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MAEGDYEWYITLAELQNVTAAADQLRLAQPTLTRMLARLERRLGVQLFDRHGKRLALNPFGRIFYQHARR AQLELDSARRAIDDLANPAEGEIRLGFLHTFGPTLIAGLIAGFATTSPHVRFVLEQGAAGSLDDLVATGD LDVAIVSPRPRRANLGWRNLFRQRLGVAVPTDHRLAQAQDVSMVDLADEPFVAMHPGFGMRRLLEELCAA AQFQPRIVLESSNLMTVAGLVAAGLGVTVLPVDATTYPPDLRMLRLIDADAHRDVGIVWSSGQPLSRPVR NFISHAVAST
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2707 | - | - | 100% (290) | putative transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2680c | - | 2e-35 | 33.33% (255) | LysR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3308 | - | 3e-27 | 31.89% (254) | LysR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2303c | - | 4e-12 | 25.08% (307) | LysR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3565 | - | 3e-27 | 31.75% (252) | LysR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv2282c | - | 4e-12 | 25.08% (307) | LysR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02041 | oxyR | 1e-19 | 26.58% (237) | putative LysR-family transcriptional regulator |
| M. marinum M | MMAR_4157 | - | 1e-34 | 33.96% (265) | LuxR family transcriptional regulator |
| M. avium 104 | MAV_1538 | - | 1e-110 | 66.67% (288) | transcriptional regulator, LysR family protein |
| M. smegmatis MC2 155 | MSMEG_0104 | - | 1e-62 | 43.21% (287) | transcriptional regulator, LysR family protein |
| M. thermoresistible (build 8) | TH_3504 | - | 2e-10 | 26.89% (238) | PUTATIVE putative transcriptional regulator |
| M. ulcerans Agy99 | MUL_4020 | - | 4e-34 | 33.96% (265) | LuxR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_3362 | - | 1e-31 | 31.43% (280) | LysR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_2707|M.abscessus_ATCC_1997 -------MAEGDYEWYITLAELQNVTAAADQLRLAQPTLTRMLARLERRL
MAV_1538|M.avium_104 -------MAVGDYEWFITLAELQHVTAAAEQLHVAQPTLTRMLARLEQRL
MSMEG_0104|M.smegmatis_MC2_155 -------MHLDELSWFVVLAETEHVTDAAAELGISQPTLSRALARLEDEV
MMAR_4157|M.marinum_M -------MELYQLRYFQAVAECGTLRGASEQLLVSQSAVSRAITLLEAEI
MUL_4020|M.ulcerans_Agy99 -------MELYQLRYFQAVAECGTLRGASEQLLVSQSAVSRAITLLEAEI
Mflv_3565|M.gilvum_PYR-GCK -------MELRQLEYFVAIVEEGGFTRAASRERVAQPAVSAQIRRLERSV
Mvan_3362|M.vanbaalenii_PYR-1 -------MELRQLEYLVAVVEERSFTKAAQRERVAQPAVSAQIRRLERQV
Mb2303c|M.bovis_AF2122/97 MPLSSRMPGLTCFEIFLAIAEAGSLGGAARELGLTQQAVSRRLASMEAQI
Rv2282c|M.tuberculosis_H37Rv MPLSSRMPGLTCFEIFLAIAEAGSLGGAARELGLTQQAVSRRLASMEAQI
MLBr_02041|M.leprae_Br4923 MSDKSYQPTIAGLRAFVAVVEKGHFSAAASFLGVRQSTLSQALAALESGL
TH_3504|M.thermoresistible__bu --VPSPKIDLRRLAQFVAVAELGSFTRAAATLHLSQQALSSAVRALENDV
.:.* . *: : * ::: : :* :
MAB_2707|M.abscessus_ATCC_1997 GVQLFDRHGKRLALNPFGRIFYQHARRAQLELDSARRAIDDLANPAEGEI
MAV_1538|M.avium_104 GVALFDRHGRRLSLNTYGRIFYEHARRAQLELDSARRAIADLADPAVGEI
MSMEG_0104|M.smegmatis_MC2_155 GVPLFDRVNRRLQLNAYGEILLEHARRTITEMRSATERIAAMRDPDTGLV
MMAR_4157|M.marinum_M GVQLFTRRGRTNELNRYGQALLVGSRLAQRSVSSAIDNVRELAGVSGGTV
MUL_4020|M.ulcerans_Agy99 GVQLFTRRGRTNELNRYGQALLVGSRLAQRSVSSAIDNVRELAGVSGGTV
Mflv_3565|M.gilvum_PYR-GCK GQPLLTRTSREVRLTRAGEALLPHARAALAAVRDGRAAVDDVAGLLRGSV
Mvan_3362|M.vanbaalenii_PYR-1 GQPLLTRSHRGVRVTPAGAALLPHARAALAAVRDAQAAVDDVANLVRGAV
Mb2303c|M.bovis_AF2122/97 GVRLAIRTTRGSQLTPAGIVVAEWAARLLEVADEIDAGLGSLRTEGRQRI
Rv2282c|M.tuberculosis_H37Rv GVRLAIRTTRGSQLTPAGIVVAEWAARLLEVADEIDAGLGSLRTEGRQRI
MLBr_02041|M.leprae_Br4923 GVQLIERSTRRVFVTTQGRHLLPRAQAAIEAMDAFTAAAAGESDPLRGGM
TH_3504|M.thermoresistible__bu GADLFTRDGRRISLTTAGRTLLAEGKPLLAAARTVAEHVRQTEAAAQAHY
* * * : :. * . .
MAB_2707|M.abscessus_ATCC_1997 RLGFLHTFGPTLIAGLIAGFATTSPH-----VRFVLEQGAAGSLDDLVAT
MAV_1538|M.avium_104 RLAYLSSFGSTVVPRLIARFKESSPR-----VTFTLEEGAAESIADRVRS
MSMEG_0104|M.smegmatis_MC2_155 RLAFLHSQAGSFVPDLLRRFRAHAPH-----VQFSLTQGAAHDLLERLAG
MMAR_4157|M.marinum_M ALGFLHSLGMQTVPHLIRLHHSRFPQ-----ARFELHQRSGQGVLSDLVS
MUL_4020|M.ulcerans_Agy99 ALGFLHSLGMQTVPHLIRLHHSRFPQ-----ARFELHQRSGQGVLSDLVS
Mflv_3565|M.gilvum_PYR-GCK AIGTVT-LHPMNVAHLIAEFHADHPD-----VEITLGTATSDVLIAELGD
Mvan_3362|M.vanbaalenii_PYR-1 AIGTVT-LHPVDVARLMADFHAEHPG-----VEITLGTDTSDVLLAKLED
Mb2303c|M.bovis_AF2122/97 RVVASQTIAEQLMPHWMLSLRAADMRRGGTVPEVILTATNSEHAIAAVRD
Rv2282c|M.tuberculosis_H37Rv RVVASQTIAEQLMPHWMLSLRAADMRRGGTVPEVILTATNSEHAIAAVRD
MLBr_02041|M.leprae_Br4923 RLGLIPTVAPYVLPTMLTGLTHRLPT-----LTLRVVEDQTEHLLTALRE
TH_3504|M.thermoresistible__bu VIGHTPALSGAEAYALIEPAVTAYPS-----TSFTLRQLYPDALTDAVFD
: : . : :
MAB_2707|M.abscessus_ATCC_1997 GDLDVAIVSPRPRR--ANLGWRNLFRQRLGVAVPTDHRLAQA-QDVSMVD
MAV_1538|M.avium_104 GGVDIGVVSPRPVE--RTLAWRSLFRQRLGVAVPDGHRFARG-AAVSMVD
MSMEG_0104|M.smegmatis_MC2_155 GQVDLAITSPRP----EGFQWRGLYVERLCLAVPRGHRLASR-SRITLAD
MMAR_4157|M.marinum_M GVTDVSLSFPAAFEGYGEIAWQTLFTQQLYAVVSTDHPLAGR-RLIRFPE
MUL_4020|M.ulcerans_Agy99 GVTDVSLSFPAAFEGYGEIAWQTLFTQQLYAVVSTDHPLAGR-RLIRFPE
Mflv_3565|M.gilvum_PYR-GCK GRLDLAIVSIAVDEDLPGLEVAVITDEAVEAAVADGHPLAHR-RSLSLEQ
Mvan_3362|M.vanbaalenii_PYR-1 GRLDAAIVSIGADEDPAGLEYEVITDEALEAAVTAQHRLARR-KSLSLKQ
Mb2303c|M.bovis_AF2122/97 GIADLGFIENPCPP--TGLGSVVVARDELVVVVPPGHKWARRSRVVSARE
Rv2282c|M.tuberculosis_H37Rv GIADLGFIENPCPP--TGLGSVVVARDELVVVVPPGHKWARRSRVVSARE
MLBr_02041|M.leprae_Br4923 GALDAAMIALPVET--AGIAEIPIYDEDFVLALPPGHPLSGK-RRVPTTA
TH_3504|M.thermoresistible__bu GTVQLGLRRGVVPT--PELATAVIGYHRVRVAFVDSHPLAAR-ESVDITE
* : .. : : . . .. * : :
MAB_2707|M.abscessus_ATCC_1997 LADEPFVAMHPG--FGMRRLLEELCAAAQ----FQPRIVLESSNLMTVAG
MAV_1538|M.avium_104 LADEPFVTMHPG--FGMRRLLDELCAAAQ----FRPRVALQAPNLTTAAS
MSMEG_0104|M.smegmatis_MC2_155 AGDEPFVGLAPG--FGLRQLTEELCAEAG----ITPHVVFEATEIPTMEG
MMAR_4157|M.marinum_M LAAYPFVVLDRD--HTLRRIVDAACARHG----IDPTLAFEGTDVGTLRG
MUL_4020|M.ulcerans_Agy99 LAAYPFVVLDRD--HTLRRIVDAACARHG----IDPTPAFEGTDVGTLRG
Mflv_3565|M.gilvum_PYR-GCK LSRHPLISLPAG--TGLRTRLDTACAAAG----LRPRIAFEATSPAELAE
Mvan_3362|M.vanbaalenii_PYR-1 LCEYPVISLPAG--TGLRSRLDDACAAAG----LRPRIAFEATSPLELAD
Mb2303c|M.bovis_AF2122/97 LAQTPLVTREPN--SGIRDSLTAALRDTLGEDMQQAPPVLELSSAAAVRA
Rv2282c|M.tuberculosis_H37Rv LAQTPLVTREPN--SGIRDSLTAALRDTLGEDMQQAPPVLELSSAAAVRA
MLBr_02041|M.leprae_Br4923 LAQLPLLLLDEG--HCLRDQTLDICRKSG---VQAELANTRAASLATAVQ
TH_3504|M.thermoresistible__bu LAREQVALWAPPGTSYYSDFLMGACRRAG----FEPDYVVSRVQGAATVA
. .
MAB_2707|M.abscessus_ATCC_1997 LVAAGLGVTVLPVDAT---TYPPDLRMLRLIDADAHRDVGIVWSSGQPLS
MAV_1538|M.avium_104 LVAAGLGISLVPIDGS---SYPSGVSVKPLADADAYRDVGMIWDSGRPLP
MSMEG_0104|M.smegmatis_MC2_155 LVAAGFGVAVVPVPHAG--RAEPGAEYIALAQASAKRQLGLAWPADRPLP
MMAR_4157|M.marinum_M LIGANLGVGVLPQATA----RPADIIEIAIDDAQLVRPIAIGWIADRCLP
MUL_4020|M.ulcerans_Agy99 LIGANLGVGVLPQATA----RPADIIEIAIDDAQLVRPIAIGWIADRCLP
Mflv_3565|M.gilvum_PYR-GCK LARHGLGVAILPQSMA---RGGSGLHALRLAPELRGRLVWAWRADGANPA
Mvan_3362|M.vanbaalenii_PYR-1 LARHGLGVAILPRSMA---RGSAGLHPLRLSPELRGRLVWAWRTDISGPA
Mb2303c|M.bovis_AF2122/97 AVLAGAGPAAMSRLAIADDLAFGRLLAVDIPALNLRRQLRAIWVGGRTPP
Rv2282c|M.tuberculosis_H37Rv AVLAGAGPAAMSRLAIADDLAFGRLLAVDIPALNLRRQLRAIWVGGRTPP
MLBr_02041|M.leprae_Br4923 CVTGGLGVTLLPQSAAPVESVRSKLGLAQFAAPCPGRRIGLAFRSASGRS
TH_3504|M.thermoresistible__bu APLTTGGIAFVTAAAG-----PTMNGRVQVVDLTPPLLVPVQALWQRHTL
* :. . :
MAB_2707|M.abscessus_ATCC_1997 RPVRNFISHAVAST------------
MAV_1538|M.avium_104 RSARDFIAGAAAVGHGGW--------
MSMEG_0104|M.smegmatis_MC2_155 PAAERFAQFVIRTTHDVE--------
MMAR_4157|M.marinum_M SSAVAFRETALGCYGHRVSAAGV---
MUL_4020|M.ulcerans_Agy99 SSAVAFRETAFGCYGHRDSAAGV---
Mflv_3565|M.gilvum_PYR-GCK ARVLGERARAMAVSPGSGAPAVVPGA
Mvan_3362|M.vanbaalenii_PYR-1 ARLLNARARAMIAATG--TPAVIPGA
Mb2303c|M.bovis_AF2122/97 AGAIRDLLSHITSRST----------
Rv2282c|M.tuberculosis_H37Rv AGAIRDLLSHITSRST----------
MLBr_02041|M.leprae_Br4923 ASYRQIAKIIGELISTEHHVRLVA--
TH_3504|M.thermoresistible__bu SAIRDRILEGLG--------------