-
MLBr_02041|M.leprae_Br4923 RSASYRQIAKIIGELISTEHHVRLVA---------------
TH_3504|M.thermoresistible__bu TLSAIRDRILEGLG---------------------------