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ETTNTGRRRPGRPTGTSNTREHILTCARELFALNGLDRTSVRSVAAAAGVDASLVHHYYGTKQQLFAAAI QIPIDPTVVLEQIVETPVDELGLKIPSVPLPLWDSELSTGLVATLRALMAGTESNLARSFLQEVVTSEVG SRVDSPTGTGRIRAQFVTSQLLGVVMARHIVKIEPFASLPADQVAQAIAPTLQRYLNR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_1664 | - | - | 100% (199) | hypothetical protein MUL_1664 |
| M. ulcerans Agy99 | MUL_2781 | - | 1e-69 | 67.01% (194) | hypothetical protein MUL_2781 |
| M. ulcerans Agy99 | MUL_3981 | - | 2e-23 | 35.71% (196) | putative regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1711c | - | 2e-77 | 70.05% (197) | hypothetical protein Mb1711c |
| M. gilvum PYR-GCK | Mflv_0253 | - | 2e-25 | 33.50% (197) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1685c | - | 2e-77 | 70.05% (197) | hypothetical protein Rv1685c |
| M. leprae Br4923 | MLBr_02568 | - | 4e-06 | 25.19% (135) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2351c | - | 6e-55 | 49.21% (189) | TetR family transcriptional regulator |
| M. marinum M | MMAR_2484 | - | 1e-104 | 97.46% (197) | hypothetical protein MMAR_2484 |
| M. avium 104 | MAV_3088 | - | 3e-68 | 62.44% (197) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_3765 | - | 4e-68 | 61.93% (197) | transcriptional regulator |
| M. thermoresistible (build 8) | TH_3542 | - | 1e-21 | 32.96% (179) | PUTATIVE transcriptional regulator, TetR family |
| M. vanbaalenii PYR-1 | Mvan_3298 | - | 3e-71 | 61.54% (195) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0253|M.gilvum_PYR-GCK MPPPAQT---GRRRGRRKGDPVSRETVLAAAKGRFARDGFEKTTLRAIAE
TH_3542|M.thermoresistible__bu --------------------------VLAAAKRRFAQDGYEKTTLRAIAR
MUL_1664|M.ulcerans_Agy99 METTNTG---RRRPGRPTGTSNTREHILTCARELFALNGLDRTSVRSVAA
MMAR_2484|M.marinum_M METTNTG---RRRPGRPTGTSNTREHILTCARELFALNGLDRTSVRSVAA
Mb1711c|M.bovis_AF2122/97 MAAPDNS---RRRPGRPAGSSDTRERILSSARELFAHNGIDRTSIRAVAA
Rv1685c|M.tuberculosis_H37Rv MAAPDNS---RRRPGRPAGSSDTRERILSSARELFAHNGIDRTSIRAVAA
MSMEG_3765|M.smegmatis_MC2_155 MTATSDTGRARKRPGRPPGASDTRDRILASARELFARNGFDKTSIRAVAA
Mvan_3298|M.vanbaalenii_PYR-1 MTTNAD----RKRPGRPPGTSDTRDRILECARELFARNGITNTSIRSIAA
MAV_3088|M.avium_104 MTTTGTT---RRRRGRPAGSSGSRERILASARELFARNGIRNTSIRAVAA
MAB_2351c|M.abscessus_ATCC_199 MS--------SKRPGRRPGTSSARDDILASARKLFSLNGIDKTSIRAIAS
MLBr_02568|M.leprae_Br4923 ----------MAGGAKRIPRAVREQQMLDAAVQMFSVNGYHKTSMDAIAA
:* .* *: :* .*:: ::*
Mflv_0253|M.gilvum_PYR-GCK DAGVDASMVLYLFGSKEALFRESLRLILDPGVLIEALSGG-EADIGTRMV
TH_3542|M.thermoresistible__bu DAHVDASMVLYLFGSKAELFRESLELILDPEMLVAAMTGD-DGDVGTRMV
MUL_1664|M.ulcerans_Agy99 AAGVDASLVHHYYGTKQQLFAAAIQIPIDPTVVLEQIVETPVDELGLKIP
MMAR_2484|M.marinum_M AAGVDASLVHHYYGTKQQLFAAAIQIPIDPTVVLEQIVETPVDELGLKLP
Mb1711c|M.bovis_AF2122/97 KAGVDAALVHHYFGTKQQLFAAAIHIPIDPMVIIGPIREAPVEELGYKLP
Rv1685c|M.tuberculosis_H37Rv KAGVDAALVHHYFGTKQQLFAAAIHIPIDPMVIIGPIREAPVEELGYKLP
MSMEG_3765|M.smegmatis_MC2_155 GADVDPALVHHYFGTKTQLFAAAIHIPIDPLEVIGPLREVPVEQIGHTLP
Mvan_3298|M.vanbaalenii_PYR-1 GAGVDPALVHHYFGTKTQLFAAAIEIPIDPMSIIGPLKEVPVDQLGRALP
MAV_3088|M.avium_104 AAGVDSALVHHYFGTKEKLFAAAVQIPIDPMQVIGPLREVPVDDLGYALP
MAB_2351c|M.abscessus_ATCC_199 DAGVDPALVHHYFGTKLDLFREVVQLPVDPSVVLQPLRDVPVDELGVTIP
MLBr_02568|M.leprae_Br4923 EAQISKPMLYLYYGSKEDLFGACLNREMSRFIAMVRADIDFTQSPKDLLR
* :. .:: :*:* ** :. :. : . :
Mflv_0253|M.gilvum_PYR-GCK RAYLGVWESPESAESMRTMLASATSNPDAREAFRGFIQDYVLAAVVGTLG
TH_3542|M.thermoresistible__bu RVYLQIWESPDTGPTIRAMLQSATSNTDAREAFRSFLREYLLTAVSGVLG
MUL_1664|M.ulcerans_Agy99 SVPLPLWDS-ELSTGLVATLRALMAGTES-NLARSFLQEVVTSEVGSRVD
MMAR_2484|M.marinum_M SVLLPLWDS-ELGTGLVSTLRALMAGTES-NLARSFLQEVVTSEVGSRVD
Mb1711c|M.bovis_AF2122/97 SLLLPIWDS-ELGAGLIATLRSLISGSDV-GLARSFLEEVVTVELGSRVD
Rv1685c|M.tuberculosis_H37Rv SLLLPIWDS-ELGAGLIATLRSLISGSDV-GLARSFLEEVVTVELGSRVD
MSMEG_3765|M.smegmatis_MC2_155 RLLLPLWDS-ELGKGFIATLRSILAGNDV-SLVRSFLQEVIVGEVGSRVD
Mvan_3298|M.vanbaalenii_PYR-1 SLLLPLWDS-ELGKGFIATLRSILAGSDV-SMVRSFLQDLIATEVGGRVD
MAV_3088|M.avium_104 SMLLPLWDS-EVGAAFIATLRSILAGEEI-SLFRTFIQDVIGVEVGPRVD
MAB_2351c|M.abscessus_ATCC_199 RLIIALWDS-ELGANMLAVFRSALTGADD-GLVRVFFREVLVNIIAERVD
MLBr_02568|M.leprae_Br4923 NTIVSFLRYIDANRASWIVMYIQAMSLPAFAQTVREARDQITELVAGLMR
: . : : . .: : : :
Mflv_0253|M.gilvum_PYR-GCK G-DDRARLRAMLAASSLVGTAMMRYLMEIPPLSELATEDVIRLVAPTVTR
TH_3542|M.thermoresistible__bu G-GEQARLRAELAATGLVGTAMLRYIMRVPPLAELSTEEVVRMLAPTVNR
MUL_1664|M.ulcerans_Agy99 SPTGTGRIRAQFVTSQLLGVVMARHIVKIEPFASLPADQVAQAIAPTLQR
MMAR_2484|M.marinum_M SPTGTGRIRAQFVASQLLGVVMARHIVKIEPFASLPADQVAQAIAPTLQR
Mb1711c|M.bovis_AF2122/97 NPPGTGKIRTQFVASQLMGVVMARYIVRIEPFASLPAEQIVQTIAPNLQR
Rv1685c|M.tuberculosis_H37Rv NPPGTGKIRTQFVASQLMGVVMARYIVRIEPFASLPAEQIVQTIAPNLQR
MSMEG_3765|M.smegmatis_MC2_155 NPAGSGRIRVQYVASQLVGVVMARYILELEPFKSLPVEQIAETIGPNLQR
Mvan_3298|M.vanbaalenii_PYR-1 DPPGSGRVRVQFVASQLVGIVMARYILELEPFKSLPVEQIVDTVAPNLQR
MAV_3088|M.avium_104 NPAGSGVIRIQFVASQLVGVVMARYILELEPFASLPPEQIAATIAPNLQR
MAB_2351c|M.abscessus_ATCC_199 SPPGSGVLRAEFAITQMAGILVGRYIMAIEPLASLTAEQIALTVGPNIQR
MLBr_02568|M.leprae_Br4923 VGTRSSRPDHEYEIMAGALVGAGEAMATRLTTGDIAVDEAAELMINLFWH
. . : . .:. :: : . :
Mflv_0253|M.gilvum_PYR-GCK YLTAPADELGLPG------
TH_3542|M.thermoresistible__bu YLTADADELGLPSSLTAGS
MUL_1664|M.ulcerans_Agy99 YLNR---------------
MMAR_2484|M.marinum_M YLTGELPEEIAS-------
Mb1711c|M.bovis_AF2122/97 YLTGELPDDLAP-------
Rv1685c|M.tuberculosis_H37Rv YLTGELPDDLAP-------
MSMEG_3765|M.smegmatis_MC2_155 YLTGELPGFGALD------
Mvan_3298|M.vanbaalenii_PYR-1 YLTGELPQFSGD-------
MAV_3088|M.avium_104 YLTGDLPDGLAP-------
MAB_2351c|M.abscessus_ATCC_199 YLTGALPSITP--------
MLBr_02568|M.leprae_Br4923 GLKGAPADRDFGPSIVAG-
*.