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PTRTNAADVPATRRARQRAQTTDEIKALARRQLADGGTGALSLRGIAREMGMAPAALFRYFETQAALITA LCVDANGALAQAMSDGQKAAPESDSAARLRAAFVAARRWALAHPGDFALLSGTPIPGYAAQPAETGPAAM RVIASFMDAYLRAVAAGEAVPRRTRFRPSAPGPLLVAMFGEDTAPPIDPAIIGIGIFAWASITGYLAGEV FGSLGDLVADSDALYHDHVDTVLCGMGFAGV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4787c | - | - | 100% (242) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0483c | - | 1e-06 | 28.33% (180) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0499 | - | 2e-05 | 36.96% (92) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1846 | - | 5e-26 | 33.18% (214) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_3414 | - | 4e-24 | 35.07% (211) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1816 | - | 5e-26 | 33.18% (214) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_4185 | - | 3e-05 | 27.51% (189) | transcriptional regulatory protein |
| M. avium 104 | MAV_2899 | - | 4e-28 | 35.51% (214) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_3659 | - | 5e-22 | 32.75% (229) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_4549 | - | 7e-06 | 24.07% (162) | PUTATIVE putative TetR-family protein transcriptional regulator |
| M. ulcerans Agy99 | MUL_4487 | - | 2e-05 | 27.51% (189) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_3167 | - | 1e-26 | 35.81% (229) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4185|M.marinum_M -------MGRTDWLAAHRSEVAADRILDAAERLYTEHDPASIGMNEIARA
MUL_4487|M.ulcerans_Agy99 -------MGRTDWLAAHRSEVAADRILDAAERLYTEHDPASIGMNEIARA
Mflv_3414|M.gilvum_PYR-GCK -----------MGKRQDTRERIERDIVAIGRRHLVTEGAAGLSLRAIARD
MSMEG_3659|M.smegmatis_MC2_155 -----------MGKRQESRERIEAAIVEIGRQHLVTEGAAGLSMRAVARD
Mvan_3167|M.vanbaalenii_PYR-1 -----MCDTGRVGKRQDTRDRIERQIVEIGRAHLVTHGAAALSLRAIARE
Mb1846|M.bovis_AF2122/97 -----MCQTCRVGKRRDAREQIEAKIVELGRRQLLDHGAAGLSLRAIARN
Rv1816|M.tuberculosis_H37Rv -----MCQTCRVGKRRDAREQIEAKIVELGRRQLLDHGAAGLSLRAIARN
MAV_2899|M.avium_104 -----------MGKRQQSREQIEARIIELGRRQLVDRGAAGLSVRAIARD
MAB_4787c|M.abscessus_ATCC_199 MPTRTNAADVPATRRARQRAQTTDEIKALARRQLADGGTGALSLRGIARE
TH_4549|M.thermoresistible__bu -----------VDGLTEQQREQRERILRAAAEILAEQGRDAVTTRNVSAA
* . . .: . ::
MMAR_4185|M.marinum_M AGCSRATLYRYFESREALRTAYVHRETLRLGREIMQQIGDIDDPR----D
MUL_4487|M.ulcerans_Agy99 AGCSRATLYRYFESREALRTAYVHRETLRLGREIMQQIGDIDDPR----D
Mflv_3414|M.gilvum_PYR-GCK LGMVSSAVYRYVASRDELLTLLLVDAYTDLADTVETARAASTGD---WRE
MSMEG_3659|M.smegmatis_MC2_155 LGMVSSAVYRYVASRDELLTLLVVDAYTELADAVAAAVADVSAAGARWRS
Mvan_3167|M.vanbaalenii_PYR-1 LGMVSSAVYRYVASRDELLTLLLVDAYGELADSVERARDAAAGD---WQD
Mb1846|M.bovis_AF2122/97 LGMVSSAVYRYVSSRDELLTLLLVDAYSDLADTVDRARDDTVADS--WSD
Rv1816|M.tuberculosis_H37Rv LGMVSSAVYRYVSSRDELLTLLLVDAYSDLADTVDRARDDTVADS--WSD
MAV_2899|M.avium_104 LGMVSSAVYRYVSSRDELLTLLLVDAYSDLADTVDRAR-ETAGEQ--WSD
MAB_4787c|M.abscessus_ATCC_199 MGMAPAALFRYFETQAALITALCVDANGALAQAMSDGQKAAPESD--SAA
TH_4549|M.thermoresistible__bu AGVQPPTIYRHFG---DMRRLIDDAASLGMAEYLKAKRERALTDDP--VH
* .:::*:. : :. :
MMAR_4185|M.marinum_M QLITSITATLRMVRQRPALAAWFASTRPP-----IGGELAGQSEVIAGLA
MUL_4487|M.ulcerans_Agy99 QLITSITATLRMVRQRPALAAWFASTRPP-----IGGELAGQSEVIAGLA
Mflv_3414|M.gilvum_PYR-GCK QLRALGHAIRAWAVRQPASWALLYGSPVPGYHAPRDRTVTPGTRVVAALF
MSMEG_3659|M.smegmatis_MC2_155 QIRAIAHATRNWALDQPARWALLYGSPVPGYHAPAERTVVPGTRVVVALF
Mvan_3167|M.vanbaalenii_PYR-1 RLRAVAHATRAWAVHHPARWALLYGSPVPGYHAPREQTVGPGTRVVGLLF
Mb1846|M.bovis_AF2122/97 DVIAIARAVRGWAVTNPARWALLYGSPVPGYHAPPDRTAGVATRVVGAFF
Rv1816|M.tuberculosis_H37Rv DVIAIARAVRGWAVTNPARWALLYGSPVPGYHAPPDRTAGVATRVVGAFF
MAV_2899|M.avium_104 DVIAIARATRRWAVEHPACWALLYGSPVPGYHAPPERTVAAGTRVVAALF
MAB_4787c|M.abscessus_ATCC_199 RLRAAFVAARRWALAHPGDFALLSGTPIPGYAAQPAETGPAAMRVIASFM
TH_4549|M.thermoresistible__bu DLRDGWDLHVEFGLRHPATYTVLYGDPRPD---AKPRAVAEGDAILRSLM
: .*. : : . * :: :
MMAR_4185|M.marinum_M AAFLQSLGPEAPAAVERRARWTVRV------IVSLLMFPGQD--------
MUL_4487|M.ulcerans_Agy99 AAFLQSLGPEAPAAVERRARWTVRV------IVSLLMFPGQD--------
Mflv_3414|M.gilvum_PYR-GCK DVVSAGIAAGDIASGEHPAPQPLSG--DFDRLREQFGFAGDDVLLGKCLT
MSMEG_3659|M.smegmatis_MC2_155 AAVARGIAEGDIPATEETVAQPLSG--DFARLRAEFGLHVDDATMARCFA
Mvan_3167|M.vanbaalenii_PYR-1 SAIAEGVAAGAVRTSKVTVPQSLSS--DFDRLRAEFEFVADDDVVARCLV
Mb1846|M.bovis_AF2122/97 DAIAAGIATGDIRLTDDVAPQPMSS--DFEKIRQEFGFPGDDRVVTKCFL
Rv1816|M.tuberculosis_H37Rv DAIAAGIATGDIRLTDDVAPQPMSS--DFEKIRQEFGFPGDDRVVTKCFL
MAV_2899|M.avium_104 DAVAAGITTGDIRLTNDPAPQPMSS--DFERIRHEFGFPGDDLVIAKCFL
MAB_4787c|M.abscessus_ATCC_199 DAYLRAVAAGEAVPRRTRFRPSAPGPLLVAMFGEDTAPPIDPAIIGIGIF
TH_4549|M.thermoresistible__bu QRVAEAGRLRIGVDRAAEMMHSACRGVTLTLISQTPAERDPELSAATREA
. . :
MMAR_4185|M.marinum_M -------------------------------EADERAMLEEFVAPVVTPF
MUL_4487|M.ulcerans_Agy99 -------------------------------EADERAMLEEFVAPVVTPF
Mflv_3414|M.gilvum_PYR-GCK LWAALIGA----------VGLEVFGQYGPDTFADPALAFDTQIAALTEML
MSMEG_3659|M.smegmatis_MC2_155 LWAGLIGA----------VSLEVFGQYGADTLTDPRQLFDLQIDSLTGAL
Mvan_3167|M.vanbaalenii_PYR-1 LWAALVGA----------ISLEVFGQYGADTFADASVVFDAQMDLVIDLF
Mb1846|M.bovis_AF2122/97 LWAGVVGA----------ISLEVFGQYGADMLTDPGVVFDAQTRLLVAVL
Rv1816|M.tuberculosis_H37Rv LWAGVVGA----------ISLEVFGQYGADMLTDPGVVFDAQTRLLVAVL
MAV_2899|M.avium_104 LWAGVLGA----------ISLEVFGQYGADTLTDVEAVFDAQLRLLVDVL
MAB_4787c|M.abscessus_ATCC_199 AWASITGY----------LAGEVFGSLG-DLVADSDALYHDHVDTVLCGM
TH_4549|M.thermoresistible__bu MLAAITTGGAAGPADGAGVATRAIALKSVLETGGAGVLTEAEAELLKEWL
. . : :
MMAR_4185|M.marinum_M PTRR--
MUL_4487|M.ulcerans_Agy99 PTRR--
Mflv_3414|M.gilvum_PYR-GCK CQ----
MSMEG_3659|M.smegmatis_MC2_155 TN----
Mvan_3167|M.vanbaalenii_PYR-1 CRQGAN
Mb1846|M.bovis_AF2122/97 AEH---
Rv1816|M.tuberculosis_H37Rv AEH---
MAV_2899|M.avium_104 TRH---
MAB_4787c|M.abscessus_ATCC_199 GFAGV-
TH_4549|M.thermoresistible__bu DRLSQ-