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GKRQQSREQIEARIIELGRRQLVDRGAAGLSVRAIARDLGMVSSAVYRYVSSRDELLTLLLVDAYSDLAD TVDRARETAGEQWSDDVIAIARATRRWAVEHPACWALLYGSPVPGYHAPPERTVAAGTRVVAALFDAVAA GITTGDIRLTNDPAPQPMSSDFERIRHEFGFPGDDLVIAKCFLLWAGVLGAISLEVFGQYGADTLTDVEA VFDAQLRLLVDVLTRH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2899 | - | - | 100% (227) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_5169 | - | 1e-06 | 32.43% (74) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_1733 | - | 7e-05 | 31.82% (88) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1846 | - | 1e-102 | 80.26% (228) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_3414 | - | 2e-81 | 63.84% (224) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1816 | - | 1e-102 | 80.26% (228) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4787c | - | 3e-28 | 35.51% (214) | TetR family transcriptional regulator |
| M. marinum M | MMAR_3762 | - | 2e-06 | 30.67% (150) | AcrR family transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_3659 | - | 2e-80 | 65.35% (228) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_2336 | - | 2e-07 | 29.22% (154) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_0500 | - | 3e-06 | 27.41% (135) | transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_3167 | - | 1e-81 | 63.72% (226) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1846|M.bovis_AF2122/97 ---------MCQTCRVGKRRDAREQIEAKIVELGRRQLLDHG-AAGLSLR
Rv1816|M.tuberculosis_H37Rv ---------MCQTCRVGKRRDAREQIEAKIVELGRRQLLDHG-AAGLSLR
MAV_2899|M.avium_104 ---------------MGKRQQSREQIEARIIELGRRQLVDRG-AAGLSVR
Mflv_3414|M.gilvum_PYR-GCK ---------------MGKRQDTRERIERDIVAIGRRHLVTEG-AAGLSLR
MSMEG_3659|M.smegmatis_MC2_155 ---------------MGKRQESRERIEAAIVEIGRQHLVTEG-AAGLSMR
Mvan_3167|M.vanbaalenii_PYR-1 ---------MCDTGRVGKRQDTRDRIERQIVEIGRAHLVTHG-AAALSLR
MAB_4787c|M.abscessus_ATCC_199 ----MPTRTNAADVPATRRARQRAQTTDEIKALARRQLADGG-TGALSLR
MUL_0500|M.ulcerans_Agy99 ---------------MNRPAYHHGDLRAVILDEAARLVAQRG-ADRVSMR
MMAR_3762|M.marinum_M -------MASITRNAQANRRQRREQMECRLLEATERLMNNGASFTELSVD
TH_2336|M.thermoresistible__bu VSGVGKPISREAALLTSRASAGTGPTRQRLIEVAIELFKQHS-VAGTSLQ
. : . . *:
Mb1846|M.bovis_AF2122/97 AIARNLGMVSSAVYRYVSSRDELLTLLLVDAYSDLADTVDRARDDTVADS
Rv1816|M.tuberculosis_H37Rv AIARNLGMVSSAVYRYVSSRDELLTLLLVDAYSDLADTVDRARDDTVADS
MAV_2899|M.avium_104 AIARDLGMVSSAVYRYVSSRDELLTLLLVDAYSDLADTVDRAR-ETAGEQ
Mflv_3414|M.gilvum_PYR-GCK AIARDLGMVSSAVYRYVASRDELLTLLLVDAYTDLADTVETARAASTGD-
MSMEG_3659|M.smegmatis_MC2_155 AVARDLGMVSSAVYRYVASRDELLTLLVVDAYTELADAVAAAVADVSAAG
Mvan_3167|M.vanbaalenii_PYR-1 AIARELGMVSSAVYRYVASRDELLTLLLVDAYGELADSVERARDAAAGD-
MAB_4787c|M.abscessus_ATCC_199 GIAREMGMAPAALFRYFETQAALITALCVDANGALAQAMSDGQKAAPESD
MUL_0500|M.ulcerans_Agy99 ELARDAGVSHAAPAHHFTDRRGLFTALATQGFQLLAAALVAAR-------
MMAR_3762|M.marinum_M RLATEAGISRASFYIYFDDKGHLLRRLAGQVFDDLATGAQHWWDVAWRHD
TH_2336|M.thermoresistible__bu MISDALGLTKSAIYHHFRTRDELLTAVMEPLISEVAEIVSAAEARRGART
:: *: :: :. : *: : :*
Mb1846|M.bovis_AF2122/97 --WSDDVIAIARAVRGWAVTNPARWALLYGSPVPGYHAPPDRTAGVATRV
Rv1816|M.tuberculosis_H37Rv --WSDDVIAIARAVRGWAVTNPARWALLYGSPVPGYHAPPDRTAGVATRV
MAV_2899|M.avium_104 --WSDDVIAIARATRRWAVEHPACWALLYGSPVPGYHAPPERTVAAGTRV
Mflv_3414|M.gilvum_PYR-GCK --WREQLRALGHAIRAWAVRQPASWALLYGSPVPGYHAPRDRTVTPGTRV
MSMEG_3659|M.smegmatis_MC2_155 ARWRSQIRAIAHATRNWALDQPARWALLYGSPVPGYHAPAERTVVPGTRV
Mvan_3167|M.vanbaalenii_PYR-1 --WQDRLRAVAHATRAWAVHHPARWALLYGSPVPGYHAPREQTVGPGTRV
MAB_4787c|M.abscessus_ATCC_199 --SAARLRAAFVAARRWALAHPGDFALLSGTPIPGYAAQPAETGPAAMRV
MUL_0500|M.ulcerans_Agy99 ----GHFADAALAYVRFAIEHPGHYQVMFNRSLHDADDADLAAAQAAAAA
MMAR_3762|M.marinum_M ---PDDVRAAMRAIIARYRRHQPILIALN--EMAGYDPQTAQTYRDILTA
TH_2336|M.thermoresistible__bu -----RADHFLRGYAALAAAHREVISLLTGDPGVVALLRTRPDWAEVVQR
. : :
Mb1846|M.bovis_AF2122/97 VGAFFDAIAAGIATGDIRLTDDVAPQPMSS--DFEKIRQEFGFPGDDRVV
Rv1816|M.tuberculosis_H37Rv VGAFFDAIAAGIATGDIRLTDDVAPQPMSS--DFEKIRQEFGFPGDDRVV
MAV_2899|M.avium_104 VAALFDAVAAGITTGDIRLTNDPAPQPMSS--DFERIRHEFGFPGDDLVI
Mflv_3414|M.gilvum_PYR-GCK VAALFDVVSAGIAAGDIASGEHPAPQPLSG--DFDRLREQFGFAGDDVLL
MSMEG_3659|M.smegmatis_MC2_155 VVALFAAVARGIAEGDIPATEETVAQPLSG--DFARLRAEFGLHVDDATM
Mvan_3167|M.vanbaalenii_PYR-1 VGLLFSAIAEGVAAGAVRTSKVTVPQSLSS--DFDRLRAEFEFVADDDVV
MAB_4787c|M.abscessus_ATCC_199 IASFMDAYLRAVAAGEAVPRRTRFRPSAPGPLLVAMFGEDTAPPIDPAII
MUL_0500|M.ulcerans_Agy99 ELAAGVATLRDPGARFDPEGAQLAAWSLVHGFSTLWLNDAFDAQVRALDP
MMAR_3762|M.marinum_M ISARLARVIED-GQADGSIRPELSATTTAN-----ALTWMVERTCHQNLP
TH_2336|M.thermoresistible__bu QMALLGDVQPGPGGRVKAAVVMAGIAAAAG--------VDYGDLDEAALR
.
Mb1846|M.bovis_AF2122/97 TKCFLLWAGVVGAISLEVFGQYGADMLTDPGVVFDAQ-------------
Rv1816|M.tuberculosis_H37Rv TKCFLLWAGVVGAISLEVFGQYGADMLTDPGVVFDAQ-------------
MAV_2899|M.avium_104 AKCFLLWAGVLGAISLEVFGQYGADTLTDVEAVFDAQ-------------
Mflv_3414|M.gilvum_PYR-GCK GKCLTLWAALIGAVGLEVFGQYGPDTFADPALAFDTQ-------------
MSMEG_3659|M.smegmatis_MC2_155 ARCFALWAGLIGAVSLEVFGQYGADTLTDPRQLFDLQ-------------
Mvan_3167|M.vanbaalenii_PYR-1 ARCLVLWAALVGAISLEVFGQYGADTFADASVVFDAQ-------------
MAB_4787c|M.abscessus_ATCC_199 GIGIFAWASITGYLAGEVFGSLG-DLVADSDALYHDH-------------
MUL_0500|M.ulcerans_Agy99 MDTVLRIAMMLFKASRSGCRRFGEGCRRDEGRHHQHHDNPENHRVGVGEI
MMAR_3762|M.marinum_M SRPPEFDAELADTLSEIVWGALYLTSTSLR--------------------
TH_2336|M.thermoresistible__bu DELLAAGRRTLGLRAPHARG------------------------------
.
Mb1846|M.bovis_AF2122/97 TRLLVAVLAEH----
Rv1816|M.tuberculosis_H37Rv TRLLVAVLAEH----
MAV_2899|M.avium_104 LRLLVDVLTRH----
Mflv_3414|M.gilvum_PYR-GCK IAALTEMLCQ-----
MSMEG_3659|M.smegmatis_MC2_155 IDSLTGALTN-----
Mvan_3167|M.vanbaalenii_PYR-1 MDLVIDLFCRQGAN-
MAB_4787c|M.abscessus_ATCC_199 VDTVLCGMGFAGV--
MUL_0500|M.ulcerans_Agy99 MHHVVGEVGGEGLGR
MMAR_3762|M.marinum_M ---------------
TH_2336|M.thermoresistible__bu ---------------